locus-tag	class	description
DGN11_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DGN11_00025	COG0187	DNA topoisomerase II activity
DGN11_00035	COG0501	Belongs to the peptidase M48B family
DGN11_00075	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DGN11_00085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DGN11_00135	COG0793	Belongs to the peptidase S41A family
DGN11_00140	COG4942	peptidase
DGN11_00150	COG2234	aminopeptidase activity
DGN11_00160	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DGN11_00165	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DGN11_00175	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DGN11_00185	COG1064	alcohol dehydrogenase
DGN11_00190	COG0493	'glutamate synthase
DGN11_00195	COG0067	glutamate synthase
DGN11_00195	COG0069	glutamate synthase activity
DGN11_00195	COG0070	glutamate synthase
DGN11_00235	COG3328	transposase activity
DGN11_00285	COG1205	dead DEAH box helicase
DGN11_00285	COG1111	helicase
DGN11_00290	COG1272	protein, Hemolysin III
DGN11_00310	COG1028	Short-chain dehydrogenase reductase Sdr
DGN11_00315	COG1028	Short-chain dehydrogenase reductase Sdr
DGN11_00345	COG2249	NAD(P)H dehydrogenase (quinone) activity
DGN11_00365	COG3039	Transposase
DGN11_00395	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DGN11_00410	COG1125	glycine betaine transport
DGN11_00410	COG0517	IMP dehydrogenase activity
DGN11_00425	COG1119	ATPase activity
DGN11_00435	COG1752	Esterase of the alpha-beta hydrolase superfamily
DGN11_00445	COG1522	sequence-specific DNA binding
DGN11_00450	COG3186	Phenylalanine-4-hydroxylase
DGN11_00460	COG2755	lipolytic protein G-D-S-L family
DGN11_00470	COG1028	Short-chain dehydrogenase reductase Sdr
DGN11_00475	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
DGN11_00490	COG1609	Transcriptional regulator
DGN11_00495	COG3507	Belongs to the glycosyl hydrolase 43 family
DGN11_00510	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DGN11_00520	COG2755	lipolytic protein G-D-S-L family
DGN11_00520	COG0657	acetylesterase activity
DGN11_00540	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DGN11_00545	COG0366	Alpha amylase catalytic
DGN11_00550	COG0366	Alpha amylase catalytic
DGN11_00555	COG3039	Transposase
DGN11_00580	COG3039	Transposase
DGN11_00610	COG3328	transposase activity
DGN11_00635	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DGN11_00640	COG3710	Transcriptional regulator
DGN11_00660	COG2197	response regulator
DGN11_00665	COG4585	Histidine kinase
DGN11_00680	COG1304	FMN binding
DGN11_00705	COG1012	belongs to the aldehyde dehydrogenase family
DGN11_00720	COG4772	TonB-dependent receptor
DGN11_00730	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
DGN11_00765	COG0714	Associated with various cellular activities
DGN11_00810	COG0477	Major facilitator Superfamily
DGN11_00820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DGN11_00870	COG3237	CsbD-like
DGN11_00880	COG3039	Transposase
DGN11_00890	COG0489	protein tyrosine kinase activity
DGN11_00895	COG2062	phosphohistidine phosphatase, SixA
DGN11_00905	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DGN11_00950	COG1968	undecaprenyl-diphosphatase activity
DGN11_00960	COG0174	glutamine synthetase
DGN11_00965	COG0347	Belongs to the P(II) protein family
DGN11_00970	COG0004	ammonium transporteR
DGN11_00975	COG3852	Histidine kinase
DGN11_00980	COG2204	response regulator
DGN11_00985	COG2032	superoxide dismutase activity
DGN11_00990	COG2032	superoxide dismutase activity
DGN11_01000	COG3039	Transposase
DGN11_01015	COG0183	Belongs to the thiolase family
DGN11_01050	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DGN11_01055	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
DGN11_01060	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DGN11_01075	COG0028	Belongs to the TPP enzyme family
DGN11_01080	COG2205	protein histidine kinase activity
DGN11_01105	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DGN11_01120	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DGN11_01130	COG0596	Alpha beta hydrolase
DGN11_01135	COG0727	PFAM Uncharacterised protein family (UPF0153)
DGN11_01140	COG0318	PFAM AMP-dependent synthetase and ligase
DGN11_01145	COG0745	RESPONSE REGULATOR receiver
DGN11_01155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DGN11_01185	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DGN11_01195	COG0564	pseudouridine synthase activity
DGN11_01215	COG1446	asparaginase
DGN11_01220	COG0339	signal peptide processing
DGN11_01255	COG0475	glutathione-regulated potassium exporter activity
DGN11_01260	COG0583	DNA-binding transcription factor activity
DGN11_01265	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DGN11_01270	COG2224	Isocitrate lyase
DGN11_01300	COG4770	biotin carboxylase activity
DGN11_01305	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DGN11_01310	COG1960	acyl-CoA dehydrogenase activity
DGN11_01375	COG0697	spore germination
DGN11_01385	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DGN11_01390	COG1846	Transcriptional regulator
DGN11_01395	COG1764	response to oxidative stress
DGN11_01425	COG2130	NADP-dependent
DGN11_01440	COG1187	pseudouridine synthase activity
DGN11_01455	COG1643	Atp-dependent helicase
DGN11_01465	COG4807	Protein conserved in bacteria
DGN11_01470	COG2351	hydroxyisourate hydrolase activity
DGN11_01475	COG2072	flavoprotein involved in K transport
DGN11_01495	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DGN11_01505	COG0583	DNA-binding transcription factor activity
DGN11_01540	COG2252	PERMEase
DGN11_01565	COG0084	hydrolase, TatD family'
DGN11_01575	COG0583	DNA-binding transcription factor activity
DGN11_01580	COG2814	Major facilitator Superfamily
DGN11_01590	COG2267	carboxylic ester hydrolase activity
DGN11_01595	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DGN11_01600	COG1902	pentaerythritol trinitrate reductase activity
DGN11_01620	COG0745	RESPONSE REGULATOR receiver
DGN11_01625	COG2205	protein histidine kinase activity
DGN11_01630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DGN11_01650	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DGN11_01655	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DGN11_01660	COG0583	DNA-binding transcription factor activity
DGN11_01695	COG0702	epimerase
DGN11_01700	COG1733	regulation of RNA biosynthetic process
DGN11_01735	COG3328	transposase activity
DGN11_01750	COG3039	Transposase
DGN11_01760	COG0129	dihydroxy-acid dehydratase activity
DGN11_01775	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DGN11_01830	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DGN11_01835	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DGN11_01860	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DGN11_01865	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DGN11_01875	COG3485	protocatechuate 3,4-dioxygenase
DGN11_01880	COG3485	protocatechuate 3,4-dioxygenase
DGN11_01890	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DGN11_01895	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DGN11_01910	COG1414	Transcriptional regulator
DGN11_01920	COG0657	acetylesterase activity
DGN11_01930	COG0445	tRNA wobble uridine modification
DGN11_01940	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DGN11_01970	COG1028	Short-chain dehydrogenase reductase Sdr
DGN11_01975	COG2267	carboxylic ester hydrolase activity
DGN11_01985	COG0156	8-amino-7-oxononanoate synthase activity
DGN11_01990	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DGN11_01995	COG1040	competence protein
DGN11_02005	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DGN11_02035	COG3039	Transposase
DGN11_02100	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DGN11_02175	COG3264	Mechanosensitive ion channel
DGN11_02175	COG1511	domain protein
DGN11_02180	COG1368	sulfuric ester hydrolase activity
DGN11_02185	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DGN11_02190	COG2354	Protein conserved in bacteria
DGN11_02200	COG0297	glycogen (starch) synthase activity
DGN11_02205	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DGN11_02210	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DGN11_02235	COG0702	epimerase
DGN11_02240	COG1028	Short-chain dehydrogenase reductase Sdr
DGN11_02275	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DGN11_02280	COG1028	Short-chain dehydrogenase reductase Sdr
DGN11_02290	COG0513	Belongs to the DEAD box helicase family
DGN11_02295	COG0508	dehydrogenase complex catalyzes the overall conversion of
DGN11_02310	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DGN11_02320	COG3483	tryptophan 2,3-dioxygenase activity
DGN11_02325	COG3104	oligopeptide transport
DGN11_02365	COG1320	monovalent cation:proton antiporter activity
DGN11_02370	COG2212	antiporter activity
DGN11_02380	COG0651	ATP synthesis coupled electron transport
DGN11_02385	COG1006	Multisubunit Na H antiporter MnhC subunit
DGN11_02390	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DGN11_02390	COG2111	Na H antiporter
DGN11_02415	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DGN11_02420	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
DGN11_02435	COG0456	acetyltransferase
DGN11_02440	COG1597	lipid kinase activity
DGN11_02470	COG3039	Transposase
DGN11_02490	COG3039	Transposase
DGN11_02510	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DGN11_02515	COG0134	indole-3-glycerol-phosphate synthase activity
DGN11_02525	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DGN11_02530	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
DGN11_02540	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
DGN11_02550	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DGN11_02565	COG1051	belongs to the nudix hydrolase family
DGN11_02605	COG0316	Belongs to the HesB IscA family
DGN11_02620	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DGN11_02635	COG2814	Major facilitator Superfamily
DGN11_02645	COG2814	Major facilitator Superfamily
DGN11_02650	COG1289	transmembrane transporter activity
DGN11_02655	COG0151	Belongs to the GarS family
DGN11_02665	COG0138	bifunctional purine biosynthesis protein purh
DGN11_02670	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DGN11_02680	COG2453	phosphatase
DGN11_02680	COG0671	phosphoesterase, PA-phosphatase related
DGN11_02705	COG4589	Belongs to the CDS family
DGN11_02710	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
DGN11_02735	COG2264	protein methyltransferase activity
DGN11_02755	COG0439	Biotin carboxylase
DGN11_02765	COG0511	ligase activity, forming carbon-carbon bonds
DGN11_02770	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DGN11_02780	COG1324	tolerance protein
DGN11_02790	COG2356	endonuclease I
DGN11_02800	COG0459	protein refolding
DGN11_02815	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DGN11_02830	COG3386	PFAM SMP-30 Gluconolaconase
DGN11_02840	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DGN11_02845	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DGN11_02870	COG0778	Nitroreductase
DGN11_02875	COG2353	YceI-like domain
DGN11_02905	COG3052	prosthetic group binding
DGN11_02930	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DGN11_02940	COG1802	Transcriptional regulator
DGN11_02995	COG3328	transposase activity
DGN11_03020	COG3039	Transposase
DGN11_03060	COG3328	transposase activity
DGN11_03085	COG1082	Xylose isomerase domain protein TIM barrel
DGN11_03100	COG3328	transposase activity
DGN11_03110	COG3039	Transposase
DGN11_03125	COG4221	oxidoreductase activity
DGN11_03140	COG4221	oxidoreductase activity
DGN11_03150	COG0435	Glutathione S-transferase
DGN11_03185	COG1506	peptidase
DGN11_03185	COG0823	Involved in the tonB-independent uptake of proteins
DGN11_03230	COG0697	spore germination
DGN11_03250	COG1113	amino acid transport
DGN11_03270	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
DGN11_03320	COG0840	transmembrane signaling receptor activity
DGN11_03325	COG5297	Belongs to the glycosyl hydrolase family 6
DGN11_03325	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DGN11_03330	COG0659	secondary active sulfate transmembrane transporter activity
DGN11_03360	COG2943	transferase activity, transferring hexosyl groups
DGN11_03370	COG3275	phosphorelay sensor kinase activity
DGN11_03380	COG0181	hydroxymethylbilane synthase activity
DGN11_03410	COG1505	serine-type exopeptidase activity
DGN11_03415	COG0436	Aminotransferase
DGN11_03425	COG2832	Protein of unknown function (DUF454)
DGN11_03435	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DGN11_03445	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DGN11_03450	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DGN11_03455	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DGN11_03480	COG2226	methyltransferase
DGN11_03485	COG3300	MHYT domain
DGN11_03485	COG5001	Diguanylate cyclase
DGN11_03490	COG0308	aminopeptidase N
DGN11_03540	COG3284	Transcriptional regulator
DGN11_03545	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DGN11_03550	COG1077	Cell shape determining protein MreB Mrl
DGN11_03555	COG1792	Involved in formation and maintenance of cell shape
DGN11_03570	COG0772	Belongs to the SEDS family
DGN11_03580	COG2951	lytic endotransglycosylase activity
DGN11_03585	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DGN11_03595	COG1686	Belongs to the peptidase S11 family
DGN11_03605	COG2921	Belongs to the UPF0250 family
DGN11_03610	COG0321	lipoyl(octanoyl) transferase activity
DGN11_03615	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DGN11_03640	COG1051	belongs to the nudix hydrolase family
DGN11_03640	COG1056	cytidyltransferase-related domain
DGN11_03675	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
DGN11_03680	COG0673	inositol 2-dehydrogenase activity
DGN11_03685	COG2823	Periplasmic or secreted lipoprotein
DGN11_03690	COG4251	negative regulation of phosphorylation
DGN11_03695	COG0784	Response regulator, receiver
DGN11_03700	COG4191	Histidine kinase
DGN11_03705	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DGN11_03765	COG1459	type II secretion system
DGN11_03770	COG2165	general secretion pathway protein
DGN11_03785	COG4795	General secretion pathway protein
DGN11_03815	COG3250	beta-galactosidase activity
DGN11_03830	COG2188	Transcriptional regulator
DGN11_03840	COG1609	Transcriptional regulator
DGN11_03845	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DGN11_03850	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DGN11_03865	COG0617	tRNA 3'-terminal CCA addition
DGN11_03870	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
DGN11_03875	COG1012	belongs to the aldehyde dehydrogenase family
DGN11_03880	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DGN11_03895	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DGN11_03910	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DGN11_03935	COG2205	protein histidine kinase activity
DGN11_03965	COG3791	Glutathione-dependent formaldehyde-activating
DGN11_03980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DGN11_04005	COG0488	(ABC) transporter
DGN11_04015	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DGN11_04020	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DGN11_04030	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DGN11_04030	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DGN11_04050	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DGN11_04055	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DGN11_04060	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DGN11_04090	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DGN11_04095	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DGN11_04100	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DGN11_04105	COG2205	protein histidine kinase activity
DGN11_04110	COG0745	RESPONSE REGULATOR receiver
DGN11_04115	COG0277	FAD linked oxidase domain protein
DGN11_04120	COG1988	membrane-bound metal-dependent
DGN11_04125	COG0792	nuclease activity
DGN11_04155	COG0275	rRNA processing
DGN11_04160	COG3116	cell division
DGN11_04170	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DGN11_04175	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DGN11_04180	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DGN11_04190	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DGN11_04195	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DGN11_04200	COG1181	Belongs to the D-alanine--D-alanine ligase family
DGN11_04205	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DGN11_04220	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
DGN11_04230	COG0739	heme binding
DGN11_04235	COG0653	protein targeting
DGN11_04240	COG0494	nUDIX hydrolase
DGN11_04250	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DGN11_04265	COG3321	synthase
DGN11_04265	COG1028	Short-chain dehydrogenase reductase Sdr
DGN11_04265	COG0604	alcohol dehydrogenase
DGN11_04290	COG0366	Alpha amylase catalytic
DGN11_04330	COG2226	methyltransferase
DGN11_04335	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DGN11_04345	COG3328	transposase activity
DGN11_04350	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DGN11_04390	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DGN11_04400	COG4106	trans-aconitate 2-methyltransferase activity
DGN11_04405	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DGN11_04420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DGN11_04425	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DGN11_04435	COG0667	Aldo Keto reductase
DGN11_04445	COG4771	TonB-dependent receptor
DGN11_04465	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DGN11_04470	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DGN11_04480	COG2175	clavaminate synthase activity
DGN11_04490	COG4181	ATPase activity
DGN11_04505	COG0642	Histidine kinase
DGN11_04515	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DGN11_04535	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DGN11_04540	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DGN11_04555	COG3829	transcription factor binding
DGN11_04565	COG1116	anion transmembrane transporter activity
DGN11_04570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DGN11_04580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DGN11_04585	COG0431	NADPH-dependent FMN reductase
DGN11_04605	COG0747	negative chemotaxis
DGN11_04615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DGN11_04625	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DGN11_04630	COG2967	ApaG domain
DGN11_04635	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DGN11_04640	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DGN11_04645	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DGN11_04650	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
DGN11_04665	COG0123	including yeast histone deacetylase and acetoin utilization protein
DGN11_04670	COG2096	Adenosyltransferase
DGN11_04685	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DGN11_04690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DGN11_04720	COG3384	dioxygenase
DGN11_04725	COG0583	DNA-binding transcription factor activity
DGN11_04740	COG1024	Enoyl-CoA hydratase
DGN11_04770	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
DGN11_04795	COG0697	spore germination
DGN11_04805	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DGN11_04835	COG2197	response regulator
DGN11_04845	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DGN11_04855	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DGN11_04860	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DGN11_04870	COG0583	DNA-binding transcription factor activity
DGN11_04875	COG3634	alkyl hydroperoxide reductase activity
DGN11_04885	COG2890	protein-(glutamine-N5) methyltransferase activity
DGN11_04905	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DGN11_04905	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DGN11_04925	COG3039	Transposase
DGN11_04940	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
DGN11_04985	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DGN11_04990	COG1404	Belongs to the peptidase S8 family
DGN11_04995	COG1404	Belongs to the peptidase S8 family
DGN11_05000	COG1404	Belongs to the peptidase S8 family
DGN11_05005	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DGN11_05030	COG1295	ribonuclease BN
DGN11_05035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DGN11_05040	COG1254	Belongs to the acylphosphatase family
DGN11_05055	COG0521	Mo-molybdopterin cofactor biosynthetic process
DGN11_05065	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DGN11_05070	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DGN11_05080	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
DGN11_05085	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DGN11_05095	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DGN11_05100	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DGN11_05105	COG0193	aminoacyl-tRNA hydrolase activity
DGN11_05110	COG0012	GTP binding
DGN11_05130	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DGN11_05145	COG0250	Participates in transcription elongation, termination and antitermination
DGN11_05150	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DGN11_05155	COG0081	regulation of translation
DGN11_05160	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DGN11_05165	COG0222	ribosome binding
DGN11_05170	COG0085	RNA polymerase activity
DGN11_05175	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DGN11_05180	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DGN11_05185	COG0049	tRNA binding
DGN11_05190	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DGN11_05195	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DGN11_05200	COG0051	transcription antitermination factor activity, RNA binding
DGN11_05205	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DGN11_05210	COG0088	Forms part of the polypeptide exit tunnel
DGN11_05215	COG0089	rRNA binding
DGN11_05220	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DGN11_05225	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DGN11_05235	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DGN11_05240	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DGN11_05245	COG0255	Belongs to the universal ribosomal protein uL29 family
DGN11_05250	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DGN11_05260	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DGN11_05265	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DGN11_05275	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DGN11_05280	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DGN11_05285	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DGN11_05295	COG1841	ribosomal large subunit assembly
DGN11_05300	COG0200	Binds to the 23S rRNA
DGN11_05305	COG0201	protein transport
DGN11_05330	COG0203	ribosomal protein L17
DGN11_05335	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
DGN11_05355	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
DGN11_05370	COG0154	amidase activity
DGN11_05380	COG1217	gtp-binding protein TYPA
DGN11_05385	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DGN11_05390	COG0039	L-malate dehydrogenase activity
DGN11_05395	COG0625	glutathione transferase activity
DGN11_05410	COG1902	pentaerythritol trinitrate reductase activity
DGN11_05410	COG0446	pyridine nucleotide-disulphide oxidoreductase
DGN11_05415	COG0604	alcohol dehydrogenase
DGN11_05445	COG0156	8-amino-7-oxononanoate synthase activity
DGN11_05455	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DGN11_05460	COG4208	sulfate ABC transporter
DGN11_05465	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DGN11_05495	COG0406	alpha-ribazole phosphatase activity
DGN11_05500	COG0285	dihydrofolate synthase activity
DGN11_05520	COG2833	Protein of unknown function (DUF455)
DGN11_05540	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DGN11_05545	COG0671	phosphoesterase, PA-phosphatase related
DGN11_05550	COG0438	transferase activity, transferring glycosyl groups
DGN11_05560	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DGN11_05575	COG4783	chaperone-mediated protein folding
DGN11_05590	COG0473	3-isopropylmalate dehydrogenase activity
DGN11_05845	COG4695	Portal protein
DGN11_05870	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DGN11_05900	COG0544	peptidyl-prolyl cis-trans isomerase activity
DGN11_05910	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DGN11_05940	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DGN11_05955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DGN11_05965	COG0328	RNA-DNA hybrid ribonuclease activity
DGN11_05970	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DGN11_05975	COG0631	protein serine/threonine phosphatase activity
DGN11_05990	COG0859	PFAM glycosyl transferase family 9
DGN11_05995	COG3642	lipopolysaccharide core region biosynthetic process
DGN11_06000	COG1234	tRNA 3'-trailer cleavage
DGN11_06005	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DGN11_06015	COG0315	cyclic pyranopterin monophosphate synthase activity
DGN11_06020	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DGN11_06025	COG0314	molybdopterin synthase activity
DGN11_06060	COG3328	transposase activity
DGN11_06070	COG3328	transposase activity
DGN11_06140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DGN11_06145	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DGN11_06150	COG0537	adenosine 5'-monophosphoramidase activity
DGN11_06170	COG0714	Associated with various cellular activities
DGN11_06195	COG0424	maF-like protein
DGN11_06200	COG1399	metal-binding, possibly nucleic acid-binding protein
DGN11_06210	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DGN11_06220	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DGN11_06225	COG1028	Short-chain dehydrogenase reductase Sdr
DGN11_06240	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DGN11_06245	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DGN11_06270	COG3829	transcription factor binding
DGN11_06315	COG2373	Large extracellular alpha-helical protein
DGN11_06335	COG4953	penicillin-binding protein 1C
DGN11_06345	COG0678	peroxiredoxin activity
DGN11_06365	COG0330	HflC and HflK could
DGN11_06370	COG0330	HflC and HflK could
DGN11_06375	COG3039	Transposase
DGN11_06385	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DGN11_06395	COG1028	Short-chain dehydrogenase reductase Sdr
DGN11_06400	COG1309	transcriptional regulator
DGN11_06440	COG3039	Transposase
DGN11_06450	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DGN11_06455	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
DGN11_06465	COG3039	Transposase
DGN11_06470	COG3039	Transposase
DGN11_06480	COG3328	transposase activity
DGN11_06515	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DGN11_06525	COG3387	PFAM Glycoside hydrolase 15-related
DGN11_06530	COG1028	Short-chain dehydrogenase reductase Sdr
DGN11_06540	COG3537	Alpha-1,2-mannosidase
DGN11_06545	COG1028	Short-chain dehydrogenase reductase Sdr
DGN11_06560	COG0492	ferredoxin-NADP+ reductase activity
DGN11_06595	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DGN11_06600	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
DGN11_06605	COG2080	2 iron, 2 sulfur cluster binding
DGN11_06640	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DGN11_06655	COG0587	DNA-directed DNA polymerase activity
DGN11_06670	COG1297	OPT oligopeptide transporter protein
DGN11_06685	COG0823	Involved in the tonB-independent uptake of proteins
DGN11_06685	COG1506	peptidase
DGN11_06700	COG1917	Cupin 2, conserved barrel domain protein
DGN11_06700	COG2207	Transcriptional regulator
DGN11_06730	COG0753	catalase activity
DGN11_06735	COG0656	L-ascorbic acid biosynthetic process
DGN11_06745	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DGN11_06745	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DGN11_06750	COG2814	Major facilitator Superfamily
DGN11_06765	COG2194	sulfuric ester hydrolase activity
DGN11_06780	COG0745	RESPONSE REGULATOR receiver
DGN11_06785	COG0642	Histidine kinase
DGN11_06795	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
DGN11_06800	COG2894	cell division
DGN11_06805	COG0850	regulation of cytokinetic process
DGN11_06820	COG4585	Histidine kinase
DGN11_06825	COG2197	response regulator
DGN11_06840	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
DGN11_06870	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DGN11_06880	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
DGN11_06900	COG1946	Acyl-CoA thioesterase
DGN11_06915	COG0824	Thioesterase
DGN11_06920	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DGN11_06925	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DGN11_06930	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DGN11_06935	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DGN11_06940	COG0268	Binds directly to 16S ribosomal RNA
DGN11_06950	COG0196	riboflavin kinase activity
DGN11_06955	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DGN11_06960	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DGN11_06965	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DGN11_06985	COG3039	Transposase
DGN11_06990	COG3328	transposase activity
DGN11_07000	COG3039	Transposase
DGN11_07020	COG3328	transposase activity
DGN11_07055	COG0189	ligase activity
DGN11_07065	COG0745	RESPONSE REGULATOR receiver
DGN11_07080	COG3039	Transposase
DGN11_07090	COG3328	transposase activity
DGN11_07095	COG0237	dephospho-CoA kinase activity
DGN11_07100	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DGN11_07105	COG1459	type II secretion system
DGN11_07140	COG0045	succinate-CoA ligase (ADP-forming) activity
DGN11_07145	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DGN11_07160	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DGN11_07160	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DGN11_07170	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DGN11_07175	COG0564	pseudouridine synthase activity
DGN11_07190	COG3011	Protein conserved in bacteria
DGN11_07195	COG0840	transmembrane signaling receptor activity
DGN11_07215	COG3387	PFAM Glycoside hydrolase 15-related
DGN11_07220	COG1877	trehalose-phosphatase activity
DGN11_07260	COG2827	Endonuclease containing a URI domain
DGN11_07265	COG4771	TonB-dependent receptor
DGN11_07270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DGN11_07275	COG0667	Aldo Keto reductase
DGN11_07280	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DGN11_07285	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DGN11_07290	COG1116	anion transmembrane transporter activity
DGN11_07295	COG0542	response to heat
DGN11_07300	COG4206	TonB-dependent receptor
DGN11_07325	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DGN11_07335	COG1492	cobalamin metabolic process
DGN11_07345	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DGN11_07370	COG0019	diaminopimelate decarboxylase activity
DGN11_07385	COG4264	IucA IucC family
DGN11_07395	COG4772	TonB-dependent receptor
DGN11_07405	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DGN11_07405	COG4651	solute:proton antiporter activity
DGN11_07445	COG0488	(ABC) transporter
DGN11_07485	COG0477	Major facilitator Superfamily
DGN11_07500	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DGN11_07515	COG0217	transcriptional regulatory protein
DGN11_07520	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DGN11_07525	COG0632	four-way junction helicase activity
DGN11_07530	COG3158	transport of potassium into the cell
DGN11_07540	COG2255	four-way junction helicase activity
DGN11_07545	COG0824	Thioesterase
DGN11_07555	COG0848	biopolymer transport protein
DGN11_07565	COG0823	Involved in the tonB-independent uptake of proteins
DGN11_07570	COG2885	chlorophyll binding
DGN11_07580	COG0602	queuosine metabolic process
DGN11_07590	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DGN11_07595	COG3920	Histidine kinase
DGN11_07615	COG0840	transmembrane signaling receptor activity
DGN11_07655	COG0514	ATP-dependent DNA helicase (RecQ)
DGN11_07660	COG0783	Belongs to the Dps family
DGN11_07665	COG1643	Atp-dependent helicase
DGN11_07675	COG0837	glucose binding
DGN11_07690	COG0535	radical SAM domain protein
DGN11_07695	COG0535	radical SAM domain protein
DGN11_07700	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
DGN11_07705	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DGN11_07715	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DGN11_07735	COG1215	transferase activity, transferring glycosyl groups
DGN11_07740	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DGN11_07750	COG1199	ATP-dependent helicase activity
DGN11_07760	COG1397	ADP-ribosylglycohydrolase
DGN11_07770	COG0189	ligase activity
DGN11_07785	COG0835	chemotaxis
DGN11_07790	COG0840	transmembrane signaling receptor activity
DGN11_07795	COG0643	Histidine kinase
DGN11_07795	COG0784	Response regulator, receiver
DGN11_07795	COG2198	Histidine kinase
DGN11_07820	COG1446	asparaginase
DGN11_07825	COG3142	Participates in the control of copper homeostasis
DGN11_07865	COG3537	Alpha-1,2-mannosidase
DGN11_07875	COG1486	melibiose metabolic process
DGN11_07885	COG0531	amino acid
DGN11_07905	COG1472	Belongs to the glycosyl hydrolase 3 family
DGN11_07920	COG3858	chitin binding
DGN11_07920	COG1388	LysM domain
DGN11_07935	COG0837	glucose binding
DGN11_07940	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DGN11_07950	COG0494	nUDIX hydrolase
DGN11_07955	COG1218	3'(2'),5'-bisphosphate nucleotidase
DGN11_07960	COG3956	TIGRFAM MazG family protein
DGN11_07965	COG1742	UPF0060 membrane protein
DGN11_07980	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DGN11_07985	COG0509	glycine decarboxylation via glycine cleavage system
DGN11_08005	COG3328	transposase activity
DGN11_08030	COG1960	acyl-CoA dehydrogenase activity
DGN11_08040	COG1309	transcriptional regulator
DGN11_08045	COG3039	Transposase
DGN11_08055	COG3328	transposase activity
DGN11_08060	COG3039	Transposase
DGN11_08065	COG4771	TonB-dependent receptor
DGN11_08075	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DGN11_08080	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DGN11_08085	COG0463	Glycosyl transferase, family 2
DGN11_08090	COG0516	GMP reductase activity
DGN11_08090	COG0517	IMP dehydrogenase activity
DGN11_08095	COG2982	Protein involved in outer membrane biogenesis
DGN11_08100	COG1272	protein, Hemolysin III
DGN11_08105	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DGN11_08110	COG0739	heme binding
DGN11_08115	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DGN11_08120	COG0626	cystathionine gamma-synthase activity
DGN11_08125	COG0527	aspartate kinase activity
DGN11_08125	COG0460	homoserine dehydrogenase
DGN11_08140	COG1760	l-serine dehydratase
DGN11_08160	COG2353	YceI-like domain
DGN11_08165	COG0784	Response regulator, receiver
DGN11_08165	COG2198	Histidine kinase
DGN11_08165	COG2205	protein histidine kinase activity
DGN11_08185	COG2814	Major facilitator Superfamily
DGN11_08190	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DGN11_08200	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DGN11_08205	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DGN11_08210	COG0259	pyridoxamine-phosphate oxidase activity
DGN11_08220	COG1842	Phage shock protein A
DGN11_08245	COG0754	glutathionylspermidine amidase activity
DGN11_08260	COG2814	Major facilitator Superfamily
DGN11_08370	COG0531	amino acid
DGN11_08375	COG2197	response regulator
DGN11_08400	COG3328	transposase activity
DGN11_08410	COG1113	amino acid transport
DGN11_08420	COG1271	oxidase subunit
DGN11_08425	COG1294	oxidase, subunit
DGN11_08435	COG2239	Acts as a magnesium transporter
DGN11_08445	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DGN11_08450	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DGN11_08460	COG1660	Displays ATPase and GTPase activities
DGN11_08465	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DGN11_08470	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DGN11_08485	COG1137	ATPase activity
DGN11_08490	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
DGN11_08500	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DGN11_08510	COG0271	Belongs to the BolA IbaG family
DGN11_08515	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DGN11_08535	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DGN11_08545	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DGN11_08555	COG0628	permease
DGN11_08570	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DGN11_08575	COG3178	'Phosphotransferase
DGN11_08590	COG1555	photosystem II stabilization
DGN11_08600	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DGN11_08605	COG1477	protein flavinylation
DGN11_08630	COG3128	pkhd-type hydroxylase
DGN11_08635	COG4774	siderophore transport
DGN11_08640	COG2146	nitrite reductase [NAD(P)H] activity
DGN11_08650	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DGN11_08655	COG0719	Fe-S assembly protein
DGN11_08660	COG0396	ATPase activity
DGN11_08665	COG0719	Fe-S assembly protein
DGN11_08670	COG1959	2 iron, 2 sulfur cluster binding
DGN11_08680	COG0693	protein deglycase activity
DGN11_08700	COG0739	heme binding
DGN11_08715	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DGN11_08740	COG0519	Catalyzes the synthesis of GMP from XMP
DGN11_08750	COG1678	Uncharacterized ACR, COG1678
DGN11_08755	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DGN11_08760	COG0540	Belongs to the ATCase OTCase family
DGN11_08765	COG1764	response to oxidative stress
DGN11_08775	COG0384	phenazine biosynthesis protein PhzF
DGN11_08780	COG0384	phenazine biosynthesis protein PhzF
DGN11_08785	COG0527	aspartate kinase activity
DGN11_08800	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DGN11_08815	COG0142	geranyltranstransferase activity
DGN11_08820	COG0629	single-stranded DNA binding
DGN11_08825	COG2203	Gaf domain
DGN11_08825	COG3706	GGDEF domain
DGN11_08825	COG4251	negative regulation of phosphorylation
DGN11_08825	COG5001	Diguanylate cyclase
DGN11_08830	COG3321	synthase
DGN11_08830	COG0604	alcohol dehydrogenase
DGN11_08830	COG1028	Short-chain dehydrogenase reductase Sdr
DGN11_08835	COG2080	2 iron, 2 sulfur cluster binding
DGN11_08840	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
DGN11_08845	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DGN11_08850	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DGN11_08895	COG2879	small protein
DGN11_08900	COG1966	Carbon starvation protein
DGN11_08905	COG1741	Belongs to the pirin family
DGN11_08920	COG1741	Belongs to the pirin family
DGN11_08925	COG3328	transposase activity
DGN11_08935	COG1515	deoxyribonuclease V activity
DGN11_08940	COG0588	phosphoglycerate mutase activity
DGN11_08950	COG3590	peptidase
DGN11_08955	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DGN11_08960	COG2201	protein-glutamate methylesterase activity
DGN11_08965	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DGN11_08970	COG2200	EAL domain
DGN11_08970	COG2202	Pas domain
DGN11_08970	COG2199	diguanylate cyclase activity
DGN11_08975	COG0835	chemotaxis
DGN11_08980	COG0840	transmembrane signaling receptor activity
DGN11_08985	COG0643	Histidine kinase
DGN11_08985	COG2198	Histidine kinase
DGN11_08995	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DGN11_09010	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
DGN11_09015	COG0745	RESPONSE REGULATOR receiver
DGN11_09020	COG2205	protein histidine kinase activity
DGN11_09030	COG4452	Inner membrane protein CreD
DGN11_09055	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DGN11_09060	COG0735	belongs to the Fur family
DGN11_09075	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DGN11_09085	COG1309	transcriptional regulator
DGN11_09095	COG2207	Transcriptional regulator
DGN11_09105	COG0583	DNA-binding transcription factor activity
DGN11_09110	COG2814	Major facilitator Superfamily
DGN11_09115	COG0667	Aldo Keto reductase
DGN11_09220	COG1595	DNA-templated transcription, initiation
DGN11_09230	COG5002	protein histidine kinase activity
DGN11_09230	COG5001	Diguanylate cyclase
DGN11_09235	COG1187	pseudouridine synthase activity
DGN11_09255	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DGN11_09265	COG0475	glutathione-regulated potassium exporter activity
DGN11_09270	COG5002	protein histidine kinase activity
DGN11_09270	COG5000	phosphorelay sensor kinase activity
DGN11_09275	COG0745	RESPONSE REGULATOR receiver
DGN11_09280	COG1538	Outer membrane efflux protein
DGN11_09305	COG1132	(ABC) transporter
DGN11_09350	COG2155	Conserved Protein
DGN11_09390	COG3118	belongs to the thioredoxin family
DGN11_09400	COG0495	leucyl-tRNA aminoacylation
DGN11_09415	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DGN11_09430	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DGN11_09445	COG2968	Membrane
DGN11_09450	COG0424	maF-like protein
DGN11_09460	COG3164	Protein of unknown function
DGN11_09470	COG0312	modulator of DNA gyrase
DGN11_09475	COG3028	Belongs to the UPF0307 family
DGN11_09480	COG0312	modulator of DNA gyrase
DGN11_09490	COG4104	PAAR repeat-containing protein
DGN11_09495	COG0142	geranyltranstransferase activity
DGN11_09500	COG1722	exodeoxyribonuclease VII activity
DGN11_09505	COG0037	tRNA processing
DGN11_09515	COG1785	Belongs to the alkaline phosphatase family
DGN11_09520	COG1301	dicarboxylic acid transport
DGN11_09525	COG4106	trans-aconitate 2-methyltransferase activity
DGN11_09535	COG0791	NLP P60 protein
DGN11_09540	COG0791	NLP P60 protein
DGN11_09545	COG1047	Peptidyl-prolyl cis-trans
DGN11_09550	COG2311	Membrane
DGN11_09555	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DGN11_09560	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DGN11_09580	COG3590	peptidase
DGN11_09585	COG3590	peptidase
DGN11_09595	COG3039	Transposase
DGN11_09610	COG0489	protein tyrosine kinase activity
DGN11_09620	COG0717	Belongs to the dCTP deaminase family
DGN11_09675	COG3328	transposase activity
DGN11_09685	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DGN11_09690	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DGN11_09705	COG0494	nUDIX hydrolase
DGN11_09710	COG0433	COG0433 Predicted ATPase
DGN11_09725	COG0688	phosphatidylethanolamine metabolic process
DGN11_09735	COG2890	protein-(glutamine-N5) methyltransferase activity
DGN11_09740	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DGN11_09745	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DGN11_09750	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DGN11_09765	COG0101	tRNA pseudouridine synthase activity
DGN11_09770	COG0135	phosphoribosylanthranilate isomerase activity
DGN11_09780	COG0133	tryptophan synthase activity
DGN11_09790	COG0159	tryptophan synthase activity
DGN11_09795	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DGN11_09800	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DGN11_09830	COG3039	Transposase
DGN11_09835	COG0300	oxidoreductase activity
DGN11_09840	COG0149	triose-phosphate isomerase activity
DGN11_09855	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DGN11_09860	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DGN11_09865	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DGN11_09870	COG0649	NAD binding
DGN11_09875	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
DGN11_09880	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DGN11_09890	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DGN11_09895	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DGN11_09920	COG1007	ATP synthesis coupled electron transport
DGN11_09930	COG0779	Required for maturation of 30S ribosomal subunits
DGN11_09935	COG0195	Participates in both transcription termination and antitermination
DGN11_09940	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DGN11_09945	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DGN11_09950	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DGN11_09955	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DGN11_09960	COG1185	polyribonucleotide nucleotidyltransferase activity
DGN11_09995	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DGN11_10005	COG2095	MarC family integral membrane protein
DGN11_10020	COG1611	Belongs to the LOG family
DGN11_10065	COG3328	transposase activity
DGN11_10075	COG0556	nucleotide-excision repair
DGN11_10090	COG3505	Type IV secretory pathway VirD4
DGN11_10110	COG2948	multi-organism process
DGN11_10130	COG3702	type iv secretory pathway
DGN11_10165	COG3328	transposase activity
DGN11_10180	COG3328	transposase activity
DGN11_10190	COG2190	(PTS) system
DGN11_10190	COG2211	Major facilitator Superfamily
DGN11_10205	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DGN11_10210	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DGN11_10225	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DGN11_10230	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DGN11_10230	COG0072	phenylalanine-tRNA ligase activity
DGN11_10280	COG0438	transferase activity, transferring glycosyl groups
DGN11_10285	COG0438	transferase activity, transferring glycosyl groups
DGN11_10295	COG0438	transferase activity, transferring glycosyl groups
DGN11_10320	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DGN11_10325	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DGN11_10330	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DGN11_10350	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DGN11_10360	COG1960	acyl-CoA dehydrogenase activity
DGN11_10370	COG3040	lipid binding
DGN11_10380	COG0582	viral genome integration into host DNA
DGN11_10390	COG3039	Transposase
DGN11_10405	COG3039	Transposase
DGN11_10420	COG0322	excinuclease ABC activity
DGN11_10440	COG0784	Response regulator, receiver
DGN11_10440	COG4191	Histidine kinase
DGN11_10445	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
DGN11_10450	COG1194	a g-specific adenine glycosylase
DGN11_10460	COG0552	protein localization to endoplasmic reticulum
DGN11_10470	COG3938	Belongs to the proline racemase family
DGN11_10475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DGN11_10490	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DGN11_10500	COG0006	proline dipeptidase activity
DGN11_10515	COG0531	amino acid
DGN11_10605	COG3039	Transposase
DGN11_10615	COG3039	Transposase
DGN11_10620	COG0326	Molecular chaperone. Has ATPase activity
DGN11_10625	COG0742	ribosomal rna small subunit methyltransferase
DGN11_10630	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DGN11_10645	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DGN11_10650	COG0405	Gamma-glutamyltransferase
DGN11_10655	COG3291	Pkd domain containing protein
DGN11_10660	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DGN11_10700	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DGN11_10705	COG0343	queuine tRNA-ribosyltransferase activity
DGN11_10710	COG1862	Preprotein translocase
DGN11_10720	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DGN11_10745	COG3328	transposase activity
DGN11_10760	COG3328	transposase activity
DGN11_10795	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DGN11_10795	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DGN11_10800	COG1105	Belongs to the carbohydrate kinase PfkB family
DGN11_10805	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DGN11_10805	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DGN11_10810	COG1609	Transcriptional regulator
DGN11_10815	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DGN11_10820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DGN11_10830	COG2902	Dehydrogenase
DGN11_10840	COG3321	synthase
DGN11_10840	COG0604	alcohol dehydrogenase
DGN11_10850	COG1902	pentaerythritol trinitrate reductase activity
DGN11_10860	COG0300	oxidoreductase activity
DGN11_10870	COG3039	Transposase
DGN11_10875	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DGN11_10885	COG1705	Flagellar rod assembly protein muramidase FlgJ
DGN11_10885	COG3951	Flagellar rod assembly protein muramidase FlgJ
DGN11_10890	COG1706	bacterial-type flagellum-dependent cell motility
DGN11_10895	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
DGN11_10905	COG4787	bacterial-type flagellum-dependent cell motility
DGN11_10915	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DGN11_10920	COG1558	bacterial-type flagellum-dependent cell motility
DGN11_10930	COG0835	chemotaxis
DGN11_10930	COG0784	Response regulator, receiver
DGN11_10950	COG5002	protein histidine kinase activity
DGN11_10980	COG2915	High frequency lysogenization protein hflD homolog
DGN11_10985	COG0482	sulfurtransferase activity
DGN11_11000	COG0542	response to heat
DGN11_11010	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
DGN11_11020	COG0492	ferredoxin-NADP+ reductase activity
DGN11_11025	COG1674	ftsk spoiiie
DGN11_11035	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DGN11_11045	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DGN11_11050	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DGN11_11060	COG0183	Belongs to the thiolase family
DGN11_11065	COG1024	Enoyl-CoA hydratase
DGN11_11065	COG1250	3-hydroxyacyl-CoA dehydrogenase
DGN11_11080	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DGN11_11090	COG1426	Protein conserved in bacteria
DGN11_11100	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DGN11_11105	COG1160	GTP binding
DGN11_11110	COG0303	'Molybdopterin
DGN11_11115	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DGN11_11150	COG0708	Exodeoxyribonuclease III
DGN11_11160	COG0303	'Molybdopterin
DGN11_11165	COG0746	molybdenum cofactor guanylyltransferase activity
DGN11_11195	COG1914	H( )-stimulated, divalent metal cation uptake system
DGN11_11210	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
DGN11_11215	COG0668	transmembrane transport
DGN11_11225	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DGN11_11240	COG1028	Short-chain dehydrogenase reductase Sdr
DGN11_11245	COG1183	phosphatidylcholine synthase activity
DGN11_11255	COG3243	poly(R)-hydroxyalkanoic acid synthase
DGN11_11270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DGN11_11270	COG0723	plastoquinol--plastocyanin reductase activity
DGN11_11280	COG2183	response to ionizing radiation
DGN11_11285	COG0784	Response regulator, receiver
DGN11_11285	COG2205	protein histidine kinase activity
DGN11_11350	COG0800	Aldolase
DGN11_11355	COG0129	dihydroxy-acid dehydratase activity
DGN11_11360	COG0363	glucosamine-6-phosphate deaminase activity
DGN11_11365	COG0837	glucose binding
DGN11_11370	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DGN11_11380	COG0354	folic acid binding
DGN11_11395	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
DGN11_11410	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DGN11_11415	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
DGN11_11425	COG4591	ABC-type transport system involved in lipoprotein release permease component
DGN11_11430	COG1136	(ABC) transporter
DGN11_11445	COG0811	peptide transport
DGN11_11450	COG0848	biopolymer transport protein
DGN11_11455	COG1132	(ABC) transporter
DGN11_11460	COG1663	tetraacyldisaccharide 4'-kinase activity
DGN11_11465	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
DGN11_11470	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DGN11_11480	COG0322	excinuclease ABC activity
DGN11_11485	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DGN11_11510	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
DGN11_11530	COG1054	Belongs to the UPF0176 family
DGN11_11540	COG1530	ribonuclease E activity
DGN11_11550	COG3064	Membrane
DGN11_11555	COG0428	transporter
DGN11_11565	COG2154	pterin-4-alpha-carbinolamine dehydratase
DGN11_11570	COG0316	Belongs to the HesB IscA family
DGN11_11570	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
DGN11_11630	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
DGN11_11635	COG1028	Short-chain dehydrogenase reductase Sdr
DGN11_11665	COG3328	transposase activity
DGN11_11675	COG1136	(ABC) transporter
DGN11_11680	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DGN11_11685	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DGN11_11685	COG1028	Short-chain dehydrogenase reductase Sdr
DGN11_11685	COG3321	synthase
DGN11_11685	COG4221	oxidoreductase activity
DGN11_11690	COG3321	synthase
DGN11_11690	COG1028	Short-chain dehydrogenase reductase Sdr
DGN11_11690	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DGN11_11690	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DGN11_11690	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DGN11_11695	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DGN11_11695	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DGN11_11695	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DGN11_11695	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DGN11_11695	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DGN11_11695	COG3321	synthase
DGN11_11695	COG1028	Short-chain dehydrogenase reductase Sdr
DGN11_11695	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DGN11_11695	COG1028	Short-chain dehydrogenase reductase Sdr
DGN11_11695	COG3321	synthase
DGN11_11705	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DGN11_11740	COG3039	Transposase
DGN11_11750	COG0583	DNA-binding transcription factor activity
DGN11_11785	COG3220	belongs to the UPF0276 family
DGN11_11810	COG3920	Histidine kinase
DGN11_11850	COG3279	Response regulator of the LytR AlgR family
DGN11_11855	COG3275	phosphorelay sensor kinase activity
DGN11_11895	COG4566	intracellular signal transduction
DGN11_11905	COG5001	Diguanylate cyclase
DGN11_11925	COG3685	Protein conserved in bacteria
DGN11_11945	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DGN11_11945	COG1648	precorrin-2 dehydrogenase activity
DGN11_11960	COG2814	Major facilitator Superfamily
DGN11_11975	COG1335	isochorismatase
DGN11_11990	COG2197	response regulator
DGN11_12005	COG0583	DNA-binding transcription factor activity
DGN11_12010	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DGN11_12020	COG0519	Catalyzes the synthesis of GMP from XMP
DGN11_12020	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DGN11_12030	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DGN11_12045	COG0475	glutathione-regulated potassium exporter activity
DGN11_12045	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DGN11_12055	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DGN11_12065	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DGN11_12070	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
DGN11_12080	COG0776	regulation of translation
DGN11_12085	COG0539	negative regulation of cytoplasmic translation
DGN11_12090	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DGN11_12110	COG2957	Belongs to the agmatine deiminase family
DGN11_12115	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DGN11_12140	COG0395	ABC-type sugar transport system, permease component
DGN11_12145	COG1175	transmembrane transport
DGN11_12175	COG2350	Protein conserved in bacteria
DGN11_12180	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DGN11_12185	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DGN11_12190	COG1187	pseudouridine synthase activity
DGN11_12215	COG0436	Aminotransferase
DGN11_12220	COG4133	protoheme IX ABC transporter activity
DGN11_12240	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
DGN11_12245	COG1138	Cytochrome C-type biogenesis protein
DGN11_12265	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DGN11_12270	COG1278	Cold shock
DGN11_12275	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DGN11_12280	COG4988	ABC transporter
DGN11_12290	COG1294	oxidase, subunit
DGN11_12320	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DGN11_12325	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DGN11_12335	COG0165	Argininosuccinate lyase
DGN11_12340	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DGN11_12350	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DGN11_12355	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DGN11_12365	COG0137	argininosuccinate synthase activity
DGN11_12370	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DGN11_12380	COG0215	cysteine-tRNA ligase activity
DGN11_12385	COG2166	iron-sulfur cluster assembly
DGN11_12400	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DGN11_12405	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DGN11_12425	COG4302	ethanolamine ammonia-lyase activity
DGN11_12490	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DGN11_12495	COG0402	S-adenosylhomocysteine deaminase activity
DGN11_12505	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DGN11_12510	COG1509	lysine 2,3-aminomutase activity
DGN11_12515	COG3300	MHYT domain
DGN11_12515	COG5001	Diguanylate cyclase
DGN11_12530	COG0483	inositol monophosphate 1-phosphatase activity
DGN11_12535	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DGN11_12555	COG0488	(ABC) transporter
DGN11_12560	COG0513	Belongs to the DEAD box helicase family
DGN11_12565	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DGN11_12570	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
DGN11_12580	COG0625	glutathione transferase activity
DGN11_12590	COG4681	YaeQ
DGN11_12595	COG2081	HI0933 family
DGN11_12605	COG0501	Belongs to the peptidase M48B family
DGN11_12610	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DGN11_12615	COG1028	Short-chain dehydrogenase reductase Sdr
DGN11_12640	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DGN11_12645	COG0860	N-Acetylmuramoyl-L-alanine amidase
DGN11_12650	COG0802	atpase or kinase
DGN11_12655	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DGN11_12655	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DGN11_12660	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DGN11_12665	COG1570	exodeoxyribonuclease VII activity
DGN11_12680	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DGN11_12725	COG0835	chemotaxis
DGN11_12730	COG0840	transmembrane signaling receptor activity
DGN11_12735	COG2094	Belongs to the DNA glycosylase MPG family
DGN11_12740	COG1201	RNA secondary structure unwinding
DGN11_12760	COG2969	positive regulation of protein catabolic process
DGN11_12765	COG0625	glutathione transferase activity
DGN11_12770	COG2857	Cytochrome c1
DGN11_12775	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DGN11_12780	COG0723	plastoquinol--plastocyanin reductase activity
DGN11_12790	COG0741	lytic transglycosylase activity
DGN11_12805	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DGN11_12810	COG1702	phosphate starvation-inducible protein PhoH
DGN11_12820	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DGN11_12830	COG4535	Mg2 and Co2 transporter CorC
DGN11_12845	COG1012	belongs to the aldehyde dehydrogenase family
DGN11_12850	COG1177	transmembrane transport
DGN11_12855	COG1176	ABC-type spermidine putrescine transport system, permease component I
DGN11_12885	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DGN11_12900	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DGN11_12905	COG0174	glutamine synthetase
DGN11_12910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DGN11_12920	COG2703	oxygen carrier activity
DGN11_12925	COG0477	Major facilitator Superfamily
DGN11_12940	COG0243	molybdopterin cofactor binding
DGN11_12945	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DGN11_12950	COG2223	nitrite transmembrane transporter activity
DGN11_12965	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DGN11_12975	COG2733	membrane
DGN11_12980	COG2205	protein histidine kinase activity
DGN11_12980	COG5002	protein histidine kinase activity
DGN11_12980	COG0784	Response regulator, receiver
DGN11_12995	COG0477	Major facilitator Superfamily
DGN11_13010	COG3039	Transposase
DGN11_13025	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
DGN11_13055	COG2201	protein-glutamate methylesterase activity
DGN11_13075	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DGN11_13080	COG1028	Short-chain dehydrogenase reductase Sdr
DGN11_13085	COG1028	Short-chain dehydrogenase reductase Sdr
DGN11_13115	COG3039	Transposase
DGN11_13130	COG1677	Flagellar hook-basal body complex protein FliE
DGN11_13180	COG3190	flagellar
DGN11_13200	COG1684	flagellar biosynthetic protein fliR
DGN11_13230	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DGN11_13265	COG0784	Response regulator, receiver
DGN11_13265	COG2198	Histidine kinase
DGN11_13265	COG0643	Histidine kinase
DGN11_13275	COG3328	transposase activity
DGN11_13295	COG3039	Transposase
DGN11_13340	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DGN11_13345	COG1360	Flagellar Motor Protein
DGN11_13355	COG0835	chemotaxis
DGN11_13365	COG0745	RESPONSE REGULATOR receiver
DGN11_13375	COG0840	transmembrane signaling receptor activity
DGN11_13395	COG0840	transmembrane signaling receptor activity
DGN11_13400	COG0840	transmembrane signaling receptor activity
DGN11_13405	COG0840	transmembrane signaling receptor activity
DGN11_13415	COG0840	transmembrane signaling receptor activity
DGN11_13420	COG0840	transmembrane signaling receptor activity
DGN11_13425	COG0840	transmembrane signaling receptor activity
DGN11_13430	COG0840	transmembrane signaling receptor activity
DGN11_13465	COG0835	chemotaxis
DGN11_13480	COG0840	transmembrane signaling receptor activity
DGN11_13490	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
DGN11_13495	COG2201	protein-glutamate methylesterase activity
DGN11_13505	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DGN11_13535	COG0318	PFAM AMP-dependent synthetase and ligase
DGN11_13540	COG1024	Enoyl-CoA hydratase
DGN11_13545	COG2198	Histidine kinase
DGN11_13545	COG0784	Response regulator, receiver
DGN11_13545	COG2205	protein histidine kinase activity
DGN11_13550	COG0784	Response regulator, receiver
DGN11_13550	COG2198	Histidine kinase
DGN11_13550	COG2205	protein histidine kinase activity
DGN11_13560	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DGN11_13570	COG3279	Response regulator of the LytR AlgR family
DGN11_13580	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DGN11_13590	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DGN11_13595	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DGN11_13605	COG0505	Belongs to the CarA family
DGN11_13610	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DGN11_13615	COG2258	MOSC domain
DGN11_13620	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DGN11_13665	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DGN11_13685	COG0277	FAD linked oxidase domain protein
DGN11_13690	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DGN11_13700	COG0531	amino acid
DGN11_13705	COG0531	amino acid
DGN11_13710	COG0235	Class ii aldolase
DGN11_13715	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
DGN11_13720	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
DGN11_13735	COG0140	phosphoribosyl-ATP diphosphatase activity
DGN11_13735	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DGN11_13740	COG0107	imidazoleglycerol-phosphate synthase activity
DGN11_13745	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DGN11_13750	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DGN11_13755	COG0131	Imidazoleglycerol-phosphate dehydratase
DGN11_13755	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DGN11_13760	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DGN11_13765	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DGN11_13770	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DGN11_13780	COG0124	histidyl-tRNA synthetase
DGN11_13785	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DGN11_13825	COG3328	transposase activity
DGN11_13830	COG3328	transposase activity
DGN11_13855	COG3039	Transposase
DGN11_13865	COG3039	Transposase
DGN11_13870	COG3039	Transposase
DGN11_13875	COG3210	domain, Protein
DGN11_13910	COG1649	PFAM Uncharacterised BCR, COG1649
DGN11_13910	COG0726	polysaccharide deacetylase
DGN11_13915	COG1215	transferase activity, transferring glycosyl groups
DGN11_13930	COG1012	belongs to the aldehyde dehydrogenase family
DGN11_13945	COG0167	dihydroorotate dehydrogenase activity
DGN11_13950	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DGN11_13955	COG0697	spore germination
DGN11_13965	COG1794	racemase activity, acting on amino acids and derivatives
DGN11_13985	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DGN11_13995	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
DGN11_14000	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DGN11_14005	COG2203	Gaf domain
DGN11_14005	COG5001	Diguanylate cyclase
DGN11_14005	COG3706	GGDEF domain
DGN11_14005	COG4251	negative regulation of phosphorylation
DGN11_14020	COG1472	Belongs to the glycosyl hydrolase 3 family
DGN11_14045	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DGN11_14050	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DGN11_14055	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DGN11_14075	COG1469	GTP cyclohydrolase I activity
DGN11_14080	COG0860	N-Acetylmuramoyl-L-alanine amidase
DGN11_14090	COG3328	transposase activity
DGN11_14110	COG2115	Belongs to the xylose isomerase family
DGN11_14115	COG1070	Carbohydrate kinase
DGN11_14125	COG1501	Belongs to the glycosyl hydrolase 31 family
DGN11_14165	COG0800	Aldolase
DGN11_14170	COG4948	Mandelate Racemase Muconate Lactonizing
DGN11_14180	COG3734	2-keto-3-deoxy-galactonokinase
DGN11_14185	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DGN11_14195	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DGN11_14210	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DGN11_14215	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DGN11_14230	COG0351	phosphomethylpyrimidine kinase
DGN11_14255	COG0583	DNA-binding transcription factor activity
DGN11_14260	COG1741	Belongs to the pirin family
DGN11_14280	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
DGN11_14285	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DGN11_14290	COG2137	regulation of response to DNA damage stimulus
DGN11_14300	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DGN11_14305	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DGN11_14315	COG1546	Belongs to the CinA family
DGN11_14320	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DGN11_14330	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DGN11_14335	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DGN11_14345	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
DGN11_14350	COG1534	Rna-binding protein
DGN11_14365	COG1238	metal cluster binding
DGN11_14370	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DGN11_14375	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
DGN11_14380	COG2840	Smr protein MutS2
DGN11_14385	COG0585	pseudouridine synthase activity
DGN11_14390	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DGN11_14395	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DGN11_14400	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DGN11_14405	COG0148	phosphopyruvate hydratase activity
DGN11_14420	COG0504	CTP synthase activity
DGN11_14450	COG0306	phosphate transporter
DGN11_14465	COG1253	flavin adenine dinucleotide binding
DGN11_14475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DGN11_14485	COG2271	Major facilitator Superfamily
DGN11_14495	COG1136	(ABC) transporter
DGN11_14520	COG2264	protein methyltransferase activity
DGN11_14550	COG2244	polysaccharide biosynthetic process
DGN11_14605	COG1595	DNA-templated transcription, initiation
DGN11_14620	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DGN11_14630	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
DGN11_14640	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DGN11_14655	COG0784	Response regulator, receiver
DGN11_14655	COG4191	Histidine kinase
DGN11_14660	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
DGN11_14695	COG0840	transmembrane signaling receptor activity
DGN11_14715	COG3328	transposase activity
DGN11_14735	COG0583	DNA-binding transcription factor activity
DGN11_14740	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DGN11_14745	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DGN11_14765	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DGN11_14770	COG1605	Chorismate mutase
DGN11_14770	COG0077	Prephenate dehydratase
DGN11_14775	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DGN11_14780	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DGN11_14785	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
DGN11_14825	COG1228	amidohydrolase
DGN11_14830	COG2986	histidine ammonia-lyase
DGN11_14840	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DGN11_14850	COG4993	Dehydrogenase
DGN11_14860	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DGN11_14875	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
DGN11_14880	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DGN11_14885	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DGN11_14895	COG3115	cell septum assembly
DGN11_14910	COG0359	binds to the 23S rRNA
DGN11_14915	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DGN11_14920	COG0360	Binds together with S18 to 16S ribosomal RNA
DGN11_14925	COG0316	Belongs to the HesB IscA family
DGN11_14935	COG0017	Asparaginyl-tRNA synthetase
DGN11_14970	COG3039	Transposase
DGN11_15020	COG0288	reversible hydration of carbon dioxide
DGN11_15025	COG0662	Cupin 2, conserved barrel domain protein
DGN11_15035	COG3844	kynureninase activity
DGN11_15040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DGN11_15045	COG2925	Exonuclease
DGN11_15070	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DGN11_15075	COG0116	Belongs to the methyltransferase superfamily
DGN11_15075	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DGN11_15085	COG0488	(ABC) transporter
DGN11_15120	COG0494	nUDIX hydrolase
DGN11_15130	COG1024	Enoyl-CoA hydratase
DGN11_15140	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DGN11_15145	COG0659	secondary active sulfate transmembrane transporter activity
DGN11_15170	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DGN11_15175	COG0573	inorganic phosphate transmembrane transporter activity
DGN11_15180	COG0581	inorganic phosphate transmembrane transporter activity
DGN11_15185	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DGN11_15190	COG0704	Plays a role in the regulation of phosphate uptake
DGN11_15200	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DGN11_15210	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DGN11_15220	COG0557	exoribonuclease II activity
DGN11_15240	COG1960	acyl-CoA dehydrogenase activity
DGN11_15250	COG1960	acyl-CoA dehydrogenase activity
DGN11_15255	COG2226	methyltransferase
DGN11_15260	COG0646	methionine synthase
DGN11_15260	COG1410	methionine synthase
DGN11_15265	COG0646	methionine synthase
DGN11_15265	COG1410	methionine synthase
DGN11_15275	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DGN11_15300	COG2900	Belongs to the SlyX family
DGN11_15315	COG0386	Belongs to the glutathione peroxidase family
DGN11_15325	COG1725	Transcriptional regulator
DGN11_15330	COG1131	(ABC) transporter
DGN11_15365	COG1253	flavin adenine dinucleotide binding
DGN11_15390	COG2850	peptidyl-arginine hydroxylation
DGN11_15400	COG0567	Dehydrogenase, E1 component
DGN11_15425	COG1132	(ABC) transporter
DGN11_15430	COG0583	DNA-binding transcription factor activity
DGN11_15460	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
DGN11_15470	COG0484	heat shock protein binding
DGN11_15475	COG0443	Heat shock 70 kDa protein
DGN11_15480	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DGN11_15485	COG1420	regulation of RNA biosynthetic process
DGN11_15490	COG0497	DNA recombination
DGN11_15500	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DGN11_15515	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DGN11_15530	COG0582	viral genome integration into host DNA
DGN11_15535	COG3328	transposase activity
DGN11_15545	COG3706	GGDEF domain
DGN11_15590	COG0583	DNA-binding transcription factor activity
DGN11_15600	COG0415	Belongs to the DNA photolyase family
DGN11_15605	COG0305	Participates in initiation and elongation during chromosome replication
DGN11_15615	COG0367	asparagine synthase
DGN11_15635	COG1960	acyl-CoA dehydrogenase activity
DGN11_15650	COG0084	hydrolase, TatD family'
DGN11_15655	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DGN11_15710	COG0386	Belongs to the glutathione peroxidase family
DGN11_15720	COG0339	signal peptide processing
DGN11_15770	COG2814	Major facilitator Superfamily
DGN11_15775	COG1566	PFAM secretion protein HlyD family protein
DGN11_15800	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DGN11_15815	COG4774	siderophore transport
DGN11_15825	COG0367	asparagine synthase
DGN11_15830	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DGN11_15835	COG1393	Belongs to the ArsC family
DGN11_15845	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
DGN11_15885	COG0052	Belongs to the universal ribosomal protein uS2 family
DGN11_15890	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DGN11_15900	COG0528	UMP kinase activity
DGN11_15905	COG0233	cytoplasmic translational termination
DGN11_15910	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DGN11_15915	COG0575	Belongs to the CDS family
DGN11_15920	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DGN11_15925	COG0750	zinc metalloprotease
DGN11_15940	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DGN11_15945	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DGN11_15950	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DGN11_15955	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DGN11_15970	COG0825	malonyl-CoA metabolic process
DGN11_15985	COG1981	membrane
DGN11_16005	COG1695	Transcriptional regulator
DGN11_16030	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DGN11_16040	COG2040	homocysteine
DGN11_16045	COG0833	amino acid
DGN11_16050	COG0346	lactoylglutathione lyase activity
DGN11_16055	COG1131	(ABC) transporter
DGN11_16065	COG3039	Transposase
DGN11_16080	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DGN11_16080	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DGN11_16090	COG2878	Part of a membrane complex involved in electron transport
DGN11_16115	COG1595	DNA-templated transcription, initiation
DGN11_16140	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DGN11_16155	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DGN11_16160	COG0251	oxidation-reduction process
DGN11_16170	COG0392	lysyltransferase activity
DGN11_16170	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DGN11_16205	COG2814	Major facilitator Superfamily
DGN11_16210	COG1902	pentaerythritol trinitrate reductase activity
DGN11_16220	COG2824	Alkylphosphonate utilization operon protein PhnA
DGN11_16230	COG1047	Peptidyl-prolyl cis-trans
DGN11_16235	COG1077	Cell shape determining protein MreB Mrl
DGN11_16250	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DGN11_16260	COG5487	UPF0391 membrane protein
DGN11_16265	COG1451	nucleotide metabolic process
DGN11_16290	COG0183	Belongs to the thiolase family
DGN11_16320	COG1793	dna ligase
DGN11_16320	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DGN11_16330	COG1793	dna ligase
DGN11_16335	COG1201	RNA secondary structure unwinding
DGN11_16345	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DGN11_16350	COG1278	Cold shock
DGN11_16355	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DGN11_16360	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DGN11_16365	COG1472	Belongs to the glycosyl hydrolase 3 family
DGN11_16370	COG3046	protein related to deoxyribodipyrimidine photolyase
DGN11_16375	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
DGN11_16380	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DGN11_16385	COG2954	triphosphatase activity
DGN11_16390	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DGN11_16400	COG1381	Involved in DNA repair and RecF pathway recombination
DGN11_16405	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DGN11_16410	COG0571	ribonuclease III activity
DGN11_16425	COG0481	GTPase activity
DGN11_16430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DGN11_16445	COG1024	Enoyl-CoA hydratase
DGN11_16445	COG1250	3-hydroxyacyl-CoA dehydrogenase
DGN11_16455	COG3039	Transposase
DGN11_16480	COG1024	Enoyl-CoA hydratase
DGN11_16485	COG1960	acyl-CoA dehydrogenase activity
DGN11_16505	COG3867	Arabinogalactan endo-beta-1,4-galactanase
DGN11_16510	COG3250	beta-galactosidase activity
DGN11_16535	COG3328	transposase activity
DGN11_16545	COG3039	Transposase
DGN11_16560	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DGN11_16570	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
DGN11_16595	COG0534	Mate efflux family protein
DGN11_16600	COG0335	large ribosomal subunit rRNA binding
DGN11_16605	COG0336	Belongs to the RNA methyltransferase TrmD family
DGN11_16610	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DGN11_16615	COG0228	four-way junction DNA binding
DGN11_16630	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DGN11_16635	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DGN11_16660	COG4191	Histidine kinase
DGN11_16660	COG0784	Response regulator, receiver
DGN11_16665	COG3850	Histidine kinase
DGN11_16665	COG3437	response regulator, receiver
DGN11_16665	COG2205	protein histidine kinase activity
DGN11_16665	COG4999	Histidine kinase
DGN11_16670	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DGN11_16680	COG2205	protein histidine kinase activity
DGN11_16685	COG5507	3-demethylubiquinone-9 3-methyltransferase
DGN11_16695	COG4771	TonB-dependent receptor
DGN11_16720	COG2172	sigma factor antagonist activity
DGN11_16725	COG1366	Belongs to the anti-sigma-factor antagonist family
DGN11_16730	COG1366	Belongs to the anti-sigma-factor antagonist family
DGN11_16740	COG0326	Molecular chaperone. Has ATPase activity
DGN11_16745	COG2207	Transcriptional regulator
DGN11_16755	COG3152	Membrane
DGN11_16770	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DGN11_16775	COG1845	cytochrome c oxidase, subunit III
DGN11_16780	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DGN11_16805	COG3328	transposase activity
DGN11_16815	COG3328	transposase activity
DGN11_16870	COG2022	thiamine diphosphate biosynthetic process
DGN11_16875	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DGN11_16880	COG0471	metal ion transport
DGN11_16880	COG3273	potassium ion transport
DGN11_16905	COG1970	mechanosensitive ion channel activity
DGN11_16915	COG1609	Transcriptional regulator
DGN11_16925	COG3250	beta-galactosidase activity
DGN11_16930	COG4948	Mandelate Racemase Muconate Lactonizing
DGN11_16940	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DGN11_16950	COG0308	aminopeptidase N
DGN11_16955	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DGN11_16960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DGN11_16965	COG2895	sulfate adenylyltransferase (ATP) activity
DGN11_16965	COG0529	Catalyzes the synthesis of activated sulfate
DGN11_16970	COG0175	sulfate reduction
DGN11_16975	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DGN11_16980	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DGN11_16985	COG0175	sulfate reduction
DGN11_17005	COG3039	Transposase
DGN11_17025	COG2205	protein histidine kinase activity
DGN11_17025	COG2198	Histidine kinase
DGN11_17025	COG0784	Response regulator, receiver
DGN11_17045	COG1648	precorrin-2 dehydrogenase activity
DGN11_17045	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DGN11_17060	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
DGN11_17065	COG3588	fructose-bisphosphate aldolase
DGN11_17080	COG0469	pyruvate kinase activity
DGN11_17090	COG0126	phosphoglycerate kinase activity
DGN11_17115	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DGN11_17125	COG3047	cAMP biosynthetic process
DGN11_17130	COG3047	cAMP biosynthetic process
DGN11_17140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DGN11_17140	COG3453	Protein conserved in bacteria
DGN11_17145	COG0725	ABC transporter, periplasmic molybdate-binding protein
DGN11_17150	COG4149	molybdate abc transporter
DGN11_17155	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
DGN11_17190	COG1376	ErfK ybiS ycfS ynhG family protein
DGN11_17195	COG0739	heme binding
DGN11_17200	COG4773	Receptor
DGN11_17210	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DGN11_17215	COG1301	dicarboxylic acid transport
DGN11_17220	COG3039	Transposase
DGN11_17235	COG2304	oxidoreductase activity
DGN11_17255	COG0714	Associated with various cellular activities
DGN11_17295	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DGN11_17320	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DGN11_17330	COG2721	sulfolactate sulfo-lyase activity
DGN11_17345	COG2271	Major facilitator Superfamily
DGN11_17360	COG0583	DNA-binding transcription factor activity
DGN11_17365	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DGN11_17380	COG1561	YicC-like family, N-terminal region
DGN11_17385	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DGN11_17395	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DGN11_17400	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DGN11_17415	COG0006	proline dipeptidase activity
DGN11_17425	COG0006	proline dipeptidase activity
DGN11_17430	COG3079	Belongs to the UPF0149 family
DGN11_17450	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DGN11_17460	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DGN11_17470	COG2912	Transglutaminase-like superfamily
DGN11_17480	COG1773	rubredoxin
DGN11_17485	COG0352	thiamine-phosphate diphosphorylase activity
DGN11_17505	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DGN11_17520	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DGN11_17555	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DGN11_17560	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DGN11_17565	COG1028	Short-chain dehydrogenase reductase Sdr
DGN11_17575	COG0671	phosphoesterase, PA-phosphatase related
DGN11_17580	COG3781	membrane
DGN11_17590	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DGN11_17595	COG0563	adenylate kinase activity
DGN11_17610	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DGN11_17620	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DGN11_17645	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DGN11_17660	COG0840	transmembrane signaling receptor activity
DGN11_17665	COG0405	Gamma-glutamyltransferase
DGN11_17670	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DGN11_17690	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DGN11_17695	COG0473	3-isopropylmalate dehydrogenase activity
DGN11_17700	COG0066	3-isopropylmalate dehydratase activity
DGN11_17710	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DGN11_17730	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DGN11_17735	COG1538	Outer membrane efflux protein
DGN11_17740	COG1519	Transferase
DGN11_17745	COG1560	Kdo2-lipid A biosynthetic process
DGN11_17770	COG0280	phosphate acetyltransferase
DGN11_17770	COG0281	malic enzyme
DGN11_17775	COG1301	dicarboxylic acid transport
DGN11_17790	COG3039	Transposase
DGN11_17805	COG0583	DNA-binding transcription factor activity
DGN11_17810	COG0667	Aldo Keto reductase
DGN11_17825	COG2197	response regulator
DGN11_17835	COG0642	Histidine kinase
DGN11_17855	COG2851	Citrate transporter
DGN11_17860	COG1028	Short-chain dehydrogenase reductase Sdr
DGN11_17865	COG1609	Transcriptional regulator
DGN11_17870	COG2211	Major facilitator Superfamily
DGN11_17900	COG1162	GTPase activity
DGN11_17905	COG0436	Aminotransferase
DGN11_17920	COG0726	polysaccharide deacetylase
DGN11_17925	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DGN11_17940	COG3964	amidohydrolase
DGN11_17945	COG0402	S-adenosylhomocysteine deaminase activity
DGN11_17965	COG3039	Transposase
DGN11_17970	COG1307	EDD domain protein, DegV family
DGN11_17975	COG0242	peptide deformylase activity
DGN11_18000	COG0457	Tetratricopeptide repeat
DGN11_18005	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
DGN11_18010	COG1215	transferase activity, transferring glycosyl groups
DGN11_18015	COG1215	transferase activity, transferring glycosyl groups
DGN11_18030	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DGN11_18085	COG2188	Transcriptional regulator
DGN11_18095	COG1450	Type ii and iii secretion system protein
DGN11_18110	COG3166	PFAM Fimbrial assembly family protein
DGN11_18115	COG3156	type II secretion system protein K
DGN11_18120	COG4795	General secretion pathway protein
DGN11_18125	COG2165	general secretion pathway protein
DGN11_18130	COG4970	Tfp pilus assembly protein FimT
DGN11_18135	COG2165	general secretion pathway protein
DGN11_18140	COG1459	type II secretion system
DGN11_18150	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DGN11_18155	COG1404	Belongs to the peptidase S8 family
DGN11_18160	COG5295	Hep Hag repeat protein
DGN11_18165	COG1404	Belongs to the peptidase S8 family
DGN11_18170	COG5295	Hep Hag repeat protein
DGN11_18175	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DGN11_18175	COG0047	phosphoribosylformylglycinamidine synthase activity
DGN11_18185	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DGN11_18200	COG4974	Belongs to the 'phage' integrase family
DGN11_18215	COG0795	lipopolysaccharide-transporting ATPase activity
DGN11_18225	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DGN11_18240	COG0525	valine-tRNA ligase activity
DGN11_18275	COG1183	phosphatidylcholine synthase activity
DGN11_18285	COG0442	prolyl-tRNA aminoacylation
DGN11_18300	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DGN11_18305	COG1127	ABC transporter
DGN11_18310	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DGN11_18310	COG3218	ABC-type transport auxiliary lipoprotein component
DGN11_18340	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DGN11_18345	COG0662	Cupin 2, conserved barrel domain protein
DGN11_18345	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
DGN11_18375	COG2086	electron transfer activity
DGN11_18390	COG0463	Glycosyl transferase, family 2
DGN11_18425	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
DGN11_18430	COG0438	transferase activity, transferring glycosyl groups
DGN11_18450	COG0438	transferase activity, transferring glycosyl groups
DGN11_18460	COG0626	cystathionine gamma-synthase activity
DGN11_18490	COG0625	glutathione transferase activity
DGN11_18505	COG0513	Belongs to the DEAD box helicase family
DGN11_18515	COG4771	TonB-dependent receptor
DGN11_18525	COG0720	synthase
DGN11_18550	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DGN11_18555	COG1956	GAF domain-containing protein
DGN11_18565	COG2819	hydrolase of the alpha beta superfamily
DGN11_18575	COG0546	phosphoglycolate phosphatase activity
DGN11_18580	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DGN11_18585	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DGN11_18600	COG0339	signal peptide processing
DGN11_18650	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DGN11_18655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DGN11_18660	COG1136	(ABC) transporter
DGN11_18665	COG0577	efflux transmembrane transporter activity
DGN11_18670	COG0577	efflux transmembrane transporter activity
DGN11_18670	COG1136	(ABC) transporter
DGN11_18685	COG4191	Histidine kinase
DGN11_18690	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DGN11_18710	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DGN11_18715	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DGN11_18720	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DGN11_18725	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DGN11_18730	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DGN11_18735	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DGN11_18745	COG0356	it plays a direct role in the translocation of protons across the membrane
DGN11_18765	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DGN11_18775	COG0508	dehydrogenase complex catalyzes the overall conversion of
DGN11_18815	COG2011	ABC-type metal ion transport system permease component
DGN11_18820	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DGN11_18825	COG0697	spore germination
DGN11_18830	COG1666	GTP binding
DGN11_18840	COG5002	protein histidine kinase activity
DGN11_18840	COG0784	Response regulator, receiver
DGN11_18840	COG2198	Histidine kinase
DGN11_18875	COG1187	pseudouridine synthase activity
DGN11_18880	COG2813	Specifically methylates the guanine in position
DGN11_18900	COG2205	protein histidine kinase activity
DGN11_18900	COG2202	Pas domain
DGN11_18920	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DGN11_18925	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DGN11_18985	COG0842	Transport permease protein
DGN11_18990	COG1131	(ABC) transporter
DGN11_18995	COG0025	NhaP-type Na H and K H
DGN11_19005	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
DGN11_19010	COG1573	uracil-dna glycosylase
DGN11_19020	COG3384	dioxygenase
DGN11_19030	COG0583	DNA-binding transcription factor activity
DGN11_19040	COG0667	Aldo Keto reductase
DGN11_19055	COG3590	peptidase
DGN11_19070	COG0531	amino acid
DGN11_19085	COG2972	Histidine kinase
DGN11_19110	COG3685	Protein conserved in bacteria
DGN11_19115	COG3546	catalase activity
DGN11_19150	COG2204	response regulator
DGN11_19165	COG1271	oxidase subunit
DGN11_19170	COG1294	oxidase, subunit
DGN11_19185	COG1028	Short-chain dehydrogenase reductase Sdr
DGN11_19190	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DGN11_19210	COG1132	(ABC) transporter
DGN11_19225	COG1063	alcohol dehydrogenase
DGN11_19300	COG0251	oxidation-reduction process
DGN11_19320	COG3328	transposase activity
DGN11_19335	COG0583	DNA-binding transcription factor activity
DGN11_19340	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DGN11_19370	COG0659	secondary active sulfate transmembrane transporter activity
DGN11_19380	COG0024	Methionine aminopeptidase
DGN11_19420	COG3328	transposase activity
DGN11_19425	COG0582	viral genome integration into host DNA
DGN11_19440	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DGN11_19445	COG1490	D-aminoacyl-tRNA deacylase activity
DGN11_19450	COG1560	Kdo2-lipid A biosynthetic process
DGN11_19505	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DGN11_19505	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DGN11_19510	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DGN11_19515	COG0242	peptide deformylase activity
DGN11_19520	COG1652	LysM domain
DGN11_19525	COG0758	DNA mediated transformation
DGN11_19545	COG1754	DNA topoisomerase type I activity
DGN11_19545	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DGN11_19550	COG0009	L-threonylcarbamoyladenylate synthase
DGN11_19565	COG1028	Short-chain dehydrogenase reductase Sdr
DGN11_19580	COG0616	signal peptide processing
DGN11_19585	COG0534	Mate efflux family protein
DGN11_19605	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DGN11_19610	COG0625	glutathione transferase activity
DGN11_19625	COG1252	NADH dehydrogenase
DGN11_19635	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DGN11_19640	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DGN11_19645	COG3437	response regulator, receiver
DGN11_19650	COG2177	Part of the ABC transporter FtsEX involved in
DGN11_19655	COG2884	Cell division ATP-binding protein ftsE
DGN11_19660	COG0513	Belongs to the DEAD box helicase family
DGN11_19665	COG3118	belongs to the thioredoxin family
DGN11_19670	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DGN11_19675	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
DGN11_19680	COG0583	DNA-binding transcription factor activity
DGN11_19700	COG1652	LysM domain
DGN11_19705	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DGN11_19705	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DGN11_19710	COG1473	amidohydrolase
DGN11_19715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DGN11_19720	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DGN11_19740	COG5383	Protein conserved in bacteria
DGN11_19780	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
DGN11_19785	COG3023	N-Acetylmuramoyl-L-alanine amidase
DGN11_19795	COG4948	Mandelate Racemase Muconate Lactonizing
DGN11_19805	COG0531	amino acid
DGN11_19825	COG2133	pyrroloquinoline quinone binding
DGN11_19835	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DGN11_19840	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DGN11_19850	COG1610	YqeY-like protein
DGN11_19860	COG1295	ribonuclease BN
DGN11_19865	COG0358	DNA primase activity
DGN11_19880	COG0109	protoheme IX farnesyltransferase activity
DGN11_19910	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
DGN11_19925	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DGN11_19970	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DGN11_19975	COG0739	heme binding
DGN11_19980	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
DGN11_19990	COG2211	Major facilitator Superfamily
DGN11_19995	COG0708	Exodeoxyribonuclease III
DGN11_20000	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DGN11_20010	COG1192	Involved in chromosome partitioning
DGN11_20015	COG1475	DNA binding
DGN11_20035	COG0463	Glycosyl transferase, family 2
DGN11_20055	COG0756	dUTP diphosphatase activity
DGN11_20060	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DGN11_20065	COG2003	Belongs to the UPF0758 family
DGN11_20070	COG0018	arginyl-trna synthetase
DGN11_20085	COG4221	oxidoreductase activity
DGN11_20090	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DGN11_20090	COG2755	lipolytic protein G-D-S-L family
DGN11_20110	COG1166	arginine decarboxylase activity
DGN11_20115	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DGN11_20140	COG3291	Pkd domain containing protein
DGN11_20140	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DGN11_20160	COG0606	chelatase, subunit chli
DGN11_20175	COG4943	cyclic-guanylate-specific phosphodiesterase activity
DGN11_20210	COG1690	Belongs to the RtcB family
DGN11_20245	COG1090	epimerase
DGN11_20255	COG0642	Histidine kinase
DGN11_20280	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DGN11_20305	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DGN11_20310	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DGN11_20325	COG3328	transposase activity
DGN11_20330	COG0753	catalase activity
DGN11_20345	COG2197	response regulator
DGN11_20350	COG4585	Histidine kinase
DGN11_20355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DGN11_20360	COG1136	(ABC) transporter
DGN11_20385	COG0697	spore germination
DGN11_20405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DGN11_20410	COG0180	Tryptophanyl-tRNA synthetase
DGN11_20415	COG3237	CsbD-like
DGN11_20455	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DGN11_20475	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DGN11_20525	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DGN11_20555	COG1199	ATP-dependent helicase activity
DGN11_20570	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DGN11_20640	COG0625	glutathione transferase activity
DGN11_20675	COG4555	ABC transporter
DGN11_20685	COG1476	TRANSCRIPTIONal
DGN11_20705	COG1230	cation diffusion facilitator family transporter
DGN11_20715	COG4774	siderophore transport
DGN11_20730	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DGN11_20735	COG1131	(ABC) transporter
DGN11_20740	COG0842	Transport permease protein
DGN11_20745	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DGN11_20775	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DGN11_20785	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DGN11_20795	COG0045	succinate-CoA ligase (ADP-forming) activity
DGN11_20795	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DGN11_20795	COG1042	CoA-binding domain protein
DGN11_20800	COG2239	Acts as a magnesium transporter
DGN11_20820	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DGN11_20825	COG3387	PFAM Glycoside hydrolase 15-related
DGN11_20840	COG3100	YcgL domain-containing protein
DGN11_20845	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DGN11_20855	COG0463	Glycosyl transferase, family 2
DGN11_20865	COG1028	Short-chain dehydrogenase reductase Sdr
DGN11_20900	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DGN11_20915	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DGN11_20945	COG4946	Tricorn protease homolog
DGN11_20945	COG1506	peptidase
DGN11_20945	COG0823	Involved in the tonB-independent uptake of proteins
DGN11_20970	COG0408	coproporphyrinogen oxidase activity
DGN11_21010	COG0515	serine threonine protein kinase
DGN11_21075	COG1595	DNA-templated transcription, initiation
DGN11_21130	COG3039	Transposase
DGN11_21195	COG0210	DNA helicase
DGN11_21205	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DGN11_21210	COG0583	DNA-binding transcription factor activity
DGN11_21215	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DGN11_21255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DGN11_21275	COG0357	Ribosomal RNA small subunit methyltransferase G
DGN11_21280	COG3540	Alkaline phosphatase
DGN11_21290	COG2091	lysine biosynthetic process via aminoadipic acid
DGN11_21305	COG0708	Exodeoxyribonuclease III
DGN11_21310	COG1846	Transcriptional regulator
DGN11_21310	COG1940	carbohydrate kinase activity
DGN11_21320	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DGN11_21335	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DGN11_21340	COG3162	membrane
DGN11_21350	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DGN11_21400	COG1028	Short-chain dehydrogenase reductase Sdr
DGN11_21405	COG0179	Fumarylacetoacetate (FAA) hydrolase
DGN11_21410	COG4948	Mandelate Racemase Muconate Lactonizing
DGN11_21415	COG3254	rhamnose metabolic process
DGN11_21420	COG0738	Major facilitator superfamily
DGN11_21425	COG1414	Transcriptional regulator
DGN11_21430	COG1971	Probably functions as a manganese efflux pump
DGN11_21435	COG2205	protein histidine kinase activity
DGN11_21450	COG3459	Glycosyltransferase 36 associated
DGN11_21455	COG2211	Major facilitator Superfamily
DGN11_21460	COG3265	gluconokinase activity
DGN11_21470	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DGN11_21495	COG2911	Protein conserved in bacteria
DGN11_21500	COG0729	surface antigen
DGN11_21510	COG3039	Transposase
DGN11_21515	COG3039	Transposase
DGN11_21540	COG3039	Transposase
DGN11_21555	COG0752	glycyl-tRNA synthetase alpha subunit
DGN11_21560	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DGN11_21575	COG0519	Catalyzes the synthesis of GMP from XMP
DGN11_21575	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DGN11_21585	COG0805	protein transport
DGN11_21590	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DGN11_21595	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DGN11_21605	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DGN11_21625	COG2974	May be involved in recombination
DGN11_21630	COG0037	tRNA processing
DGN11_21640	COG2115	Belongs to the xylose isomerase family
DGN11_21650	COG3661	Belongs to the glycosyl hydrolase 67 family
DGN11_21660	COG4948	Mandelate Racemase Muconate Lactonizing
DGN11_21670	COG1472	Belongs to the glycosyl hydrolase 3 family
DGN11_21675	COG0246	Mannitol dehydrogenase
DGN11_21755	COG3386	PFAM SMP-30 Gluconolaconase
DGN11_21765	COG3250	beta-galactosidase activity
DGN11_21770	COG1904	glucuronate isomerase
DGN11_21785	COG3693	PFAM glycoside hydrolase, family 10
DGN11_21800	COG2211	Major facilitator Superfamily
DGN11_21835	COG1028	Short-chain dehydrogenase reductase Sdr
DGN11_21835	COG3321	synthase
DGN11_21835	COG0604	alcohol dehydrogenase
DGN11_21840	COG2937	Belongs to the GPAT DAPAT family
DGN11_21875	COG0284	orotidine-5'-phosphate decarboxylase activity
DGN11_21880	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
DGN11_21885	COG3132	Protein of unknown function, DUF480
DGN11_21900	COG0210	DNA helicase
DGN11_21905	COG1435	thymidine kinase activity
DGN11_21915	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
DGN11_21925	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DGN11_21955	COG3135	benzoate transporter
DGN11_21980	COG0676	glucose-6-phosphate 1-epimerase activity
DGN11_21990	COG3012	SEC-C Motif Domain Protein
DGN11_21995	COG0730	response to heat
DGN11_22015	COG0302	gtp cyclohydrolase
DGN11_22040	COG1289	transmembrane transporter activity
DGN11_22045	COG0477	Major facilitator Superfamily
DGN11_22055	COG0583	DNA-binding transcription factor activity
DGN11_22060	COG4221	oxidoreductase activity
DGN11_22070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DGN11_22095	COG3328	transposase activity
DGN11_22110	COG3328	transposase activity
DGN11_22135	COG0564	pseudouridine synthase activity
DGN11_22150	COG3039	Transposase
DGN11_22160	COG3039	Transposase
DGN11_22165	COG3039	Transposase
DGN11_22180	COG1028	Short-chain dehydrogenase reductase Sdr
DGN11_22225	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DGN11_22230	COG1074	ATP-dependent DNA helicase activity
DGN11_22235	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
DGN11_22270	COG1127	ABC transporter
DGN11_22275	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DGN11_22280	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DGN11_22295	COG2853	Lipoprotein
DGN11_22305	COG0386	Belongs to the glutathione peroxidase family
DGN11_22335	COG0625	glutathione transferase activity
DGN11_22380	COG3077	Addiction module antitoxin, RelB DinJ family
DGN11_22385	COG3041	Addiction module toxin RelE StbE family
DGN11_22445	COG0840	transmembrane signaling receptor activity
DGN11_22470	COG3328	transposase activity
DGN11_22485	COG3537	Alpha-1,2-mannosidase
DGN11_22510	COG1929	Belongs to the glycerate kinase type-1 family
DGN11_22515	COG2271	Major facilitator Superfamily
DGN11_22530	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DGN11_22540	COG0861	Integral membrane protein TerC family
DGN11_22550	COG0584	glycerophosphoryl diester phosphodiesterase
DGN11_22565	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DGN11_22575	COG0706	membrane insertase activity
DGN11_22580	COG0594	ribonuclease P activity
DGN11_22690	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DGN11_22695	COG4691	Plasmid stability protein
DGN11_22700	COG1487	ribonuclease activity
DGN11_22935	COG3328	transposase activity
DGN11_23055	COG3328	transposase activity
DGN11_23060	COG3328	transposase activity
DGN11_23075	COG2951	lytic endotransglycosylase activity