locus-tag	class	description
DGN07_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DGN07_00025	COG0187	DNA topoisomerase II activity
DGN07_00035	COG0501	Belongs to the peptidase M48B family
DGN07_00075	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DGN07_00085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DGN07_00135	COG0793	Belongs to the peptidase S41A family
DGN07_00140	COG4942	peptidase
DGN07_00150	COG2234	aminopeptidase activity
DGN07_00160	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DGN07_00165	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DGN07_00175	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DGN07_00185	COG1064	alcohol dehydrogenase
DGN07_00190	COG0493	'glutamate synthase
DGN07_00195	COG0069	glutamate synthase activity
DGN07_00195	COG0070	glutamate synthase
DGN07_00195	COG0067	glutamate synthase
DGN07_00280	COG1111	helicase
DGN07_00280	COG1205	dead DEAH box helicase
DGN07_00285	COG1272	protein, Hemolysin III
DGN07_00305	COG1028	Short-chain dehydrogenase reductase Sdr
DGN07_00310	COG1028	Short-chain dehydrogenase reductase Sdr
DGN07_00335	COG2249	NAD(P)H dehydrogenase (quinone) activity
DGN07_00360	COG3039	Transposase
DGN07_00390	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DGN07_00405	COG1125	glycine betaine transport
DGN07_00405	COG0517	IMP dehydrogenase activity
DGN07_00420	COG1119	ATPase activity
DGN07_00430	COG1752	Esterase of the alpha-beta hydrolase superfamily
DGN07_00440	COG1522	sequence-specific DNA binding
DGN07_00445	COG3186	Phenylalanine-4-hydroxylase
DGN07_00455	COG2755	lipolytic protein G-D-S-L family
DGN07_00465	COG1028	Short-chain dehydrogenase reductase Sdr
DGN07_00470	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
DGN07_00485	COG1609	Transcriptional regulator
DGN07_00490	COG3507	Belongs to the glycosyl hydrolase 43 family
DGN07_00505	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DGN07_00515	COG2755	lipolytic protein G-D-S-L family
DGN07_00515	COG0657	acetylesterase activity
DGN07_00535	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DGN07_00540	COG0366	Alpha amylase catalytic
DGN07_00545	COG0366	Alpha amylase catalytic
DGN07_00575	COG3039	Transposase
DGN07_00605	COG3328	transposase activity
DGN07_00620	COG3328	transposase activity
DGN07_00630	COG3328	transposase activity
DGN07_00655	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DGN07_00660	COG3710	Transcriptional regulator
DGN07_00680	COG2197	response regulator
DGN07_00685	COG4585	Histidine kinase
DGN07_00700	COG1304	FMN binding
DGN07_00725	COG1012	belongs to the aldehyde dehydrogenase family
DGN07_00750	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
DGN07_00785	COG0714	Associated with various cellular activities
DGN07_00830	COG0477	Major facilitator Superfamily
DGN07_00840	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DGN07_00865	COG3039	Transposase
DGN07_00895	COG3237	CsbD-like
DGN07_00905	COG3039	Transposase
DGN07_00915	COG0489	protein tyrosine kinase activity
DGN07_00920	COG2062	phosphohistidine phosphatase, SixA
DGN07_00930	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DGN07_00975	COG1968	undecaprenyl-diphosphatase activity
DGN07_00985	COG0174	glutamine synthetase
DGN07_00990	COG0347	Belongs to the P(II) protein family
DGN07_00995	COG0004	ammonium transporteR
DGN07_01000	COG3852	Histidine kinase
DGN07_01005	COG2204	response regulator
DGN07_01010	COG2032	superoxide dismutase activity
DGN07_01015	COG2032	superoxide dismutase activity
DGN07_01025	COG3039	Transposase
DGN07_01040	COG0183	Belongs to the thiolase family
DGN07_01075	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DGN07_01080	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
DGN07_01085	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DGN07_01100	COG0028	Belongs to the TPP enzyme family
DGN07_01105	COG2205	protein histidine kinase activity
DGN07_01130	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DGN07_01145	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DGN07_01155	COG0596	Alpha beta hydrolase
DGN07_01160	COG0727	PFAM Uncharacterised protein family (UPF0153)
DGN07_01165	COG0318	PFAM AMP-dependent synthetase and ligase
DGN07_01170	COG0745	RESPONSE REGULATOR receiver
DGN07_01180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DGN07_01210	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DGN07_01220	COG0564	pseudouridine synthase activity
DGN07_01240	COG1446	asparaginase
DGN07_01245	COG0339	signal peptide processing
DGN07_01280	COG0475	glutathione-regulated potassium exporter activity
DGN07_01285	COG0583	DNA-binding transcription factor activity
DGN07_01290	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DGN07_01295	COG2224	Isocitrate lyase
DGN07_01325	COG4770	biotin carboxylase activity
DGN07_01330	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DGN07_01335	COG1960	acyl-CoA dehydrogenase activity
DGN07_01400	COG0697	spore germination
DGN07_01410	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DGN07_01415	COG1846	Transcriptional regulator
DGN07_01420	COG1764	response to oxidative stress
DGN07_01450	COG2130	NADP-dependent
DGN07_01465	COG1187	pseudouridine synthase activity
DGN07_01480	COG1643	Atp-dependent helicase
DGN07_01490	COG4807	Protein conserved in bacteria
DGN07_01495	COG2351	hydroxyisourate hydrolase activity
DGN07_01500	COG2072	flavoprotein involved in K transport
DGN07_01520	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DGN07_01530	COG0583	DNA-binding transcription factor activity
DGN07_01565	COG2252	PERMEase
DGN07_01610	COG0583	DNA-binding transcription factor activity
DGN07_01615	COG2814	Major facilitator Superfamily
DGN07_01625	COG2267	carboxylic ester hydrolase activity
DGN07_01630	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DGN07_01635	COG1902	pentaerythritol trinitrate reductase activity
DGN07_01655	COG0745	RESPONSE REGULATOR receiver
DGN07_01660	COG2205	protein histidine kinase activity
DGN07_01665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DGN07_01685	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DGN07_01690	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DGN07_01695	COG0583	DNA-binding transcription factor activity
DGN07_01730	COG0702	epimerase
DGN07_01735	COG1733	regulation of RNA biosynthetic process
DGN07_01740	COG3328	transposase activity
DGN07_01755	COG3039	Transposase
DGN07_01765	COG0129	dihydroxy-acid dehydratase activity
DGN07_01780	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DGN07_01835	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DGN07_01840	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DGN07_01865	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DGN07_01870	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DGN07_01880	COG3485	protocatechuate 3,4-dioxygenase
DGN07_01885	COG3485	protocatechuate 3,4-dioxygenase
DGN07_01895	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DGN07_01900	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DGN07_01915	COG1414	Transcriptional regulator
DGN07_01925	COG0657	acetylesterase activity
DGN07_01935	COG0445	tRNA wobble uridine modification
DGN07_01945	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DGN07_01975	COG1028	Short-chain dehydrogenase reductase Sdr
DGN07_01980	COG2267	carboxylic ester hydrolase activity
DGN07_01990	COG0156	8-amino-7-oxononanoate synthase activity
DGN07_01995	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DGN07_02000	COG1040	competence protein
DGN07_02005	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DGN07_02035	COG3039	Transposase
DGN07_02100	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DGN07_02190	COG1368	sulfuric ester hydrolase activity
DGN07_02195	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DGN07_02205	COG2354	Protein conserved in bacteria
DGN07_02215	COG0297	glycogen (starch) synthase activity
DGN07_02220	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DGN07_02225	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DGN07_02250	COG0702	epimerase
DGN07_02255	COG1028	Short-chain dehydrogenase reductase Sdr
DGN07_02290	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DGN07_02295	COG1028	Short-chain dehydrogenase reductase Sdr
DGN07_02305	COG0513	Belongs to the DEAD box helicase family
DGN07_02310	COG0508	dehydrogenase complex catalyzes the overall conversion of
DGN07_02325	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DGN07_02340	COG3483	tryptophan 2,3-dioxygenase activity
DGN07_02345	COG3104	oligopeptide transport
DGN07_02385	COG1320	monovalent cation:proton antiporter activity
DGN07_02390	COG2212	antiporter activity
DGN07_02400	COG0651	ATP synthesis coupled electron transport
DGN07_02405	COG1006	Multisubunit Na H antiporter MnhC subunit
DGN07_02410	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DGN07_02410	COG2111	Na H antiporter
DGN07_02435	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DGN07_02440	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
DGN07_02455	COG0456	acetyltransferase
DGN07_02460	COG1597	lipid kinase activity
DGN07_02485	COG3039	Transposase
DGN07_02500	COG3039	Transposase
DGN07_02520	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DGN07_02525	COG0134	indole-3-glycerol-phosphate synthase activity
DGN07_02535	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DGN07_02540	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
DGN07_02550	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
DGN07_02560	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DGN07_02575	COG1051	belongs to the nudix hydrolase family
DGN07_02615	COG0316	Belongs to the HesB IscA family
DGN07_02630	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DGN07_02645	COG2814	Major facilitator Superfamily
DGN07_02655	COG2814	Major facilitator Superfamily
DGN07_02660	COG1289	transmembrane transporter activity
DGN07_02665	COG0151	Belongs to the GarS family
DGN07_02675	COG0138	bifunctional purine biosynthesis protein purh
DGN07_02680	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DGN07_02690	COG0671	phosphoesterase, PA-phosphatase related
DGN07_02690	COG2453	phosphatase
DGN07_02715	COG4589	Belongs to the CDS family
DGN07_02720	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
DGN07_02745	COG2264	protein methyltransferase activity
DGN07_02765	COG0439	Biotin carboxylase
DGN07_02775	COG0511	ligase activity, forming carbon-carbon bonds
DGN07_02780	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DGN07_02790	COG1324	tolerance protein
DGN07_02800	COG2356	endonuclease I
DGN07_02810	COG0459	protein refolding
DGN07_02825	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DGN07_02840	COG3386	PFAM SMP-30 Gluconolaconase
DGN07_02850	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DGN07_02855	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DGN07_02880	COG0778	Nitroreductase
DGN07_02885	COG2353	YceI-like domain
DGN07_02915	COG3052	prosthetic group binding
DGN07_02940	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DGN07_02950	COG1802	Transcriptional regulator
DGN07_03010	COG3328	transposase activity
DGN07_03015	COG3039	Transposase
DGN07_03040	COG3039	Transposase
DGN07_03065	COG4221	oxidoreductase activity
DGN07_03080	COG4221	oxidoreductase activity
DGN07_03090	COG0435	Glutathione S-transferase
DGN07_03125	COG1506	peptidase
DGN07_03125	COG0823	Involved in the tonB-independent uptake of proteins
DGN07_03170	COG0697	spore germination
DGN07_03175	COG4305	rare lipoprotein A
DGN07_03180	COG5297	Belongs to the glycosyl hydrolase family 6
DGN07_03190	COG1113	amino acid transport
DGN07_03210	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
DGN07_03260	COG0840	transmembrane signaling receptor activity
DGN07_03265	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DGN07_03265	COG5297	Belongs to the glycosyl hydrolase family 6
DGN07_03270	COG0659	secondary active sulfate transmembrane transporter activity
DGN07_03300	COG2943	transferase activity, transferring hexosyl groups
DGN07_03310	COG3275	phosphorelay sensor kinase activity
DGN07_03320	COG0181	hydroxymethylbilane synthase activity
DGN07_03350	COG1505	serine-type exopeptidase activity
DGN07_03355	COG0436	Aminotransferase
DGN07_03365	COG2832	Protein of unknown function (DUF454)
DGN07_03375	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DGN07_03385	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DGN07_03390	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DGN07_03395	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DGN07_03420	COG2226	methyltransferase
DGN07_03425	COG3300	MHYT domain
DGN07_03425	COG5001	Diguanylate cyclase
DGN07_03430	COG0308	aminopeptidase N
DGN07_03485	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DGN07_03490	COG1077	Cell shape determining protein MreB Mrl
DGN07_03495	COG1792	Involved in formation and maintenance of cell shape
DGN07_03510	COG0772	Belongs to the SEDS family
DGN07_03520	COG2951	lytic endotransglycosylase activity
DGN07_03525	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DGN07_03535	COG1686	Belongs to the peptidase S11 family
DGN07_03545	COG2921	Belongs to the UPF0250 family
DGN07_03550	COG0321	lipoyl(octanoyl) transferase activity
DGN07_03555	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DGN07_03580	COG1051	belongs to the nudix hydrolase family
DGN07_03580	COG1056	cytidyltransferase-related domain
DGN07_03615	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
DGN07_03620	COG0673	inositol 2-dehydrogenase activity
DGN07_03625	COG2823	Periplasmic or secreted lipoprotein
DGN07_03630	COG4251	negative regulation of phosphorylation
DGN07_03635	COG0784	Response regulator, receiver
DGN07_03640	COG4191	Histidine kinase
DGN07_03645	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DGN07_03705	COG1459	type II secretion system
DGN07_03710	COG2165	general secretion pathway protein
DGN07_03725	COG4795	General secretion pathway protein
DGN07_03755	COG3250	beta-galactosidase activity
DGN07_03770	COG2188	Transcriptional regulator
DGN07_03780	COG1609	Transcriptional regulator
DGN07_03785	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DGN07_03790	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DGN07_03805	COG0617	tRNA 3'-terminal CCA addition
DGN07_03810	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
DGN07_03815	COG1012	belongs to the aldehyde dehydrogenase family
DGN07_03820	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DGN07_03835	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DGN07_03850	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DGN07_03875	COG2205	protein histidine kinase activity
DGN07_03905	COG3791	Glutathione-dependent formaldehyde-activating
DGN07_03920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DGN07_03945	COG0488	(ABC) transporter
DGN07_03955	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DGN07_03960	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DGN07_03970	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DGN07_03970	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DGN07_03990	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DGN07_03995	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DGN07_04000	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DGN07_04025	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DGN07_04030	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DGN07_04035	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DGN07_04040	COG2205	protein histidine kinase activity
DGN07_04045	COG0745	RESPONSE REGULATOR receiver
DGN07_04050	COG0277	FAD linked oxidase domain protein
DGN07_04055	COG1988	membrane-bound metal-dependent
DGN07_04060	COG0792	nuclease activity
DGN07_04090	COG0275	rRNA processing
DGN07_04095	COG3116	cell division
DGN07_04105	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DGN07_04110	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DGN07_04115	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DGN07_04125	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DGN07_04130	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DGN07_04135	COG1181	Belongs to the D-alanine--D-alanine ligase family
DGN07_04140	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DGN07_04155	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
DGN07_04165	COG0739	heme binding
DGN07_04170	COG0653	protein targeting
DGN07_04175	COG0494	nUDIX hydrolase
DGN07_04185	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DGN07_04200	COG0604	alcohol dehydrogenase
DGN07_04200	COG3321	synthase
DGN07_04200	COG1028	Short-chain dehydrogenase reductase Sdr
DGN07_04225	COG0366	Alpha amylase catalytic
DGN07_04265	COG2226	methyltransferase
DGN07_04270	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DGN07_04280	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DGN07_04320	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DGN07_04330	COG4106	trans-aconitate 2-methyltransferase activity
DGN07_04335	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DGN07_04350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DGN07_04355	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DGN07_04365	COG0667	Aldo Keto reductase
DGN07_04375	COG4771	TonB-dependent receptor
DGN07_04395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DGN07_04400	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DGN07_04410	COG2175	clavaminate synthase activity
DGN07_04420	COG4181	ATPase activity
DGN07_04435	COG0642	Histidine kinase
DGN07_04445	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DGN07_04465	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DGN07_04470	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DGN07_04485	COG3829	transcription factor binding
DGN07_04495	COG1116	anion transmembrane transporter activity
DGN07_04500	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DGN07_04510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DGN07_04520	COG0431	NADPH-dependent FMN reductase
DGN07_04540	COG0747	negative chemotaxis
DGN07_04550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DGN07_04560	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DGN07_04565	COG2967	ApaG domain
DGN07_04570	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DGN07_04575	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DGN07_04580	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DGN07_04585	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
DGN07_04610	COG0123	including yeast histone deacetylase and acetoin utilization protein
DGN07_04615	COG2096	Adenosyltransferase
DGN07_04630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DGN07_04635	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DGN07_04665	COG3384	dioxygenase
DGN07_04670	COG0583	DNA-binding transcription factor activity
DGN07_04685	COG1024	Enoyl-CoA hydratase
DGN07_04715	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
DGN07_04740	COG0697	spore germination
DGN07_04750	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DGN07_04780	COG2197	response regulator
DGN07_04790	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DGN07_04800	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DGN07_04805	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DGN07_04815	COG0583	DNA-binding transcription factor activity
DGN07_04820	COG3634	alkyl hydroperoxide reductase activity
DGN07_04830	COG2890	protein-(glutamine-N5) methyltransferase activity
DGN07_04850	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DGN07_04850	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DGN07_04875	COG3039	Transposase
DGN07_04890	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
DGN07_04935	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DGN07_04940	COG1404	Belongs to the peptidase S8 family
DGN07_04945	COG1404	Belongs to the peptidase S8 family
DGN07_04950	COG1404	Belongs to the peptidase S8 family
DGN07_04955	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DGN07_04980	COG1295	ribonuclease BN
DGN07_04985	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DGN07_04990	COG1254	Belongs to the acylphosphatase family
DGN07_05005	COG0521	Mo-molybdopterin cofactor biosynthetic process
DGN07_05015	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DGN07_05020	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DGN07_05030	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
DGN07_05035	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DGN07_05045	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DGN07_05050	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DGN07_05055	COG0193	aminoacyl-tRNA hydrolase activity
DGN07_05060	COG0012	GTP binding
DGN07_05080	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DGN07_05095	COG0250	Participates in transcription elongation, termination and antitermination
DGN07_05100	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DGN07_05105	COG0081	regulation of translation
DGN07_05110	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DGN07_05115	COG0222	ribosome binding
DGN07_05120	COG0085	RNA polymerase activity
DGN07_05125	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DGN07_05130	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DGN07_05135	COG0049	tRNA binding
DGN07_05140	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DGN07_05145	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DGN07_05150	COG0051	transcription antitermination factor activity, RNA binding
DGN07_05155	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DGN07_05160	COG0088	Forms part of the polypeptide exit tunnel
DGN07_05165	COG0089	rRNA binding
DGN07_05170	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DGN07_05175	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DGN07_05185	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DGN07_05190	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DGN07_05195	COG0255	Belongs to the universal ribosomal protein uL29 family
DGN07_05200	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DGN07_05210	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DGN07_05215	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DGN07_05225	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DGN07_05230	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DGN07_05235	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DGN07_05245	COG1841	ribosomal large subunit assembly
DGN07_05250	COG0200	Binds to the 23S rRNA
DGN07_05255	COG0201	protein transport
DGN07_05280	COG0203	ribosomal protein L17
DGN07_05285	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
DGN07_05305	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
DGN07_05320	COG0154	amidase activity
DGN07_05330	COG1217	gtp-binding protein TYPA
DGN07_05335	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DGN07_05340	COG0039	L-malate dehydrogenase activity
DGN07_05345	COG0625	glutathione transferase activity
DGN07_05365	COG0446	pyridine nucleotide-disulphide oxidoreductase
DGN07_05365	COG1902	pentaerythritol trinitrate reductase activity
DGN07_05370	COG0604	alcohol dehydrogenase
DGN07_05400	COG0156	8-amino-7-oxononanoate synthase activity
DGN07_05410	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DGN07_05415	COG4208	sulfate ABC transporter
DGN07_05420	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DGN07_05450	COG0406	alpha-ribazole phosphatase activity
DGN07_05455	COG0285	dihydrofolate synthase activity
DGN07_05475	COG2833	Protein of unknown function (DUF455)
DGN07_05495	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DGN07_05500	COG0671	phosphoesterase, PA-phosphatase related
DGN07_05505	COG0438	transferase activity, transferring glycosyl groups
DGN07_05515	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DGN07_05530	COG4783	chaperone-mediated protein folding
DGN07_05545	COG0473	3-isopropylmalate dehydrogenase activity
DGN07_05585	COG0544	peptidyl-prolyl cis-trans isomerase activity
DGN07_05595	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DGN07_05625	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DGN07_05640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DGN07_05650	COG0328	RNA-DNA hybrid ribonuclease activity
DGN07_05655	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DGN07_05660	COG0631	protein serine/threonine phosphatase activity
DGN07_05675	COG0859	PFAM glycosyl transferase family 9
DGN07_05680	COG3642	lipopolysaccharide core region biosynthetic process
DGN07_05685	COG1234	tRNA 3'-trailer cleavage
DGN07_05690	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DGN07_05700	COG0315	cyclic pyranopterin monophosphate synthase activity
DGN07_05705	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DGN07_05710	COG0314	molybdopterin synthase activity
DGN07_05745	COG2189	Belongs to the N(4) N(6)-methyltransferase family
DGN07_05815	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DGN07_05820	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DGN07_05825	COG0537	adenosine 5'-monophosphoramidase activity
DGN07_05845	COG0714	Associated with various cellular activities
DGN07_05870	COG0424	maF-like protein
DGN07_05875	COG1399	metal-binding, possibly nucleic acid-binding protein
DGN07_05885	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DGN07_05895	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DGN07_05900	COG1028	Short-chain dehydrogenase reductase Sdr
DGN07_05915	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DGN07_05920	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DGN07_05945	COG3829	transcription factor binding
DGN07_05990	COG2373	Large extracellular alpha-helical protein
DGN07_06010	COG4953	penicillin-binding protein 1C
DGN07_06020	COG0678	peroxiredoxin activity
DGN07_06040	COG0330	HflC and HflK could
DGN07_06045	COG0330	HflC and HflK could
DGN07_06065	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DGN07_06075	COG1028	Short-chain dehydrogenase reductase Sdr
DGN07_06080	COG1309	transcriptional regulator
DGN07_06125	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DGN07_06140	COG3039	Transposase
DGN07_06145	COG0732	type I restriction modification DNA specificity domain
DGN07_06160	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DGN07_06195	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DGN07_06210	COG3387	PFAM Glycoside hydrolase 15-related
DGN07_06215	COG1028	Short-chain dehydrogenase reductase Sdr
DGN07_06225	COG3537	Alpha-1,2-mannosidase
DGN07_06230	COG1028	Short-chain dehydrogenase reductase Sdr
DGN07_06245	COG0492	ferredoxin-NADP+ reductase activity
DGN07_06280	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DGN07_06285	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
DGN07_06290	COG2080	2 iron, 2 sulfur cluster binding
DGN07_06325	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DGN07_06340	COG0587	DNA-directed DNA polymerase activity
DGN07_06355	COG1297	OPT oligopeptide transporter protein
DGN07_06370	COG0823	Involved in the tonB-independent uptake of proteins
DGN07_06370	COG1506	peptidase
DGN07_06385	COG2207	Transcriptional regulator
DGN07_06385	COG1917	Cupin 2, conserved barrel domain protein
DGN07_06415	COG0753	catalase activity
DGN07_06420	COG0656	L-ascorbic acid biosynthetic process
DGN07_06430	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DGN07_06430	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DGN07_06435	COG2814	Major facilitator Superfamily
DGN07_06450	COG2194	sulfuric ester hydrolase activity
DGN07_06465	COG0745	RESPONSE REGULATOR receiver
DGN07_06470	COG0642	Histidine kinase
DGN07_06480	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
DGN07_06485	COG2894	cell division
DGN07_06490	COG0850	regulation of cytokinetic process
DGN07_06505	COG4585	Histidine kinase
DGN07_06510	COG2197	response regulator
DGN07_06525	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
DGN07_06555	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DGN07_06565	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
DGN07_06585	COG1946	Acyl-CoA thioesterase
DGN07_06600	COG0824	Thioesterase
DGN07_06605	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DGN07_06610	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DGN07_06615	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DGN07_06620	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DGN07_06625	COG0268	Binds directly to 16S ribosomal RNA
DGN07_06635	COG0196	riboflavin kinase activity
DGN07_06640	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DGN07_06645	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DGN07_06650	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DGN07_06685	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DGN07_06690	COG1845	cytochrome c oxidase, subunit III
DGN07_06695	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DGN07_06710	COG3328	transposase activity
DGN07_06715	COG3152	Membrane
DGN07_06725	COG2207	Transcriptional regulator
DGN07_06730	COG0326	Molecular chaperone. Has ATPase activity
DGN07_06740	COG1366	Belongs to the anti-sigma-factor antagonist family
DGN07_06745	COG1366	Belongs to the anti-sigma-factor antagonist family
DGN07_06750	COG2172	sigma factor antagonist activity
DGN07_06775	COG4771	TonB-dependent receptor
DGN07_06785	COG5507	3-demethylubiquinone-9 3-methyltransferase
DGN07_06795	COG2205	protein histidine kinase activity
DGN07_06805	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DGN07_06810	COG2205	protein histidine kinase activity
DGN07_06810	COG4999	Histidine kinase
DGN07_06810	COG3850	Histidine kinase
DGN07_06810	COG3437	response regulator, receiver
DGN07_06815	COG4191	Histidine kinase
DGN07_06815	COG0784	Response regulator, receiver
DGN07_06840	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DGN07_06845	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DGN07_06860	COG0228	four-way junction DNA binding
DGN07_06865	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DGN07_06870	COG0336	Belongs to the RNA methyltransferase TrmD family
DGN07_06875	COG0335	large ribosomal subunit rRNA binding
DGN07_06880	COG0534	Mate efflux family protein
DGN07_06905	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
DGN07_06915	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DGN07_06925	COG3328	transposase activity
DGN07_06940	COG3039	Transposase
DGN07_06950	COG3328	transposase activity
DGN07_06975	COG3250	beta-galactosidase activity
DGN07_06980	COG3867	Arabinogalactan endo-beta-1,4-galactanase
DGN07_07000	COG1960	acyl-CoA dehydrogenase activity
DGN07_07005	COG1024	Enoyl-CoA hydratase
DGN07_07025	COG3328	transposase activity
DGN07_07030	COG3039	Transposase
DGN07_07035	COG3039	Transposase
DGN07_07040	COG1024	Enoyl-CoA hydratase
DGN07_07040	COG1250	3-hydroxyacyl-CoA dehydrogenase
DGN07_07055	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DGN07_07060	COG0481	GTPase activity
DGN07_07075	COG0571	ribonuclease III activity
DGN07_07080	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DGN07_07085	COG1381	Involved in DNA repair and RecF pathway recombination
DGN07_07095	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DGN07_07100	COG2954	triphosphatase activity
DGN07_07105	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DGN07_07110	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
DGN07_07115	COG3046	protein related to deoxyribodipyrimidine photolyase
DGN07_07120	COG1472	Belongs to the glycosyl hydrolase 3 family
DGN07_07125	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DGN07_07130	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DGN07_07135	COG1278	Cold shock
DGN07_07140	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DGN07_07150	COG1201	RNA secondary structure unwinding
DGN07_07155	COG1793	dna ligase
DGN07_07165	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DGN07_07165	COG1793	dna ligase
DGN07_07195	COG0183	Belongs to the thiolase family
DGN07_07220	COG1451	nucleotide metabolic process
DGN07_07225	COG5487	UPF0391 membrane protein
DGN07_07235	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DGN07_07250	COG1077	Cell shape determining protein MreB Mrl
DGN07_07255	COG1047	Peptidyl-prolyl cis-trans
DGN07_07265	COG2824	Alkylphosphonate utilization operon protein PhnA
DGN07_07275	COG1902	pentaerythritol trinitrate reductase activity
DGN07_07280	COG2814	Major facilitator Superfamily
DGN07_07315	COG0392	lysyltransferase activity
DGN07_07315	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DGN07_07325	COG0251	oxidation-reduction process
DGN07_07330	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DGN07_07345	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DGN07_07370	COG1595	DNA-templated transcription, initiation
DGN07_07395	COG2878	Part of a membrane complex involved in electron transport
DGN07_07405	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DGN07_07405	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DGN07_07420	COG0582	viral genome integration into host DNA
DGN07_07440	COG3328	transposase activity
DGN07_07460	COG5314	conjugation
DGN07_07490	COG3328	transposase activity
DGN07_07505	COG1131	(ABC) transporter
DGN07_07510	COG0346	lactoylglutathione lyase activity
DGN07_07515	COG0833	amino acid
DGN07_07520	COG2040	homocysteine
DGN07_07530	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DGN07_07560	COG1695	Transcriptional regulator
DGN07_07580	COG1981	membrane
DGN07_07595	COG0825	malonyl-CoA metabolic process
DGN07_07610	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DGN07_07615	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DGN07_07620	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DGN07_07625	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DGN07_07640	COG0750	zinc metalloprotease
DGN07_07645	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DGN07_07650	COG0575	Belongs to the CDS family
DGN07_07655	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DGN07_07660	COG0233	cytoplasmic translational termination
DGN07_07665	COG0528	UMP kinase activity
DGN07_07675	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DGN07_07680	COG0052	Belongs to the universal ribosomal protein uS2 family
DGN07_07720	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
DGN07_07730	COG1393	Belongs to the ArsC family
DGN07_07735	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DGN07_07740	COG0367	asparagine synthase
DGN07_07750	COG4774	siderophore transport
DGN07_07765	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DGN07_07790	COG1566	PFAM secretion protein HlyD family protein
DGN07_07795	COG2814	Major facilitator Superfamily
DGN07_07845	COG0339	signal peptide processing
DGN07_07855	COG0386	Belongs to the glutathione peroxidase family
DGN07_07910	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DGN07_07915	COG0084	hydrolase, TatD family'
DGN07_07930	COG1960	acyl-CoA dehydrogenase activity
DGN07_07950	COG0367	asparagine synthase
DGN07_07960	COG0305	Participates in initiation and elongation during chromosome replication
DGN07_07965	COG0415	Belongs to the DNA photolyase family
DGN07_07975	COG0583	DNA-binding transcription factor activity
DGN07_08020	COG3706	GGDEF domain
DGN07_08050	COG3328	transposase activity
DGN07_08055	COG0582	viral genome integration into host DNA
DGN07_08070	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DGN07_08085	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DGN07_08095	COG0497	DNA recombination
DGN07_08100	COG1420	regulation of RNA biosynthetic process
DGN07_08105	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DGN07_08110	COG0443	Heat shock 70 kDa protein
DGN07_08115	COG0484	heat shock protein binding
DGN07_08125	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
DGN07_08155	COG0583	DNA-binding transcription factor activity
DGN07_08160	COG1132	(ABC) transporter
DGN07_08185	COG0567	Dehydrogenase, E1 component
DGN07_08195	COG2850	peptidyl-arginine hydroxylation
DGN07_08220	COG1253	flavin adenine dinucleotide binding
DGN07_08255	COG1131	(ABC) transporter
DGN07_08260	COG1725	Transcriptional regulator
DGN07_08270	COG0386	Belongs to the glutathione peroxidase family
DGN07_08285	COG2900	Belongs to the SlyX family
DGN07_08310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DGN07_08320	COG0646	methionine synthase
DGN07_08320	COG1410	methionine synthase
DGN07_08325	COG1410	methionine synthase
DGN07_08325	COG0646	methionine synthase
DGN07_08330	COG2226	methyltransferase
DGN07_08335	COG1960	acyl-CoA dehydrogenase activity
DGN07_08345	COG1960	acyl-CoA dehydrogenase activity
DGN07_08365	COG0557	exoribonuclease II activity
DGN07_08375	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DGN07_08385	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DGN07_08395	COG0704	Plays a role in the regulation of phosphate uptake
DGN07_08400	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DGN07_08405	COG0581	inorganic phosphate transmembrane transporter activity
DGN07_08410	COG0573	inorganic phosphate transmembrane transporter activity
DGN07_08415	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DGN07_08440	COG0659	secondary active sulfate transmembrane transporter activity
DGN07_08445	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DGN07_08455	COG1024	Enoyl-CoA hydratase
DGN07_08465	COG0494	nUDIX hydrolase
DGN07_08500	COG0488	(ABC) transporter
DGN07_08510	COG0116	Belongs to the methyltransferase superfamily
DGN07_08510	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DGN07_08515	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DGN07_08540	COG2925	Exonuclease
DGN07_08545	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DGN07_08550	COG3844	kynureninase activity
DGN07_08560	COG0662	Cupin 2, conserved barrel domain protein
DGN07_08565	COG0288	reversible hydration of carbon dioxide
DGN07_08660	COG0017	Asparaginyl-tRNA synthetase
DGN07_08670	COG0316	Belongs to the HesB IscA family
DGN07_08675	COG0360	Binds together with S18 to 16S ribosomal RNA
DGN07_08680	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DGN07_08685	COG0359	binds to the 23S rRNA
DGN07_08700	COG3115	cell septum assembly
DGN07_08710	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DGN07_08715	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DGN07_08720	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
DGN07_08735	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DGN07_08745	COG4993	Dehydrogenase
DGN07_08760	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DGN07_08770	COG2986	histidine ammonia-lyase
DGN07_08775	COG1228	amidohydrolase
DGN07_08815	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
DGN07_08820	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DGN07_08825	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DGN07_08830	COG0077	Prephenate dehydratase
DGN07_08830	COG1605	Chorismate mutase
DGN07_08835	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DGN07_08855	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DGN07_08860	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DGN07_08865	COG0583	DNA-binding transcription factor activity
DGN07_08880	COG3039	Transposase
DGN07_08885	COG3328	transposase activity
DGN07_08890	COG3328	transposase activity
DGN07_08900	COG0840	transmembrane signaling receptor activity
DGN07_08935	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
DGN07_08940	COG0784	Response regulator, receiver
DGN07_08940	COG4191	Histidine kinase
DGN07_08955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DGN07_08965	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
DGN07_08975	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DGN07_08990	COG1595	DNA-templated transcription, initiation
DGN07_09045	COG2244	polysaccharide biosynthetic process
DGN07_09075	COG2264	protein methyltransferase activity
DGN07_09100	COG1136	(ABC) transporter
DGN07_09110	COG2271	Major facilitator Superfamily
DGN07_09120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DGN07_09130	COG1253	flavin adenine dinucleotide binding
DGN07_09145	COG0306	phosphate transporter
DGN07_09175	COG0504	CTP synthase activity
DGN07_09190	COG0148	phosphopyruvate hydratase activity
DGN07_09195	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DGN07_09200	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DGN07_09205	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DGN07_09210	COG0585	pseudouridine synthase activity
DGN07_09215	COG2840	Smr protein MutS2
DGN07_09220	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
DGN07_09225	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DGN07_09230	COG1238	metal cluster binding
DGN07_09245	COG1534	Rna-binding protein
DGN07_09250	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
DGN07_09260	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DGN07_09265	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DGN07_09275	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DGN07_09280	COG1546	Belongs to the CinA family
DGN07_09290	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DGN07_09295	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DGN07_09305	COG2137	regulation of response to DNA damage stimulus
DGN07_09310	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DGN07_09315	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
DGN07_09335	COG1741	Belongs to the pirin family
DGN07_09340	COG0583	DNA-binding transcription factor activity
DGN07_09365	COG0351	phosphomethylpyrimidine kinase
DGN07_09380	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DGN07_09385	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DGN07_09400	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DGN07_09410	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DGN07_09415	COG3734	2-keto-3-deoxy-galactonokinase
DGN07_09425	COG4948	Mandelate Racemase Muconate Lactonizing
DGN07_09430	COG0800	Aldolase
DGN07_09470	COG1501	Belongs to the glycosyl hydrolase 31 family
DGN07_09480	COG1070	Carbohydrate kinase
DGN07_09490	COG3328	transposase activity
DGN07_09510	COG3328	transposase activity
DGN07_09540	COG3039	Transposase
DGN07_09550	COG0860	N-Acetylmuramoyl-L-alanine amidase
DGN07_09555	COG1469	GTP cyclohydrolase I activity
DGN07_09575	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DGN07_09580	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DGN07_09585	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DGN07_09610	COG1472	Belongs to the glycosyl hydrolase 3 family
DGN07_09625	COG2203	Gaf domain
DGN07_09625	COG3706	GGDEF domain
DGN07_09625	COG5001	Diguanylate cyclase
DGN07_09625	COG4251	negative regulation of phosphorylation
DGN07_09635	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
DGN07_09645	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DGN07_09665	COG1794	racemase activity, acting on amino acids and derivatives
DGN07_09675	COG0697	spore germination
DGN07_09680	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DGN07_09685	COG0167	dihydroorotate dehydrogenase activity
DGN07_09700	COG1012	belongs to the aldehyde dehydrogenase family
DGN07_09725	COG3328	transposase activity
DGN07_09745	COG3328	transposase activity
DGN07_09780	COG2856	Zn peptidase
DGN07_09810	COG1215	transferase activity, transferring glycosyl groups
DGN07_09815	COG3328	transposase activity
DGN07_09835	COG3039	Transposase
DGN07_09865	COG3039	Transposase
DGN07_09895	COG3039	Transposase
DGN07_09905	COG3328	transposase activity
DGN07_09945	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DGN07_09950	COG0124	histidyl-tRNA synthetase
DGN07_09960	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DGN07_09965	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DGN07_09970	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DGN07_09975	COG0131	Imidazoleglycerol-phosphate dehydratase
DGN07_09975	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DGN07_09980	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DGN07_09985	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DGN07_09990	COG0107	imidazoleglycerol-phosphate synthase activity
DGN07_09995	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DGN07_09995	COG0140	phosphoribosyl-ATP diphosphatase activity
DGN07_10010	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
DGN07_10015	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
DGN07_10020	COG0235	Class ii aldolase
DGN07_10025	COG0531	amino acid
DGN07_10030	COG0531	amino acid
DGN07_10040	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DGN07_10045	COG0277	FAD linked oxidase domain protein
DGN07_10065	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DGN07_10110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DGN07_10120	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DGN07_10125	COG0505	Belongs to the CarA family
DGN07_10135	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DGN07_10140	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DGN07_10150	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DGN07_10160	COG3279	Response regulator of the LytR AlgR family
DGN07_10170	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DGN07_10180	COG2205	protein histidine kinase activity
DGN07_10180	COG2198	Histidine kinase
DGN07_10180	COG0784	Response regulator, receiver
DGN07_10185	COG2198	Histidine kinase
DGN07_10185	COG2205	protein histidine kinase activity
DGN07_10185	COG0784	Response regulator, receiver
DGN07_10190	COG1024	Enoyl-CoA hydratase
DGN07_10195	COG0318	PFAM AMP-dependent synthetase and ligase
DGN07_10225	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DGN07_10235	COG2201	protein-glutamate methylesterase activity
DGN07_10240	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
DGN07_10250	COG0840	transmembrane signaling receptor activity
DGN07_10265	COG0835	chemotaxis
DGN07_10295	COG0840	transmembrane signaling receptor activity
DGN07_10300	COG0840	transmembrane signaling receptor activity
DGN07_10305	COG0840	transmembrane signaling receptor activity
DGN07_10310	COG0840	transmembrane signaling receptor activity
DGN07_10320	COG0840	transmembrane signaling receptor activity
DGN07_10330	COG0840	transmembrane signaling receptor activity
DGN07_10335	COG0840	transmembrane signaling receptor activity
DGN07_10355	COG0840	transmembrane signaling receptor activity
DGN07_10365	COG0745	RESPONSE REGULATOR receiver
DGN07_10375	COG0835	chemotaxis
DGN07_10390	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DGN07_10410	COG3039	Transposase
DGN07_10470	COG0784	Response regulator, receiver
DGN07_10470	COG2198	Histidine kinase
DGN07_10470	COG0643	Histidine kinase
DGN07_10505	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DGN07_10535	COG1684	flagellar biosynthetic protein fliR
DGN07_10565	COG3190	flagellar
DGN07_10615	COG1677	Flagellar hook-basal body complex protein FliE
DGN07_10630	COG3039	Transposase
DGN07_10660	COG1028	Short-chain dehydrogenase reductase Sdr
DGN07_10665	COG1028	Short-chain dehydrogenase reductase Sdr
DGN07_10670	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DGN07_10690	COG2201	protein-glutamate methylesterase activity
DGN07_10720	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
DGN07_10735	COG3039	Transposase
DGN07_10740	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DGN07_10750	COG1705	Flagellar rod assembly protein muramidase FlgJ
DGN07_10750	COG3951	Flagellar rod assembly protein muramidase FlgJ
DGN07_10755	COG1706	bacterial-type flagellum-dependent cell motility
DGN07_10760	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
DGN07_10770	COG4787	bacterial-type flagellum-dependent cell motility
DGN07_10780	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DGN07_10785	COG1558	bacterial-type flagellum-dependent cell motility
DGN07_10795	COG0784	Response regulator, receiver
DGN07_10795	COG0835	chemotaxis
DGN07_10825	COG5002	protein histidine kinase activity
DGN07_10855	COG2915	High frequency lysogenization protein hflD homolog
DGN07_10860	COG0482	sulfurtransferase activity
DGN07_10875	COG0542	response to heat
DGN07_10885	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
DGN07_10895	COG0492	ferredoxin-NADP+ reductase activity
DGN07_10900	COG1674	ftsk spoiiie
DGN07_10910	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DGN07_10920	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DGN07_10925	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DGN07_10935	COG0183	Belongs to the thiolase family
DGN07_10940	COG1024	Enoyl-CoA hydratase
DGN07_10940	COG1250	3-hydroxyacyl-CoA dehydrogenase
DGN07_10955	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DGN07_10965	COG1426	Protein conserved in bacteria
DGN07_10975	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DGN07_10980	COG1160	GTP binding
DGN07_10985	COG0303	'Molybdopterin
DGN07_10990	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DGN07_11025	COG0708	Exodeoxyribonuclease III
DGN07_11035	COG0303	'Molybdopterin
DGN07_11040	COG0746	molybdenum cofactor guanylyltransferase activity
DGN07_11070	COG1914	H( )-stimulated, divalent metal cation uptake system
DGN07_11085	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
DGN07_11090	COG0668	transmembrane transport
DGN07_11100	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DGN07_11115	COG1028	Short-chain dehydrogenase reductase Sdr
DGN07_11120	COG1183	phosphatidylcholine synthase activity
DGN07_11130	COG3243	poly(R)-hydroxyalkanoic acid synthase
DGN07_11145	COG0723	plastoquinol--plastocyanin reductase activity
DGN07_11145	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DGN07_11155	COG2183	response to ionizing radiation
DGN07_11160	COG0784	Response regulator, receiver
DGN07_11160	COG2205	protein histidine kinase activity
DGN07_11225	COG0800	Aldolase
DGN07_11230	COG0129	dihydroxy-acid dehydratase activity
DGN07_11235	COG0363	glucosamine-6-phosphate deaminase activity
DGN07_11240	COG0837	glucose binding
DGN07_11245	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DGN07_11255	COG0354	folic acid binding
DGN07_11270	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
DGN07_11285	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DGN07_11290	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
DGN07_11300	COG4591	ABC-type transport system involved in lipoprotein release permease component
DGN07_11305	COG1136	(ABC) transporter
DGN07_11320	COG0811	peptide transport
DGN07_11325	COG0848	biopolymer transport protein
DGN07_11330	COG1132	(ABC) transporter
DGN07_11335	COG1663	tetraacyldisaccharide 4'-kinase activity
DGN07_11340	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
DGN07_11345	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DGN07_11355	COG0322	excinuclease ABC activity
DGN07_11360	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DGN07_11375	COG3328	transposase activity
DGN07_11385	COG3328	transposase activity
DGN07_11395	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DGN07_11400	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DGN07_11415	COG0494	nUDIX hydrolase
DGN07_11420	COG0433	COG0433 Predicted ATPase
DGN07_11435	COG0688	phosphatidylethanolamine metabolic process
DGN07_11445	COG2890	protein-(glutamine-N5) methyltransferase activity
DGN07_11450	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DGN07_11455	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DGN07_11460	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DGN07_11475	COG0101	tRNA pseudouridine synthase activity
DGN07_11480	COG0135	phosphoribosylanthranilate isomerase activity
DGN07_11490	COG0133	tryptophan synthase activity
DGN07_11500	COG0159	tryptophan synthase activity
DGN07_11505	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DGN07_11510	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DGN07_11540	COG0300	oxidoreductase activity
DGN07_11545	COG0149	triose-phosphate isomerase activity
DGN07_11560	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DGN07_11565	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DGN07_11570	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DGN07_11575	COG0649	NAD binding
DGN07_11580	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
DGN07_11585	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DGN07_11595	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DGN07_11600	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DGN07_11625	COG1007	ATP synthesis coupled electron transport
DGN07_11635	COG0779	Required for maturation of 30S ribosomal subunits
DGN07_11640	COG0195	Participates in both transcription termination and antitermination
DGN07_11645	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DGN07_11650	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DGN07_11655	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DGN07_11660	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DGN07_11665	COG1185	polyribonucleotide nucleotidyltransferase activity
DGN07_11700	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DGN07_11710	COG2095	MarC family integral membrane protein
DGN07_11725	COG1611	Belongs to the LOG family
DGN07_11775	COG3328	transposase activity
DGN07_11790	COG3328	transposase activity
DGN07_11800	COG0556	nucleotide-excision repair
DGN07_11815	COG3505	Type IV secretory pathway VirD4
DGN07_11835	COG2948	multi-organism process
DGN07_11855	COG3702	type iv secretory pathway
DGN07_11900	COG3328	transposase activity
DGN07_11925	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
DGN07_11945	COG1054	Belongs to the UPF0176 family
DGN07_11955	COG1530	ribonuclease E activity
DGN07_11965	COG3064	Membrane
DGN07_11970	COG0428	transporter
DGN07_11980	COG2154	pterin-4-alpha-carbinolamine dehydratase
DGN07_11985	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
DGN07_11985	COG0316	Belongs to the HesB IscA family
DGN07_12035	COG2226	methyltransferase
DGN07_12035	COG1073	alpha beta
DGN07_12040	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
DGN07_12045	COG1028	Short-chain dehydrogenase reductase Sdr
DGN07_12180	COG1136	(ABC) transporter
DGN07_12185	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DGN07_12190	COG4221	oxidoreductase activity
DGN07_12190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DGN07_12190	COG1028	Short-chain dehydrogenase reductase Sdr
DGN07_12190	COG3321	synthase
DGN07_12195	COG3321	synthase
DGN07_12195	COG1028	Short-chain dehydrogenase reductase Sdr
DGN07_12195	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DGN07_12195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DGN07_12195	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DGN07_12200	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DGN07_12200	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DGN07_12200	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DGN07_12200	COG1028	Short-chain dehydrogenase reductase Sdr
DGN07_12200	COG3321	synthase
DGN07_12210	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DGN07_12245	COG3328	transposase activity
DGN07_12255	COG3039	Transposase
DGN07_12265	COG0583	DNA-binding transcription factor activity
DGN07_12295	COG3328	transposase activity
DGN07_12315	COG3220	belongs to the UPF0276 family
DGN07_12340	COG3920	Histidine kinase
DGN07_12380	COG3279	Response regulator of the LytR AlgR family
DGN07_12385	COG3275	phosphorelay sensor kinase activity
DGN07_12425	COG4566	intracellular signal transduction
DGN07_12435	COG5001	Diguanylate cyclase
DGN07_12455	COG3685	Protein conserved in bacteria
DGN07_12475	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DGN07_12475	COG1648	precorrin-2 dehydrogenase activity
DGN07_12490	COG2814	Major facilitator Superfamily
DGN07_12505	COG1335	isochorismatase
DGN07_12520	COG2197	response regulator
DGN07_12540	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DGN07_12550	COG3328	transposase activity
DGN07_12560	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DGN07_12560	COG0519	Catalyzes the synthesis of GMP from XMP
DGN07_12570	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DGN07_12585	COG0475	glutathione-regulated potassium exporter activity
DGN07_12585	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DGN07_12595	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DGN07_12605	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DGN07_12610	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
DGN07_12620	COG0776	regulation of translation
DGN07_12625	COG0539	negative regulation of cytoplasmic translation
DGN07_12630	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DGN07_12650	COG2957	Belongs to the agmatine deiminase family
DGN07_12655	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DGN07_12680	COG0395	ABC-type sugar transport system, permease component
DGN07_12685	COG1175	transmembrane transport
DGN07_12715	COG2350	Protein conserved in bacteria
DGN07_12720	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DGN07_12725	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DGN07_12730	COG1187	pseudouridine synthase activity
DGN07_12755	COG0436	Aminotransferase
DGN07_12760	COG4133	protoheme IX ABC transporter activity
DGN07_12780	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
DGN07_12785	COG1138	Cytochrome C-type biogenesis protein
DGN07_12805	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DGN07_12810	COG1278	Cold shock
DGN07_12815	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DGN07_12820	COG4988	ABC transporter
DGN07_12830	COG1294	oxidase, subunit
DGN07_12850	COG3328	transposase activity
DGN07_12885	COG1388	LysM domain
DGN07_12885	COG4942	peptidase
DGN07_12920	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DGN07_12925	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DGN07_12935	COG0165	Argininosuccinate lyase
DGN07_12940	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DGN07_12950	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DGN07_12955	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DGN07_12965	COG0137	argininosuccinate synthase activity
DGN07_12970	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DGN07_12980	COG0215	cysteine-tRNA ligase activity
DGN07_12985	COG2166	iron-sulfur cluster assembly
DGN07_13000	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DGN07_13005	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DGN07_13025	COG4302	ethanolamine ammonia-lyase activity
DGN07_13090	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DGN07_13095	COG0402	S-adenosylhomocysteine deaminase activity
DGN07_13105	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DGN07_13110	COG1509	lysine 2,3-aminomutase activity
DGN07_13115	COG3300	MHYT domain
DGN07_13115	COG5001	Diguanylate cyclase
DGN07_13130	COG0483	inositol monophosphate 1-phosphatase activity
DGN07_13135	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DGN07_13155	COG0488	(ABC) transporter
DGN07_13160	COG0513	Belongs to the DEAD box helicase family
DGN07_13165	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DGN07_13170	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
DGN07_13180	COG0625	glutathione transferase activity
DGN07_13190	COG4681	YaeQ
DGN07_13195	COG2081	HI0933 family
DGN07_13205	COG3039	Transposase
DGN07_13210	COG0501	Belongs to the peptidase M48B family
DGN07_13215	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DGN07_13220	COG1028	Short-chain dehydrogenase reductase Sdr
DGN07_13245	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DGN07_13250	COG0860	N-Acetylmuramoyl-L-alanine amidase
DGN07_13255	COG0802	atpase or kinase
DGN07_13260	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DGN07_13260	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DGN07_13265	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DGN07_13270	COG1570	exodeoxyribonuclease VII activity
DGN07_13285	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DGN07_13330	COG0835	chemotaxis
DGN07_13335	COG0840	transmembrane signaling receptor activity
DGN07_13340	COG2094	Belongs to the DNA glycosylase MPG family
DGN07_13345	COG1201	RNA secondary structure unwinding
DGN07_13365	COG2969	positive regulation of protein catabolic process
DGN07_13370	COG0625	glutathione transferase activity
DGN07_13375	COG2857	Cytochrome c1
DGN07_13380	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DGN07_13385	COG0723	plastoquinol--plastocyanin reductase activity
DGN07_13395	COG0741	lytic transglycosylase activity
DGN07_13410	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DGN07_13415	COG1702	phosphate starvation-inducible protein PhoH
DGN07_13425	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DGN07_13435	COG4535	Mg2 and Co2 transporter CorC
DGN07_13450	COG1012	belongs to the aldehyde dehydrogenase family
DGN07_13455	COG1177	transmembrane transport
DGN07_13460	COG1176	ABC-type spermidine putrescine transport system, permease component I
DGN07_13490	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DGN07_13505	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DGN07_13510	COG0174	glutamine synthetase
DGN07_13515	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DGN07_13525	COG2703	oxygen carrier activity
DGN07_13530	COG0477	Major facilitator Superfamily
DGN07_13545	COG0243	molybdopterin cofactor binding
DGN07_13550	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DGN07_13555	COG2223	nitrite transmembrane transporter activity
DGN07_13580	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DGN07_13590	COG2733	membrane
DGN07_13595	COG0784	Response regulator, receiver
DGN07_13595	COG2205	protein histidine kinase activity
DGN07_13595	COG5002	protein histidine kinase activity
DGN07_13610	COG0477	Major facilitator Superfamily
DGN07_13635	COG0300	oxidoreductase activity
DGN07_13645	COG1902	pentaerythritol trinitrate reductase activity
DGN07_13655	COG3321	synthase
DGN07_13655	COG0604	alcohol dehydrogenase
DGN07_13665	COG2902	Dehydrogenase
DGN07_13675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DGN07_13680	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DGN07_13685	COG1609	Transcriptional regulator
DGN07_13690	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DGN07_13690	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DGN07_13695	COG1105	Belongs to the carbohydrate kinase PfkB family
DGN07_13700	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DGN07_13700	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DGN07_13730	COG3328	transposase activity
DGN07_13765	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DGN07_13775	COG1862	Preprotein translocase
DGN07_13780	COG0343	queuine tRNA-ribosyltransferase activity
DGN07_13785	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DGN07_13825	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DGN07_13830	COG3291	Pkd domain containing protein
DGN07_13835	COG0405	Gamma-glutamyltransferase
DGN07_13840	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DGN07_13855	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DGN07_13860	COG0742	ribosomal rna small subunit methyltransferase
DGN07_13865	COG0326	Molecular chaperone. Has ATPase activity
DGN07_13875	COG3039	Transposase
DGN07_13880	COG3039	Transposase
DGN07_13970	COG0531	amino acid
DGN07_13985	COG0006	proline dipeptidase activity
DGN07_13995	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DGN07_14010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DGN07_14015	COG3938	Belongs to the proline racemase family
DGN07_14025	COG0552	protein localization to endoplasmic reticulum
DGN07_14035	COG1194	a g-specific adenine glycosylase
DGN07_14040	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
DGN07_14045	COG0784	Response regulator, receiver
DGN07_14045	COG4191	Histidine kinase
DGN07_14080	COG3039	Transposase
DGN07_14095	COG3039	Transposase
DGN07_14105	COG3039	Transposase
DGN07_14125	COG0582	viral genome integration into host DNA
DGN07_14135	COG3040	lipid binding
DGN07_14145	COG1960	acyl-CoA dehydrogenase activity
DGN07_14155	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DGN07_14175	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DGN07_14180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DGN07_14185	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DGN07_14210	COG0438	transferase activity, transferring glycosyl groups
DGN07_14220	COG0438	transferase activity, transferring glycosyl groups
DGN07_14225	COG0438	transferase activity, transferring glycosyl groups
DGN07_14275	COG0072	phenylalanine-tRNA ligase activity
DGN07_14275	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DGN07_14280	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DGN07_14295	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DGN07_14300	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DGN07_14315	COG2190	(PTS) system
DGN07_14315	COG2211	Major facilitator Superfamily
DGN07_14350	COG3039	Transposase
DGN07_14360	COG3328	transposase activity
DGN07_14385	COG0366	Alpha amylase catalytic
DGN07_14390	COG3328	transposase activity
DGN07_14445	COG0717	Belongs to the dCTP deaminase family
DGN07_14455	COG0489	protein tyrosine kinase activity
DGN07_14470	COG3039	Transposase
DGN07_14480	COG3590	peptidase
DGN07_14485	COG3590	peptidase
DGN07_14505	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DGN07_14510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DGN07_14515	COG2311	Membrane
DGN07_14520	COG1047	Peptidyl-prolyl cis-trans
DGN07_14525	COG0791	NLP P60 protein
DGN07_14530	COG0791	NLP P60 protein
DGN07_14540	COG4106	trans-aconitate 2-methyltransferase activity
DGN07_14545	COG1301	dicarboxylic acid transport
DGN07_14550	COG1785	Belongs to the alkaline phosphatase family
DGN07_14560	COG0037	tRNA processing
DGN07_14565	COG1722	exodeoxyribonuclease VII activity
DGN07_14570	COG0142	geranyltranstransferase activity
DGN07_14575	COG4104	PAAR repeat-containing protein
DGN07_14585	COG0312	modulator of DNA gyrase
DGN07_14590	COG3028	Belongs to the UPF0307 family
DGN07_14595	COG0312	modulator of DNA gyrase
DGN07_14605	COG3164	Protein of unknown function
DGN07_14615	COG0424	maF-like protein
DGN07_14620	COG2968	Membrane
DGN07_14635	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DGN07_14650	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DGN07_14665	COG0495	leucyl-tRNA aminoacylation
DGN07_14675	COG3118	belongs to the thioredoxin family
DGN07_14715	COG2155	Conserved Protein
DGN07_14720	COG3328	transposase activity
DGN07_14765	COG1132	(ABC) transporter
DGN07_14790	COG1538	Outer membrane efflux protein
DGN07_14795	COG0745	RESPONSE REGULATOR receiver
DGN07_14800	COG5000	phosphorelay sensor kinase activity
DGN07_14800	COG5002	protein histidine kinase activity
DGN07_14805	COG0475	glutathione-regulated potassium exporter activity
DGN07_14815	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DGN07_14835	COG1187	pseudouridine synthase activity
DGN07_14840	COG5001	Diguanylate cyclase
DGN07_14840	COG5002	protein histidine kinase activity
DGN07_14850	COG1595	DNA-templated transcription, initiation
DGN07_14955	COG0667	Aldo Keto reductase
DGN07_14960	COG2814	Major facilitator Superfamily
DGN07_14965	COG0583	DNA-binding transcription factor activity
DGN07_14975	COG2207	Transcriptional regulator
DGN07_14985	COG1309	transcriptional regulator
DGN07_14995	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DGN07_15010	COG0735	belongs to the Fur family
DGN07_15015	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DGN07_15040	COG4452	Inner membrane protein CreD
DGN07_15050	COG2205	protein histidine kinase activity
DGN07_15055	COG0745	RESPONSE REGULATOR receiver
DGN07_15060	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
DGN07_15070	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DGN07_15080	COG2198	Histidine kinase
DGN07_15080	COG0643	Histidine kinase
DGN07_15085	COG0840	transmembrane signaling receptor activity
DGN07_15090	COG0835	chemotaxis
DGN07_15095	COG2199	diguanylate cyclase activity
DGN07_15095	COG2200	EAL domain
DGN07_15095	COG2202	Pas domain
DGN07_15100	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DGN07_15105	COG2201	protein-glutamate methylesterase activity
DGN07_15110	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DGN07_15115	COG3590	peptidase
DGN07_15125	COG0588	phosphoglycerate mutase activity
DGN07_15130	COG1515	deoxyribonuclease V activity
DGN07_15140	COG3328	transposase activity
DGN07_15145	COG1741	Belongs to the pirin family
DGN07_15160	COG1741	Belongs to the pirin family
DGN07_15165	COG1966	Carbon starvation protein
DGN07_15170	COG2879	small protein
DGN07_15215	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DGN07_15220	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DGN07_15225	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
DGN07_15230	COG2080	2 iron, 2 sulfur cluster binding
DGN07_15235	COG0604	alcohol dehydrogenase
DGN07_15235	COG1028	Short-chain dehydrogenase reductase Sdr
DGN07_15235	COG3321	synthase
DGN07_15240	COG3706	GGDEF domain
DGN07_15240	COG4251	negative regulation of phosphorylation
DGN07_15240	COG5001	Diguanylate cyclase
DGN07_15240	COG2203	Gaf domain
DGN07_15245	COG0629	single-stranded DNA binding
DGN07_15250	COG0142	geranyltranstransferase activity
DGN07_15265	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DGN07_15280	COG0527	aspartate kinase activity
DGN07_15285	COG0384	phenazine biosynthesis protein PhzF
DGN07_15290	COG0384	phenazine biosynthesis protein PhzF
DGN07_15300	COG1764	response to oxidative stress
DGN07_15305	COG0540	Belongs to the ATCase OTCase family
DGN07_15310	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DGN07_15315	COG1678	Uncharacterized ACR, COG1678
DGN07_15325	COG0519	Catalyzes the synthesis of GMP from XMP
DGN07_15350	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DGN07_15365	COG0739	heme binding
DGN07_15385	COG0693	protein deglycase activity
DGN07_15395	COG1959	2 iron, 2 sulfur cluster binding
DGN07_15400	COG0719	Fe-S assembly protein
DGN07_15405	COG0396	ATPase activity
DGN07_15410	COG0719	Fe-S assembly protein
DGN07_15415	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DGN07_15425	COG2146	nitrite reductase [NAD(P)H] activity
DGN07_15430	COG4774	siderophore transport
DGN07_15435	COG3128	pkhd-type hydroxylase
DGN07_15460	COG1477	protein flavinylation
DGN07_15465	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DGN07_15475	COG1555	photosystem II stabilization
DGN07_15490	COG3178	'Phosphotransferase
DGN07_15495	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DGN07_15510	COG0628	permease
DGN07_15520	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DGN07_15530	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DGN07_15550	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DGN07_15555	COG0271	Belongs to the BolA IbaG family
DGN07_15565	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DGN07_15575	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
DGN07_15580	COG1137	ATPase activity
DGN07_15595	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DGN07_15600	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DGN07_15605	COG1660	Displays ATPase and GTPase activities
DGN07_15615	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DGN07_15620	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DGN07_15630	COG2239	Acts as a magnesium transporter
DGN07_15640	COG1294	oxidase, subunit
DGN07_15645	COG1271	oxidase subunit
DGN07_15655	COG1113	amino acid transport
DGN07_15665	COG3328	transposase activity
DGN07_15690	COG2197	response regulator
DGN07_15695	COG0531	amino acid
DGN07_15805	COG2814	Major facilitator Superfamily
DGN07_15820	COG0754	glutathionylspermidine amidase activity
DGN07_15845	COG1842	Phage shock protein A
DGN07_15855	COG0259	pyridoxamine-phosphate oxidase activity
DGN07_15860	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DGN07_15865	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DGN07_15875	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DGN07_15880	COG2814	Major facilitator Superfamily
DGN07_15900	COG2198	Histidine kinase
DGN07_15900	COG0784	Response regulator, receiver
DGN07_15900	COG2205	protein histidine kinase activity
DGN07_15905	COG2353	YceI-like domain
DGN07_15925	COG1760	l-serine dehydratase
DGN07_15940	COG0460	homoserine dehydrogenase
DGN07_15940	COG0527	aspartate kinase activity
DGN07_15945	COG0626	cystathionine gamma-synthase activity
DGN07_15950	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DGN07_15955	COG0739	heme binding
DGN07_15960	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DGN07_15965	COG1272	protein, Hemolysin III
DGN07_15970	COG2982	Protein involved in outer membrane biogenesis
DGN07_15975	COG0516	GMP reductase activity
DGN07_15975	COG0517	IMP dehydrogenase activity
DGN07_15980	COG0463	Glycosyl transferase, family 2
DGN07_15985	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DGN07_15990	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DGN07_16000	COG4771	TonB-dependent receptor
DGN07_16005	COG3328	transposase activity
DGN07_16015	COG3039	Transposase
DGN07_16020	COG1309	transcriptional regulator
DGN07_16030	COG1960	acyl-CoA dehydrogenase activity
DGN07_16055	COG3328	transposase activity
DGN07_16080	COG0509	glycine decarboxylation via glycine cleavage system
DGN07_16085	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DGN07_16100	COG1742	UPF0060 membrane protein
DGN07_16105	COG3956	TIGRFAM MazG family protein
DGN07_16110	COG1218	3'(2'),5'-bisphosphate nucleotidase
DGN07_16115	COG0494	nUDIX hydrolase
DGN07_16125	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DGN07_16130	COG0837	glucose binding
DGN07_16145	COG3858	chitin binding
DGN07_16145	COG1388	LysM domain
DGN07_16160	COG1472	Belongs to the glycosyl hydrolase 3 family
DGN07_16180	COG0531	amino acid
DGN07_16190	COG1486	melibiose metabolic process
DGN07_16200	COG3537	Alpha-1,2-mannosidase
DGN07_16240	COG3142	Participates in the control of copper homeostasis
DGN07_16245	COG1446	asparaginase
DGN07_16270	COG0643	Histidine kinase
DGN07_16270	COG0784	Response regulator, receiver
DGN07_16270	COG2198	Histidine kinase
DGN07_16275	COG0840	transmembrane signaling receptor activity
DGN07_16280	COG0835	chemotaxis
DGN07_16295	COG0189	ligase activity
DGN07_16305	COG1397	ADP-ribosylglycohydrolase
DGN07_16315	COG1199	ATP-dependent helicase activity
DGN07_16325	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DGN07_16330	COG1215	transferase activity, transferring glycosyl groups
DGN07_16350	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DGN07_16360	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DGN07_16365	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
DGN07_16370	COG0535	radical SAM domain protein
DGN07_16375	COG0535	radical SAM domain protein
DGN07_16390	COG0837	glucose binding
DGN07_16400	COG1643	Atp-dependent helicase
DGN07_16405	COG0783	Belongs to the Dps family
DGN07_16410	COG0514	ATP-dependent DNA helicase (RecQ)
DGN07_16450	COG0840	transmembrane signaling receptor activity
DGN07_16470	COG3920	Histidine kinase
DGN07_16475	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DGN07_16485	COG0602	queuosine metabolic process
DGN07_16495	COG2885	chlorophyll binding
DGN07_16500	COG0823	Involved in the tonB-independent uptake of proteins
DGN07_16510	COG0848	biopolymer transport protein
DGN07_16520	COG0824	Thioesterase
DGN07_16525	COG2255	four-way junction helicase activity
DGN07_16535	COG3158	transport of potassium into the cell
DGN07_16540	COG0632	four-way junction helicase activity
DGN07_16545	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DGN07_16550	COG0217	transcriptional regulatory protein
DGN07_16565	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DGN07_16580	COG0477	Major facilitator Superfamily
DGN07_16620	COG0488	(ABC) transporter
DGN07_16660	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DGN07_16660	COG4651	solute:proton antiporter activity
DGN07_16670	COG4772	TonB-dependent receptor
DGN07_16680	COG4264	IucA IucC family
DGN07_16695	COG0019	diaminopimelate decarboxylase activity
DGN07_16720	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DGN07_16730	COG1492	cobalamin metabolic process
DGN07_16740	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DGN07_16765	COG4206	TonB-dependent receptor
DGN07_16770	COG0542	response to heat
DGN07_16775	COG1116	anion transmembrane transporter activity
DGN07_16780	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DGN07_16785	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DGN07_16790	COG0667	Aldo Keto reductase
DGN07_16795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DGN07_16800	COG4771	TonB-dependent receptor
DGN07_16805	COG2827	Endonuclease containing a URI domain
DGN07_16845	COG1877	trehalose-phosphatase activity
DGN07_16850	COG3387	PFAM Glycoside hydrolase 15-related
DGN07_16870	COG0840	transmembrane signaling receptor activity
DGN07_16875	COG3011	Protein conserved in bacteria
DGN07_16890	COG0564	pseudouridine synthase activity
DGN07_16895	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DGN07_16905	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DGN07_16905	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DGN07_16920	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DGN07_16925	COG0045	succinate-CoA ligase (ADP-forming) activity
DGN07_16960	COG1459	type II secretion system
DGN07_16965	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DGN07_16970	COG0237	dephospho-CoA kinase activity
DGN07_16975	COG3039	Transposase
DGN07_16980	COG3328	transposase activity
DGN07_16990	COG3039	Transposase
DGN07_17005	COG0745	RESPONSE REGULATOR receiver
DGN07_17015	COG0189	ligase activity
DGN07_17035	COG3328	transposase activity
DGN07_17070	COG3039	Transposase
DGN07_17090	COG3328	transposase activity
DGN07_17105	COG3039	Transposase
DGN07_17110	COG3328	transposase activity
DGN07_17135	COG3039	Transposase
DGN07_17160	COG2003	Belongs to the UPF0758 family
DGN07_17190	COG3328	transposase activity
DGN07_17205	COG3039	Transposase
DGN07_17220	COG0583	DNA-binding transcription factor activity
DGN07_17225	COG1396	sequence-specific DNA binding
DGN07_17250	COG3039	Transposase
DGN07_17265	COG3328	transposase activity
DGN07_17275	COG0582	viral genome integration into host DNA
DGN07_17295	COG2022	thiamine diphosphate biosynthetic process
DGN07_17300	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DGN07_17305	COG3273	potassium ion transport
DGN07_17305	COG0471	metal ion transport
DGN07_17330	COG1970	mechanosensitive ion channel activity
DGN07_17340	COG1609	Transcriptional regulator
DGN07_17365	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DGN07_17375	COG0308	aminopeptidase N
DGN07_17380	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DGN07_17390	COG2895	sulfate adenylyltransferase (ATP) activity
DGN07_17390	COG0529	Catalyzes the synthesis of activated sulfate
DGN07_17395	COG0175	sulfate reduction
DGN07_17400	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DGN07_17405	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DGN07_17410	COG0175	sulfate reduction
DGN07_17415	COG3039	Transposase
DGN07_17435	COG2205	protein histidine kinase activity
DGN07_17435	COG2198	Histidine kinase
DGN07_17435	COG0784	Response regulator, receiver
DGN07_17455	COG1648	precorrin-2 dehydrogenase activity
DGN07_17455	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DGN07_17470	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
DGN07_17475	COG3588	fructose-bisphosphate aldolase
DGN07_17490	COG0469	pyruvate kinase activity
DGN07_17500	COG0126	phosphoglycerate kinase activity
DGN07_17530	COG3328	transposase activity
DGN07_17545	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DGN07_17555	COG3047	cAMP biosynthetic process
DGN07_17560	COG3047	cAMP biosynthetic process
DGN07_17570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DGN07_17570	COG3453	Protein conserved in bacteria
DGN07_17575	COG0725	ABC transporter, periplasmic molybdate-binding protein
DGN07_17580	COG4149	molybdate abc transporter
DGN07_17585	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
DGN07_17620	COG1376	ErfK ybiS ycfS ynhG family protein
DGN07_17625	COG0739	heme binding
DGN07_17630	COG4773	Receptor
DGN07_17640	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DGN07_17645	COG1301	dicarboxylic acid transport
DGN07_17650	COG3328	transposase activity
DGN07_17675	COG2304	oxidoreductase activity
DGN07_17695	COG0714	Associated with various cellular activities
DGN07_17730	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DGN07_17755	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DGN07_17765	COG2721	sulfolactate sulfo-lyase activity
DGN07_17780	COG2271	Major facilitator Superfamily
DGN07_17795	COG0583	DNA-binding transcription factor activity
DGN07_17800	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DGN07_17815	COG1561	YicC-like family, N-terminal region
DGN07_17820	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DGN07_17830	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DGN07_17835	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DGN07_17850	COG0006	proline dipeptidase activity
DGN07_17860	COG0006	proline dipeptidase activity
DGN07_17865	COG3079	Belongs to the UPF0149 family
DGN07_17885	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DGN07_17895	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DGN07_17905	COG2912	Transglutaminase-like superfamily
DGN07_17915	COG1773	rubredoxin
DGN07_17920	COG0352	thiamine-phosphate diphosphorylase activity
DGN07_17940	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DGN07_17955	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DGN07_17990	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DGN07_17995	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DGN07_18000	COG1028	Short-chain dehydrogenase reductase Sdr
DGN07_18010	COG0671	phosphoesterase, PA-phosphatase related
DGN07_18020	COG3781	membrane
DGN07_18030	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DGN07_18035	COG0563	adenylate kinase activity
DGN07_18050	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DGN07_18060	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DGN07_18085	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DGN07_18100	COG0840	transmembrane signaling receptor activity
DGN07_18105	COG0405	Gamma-glutamyltransferase
DGN07_18110	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DGN07_18130	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DGN07_18135	COG0473	3-isopropylmalate dehydrogenase activity
DGN07_18140	COG0066	3-isopropylmalate dehydratase activity
DGN07_18150	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DGN07_18170	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DGN07_18175	COG1538	Outer membrane efflux protein
DGN07_18180	COG1519	Transferase
DGN07_18185	COG1560	Kdo2-lipid A biosynthetic process
DGN07_18210	COG0280	phosphate acetyltransferase
DGN07_18210	COG0281	malic enzyme
DGN07_18215	COG1301	dicarboxylic acid transport
DGN07_18240	COG0583	DNA-binding transcription factor activity
DGN07_18245	COG0667	Aldo Keto reductase
DGN07_18260	COG2197	response regulator
DGN07_18270	COG0642	Histidine kinase
DGN07_18290	COG2851	Citrate transporter
DGN07_18295	COG1028	Short-chain dehydrogenase reductase Sdr
DGN07_18310	COG3039	Transposase
DGN07_18315	COG1609	Transcriptional regulator
DGN07_18320	COG2211	Major facilitator Superfamily
DGN07_18350	COG1162	GTPase activity
DGN07_18355	COG0436	Aminotransferase
DGN07_18370	COG0726	polysaccharide deacetylase
DGN07_18375	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DGN07_18390	COG3964	amidohydrolase
DGN07_18395	COG0402	S-adenosylhomocysteine deaminase activity
DGN07_18415	COG3039	Transposase
DGN07_18420	COG1307	EDD domain protein, DegV family
DGN07_18425	COG0242	peptide deformylase activity
DGN07_18450	COG0457	Tetratricopeptide repeat
DGN07_18455	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
DGN07_18460	COG1215	transferase activity, transferring glycosyl groups
DGN07_18465	COG1215	transferase activity, transferring glycosyl groups
DGN07_18480	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DGN07_18535	COG2188	Transcriptional regulator
DGN07_18545	COG1450	Type ii and iii secretion system protein
DGN07_18560	COG3166	PFAM Fimbrial assembly family protein
DGN07_18565	COG3156	type II secretion system protein K
DGN07_18570	COG4795	General secretion pathway protein
DGN07_18575	COG2165	general secretion pathway protein
DGN07_18580	COG4970	Tfp pilus assembly protein FimT
DGN07_18585	COG2165	general secretion pathway protein
DGN07_18590	COG1459	type II secretion system
DGN07_18600	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DGN07_18605	COG1404	Belongs to the peptidase S8 family
DGN07_18615	COG1404	Belongs to the peptidase S8 family
DGN07_18620	COG5295	Hep Hag repeat protein
DGN07_18625	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DGN07_18625	COG0047	phosphoribosylformylglycinamidine synthase activity
DGN07_18635	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DGN07_18650	COG4974	Belongs to the 'phage' integrase family
DGN07_18665	COG0795	lipopolysaccharide-transporting ATPase activity
DGN07_18675	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DGN07_18690	COG0525	valine-tRNA ligase activity
DGN07_18715	COG3328	transposase activity
DGN07_18735	COG1183	phosphatidylcholine synthase activity
DGN07_18745	COG0442	prolyl-tRNA aminoacylation
DGN07_18760	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DGN07_18765	COG1127	ABC transporter
DGN07_18770	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DGN07_18770	COG3218	ABC-type transport auxiliary lipoprotein component
DGN07_18800	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DGN07_18805	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
DGN07_18805	COG0662	Cupin 2, conserved barrel domain protein
DGN07_18835	COG2086	electron transfer activity
DGN07_18850	COG0463	Glycosyl transferase, family 2
DGN07_18880	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
DGN07_18885	COG0438	transferase activity, transferring glycosyl groups
DGN07_18905	COG0438	transferase activity, transferring glycosyl groups
DGN07_18915	COG0626	cystathionine gamma-synthase activity
DGN07_18945	COG0625	glutathione transferase activity
DGN07_18960	COG0513	Belongs to the DEAD box helicase family
DGN07_18970	COG4771	TonB-dependent receptor
DGN07_18975	COG3328	transposase activity
DGN07_18985	COG0720	synthase
DGN07_19010	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DGN07_19015	COG1956	GAF domain-containing protein
DGN07_19025	COG2819	hydrolase of the alpha beta superfamily
DGN07_19035	COG0546	phosphoglycolate phosphatase activity
DGN07_19040	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DGN07_19045	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DGN07_19060	COG0339	signal peptide processing
DGN07_19110	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DGN07_19115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DGN07_19120	COG1136	(ABC) transporter
DGN07_19125	COG0577	efflux transmembrane transporter activity
DGN07_19130	COG0577	efflux transmembrane transporter activity
DGN07_19130	COG1136	(ABC) transporter
DGN07_19145	COG4191	Histidine kinase
DGN07_19150	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DGN07_19170	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DGN07_19175	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DGN07_19180	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DGN07_19185	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DGN07_19190	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DGN07_19195	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DGN07_19205	COG0356	it plays a direct role in the translocation of protons across the membrane
DGN07_19225	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DGN07_19235	COG0508	dehydrogenase complex catalyzes the overall conversion of
DGN07_19275	COG2011	ABC-type metal ion transport system permease component
DGN07_19280	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DGN07_19285	COG0697	spore germination
DGN07_19290	COG1666	GTP binding
DGN07_19300	COG0784	Response regulator, receiver
DGN07_19300	COG2198	Histidine kinase
DGN07_19300	COG5002	protein histidine kinase activity
DGN07_19330	COG1187	pseudouridine synthase activity
DGN07_19335	COG2813	Specifically methylates the guanine in position
DGN07_19365	COG2202	Pas domain
DGN07_19365	COG2205	protein histidine kinase activity
DGN07_19385	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DGN07_19390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DGN07_19450	COG0842	Transport permease protein
DGN07_19455	COG1131	(ABC) transporter
DGN07_19460	COG0025	NhaP-type Na H and K H
DGN07_19470	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
DGN07_19475	COG1573	uracil-dna glycosylase
DGN07_19485	COG3384	dioxygenase
DGN07_19495	COG0583	DNA-binding transcription factor activity
DGN07_19505	COG0667	Aldo Keto reductase
DGN07_19535	COG0531	amino acid
DGN07_19550	COG2972	Histidine kinase
DGN07_19575	COG3685	Protein conserved in bacteria
DGN07_19580	COG3546	catalase activity
DGN07_19615	COG2204	response regulator
DGN07_19630	COG1271	oxidase subunit
DGN07_19635	COG1294	oxidase, subunit
DGN07_19650	COG1028	Short-chain dehydrogenase reductase Sdr
DGN07_19655	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DGN07_19675	COG1132	(ABC) transporter
DGN07_19690	COG1063	alcohol dehydrogenase
DGN07_19765	COG0251	oxidation-reduction process
DGN07_19795	COG0583	DNA-binding transcription factor activity
DGN07_19800	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DGN07_19830	COG0659	secondary active sulfate transmembrane transporter activity
DGN07_19840	COG0024	Methionine aminopeptidase
DGN07_19885	COG3039	Transposase
DGN07_19910	COG3328	transposase activity
DGN07_19930	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DGN07_19935	COG1490	D-aminoacyl-tRNA deacylase activity
DGN07_19940	COG1560	Kdo2-lipid A biosynthetic process
DGN07_19995	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DGN07_19995	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DGN07_20000	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DGN07_20005	COG0242	peptide deformylase activity
DGN07_20010	COG1652	LysM domain
DGN07_20015	COG0758	DNA mediated transformation
DGN07_20035	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DGN07_20035	COG1754	DNA topoisomerase type I activity
DGN07_20040	COG0009	L-threonylcarbamoyladenylate synthase
DGN07_20055	COG1028	Short-chain dehydrogenase reductase Sdr
DGN07_20070	COG0616	signal peptide processing
DGN07_20075	COG0534	Mate efflux family protein
DGN07_20095	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DGN07_20100	COG0625	glutathione transferase activity
DGN07_20115	COG1252	NADH dehydrogenase
DGN07_20125	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DGN07_20130	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DGN07_20135	COG3437	response regulator, receiver
DGN07_20140	COG2177	Part of the ABC transporter FtsEX involved in
DGN07_20145	COG2884	Cell division ATP-binding protein ftsE
DGN07_20150	COG0513	Belongs to the DEAD box helicase family
DGN07_20155	COG3118	belongs to the thioredoxin family
DGN07_20160	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DGN07_20165	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
DGN07_20170	COG0583	DNA-binding transcription factor activity
DGN07_20190	COG1652	LysM domain
DGN07_20195	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DGN07_20195	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DGN07_20200	COG1473	amidohydrolase
DGN07_20205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DGN07_20210	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DGN07_20230	COG5383	Protein conserved in bacteria
DGN07_20270	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
DGN07_20275	COG3023	N-Acetylmuramoyl-L-alanine amidase
DGN07_20285	COG4948	Mandelate Racemase Muconate Lactonizing
DGN07_20295	COG0531	amino acid
DGN07_20320	COG3328	transposase activity
DGN07_20330	COG2133	pyrroloquinoline quinone binding
DGN07_20340	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DGN07_20345	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DGN07_20355	COG1610	YqeY-like protein
DGN07_20365	COG1295	ribonuclease BN
DGN07_20370	COG0358	DNA primase activity
DGN07_20385	COG0109	protoheme IX farnesyltransferase activity
DGN07_20415	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
DGN07_20430	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DGN07_20475	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DGN07_20480	COG0739	heme binding
DGN07_20485	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
DGN07_20495	COG2211	Major facilitator Superfamily
DGN07_20500	COG0708	Exodeoxyribonuclease III
DGN07_20505	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DGN07_20515	COG1192	Involved in chromosome partitioning
DGN07_20520	COG1475	DNA binding
DGN07_20540	COG0463	Glycosyl transferase, family 2
DGN07_20560	COG0756	dUTP diphosphatase activity
DGN07_20565	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DGN07_20570	COG2003	Belongs to the UPF0758 family
DGN07_20575	COG0018	arginyl-trna synthetase
DGN07_20590	COG4221	oxidoreductase activity
DGN07_20595	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DGN07_20595	COG2755	lipolytic protein G-D-S-L family
DGN07_20615	COG1166	arginine decarboxylase activity
DGN07_20620	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DGN07_20645	COG3291	Pkd domain containing protein
DGN07_20645	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DGN07_20680	COG4943	cyclic-guanylate-specific phosphodiesterase activity
DGN07_20715	COG3039	Transposase
DGN07_20725	COG1690	Belongs to the RtcB family
DGN07_20760	COG1090	epimerase
DGN07_20770	COG0642	Histidine kinase
DGN07_20795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DGN07_20820	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DGN07_20825	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DGN07_20845	COG3328	transposase activity
DGN07_20865	COG0753	catalase activity
DGN07_20880	COG2197	response regulator
DGN07_20885	COG4585	Histidine kinase
DGN07_20890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DGN07_20895	COG1136	(ABC) transporter
DGN07_20920	COG0697	spore germination
DGN07_20940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DGN07_20945	COG0180	Tryptophanyl-tRNA synthetase
DGN07_20950	COG3237	CsbD-like
DGN07_20990	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DGN07_21010	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DGN07_21060	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DGN07_21090	COG1199	ATP-dependent helicase activity
DGN07_21105	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DGN07_21175	COG0625	glutathione transferase activity
DGN07_21210	COG4555	ABC transporter
DGN07_21220	COG1476	TRANSCRIPTIONal
DGN07_21240	COG1230	cation diffusion facilitator family transporter
DGN07_21250	COG4774	siderophore transport
DGN07_21265	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DGN07_21270	COG1131	(ABC) transporter
DGN07_21275	COG0842	Transport permease protein
DGN07_21280	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DGN07_21310	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DGN07_21320	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DGN07_21330	COG0045	succinate-CoA ligase (ADP-forming) activity
DGN07_21330	COG1042	CoA-binding domain protein
DGN07_21330	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DGN07_21335	COG2239	Acts as a magnesium transporter
DGN07_21355	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DGN07_21360	COG3387	PFAM Glycoside hydrolase 15-related
DGN07_21375	COG3100	YcgL domain-containing protein
DGN07_21380	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DGN07_21390	COG0463	Glycosyl transferase, family 2
DGN07_21400	COG1028	Short-chain dehydrogenase reductase Sdr
DGN07_21435	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DGN07_21450	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DGN07_21480	COG0823	Involved in the tonB-independent uptake of proteins
DGN07_21480	COG4946	Tricorn protease homolog
DGN07_21480	COG1506	peptidase
DGN07_21515	COG0408	coproporphyrinogen oxidase activity
DGN07_21555	COG0515	serine threonine protein kinase
DGN07_21620	COG1595	DNA-templated transcription, initiation
DGN07_21735	COG0210	DNA helicase
DGN07_21745	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DGN07_21750	COG0583	DNA-binding transcription factor activity
DGN07_21755	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DGN07_21795	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DGN07_21815	COG0357	Ribosomal RNA small subunit methyltransferase G
DGN07_21820	COG3540	Alkaline phosphatase
DGN07_21830	COG2091	lysine biosynthetic process via aminoadipic acid
DGN07_21845	COG0708	Exodeoxyribonuclease III
DGN07_21850	COG1846	Transcriptional regulator
DGN07_21850	COG1940	carbohydrate kinase activity
DGN07_21860	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DGN07_21875	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DGN07_21880	COG3162	membrane
DGN07_21890	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DGN07_21940	COG1028	Short-chain dehydrogenase reductase Sdr
DGN07_21945	COG0179	Fumarylacetoacetate (FAA) hydrolase
DGN07_21950	COG4948	Mandelate Racemase Muconate Lactonizing
DGN07_21955	COG3254	rhamnose metabolic process
DGN07_21960	COG0738	Major facilitator superfamily
DGN07_21965	COG1414	Transcriptional regulator
DGN07_21970	COG1971	Probably functions as a manganese efflux pump
DGN07_21975	COG2205	protein histidine kinase activity
DGN07_21990	COG3459	Glycosyltransferase 36 associated
DGN07_21995	COG2211	Major facilitator Superfamily
DGN07_22000	COG3265	gluconokinase activity
DGN07_22010	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DGN07_22035	COG2911	Protein conserved in bacteria
DGN07_22040	COG0729	surface antigen
DGN07_22050	COG3039	Transposase
DGN07_22055	COG3039	Transposase
DGN07_22070	COG3039	Transposase
DGN07_22095	COG0752	glycyl-tRNA synthetase alpha subunit
DGN07_22100	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DGN07_22120	COG0519	Catalyzes the synthesis of GMP from XMP
DGN07_22120	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DGN07_22130	COG0805	protein transport
DGN07_22135	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DGN07_22140	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DGN07_22150	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DGN07_22170	COG2974	May be involved in recombination
DGN07_22175	COG0037	tRNA processing
DGN07_22185	COG2115	Belongs to the xylose isomerase family
DGN07_22195	COG3661	Belongs to the glycosyl hydrolase 67 family
DGN07_22205	COG4948	Mandelate Racemase Muconate Lactonizing
DGN07_22215	COG1472	Belongs to the glycosyl hydrolase 3 family
DGN07_22220	COG0246	Mannitol dehydrogenase
DGN07_22300	COG3386	PFAM SMP-30 Gluconolaconase
DGN07_22310	COG3250	beta-galactosidase activity
DGN07_22315	COG1904	glucuronate isomerase
DGN07_22330	COG3693	PFAM glycoside hydrolase, family 10
DGN07_22345	COG2211	Major facilitator Superfamily
DGN07_22380	COG3321	synthase
DGN07_22380	COG0604	alcohol dehydrogenase
DGN07_22380	COG1028	Short-chain dehydrogenase reductase Sdr
DGN07_22385	COG2937	Belongs to the GPAT DAPAT family
DGN07_22420	COG0284	orotidine-5'-phosphate decarboxylase activity
DGN07_22425	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
DGN07_22430	COG3132	Protein of unknown function, DUF480
DGN07_22455	COG0210	DNA helicase
DGN07_22460	COG1435	thymidine kinase activity
DGN07_22470	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
DGN07_22480	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DGN07_22510	COG3135	benzoate transporter
DGN07_22535	COG0676	glucose-6-phosphate 1-epimerase activity
DGN07_22545	COG3012	SEC-C Motif Domain Protein
DGN07_22550	COG0730	response to heat
DGN07_22575	COG0302	gtp cyclohydrolase
DGN07_22590	COG1566	PFAM secretion protein HlyD family protein
DGN07_22600	COG1289	transmembrane transporter activity
DGN07_22605	COG0477	Major facilitator Superfamily
DGN07_22615	COG0583	DNA-binding transcription factor activity
DGN07_22620	COG4221	oxidoreductase activity
DGN07_22630	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DGN07_22665	COG3328	transposase activity
DGN07_22690	COG0564	pseudouridine synthase activity
DGN07_22720	COG3039	Transposase
DGN07_22730	COG3039	Transposase
DGN07_22765	COG1028	Short-chain dehydrogenase reductase Sdr
DGN07_22815	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DGN07_22820	COG1074	ATP-dependent DNA helicase activity
DGN07_22825	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
DGN07_22860	COG1127	ABC transporter
DGN07_22865	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DGN07_22870	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DGN07_22885	COG2853	Lipoprotein
DGN07_22895	COG0386	Belongs to the glutathione peroxidase family
DGN07_22925	COG0625	glutathione transferase activity
DGN07_22970	COG3077	Addiction module antitoxin, RelB DinJ family
DGN07_22975	COG3041	Addiction module toxin RelE StbE family
DGN07_23035	COG0840	transmembrane signaling receptor activity
DGN07_23065	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DGN07_23070	COG4691	Plasmid stability protein
DGN07_23095	COG3328	transposase activity
DGN07_23120	COG1192	Involved in chromosome partitioning
DGN07_23140	COG3537	Alpha-1,2-mannosidase
DGN07_23165	COG1929	Belongs to the glycerate kinase type-1 family
DGN07_23170	COG2271	Major facilitator Superfamily
DGN07_23185	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DGN07_23195	COG0861	Integral membrane protein TerC family
DGN07_23205	COG0584	glycerophosphoryl diester phosphodiesterase
DGN07_23215	COG3039	Transposase
DGN07_23225	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DGN07_23235	COG0706	membrane insertase activity
DGN07_23240	COG0594	ribonuclease P activity
DGN07_23325	COG3328	transposase activity
DGN07_23330	COG3328	transposase activity
DGN07_23380	COG3328	transposase activity
DGN07_23460	COG2951	lytic endotransglycosylase activity
DGN07_23635	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DGN07_23640	COG4691	Plasmid stability protein
DGN07_23645	COG1487	ribonuclease activity