locus-tag	class	description
AC612_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
AC612_00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AC612_00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AC612_00030	ENOG4108K0D	peptidase, M48
AC612_00070	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
AC612_00080	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
AC612_00105	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
AC612_00125	ENOG4105CN1	protease
AC612_00130	ENOG41063SB	peptidase
AC612_00140	ENOG4107VAM	peptidase, m28
AC612_00165	ENOG4105DQ4	alcohol dehydrogenase
AC612_00170	ENOG4105BZ8	glutamate synthase
AC612_00175	ENOG4105CBC	glutamate synthase
AC612_00255	ENOG4108I5C	dEAD DEAH box helicase
AC612_00260	ENOG4108UT2	hemolysin iii
AC612_00275	ENOG4105E1F	short-chain dehydrogenase reductase
AC612_00280	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
AC612_00300	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
AC612_00315	ENOG4105F2I	Transposase
AC612_00320	ENOG4105F2I	Transposase
AC612_00360	ENOG4105E90	ABC transporter
AC612_00365	ENOG4108IJ8	ABC transporter
AC612_00380	ENOG4105DKW	ABC transporter
AC612_00390	ENOG4105D78	K07001 NTE family protein
AC612_00395	ENOG4105CNM	Receptor
AC612_00400	ENOG4108YXU	transcriptional regulator AsnC family
AC612_00405	ENOG4105MIR	Phenylalanine 4-monooxygenase
AC612_00415	ENOG4107TDE	lipolytic protein G-D-S-L family
AC612_00425	ENOG4105CHR	reductase
AC612_00430	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
AC612_00435	ENOG4105ETE	Transcriptional regulator (LacI family
AC612_00440	ENOG4105DSG	hydrolase family 43
AC612_00445	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AC612_00455	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
AC612_00470	ENOG4105EBR	Carboxylesterase
AC612_00485	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AC612_00490	ENOG4105CG3	alpha amylase, catalytic region
AC612_00495	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
AC612_00510	ENOG4105F2I	Transposase
AC612_00535	ENOG4105D5G	Transposase
AC612_00540	ENOG4105F2I	Transposase
AC612_00550	ENOG4105D5G	Transposase
AC612_00575	ENOG4105RKW	reductase (By
AC612_00580	ENOG4108M3R	transcriptional activator CadC
AC612_00600	ENOG4105WH1	Two component transcriptional regulator luxr family
AC612_00605	ENOG4105BZU	Histidine kinase
AC612_00610	ENOG41066YJ	Beta-lactamase
AC612_00615	ENOG4105DMF	Dehydrogenase
AC612_00640	ENOG4105C26	Dehydrogenase
AC612_00650	ENOG4105F2I	Transposase
AC612_00660	ENOG4105CHB	tonB-dependent Receptor
AC612_00665	ENOG4105CGF	Aromatic amino acid aminotransferase
AC612_00670	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AC612_00700	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AC612_00740	ENOG4105CSH	Transporter
AC612_00745	ENOG4105K63	Thioredoxin
AC612_00765	ENOG4105F2I	Transposase
AC612_00800	ENOG41067RQ	csbd family
AC612_00810	ENOG4105F2I	Transposase
AC612_00825	ENOG4105D1F	ATP-binding protein
AC612_00830	ENOG4105M4E	phosphohistidine phosphatase, SixA
AC612_00840	ENOG4107RZC	phospholipase d
AC612_00845	ENOG4105KA0	thioesterase Superfamily protein
AC612_00885	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
AC612_00890	ENOG4105C5F	glutamine synthetase
AC612_00900	ENOG4105BZU	Histidine kinase
AC612_00905	ENOG4105CUX	Signal transduction histidine kinase
AC612_00910	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AC612_00915	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AC612_00920	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AC612_00930	ENOG4105F2I	Transposase
AC612_00940	ENOG4105CHU	acetyl-coa acetyltransferase
AC612_00975	ENOG4107YZP	Rhodanese domain protein
AC612_00980	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
AC612_00985	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
AC612_00995	ENOG4105C7K	acetolactate synthase
AC612_01000	ENOG4108TQ9	Histidine kinase
AC612_01005	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AC612_01025	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
AC612_01040	ENOG4105E2T	synthase III
AC612_01050	ENOG4108J2P	Alpha beta hydrolase fold
AC612_01055	ENOG4105PI0	Ferredoxin
AC612_01060	ENOG410680H	amp-dependent synthetase and ligase
AC612_01065	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AC612_01070	ENOG4107S1E	Beta-lactamase
AC612_01075	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
AC612_01100	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
AC612_01110	ENOG4105DR9	pseudouridine synthase
AC612_01120	ENOG4108YZN	class I peptide chain release factor
AC612_01130	ENOG4105D44	asparaginase
AC612_01135	ENOG4105DGW	oligopeptidase A
AC612_01170	ENOG4107R11	Transcriptional regulator
AC612_01175	ENOG4107QP3	malate synthase g
AC612_01185	ENOG4105BZU	Histidine kinase
AC612_01200	ENOG4105F2I	Transposase
AC612_01235	ENOG4107QX3	carboxylase
AC612_01240	ENOG4105C1G	acyl-Coa dehydrogenase
AC612_01310	ENOG4108TZV	Membrane
AC612_01320	ENOG4105D6Z	AFG1 family ATPase
AC612_01325	ENOG4105K56	Transcriptional regulator
AC612_01330	ENOG4108ZHJ	Organic hydroperoxide resistance protein
AC612_01360	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
AC612_01375	ENOG4108R99	pseudouridine synthase
AC612_01380	ENOG4108KPZ	tonB-dependent Receptor
AC612_01390	ENOG4105CQ7	ATP-dependent helicase
AC612_01395	ENOG4108W15	Protein of unknown function (DUF1456)
AC612_01400	ENOG4105VT2	5-hydroxyisourate hydrolase
AC612_01405	ENOG4105E1J	oxidoreductase
AC612_01425	ENOG4105C5R	Aminotransferase
AC612_01435	ENOG4105HEI	LysR family (Transcriptional regulator
AC612_01450	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
AC612_01460	ENOG4105DU0	nucleoside hydrolase
AC612_01470	ENOG4105C7N	Xanthine uracil vitamin C permease
AC612_01490	ENOG4105ETT	transcriptional Regulator, LysR family
AC612_01510	ENOG4106NZI	LysR family Transcriptional regulator
AC612_01515	ENOG4105D94	Major Facilitator Superfamily
AC612_01525	ENOG4107S9D	Alpha beta hydrolase
AC612_01530	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
AC612_01535	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AC612_01555	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
AC612_01560	ENOG4105EB3	Histidine kinase
AC612_01565	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AC612_01570	ENOG4105BZS	acriflavin resistance protein
AC612_01575	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
AC612_01585	ENOG4105DAE	Methylenetetrahydrofolate reductase
AC612_01590	ENOG4105WPN	DNA integration recombination invertion protein
AC612_01595	ENOG4105DZ2	Transcriptional regulator
AC612_01600	ENOG4108UZX	fmn reductase
AC612_01615	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
AC612_01630	ENOG4105ECR	NmrA family
AC612_01655	ENOG4105F2I	Transposase
AC612_01680	ENOG4105D5G	Transposase
AC612_01705	ENOG4105F2I	Transposase
AC612_01715	ENOG4105C01	Dihydroxy-acid dehydratase
AC612_01735	ENOG4108Z0R	Transferase
AC612_01745	ENOG4105D2S	major facilitator superfamily
AC612_01750	ENOG4105CPI	Metal Dependent Phosphohydrolase
AC612_01780	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
AC612_01790	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
AC612_01795	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
AC612_01800	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
AC612_01805	ENOG4105E98	transcriptional regulator DeoR family
AC612_01830	ENOG4105CHU	acetyl-coa acetyltransferase
AC612_01845	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
AC612_01850	ENOG4105F2Z	3-oxoadipate enol-lactonase
AC612_01855	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
AC612_01865	ENOG4107HP6	Transcriptional regulator
AC612_01880	ENOG4105MH3	Protein of unknown function (DUF2490)
AC612_01885	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
AC612_01925	ENOG4105CHR	reductase
AC612_01930	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
AC612_01940	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AC612_01945	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
AC612_01950	ENOG41081UC	Inherit from COG: Competence protein
AC612_01955	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
AC612_01980	ENOG4105F2I	Transposase
AC612_02020	ENOG4105VS8	Flagellar biosynthetic protein fliq
AC612_02040	ENOG4108HR8	type iii secretion
AC612_02060	ENOG4107Y59	type iii secretion
AC612_02075	ENOG4108JIR	Flagellum-specific ATP synthase
AC612_02085	ENOG4108TN6	type iii secretion
AC612_02090	ENOG4105K44	type iii secretion
AC612_02100	ENOG4105FTC	Lytic transglycosylase catalytic
AC612_02115	ENOG4105EGS	Mechanosensitive ion channel
AC612_02120	ENOG4107RES	phosphoglycerol transferase I
AC612_02135	ENOG4105CKW	Inner membrane protein yedI
AC612_02140	ENOG4105BZU	Histidine kinase
AC612_02145	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
AC612_02150	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AC612_02155	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AC612_02180	ENOG4105K4T	epimerase
AC612_02220	ENOG4105BZS	acriflavin resistance protein
AC612_02225	ENOG4105CHR	reductase
AC612_02235	ENOG4105C1J	atp-dependent rna helicase
AC612_02240	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
AC612_02250	ENOG4105CPP	Dehydrogenase, E1 component
AC612_02255	ENOG4107RUY	(E1 component), alpha subunit
AC612_02265	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
AC612_02270	ENOG4105DUX	Transporter
AC612_02285	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
AC612_02305	ENOG4105KJM	monovalent cation h antiporter subunit g
AC612_02310	ENOG4105W4C	monovalent cation H antiporter subunit F
AC612_02320	ENOG4107R4Z	monovalent cation h antiporter subunit d
AC612_02325	ENOG4108ZE9	Monovalent cation H antiporter subunit C
AC612_02330	ENOG4105D65	subunit l
AC612_02355	ENOG4105C8V	SAICAR synthetase
AC612_02360	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
AC612_02375	ENOG4105KD7	acetyltransferase
AC612_02380	ENOG4107TE5	Lipid kinase
AC612_02385	ENOG4105CRQ	synthase (Component I)
AC612_02400	ENOG4105F2I	Transposase
AC612_02405	ENOG4105F2I	Transposase
AC612_02410	ENOG4105F2I	Transposase
AC612_02420	ENOG4105F2I	Transposase
AC612_02430	ENOG4105DDQ	anthranilate synthase
AC612_02440	ENOG4108I0Q	anthranilate phosphoribosyltransferase
AC612_02445	ENOG4105DK0	Indole-3-glycerol phosphate synthase
AC612_02455	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
AC612_02460	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
AC612_02470	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
AC612_02475	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
AC612_02480	ENOG4108UJD	30S ribosomal protein S9
AC612_02495	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
AC612_02505	ENOG4108UQY	Iron-storage protein
AC612_02510	ENOG4105BZU	Histidine kinase
AC612_02535	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
AC612_02550	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
AC612_02565	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
AC612_02580	ENOG4105EM2	membrane
AC612_02590	ENOG4105C12	Phosphoribosylglycinamide synthetase
AC612_02600	ENOG4105DC1	bifunctional purine biosynthesis protein purh
AC612_02605	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
AC612_02615	ENOG41077RS	Phosphatase
AC612_02640	ENOG4108HPI	phosphatidate Cytidylyltransferase
AC612_02645	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
AC612_02670	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AC612_02685	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AC612_02695	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
AC612_02700	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
AC612_02705	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
AC612_02710	ENOG4105VF7	tolerance protein
AC612_02715	ENOG4108K8S	endonuclease I
AC612_02720	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
AC612_02740	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
AC612_02765	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
AC612_02770	ENOG4105EX9	Membrane
AC612_02800	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
AC612_02805	ENOG4108YYC	ycei family
AC612_02835	ENOG4105WSE	Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity)
AC612_02850	ENOG41065ZS	Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme- A to the apo- acyl-carrier-protein of the malonate decarboxylase to yield holo- acyl-carrier-protein (By similarity)
AC612_02855	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
AC612_02860	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
AC612_02870	ENOG4105DRR	Transcriptional regulator, GntR family
AC612_02910	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
AC612_02920	ENOG4105D5G	Transposase
AC612_02935	ENOG4105F2I	Transposase
AC612_02945	ENOG4107GJV	short-chain dehydrogenase reductase
AC612_02960	ENOG4105PDP	Short chain dehydrogenase
AC612_02970	ENOG4105CHF	Glutathione S-transferase
AC612_03005	ENOG4105C5Z	peptidase
AC612_03010	ENOG4107QS8	(LipO)protein
AC612_03015	ENOG4105BZU	Histidine kinase
AC612_03035	ENOG4105DFI	Membrane
AC612_03040	ENOG4108YQE	rare lipoprotein a
AC612_03050	ENOG41065HY	1,4-beta-cellobiosidase
AC612_03065	ENOG4105C85	amino acid
AC612_03075	ENOG4105D7N	magnesium and cobalt transport protein CorA
AC612_03085	ENOG4105E53	ec 3.2.1.28
AC612_03115	ENOG4105BZU	Histidine kinase
AC612_03120	ENOG4105C8Q	Methyl-accepting chemotaxis
AC612_03125	ENOG4106R7G	Glycoside hydrolase family 5
AC612_03130	ENOG4105CHH	sulfate transporter
AC612_03145	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
AC612_03155	ENOG4108HRK	Histidine kinase
AC612_03160	ENOG4108NEV	two component transcriptional regulator, LytTR family
AC612_03165	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
AC612_03205	ENOG4105WD1	Membrane
AC612_03215	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
AC612_03225	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AC612_03230	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
AC612_03235	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
AC612_03260	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AC612_03265	ENOG4105BZU	Histidine kinase
AC612_03270	ENOG4105CD8	aminopeptidase N
AC612_03290	ENOG4108Q1J	Extracellular solute-binding protein, family 3
AC612_03325	ENOG4105DFF	Rod shape-determining protein mreb
AC612_03330	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
AC612_03345	ENOG4105CNI	cell division protein FtsW
AC612_03355	ENOG4105CVE	Lytic murein transglycosylase
AC612_03360	ENOG4105K6T	rare lipoprotein A
AC612_03365	ENOG4105DZ1	carboxypeptidase
AC612_03380	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
AC612_03385	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
AC612_03390	ENOG4105CN1	protease
AC612_03400	ENOG4108KSA	LysR family transcriptional regulator
AC612_03445	ENOG4108J5G	6-phosphogluconate dehydrogenase
AC612_03450	ENOG4105D9R	oxidoreductase
AC612_03455	ENOG4105W4M	Transport-associated protein
AC612_03460	ENOG4105BZU	Histidine kinase
AC612_03470	ENOG4105BZU	Histidine kinase
AC612_03480	ENOG4105CHR	reductase
AC612_03520	ENOG4105GVR	general secretion pathway protein D
AC612_03525	ENOG4107QHF	type ii secretion system protein e
AC612_03530	ENOG4105D7Q	type ii secretion system
AC612_03535	ENOG4108VAU	general secretion pathway protein G
AC612_03540	ENOG4105VWV	general secretion pathway protein h
AC612_03545	ENOG4105X5Z	General secretion pathway protein I
AC612_03555	ENOG4108RTD	type II secretion system protein K
AC612_03580	ENOG4105CNT	hydrolase family 2
AC612_03595	ENOG4105FDP	GntR family transcriptional regulator
AC612_03605	ENOG4105ETE	Transcriptional regulator (LacI family
AC612_03610	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AC612_03615	ENOG4105CE4	GlcNAc 6-P deacetylase
AC612_03630	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AC612_03635	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
AC612_03640	ENOG4105C26	Dehydrogenase
AC612_03645	ENOG4105C94	Transporter
AC612_03655	ENOG4108Z33	Thiol disulfide Interchange Protein
AC612_03665	ENOG4106RE7	Cytochrome
AC612_03670	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
AC612_03695	ENOG4105JJR	Histidine kinase
AC612_03700	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AC612_03725	ENOG4108QBQ	Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione (By similarity)
AC612_03735	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AC612_03740	ENOG4105JAB	phenazine biosynthesis protein, phzf family
AC612_03755	ENOG4105C5H	ABC transporter
AC612_03765	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AC612_03770	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
AC612_03780	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
AC612_03795	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
AC612_03800	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
AC612_03805	ENOG4107YIM	Involved in the transcription termination process (By similarity)
AC612_03810	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
AC612_03830	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
AC612_03835	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
AC612_03840	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
AC612_03845	ENOG4105C08	Histidine kinase
AC612_03850	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
AC612_03855	ENOG4105CQB	FAD linked oxidase domain protein
AC612_03860	ENOG4105S2T	inner membrane protein YbcI
AC612_03865	ENOG41082RQ	UPF0102 protein
AC612_03885	ENOG4108V6E	Cell division protein mraZ
AC612_03890	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
AC612_03895	ENOG4106932	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
AC612_03900	ENOG4105CJN	penicillin-binding protein
AC612_03905	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
AC612_03910	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
AC612_03915	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
AC612_03925	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
AC612_03930	ENOG4105DFU	Cell wall formation (By similarity)
AC612_03935	ENOG4105CPF	Cell wall formation (By similarity)
AC612_03940	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
AC612_03945	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
AC612_03950	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AC612_03955	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AC612_03965	ENOG4105DR5	peptidase
AC612_03970	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AC612_03975	ENOG4105M6F	mutator MutT protein
AC612_03985	ENOG4105SYT	Methylenetetrahydrofolate reductase
AC612_04050	ENOG4105DXX	methyltransferase
AC612_04055	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
AC612_04065	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
AC612_04100	ENOG4105D6F	Phosphatase
AC612_04105	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
AC612_04115	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
AC612_04120	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AC612_04130	ENOG4108RVA	ribokinase
AC612_04135	ENOG4105D9N	nucleoside
AC612_04145	ENOG4105CPC	Aldo Keto reductase
AC612_04155	ENOG4105D05	Receptor
AC612_04175	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
AC612_04190	ENOG4105E2B	Taurine dioxygenase
AC612_04200	ENOG4108I0Y	(ABC) transporter
AC612_04205	ENOG4108UJV	acyl-CoA thioesterase i
AC612_04210	ENOG4105ETX	regulatoR
AC612_04215	ENOG4105DHQ	Histidine kinase
AC612_04225	ENOG41080IJ	Diacylglycerol kinase
AC612_04245	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
AC612_04250	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
AC612_04265	ENOG4107SM7	Transcriptional regulator
AC612_04270	ENOG4107T8P	acyl-Coa dehydrogenase
AC612_04275	ENOG4105D7T	ABC transporter
AC612_04280	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
AC612_04290	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
AC612_04295	ENOG4108UZX	fmn reductase
AC612_04315	ENOG4105DEF	Extracellular solute-binding protein, family 5
AC612_04325	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AC612_04335	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
AC612_04340	ENOG4105NWN	ApaG protein
AC612_04345	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
AC612_04350	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
AC612_04355	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
AC612_04360	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
AC612_04380	ENOG4108WBT	adenosyltransferase
AC612_04390	ENOG4105D0A	hydroxylase
AC612_04395	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
AC612_04430	ENOG4105DDW	LysR family Transcriptional regulator
AC612_04445	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
AC612_04475	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
AC612_04500	ENOG4105DXC	membrane
AC612_04510	ENOG4105CX6	glutaminyL-tRNA synthetase
AC612_04525	ENOG4105BZU	Histidine kinase
AC612_04530	ENOG4105BZU	Histidine kinase
AC612_04535	ENOG4105WH1	Two component transcriptional regulator luxr family
AC612_04545	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
AC612_04555	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
AC612_04560	ENOG4105NXH	GreA GreB family elongation factor
AC612_04565	ENOG4105C5Q	Transcriptional regulator
AC612_04580	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
AC612_04600	ENOG4105C2M	dna polymerase I
AC612_04620	ENOG4105F2I	Transposase
AC612_04635	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
AC612_04655	ENOG4105W8H	transhydrogenase (subunit alpha
AC612_04660	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
AC612_04675	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AC612_04680	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AC612_04685	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AC612_04690	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AC612_04695	ENOG4108Z66	YbaK ebsC protein
AC612_04715	ENOG4105CS1	NAD(P)H quinone oxidoreductase
AC612_04720	ENOG4107S2Z	UPF0761 membrane protein
AC612_04725	ENOG4107QX9	Thiol disulfide interChange protein
AC612_04740	ENOG4105CSR	polyphosphate kinase 2
AC612_04745	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
AC612_04755	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
AC612_04760	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
AC612_04765	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
AC612_04770	ENOG4105QVB	outer membrane lipoprotein LolB
AC612_04775	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
AC612_04785	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AC612_04790	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
AC612_04795	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
AC612_04800	ENOG4105C3G	gtp-binding protein
AC612_04820	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AC612_04830	ENOG4105PM1	preprotein translocase subunit SecE
AC612_04835	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
AC612_04840	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
AC612_04845	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
AC612_04850	ENOG4108VZM	50s ribosomal protein L10
AC612_04855	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
AC612_04860	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AC612_04865	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AC612_04870	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
AC612_04875	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
AC612_04880	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AC612_04885	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AC612_04890	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
AC612_04895	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
AC612_04900	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
AC612_04905	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
AC612_04910	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AC612_04915	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
AC612_04920	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
AC612_04925	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
AC612_04930	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
AC612_04940	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
AC612_04945	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
AC612_04950	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
AC612_04955	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AC612_04960	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
AC612_04965	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
AC612_04970	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
AC612_04975	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
AC612_04980	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
AC612_04990	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
AC612_04995	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
AC612_05000	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AC612_05005	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
AC612_05010	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
AC612_05015	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AC612_05020	ENOG4108ZT0	50S ribosomal protein l17
AC612_05025	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
AC612_05040	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
AC612_05050	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AC612_05065	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
AC612_05070	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
AC612_05075	ENOG4108K3A	Glutathione S-transferase
AC612_05090	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AC612_05095	ENOG4105CIS	alcohol dehydrogenase
AC612_05100	ENOG4105CDV	Ompa motb domain protein
AC612_05110	ENOG4108R99	pseudouridine synthase
AC612_05120	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AC612_05125	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
AC612_05130	ENOG4108I5D	sulfate abc transporter
AC612_05140	ENOG4108IJ6	ABC transporter
AC612_05150	ENOG4105CPQ	Dehydrogenase
AC612_05160	ENOG4105HSS	phospholipase C
AC612_05170	ENOG4105CVJ	phosphoglycerate mutase
AC612_05175	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
AC612_05190	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
AC612_05195	ENOG4105ED9	Protein of unknown function (DUF455)
AC612_05210	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
AC612_05215	ENOG4105EYK	Phosphatidylglycerophosphatase B
AC612_05220	ENOG4105BZF	Glycosyl transferase (Group 1
AC612_05225	ENOG4105C9X	ppx gppa phosphatase
AC612_05230	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
AC612_05235	ENOG4105BZU	Histidine kinase
AC612_05240	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AC612_05245	ENOG4105ERG	peptidase m48, ste24p
AC612_05250	ENOG4105VW4	glutaredoxin 3
AC612_05260	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AC612_05300	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
AC612_05305	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AC612_05310	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
AC612_05340	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
AC612_05350	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AC612_05360	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AC612_05365	ENOG4107RZZ	dna polymerase iii epsilon subunit
AC612_05370	ENOG4108ZF3	Phosphatase
AC612_05385	ENOG4105DKP	glycosyl transferase, family 9
AC612_05390	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
AC612_05395	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
AC612_05400	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AC612_05410	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AC612_05415	ENOG4105M00	molybdopterin converting factor, subunit 1
AC612_05420	ENOG4108ZAF	Molybdopterin
AC612_05455	ENOG4105D5G	Transposase
AC612_05460	ENOG4105F2I	Transposase
AC612_05470	ENOG4105D5G	Transposase
AC612_05485	ENOG4107QMP	dna polymerase iii subunits gamma and tau
AC612_05490	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
AC612_05495	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
AC612_05500	ENOG4105K59	histidine triad (HIT) protein
AC612_05510	ENOG4105F8C	transglutaminase domain-containing protein
AC612_05520	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AC612_05530	ENOG41089I4	Inherit from COG: Glycosyl transferase, family 2
AC612_05540	ENOG4108UHJ	MAF-like protein
AC612_05545	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
AC612_05550	ENOG4105VGS	50s ribosomal protein l32
AC612_05555	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AC612_05565	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
AC612_05570	ENOG4105CHR	reductase
AC612_05575	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AC612_05580	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AC612_05590	ENOG4105HHA	aminodeoxychorismate lyase
AC612_05595	ENOG4107QRG	dna polymerase iii
AC612_05615	ENOG4108JU7	Transcriptional regulator
AC612_05620	ENOG4105CR4	methylisocitrate lyase
AC612_05625	ENOG4105BZN	citrate synthase
AC612_05630	ENOG4108I0Z	Aconitate hydratase
AC612_05635	ENOG4105C7F	AcnD-accessory protein PrpF
AC612_05650	ENOG4105DN3	alpha-2-macroglobulin domain protein
AC612_05665	ENOG4108JQB	penicillin-binding protein 1C
AC612_05690	ENOG4105M3Z	response regulator
AC612_05695	ENOG4107QJR	hflk protein
AC612_05700	ENOG4105EPW	hflc protein
AC612_05710	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
AC612_05725	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
AC612_05730	ENOG4108XFH	Transcriptional regulator
AC612_05740	ENOG4105D5G	Transposase
AC612_05745	ENOG4105CVR	type I restriction-modification system
AC612_05750	ENOG41062MS	nucleotidyltransferase substrate binding protein
AC612_05760	ENOG4105F2I	Transposase
AC612_05765	ENOG4105EKX	Restriction modification system DNA (Specificity
AC612_05780	ENOG4105F2I	Transposase
AC612_05785	ENOG4105DZR	Type I site-specific deoxyribonuclease
AC612_05810	ENOG4105CVJ	phosphoglycerate mutase
AC612_05815	ENOG4107Z4K	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
AC612_05825	ENOG4105BZP	glycoside hydrolase 15-related
AC612_05830	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
AC612_05835	ENOG4105D5G	Transposase
AC612_05840	ENOG4105CWX	Alpha-1,2-mannosidase
AC612_05845	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
AC612_05860	ENOG4105C3M	thioredoxin reductase
AC612_05890	ENOG4105C7W	Xanthine dehydrogenase
AC612_05895	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
AC612_05900	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
AC612_05935	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
AC612_05955	ENOG4105C0B	DNA polymerase III (alpha subunit)
AC612_05970	ENOG4105EPD	Oligopeptide transporter, Opt family
AC612_05985	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
AC612_06000	ENOG4106AXJ	AraC family transcriptional regulator
AC612_06025	ENOG4105CV8	reductase
AC612_06030	ENOG4105EBR	Carboxylesterase
AC612_06035	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AC612_06040	ENOG4105C2C	drug resistance transporter, Bcr CflA
AC612_06055	ENOG4105DIJ	Phosphoethanolamine transferase
AC612_06070	ENOG4105ETX	regulatoR
AC612_06075	ENOG4105DHQ	Histidine kinase
AC612_06085	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
AC612_06090	ENOG4107QMS	site-determining protein
AC612_06095	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
AC612_06105	ENOG4105BZU	Histidine kinase
AC612_06110	ENOG4105WH1	Two component transcriptional regulator luxr family
AC612_06150	ENOG4107SPG	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
AC612_06160	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
AC612_06180	ENOG4105C29	acyl-CoA thioesterase
AC612_06195	ENOG4108TGP	Thioesterase superfamily protein
AC612_06200	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AC612_06205	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
AC612_06210	ENOG4105K46	50S ribosomal protein l27
AC612_06215	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AC612_06220	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
AC612_06225	ENOG4105CJR	Integral membrane protein (MviN
AC612_06230	ENOG4105DTN	riboflavin biosynthesis protein ribF
AC612_06235	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
AC612_06240	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
AC612_06245	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
AC612_06275	ENOG4105D5G	Transposase
AC612_06290	ENOG4105E2S	oxidase) subunit II
AC612_06295	ENOG4105BZ9	Cytochrome C oxidase, subunit I
AC612_06300	ENOG4105CCU	oxidase (Subunit III)
AC612_06305	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
AC612_06315	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
AC612_06325	ENOG4105D5G	Transposase
AC612_06330	ENOG4105D5G	Transposase
AC612_06335	ENOG4105KAF	membrAne
AC612_06350	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
AC612_06360	ENOG4107MMM	Anti-sigma-factor antagonist
AC612_06365	ENOG4105FUA	antagonist
AC612_06370	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
AC612_06380	ENOG4105BZU	Histidine kinase
AC612_06405	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
AC612_06415	ENOG4105C08	Histidine kinase
AC612_06420	ENOG4107Z5C	methylesterase
AC612_06425	ENOG4105BZU	Histidine kinase
AC612_06430	ENOG4105BZU	Histidine kinase
AC612_06450	ENOG4105D5G	Transposase
AC612_06455	ENOG4105F2I	Transposase
AC612_06465	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
AC612_06475	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
AC612_06480	ENOG4105VEJ	Heat shock protein
AC612_06500	ENOG4107QJQ	Mate efflux family protein
AC612_06505	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
AC612_06510	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
AC612_06515	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
AC612_06520	ENOG4105K5M	30s ribosomal protein S16
AC612_06530	ENOG4107QWG	2-Nitropropane dioxygenase
AC612_06540	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AC612_06545	ENOG4105CRE	cytochrome C
AC612_06550	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
AC612_06560	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
AC612_06570	ENOG4105D5G	Transposase
AC612_06590	ENOG4105CNT	hydrolase family 2
AC612_06595	ENOG4106FKC	arabinogalactan endo-1,4-beta-galactosidase
AC612_06610	ENOG4105C26	Dehydrogenase
AC612_06615	ENOG4105C1G	acyl-Coa dehydrogenase
AC612_06620	ENOG4105E39	Enoyl-CoA hydratase
AC612_06625	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AC612_06630	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
AC612_06655	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
AC612_06660	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
AC612_06665	ENOG4105D7Q	type ii secretion system
AC612_06685	ENOG4107QHF	type ii secretion system protein e
AC612_06690	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AC612_06700	ENOG4107TUY	Histidine kinase
AC612_06705	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
AC612_06710	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
AC612_06715	ENOG4105D5G	Transposase
AC612_06725	ENOG4105C4K	Nad synthetase
AC612_06735	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AC612_06740	ENOG4105C34	Pseudouridine synthase
AC612_06755	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
AC612_06760	ENOG4105C8Q	Methyl-accepting chemotaxis
AC612_06765	ENOG4105DZG	Dehydrogenase
AC612_06770	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
AC612_06775	ENOG4105BZP	glycoside hydrolase 15-related
AC612_06780	ENOG4108K4C	ec 3.1.3.12
AC612_06785	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AC612_06820	ENOG41082IR	Excinuclease ABC C subunit domain protein
AC612_06825	ENOG4107ZSV	Receptor
AC612_06830	ENOG4105CPU	Monooxygenase
AC612_06835	ENOG4105CPC	Aldo Keto reductase
AC612_06840	ENOG4105GVF	(ABC) transporter
AC612_06845	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
AC612_06850	ENOG4105E2Y	ABC, transporter
AC612_06855	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AC612_06865	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AC612_06885	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
AC612_06890	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
AC612_06900	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
AC612_06905	ENOG4108YZT	Adenosylcobinamide kinase
AC612_06910	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
AC612_06935	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
AC612_06945	ENOG4105C6X	Major Facilitator
AC612_06960	ENOG4105GAV	receptor
AC612_06970	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
AC612_06980	ENOG4107RNH	Outer membrane receptor FepA
AC612_06985	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AC612_06995	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AC612_07000	ENOG4105C5H	ABC transporter
AC612_07010	ENOG4105ETT	transcriptional Regulator, LysR family
AC612_07025	ENOG4105HSS	phospholipase C
AC612_07035	ENOG4108ISG	Major Facilitator
AC612_07050	ENOG4105C9M	aspartyl-trna synthetase
AC612_07065	ENOG4105CDY	transcriptional regulatory protein
AC612_07070	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
AC612_07075	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
AC612_07080	ENOG4105DFH	Transport of potassium into the cell (By similarity)
AC612_07085	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
AC612_07090	ENOG4107YD3	Thioesterase
AC612_07095	ENOG4105E02	MotA TolQ exbB proton channel
AC612_07110	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
AC612_07115	ENOG4105KCK	Peptidoglycan-associated lipoprotein
AC612_07125	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
AC612_07140	ENOG410903D	sensor protein
AC612_07160	ENOG4105C8Q	Methyl-accepting chemotaxis
AC612_07205	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AC612_07215	ENOG4105CQ7	ATP-dependent helicase
AC612_07225	ENOG4105CHC	glucokinase (EC 2.7.1.2)
AC612_07240	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
AC612_07245	ENOG4105Z85	coenzyme PQQ synthesis
AC612_07250	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
AC612_07255	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
AC612_07260	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AC612_07275	ENOG4105BZ4	penicillin-binding protein
AC612_07285	ENOG4105DVT	helicase
AC612_07290	ENOG41072GX	Peptidase M22 Glycoprotease
AC612_07295	ENOG41065RQ	ADP-ribosylation crystallin J1
AC612_07305	ENOG4105D7Z	glutathione synthase
AC612_07310	ENOG4108UNF	response regulator
AC612_07315	ENOG4105M3Z	response regulator
AC612_07320	ENOG410807Z	Modulation of CheA activity in response to attractants (Chemotaxis
AC612_07325	ENOG4105C8Q	Methyl-accepting chemotaxis
AC612_07330	ENOG4105CBS	Chea signal transduction histidine kinase
AC612_07345	ENOG4105D9U	N-acetyltransferase
AC612_07360	ENOG4106N3A	copper homeostasis protein cutc
AC612_07400	ENOG4105CWX	Alpha-1,2-mannosidase
AC612_07410	ENOG4105F8D	glycoside hydrolase family 4
AC612_07420	ENOG4107QTZ	amino acid
AC612_07455	ENOG4105E2D	ec 3.2.1.52
AC612_07460	ENOG4105VRS	hydrolase family 18
AC612_07475	ENOG4105CHC	glucokinase (EC 2.7.1.2)
AC612_07480	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
AC612_07490	ENOG4107RK2	ADP-ribose diphosphatase NudE
AC612_07495	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
AC612_07500	ENOG4105DXN	mazG family
AC612_07505	ENOG4105KK4	UPF0060 membrane protein
AC612_07515	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
AC612_07520	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
AC612_07540	ENOG4105D5G	Transposase
AC612_07565	ENOG4107QPN	acyl-Coa dehydrogenase
AC612_07575	ENOG4108IG5	Transcriptional regulator
AC612_07580	ENOG4105F2I	Transposase
AC612_07585	ENOG4105F2I	Transposase
AC612_07590	ENOG4105D5G	Transposase
AC612_07595	ENOG4105D05	Receptor
AC612_07605	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
AC612_07610	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
AC612_07620	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AC612_07625	ENOG41066T0	asmA family
AC612_07630	ENOG4108UT2	hemolysin iii
AC612_07635	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
AC612_07640	ENOG4105DR5	peptidase
AC612_07645	ENOG4106TYC	homoserine o-acetyltransferase (EC 2.3.1.31)
AC612_07650	ENOG4105C28	cystathionine
AC612_07655	ENOG4105CFH	Aspartokinase
AC612_07665	ENOG4105EJQ	L-serine dehydratase
AC612_07685	ENOG4108YYC	ycei family
AC612_07690	ENOG4105BZU	Histidine kinase
AC612_07700	ENOG4105BZU	Histidine kinase
AC612_07705	ENOG4105BZU	Histidine kinase
AC612_07710	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AC612_07715	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
AC612_07725	ENOG4105D49	3-dehydroquinate synthase
AC612_07730	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
AC612_07735	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
AC612_07745	ENOG4108P9J	Phage shock protein A
AC612_07770	ENOG4106032	Glutathionylspermidine synthase
AC612_07780	ENOG4108Z4X	TRANSCRIPTIONal
AC612_07835	ENOG4105CUB	amino acid
AC612_07860	ENOG4105D5G	Transposase
AC612_07865	ENOG4105C85	amino acid
AC612_07875	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AC612_07880	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AC612_07885	ENOG4107UWA	esterase
AC612_07890	ENOG4105CJW	magnesium transporter
AC612_07895	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
AC612_07900	ENOG41080Z8	PHOSPHOCARRIER protein
AC612_07910	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
AC612_07915	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
AC612_07920	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
AC612_07925	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
AC612_07930	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AC612_07935	ENOG4108IUZ	ABC transporter
AC612_07940	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
AC612_07950	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
AC612_07955	ENOG4105C2X	Arabinose 5-phosphate isomerase
AC612_07965	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
AC612_07985	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
AC612_07995	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
AC612_08005	ENOG4105C02	permease
AC612_08015	ENOG4108S0S	Nucleotidyl transferase
AC612_08020	ENOG4105EHM	Aminoglycoside phosphotransferase
AC612_08035	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
AC612_08045	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
AC612_08050	ENOG4105CJ2	(LipO)protein
AC612_08075	ENOG4107E2E	PKHD-type hydroxylase
AC612_08080	ENOG4108IU3	tonb-dependent siderophore receptor
AC612_08095	ENOG4105C9B	Cysteine desulfurase
AC612_08100	ENOG4105JRK	feS assembly protein SufD
AC612_08105	ENOG4105C3K	feS assembly ATPase SufC
AC612_08125	ENOG4108Z0Z	intracellular protease Pfpi family
AC612_08145	ENOG4105FAA	peptidase M23
AC612_08155	ENOG4105II7	pyrroline-5-carboxylate reductase
AC612_08160	ENOG4105DFA	alanine racemase domain protein
AC612_08165	ENOG4105CZX	twitching motility protein
AC612_08170	ENOG4105CZX	twitching motility protein
AC612_08185	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AC612_08195	ENOG4108UJU	UPF0301 protein
AC612_08200	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
AC612_08205	ENOG4105CXT	aspartate transcarbamylase
AC612_08210	ENOG4108Z9K	Osmotically inducible protein
AC612_08220	ENOG4105JAB	phenazine biosynthesis protein, phzf family
AC612_08225	ENOG4105JAB	phenazine biosynthesis protein, phzf family
AC612_08230	ENOG4105CFH	Aspartokinase
AC612_08245	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
AC612_08255	ENOG4105EAH	synthase
AC612_08260	ENOG4108UUM	single-stranded DNA-binding protein
AC612_08275	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
AC612_08280	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
AC612_08285	ENOG4105C7W	Xanthine dehydrogenase
AC612_08290	ENOG4107XAN	XdhC and CoxI family
AC612_08340	ENOG4105VCD	cytoplasmic protein
AC612_08345	ENOG4105D22	carbon starvation protein
AC612_08350	ENOG4105EUB	pirin domain protein
AC612_08365	ENOG4105EUB	pirin domain protein
AC612_08370	ENOG4105D5G	Transposase
AC612_08380	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
AC612_08385	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AC612_08395	ENOG4105C9K	Endothelin-converting enzyme 1
AC612_08400	ENOG4107RZC	phospholipase d
AC612_08405	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AC612_08410	ENOG4105BZU	Histidine kinase
AC612_08415	ENOG4105BZU	Histidine kinase
AC612_08420	ENOG4108V3W	Chemotaxis protein, CheW
AC612_08425	ENOG4105C8Q	Methyl-accepting chemotaxis
AC612_08430	ENOG4105CBS	Chea signal transduction histidine kinase
AC612_08440	ENOG4108JA2	transcriptioN-repair coupling factor
AC612_08450	ENOG4105D6S	protein involved in catabolism of external DNA
AC612_08455	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
AC612_08460	ENOG4105EB3	Histidine kinase
AC612_08475	ENOG4105CT7	inner membrane cred family protein
AC612_08500	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AC612_08505	ENOG4105MYN	Zinc uptake regulation protein
AC612_08515	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AC612_08520	ENOG4105BZS	acriflavin resistance protein
AC612_08525	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
AC612_08530	ENOG4108JGH	Tetr family transcriptional regulator
AC612_08540	ENOG4105CF7	AraC family transcriptional regulator
AC612_08550	ENOG4105CC0	LysR family Transcriptional regulator
AC612_08555	ENOG4105F27	Major Facilitator
AC612_08560	ENOG4108FN7	Aldo keto reductase
AC612_08580	ENOG4105UGU	tonB-dependent Receptor
AC612_08655	ENOG4105EMN	RNA polymerase sigma factor
AC612_08665	ENOG4105BZU	Histidine kinase
AC612_08670	ENOG4105FE9	pseudouridine synthase
AC612_08675	ENOG4105BZU	Histidine kinase
AC612_08695	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
AC612_08700	ENOG4105FQP	Beta-lactamase
AC612_08710	ENOG4105BZU	Histidine kinase
AC612_08715	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AC612_08720	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
AC612_08745	ENOG4105BZ1	(ABC) transporter
AC612_08785	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
AC612_08790	ENOG4105WG9	Conserved Protein
AC612_08805	ENOG4105D5G	Transposase
AC612_08830	ENOG4107QR8	Thioredoxin
AC612_08840	ENOG4105C8T	Leucyl-tRNA synthetase
AC612_08855	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
AC612_08870	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
AC612_08885	ENOG4105MPN	Membrane
AC612_08890	ENOG4108Z03	MAF-like protein
AC612_08895	ENOG4105C03	ribonuclease
AC612_08900	ENOG4105QD6	exported protein
AC612_08910	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
AC612_08915	ENOG4105N42	UPF0307 protein
AC612_08920	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
AC612_08935	ENOG4105CTB	Polyprenyl synthetase
AC612_08940	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AC612_08945	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
AC612_08950	ENOG4105G6Z	alkaline phosphatase
AC612_08955	ENOG4105CK2	sodium dicarboxylate symporter
AC612_08960	ENOG41082K6	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
AC612_08970	ENOG4105K4H	Nlp p60 protein
AC612_08975	ENOG4105K4H	Nlp p60 protein
AC612_08980	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
AC612_08990	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
AC612_08995	ENOG4105DC8	reductase
AC612_09015	ENOG4105C9K	Endothelin-converting enzyme 1
AC612_09020	ENOG4105C9K	Endothelin-converting enzyme 1
AC612_09030	ENOG4105F2I	Transposase
AC612_09050	ENOG4105DHP	deoxycytidine triphosphate deaminase
AC612_09090	ENOG4105NI8	Cytosine-specific methyltransferase
AC612_09095	ENOG4105D5G	Transposase
AC612_09100	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
AC612_09105	ENOG4108RRZ	Transcription elongation factor GreB
AC612_09120	ENOG4107VIJ	nudix hydrolase
AC612_09125	ENOG4105D7A	ATP-binding protein
AC612_09135	ENOG4105DJ4	phosphatidylserine decarboxylase
AC612_09145	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
AC612_09150	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
AC612_09155	ENOG4105C5I	Dehydrogenase
AC612_09160	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
AC612_09180	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
AC612_09185	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
AC612_09195	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
AC612_09205	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
AC612_09210	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
AC612_09215	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AC612_09235	ENOG4105BZU	Histidine kinase
AC612_09250	ENOG4107FW0	short-chain dehydrogenase reductase
AC612_09255	ENOG4105CP7	Triose-phosphate isomerase
AC612_09270	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AC612_09275	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AC612_09280	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AC612_09285	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AC612_09290	ENOG4105GKE	subunit e
AC612_09295	ENOG4107QIZ	NADH dehydrogenase
AC612_09300	ENOG4107R0R	NADH dehydrogenase subunit g
AC612_09305	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
AC612_09310	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AC612_09315	ENOG4105DF2	NADH dehydrogenase subunit j
AC612_09325	ENOG4105D65	subunit l
AC612_09330	ENOG4105C8S	subunit m
AC612_09335	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AC612_09345	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
AC612_09350	ENOG4105CHV	Transcription elongation factor NusA
AC612_09355	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
AC612_09360	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
AC612_09365	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
AC612_09370	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
AC612_09375	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AC612_09385	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
AC612_09395	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
AC612_09400	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
AC612_09405	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AC612_09410	ENOG4105M2J	Glutaredoxin
AC612_09420	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
AC612_09425	ENOG4108KPZ	tonB-dependent Receptor
AC612_09430	ENOG4105EWT	decarboxylase family
AC612_09480	ENOG4105D5G	Transposase
AC612_09490	ENOG4105D5G	Transposase
AC612_09495	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
AC612_09530	ENOG4105CMA	conjugation trbi family protein
AC612_09590	ENOG4105D5G	Transposase
AC612_09600	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
AC612_09605	ENOG4106H78	methyltransferase
AC612_09610	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
AC612_09620	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
AC612_09625	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
AC612_09635	ENOG4105E08	Glycoside hydrolase, family 9
AC612_09640	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
AC612_09680	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
AC612_09685	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
AC612_09690	ENOG4105VIE	preprotein translocase, subunit YajC
AC612_09695	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AC612_09700	ENOG4107QT7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AC612_09705	ENOG4105D5G	Transposase
AC612_09715	ENOG4105D5G	Transposase
AC612_09725	ENOG4105DM4	PTS System
AC612_09730	ENOG4105DE4	1-phosphofructokinase
AC612_09735	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
AC612_09740	ENOG4108M60	Transcriptional regulator
AC612_09745	ENOG4105BZS	acriflavin resistance protein
AC612_09750	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AC612_09760	ENOG4105C7I	Dehydrogenase
AC612_09780	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AC612_09790	ENOG4105E1F	short-chain dehydrogenase reductase
AC612_09810	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AC612_09815	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AC612_09820	ENOG4105BZU	Histidine kinase
AC612_09825	ENOG4106BRA	Membrane
AC612_09840	ENOG4105FCD	Major Facilitator
AC612_09850	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
AC612_09860	ENOG4105CSH	Transporter
AC612_09865	ENOG4105W3S	hemerythrin-like, metal-binding protein
AC612_09870	ENOG4105BZU	Histidine kinase
AC612_09875	ENOG4105CJP	fad dependent oxidoreductase
AC612_09880	ENOG4105CFQ	glutamine synthetase
AC612_09895	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
AC612_09900	ENOG4107RUE	extracellular solute-binding protein family 1
AC612_09925	ENOG4105F38	ABC transporter, permease
AC612_09930	ENOG4105D38	putrescine abc transporter
AC612_09955	ENOG4108JU5	Magnesium and cobalt efflux protein
AC612_09965	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
AC612_09975	ENOG4105C9A	Phoh family
AC612_09980	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
AC612_09995	ENOG4105E4C	Lytic transglycosylase catalytic
AC612_10000	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AC612_10005	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AC612_10010	ENOG4105EIX	cytochrome c1
AC612_10015	ENOG4107MKT	Stringent starvation protein a
AC612_10020	ENOG4105KB2	stringent starvation protein b
AC612_10035	ENOG4107QRT	dEAD DEAH box helicase
AC612_10040	ENOG4108VX5	3-methyladenine DNA glycosylase
AC612_10045	ENOG4105C8Q	Methyl-accepting chemotaxis
AC612_10050	ENOG4108V3W	Chemotaxis protein, CheW
AC612_10080	ENOG4105DQE	DNA ligase
AC612_10090	ENOG4105E6M	Sulphatase-modifying factor protein
AC612_10100	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AC612_10105	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
AC612_10110	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
AC612_10115	ENOG4105K8N	protein family UPF0079, ATPase
AC612_10120	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
AC612_10125	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
AC612_10145	ENOG4105CHR	reductase
AC612_10150	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
AC612_10155	ENOG4105D0M	Protease HtpX homolog
AC612_10160	ENOG4105F2I	Transposase
AC612_10170	ENOG4105CBX	hi0933 family
AC612_10175	ENOG4108VWS	Yaeq family
AC612_10180	ENOG4105VEQ	Cold shock protein
AC612_10185	ENOG4108RXX	maleylacetoacetate isomerase
AC612_10195	ENOG4105CNG	UPF0061 protein
AC612_10200	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
AC612_10205	ENOG4105C1J	atp-dependent rna helicase
AC612_10210	ENOG4105C5H	ABC transporter
AC612_10225	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AC612_10230	ENOG4105ECY	inositol monophosphatase
AC612_10245	ENOG4105BZU	Histidine kinase
AC612_10250	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
AC612_10255	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AC612_10265	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AC612_10270	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
AC612_10275	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AC612_10320	ENOG4107FQ9	ethanolamine ammonia-lyase
AC612_10325	ENOG4105CPD	ethanolamine ammonia-lyase
AC612_10340	ENOG4105CD3	dihydroorotase
AC612_10345	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
AC612_10355	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AC612_10365	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
AC612_10370	ENOG4105C8N	cysteinyl-tRNA synthetase
AC612_10380	ENOG4105DBV	ornithine carbamoyltransferase
AC612_10385	ENOG4105CDH	Citrulline--aspartate ligase
AC612_10400	ENOG4105CAS	nag kinase
AC612_10410	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
AC612_10415	ENOG4105CH7	arginosuccinase
AC612_10425	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
AC612_10430	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
AC612_10540	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AC612_10545	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AC612_10550	ENOG4108JJ9	ABC, transporter
AC612_10555	ENOG4108JJ8	(ABC) transporter
AC612_10565	ENOG4105DWV	Homoserine O-trans-acetylase
AC612_10570	ENOG4108M1T	Cytochrome c-type biogenesis protein
AC612_10575	ENOG4105KWW	Biogenesis protein
AC612_10585	ENOG4105DA4	cytochrome c-type biogenesis protein
AC612_10590	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
AC612_10600	ENOG41060IM	Heme exporter protein
AC612_10605	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
AC612_10610	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
AC612_10615	ENOG4105CHM	Aminotransferase
AC612_10620	ENOG4105CZ7	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
AC612_10635	ENOG4105FE9	pseudouridine synthase
AC612_10640	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
AC612_10645	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
AC612_10650	ENOG4105K9H	YciI-like protein
AC612_10680	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
AC612_10685	ENOG4105DRS	transport system, permease
AC612_10715	ENOG4105DWY	Agmatine deiminase
AC612_10725	ENOG4105YK5	50S ribosomal protein L36
AC612_10730	ENOG4105CAT	Cytidine monophosphate kinase
AC612_10735	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
AC612_10740	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AC612_10750	ENOG4105CFV	Tetratricopeptide repeat protein
AC612_10755	ENOG4105ESV	Glycosyl transferase, family 4
AC612_10765	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
AC612_10770	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
AC612_10780	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
AC612_10785	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AC612_10790	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AC612_10800	ENOG4105D5G	Transposase
AC612_10840	ENOG4105WH1	Two component transcriptional regulator luxr family
AC612_10855	ENOG4105CHJ	isochorismatase hydrolase
AC612_10870	ENOG4107SFI	Major Facilitator superfamily
AC612_10885	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AC612_10900	ENOG4108N8X	transition metal ion binding
AC612_10930	ENOG4108ZXC	Two component transcriptional regulator, luxr family
AC612_10965	ENOG4108HRK	Histidine kinase
AC612_10970	ENOG4105DY9	regulatoR
AC612_11010	ENOG410903D	sensor protein
AC612_11030	ENOG4105E18	UPF0276 protein
AC612_11045	ENOG4108RCM	Nitroreductase
AC612_11060	ENOG4105F2I	Transposase
AC612_11115	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AC612_11135	ENOG4108MH3	Polyketide beta-ketoacyl acyl carrier protein synthase
AC612_11140	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AC612_11255	ENOG4105YPM	F pilin acetylation protein TraX
AC612_11275	ENOG4105YPM	F pilin acetylation protein TraX
AC612_11315	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
AC612_11320	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
AC612_11370	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
AC612_11375	ENOG41090A4	Pterin carbinolamine dehydratase
AC612_11385	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
AC612_11390	ENOG4105F2I	Transposase
AC612_11395	ENOG4108NST	exported protein
AC612_11400	ENOG4105EI2	Pseudouridine synthase
AC612_11405	ENOG4105C03	ribonuclease
AC612_11415	ENOG4105C72	UPF0176 protein
AC612_11425	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AC612_11435	ENOG4107QQG	Dehydrogenase
AC612_11460	ENOG4105D5G	Transposase
AC612_11475	ENOG4105CMM	transposase
AC612_11485	ENOG4105ECI	YeeC-like protein
AC612_11490	ENOG4105F6A	helicase
AC612_11500	ENOG4105D5G	Transposase
AC612_11530	ENOG4107QJE	Chromosome Partitioning Protein
AC612_11565	ENOG4107YH6	single-stranded DNA-binding protein
AC612_11570	ENOG4108IYH	Dna topoisomerase
AC612_11590	ENOG4105C8Y	Acetylornithine aminotransferase
AC612_11605	ENOG4105CVE	Lytic murein transglycosylase
AC612_11615	ENOG4105F2I	Transposase
AC612_11620	ENOG4105D5G	Transposase
AC612_11815	ENOG4106NZI	LysR family Transcriptional regulator
AC612_11935	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AC612_12040	ENOG4105CS6	Rhs element vgr protein
AC612_12105	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
AC612_12110	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
AC612_12125	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
AC612_12130	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
AC612_12135	ENOG4105BZ1	(ABC) transporter
AC612_12140	ENOG4105M15	transport protein ExbD
AC612_12150	ENOG4108EC8	DNA internalization-related competence protein ComEC
AC612_12160	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AC612_12165	ENOG4105D60	lipoprotein releasing system transmembrane protein
AC612_12175	ENOG410681N	tpr repeat protein
AC612_12200	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
AC612_12205	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
AC612_12220	ENOG4105CHC	glucokinase (EC 2.7.1.2)
AC612_12225	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
AC612_12230	ENOG4105C01	Dihydroxy-acid dehydratase
AC612_12235	ENOG4108UHU	Aldolase
AC612_12260	ENOG4105N7H	Cytochrome
AC612_12305	ENOG4105BZU	Histidine kinase
AC612_12310	ENOG4105BZM	domain protein
AC612_12335	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
AC612_12345	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
AC612_12365	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
AC612_12380	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
AC612_12385	ENOG4108Z6B	deaminase
AC612_12390	ENOG4105KST	dependent repressor
AC612_12395	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
AC612_12425	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
AC612_12430	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AC612_12440	ENOG4105CGK	Exodeoxyribonuclease III
AC612_12475	ENOG4105D06	uba thif-type nad fad binding protein
AC612_12480	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AC612_12485	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AC612_12490	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
AC612_12500	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
AC612_12510	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
AC612_12515	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
AC612_12530	ENOG4105CHU	acetyl-coa acetyltransferase
AC612_12535	ENOG41082MI	Protein CrcB homolog
AC612_12540	ENOG4105D1H	recombination factor protein RarA
AC612_12550	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
AC612_12560	ENOG4105CNU	cell division protein FtsK
AC612_12565	ENOG4105C3M	thioredoxin reductase
AC612_12575	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
AC612_12580	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
AC612_12585	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AC612_12590	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
AC612_12600	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
AC612_12620	ENOG4105BZU	Histidine kinase
AC612_12630	ENOG4105BZU	Histidine kinase
AC612_12635	ENOG4105BZU	Histidine kinase
AC612_12655	ENOG4107R88	Chemotaxis protein (CheV)
AC612_12665	ENOG4108ZC9	flagellar basal-body rod protein flgc
AC612_12670	ENOG410822I	Flagellar hook capping protein
AC612_12675	ENOG4105BZE	flagellar hook protein, FlgE
AC612_12680	ENOG4108KPB	Flagellar basal-body rod protein FlgF
AC612_12685	ENOG4105CGA	flagellar basal-body rod protein FlgG
AC612_12690	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
AC612_12695	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
AC612_12700	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
AC612_12710	ENOG4105DTJ	flagellar hook-associated protein
AC612_12715	ENOG4105F2I	Transposase
AC612_12725	ENOG4107W9T	flagellar hook-associated
AC612_12730	ENOG4105MQ3	flagellar protein FliS
AC612_12750	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AC612_12755	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AC612_12760	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AC612_12775	ENOG4108P1X	synthase
AC612_12780	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
AC612_12785	ENOG4105CHR	reductase
AC612_12815	ENOG4105F2I	Transposase
AC612_12825	ENOG4108KU3	Integrase
AC612_12835	ENOG4105QNF	Outer membrane lipoprotein
AC612_12845	ENOG4105CSU	acyl-Coa dehydrogenase
AC612_12855	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
AC612_12875	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
AC612_12880	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AC612_12885	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AC612_12910	ENOG4108NQK	Catalyzes the transfer of a glucuronic acid (GlcA) residue from UDP-glucuronate to mannose-alpha-1,3-glucose-beta- 1,4-glucose-P-P-polyisoprenyl to form the lipid-linked tetrasaccharide GlcA-Man-Glc(2)-PP-Pol, with a glucuronic acid- beta-mannose linkage. Is involved in the biosynthesis of the exopolysaccharide xanthan, since it catalyzes the fourth glycosylation step in the assembly of the pentasaccharide-P-P- polyisoprenyl repeating unit of xanthan. Is unable to use the trisaccharide acceptor freed from the pyrophosphate lipid moiety. Does not show specificity for the lipidic portion of the acceptor. Shows diminished activity when tested with 6-O-acetyl-mannose- alpha-1,3-glucose-beta-1,4-glucose-P-P-polyisoprenyl, a
AC612_12920	ENOG4107Y2G	Glycosyl transferase (Group 1
AC612_12945	ENOG4105D3Q	Sugar transferase
AC612_12965	ENOG4105WJX	transcriptional regulator MERR family
AC612_12970	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AC612_12975	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
AC612_12980	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
AC612_12985	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
AC612_12990	ENOG41082NX	50s ribosomal protein l35
AC612_12995	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
AC612_13000	ENOG4105C22	threonyL-tRNA synthetase
AC612_13005	ENOG4105ETE	Transcriptional regulator (LacI family
AC612_13015	ENOG4107RBJ	symporter
AC612_13045	ENOG4105F2I	Transposase
AC612_13050	ENOG4105F2I	Transposase
AC612_13070	ENOG4105CG3	alpha amylase, catalytic region
AC612_13085	ENOG4105F2I	Transposase
AC612_13170	ENOG4107QTZ	amino acid
AC612_13185	ENOG4105DC7	peptidase M24
AC612_13195	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AC612_13210	ENOG41080HI	glycine oxidase
AC612_13215	ENOG4105CTU	Proline racemase
AC612_13225	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AC612_13230	ENOG4105CEN	a g-specific adenine glycosylase
AC612_13235	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
AC612_13240	ENOG4105BZU	Histidine kinase
AC612_13275	ENOG4105F2I	Transposase
AC612_13290	ENOG4105F2I	Transposase
AC612_13305	ENOG4107RGC	Glycosyl transferase, family 2
AC612_13310	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
AC612_13315	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
AC612_13320	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
AC612_13330	ENOG4108JIR	Flagellum-specific ATP synthase
AC612_13350	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
AC612_13355	ENOG4105DD5	Flagellar motor switch protein
AC612_13360	ENOG4105K0P	flagellar biosynthesis protein
AC612_13365	ENOG4105CN7	Flagellar biosynthetic protein FliP
AC612_13370	ENOG4105VS8	Flagellar biosynthetic protein fliq
AC612_13375	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
AC612_13390	ENOG4105BZU	Histidine kinase
AC612_13400	ENOG4105D00	flagellar biosynthetic protein flhB
AC612_13405	ENOG4105D7B	Flagellar biosynthesis protein flha
AC612_13410	ENOG4105FZW	flagellar biosynthesis regulator FlhF
AC612_13415	ENOG4107R21	site-determining protein
AC612_13420	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AC612_13425	ENOG4108VYJ	response regulator receiver protein
AC612_13435	ENOG4105CBS	Chea signal transduction histidine kinase
AC612_13465	ENOG4105F2I	Transposase
AC612_13490	ENOG4105D5G	Transposase
AC612_13505	ENOG4105E14	MotA TolQ exbB proton channel
AC612_13510	ENOG4105ER2	Ompa motb domain protein
AC612_13515	ENOG4107QJE	Chromosome Partitioning Protein
AC612_13520	ENOG4108V3W	Chemotaxis protein, CheW
AC612_13530	ENOG4108VYJ	response regulator receiver protein
AC612_13535	ENOG4105CBS	Chea signal transduction histidine kinase
AC612_13540	ENOG4105C8Q	Methyl-accepting chemotaxis
AC612_13550	ENOG4105C8Q	Methyl-accepting chemotaxis
AC612_13550	ENOG4105C8Q	Methyl-accepting chemotaxis
AC612_13555	ENOG4105C8Q	Methyl-accepting chemotaxis
AC612_13565	ENOG4105C8Q	Methyl-accepting chemotaxis
AC612_13575	ENOG4105C8Q	Methyl-accepting chemotaxis
AC612_13585	ENOG4105C8Q	Methyl-accepting chemotaxis
AC612_13590	ENOG4105C8Q	Methyl-accepting chemotaxis
AC612_13595	ENOG4105C8Q	Methyl-accepting chemotaxis
AC612_13600	ENOG4105C8Q	Methyl-accepting chemotaxis
AC612_13615	ENOG4108V3W	Chemotaxis protein, CheW
AC612_13625	ENOG4105C8Q	Methyl-accepting chemotaxis
AC612_13630	ENOG4105BZU	Histidine kinase
AC612_13635	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
AC612_13640	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AC612_13645	ENOG4105BZU	Histidine kinase
AC612_13650	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
AC612_13655	ENOG4107QIJ	Aconitate hydratase 2
AC612_13670	ENOG4107QM5	aconitate hydratase
AC612_13685	ENOG4105CEY	Amp-dependent synthetase and ligase
AC612_13690	ENOG4105E39	Enoyl-CoA hydratase
AC612_13695	ENOG4105BZU	Histidine kinase
AC612_13700	ENOG4105BZU	Histidine kinase
AC612_13705	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AC612_13710	ENOG4105CRK	lysyL-tRNA synthetase
AC612_13715	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
AC612_13720	ENOG4105DY9	regulatoR
AC612_13730	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
AC612_13740	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
AC612_13745	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AC612_13755	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
AC612_13760	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
AC612_13765	ENOG4108RPX	mosc domain containing protein
AC612_13770	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AC612_13785	ENOG4105CE1	Ferrous iron transport protein b
AC612_13805	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
AC612_13815	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AC612_13835	ENOG4105CQB	FAD linked oxidase domain protein
AC612_13840	ENOG4108JQ1	Dehydrogenase
AC612_13850	ENOG4105CUB	amino acid
AC612_13855	ENOG4105CUB	amino acid
AC612_13860	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
AC612_13865	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
AC612_13870	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
AC612_13885	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
AC612_13890	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
AC612_13895	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
AC612_13900	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
AC612_13905	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
AC612_13910	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AC612_13915	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
AC612_13920	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
AC612_13930	ENOG4105CUT	histidyl-tRNA synthetase
AC612_13935	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
AC612_13965	ENOG4108606	TspO/MBR family
AC612_13975	ENOG4105D5G	Transposase
AC612_13985	ENOG4105F2I	Transposase
AC612_14000	ENOG4105D5G	Transposase
AC612_14030	ENOG4105D5G	Transposase
AC612_14055	ENOG4107BJW	polysaccharide deacetylase
AC612_14060	ENOG4105CND	Glycosyl transferase, family 2
AC612_14075	ENOG4105C26	Dehydrogenase
AC612_14090	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
AC612_14095	ENOG4105D4A	Cell wall formation (By similarity)
AC612_14100	ENOG4108SXK	Transporter Drug Metabolite Exporter family
AC612_14120	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
AC612_14130	ENOG4108UYB	regulatoR
AC612_14140	ENOG4105KU2	hydrolase family 5
AC612_14180	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
AC612_14185	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
AC612_14190	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
AC612_14195	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AC612_14200	ENOG4105DJ0	Poly(A) Polymerase
AC612_14210	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
AC612_14215	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
AC612_14225	ENOG4105F2I	Transposase
AC612_14260	ENOG4105D5G	Transposase
AC612_14270	ENOG4105CMG	Carbohydrate kinase
AC612_14320	ENOG4108RTU	Aldolase
AC612_14325	ENOG4105CXK	mandelate racemase muconate lactonizing
AC612_14335	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
AC612_14340	ENOG4108Z4U	Ferredoxin
AC612_14350	ENOG4107TUS	Dihydrodipicolinate synthase
AC612_14365	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AC612_14370	ENOG4108IAB	Phoh family
AC612_14410	ENOG4105CWB	LysR family transcriptional Regulator
AC612_14425	ENOG4107SDU	Methyl-accepting chemotaxis
AC612_14435	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
AC612_14440	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
AC612_14445	ENOG4105Y3E	Modulates RecA activity (By similarity)
AC612_14450	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
AC612_14455	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
AC612_14460	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
AC612_14465	ENOG4107TH8	cina domain protein
AC612_14470	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
AC612_14475	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
AC612_14480	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
AC612_14485	ENOG4105EEI	dihydropteroate synthase
AC612_14490	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AC612_14495	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
AC612_14500	ENOG4105HBR	Rna-binding protein
AC612_14510	ENOG4108K5P	(LipO)protein
AC612_14515	ENOG4108UM1	dedA family
AC612_14520	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
AC612_14525	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
AC612_14530	ENOG4108DG9	Smr protein MutS2
AC612_14535	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
AC612_14540	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
AC612_14545	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
AC612_14550	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
AC612_14555	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
AC612_14565	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
AC612_14570	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
AC612_14580	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AC612_14595	ENOG4105CJ3	phosphate transporter
AC612_14640	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AC612_14665	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AC612_14695	ENOG4105EGZ	biosynthesis protein
AC612_14745	ENOG4105EMN	RNA polymerase sigma factor
AC612_14760	ENOG41060IM	Heme exporter protein
AC612_14770	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
AC612_14775	ENOG4105DA4	cytochrome c-type biogenesis protein
AC612_14780	ENOG4107QX9	Thiol disulfide interChange protein
AC612_14785	ENOG4105KWW	Biogenesis protein
AC612_14795	ENOG4105CQZ	Histidine kinase
AC612_14805	ENOG4105BZU	Histidine kinase
AC612_14835	ENOG4105C8Q	Methyl-accepting chemotaxis
AC612_14850	ENOG4105D5G	Transposase
AC612_14870	ENOG4105CC0	LysR family Transcriptional regulator
AC612_14875	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
AC612_14880	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
AC612_14895	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
AC612_14905	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
AC612_14910	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
AC612_14915	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
AC612_14955	ENOG4105CI2	imidazolone-5-propionate hydrolase
AC612_14960	ENOG4105C84	Histidine ammonia-lyase
AC612_14970	ENOG4105CGP	Urocanate hydratase
AC612_14980	ENOG4105DZG	Dehydrogenase
AC612_14985	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AC612_14990	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
AC612_15000	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
AC612_15005	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
AC612_15010	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AC612_15020	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
AC612_15035	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
AC612_15040	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
AC612_15045	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
AC612_15050	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
AC612_15055	ENOG4105C5S	asparaginyl-tRNA synthetase
AC612_15090	ENOG4105F2I	Transposase
AC612_15095	ENOG4105WH1	Two component transcriptional regulator luxr family
AC612_15140	ENOG41077A9	carbonic anhydrase
AC612_15145	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
AC612_15155	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
AC612_15160	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
AC612_15165	ENOG4105CJB	Exodeoxyribonuclease I
AC612_15185	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
AC612_15190	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
AC612_15195	ENOG4105C5H	ABC transporter
AC612_15225	ENOG4105KHC	sulfurtransferase
AC612_15230	ENOG4105P8F	nudix hydrolase
AC612_15235	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AC612_15240	ENOG4105E39	Enoyl-CoA hydratase
AC612_15250	ENOG4105CSM	endonuclease III
AC612_15255	ENOG4105CHH	sulfate transporter
AC612_15260	ENOG4107B2H	carbonic anhydrase
AC612_15280	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
AC612_15285	ENOG4105C8U	phosphate abc transporter
AC612_15290	ENOG4105E2Z	phosphate ABC transporter (Permease
AC612_15295	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AC612_15300	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
AC612_15310	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
AC612_15320	ENOG4105C2N	RNA methyltransferase TrmH family group 3
AC612_15330	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
AC612_15345	ENOG4105C1G	acyl-Coa dehydrogenase
AC612_15350	ENOG4105C1G	acyl-Coa dehydrogenase
AC612_15360	ENOG4105C3R	Methionine synthase
AC612_15365	ENOG4105C3R	Methionine synthase
AC612_15375	ENOG4105D7K	pfkb domain protein
AC612_15385	ENOG4105ETE	Transcriptional regulator (LacI family
AC612_15400	ENOG41069P5	Protein slyX homolog
AC612_15405	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
AC612_15410	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AC612_15420	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
AC612_15425	ENOG4105CZV	ABC transporter
AC612_15455	ENOG4105C37	(CBS) domain
AC612_15465	ENOG4107QTF	adenylosuccinate lyase
AC612_15480	ENOG4105EZE	Cupin 4 family protein
AC612_15490	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
AC612_15495	ENOG4105C7S	Dehydrogenase
AC612_15505	ENOG4108URH	decarboxylase
AC612_15515	ENOG4105BZ1	(ABC) transporter
AC612_15520	ENOG4105C5Q	Transcriptional regulator
AC612_15560	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AC612_15565	ENOG4105CFG	Acts as a chaperone (By similarity)
AC612_15570	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AC612_15575	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
AC612_15580	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
AC612_15585	ENOG41090R7	Ferric uptake
AC612_15590	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
AC612_15600	ENOG4108Z1B	Cyclase dehydrase
AC612_15605	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
AC612_15620	ENOG4105D5G	Transposase
AC612_15650	ENOG4105D5G	Transposase
AC612_15665	ENOG4106TD9	Diguanylate cyclase
AC612_15675	ENOG4105BZU	Histidine kinase
AC612_15710	ENOG4105CR8	Transcriptional regulator
AC612_15715	ENOG4105CDV	Ompa motb domain protein
AC612_15720	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
AC612_15725	ENOG4105CDU	Replicative dna helicase
AC612_15735	ENOG4105CAQ	asparagine synthetase
AC612_15740	ENOG4108K3A	Glutathione S-transferase
AC612_15750	ENOG4105C1G	acyl-Coa dehydrogenase
AC612_15765	ENOG4105F8V	Hydrolase, tatD family
AC612_15770	ENOG4105CUZ	uba thif-type nad fad binding protein
AC612_15785	ENOG4105VEQ	Cold shock protein
AC612_15795	ENOG4105HDD	phospholipase
AC612_15810	ENOG4107GFK	fumarate
AC612_15820	ENOG4105DP0	ferredoxin-NADP reductase
AC612_15825	ENOG4108V06	Glutathione peroxidase
AC612_15830	ENOG4105DGW	oligopeptidase A
AC612_15860	ENOG4105DUX	Transporter
AC612_15885	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AC612_15890	ENOG4105CW7	secretion protein, HlyD family
AC612_15910	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AC612_15915	ENOG4105FQ6	thiopurine methyltransferase
AC612_15920	ENOG4108UWD	Iron-storage protein
AC612_15930	ENOG4108ESX	Receptor
AC612_15940	ENOG4105CAQ	asparagine synthetase
AC612_15945	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AC612_15950	ENOG4105KUZ	arsenate reductase
AC612_15960	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
AC612_15965	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
AC612_16000	ENOG4105CE9	30S ribosomal protein S2
AC612_16005	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
AC612_16010	ENOG4105BZU	Histidine kinase
AC612_16015	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
AC612_16020	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
AC612_16025	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AC612_16030	ENOG4105KNE	Phosphatidate cytidylyltransferase
AC612_16035	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
AC612_16040	ENOG4105DZP	Membrane-associated zinc metalloprotease
AC612_16055	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AC612_16060	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
AC612_16065	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AC612_16070	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AC612_16085	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
AC612_16100	ENOG4108YXA	Membrane
AC612_16155	ENOG4107QK5	Homocysteine s-methyltransferase
AC612_16160	ENOG4108IQI	permease
AC612_16165	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
AC612_16170	ENOG4105DA5	(ABC) transporter
AC612_16180	ENOG4105F2I	Transposase
AC612_16195	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
AC612_16225	ENOG4105K6V	RNA polymerase
AC612_16250	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
AC612_16265	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
AC612_16270	ENOG4105M4H	endoribonuclease L-psp
AC612_16315	ENOG4105F27	Major Facilitator
AC612_16320	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AC612_16325	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
AC612_16335	ENOG4108YZY	peptidylprolyl cis-trans isomerase
AC612_16355	ENOG4105D5G	Transposase
AC612_16360	ENOG4105KSC	Transcriptional regulator, TraR DksA family
AC612_16375	ENOG4108VKG	metal-dependent hydrolase
AC612_16390	ENOG4105CHU	acetyl-coa acetyltransferase
AC612_16405	ENOG4105BZU	Histidine kinase
AC612_16420	ENOG4107T0X	DNA ligase
AC612_16430	ENOG4107T0X	DNA ligase
AC612_16435	ENOG4107QRT	dEAD DEAH box helicase
AC612_16445	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
AC612_16450	ENOG4105VEQ	Cold shock protein
AC612_16455	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
AC612_16460	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
AC612_16465	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
AC612_16470	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
AC612_16475	ENOG4108QDE	fad dependent oxidoreductase
AC612_16480	ENOG4107ZXU	DSBA oxidoreductase
AC612_16485	ENOG41080ZE	Adenylate cyclase
AC612_16490	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AC612_16500	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
AC612_16505	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
AC612_16510	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
AC612_16520	ENOG4105C3F	Signal peptidase i
AC612_16525	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
AC612_16530	ENOG4105C0H	protease
AC612_16540	ENOG4105EMN	RNA polymerase sigma factor
AC612_16545	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AC612_16555	ENOG4105F2I	Transposase
AC612_16565	ENOG4105BZU	Histidine kinase
AC612_16570	ENOG4105ETX	regulatoR
AC612_16580	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AC612_16590	ENOG4105F2I	Transposase
AC612_16615	ENOG4105D5G	Transposase
AC612_16630	ENOG4105F2I	Transposase
AC612_16640	ENOG4105F2I	Transposase
AC612_16655	ENOG4105F2I	Transposase
AC612_16670	ENOG4108YGG	dna repair protein
AC612_16675	ENOG4105D5G	Transposase
AC612_16685	ENOG4105D5G	Transposase
AC612_16735	ENOG4105D5G	Transposase
AC612_16740	ENOG4105D5G	Transposase
AC612_16770	ENOG4105D5G	Transposase
AC612_16780	ENOG4105D5G	Transposase
AC612_16790	ENOG4105D5G	Transposase
AC612_16835	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
AC612_16840	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
AC612_16870	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
AC612_16885	ENOG4105ETE	Transcriptional regulator (LacI family
AC612_16910	ENOG4105EIB	trna rrna methyltransferase
AC612_16920	ENOG4105CD8	aminopeptidase N
AC612_16925	ENOG4105BZS	acriflavin resistance protein
AC612_16935	ENOG4105F2I	Transposase
AC612_16940	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
AC612_16945	ENOG4105C11	sulfate adenylyltransferase), subunit 2
AC612_16950	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
AC612_16955	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
AC612_16960	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
AC612_16965	ENOG4105F2I	Transposase
AC612_16985	ENOG4105BZU	Histidine kinase
AC612_16995	ENOG4107R11	Transcriptional regulator
AC612_17015	ENOG4108UVJ	appr-1-p processing domain protein
AC612_17020	ENOG4107R1Y	fructose-bisphosphate aldolase
AC612_17025	ENOG4105CA9	Pyruvate kinase
AC612_17035	ENOG4105BZA	Phosphoglycerate kinase
AC612_17055	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AC612_17065	ENOG4105EIF	outer membrane protein W
AC612_17070	ENOG4105EIF	outer membrane protein W
AC612_17080	ENOG4107S76	domain protein
AC612_17085	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
AC612_17090	ENOG4105E0C	molybdate abc transporter
AC612_17095	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
AC612_17130	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
AC612_17135	ENOG4105DR5	peptidase
AC612_17140	ENOG4105CNM	Receptor
AC612_17160	ENOG4105CV1	Transketolase (EC 2.2.1.1)
AC612_17165	ENOG4105CK2	sodium dicarboxylate symporter
AC612_17175	ENOG4107QVM	von Willebrand factor, type A
AC612_17195	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AC612_17200	ENOG4105E4G	Type IV pilus
AC612_17225	ENOG4108JQC	penicillin-binding protein 1A
AC612_17240	ENOG4105NRA	50s ribosomal protein l31 type b
AC612_17245	ENOG4105DU0	nucleoside hydrolase
AC612_17250	ENOG4105CB5	ATP-dependent DNA helicase recG
AC612_17255	ENOG4105KME	endoribonuclease L-psp
AC612_17260	ENOG4105CTX	dehydratase
AC612_17265	ENOG4105EPF	Outer membrane porin
AC612_17275	ENOG4105DJB	Major Facilitator Superfamily
AC612_17290	ENOG4106NZI	LysR family Transcriptional regulator
AC612_17295	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AC612_17300	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
AC612_17305	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
AC612_17310	ENOG4105DSJ	YicC domain protein
AC612_17315	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
AC612_17325	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AC612_17330	ENOG4105CSA	Coproporphyrinogen iii oxidase
AC612_17345	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
AC612_17355	ENOG4107RAQ	aminopeptidase
AC612_17370	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
AC612_17375	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
AC612_17385	ENOG4105E66	phosphoriboisomerase A
AC612_17395	ENOG41063JG	Transcriptional regulator
AC612_17400	ENOG4105VCQ	rubredoxin
AC612_17405	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
AC612_17420	ENOG41061ZR	Transcriptional regulator
AC612_17430	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AC612_17460	ENOG4105C8Y	Acetylornithine aminotransferase
AC612_17465	ENOG4105EYW	Ion transport protein
AC612_17470	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
AC612_17480	ENOG410841Q	phosphoesterase PA-phosphatase related protein
AC612_17485	ENOG4105FFC	UPF0187 protein
AC612_17495	ENOG4105DFU	Cell wall formation (By similarity)
AC612_17500	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
AC612_17515	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AC612_17525	ENOG4105F0N	pyrophosphate phospho-hydrolase
AC612_17540	ENOG4105D5G	Transposase
AC612_17555	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
AC612_17565	ENOG4105C8Q	Methyl-accepting chemotaxis
AC612_17570	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
AC612_17575	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
AC612_17590	ENOG4105C7B	Threonine dehydratase
AC612_17595	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AC612_17600	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AC612_17605	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AC612_17610	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AC612_17615	ENOG4108MP6	LysR family Transcriptional regulator
AC612_17630	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
AC612_17635	ENOG4105DFG	type I secretion outer membrane protein
AC612_17640	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
AC612_17645	ENOG4105D1S	lipid A biosynthesis
AC612_17670	ENOG4105C6K	Malic enzyme
AC612_17675	ENOG4105CK2	sodium dicarboxylate symporter
AC612_17685	ENOG4105CQZ	Histidine kinase
AC612_17690	ENOG4105CSH	Transporter
AC612_17700	ENOG4105F04	LysR family Transcriptional regulator
AC612_17710	ENOG4105CPC	Aldo Keto reductase
AC612_17725	ENOG4105WH1	Two component transcriptional regulator luxr family
AC612_17730	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
AC612_17735	ENOG4105DHQ	Histidine kinase
AC612_17750	ENOG4105D4T	Citrate transporter
AC612_17755	ENOG4105CHR	reductase
AC612_17760	ENOG4105ETE	Transcriptional regulator (LacI family
AC612_17775	ENOG4107QW3	Sucrose phosphorylase
AC612_17790	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
AC612_17795	ENOG4105CHM	Aminotransferase
AC612_17830	ENOG41069H0	dihydroorotase EC 3.5.2.3
AC612_17835	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AC612_17855	ENOG4105F2I	Transposase
AC612_17860	ENOG4108RMV	DegV Family
AC612_17865	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AC612_17885	ENOG4105EJG	cellulose synthase
AC612_17890	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
AC612_17895	ENOG4107EEX	Cellulose synthase regulator protein
AC612_17900	ENOG4107QZ7	Cellulose synthase catalytic subunit
AC612_17915	ENOG4107RH7	Nicotinate phosphoribosyltransferase
AC612_17965	ENOG4106S9K	Transcriptional regulator
AC612_17980	ENOG4105GVR	general secretion pathway protein D
AC612_17990	ENOG410678M	general secretion pathway protein M
AC612_17995	ENOG41090VX	general secretion pathway protein L
AC612_18000	ENOG4105UV2	general secretion pathway protein K
AC612_18005	ENOG41069G9	General secretion pathway protein J
AC612_18015	ENOG4105WMT	general secretion pathway protein h
AC612_18025	ENOG4105D7Q	type ii secretion system
AC612_18030	ENOG4107QHF	type ii secretion system protein e
AC612_18035	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AC612_18045	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AC612_18050	ENOG4105EUR	Domain-Containing protein
AC612_18060	ENOG4108ETH	Formylglycinamide ribotide synthetase
AC612_18065	ENOG4105T95	Thiol disulfide interChange protein
AC612_18070	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AC612_18085	ENOG4108K5H	permease YjgP YjgQ family protein
AC612_18095	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AC612_18110	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
AC612_18130	ENOG4105D5G	Transposase
AC612_18155	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
AC612_18165	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
AC612_18170	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
AC612_18185	ENOG4105DHJ	ABC, transporter
AC612_18190	ENOG4108SNX	Mammalian cell entry related domain protein
AC612_18205	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
AC612_18220	ENOG4107QKV	phosphomannomutase
AC612_18225	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
AC612_18235	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
AC612_18240	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
AC612_18255	ENOG4105BZJ	Electron transfer flavoprotein
AC612_18260	ENOG4105C10	Electron transfer flavoprotein
AC612_18295	ENOG4108DMA	Nad-dependent epimerase dehydratase
AC612_18300	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
AC612_18305	ENOG4105CGN	Glycosyl transferase (Group 1
AC612_18315	ENOG4105EY8	ABC transporter
AC612_18325	ENOG4107STW	synthase
AC612_18330	ENOG4105C28	cystathionine
AC612_18355	ENOG4105CZX	twitching motility protein
AC612_18360	ENOG4108RXX	maleylacetoacetate isomerase
AC612_18370	ENOG4105C1J	atp-dependent rna helicase
AC612_18380	ENOG4105D05	Receptor
AC612_18385	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
AC612_18415	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
AC612_18435	ENOG4105NIV	Esterase
AC612_18440	ENOG4107RNH	Outer membrane receptor FepA
AC612_18445	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AC612_18450	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AC612_18455	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
AC612_18470	ENOG4105DGW	oligopeptidase A
AC612_18520	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AC612_18525	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
AC612_18530	ENOG4105C19	ABC transporter
AC612_18535	ENOG4107RBB	ABC transporter, permease
AC612_18540	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AC612_18550	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AC612_18555	ENOG4105BZU	Histidine kinase
AC612_18560	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AC612_18580	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
AC612_18585	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
AC612_18590	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
AC612_18595	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
AC612_18600	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AC612_18605	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AC612_18610	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AC612_18615	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
AC612_18635	ENOG4107QN2	dihydrolipoyl dehydrogenase
AC612_18645	ENOG4107QSN	dihydrolipoamide acetyltransferase
AC612_18680	ENOG4105D01	(LipO)protein
AC612_18685	ENOG4108UMI	ABC transporter, permease
AC612_18690	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
AC612_18695	ENOG4108EHX	EamA-like transporter family
AC612_18700	ENOG4108VPT	UPF0234 protein
AC612_18710	ENOG4105BZU	Histidine kinase
AC612_18730	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
AC612_18745	ENOG4105I08	Pseudouridine synthase
AC612_18750	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
AC612_18770	ENOG4105BZU	Histidine kinase
AC612_18790	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AC612_18795	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
AC612_18800	ENOG4105EW9	transcriptional regulator AsnC family
AC612_18820	ENOG4107RD7	Flagellar Motor Protein, MotA
AC612_18825	ENOG4105ER2	Ompa motb domain protein
AC612_18855	ENOG4105DA5	(ABC) transporter
AC612_18860	ENOG4105EEQ	Na H antiporter
AC612_18870	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
AC612_18880	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
AC612_18890	ENOG4105CBN	LysR family transcriptional regulator
AC612_18900	ENOG4105CPC	Aldo Keto reductase
AC612_18910	ENOG4105C9K	Endothelin-converting enzyme 1
AC612_18925	ENOG4107QTZ	amino acid
AC612_18935	ENOG4108VAC	response regulator
AC612_18940	ENOG4105C2F	Histidine kinase
AC612_18955	ENOG4108Z9Z	response to DNA damage stimulus
AC612_18960	ENOG4105WEF	catalase
AC612_18980	ENOG4105BZU	Histidine kinase
AC612_18995	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AC612_19005	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AC612_19010	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AC612_19025	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
AC612_19030	ENOG4105CMR	udp-glucose 4-epimerase
AC612_19050	ENOG4105BZ1	(ABC) transporter
AC612_19065	ENOG4105E2A	Dehydrogenase
AC612_19125	ENOG4105CIG	ABC transporter
AC612_19140	ENOG4108UQ8	endoribonuclease L-psp
AC612_19170	ENOG4105HEI	LysR family (Transcriptional regulator
AC612_19175	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
AC612_19205	ENOG4105CHH	sulfate transporter
AC612_19240	ENOG4105F2I	Transposase
AC612_19255	ENOG4105F2I	Transposase
AC612_19265	ENOG4105D5G	Transposase
AC612_19280	ENOG4105D5G	Transposase
AC612_19300	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AC612_19305	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
AC612_19310	ENOG4105D1S	lipid A biosynthesis
AC612_19315	ENOG4108Z7F	N-acetyltransferase
AC612_19360	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AC612_19365	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
AC612_19370	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AC612_19375	ENOG4108WZM	domain protein
AC612_19380	ENOG4105C79	DNA protecting protein DprA
AC612_19385	ENOG4108RPN	Protein smg homolog
AC612_19400	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AC612_19405	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AC612_19420	ENOG4107ZQV	short-chain dehydrogenase reductase
AC612_19435	ENOG4105D07	Signal peptide peptidase, SppA
AC612_19440	ENOG4107QI1	Mate efflux family protein
AC612_19460	ENOG4105C25	Primosomal protein n'
AC612_19465	ENOG4108TGY	Glutathione S-transferase
AC612_19490	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AC612_19495	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
AC612_19500	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AC612_19505	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
AC612_19510	ENOG4105CAK	Cell division ATP-binding protein ftsE
AC612_19515	ENOG4105C1J	atp-dependent rna helicase
AC612_19520	ENOG4105K63	Thioredoxin
AC612_19525	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
AC612_19530	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
AC612_19535	ENOG4105ETT	transcriptional Regulator, LysR family
AC612_19545	ENOG4105E9K	Isocitrate dehydrogenase
AC612_19555	ENOG4109066	lysm domain bon superfamily protein
AC612_19560	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
AC612_19565	ENOG4105CH2	amidohydrolase
AC612_19570	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
AC612_19575	ENOG4105BZS	acriflavin resistance protein
AC612_19595	ENOG4105E32	cytoplasmic protein
AC612_19635	ENOG4108UQS	dipeptidase
AC612_19640	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
AC612_19650	ENOG4105DTQ	mandelate racemase muconate lactonizing
AC612_19660	ENOG4105D5Q	Arginine ornithine antiporter
AC612_19680	ENOG4108Z12	YiaAB two helix domain-containing protein
AC612_19705	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
AC612_19710	ENOG4107ZVW	dihydroneopterin aldolase
AC612_19715	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AC612_19720	ENOG4105VCC	30S ribosomal protein S21
AC612_19725	ENOG4105KTH	gatB Yqey
AC612_19730	ENOG4107S2Z	UPF0761 membrane protein
AC612_19735	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
AC612_19740	ENOG4105DHU	Bile acid
AC612_19750	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
AC612_19775	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
AC612_19780	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
AC612_19795	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
AC612_19805	ENOG4105C26	Dehydrogenase
AC612_19840	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
AC612_19845	ENOG4105DR5	peptidase
AC612_19850	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
AC612_19860	ENOG4105EYM	Major Facilitator superfamily
AC612_19865	ENOG4105CGK	Exodeoxyribonuclease III
AC612_19870	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AC612_19880	ENOG4107QJE	Chromosome Partitioning Protein
AC612_19885	ENOG4105FA0	parb-like partition protein
AC612_19905	ENOG4105CKK	Glycosyl transferase, family 2
AC612_19925	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
AC612_19930	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
AC612_19935	ENOG4105W5Q	DNA repair protein (RadC
AC612_19940	ENOG4105C75	arginyL-tRNA synthetase
AC612_19955	ENOG4105EMU	Dehydrogenase
AC612_19960	ENOG4105EXC	Acyl-transferase
AC612_19975	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
AC612_19980	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
AC612_20005	ENOG4105CPE	K01197 hyaluronoglucosaminidase EC 3.2.1.35
AC612_20010	ENOG4108YZA	Nitrogen regulatory protein pii
AC612_20015	ENOG4105W0Z	cytoplasmic protein
AC612_20020	ENOG4105C0P	Mg chelatase subunit ChlI
AC612_20035	ENOG41066DG	(EAL) domain protein
AC612_20050	ENOG4105EJ2	Transcriptional regulator
AC612_20065	ENOG4105F2I	Transposase
AC612_20075	ENOG4105E0Y	RtcB Protein
AC612_20115	ENOG4105ECP	epimerase
AC612_20120	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
AC612_20125	ENOG4105DHQ	Histidine kinase
AC612_20145	ENOG4105C0H	protease
AC612_20165	ENOG4105DSF	transport protein
AC612_20170	ENOG4107URF	beta-phospho-glucomutase
AC612_20175	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AC612_20195	ENOG4107VGR	Catalase
AC612_20210	ENOG4108S01	response regulator
AC612_20215	ENOG4108ZGX	Histidine kinase
AC612_20220	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
AC612_20225	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AC612_20250	ENOG4105FDR	Membrane
AC612_20270	ENOG4108NNI	Beta-lactamase domain-containing protein
AC612_20275	ENOG4105C31	Tryptophanyl-tRNA synthetase
AC612_20280	ENOG4105D5G	Transposase
AC612_20285	ENOG4105VDW	Csbd family
AC612_20345	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
AC612_20370	ENOG4105E0F	Histidine kinase
AC612_20375	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
AC612_20385	ENOG4105F2I	Transposase
AC612_20390	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AC612_20405	ENOG4105CH6	catalase
AC612_20410	ENOG4105DVT	helicase
AC612_20425	ENOG4105E2X	shikimate dehydrogenase
AC612_20435	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
AC612_20455	ENOG4105D52	delta-aminolevulinic acid dehydratase
AC612_20485	ENOG4105CYM	Glutathione S-transferase
AC612_20510	ENOG4105QV4	Tryptophan halogenase
AC612_20525	ENOG4108IUW	ABC transporter
AC612_20535	ENOG4105VZ8	Transcriptional regulator
AC612_20555	ENOG4105PGM	cation diffusion facilitator family transporter
AC612_20565	ENOG4105E0K	tonB-dependent siderophore receptor
AC612_20575	ENOG4105ECQ	AraC Family Transcriptional Regulator
AC612_20580	ENOG4107SC0	ferredoxin--NADP reductase
AC612_20585	ENOG4105DA5	(ABC) transporter
AC612_20590	ENOG4105E3A	(ABC) transporter
AC612_20595	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
AC612_20625	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AC612_20630	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AC612_20640	ENOG4105CD5	CoA-binding domain protein
AC612_20645	ENOG4105CJW	magnesium transporter
AC612_20660	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
AC612_20665	ENOG4105BZP	glycoside hydrolase 15-related
AC612_20685	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AC612_20695	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
AC612_20740	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
AC612_20745	ENOG4105E9Q	Acyl-transferase
AC612_20755	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AC612_20780	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
AC612_20785	ENOG4105F2I	Transposase
AC612_20800	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
AC612_20805	ENOG4105C2M	dna polymerase I
AC612_20835	ENOG4107TPY	serine threonine protein kinase
AC612_20875	ENOG4105CS6	Rhs element vgr protein
AC612_20900	ENOG4108SF5	RNA Polymerase
AC612_20915	ENOG4105D6F	Phosphatase
AC612_20945	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AC612_20970	ENOG4108WC9	type VI secretion system effector, hcp1 family
AC612_21005	ENOG4105C4R	Atp-dependent dna helicase
AC612_21015	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
AC612_21020	ENOG4106NZI	LysR family Transcriptional regulator
AC612_21025	ENOG4105JSC	dimethylmenaquinone methyltransferase
AC612_21040	ENOG4105W0E	50S ribosomal protein L33
AC612_21045	ENOG4105KDC	50s ribosomal protein l28
AC612_21055	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
AC612_21075	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
AC612_21080	ENOG4105DGI	Alkaline phosphatase
AC612_21110	ENOG4105CGK	Exodeoxyribonuclease III
AC612_21115	ENOG4105E2R	ROK family
AC612_21125	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
AC612_21135	ENOG4107QN1	sodium solute
AC612_21140	ENOG41062QD	Membrane
AC612_21150	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AC612_21200	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
AC612_21205	ENOG4105ERH	Fumarylacetoacetate hydrolase
AC612_21210	ENOG4105DIA	mandelate racemase muconate lactonizing
AC612_21215	ENOG4105QJH	Domain of unknown function (DUF718)
AC612_21220	ENOG4105EDR	glucose galactose transporter
AC612_21225	ENOG4108K2P	TRANSCRIPTIONal
AC612_21230	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
AC612_21235	ENOG4105BZU	Histidine kinase
AC612_21245	ENOG4105E2V	Glycosyltransferase 36
AC612_21250	ENOG4105CT4	transporter
AC612_21255	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
AC612_21280	ENOG4105MA0	exported protein
AC612_21285	ENOG4105CFU	surface antigen
AC612_21295	ENOG4105F2I	Transposase
AC612_21300	ENOG4105F2I	Transposase
AC612_21305	ENOG4105F2I	Transposase
AC612_21335	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
AC612_21340	ENOG4107QHF	type ii secretion system protein e
AC612_21350	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AC612_21360	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
AC612_21365	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
AC612_21380	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
AC612_21400	ENOG4105DH7	May be involved in recombination (By similarity)
AC612_21405	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
AC612_21410	ENOG4105C93	Xylose Isomerase
AC612_21415	ENOG4105ETE	Transcriptional regulator (LacI family
AC612_21420	ENOG4105D0H	Alpha-glucuronidase (EC 3.2.1.139)
AC612_21430	ENOG4105CXK	mandelate racemase muconate lactonizing
AC612_21445	ENOG4105DEI	Mannitol dehydrogenase
AC612_21515	ENOG4105F2I	Transposase
AC612_21525	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
AC612_21530	ENOG4105CNT	hydrolase family 2
AC612_21535	ENOG4105D2H	Uronic isomerase
AC612_21570	ENOG4105CT4	transporter
AC612_21575	ENOG4105DT9	hydrolase family 43
AC612_21610	ENOG4105E55	glycerol-3-phosphate acyltransferase
AC612_21620	ENOG4105ETE	Transcriptional regulator (LacI family
AC612_21640	ENOG4105QV4	Tryptophan halogenase
AC612_21645	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
AC612_21650	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
AC612_21655	ENOG4108YXG	UPF0502 protein
AC612_21665	ENOG4105KNA	-acetyltransferase
AC612_21670	ENOG4105C4R	Atp-dependent dna helicase
AC612_21675	ENOG4107104	thymidine kinase
AC612_21680	ENOG4105BZU	Histidine kinase
AC612_21685	ENOG4105DJ9	glucan biosynthesis protein
AC612_21695	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
AC612_21725	ENOG4105DKK	Benzoate
AC612_21745	ENOG4105DSB	aldose 1-epimerase
AC612_21755	ENOG4105K5B	UPF0225 protein
AC612_21760	ENOG4105EJ9	Membrane
AC612_21770	ENOG4105D5G	Transposase
AC612_21790	ENOG4105EUJ	GTP cyclohydrolase i
AC612_21800	ENOG4105ZQC	membrane protein AaeX
AC612_21805	ENOG4105Y49	secretion protein, HlyD family
AC612_21815	ENOG4105DR8	Membrane
AC612_21820	ENOG4105CSH	Transporter
AC612_21830	ENOG410642W	LysR family Transcriptional regulator
AC612_21835	ENOG4105EMU	Dehydrogenase
AC612_21845	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
AC612_21865	ENOG4105D5G	Transposase
AC612_21890	ENOG4105D3G	Pseudouridine synthase
AC612_21915	ENOG4105F2I	Transposase
AC612_21930	ENOG4105D5G	Transposase
AC612_21950	ENOG4107QYX	exodeoxyribonuclease v alpha
AC612_21955	ENOG4107QKA	exodeoxyribonuclease V beta
AC612_21960	ENOG4105DSY	exodeoxyribonuclease V, gamma
AC612_21995	ENOG4105DHJ	ABC, transporter
AC612_22000	ENOG4105CY3	ABC transporter, permease
AC612_22005	ENOG4107PE3	Mammalian cell entry related domain protein
AC612_22020	ENOG410903C	(LipO)protein
AC612_22030	ENOG4108V06	Glutathione peroxidase
AC612_22055	ENOG4108TGY	Glutathione S-transferase
AC612_22110	ENOG4105VXN	addiction module toxin, RelE StbE family
AC612_22165	ENOG4105C8Q	Methyl-accepting chemotaxis
AC612_22190	ENOG4108C33	Resolvase
AC612_22225	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
AC612_22250	ENOG4105CWX	Alpha-1,2-mannosidase
AC612_22255	ENOG4105NRM	Membrane
AC612_22270	ENOG4105BZW	Glycerate kinase
AC612_22275	ENOG4105CSP	Major Facilitator Superfamily
AC612_22290	ENOG4105DR4	Methyltransferase
AC612_22295	ENOG4105DU1	integral membrane protein, terc
AC612_22305	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
AC612_22320	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
AC612_22330	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AC612_22335	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
AC612_22355	ENOG4106H6R	UPF0380 protein
AC612_22395	ENOG4105D5G	Transposase
AC612_22400	ENOG4105D5G	Transposase
AC612_22440	ENOG4105D5G	Transposase
AC612_22495	ENOG4105CVE	Lytic murein transglycosylase
AC612_22510	ENOG4105D5G	Transposase