locus-tag	class	description
C2859_00010	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
C2859_00015	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
C2859_00020	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
C2859_00025	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C2859_00035	ENOG4108K0D	peptidase, M48
C2859_00065	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
C2859_00075	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
C2859_00120	ENOG4105CN1	protease
C2859_00125	ENOG41063SB	peptidase
C2859_00135	ENOG4107VAM	peptidase, m28
C2859_00170	ENOG4105DQ4	alcohol dehydrogenase
C2859_00175	ENOG4105BZ8	glutamate synthase
C2859_00180	ENOG4105CBC	glutamate synthase
C2859_00210	ENOG4105EXG	Transcriptional regulator
C2859_00230	ENOG4105D3Q	Sugar transferase
C2859_00235	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
C2859_00245	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
C2859_00250	ENOG4107RA4	Glycosyl transferase (Group 1
C2859_00270	ENOG4105CAQ	asparagine synthetase
C2859_00285	ENOG4105CMR	udp-glucose 4-epimerase
C2859_00300	ENOG4105BZ1	(ABC) transporter
C2859_00330	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
C2859_00425	ENOG4108I5C	dEAD DEAH box helicase
C2859_00430	ENOG4108UT2	hemolysin iii
C2859_00455	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
C2859_00480	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
C2859_00490	ENOG41067RQ	csbd family
C2859_00510	ENOG4105D4Y	metalloprotease
C2859_00535	ENOG4105K63	Thioredoxin
C2859_00545	ENOG4105CSH	Transporter
C2859_00585	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
C2859_00615	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
C2859_00620	ENOG4105CGF	Aromatic amino acid aminotransferase
C2859_00625	ENOG4105CHB	tonB-dependent Receptor
C2859_00635	ENOG41082W1	Cupin 2, conserved barrel domain protein
C2859_00640	ENOG4105C26	Dehydrogenase
C2859_00665	ENOG4105DMF	Dehydrogenase
C2859_00680	ENOG4105BZU	Histidine kinase
C2859_00685	ENOG4108S01	response regulator
C2859_00705	ENOG4108M3R	transcriptional activator CadC
C2859_00710	ENOG4105RKW	reductase (By
C2859_00750	ENOG4108UK2	deaminase
C2859_00785	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
C2859_00790	ENOG4105CG3	alpha amylase, catalytic region
C2859_00795	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
C2859_00810	ENOG4105EBR	Carboxylesterase
C2859_00825	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
C2859_00835	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
C2859_00840	ENOG4105DSG	hydrolase family 43
C2859_00845	ENOG4105ETE	Transcriptional regulator (LacI family
C2859_00865	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
C2859_00870	ENOG4105CHR	reductase
C2859_00880	ENOG4107TDE	lipolytic protein G-D-S-L family
C2859_00895	ENOG4105MIR	Phenylalanine 4-monooxygenase
C2859_00900	ENOG4108YXU	transcriptional regulator AsnC family
C2859_00905	ENOG4105CNM	Receptor
C2859_00910	ENOG4105D78	K07001 NTE family protein
C2859_00920	ENOG4105DKW	ABC transporter
C2859_00935	ENOG4108IJ8	ABC transporter
C2859_00940	ENOG4105E90	ABC transporter
C2859_00970	ENOG4105CAF	HipA N-terminal domain protein
C2859_01000	ENOG4105D1F	ATP-binding protein
C2859_01005	ENOG4105M4E	phosphohistidine phosphatase, SixA
C2859_01015	ENOG4107RZC	phospholipase d
C2859_01025	ENOG4105KA0	thioesterase Superfamily protein
C2859_01065	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
C2859_01075	ENOG4105C5F	glutamine synthetase
C2859_01085	ENOG4105BZU	Histidine kinase
C2859_01090	ENOG4105CUX	Signal transduction histidine kinase
C2859_01095	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C2859_01100	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
C2859_01105	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
C2859_01115	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
C2859_01125	ENOG4105CHU	acetyl-coa acetyltransferase
C2859_01160	ENOG4107YZP	Rhodanese domain protein
C2859_01165	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
C2859_01170	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
C2859_01225	ENOG4105D00	flagellar biosynthetic protein flhB
C2859_01230	ENOG4105D7B	Flagellar biosynthesis protein flha
C2859_01235	ENOG4108JQA	flagellar
C2859_01240	ENOG4105CGA	flagellar basal-body rod protein FlgG
C2859_01250	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
C2859_01255	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
C2859_01270	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
C2859_01275	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
C2859_01305	ENOG410822I	Flagellar hook capping protein
C2859_01310	ENOG4105BZE	flagellar hook protein, FlgE
C2859_01320	ENOG4105DD5	Flagellar motor switch protein
C2859_01330	ENOG4105CN7	Flagellar biosynthetic protein FliP
C2859_01335	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C2859_01340	ENOG4105C7K	acetolactate synthase
C2859_01345	ENOG4108TQ9	Histidine kinase
C2859_01350	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C2859_01370	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
C2859_01385	ENOG4105E2T	synthase III
C2859_01390	ENOG4107R3N	Filamentation induced by cAMP protein fic
C2859_01395	ENOG4108J2P	Alpha beta hydrolase fold
C2859_01400	ENOG4105PI0	Ferredoxin
C2859_01405	ENOG410680H	amp-dependent synthetase and ligase
C2859_01410	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
C2859_01430	ENOG4105CPF	Cell wall formation (By similarity)
C2859_01440	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
C2859_01450	ENOG4105DR9	pseudouridine synthase
C2859_01460	ENOG4108YZN	class I peptide chain release factor
C2859_01470	ENOG4105D44	asparaginase
C2859_01475	ENOG4105DGW	oligopeptidase A
C2859_01515	ENOG4107R11	Transcriptional regulator
C2859_01520	ENOG4107QP3	malate synthase g
C2859_01530	ENOG4105BZU	Histidine kinase
C2859_01560	ENOG4107QX3	carboxylase
C2859_01565	ENOG4105C1G	acyl-Coa dehydrogenase
C2859_01620	ENOG4105CKI	cobalamin synthesis protein
C2859_01635	ENOG4108TZV	Membrane
C2859_01645	ENOG4105D6Z	AFG1 family ATPase
C2859_01650	ENOG4105K56	Transcriptional regulator
C2859_01655	ENOG4108ZHJ	Organic hydroperoxide resistance protein
C2859_01685	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
C2859_01700	ENOG4108R99	pseudouridine synthase
C2859_01705	ENOG4108KPZ	tonB-dependent Receptor
C2859_01715	ENOG4105CQ7	ATP-dependent helicase
C2859_01725	ENOG4108W15	Protein of unknown function (DUF1456)
C2859_01730	ENOG4105VT2	5-hydroxyisourate hydrolase
C2859_01735	ENOG4105E1J	oxidoreductase
C2859_01755	ENOG4105C5R	Aminotransferase
C2859_01765	ENOG4105EQ2	LysR family Transcriptional regulator
C2859_01770	ENOG4107RTG	Major Facilitator superfamily
C2859_01780	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
C2859_01790	ENOG4105DU0	nucleoside hydrolase
C2859_01800	ENOG4105C7N	Xanthine uracil vitamin C permease
C2859_01820	ENOG4105ETT	transcriptional Regulator, LysR family
C2859_01825	ENOG4105F8V	Hydrolase, tatD family
C2859_01840	ENOG4106NZI	LysR family Transcriptional regulator
C2859_01845	ENOG4105D94	Major Facilitator Superfamily
C2859_01860	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
C2859_01865	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
C2859_01885	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
C2859_01890	ENOG4105EB3	Histidine kinase
C2859_01895	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
C2859_01900	ENOG4105BZS	acriflavin resistance protein
C2859_01905	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
C2859_01920	ENOG4105WPN	DNA integration recombination invertion protein
C2859_01925	ENOG4105DZ2	Transcriptional regulator
C2859_01930	ENOG4108UZX	fmn reductase
C2859_01945	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
C2859_01960	ENOG4105ECR	NmrA family
C2859_02045	ENOG4105C01	Dihydroxy-acid dehydratase
C2859_02060	ENOG4108Z0R	Transferase
C2859_02070	ENOG4105D2S	major facilitator superfamily
C2859_02075	ENOG4105CPI	Metal Dependent Phosphohydrolase
C2859_02110	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
C2859_02120	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
C2859_02125	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
C2859_02130	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
C2859_02135	ENOG4105E98	transcriptional regulator DeoR family
C2859_02160	ENOG4105CHU	acetyl-coa acetyltransferase
C2859_02170	ENOG4105EU7	Protocatechuate 3,4-dioxygenase, beta
C2859_02175	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
C2859_02180	ENOG4105F2Z	3-oxoadipate enol-lactonase
C2859_02185	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
C2859_02200	ENOG4107HP6	Transcriptional regulator
C2859_02215	ENOG4105MH3	Protein of unknown function (DUF2490)
C2859_02220	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
C2859_02255	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
C2859_02260	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
C2859_02270	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
C2859_02275	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
C2859_02280	ENOG41081UC	Inherit from COG: Competence protein
C2859_02285	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
C2859_02350	ENOG4105VS8	Flagellar biosynthetic protein fliq
C2859_02370	ENOG4108HR8	type iii secretion
C2859_02390	ENOG4107Y59	type iii secretion
C2859_02405	ENOG4108JIR	Flagellum-specific ATP synthase
C2859_02415	ENOG4108TN6	type iii secretion
C2859_02420	ENOG4105K44	type iii secretion
C2859_02430	ENOG4105FTC	Lytic transglycosylase catalytic
C2859_02470	ENOG4105CKW	Inner membrane protein yedI
C2859_02475	ENOG4105BZU	Histidine kinase
C2859_02480	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
C2859_02485	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
C2859_02490	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
C2859_02515	ENOG4105K4T	epimerase
C2859_02520	ENOG4107ZQV	short-chain dehydrogenase reductase
C2859_02545	ENOG4105C1J	atp-dependent rna helicase
C2859_02550	ENOG4105C7S	Dehydrogenase
C2859_02560	ENOG4105CPP	Dehydrogenase, E1 component
C2859_02565	ENOG4107RUY	(E1 component), alpha subunit
C2859_02575	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
C2859_02580	ENOG4105DUX	Transporter
C2859_02595	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
C2859_02600	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
C2859_02605	ENOG4105F1J	Homogentisate 1,2-dioxygenase
C2859_02625	ENOG4105KJM	monovalent cation h antiporter subunit g
C2859_02630	ENOG4105W4C	monovalent cation H antiporter subunit F
C2859_02640	ENOG4107R4Z	monovalent cation h antiporter subunit d
C2859_02645	ENOG4108ZE9	Monovalent cation H antiporter subunit C
C2859_02650	ENOG4105D65	subunit l
C2859_02675	ENOG4105NVB	glycoside hydrolase, family 19
C2859_02700	ENOG4105C8V	SAICAR synthetase
C2859_02705	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
C2859_02720	ENOG4105KD7	acetyltransferase
C2859_02725	ENOG4107TE5	Lipid kinase
C2859_02730	ENOG4105CRQ	synthase (Component I)
C2859_02740	ENOG4105DDQ	anthranilate synthase
C2859_02755	ENOG4108I0Q	anthranilate phosphoribosyltransferase
C2859_02760	ENOG4105DK0	Indole-3-glycerol phosphate synthase
C2859_02770	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
C2859_02775	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
C2859_02785	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
C2859_02790	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
C2859_02795	ENOG4108UJD	30S ribosomal protein S9
C2859_02810	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
C2859_02820	ENOG4108UQY	Iron-storage protein
C2859_02825	ENOG4105BZU	Histidine kinase
C2859_02850	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
C2859_02870	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
C2859_02885	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
C2859_02900	ENOG4105EM2	membrane
C2859_02910	ENOG4105C12	Phosphoribosylglycinamide synthetase
C2859_02920	ENOG4105DC1	bifunctional purine biosynthesis protein purh
C2859_02925	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
C2859_02930	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
C2859_02935	ENOG41077RS	Phosphatase
C2859_02960	ENOG4108HPI	phosphatidate Cytidylyltransferase
C2859_02965	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
C2859_02990	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
C2859_03015	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
C2859_03025	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
C2859_03030	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
C2859_03035	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
C2859_03040	ENOG4105VF7	tolerance protein
C2859_03055	ENOG4105VV6	START domain-containing protein
C2859_03070	ENOG4105E1F	short-chain dehydrogenase reductase
C2859_03075	ENOG4108K8S	endonuclease I
C2859_03085	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
C2859_03090	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
C2859_03105	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
C2859_03130	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
C2859_03135	ENOG4105EX9	Membrane
C2859_03155	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
C2859_03160	ENOG4108YYC	ycei family
C2859_03190	ENOG4105WSE	Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity)
C2859_03205	ENOG41065ZS	Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme- A to the apo- acyl-carrier-protein of the malonate decarboxylase to yield holo- acyl-carrier-protein (By similarity)
C2859_03210	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
C2859_03225	ENOG4105DRR	Transcriptional regulator, GntR family
C2859_03265	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
C2859_03355	ENOG4107GJV	short-chain dehydrogenase reductase
C2859_03370	ENOG4105PDP	Short chain dehydrogenase
C2859_03380	ENOG4105CHF	Glutathione S-transferase
C2859_03400	ENOG4105EYF	MMPL domain protein
C2859_03410	ENOG4105C5Z	peptidase
C2859_03420	ENOG4107QS8	(LipO)protein
C2859_03430	ENOG4105BZU	Histidine kinase
C2859_03455	ENOG4105DFI	Membrane
C2859_03460	ENOG4105F87	Dehydratase
C2859_03480	ENOG4105D7N	magnesium and cobalt transport protein CorA
C2859_03490	ENOG4105E53	ec 3.2.1.28
C2859_03540	ENOG4105C8Q	Methyl-accepting chemotaxis
C2859_03545	ENOG4106R7G	Glycoside hydrolase family 5
C2859_03550	ENOG4105CHH	sulfate transporter
C2859_03560	ENOG4105BZU	Histidine kinase
C2859_03580	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
C2859_03590	ENOG4108HRK	Histidine kinase
C2859_03595	ENOG4108NEV	two component transcriptional regulator, LytTR family
C2859_03600	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
C2859_03650	ENOG4105WD1	Membrane
C2859_03660	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
C2859_03670	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
C2859_03675	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
C2859_03680	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
C2859_03705	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
C2859_03710	ENOG4105BZU	Histidine kinase
C2859_03715	ENOG4105CD8	aminopeptidase N
C2859_03735	ENOG4105DZG	Dehydrogenase
C2859_03740	ENOG4108Q1J	Extracellular solute-binding protein, family 3
C2859_03765	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
C2859_03775	ENOG4105DFF	Rod shape-determining protein mreb
C2859_03780	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
C2859_03795	ENOG4105CNI	cell division protein FtsW
C2859_03805	ENOG4105CVE	Lytic murein transglycosylase
C2859_03810	ENOG4105K6T	rare lipoprotein A
C2859_03820	ENOG4105DZ1	carboxypeptidase
C2859_03835	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
C2859_03840	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
C2859_03845	ENOG4105CN1	protease
C2859_03855	ENOG4105EGI	Transcriptional regulator
C2859_03900	ENOG4108J5G	6-phosphogluconate dehydrogenase
C2859_03905	ENOG4105D9R	oxidoreductase
C2859_03910	ENOG4105W4M	Transport-associated protein
C2859_03915	ENOG4105BZU	Histidine kinase
C2859_03925	ENOG4105BZU	Histidine kinase
C2859_03935	ENOG4105CHR	reductase
C2859_03980	ENOG4105GVR	general secretion pathway protein D
C2859_03985	ENOG4107QHF	type ii secretion system protein e
C2859_03990	ENOG4105D7Q	type ii secretion system
C2859_03995	ENOG4108VAU	general secretion pathway protein G
C2859_04005	ENOG4105X5Z	General secretion pathway protein I
C2859_04015	ENOG4108RTD	type II secretion system protein K
C2859_04040	ENOG4105CNT	hydrolase family 2
C2859_04055	ENOG4105FDP	GntR family transcriptional regulator
C2859_04065	ENOG4105ETE	Transcriptional regulator (LacI family
C2859_04070	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
C2859_04075	ENOG4105CE4	GlcNAc 6-P deacetylase
C2859_04085	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
C2859_04090	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
C2859_04095	ENOG4105C26	Dehydrogenase
C2859_04100	ENOG4105C94	Transporter
C2859_04115	ENOG4108Z33	Thiol disulfide Interchange Protein
C2859_04125	ENOG4106RE7	Cytochrome
C2859_04130	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
C2859_04135	ENOG4105CY0	Metallo-Beta-Lactamase
C2859_04155	ENOG4105JJR	Histidine kinase
C2859_04160	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
C2859_04185	ENOG4108QBQ	Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione (By similarity)
C2859_04200	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
C2859_04205	ENOG4105JAB	phenazine biosynthesis protein, phzf family
C2859_04220	ENOG4105C5H	ABC transporter
C2859_04230	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
C2859_04235	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
C2859_04245	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
C2859_04260	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
C2859_04265	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
C2859_04270	ENOG4107YIM	Involved in the transcription termination process (By similarity)
C2859_04275	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
C2859_04300	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
C2859_04305	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
C2859_04310	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
C2859_04315	ENOG4105C08	Histidine kinase
C2859_04320	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
C2859_04335	ENOG4105CQB	FAD linked oxidase domain protein
C2859_04340	ENOG4105S2T	inner membrane protein YbcI
C2859_04345	ENOG41082RQ	UPF0102 protein
C2859_04380	ENOG4108V6E	Cell division protein mraZ
C2859_04385	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
C2859_04390	ENOG4106932	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
C2859_04395	ENOG4105CJN	penicillin-binding protein
C2859_04400	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
C2859_04405	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
C2859_04410	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
C2859_04420	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
C2859_04425	ENOG4105DFU	Cell wall formation (By similarity)
C2859_04430	ENOG4105CPF	Cell wall formation (By similarity)
C2859_04435	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
C2859_04440	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
C2859_04445	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
C2859_04450	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
C2859_04460	ENOG4105DR5	peptidase
C2859_04465	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
C2859_04470	ENOG4105M6F	mutator MutT protein
C2859_04480	ENOG4105SYT	Methylenetetrahydrofolate reductase
C2859_04555	ENOG4105DXX	methyltransferase
C2859_04560	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
C2859_04570	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
C2859_04605	ENOG4105D6F	Phosphatase
C2859_04615	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
C2859_04625	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
C2859_04630	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
C2859_04640	ENOG4108RVA	ribokinase
C2859_04645	ENOG4105D9N	nucleoside
C2859_04655	ENOG4105CPC	Aldo Keto reductase
C2859_04665	ENOG4105D05	Receptor
C2859_04685	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
C2859_04700	ENOG4105E2B	Taurine dioxygenase
C2859_04710	ENOG4108I0Y	(ABC) transporter
C2859_04715	ENOG4108UJV	acyl-CoA thioesterase i
C2859_04720	ENOG4105ETX	regulatoR
C2859_04725	ENOG4105DHQ	Histidine kinase
C2859_04740	ENOG41080IJ	Diacylglycerol kinase
C2859_04760	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
C2859_04765	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
C2859_04780	ENOG4107SM7	Transcriptional regulator
C2859_04785	ENOG4107T8P	acyl-Coa dehydrogenase
C2859_04790	ENOG4105D7T	ABC transporter
C2859_04795	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
C2859_04805	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
C2859_04810	ENOG4108UZX	fmn reductase
C2859_04840	ENOG4105DEF	Extracellular solute-binding protein, family 5
C2859_04850	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
C2859_04860	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
C2859_04865	ENOG4105NWN	ApaG protein
C2859_04870	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
C2859_04875	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
C2859_04880	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
C2859_04885	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
C2859_04895	ENOG4108WBT	adenosyltransferase
C2859_04910	ENOG4105D0A	hydroxylase
C2859_04915	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
C2859_04950	ENOG4105DDW	LysR family Transcriptional regulator
C2859_04965	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
C2859_05000	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
C2859_05020	ENOG4105DXC	membrane
C2859_05030	ENOG4105CX6	glutaminyL-tRNA synthetase
C2859_05045	ENOG4105BZU	Histidine kinase
C2859_05050	ENOG4105BZU	Histidine kinase
C2859_05055	ENOG4105WH1	Two component transcriptional regulator luxr family
C2859_05065	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
C2859_05075	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
C2859_05080	ENOG4105NXH	GreA GreB family elongation factor
C2859_05090	ENOG4105C5Q	Transcriptional regulator
C2859_05105	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
C2859_05125	ENOG4105C2M	dna polymerase I
C2859_05155	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
C2859_05175	ENOG4105W8H	transhydrogenase (subunit alpha
C2859_05180	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
C2859_05195	ENOG4105CM2	brancheD-chain amino acid aminotransferase
C2859_05200	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
C2859_05205	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
C2859_05210	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
C2859_05215	ENOG4108Z66	YbaK ebsC protein
C2859_05235	ENOG4105CS1	NAD(P)H quinone oxidoreductase
C2859_05240	ENOG4107S2Z	UPF0761 membrane protein
C2859_05245	ENOG4107QX9	Thiol disulfide interChange protein
C2859_05260	ENOG4105CSR	polyphosphate kinase 2
C2859_05265	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
C2859_05275	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
C2859_05280	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
C2859_05285	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
C2859_05290	ENOG4105QVB	outer membrane lipoprotein LolB
C2859_05295	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
C2859_05305	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
C2859_05310	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
C2859_05315	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
C2859_05320	ENOG4105C3G	gtp-binding protein
C2859_05340	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
C2859_05350	ENOG4105PM1	preprotein translocase subunit SecE
C2859_05355	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
C2859_05360	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
C2859_05365	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
C2859_05370	ENOG4108VZM	50s ribosomal protein L10
C2859_05375	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
C2859_05380	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C2859_05385	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C2859_05390	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
C2859_05395	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
C2859_05400	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
C2859_05405	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
C2859_05410	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
C2859_05415	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
C2859_05420	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
C2859_05425	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
C2859_05430	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C2859_05435	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
C2859_05440	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
C2859_05445	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
C2859_05450	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
C2859_05460	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
C2859_05465	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
C2859_05470	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
C2859_05475	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C2859_05480	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
C2859_05485	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
C2859_05490	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
C2859_05495	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
C2859_05500	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
C2859_05510	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
C2859_05515	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
C2859_05520	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C2859_05525	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
C2859_05530	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
C2859_05535	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C2859_05540	ENOG4108ZT0	50S ribosomal protein l17
C2859_05545	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
C2859_05565	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
C2859_05575	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
C2859_05590	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
C2859_05595	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
C2859_05600	ENOG4108K3A	Glutathione S-transferase
C2859_05620	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
C2859_05625	ENOG4105CIS	alcohol dehydrogenase
C2859_05635	ENOG4105CDV	Ompa motb domain protein
C2859_05645	ENOG4108R99	pseudouridine synthase
C2859_05655	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
C2859_05660	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
C2859_05665	ENOG4108I5D	sulfate abc transporter
C2859_05675	ENOG4108IJ6	ABC transporter
C2859_05685	ENOG4105CPQ	Dehydrogenase
C2859_05700	ENOG4105HSS	phospholipase C
C2859_05710	ENOG4105CVJ	phosphoglycerate mutase
C2859_05715	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
C2859_05730	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
C2859_05735	ENOG4105ED9	Protein of unknown function (DUF455)
C2859_05755	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
C2859_05760	ENOG4105EYK	Phosphatidylglycerophosphatase B
C2859_05765	ENOG4105BZF	Glycosyl transferase (Group 1
C2859_05770	ENOG4105C9X	ppx gppa phosphatase
C2859_05775	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
C2859_05780	ENOG4105BZU	Histidine kinase
C2859_05785	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C2859_05790	ENOG4105ERG	peptidase m48, ste24p
C2859_05795	ENOG4105VW4	glutaredoxin 3
C2859_05805	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
C2859_06060	ENOG4105ED4	portal protein
C2859_06120	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
C2859_06125	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
C2859_06130	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
C2859_06160	ENOG4105EIN	peptidylprolyl cis-trans isomerase
C2859_06170	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
C2859_06180	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
C2859_06185	ENOG4107RZZ	dna polymerase iii epsilon subunit
C2859_06190	ENOG4108ZF3	Phosphatase
C2859_06205	ENOG4105DKP	glycosyl transferase, family 9
C2859_06210	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
C2859_06215	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
C2859_06220	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
C2859_06235	ENOG4105M00	molybdopterin converting factor, subunit 1
C2859_06240	ENOG4108ZAF	Molybdopterin
C2859_06255	ENOG4107QMP	dna polymerase iii subunits gamma and tau
C2859_06260	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
C2859_06265	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
C2859_06270	ENOG4105K59	histidine triad (HIT) protein
C2859_06280	ENOG4105F8C	transglutaminase domain-containing protein
C2859_06290	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
C2859_06300	ENOG41089I4	Inherit from COG: Glycosyl transferase, family 2
C2859_06310	ENOG4108UHJ	MAF-like protein
C2859_06315	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
C2859_06320	ENOG4105VGS	50s ribosomal protein l32
C2859_06325	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
C2859_06335	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
C2859_06340	ENOG4105CHR	reductase
C2859_06345	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
C2859_06350	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
C2859_06360	ENOG4105HHA	aminodeoxychorismate lyase
C2859_06365	ENOG4107QRG	dna polymerase iii
C2859_06405	ENOG4108JU7	Transcriptional regulator
C2859_06410	ENOG4105CR4	methylisocitrate lyase
C2859_06415	ENOG4105BZN	citrate synthase
C2859_06420	ENOG4108I0Z	Aconitate hydratase
C2859_06425	ENOG4105YAJ	CopG Arc MetJ
C2859_06440	ENOG4105C7F	AcnD-accessory protein PrpF
C2859_06460	ENOG4105DN3	alpha-2-macroglobulin domain protein
C2859_06480	ENOG4108JQB	penicillin-binding protein 1C
C2859_06505	ENOG4105M3Z	response regulator
C2859_06510	ENOG4107QJR	hflk protein
C2859_06515	ENOG4105EPW	hflc protein
C2859_06525	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
C2859_06530	ENOG4105CD8	aminopeptidase N
C2859_06535	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
C2859_06540	ENOG4108XFH	Transcriptional regulator
C2859_06550	ENOG4108F3G	Type I restriction-modification system, R subunit
C2859_06570	ENOG4107QTH	restriction modification system DNA specificity domain
C2859_06600	ENOG4105CVJ	phosphoglycerate mutase
C2859_06605	ENOG4107Z4K	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
C2859_06615	ENOG4105BZP	glycoside hydrolase 15-related
C2859_06620	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
C2859_06625	ENOG4105CWX	Alpha-1,2-mannosidase
C2859_06630	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
C2859_06645	ENOG4105C3M	thioredoxin reductase
C2859_06670	ENOG4105C7W	Xanthine dehydrogenase
C2859_06675	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
C2859_06680	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
C2859_06715	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
C2859_06730	ENOG4105C0B	DNA polymerase III (alpha subunit)
C2859_06750	ENOG4105EPD	Oligopeptide transporter, Opt family
C2859_06765	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
C2859_06785	ENOG4106AXJ	AraC family transcriptional regulator
C2859_06810	ENOG4105CV8	reductase
C2859_06815	ENOG4105EBR	Carboxylesterase
C2859_06820	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C2859_06825	ENOG4105C2C	drug resistance transporter, Bcr CflA
C2859_06840	ENOG4105DIJ	Phosphoethanolamine transferase
C2859_06855	ENOG4105ETX	regulatoR
C2859_06860	ENOG4105DHQ	Histidine kinase
C2859_06870	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
C2859_06875	ENOG4107QMS	site-determining protein
C2859_06880	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
C2859_06895	ENOG4105BZU	Histidine kinase
C2859_06900	ENOG4105WH1	Two component transcriptional regulator luxr family
C2859_06950	ENOG4107SPG	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
C2859_06960	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
C2859_06980	ENOG4105C29	acyl-CoA thioesterase
C2859_06995	ENOG4108TGP	Thioesterase superfamily protein
C2859_07000	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
C2859_07005	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
C2859_07010	ENOG4105K46	50S ribosomal protein l27
C2859_07015	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C2859_07020	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
C2859_07025	ENOG4105CJR	Integral membrane protein (MviN
C2859_07030	ENOG4105DTN	riboflavin biosynthesis protein ribF
C2859_07035	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
C2859_07040	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
C2859_07045	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
C2859_07055	ENOG4105E2S	oxidase) subunit II
C2859_07060	ENOG4105BZ9	Cytochrome C oxidase, subunit I
C2859_07065	ENOG4105CCU	oxidase (Subunit III)
C2859_07070	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
C2859_07085	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
C2859_07090	ENOG4105KAF	membrAne
C2859_07105	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
C2859_07120	ENOG4107MMM	Anti-sigma-factor antagonist
C2859_07125	ENOG4105FUA	antagonist
C2859_07130	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
C2859_07140	ENOG4105BZU	Histidine kinase
C2859_07165	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
C2859_07170	ENOG4105C08	Histidine kinase
C2859_07175	ENOG4107Z5C	methylesterase
C2859_07180	ENOG4105BZU	Histidine kinase
C2859_07185	ENOG4105BZU	Histidine kinase
C2859_07190	ENOG4105CQZ	Histidine kinase
C2859_07205	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
C2859_07210	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
C2859_07215	ENOG4105CRE	cytochrome C
C2859_07220	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C2859_07225	ENOG4107QWG	2-Nitropropane dioxygenase
C2859_07235	ENOG4105K5M	30s ribosomal protein S16
C2859_07240	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
C2859_07245	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
C2859_07250	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
C2859_07255	ENOG4107QJQ	Mate efflux family protein
C2859_07270	ENOG4105VEJ	Heat shock protein
C2859_07275	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
C2859_07285	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
C2859_07330	ENOG4105CNT	hydrolase family 2
C2859_07335	ENOG4106FKC	arabinogalactan endo-1,4-beta-galactosidase
C2859_07350	ENOG4105C26	Dehydrogenase
C2859_07355	ENOG4105C1G	acyl-Coa dehydrogenase
C2859_07360	ENOG4105E39	Enoyl-CoA hydratase
C2859_07365	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
C2859_07370	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
C2859_07385	ENOG4105EMN	RNA polymerase sigma factor
C2859_07395	ENOG4105C0H	protease
C2859_07400	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
C2859_07405	ENOG4105C3F	Signal peptidase i
C2859_07415	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
C2859_07420	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
C2859_07425	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
C2859_07435	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
C2859_07440	ENOG41080ZE	Adenylate cyclase
C2859_07445	ENOG4107ZXU	DSBA oxidoreductase
C2859_07450	ENOG4108QDE	fad dependent oxidoreductase
C2859_07455	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
C2859_07460	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
C2859_07465	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
C2859_07470	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
C2859_07475	ENOG4105VEQ	Cold shock protein
C2859_07495	ENOG4107QRT	dEAD DEAH box helicase
C2859_07500	ENOG4107T0X	DNA ligase
C2859_07510	ENOG4107T0X	DNA ligase
C2859_07525	ENOG4105BZU	Histidine kinase
C2859_07540	ENOG4105CHU	acetyl-coa acetyltransferase
C2859_07565	ENOG4108VKG	metal-dependent hydrolase
C2859_07580	ENOG4105KSC	Transcriptional regulator, TraR DksA family
C2859_07595	ENOG4105DFF	Rod shape-determining protein mreb
C2859_07600	ENOG4108YZY	peptidylprolyl cis-trans isomerase
C2859_07610	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
C2859_07620	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
C2859_07625	ENOG4105F27	Major Facilitator
C2859_07670	ENOG4105M4H	endoribonuclease L-psp
C2859_07675	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
C2859_07690	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
C2859_07715	ENOG4105K6V	RNA polymerase
C2859_07735	ENOG4108R3D	Electron transport complex
C2859_07745	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
C2859_07760	ENOG4105DA5	(ABC) transporter
C2859_07765	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
C2859_07770	ENOG4108IQI	permease
C2859_07775	ENOG4107QK5	Homocysteine s-methyltransferase
C2859_07825	ENOG4108YXA	Membrane
C2859_07840	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
C2859_07850	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
C2859_07855	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
C2859_07860	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
C2859_07865	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
C2859_07870	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
C2859_07880	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C2859_07885	ENOG4105DZP	Membrane-associated zinc metalloprotease
C2859_07890	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
C2859_07895	ENOG4105KNE	Phosphatidate cytidylyltransferase
C2859_07900	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
C2859_07905	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
C2859_07910	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
C2859_07915	ENOG4105BZU	Histidine kinase
C2859_07920	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
C2859_07925	ENOG4105CE9	30S ribosomal protein S2
C2859_07960	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
C2859_07965	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
C2859_07975	ENOG4105KUZ	arsenate reductase
C2859_07980	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
C2859_07985	ENOG4105CAQ	asparagine synthetase
C2859_07995	ENOG4108ESX	Receptor
C2859_08005	ENOG4108UWD	Iron-storage protein
C2859_08010	ENOG4105FQ6	thiopurine methyltransferase
C2859_08025	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C2859_08045	ENOG4105CW7	secretion protein, HlyD family
C2859_08050	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C2859_08070	ENOG4105DUX	Transporter
C2859_08100	ENOG4105DGW	oligopeptidase A
C2859_08110	ENOG4108V06	Glutathione peroxidase
C2859_08115	ENOG4105DP0	ferredoxin-NADP reductase
C2859_08125	ENOG4107GFK	fumarate
C2859_08140	ENOG4105HDD	phospholipase
C2859_08150	ENOG4105VEQ	Cold shock protein
C2859_08165	ENOG4105CUZ	uba thif-type nad fad binding protein
C2859_08170	ENOG4105F8V	Hydrolase, tatD family
C2859_08185	ENOG4105C1G	acyl-Coa dehydrogenase
C2859_08195	ENOG4108K3A	Glutathione S-transferase
C2859_08205	ENOG4105CAQ	asparagine synthetase
C2859_08215	ENOG4105CDU	Replicative dna helicase
C2859_08220	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
C2859_08230	ENOG4105CDV	Ompa motb domain protein
C2859_08240	ENOG4105CR8	Transcriptional regulator
C2859_08275	ENOG4105BZU	Histidine kinase
C2859_08285	ENOG4106TD9	Diguanylate cyclase
C2859_08320	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
C2859_08325	ENOG4108Z1B	Cyclase dehydrase
C2859_08335	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
C2859_08340	ENOG41090R7	Ferric uptake
C2859_08345	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
C2859_08350	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
C2859_08355	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C2859_08360	ENOG4105CFG	Acts as a chaperone (By similarity)
C2859_08365	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
C2859_08375	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
C2859_08405	ENOG4105C5Q	Transcriptional regulator
C2859_08410	ENOG4105BZ1	(ABC) transporter
C2859_08420	ENOG4108URH	decarboxylase
C2859_08430	ENOG4105C7S	Dehydrogenase
C2859_08435	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
C2859_08445	ENOG4105EZE	Cupin 4 family protein
C2859_08455	ENOG4107QTF	adenylosuccinate lyase
C2859_08465	ENOG4105C37	(CBS) domain
C2859_08495	ENOG4105CZV	ABC transporter
C2859_08500	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
C2859_08515	ENOG4108V1T	peptidylprolyl cis-trans isomerase
C2859_08520	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
C2859_08525	ENOG41069P5	Protein slyX homolog
C2859_08540	ENOG4105ETE	Transcriptional regulator (LacI family
C2859_08550	ENOG4105D7K	pfkb domain protein
C2859_08560	ENOG4105C3R	Methionine synthase
C2859_08565	ENOG4105C3R	Methionine synthase
C2859_08575	ENOG4105C1G	acyl-Coa dehydrogenase
C2859_08580	ENOG4105C1G	acyl-Coa dehydrogenase
C2859_08585	ENOG4105C1G	acyl-Coa dehydrogenase
C2859_08590	ENOG4105C1G	acyl-Coa dehydrogenase
C2859_08595	ENOG4105C1G	acyl-Coa dehydrogenase
C2859_08615	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
C2859_08625	ENOG4105C2N	RNA methyltransferase TrmH family group 3
C2859_08630	ENOG4105BZU	Histidine kinase
C2859_08635	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
C2859_08645	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
C2859_08650	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
C2859_08655	ENOG4105E2Z	phosphate ABC transporter (Permease
C2859_08660	ENOG4105C8U	phosphate abc transporter
C2859_08665	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
C2859_08685	ENOG4107B2H	carbonic anhydrase
C2859_08690	ENOG4105CHH	sulfate transporter
C2859_08695	ENOG4105CSM	endonuclease III
C2859_08705	ENOG4105E39	Enoyl-CoA hydratase
C2859_08710	ENOG4108V1T	peptidylprolyl cis-trans isomerase
C2859_08715	ENOG4105P8F	nudix hydrolase
C2859_08720	ENOG4105KHC	sulfurtransferase
C2859_08750	ENOG4105C5H	ABC transporter
C2859_08760	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
C2859_08765	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
C2859_08790	ENOG4105CJB	Exodeoxyribonuclease I
C2859_08800	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
C2859_08805	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
C2859_08815	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
C2859_08820	ENOG41077A9	carbonic anhydrase
C2859_08865	ENOG4105WH1	Two component transcriptional regulator luxr family
C2859_08905	ENOG4105C5S	asparaginyl-tRNA synthetase
C2859_08915	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
C2859_08920	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
C2859_08925	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
C2859_08930	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
C2859_08940	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
C2859_08950	ENOG4105CIH	Imidazole acetol-phosphate transaminase
C2859_08955	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
C2859_08960	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
C2859_08975	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
C2859_08980	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C2859_08985	ENOG4105DZG	Dehydrogenase
C2859_09000	ENOG4105CGP	Urocanate hydratase
C2859_09010	ENOG4105C84	Histidine ammonia-lyase
C2859_09015	ENOG4105CI2	imidazolone-5-propionate hydrolase
C2859_09060	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
C2859_09065	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
C2859_09070	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
C2859_09080	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
C2859_09095	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
C2859_09100	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
C2859_09105	ENOG4105CC0	LysR family Transcriptional regulator
C2859_09120	ENOG4105C8Q	Methyl-accepting chemotaxis
C2859_09145	ENOG4105BZU	Histidine kinase
C2859_09170	ENOG4105KWW	Biogenesis protein
C2859_09175	ENOG4107QX9	Thiol disulfide interChange protein
C2859_09180	ENOG4105DA4	cytochrome c-type biogenesis protein
C2859_09185	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
C2859_09195	ENOG41060IM	Heme exporter protein
C2859_09210	ENOG4105EMN	RNA polymerase sigma factor
C2859_09265	ENOG4105EGZ	biosynthesis protein
C2859_09295	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
C2859_09320	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
C2859_09330	ENOG41079KZ	Major Facilitator Superfamily
C2859_09335	ENOG4105DEN	Luciferase family
C2859_09365	ENOG4105CJ3	phosphate transporter
C2859_09380	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C2859_09390	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
C2859_09395	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
C2859_09405	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
C2859_09410	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
C2859_09415	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
C2859_09420	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
C2859_09425	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
C2859_09430	ENOG4108DG9	Smr protein MutS2
C2859_09435	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
C2859_09440	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
C2859_09445	ENOG4108UM1	dedA family
C2859_09450	ENOG4108K5P	(LipO)protein
C2859_09465	ENOG4105HBR	Rna-binding protein
C2859_09470	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
C2859_09475	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
C2859_09480	ENOG4105EEI	dihydropteroate synthase
C2859_09485	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
C2859_09490	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
C2859_09495	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
C2859_09500	ENOG4107TH8	cina domain protein
C2859_09505	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
C2859_09510	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
C2859_09515	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
C2859_09525	ENOG4105Y3E	Modulates RecA activity (By similarity)
C2859_09530	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
C2859_09535	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
C2859_09575	ENOG4105DH7	May be involved in recombination (By similarity)
C2859_09695	ENOG4106FAK	Endodeoxyribonuclease RusA
C2859_09750	ENOG4105NVB	glycoside hydrolase, family 19
C2859_09895	ENOG4105DFP	Integrase
C2859_09905	ENOG4107SDU	Methyl-accepting chemotaxis
C2859_09915	ENOG4105CWB	LysR family transcriptional Regulator
C2859_09955	ENOG4108IAB	Phoh family
C2859_09960	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C2859_09975	ENOG4107TUS	Dihydrodipicolinate synthase
C2859_09985	ENOG4108Z4U	Ferredoxin
C2859_09990	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
C2859_10000	ENOG4105CXK	mandelate racemase muconate lactonizing
C2859_10005	ENOG4108RTU	Aldolase
C2859_10055	ENOG4105CMG	Carbohydrate kinase
C2859_10060	ENOG4105C93	Xylose Isomerase
C2859_10085	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
C2859_10090	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
C2859_10100	ENOG4105DJ0	Poly(A) Polymerase
C2859_10105	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C2859_10110	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
C2859_10115	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
C2859_10120	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
C2859_10125	ENOG4107QP8	phosphohexose isomerase
C2859_10175	ENOG4105KU2	hydrolase family 5
C2859_10180	ENOG4108UYB	regulatoR
C2859_10190	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
C2859_10195	ENOG410841Q	phosphoesterase PA-phosphatase related protein
C2859_10220	ENOG4108SXK	Transporter Drug Metabolite Exporter family
C2859_10225	ENOG4105D4A	Cell wall formation (By similarity)
C2859_10230	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
C2859_10250	ENOG4105C26	Dehydrogenase
C2859_10310	ENOG4105W5Q	DNA repair protein (RadC
C2859_10380	ENOG4105C79	DNA protecting protein DprA
C2859_10470	ENOG4105EYM	Major Facilitator superfamily
C2859_10530	ENOG4108ZXE	
C2859_10585	ENOG4105CND	Glycosyl transferase, family 2
C2859_10590	ENOG4107BJW	polysaccharide deacetylase
C2859_10665	ENOG4105KAV	tspo and mbr like protein
C2859_10695	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
C2859_10700	ENOG4105CUT	histidyl-tRNA synthetase
C2859_10710	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
C2859_10715	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
C2859_10720	ENOG4105CIH	Imidazole acetol-phosphate transaminase
C2859_10725	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
C2859_10730	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
C2859_10735	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
C2859_10740	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
C2859_10745	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
C2859_10760	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
C2859_10765	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
C2859_10770	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
C2859_10775	ENOG4105CUB	amino acid
C2859_10780	ENOG4105CUB	amino acid
C2859_10790	ENOG4108JQ1	Dehydrogenase
C2859_10795	ENOG4105CQB	FAD linked oxidase domain protein
C2859_10815	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
C2859_10825	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
C2859_10845	ENOG4105CE1	Ferrous iron transport protein b
C2859_10860	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
C2859_10865	ENOG4108RPX	mosc domain containing protein
C2859_10870	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
C2859_10875	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
C2859_10885	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
C2859_10890	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
C2859_10900	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
C2859_10910	ENOG4105DY9	regulatoR
C2859_10920	ENOG4105CRK	lysyL-tRNA synthetase
C2859_10925	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
C2859_10930	ENOG4105BZU	Histidine kinase
C2859_10935	ENOG4105BZU	Histidine kinase
C2859_10940	ENOG4105E39	Enoyl-CoA hydratase
C2859_10945	ENOG4105CEY	Amp-dependent synthetase and ligase
C2859_10955	ENOG4107QM5	aconitate hydratase
C2859_10970	ENOG4107QIJ	Aconitate hydratase 2
C2859_10975	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
C2859_10980	ENOG4105BZU	Histidine kinase
C2859_10985	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
C2859_10990	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
C2859_10995	ENOG4105BZU	Histidine kinase
C2859_11000	ENOG4105C8Q	Methyl-accepting chemotaxis
C2859_11010	ENOG4108V3W	Chemotaxis protein, CheW
C2859_11030	ENOG4105C8Q	Methyl-accepting chemotaxis
C2859_11035	ENOG4105C8Q	Methyl-accepting chemotaxis
C2859_11040	ENOG4105C8Q	Methyl-accepting chemotaxis
C2859_11045	ENOG4105C8Q	Methyl-accepting chemotaxis
C2859_11055	ENOG4105C8Q	Methyl-accepting chemotaxis
C2859_11060	ENOG4105C8Q	Methyl-accepting chemotaxis
C2859_11065	ENOG4105C8Q	Methyl-accepting chemotaxis
C2859_11070	ENOG4105C8Q	Methyl-accepting chemotaxis
C2859_11085	ENOG4105C8Q	Methyl-accepting chemotaxis
C2859_11090	ENOG4105C8Q	Methyl-accepting chemotaxis
C2859_11105	ENOG4105CBS	Chea signal transduction histidine kinase
C2859_11110	ENOG4108VYJ	response regulator receiver protein
C2859_11120	ENOG4108V3W	Chemotaxis protein, CheW
C2859_11125	ENOG4107QJE	Chromosome Partitioning Protein
C2859_11130	ENOG4105ER2	Ompa motb domain protein
C2859_11135	ENOG4105E14	MotA TolQ exbB proton channel
C2859_11230	ENOG4105C4X	radical SAM domain protein
C2859_11245	ENOG4105CBS	Chea signal transduction histidine kinase
C2859_11255	ENOG4108VYJ	response regulator receiver protein
C2859_11260	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C2859_11265	ENOG4107R21	site-determining protein
C2859_11270	ENOG4105FZW	flagellar biosynthesis regulator FlhF
C2859_11275	ENOG4105D7B	Flagellar biosynthesis protein flha
C2859_11280	ENOG4105D00	flagellar biosynthetic protein flhB
C2859_11285	ENOG4105BZU	Histidine kinase
C2859_11290	ENOG4105BZU	Histidine kinase
C2859_11300	ENOG4105BZU	Histidine kinase
C2859_11305	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
C2859_11310	ENOG4105VS8	Flagellar biosynthetic protein fliq
C2859_11320	ENOG4105CN7	Flagellar biosynthetic protein FliP
C2859_11325	ENOG4105K0P	flagellar biosynthesis protein
C2859_11330	ENOG4105DD5	Flagellar motor switch protein
C2859_11335	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
C2859_11355	ENOG4108JIR	Flagellum-specific ATP synthase
C2859_11365	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
C2859_11370	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
C2859_11375	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
C2859_11380	ENOG4107RGC	Glycosyl transferase, family 2
C2859_11385	ENOG4105C74	pyruvyl transferase
C2859_11410	ENOG4105CHR	reductase
C2859_11415	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
C2859_11420	ENOG4108P1X	synthase
C2859_11435	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C2859_11440	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
C2859_11445	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C2859_11465	ENOG4105MQ3	flagellar protein FliS
C2859_11470	ENOG4107W9T	flagellar hook-associated
C2859_11480	ENOG4105DTJ	flagellar hook-associated protein
C2859_11490	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
C2859_11495	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
C2859_11500	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
C2859_11505	ENOG4105CGA	flagellar basal-body rod protein FlgG
C2859_11515	ENOG4108KPB	Flagellar basal-body rod protein FlgF
C2859_11520	ENOG4105BZE	flagellar hook protein, FlgE
C2859_11525	ENOG410822I	Flagellar hook capping protein
C2859_11530	ENOG4108ZC9	flagellar basal-body rod protein flgc
C2859_11540	ENOG4107R88	Chemotaxis protein (CheV)
C2859_11560	ENOG4105BZU	Histidine kinase
C2859_11565	ENOG4105BZU	Histidine kinase
C2859_11575	ENOG4105BZU	Histidine kinase
C2859_11595	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
C2859_11605	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
C2859_11610	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
C2859_11615	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
C2859_11620	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
C2859_11630	ENOG4105C3M	thioredoxin reductase
C2859_11635	ENOG4105CNU	cell division protein FtsK
C2859_11645	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
C2859_11655	ENOG4105D1H	recombination factor protein RarA
C2859_11660	ENOG41082MI	Protein CrcB homolog
C2859_11670	ENOG4105CHU	acetyl-coa acetyltransferase
C2859_11685	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
C2859_11690	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
C2859_11700	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
C2859_11710	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
C2859_11715	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
C2859_11720	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
C2859_11725	ENOG4105D06	uba thif-type nad fad binding protein
C2859_11765	ENOG4105CGK	Exodeoxyribonuclease III
C2859_11775	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
C2859_11780	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
C2859_11790	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
C2859_11820	ENOG4108N8X	transition metal ion binding
C2859_11850	ENOG4108ZXC	Two component transcriptional regulator, luxr family
C2859_11890	ENOG4108HRK	Histidine kinase
C2859_11895	ENOG4105DY9	regulatoR
C2859_11930	ENOG4105W39	Membrane
C2859_11975	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
C2859_11980	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
C2859_11985	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
C2859_11990	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
C2859_12030	ENOG4105RJZ	Transcriptional regulator
C2859_12040	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
C2859_12045	ENOG41090A4	Pterin carbinolamine dehydratase
C2859_12055	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
C2859_12060	ENOG4108NST	exported protein
C2859_12065	ENOG4105EI2	Pseudouridine synthase
C2859_12070	ENOG4105C03	ribonuclease
C2859_12080	ENOG4105C72	UPF0176 protein
C2859_12090	ENOG4108V1T	peptidylprolyl cis-trans isomerase
C2859_12100	ENOG4107QQG	Dehydrogenase
C2859_12160	ENOG4107QJE	Chromosome Partitioning Protein
C2859_12195	ENOG4107YH6	single-stranded DNA-binding protein
C2859_12200	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
C2859_12205	ENOG4105NI8	Cytosine-specific methyltransferase
C2859_12400	ENOG4106NZI	LysR family Transcriptional regulator
C2859_12420	ENOG4105X7H	acyl-CoA dehydrogenase
C2859_12430	ENOG4105E09	nadh pyrophosphatase
C2859_12440	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C2859_12470	ENOG4108KTG	Membrane protein, drug metabolite transporter
C2859_12475	ENOG4105EAC	phosphoserine phosphatase
C2859_12485	ENOG4105EMU	Dehydrogenase
C2859_12495	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
C2859_12500	ENOG4108KB2	LysR family Transcriptional regulator
C2859_12595	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
C2859_12600	ENOG4107QKA	exodeoxyribonuclease V beta
C2859_12610	ENOG4106NZI	LysR family Transcriptional regulator
C2859_12645	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
C2859_12650	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
C2859_12665	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
C2859_12670	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
C2859_12675	ENOG4105BZ1	(ABC) transporter
C2859_12690	ENOG4108EC8	DNA internalization-related competence protein ComEC
C2859_12700	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
C2859_12705	ENOG4105D60	lipoprotein releasing system transmembrane protein
C2859_12715	ENOG410681N	tpr repeat protein
C2859_12740	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
C2859_12765	ENOG4105CHC	glucokinase (EC 2.7.1.2)
C2859_12770	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
C2859_12775	ENOG4105C01	Dihydroxy-acid dehydratase
C2859_12780	ENOG4108UHU	Aldolase
C2859_12810	ENOG4105N7H	Cytochrome
C2859_12855	ENOG4105BZU	Histidine kinase
C2859_12860	ENOG4105BZM	domain protein
C2859_12885	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
C2859_12895	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
C2859_12915	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
C2859_12930	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
C2859_12935	ENOG4108Z6B	deaminase
C2859_12940	ENOG4105KST	dependent repressor
C2859_12945	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
C2859_12965	ENOG4107SFI	Major Facilitator superfamily
C2859_12980	ENOG4105CHJ	isochorismatase hydrolase
C2859_12995	ENOG4105WH1	Two component transcriptional regulator luxr family
C2859_13015	ENOG4105DND	Transcriptional regulator
C2859_13025	ENOG4105EVH	UPF0753 protein
C2859_13030	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
C2859_13120	ENOG4105DFP	Integrase
C2859_13125	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
C2859_13130	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
C2859_13135	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
C2859_13145	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
C2859_13155	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
C2859_13165	ENOG4105ESV	Glycosyl transferase, family 4
C2859_13170	ENOG4105CFV	Tetratricopeptide repeat protein
C2859_13180	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
C2859_13185	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
C2859_13190	ENOG4105CAT	Cytidine monophosphate kinase
C2859_13195	ENOG4105YK5	50S ribosomal protein L36
C2859_13210	ENOG4105DWY	Agmatine deiminase
C2859_13240	ENOG4105DRS	transport system, permease
C2859_13245	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
C2859_13275	ENOG4105K9H	YciI-like protein
C2859_13280	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
C2859_13285	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
C2859_13290	ENOG4105FE9	pseudouridine synthase
C2859_13310	ENOG4105CHM	Aminotransferase
C2859_13315	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
C2859_13320	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
C2859_13325	ENOG41060IM	Heme exporter protein
C2859_13335	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
C2859_13340	ENOG4105DA4	cytochrome c-type biogenesis protein
C2859_13350	ENOG4105KWW	Biogenesis protein
C2859_13355	ENOG4108M1T	Cytochrome c-type biogenesis protein
C2859_13370	ENOG4108JJ8	(ABC) transporter
C2859_13375	ENOG4108JJ9	ABC, transporter
C2859_13380	ENOG4105C4M	(Ubiquinol oxidase) subunit I
C2859_13385	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
C2859_13415	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
C2859_13420	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
C2859_13430	ENOG4105CH7	arginosuccinase
C2859_13435	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
C2859_13445	ENOG4105CAS	nag kinase
C2859_13460	ENOG4105CDH	Citrulline--aspartate ligase
C2859_13465	ENOG4105DBV	ornithine carbamoyltransferase
C2859_13475	ENOG4105C8N	cysteinyl-tRNA synthetase
C2859_13480	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
C2859_13490	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C2859_13495	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
C2859_13500	ENOG4105CD3	dihydroorotase
C2859_13525	ENOG4105CPD	ethanolamine ammonia-lyase
C2859_13530	ENOG4107FQ9	ethanolamine ammonia-lyase
C2859_13585	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
C2859_13590	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
C2859_13595	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
C2859_13605	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
C2859_13610	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
C2859_13615	ENOG4105BZU	Histidine kinase
C2859_13630	ENOG4105ECY	inositol monophosphatase
C2859_13635	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
C2859_13655	ENOG4105C5H	ABC transporter
C2859_13660	ENOG4105C1J	atp-dependent rna helicase
C2859_13665	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
C2859_13670	ENOG4105CNG	UPF0061 protein
C2859_13680	ENOG4108RXX	maleylacetoacetate isomerase
C2859_13685	ENOG4105VEQ	Cold shock protein
C2859_13690	ENOG4108VWS	Yaeq family
C2859_13695	ENOG4105CBX	hi0933 family
C2859_13705	ENOG4105D0M	Protease HtpX homolog
C2859_13710	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
C2859_13715	ENOG4105CHR	reductase
C2859_13740	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
C2859_13745	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
C2859_13750	ENOG4105K8N	protein family UPF0079, ATPase
C2859_13755	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
C2859_13760	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
C2859_13765	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
C2859_13775	ENOG4105E6M	Sulphatase-modifying factor protein
C2859_13795	ENOG4105DQE	DNA ligase
C2859_13820	ENOG4108V3W	Chemotaxis protein, CheW
C2859_13825	ENOG4105C8Q	Methyl-accepting chemotaxis
C2859_13830	ENOG4108VX5	3-methyladenine DNA glycosylase
C2859_13835	ENOG4107QRT	dEAD DEAH box helicase
C2859_13855	ENOG4105KB2	stringent starvation protein b
C2859_13860	ENOG4107MKT	Stringent starvation protein a
C2859_13865	ENOG4105EIX	cytochrome c1
C2859_13870	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
C2859_13875	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
C2859_13885	ENOG4105E4C	Lytic transglycosylase catalytic
C2859_13900	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
C2859_13905	ENOG4105C9A	Phoh family
C2859_13915	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
C2859_13925	ENOG4108JU5	Magnesium and cobalt efflux protein
C2859_13945	ENOG4105D38	putrescine abc transporter
C2859_13950	ENOG4105F38	ABC transporter, permease
C2859_13975	ENOG4107RUE	extracellular solute-binding protein family 1
C2859_13980	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
C2859_13995	ENOG4105CFQ	glutamine synthetase
C2859_14000	ENOG4105CJP	fad dependent oxidoreductase
C2859_14005	ENOG4105BZU	Histidine kinase
C2859_14015	ENOG4105CSH	Transporter
C2859_14030	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
C2859_14035	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
C2859_14040	ENOG4105FCD	Major Facilitator
C2859_14065	ENOG4106BRA	Membrane
C2859_14070	ENOG4105BZU	Histidine kinase
C2859_14075	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
C2859_14080	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C2859_14095	ENOG4105C7I	Dehydrogenase
C2859_14105	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
C2859_14110	ENOG4105BZS	acriflavin resistance protein
C2859_14115	ENOG4108M60	Transcriptional regulator
C2859_14120	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
C2859_14125	ENOG4105DE4	1-phosphofructokinase
C2859_14130	ENOG4105DM4	PTS System
C2859_14155	ENOG4107QT7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
C2859_14160	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
C2859_14165	ENOG4105VIE	preprotein translocase, subunit YajC
C2859_14170	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
C2859_14175	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
C2859_14215	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
C2859_14220	ENOG4105E08	Glycoside hydrolase, family 9
C2859_14225	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
C2859_14230	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
C2859_14245	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
C2859_14250	ENOG4106H78	methyltransferase
C2859_14255	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
C2859_14375	ENOG4107QTZ	amino acid
C2859_14390	ENOG4105DC7	peptidase M24
C2859_14400	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
C2859_14415	ENOG41080HI	glycine oxidase
C2859_14420	ENOG4105CTU	Proline racemase
C2859_14430	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
C2859_14440	ENOG4105CEN	a g-specific adenine glycosylase
C2859_14445	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
C2859_14450	ENOG4105CQZ	Histidine kinase
C2859_14465	ENOG4105DKD	Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity)
C2859_14480	ENOG4105QNF	Outer membrane lipoprotein
C2859_14495	ENOG4105CSU	acyl-Coa dehydrogenase
C2859_14505	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
C2859_14525	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
C2859_14530	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
C2859_14535	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
C2859_14560	ENOG4108NQK	Catalyzes the transfer of a glucuronic acid (GlcA) residue from UDP-glucuronate to mannose-alpha-1,3-glucose-beta- 1,4-glucose-P-P-polyisoprenyl to form the lipid-linked tetrasaccharide GlcA-Man-Glc(2)-PP-Pol, with a glucuronic acid- beta-mannose linkage. Is involved in the biosynthesis of the exopolysaccharide xanthan, since it catalyzes the fourth glycosylation step in the assembly of the pentasaccharide-P-P- polyisoprenyl repeating unit of xanthan. Is unable to use the trisaccharide acceptor freed from the pyrophosphate lipid moiety. Does not show specificity for the lipidic portion of the acceptor. Shows diminished activity when tested with 6-O-acetyl-mannose- alpha-1,3-glucose-beta-1,4-glucose-P-P-polyisoprenyl, a
C2859_14570	ENOG4107Y2G	Glycosyl transferase (Group 1
C2859_14595	ENOG4105D3Q	Sugar transferase
C2859_14615	ENOG4105WJX	transcriptional regulator MERR family
C2859_14620	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
C2859_14625	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
C2859_14630	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
C2859_14635	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
C2859_14640	ENOG41082NX	50s ribosomal protein l35
C2859_14645	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
C2859_14650	ENOG4105C22	threonyL-tRNA synthetase
C2859_14655	ENOG4105ETE	Transcriptional regulator (LacI family
C2859_14690	ENOG4105CG3	alpha amylase, catalytic region
C2859_14810	ENOG4106E4H	Type IV secretory pathway VirB3 family protein
C2859_14830	ENOG4105CMA	conjugation trbi family protein
C2859_14865	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
C2859_14910	ENOG4105EWT	decarboxylase family
C2859_14915	ENOG4108KPZ	tonB-dependent Receptor
C2859_14925	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
C2859_14935	ENOG4105M2J	Glutaredoxin
C2859_14940	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
C2859_14945	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
C2859_14950	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
C2859_14960	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
C2859_14970	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
C2859_14975	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
C2859_14980	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
C2859_14985	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
C2859_14990	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
C2859_14995	ENOG4105CHV	Transcription elongation factor NusA
C2859_15000	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
C2859_15010	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C2859_15015	ENOG4105C8S	subunit m
C2859_15020	ENOG4105D65	subunit l
C2859_15030	ENOG4105DF2	NADH dehydrogenase subunit j
C2859_15035	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C2859_15040	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
C2859_15045	ENOG4107R0R	NADH dehydrogenase subunit g
C2859_15050	ENOG4107QIZ	NADH dehydrogenase
C2859_15055	ENOG4105GKE	subunit e
C2859_15060	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C2859_15065	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
C2859_15070	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C2859_15075	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
C2859_15090	ENOG4105CP7	Triose-phosphate isomerase
C2859_15095	ENOG4107FW0	short-chain dehydrogenase reductase
C2859_15110	ENOG4105BZU	Histidine kinase
C2859_15125	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
C2859_15130	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
C2859_15135	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
C2859_15145	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
C2859_15155	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
C2859_15160	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
C2859_15180	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
C2859_15185	ENOG4105C5I	Dehydrogenase
C2859_15190	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
C2859_15195	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
C2859_15205	ENOG4105DJ4	phosphatidylserine decarboxylase
C2859_15220	ENOG4105D7A	ATP-binding protein
C2859_15225	ENOG4107VIJ	nudix hydrolase
C2859_15245	ENOG4108RRZ	Transcription elongation factor GreB
C2859_15250	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
C2859_15260	ENOG4106A2Z	transcriptional regulator antitoxin, MazE
C2859_15300	ENOG4107RH8	nuclease SbcCD subunit D
C2859_15335	ENOG4105DHP	deoxycytidine triphosphate deaminase
C2859_15365	ENOG4105C9K	Endothelin-converting enzyme 1
C2859_15375	ENOG4105C9K	Endothelin-converting enzyme 1
C2859_15395	ENOG4105DC8	reductase
C2859_15400	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
C2859_15410	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
C2859_15415	ENOG4105K4H	Nlp p60 protein
C2859_15420	ENOG4105K4H	Nlp p60 protein
C2859_15430	ENOG41082K6	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
C2859_15440	ENOG4105G6Z	alkaline phosphatase
C2859_15450	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
C2859_15455	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
C2859_15460	ENOG4105CTB	Polyprenyl synthetase
C2859_15475	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
C2859_15480	ENOG4105N42	UPF0307 protein
C2859_15485	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
C2859_15495	ENOG4105QD6	exported protein
C2859_15500	ENOG4105C03	ribonuclease
C2859_15505	ENOG4108Z03	MAF-like protein
C2859_15510	ENOG4105MPN	Membrane
C2859_15525	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
C2859_15540	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
C2859_15555	ENOG4105C8T	Leucyl-tRNA synthetase
C2859_15565	ENOG4107QR8	Thioredoxin
C2859_15590	ENOG4105WG9	Conserved Protein
C2859_15595	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
C2859_15635	ENOG4105BZ1	(ABC) transporter
C2859_15665	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
C2859_15670	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C2859_15675	ENOG4105BZU	Histidine kinase
C2859_15685	ENOG4105FQP	Beta-lactamase
C2859_15690	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
C2859_15715	ENOG4105FE9	pseudouridine synthase
C2859_15720	ENOG4105BZU	Histidine kinase
C2859_15770	ENOG4105D03	DNA-3-methyladenine glycosylase II
C2859_15785	ENOG4105CMQ	Chloride channel
C2859_15810	ENOG4105UGU	tonB-dependent Receptor
C2859_15830	ENOG4105CVE	Lytic murein transglycosylase
C2859_15850	ENOG4108X1T	PAAR repeat-containing protein
C2859_15900	ENOG4108FN7	Aldo keto reductase
C2859_15905	ENOG4105F27	Major Facilitator
C2859_15910	ENOG4105CC0	LysR family Transcriptional regulator
C2859_15915	ENOG4105CF7	AraC family transcriptional regulator
C2859_15925	ENOG4105EQ2	LysR family Transcriptional regulator
C2859_15930	ENOG4107SET	aldo keto reductase
C2859_15935	ENOG4108JGH	Tetr family transcriptional regulator
C2859_15940	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
C2859_15945	ENOG4105BZS	acriflavin resistance protein
C2859_15950	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
C2859_15960	ENOG4105MYN	Zinc uptake regulation protein
C2859_15965	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
C2859_15990	ENOG4105CT7	inner membrane cred family protein
C2859_16000	ENOG4105EB3	Histidine kinase
C2859_16005	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
C2859_16010	ENOG4105D6S	protein involved in catabolism of external DNA
C2859_16025	ENOG4108JA2	transcriptioN-repair coupling factor
C2859_16035	ENOG4105CBS	Chea signal transduction histidine kinase
C2859_16040	ENOG4105C8Q	Methyl-accepting chemotaxis
C2859_16045	ENOG4108V3W	Chemotaxis protein, CheW
C2859_16050	ENOG4105BZU	Histidine kinase
C2859_16055	ENOG4105BZU	Histidine kinase
C2859_16060	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
C2859_16065	ENOG4107RZC	phospholipase d
C2859_16070	ENOG4105C9K	Endothelin-converting enzyme 1
C2859_16080	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
C2859_16085	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
C2859_16095	ENOG4105EUB	pirin domain protein
C2859_16110	ENOG4105EUB	pirin domain protein
C2859_16115	ENOG4105D22	carbon starvation protein
C2859_16170	ENOG4107XAN	XdhC and CoxI family
C2859_16175	ENOG4105C7W	Xanthine dehydrogenase
C2859_16180	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
C2859_16185	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
C2859_16200	ENOG4108UUM	single-stranded DNA-binding protein
C2859_16205	ENOG4105EAH	synthase
C2859_16215	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
C2859_16230	ENOG4105CFH	Aspartokinase
C2859_16235	ENOG4105JAB	phenazine biosynthesis protein, phzf family
C2859_16240	ENOG4105JAB	phenazine biosynthesis protein, phzf family
C2859_16250	ENOG4108Z9K	Osmotically inducible protein
C2859_16255	ENOG4105CXT	aspartate transcarbamylase
C2859_16260	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
C2859_16265	ENOG4108UJU	UPF0301 protein
C2859_16275	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
C2859_16290	ENOG4105CZX	twitching motility protein
C2859_16295	ENOG4105CZX	twitching motility protein
C2859_16300	ENOG4105DFA	alanine racemase domain protein
C2859_16305	ENOG4105II7	pyrroline-5-carboxylate reductase
C2859_16315	ENOG4105FAA	peptidase M23
C2859_16335	ENOG4108Z0Z	intracellular protease Pfpi family
C2859_16355	ENOG4105C3K	feS assembly ATPase SufC
C2859_16360	ENOG4105JRK	feS assembly protein SufD
C2859_16365	ENOG4105C9B	Cysteine desulfurase
C2859_16380	ENOG4108IU3	tonb-dependent siderophore receptor
C2859_16385	ENOG4107E2E	PKHD-type hydroxylase
C2859_16410	ENOG4105CJ2	(LipO)protein
C2859_16415	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
C2859_16430	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
C2859_16445	ENOG4105EHM	Aminoglycoside phosphotransferase
C2859_16450	ENOG4108S0S	Nucleotidyl transferase
C2859_16460	ENOG4105C02	permease
C2859_16470	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
C2859_16480	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
C2859_16500	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
C2859_16510	ENOG4105C2X	Arabinose 5-phosphate isomerase
C2859_16515	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
C2859_16525	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
C2859_16530	ENOG4108IUZ	ABC transporter
C2859_16535	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C2859_16540	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
C2859_16545	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
C2859_16550	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
C2859_16555	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
C2859_16565	ENOG41080Z8	PHOSPHOCARRIER protein
C2859_16570	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
C2859_16580	ENOG4105CJW	magnesium transporter
C2859_16585	ENOG4107UWA	esterase
C2859_16595	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
C2859_16600	ENOG4105C4M	(Ubiquinol oxidase) subunit I
C2859_16610	ENOG4105C85	amino acid
C2859_16620	ENOG4108NFF	pectate lyase
C2859_16645	ENOG4105CUB	amino acid
C2859_16680	ENOG4105QV4	Tryptophan halogenase
C2859_16735	ENOG4108Z4X	TRANSCRIPTIONal
C2859_16750	ENOG4106032	Glutathionylspermidine synthase
C2859_16775	ENOG4108P9J	Phage shock protein A
C2859_16785	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
C2859_16790	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
C2859_16795	ENOG4105D49	3-dehydroquinate synthase
C2859_16805	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
C2859_16810	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C2859_16815	ENOG4105BZU	Histidine kinase
C2859_16820	ENOG4105BZU	Histidine kinase
C2859_16830	ENOG4105BZU	Histidine kinase
C2859_16835	ENOG4108YYC	ycei family
C2859_16855	ENOG4105EJQ	L-serine dehydratase
C2859_16870	ENOG4105CFH	Aspartokinase
C2859_16875	ENOG4105C28	cystathionine
C2859_16880	ENOG4106TYC	homoserine o-acetyltransferase (EC 2.3.1.31)
C2859_16885	ENOG4105DR5	peptidase
C2859_16890	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
C2859_16895	ENOG4108UT2	hemolysin iii
C2859_16900	ENOG41066T0	asmA family
C2859_16905	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
C2859_16915	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
C2859_16920	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
C2859_16930	ENOG4105D05	Receptor
C2859_16935	ENOG4108IG5	Transcriptional regulator
C2859_16945	ENOG4107QPN	acyl-Coa dehydrogenase
C2859_16970	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
C2859_16975	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
C2859_16995	ENOG4105KK4	UPF0060 membrane protein
C2859_17000	ENOG4105DXN	mazG family
C2859_17005	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
C2859_17010	ENOG4107RK2	ADP-ribose diphosphatase NudE
C2859_17020	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
C2859_17025	ENOG4105CHC	glucokinase (EC 2.7.1.2)
C2859_17040	ENOG4105VRS	hydrolase family 18
C2859_17070	ENOG4107QTZ	amino acid
C2859_17080	ENOG4105F8D	glycoside hydrolase family 4
C2859_17090	ENOG4105CWX	Alpha-1,2-mannosidase
C2859_17130	ENOG4106N3A	copper homeostasis protein cutc
C2859_17150	ENOG4105D9U	N-acetyltransferase
C2859_17165	ENOG4105CBS	Chea signal transduction histidine kinase
C2859_17170	ENOG4105C8Q	Methyl-accepting chemotaxis
C2859_17175	ENOG410807Z	Modulation of CheA activity in response to attractants (Chemotaxis
C2859_17180	ENOG4105M3Z	response regulator
C2859_17185	ENOG4108UNF	response regulator
C2859_17190	ENOG4105D7Z	glutathione synthase
C2859_17200	ENOG41065RQ	ADP-ribosylation crystallin J1
C2859_17205	ENOG41072GX	Peptidase M22 Glycoprotease
C2859_17210	ENOG4105DVT	helicase
C2859_17220	ENOG4105BZ4	penicillin-binding protein
C2859_17240	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
C2859_17250	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
C2859_17255	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
C2859_17260	ENOG4105Z85	coenzyme PQQ synthesis
C2859_17265	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
C2859_17280	ENOG4105CHC	glucokinase (EC 2.7.1.2)
C2859_17295	ENOG4105CQ7	ATP-dependent helicase
C2859_17310	ENOG4105C9U	ATP-dependent DNA helicase RecQ
C2859_17345	ENOG4105C8Q	Methyl-accepting chemotaxis
C2859_17365	ENOG410903D	sensor protein
C2859_17370	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
C2859_17380	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
C2859_17390	ENOG4105KCK	Peptidoglycan-associated lipoprotein
C2859_17395	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
C2859_17405	ENOG4105M8F	Biopolymer transport protein exbD tolR
C2859_17410	ENOG4105E02	MotA TolQ exbB proton channel
C2859_17415	ENOG4107YD3	Thioesterase
C2859_17420	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
C2859_17430	ENOG4105DFH	Transport of potassium into the cell (By similarity)
C2859_17435	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
C2859_17440	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
C2859_17445	ENOG4105CDY	transcriptional regulatory protein
C2859_17460	ENOG4105C9M	aspartyl-trna synthetase
C2859_17580	ENOG4105CVE	Lytic murein transglycosylase
C2859_17595	ENOG4108ISG	Major Facilitator
C2859_17610	ENOG4105HSS	phospholipase C
C2859_17630	ENOG4105ETT	transcriptional Regulator, LysR family
C2859_17640	ENOG4105C5H	ABC transporter
C2859_17645	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
C2859_17660	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
C2859_17665	ENOG4107RNH	Outer membrane receptor FepA
C2859_17680	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
C2859_17705	ENOG4105GAV	receptor
C2859_17730	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
C2859_17750	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
C2859_17755	ENOG4108YZT	Adenosylcobinamide kinase
C2859_17760	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
C2859_17765	ENOG4105EFT	decarboxylase
C2859_17770	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
C2859_17775	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
C2859_17795	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
C2859_17800	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
C2859_17805	ENOG4105E2Y	ABC, transporter
C2859_17810	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
C2859_17815	ENOG4105GVF	(ABC) transporter
C2859_17820	ENOG4105CPC	Aldo Keto reductase
C2859_17825	ENOG4105CPU	Monooxygenase
C2859_17830	ENOG4107ZSV	Receptor
C2859_17835	ENOG41082IR	Excinuclease ABC C subunit domain protein
C2859_17870	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
C2859_17880	ENOG4108K4C	ec 3.1.3.12
C2859_17890	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
C2859_17895	ENOG4105DZG	Dehydrogenase
C2859_17905	ENOG4105C8Q	Methyl-accepting chemotaxis
C2859_17910	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
C2859_17925	ENOG4105C34	Pseudouridine synthase
C2859_17930	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C2859_17940	ENOG4105C4K	Nad synthetase
C2859_17950	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
C2859_17955	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
C2859_17960	ENOG4107TUY	Histidine kinase
C2859_17965	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C2859_17985	ENOG4107QHF	type ii secretion system protein e
C2859_18000	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
C2859_18005	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
C2859_18025	ENOG4105BZU	Histidine kinase
C2859_18030	ENOG4105ETX	regulatoR
C2859_18040	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
C2859_18165	ENOG4105VUH	addiction module killer protein
C2859_18195	ENOG4105CNA	YD repeat protein
C2859_18245	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
C2859_18255	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
C2859_18280	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
C2859_18290	ENOG4105ETE	Transcriptional regulator (LacI family
C2859_18305	ENOG4105EUR	Domain-Containing protein
C2859_18310	ENOG4105J1P	transposase, IS3 IS911 family protein
C2859_18330	ENOG4105BZU	Histidine kinase
C2859_18335	ENOG4108M8H	domain protein
C2859_18350	ENOG41065HY	1,4-beta-cellobiosidase
C2859_18380	ENOG4105EIB	trna rrna methyltransferase
C2859_18390	ENOG4105CD8	aminopeptidase N
C2859_18395	ENOG4105BZS	acriflavin resistance protein
C2859_18405	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
C2859_18410	ENOG4105C11	sulfate adenylyltransferase), subunit 2
C2859_18415	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
C2859_18420	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
C2859_18425	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
C2859_18445	ENOG4105BZU	Histidine kinase
C2859_18460	ENOG4107R11	Transcriptional regulator
C2859_18465	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
C2859_18480	ENOG4108UVJ	appr-1-p processing domain protein
C2859_18485	ENOG4107R1Y	fructose-bisphosphate aldolase
C2859_18500	ENOG4105CA9	Pyruvate kinase
C2859_18510	ENOG4105BZA	Phosphoglycerate kinase
C2859_18535	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
C2859_18545	ENOG4105EIF	outer membrane protein W
C2859_18550	ENOG4105EIF	outer membrane protein W
C2859_18560	ENOG4107S76	domain protein
C2859_18565	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
C2859_18570	ENOG4105E0C	molybdate abc transporter
C2859_18575	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
C2859_18610	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
C2859_18615	ENOG4105DR5	peptidase
C2859_18625	ENOG4105CNM	Receptor
C2859_18630	ENOG4107SKW	Inherit from COG: Alpha beta hydrolase
C2859_18635	ENOG4105CV1	Transketolase (EC 2.2.1.1)
C2859_18640	ENOG4105CK2	sodium dicarboxylate symporter
C2859_18655	ENOG4107QVM	von Willebrand factor, type A
C2859_18675	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
C2859_18680	ENOG4105E4G	Type IV pilus
C2859_18705	ENOG4108JQC	penicillin-binding protein 1A
C2859_18720	ENOG4105NRA	50s ribosomal protein l31 type b
C2859_18725	ENOG4105DU0	nucleoside hydrolase
C2859_18730	ENOG4105CB5	ATP-dependent DNA helicase recG
C2859_18735	ENOG4105KME	endoribonuclease L-psp
C2859_18740	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
C2859_18745	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
C2859_18750	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
C2859_18755	ENOG4105DSJ	YicC domain protein
C2859_18760	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
C2859_18770	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
C2859_18775	ENOG4105CSA	Coproporphyrinogen iii oxidase
C2859_18790	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
C2859_18800	ENOG4107RAQ	aminopeptidase
C2859_18815	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
C2859_18825	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
C2859_18835	ENOG4105E66	phosphoriboisomerase A
C2859_18845	ENOG41063JG	Transcriptional regulator
C2859_18850	ENOG4105VCQ	rubredoxin
C2859_18855	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
C2859_18870	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
C2859_18875	ENOG41061ZR	Transcriptional regulator
C2859_18890	ENOG4105CIH	Imidazole acetol-phosphate transaminase
C2859_18920	ENOG4105C8Y	Acetylornithine aminotransferase
C2859_18925	ENOG4105EYW	Ion transport protein
C2859_18945	ENOG410841Q	phosphoesterase PA-phosphatase related protein
C2859_18950	ENOG4105FFC	UPF0187 protein
C2859_18960	ENOG4105DFU	Cell wall formation (By similarity)
C2859_18965	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
C2859_18980	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
C2859_18990	ENOG4105F0N	pyrophosphate phospho-hydrolase
C2859_19005	ENOG4105ECQ	AraC Family Transcriptional Regulator
C2859_19015	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
C2859_19035	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
C2859_19040	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
C2859_19055	ENOG4105C7B	Threonine dehydratase
C2859_19060	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
C2859_19070	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
C2859_19075	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
C2859_19080	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
C2859_19085	ENOG4108MP6	LysR family Transcriptional regulator
C2859_19100	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
C2859_19105	ENOG4105DFG	type I secretion outer membrane protein
C2859_19110	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
C2859_19120	ENOG4105D1S	lipid A biosynthesis
C2859_19150	ENOG4105C6K	Malic enzyme
C2859_19155	ENOG4105CK2	sodium dicarboxylate symporter
C2859_19165	ENOG4105CQZ	Histidine kinase
C2859_19170	ENOG4105CSH	Transporter
C2859_19180	ENOG4105F04	LysR family Transcriptional regulator
C2859_19185	ENOG4105CPC	Aldo Keto reductase
C2859_19200	ENOG4105WH1	Two component transcriptional regulator luxr family
C2859_19205	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
C2859_19210	ENOG4105DHQ	Histidine kinase
C2859_19230	ENOG4105D4T	Citrate transporter
C2859_19235	ENOG4105CHR	reductase
C2859_19255	ENOG4107QW3	Sucrose phosphorylase
C2859_19270	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
C2859_19305	ENOG4105CNM	Receptor
C2859_19330	ENOG41069H0	dihydroorotase EC 3.5.2.3
C2859_19335	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
C2859_19360	ENOG4108RMV	DegV Family
C2859_19365	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
C2859_19395	ENOG4105EJG	cellulose synthase
C2859_19400	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
C2859_19405	ENOG4107EEX	Cellulose synthase regulator protein
C2859_19410	ENOG4107QZ7	Cellulose synthase catalytic subunit
C2859_19425	ENOG4107RH7	Nicotinate phosphoribosyltransferase
C2859_19480	ENOG4106S9K	Transcriptional regulator
C2859_19490	ENOG4105GVR	general secretion pathway protein D
C2859_19500	ENOG410678M	general secretion pathway protein M
C2859_19505	ENOG41090VX	general secretion pathway protein L
C2859_19510	ENOG4105UV2	general secretion pathway protein K
C2859_19515	ENOG41069G9	General secretion pathway protein J
C2859_19525	ENOG4105WMT	general secretion pathway protein h
C2859_19535	ENOG4105D7Q	type ii secretion system
C2859_19540	ENOG4107QHF	type ii secretion system protein e
C2859_19545	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
C2859_19550	ENOG4105EUR	Domain-Containing protein
C2859_19555	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
C2859_19560	ENOG4105EUR	Domain-Containing protein
C2859_19570	ENOG4108ETH	Formylglycinamide ribotide synthetase
C2859_19585	ENOG4105T95	Thiol disulfide interChange protein
C2859_19600	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
C2859_19615	ENOG4108K5H	permease YjgP YjgQ family protein
C2859_19625	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
C2859_19640	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
C2859_19670	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
C2859_19680	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
C2859_19685	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
C2859_19700	ENOG4105DHJ	ABC, transporter
C2859_19705	ENOG4108SNX	Mammalian cell entry related domain protein
C2859_19720	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
C2859_19735	ENOG4107QKV	phosphomannomutase
C2859_19740	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
C2859_19750	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
C2859_19755	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
C2859_19770	ENOG4105BZJ	Electron transfer flavoprotein
C2859_19775	ENOG4105C10	Electron transfer flavoprotein
C2859_19810	ENOG4108DMA	Nad-dependent epimerase dehydratase
C2859_19815	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
C2859_19820	ENOG4105CGN	Glycosyl transferase (Group 1
C2859_19830	ENOG4105EY8	ABC transporter
C2859_19840	ENOG4107STW	synthase
C2859_19850	ENOG4105C28	cystathionine
C2859_19875	ENOG4105CZX	twitching motility protein
C2859_19880	ENOG4108RXX	maleylacetoacetate isomerase
C2859_19895	ENOG4105C1J	atp-dependent rna helicase
C2859_19905	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
C2859_19915	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
C2859_19925	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
C2859_19945	ENOG4105NIV	Esterase
C2859_19950	ENOG4107RNH	Outer membrane receptor FepA
C2859_19955	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
C2859_19960	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
C2859_19965	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
C2859_19980	ENOG4105DGW	oligopeptidase A
C2859_20035	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
C2859_20040	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
C2859_20045	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
C2859_20050	ENOG4107RBB	ABC transporter, permease
C2859_20065	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C2859_20070	ENOG4105BZU	Histidine kinase
C2859_20075	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
C2859_20090	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
C2859_20095	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
C2859_20100	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
C2859_20105	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
C2859_20110	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
C2859_20115	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
C2859_20120	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
C2859_20125	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
C2859_20145	ENOG4107QN2	dihydrolipoyl dehydrogenase
C2859_20155	ENOG4107QSN	dihydrolipoamide acetyltransferase
C2859_20190	ENOG4105D01	(LipO)protein
C2859_20195	ENOG4108UMI	ABC transporter, permease
C2859_20200	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
C2859_20205	ENOG4108EHX	EamA-like transporter family
C2859_20210	ENOG4108VPT	UPF0234 protein
C2859_20220	ENOG4105BZU	Histidine kinase
C2859_20240	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
C2859_20245	ENOG4107YBY	Hydrolase
C2859_20250	ENOG4105I08	Pseudouridine synthase
C2859_20255	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
C2859_20275	ENOG4105BZU	Histidine kinase
C2859_20295	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
C2859_20300	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
C2859_20305	ENOG4105EW9	transcriptional regulator AsnC family
C2859_20330	ENOG4107RD7	Flagellar Motor Protein, MotA
C2859_20335	ENOG4105ER2	Ompa motb domain protein
C2859_20360	ENOG4105E3A	(ABC) transporter
C2859_20365	ENOG4105DA5	(ABC) transporter
C2859_20370	ENOG4105EEQ	Na H antiporter
C2859_20385	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
C2859_20395	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
C2859_20405	ENOG4105CBN	LysR family transcriptional regulator
C2859_20415	ENOG4105CPC	Aldo Keto reductase
C2859_20430	ENOG4105C9K	Endothelin-converting enzyme 1
C2859_20450	ENOG4107QTZ	amino acid
C2859_20460	ENOG4108VAC	response regulator
C2859_20465	ENOG4105C2F	Histidine kinase
C2859_20490	ENOG4108Z9Z	response to DNA damage stimulus
C2859_20495	ENOG4105WEF	catalase
C2859_20515	ENOG4105BZU	Histidine kinase
C2859_20530	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C2859_20545	ENOG4105C4M	(Ubiquinol oxidase) subunit I
C2859_20550	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
C2859_20565	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
C2859_20570	ENOG4105CMR	udp-glucose 4-epimerase
C2859_20590	ENOG4105BZ1	(ABC) transporter
C2859_20605	ENOG4105E2A	Dehydrogenase
C2859_20665	ENOG4105CIG	ABC transporter
C2859_20680	ENOG4108UQ8	endoribonuclease L-psp
C2859_20710	ENOG4105HEI	LysR family (Transcriptional regulator
C2859_20715	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
C2859_20890	ENOG4105ED4	portal protein
C2859_20935	ENOG4105NVB	glycoside hydrolase, family 19
C2859_21140	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C2859_21145	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
C2859_21150	ENOG4105D1S	lipid A biosynthesis
C2859_21160	ENOG4108Z7F	N-acetyltransferase
C2859_21205	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
C2859_21210	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
C2859_21215	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
C2859_21220	ENOG4108WZM	domain protein
C2859_21225	ENOG4105C79	DNA protecting protein DprA
C2859_21230	ENOG4108RPN	Protein smg homolog
C2859_21245	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
C2859_21250	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
C2859_21265	ENOG4107ZQV	short-chain dehydrogenase reductase
C2859_21275	ENOG4105D07	Signal peptide peptidase, SppA
C2859_21280	ENOG4107QI1	Mate efflux family protein
C2859_21300	ENOG4105C25	Primosomal protein n'
C2859_21305	ENOG4108TGY	Glutathione S-transferase
C2859_21325	ENOG4105EN6	Membrane
C2859_21330	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C2859_21335	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
C2859_21340	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
C2859_21345	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
C2859_21350	ENOG4105CAK	Cell division ATP-binding protein ftsE
C2859_21355	ENOG4105C1J	atp-dependent rna helicase
C2859_21360	ENOG4105K63	Thioredoxin
C2859_21365	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
C2859_21370	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
C2859_21375	ENOG4105ETT	transcriptional Regulator, LysR family
C2859_21385	ENOG4105E9K	Isocitrate dehydrogenase
C2859_21395	ENOG4109066	lysm domain bon superfamily protein
C2859_21400	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
C2859_21405	ENOG4105CH2	amidohydrolase
C2859_21410	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
C2859_21415	ENOG4105BZS	acriflavin resistance protein
C2859_21425	ENOG4105E32	cytoplasmic protein
C2859_21470	ENOG4108UQS	dipeptidase
C2859_21475	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
C2859_21485	ENOG4105DTQ	mandelate racemase muconate lactonizing
C2859_21495	ENOG4105D5Q	Arginine ornithine antiporter
C2859_21510	ENOG4108Z12	YiaAB two helix domain-containing protein
C2859_21520	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
C2859_21525	ENOG4107ZVW	dihydroneopterin aldolase
C2859_21530	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
C2859_21535	ENOG4105VCC	30S ribosomal protein S21
C2859_21540	ENOG4105KTH	gatB Yqey
C2859_21550	ENOG4107S2Z	UPF0761 membrane protein
C2859_21555	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
C2859_21560	ENOG4105DHU	Bile acid
C2859_21570	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
C2859_21595	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
C2859_21600	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
C2859_21615	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
C2859_21625	ENOG4105C26	Dehydrogenase
C2859_21660	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
C2859_21665	ENOG4105DR5	peptidase
C2859_21670	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
C2859_21680	ENOG4105EYM	Major Facilitator superfamily
C2859_21685	ENOG4105CGK	Exodeoxyribonuclease III
C2859_21690	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
C2859_21700	ENOG4107QJE	Chromosome Partitioning Protein
C2859_21705	ENOG4105FA0	parb-like partition protein
C2859_21725	ENOG4105CKK	Glycosyl transferase, family 2
C2859_21745	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
C2859_21750	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
C2859_21755	ENOG4105W5Q	DNA repair protein (RadC
C2859_21760	ENOG4105C75	arginyL-tRNA synthetase
C2859_21775	ENOG4105EMU	Dehydrogenase
C2859_21790	ENOG4105CEY	Amp-dependent synthetase and ligase
C2859_21795	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
C2859_21800	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
C2859_21825	ENOG4105CPE	K01197 hyaluronoglucosaminidase EC 3.2.1.35
C2859_21835	ENOG4108YZA	Nitrogen regulatory protein pii
C2859_21840	ENOG4105W0Z	cytoplasmic protein
C2859_21845	ENOG4105C0P	Mg chelatase subunit ChlI
C2859_21860	ENOG41066DG	(EAL) domain protein
C2859_21875	ENOG4105EJ2	Transcriptional regulator
C2859_21895	ENOG4105E0Y	RtcB Protein
C2859_21930	ENOG4105ECP	epimerase
C2859_21935	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
C2859_21940	ENOG4105DHQ	Histidine kinase
C2859_21970	ENOG4105C0H	protease
C2859_21990	ENOG4105DSF	transport protein
C2859_21995	ENOG4107URF	beta-phospho-glucomutase
C2859_22000	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
C2859_22015	ENOG4107VGR	Catalase
C2859_22030	ENOG4108S01	response regulator
C2859_22035	ENOG4108ZGX	Histidine kinase
C2859_22040	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
C2859_22045	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C2859_22070	ENOG4105FDR	Membrane
C2859_22090	ENOG4108NNI	Beta-lactamase domain-containing protein
C2859_22095	ENOG4105C31	Tryptophanyl-tRNA synthetase
C2859_22100	ENOG4105VDW	Csbd family
C2859_22185	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
C2859_22215	ENOG4105EB3	Histidine kinase
C2859_22220	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
C2859_22230	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
C2859_22250	ENOG4105CH6	catalase
C2859_22260	ENOG4105DVT	helicase
C2859_22275	ENOG4105E2X	shikimate dehydrogenase
C2859_22310	ENOG4105D52	delta-aminolevulinic acid dehydratase
C2859_22335	ENOG4105CYM	Glutathione S-transferase
C2859_22360	ENOG4105QV4	Tryptophan halogenase
C2859_22375	ENOG4108IUW	ABC transporter
C2859_22385	ENOG4105VZ8	Transcriptional regulator
C2859_22405	ENOG4105PGM	cation diffusion facilitator family transporter
C2859_22415	ENOG4105E0K	tonB-dependent siderophore receptor
C2859_22425	ENOG4105ECQ	AraC Family Transcriptional Regulator
C2859_22430	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
C2859_22435	ENOG4105DA5	(ABC) transporter
C2859_22440	ENOG4105E3A	(ABC) transporter
C2859_22450	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
C2859_22485	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
C2859_22495	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
C2859_22510	ENOG4105CD5	CoA-binding domain protein
C2859_22515	ENOG4105CJW	magnesium transporter
C2859_22535	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
C2859_22540	ENOG4105BZP	glycoside hydrolase 15-related
C2859_22560	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
C2859_22570	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
C2859_22615	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
C2859_22620	ENOG4105E9Q	Acyl-transferase
C2859_22630	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
C2859_22660	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
C2859_22680	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
C2859_22690	ENOG4105C2M	dna polymerase I
C2859_22720	ENOG4105D9P	serine threonine protein kinase
C2859_22725	ENOG4108ZF3	Phosphatase
C2859_22760	ENOG4105CS6	Rhs element vgr protein
C2859_22805	ENOG4105D6F	Phosphatase
C2859_22850	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
C2859_22875	ENOG4108WC9	type VI secretion system effector, hcp1 family
C2859_22905	ENOG4105C4R	Atp-dependent dna helicase
C2859_22920	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
C2859_22925	ENOG4108KB2	LysR family Transcriptional regulator
C2859_22930	ENOG4105JSC	dimethylmenaquinone methyltransferase
C2859_22945	ENOG4105KHM	amidohydrolase 2
C2859_22950	ENOG4105W0E	50S ribosomal protein L33
C2859_22955	ENOG4105KDC	50s ribosomal protein l28
C2859_22970	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
C2859_22990	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
C2859_22995	ENOG4105DGI	Alkaline phosphatase
C2859_23020	ENOG4105CGK	Exodeoxyribonuclease III
C2859_23025	ENOG4105E2R	ROK family
C2859_23035	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
C2859_23045	ENOG4107QN1	sodium solute
C2859_23050	ENOG41062QD	Membrane
C2859_23060	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
C2859_23090	ENOG4105DSG	hydrolase family 43
C2859_23110	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
C2859_23115	ENOG4105ERH	Fumarylacetoacetate hydrolase
C2859_23125	ENOG4105DIA	mandelate racemase muconate lactonizing
C2859_23130	ENOG4105QJH	Domain of unknown function (DUF718)
C2859_23135	ENOG4105EDR	glucose galactose transporter
C2859_23140	ENOG4108K2P	TRANSCRIPTIONal
C2859_23145	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
C2859_23150	ENOG4105BZU	Histidine kinase
C2859_23165	ENOG4105E2V	Glycosyltransferase 36
C2859_23170	ENOG4105CT4	transporter
C2859_23175	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
C2859_23205	ENOG4105MA0	exported protein
C2859_23210	ENOG4105CFU	surface antigen
C2859_23230	ENOG4108JJA	ABC, transporter
C2859_23235	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
C2859_23240	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
C2859_23245	ENOG4107QHF	type ii secretion system protein e
C2859_23265	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
C2859_23275	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
C2859_23280	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
C2859_23295	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
C2859_23320	ENOG4105DH7	May be involved in recombination (By similarity)
C2859_23325	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
C2859_23335	ENOG4105C93	Xylose Isomerase
C2859_23340	ENOG4105ETE	Transcriptional regulator (LacI family
C2859_23345	ENOG4105D0H	Alpha-glucuronidase (EC 3.2.1.139)
C2859_23355	ENOG4105CXK	mandelate racemase muconate lactonizing
C2859_23370	ENOG4105DEI	Mannitol dehydrogenase
C2859_23420	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
C2859_23455	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
C2859_23460	ENOG4105CNT	hydrolase family 2
C2859_23465	ENOG4105D2H	Uronic isomerase
C2859_23495	ENOG4105CT4	transporter
C2859_23500	ENOG4105DT9	hydrolase family 43
C2859_23535	ENOG4105E55	glycerol-3-phosphate acyltransferase
C2859_23550	ENOG4105ETE	Transcriptional regulator (LacI family
C2859_23565	ENOG4105QV4	Tryptophan halogenase
C2859_23570	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
C2859_23575	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
C2859_23585	ENOG4108YXG	UPF0502 protein
C2859_23595	ENOG4105KNA	-acetyltransferase
C2859_23600	ENOG4105C4R	Atp-dependent dna helicase
C2859_23605	ENOG4107104	thymidine kinase
C2859_23610	ENOG4105BZU	Histidine kinase
C2859_23615	ENOG4105DJ9	glucan biosynthesis protein
C2859_23625	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
C2859_23655	ENOG4105DKK	Benzoate
C2859_23675	ENOG4105DSB	aldose 1-epimerase
C2859_23685	ENOG4105K5B	UPF0225 protein
C2859_23690	ENOG4105EJ9	Membrane
C2859_23710	ENOG4105EUJ	GTP cyclohydrolase i
C2859_23720	ENOG4105ZQC	membrane protein AaeX
C2859_23725	ENOG4105Y49	secretion protein, HlyD family
C2859_23735	ENOG4105DR8	Membrane
C2859_23740	ENOG4105CSH	Transporter
C2859_23750	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
C2859_23815	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
C2859_23855	ENOG4107QKA	exodeoxyribonuclease V beta
C2859_23860	ENOG4105DSY	exodeoxyribonuclease V, gamma
C2859_23875	ENOG4105DHJ	ABC, transporter
C2859_23880	ENOG4105CY3	ABC transporter, permease
C2859_23885	ENOG4107PE3	Mammalian cell entry related domain protein
C2859_23900	ENOG410903C	(LipO)protein
C2859_23910	ENOG4108V06	Glutathione peroxidase
C2859_23920	ENOG4107QSV	RmuC domain protein
C2859_23925	ENOG4105CIS	alcohol dehydrogenase
C2859_23930	ENOG4105EJC	lysr family transcriptional regulator
C2859_23945	ENOG4108TGY	Glutathione S-transferase
C2859_23955	ENOG4105CUB	amino acid
C2859_23960	ENOG4105CWX	Alpha-1,2-mannosidase
C2859_23970	ENOG4105NRM	Membrane
C2859_23975	ENOG4105BZU	Histidine kinase
C2859_23980	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
C2859_23985	ENOG4105BZW	Glycerate kinase
C2859_23990	ENOG4105CSP	Major Facilitator Superfamily
C2859_24005	ENOG4105DR4	Methyltransferase
C2859_24015	ENOG4105DU1	integral membrane protein, terc
C2859_24030	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
C2859_24045	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
C2859_24050	ENOG4108ZJ4	polysaccharide deacetylase
C2859_24055	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
C2859_24060	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
C2859_24095	ENOG4108C33	Resolvase
C2859_24105	ENOG4105C0H	protease