locus-tag	class	description
CIW72_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
CIW72_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
CIW72_00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
CIW72_00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CIW72_00030	ENOG4108K0D	peptidase, M48
CIW72_00060	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
CIW72_00070	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
CIW72_00115	ENOG4105CN1	protease
CIW72_00120	ENOG41063SB	peptidase
CIW72_00130	ENOG4107VAM	peptidase, m28
CIW72_00170	ENOG4105DQ4	alcohol dehydrogenase
CIW72_00175	ENOG4105BZ8	glutamate synthase
CIW72_00180	ENOG4105CBC	glutamate synthase
CIW72_00230	ENOG4105D3Q	Sugar transferase
CIW72_00235	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
CIW72_00245	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
CIW72_00250	ENOG4107RA4	Glycosyl transferase (Group 1
CIW72_00270	ENOG4105CAQ	asparagine synthetase
CIW72_00285	ENOG4105CMR	udp-glucose 4-epimerase
CIW72_00300	ENOG4105BZ1	(ABC) transporter
CIW72_00330	ENOG4107W2Z	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) (By similarity)
CIW72_00425	ENOG4108I5C	dEAD DEAH box helicase
CIW72_00430	ENOG4108UT2	hemolysin iii
CIW72_00450	ENOG4107FW0	short-chain dehydrogenase reductase
CIW72_00455	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
CIW72_00470	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
CIW72_00500	ENOG41067RQ	csbd family
CIW72_00520	ENOG4105D4Y	metalloprotease
CIW72_00550	ENOG4105K63	Thioredoxin
CIW72_00600	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
CIW72_00630	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CIW72_00635	ENOG4105CGF	Aromatic amino acid aminotransferase
CIW72_00640	ENOG4105CHB	tonB-dependent Receptor
CIW72_00705	ENOG4105DMF	Dehydrogenase
CIW72_00720	ENOG4105BZU	Histidine kinase
CIW72_00725	ENOG4108S01	response regulator
CIW72_00745	ENOG4108M3R	transcriptional activator CadC
CIW72_00750	ENOG4105RKW	reductase (By
CIW72_00805	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
CIW72_00810	ENOG4105CG3	alpha amylase, catalytic region
CIW72_00815	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
CIW72_00830	ENOG4105EBR	Carboxylesterase
CIW72_00845	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
CIW72_00855	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CIW72_00860	ENOG4105DSG	hydrolase family 43
CIW72_00865	ENOG4105ETE	Transcriptional regulator (LacI family
CIW72_00870	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
CIW72_00875	ENOG4105CHR	reductase
CIW72_00885	ENOG4107TDE	lipolytic protein G-D-S-L family
CIW72_00900	ENOG4105MIR	Phenylalanine 4-monooxygenase
CIW72_00905	ENOG4108YXU	transcriptional regulator AsnC family
CIW72_00910	ENOG4105CNM	Receptor
CIW72_00915	ENOG4105D78	K07001 NTE family protein
CIW72_00925	ENOG4105DKW	ABC transporter
CIW72_00940	ENOG4108IJ8	ABC transporter
CIW72_00945	ENOG4105E90	ABC transporter
CIW72_01000	ENOG4105D1F	ATP-binding protein
CIW72_01005	ENOG4105M4E	phosphohistidine phosphatase, SixA
CIW72_01015	ENOG4107RZC	phospholipase d
CIW72_01020	ENOG4105KA0	thioesterase Superfamily protein
CIW72_01045	ENOG4108V1U	phospholipid-binding protein
CIW72_01055	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
CIW72_01060	ENOG4105C5F	glutamine synthetase
CIW72_01070	ENOG4105BZU	Histidine kinase
CIW72_01075	ENOG4105CUX	Signal transduction histidine kinase
CIW72_01080	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CIW72_01085	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
CIW72_01090	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
CIW72_01105	ENOG4105CHU	acetyl-coa acetyltransferase
CIW72_01140	ENOG4107YZP	Rhodanese domain protein
CIW72_01145	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
CIW72_01150	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
CIW72_01165	ENOG4105C7K	acetolactate synthase
CIW72_01170	ENOG4108TQ9	Histidine kinase
CIW72_01175	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CIW72_01195	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
CIW72_01210	ENOG4105E2T	synthase III
CIW72_01215	ENOG4107R3N	Filamentation induced by cAMP protein fic
CIW72_01220	ENOG4108J2P	Alpha beta hydrolase fold
CIW72_01225	ENOG4105PI0	Ferredoxin
CIW72_01230	ENOG410680H	amp-dependent synthetase and ligase
CIW72_01240	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
CIW72_01255	ENOG4105CPF	Cell wall formation (By similarity)
CIW72_01265	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
CIW72_01275	ENOG4105DR9	pseudouridine synthase
CIW72_01285	ENOG4108YZN	class I peptide chain release factor
CIW72_01295	ENOG4105D44	asparaginase
CIW72_01300	ENOG4105DGW	oligopeptidase A
CIW72_01335	ENOG4105DUM	transcriptional regulator, lysR family
CIW72_01340	ENOG4107QP3	malate synthase g
CIW72_01350	ENOG4105BZU	Histidine kinase
CIW72_01380	ENOG4107QX3	carboxylase
CIW72_01385	ENOG4105C1G	acyl-Coa dehydrogenase
CIW72_01455	ENOG4108TZV	Membrane
CIW72_01465	ENOG4105D6Z	AFG1 family ATPase
CIW72_01470	ENOG4105K56	Transcriptional regulator
CIW72_01475	ENOG4108ZHJ	Organic hydroperoxide resistance protein
CIW72_01505	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
CIW72_01520	ENOG4108R99	pseudouridine synthase
CIW72_01525	ENOG4108KPZ	tonB-dependent Receptor
CIW72_01535	ENOG4105CQ7	ATP-dependent helicase
CIW72_01545	ENOG4108W15	Protein of unknown function (DUF1456)
CIW72_01555	ENOG4105E1J	oxidoreductase
CIW72_01575	ENOG4105C5R	Aminotransferase
CIW72_01585	ENOG4105EQ2	LysR family Transcriptional regulator
CIW72_01590	ENOG4107RTG	Major Facilitator superfamily
CIW72_01600	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
CIW72_01610	ENOG4105DU0	nucleoside hydrolase
CIW72_01620	ENOG4105C7N	Xanthine uracil vitamin C permease
CIW72_01640	ENOG4105ETT	transcriptional Regulator, LysR family
CIW72_01645	ENOG4105F8V	Hydrolase, tatD family
CIW72_01660	ENOG4106NZI	LysR family Transcriptional regulator
CIW72_01665	ENOG4105D94	Major Facilitator Superfamily
CIW72_01680	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
CIW72_01685	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
CIW72_01705	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
CIW72_01710	ENOG4105EB3	Histidine kinase
CIW72_01715	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
CIW72_01725	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
CIW72_01740	ENOG4105WPN	DNA integration recombination invertion protein
CIW72_01745	ENOG4105DZ2	Transcriptional regulator
CIW72_01750	ENOG4108UZX	fmn reductase
CIW72_01765	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
CIW72_01780	ENOG4105ECR	NmrA family
CIW72_01840	ENOG4105C01	Dihydroxy-acid dehydratase
CIW72_01855	ENOG4108Z0R	Transferase
CIW72_01865	ENOG4105D2S	major facilitator superfamily
CIW72_01870	ENOG4105CPI	Metal Dependent Phosphohydrolase
CIW72_01900	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
CIW72_01910	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
CIW72_01915	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
CIW72_01920	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
CIW72_01925	ENOG4105E98	transcriptional regulator DeoR family
CIW72_01950	ENOG4105CHU	acetyl-coa acetyltransferase
CIW72_01960	ENOG4105EU7	Protocatechuate 3,4-dioxygenase, beta
CIW72_01965	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
CIW72_01970	ENOG4105F2Z	3-oxoadipate enol-lactonase
CIW72_01975	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
CIW72_01985	ENOG4107HP6	Transcriptional regulator
CIW72_02000	ENOG4105MH3	Protein of unknown function (DUF2490)
CIW72_02005	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
CIW72_02045	ENOG4105DTD	Dehydrogenase
CIW72_02050	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
CIW72_02060	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
CIW72_02065	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
CIW72_02070	ENOG41081UC	Inherit from COG: Competence protein
CIW72_02075	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
CIW72_02130	ENOG4105VS8	Flagellar biosynthetic protein fliq
CIW72_02150	ENOG4108HR8	type iii secretion
CIW72_02170	ENOG4107Y59	type iii secretion
CIW72_02185	ENOG4108JIR	Flagellum-specific ATP synthase
CIW72_02195	ENOG4108TN6	type iii secretion
CIW72_02200	ENOG4105K44	type iii secretion
CIW72_02210	ENOG4105FTC	Lytic transglycosylase catalytic
CIW72_02225	ENOG4105EGS	Mechanosensitive ion channel
CIW72_02230	ENOG4107RES	phosphoglycerol transferase I
CIW72_02245	ENOG4105CKW	Inner membrane protein yedI
CIW72_02250	ENOG4105BZU	Histidine kinase
CIW72_02255	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
CIW72_02260	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
CIW72_02265	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
CIW72_02290	ENOG4105K4T	epimerase
CIW72_02295	ENOG4107ZQV	short-chain dehydrogenase reductase
CIW72_02335	ENOG4105CHR	reductase
CIW72_02345	ENOG4105C1J	atp-dependent rna helicase
CIW72_02350	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
CIW72_02360	ENOG4105CPP	Dehydrogenase, E1 component
CIW72_02365	ENOG4107RUY	(E1 component), alpha subunit
CIW72_02375	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
CIW72_02380	ENOG4105DUX	Transporter
CIW72_02395	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
CIW72_02400	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
CIW72_02405	ENOG4105F1J	Homogentisate 1,2-dioxygenase
CIW72_02425	ENOG4105KJM	monovalent cation h antiporter subunit g
CIW72_02430	ENOG4105W4C	monovalent cation H antiporter subunit F
CIW72_02440	ENOG4107R4Z	monovalent cation h antiporter subunit d
CIW72_02445	ENOG4108ZE9	Monovalent cation H antiporter subunit C
CIW72_02450	ENOG4105D65	subunit l
CIW72_02470	ENOG4105NVB	glycoside hydrolase, family 19
CIW72_02490	ENOG4105C8V	SAICAR synthetase
CIW72_02495	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
CIW72_02510	ENOG4105KD7	acetyltransferase
CIW72_02605	ENOG4107TE5	Lipid kinase
CIW72_02610	ENOG4105CRQ	synthase (Component I)
CIW72_02620	ENOG4105DDQ	anthranilate synthase
CIW72_02630	ENOG4108I0Q	anthranilate phosphoribosyltransferase
CIW72_02635	ENOG4105DK0	Indole-3-glycerol phosphate synthase
CIW72_02645	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
CIW72_02650	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
CIW72_02665	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
CIW72_02670	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
CIW72_02675	ENOG4108UJD	30S ribosomal protein S9
CIW72_02690	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
CIW72_02700	ENOG4108UQY	Iron-storage protein
CIW72_02705	ENOG4105BZU	Histidine kinase
CIW72_02730	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
CIW72_02750	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
CIW72_02770	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
CIW72_02785	ENOG4105EM2	membrane
CIW72_02795	ENOG4105C12	Phosphoribosylglycinamide synthetase
CIW72_02805	ENOG4105DC1	bifunctional purine biosynthesis protein purh
CIW72_02810	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
CIW72_02815	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
CIW72_02820	ENOG41077RS	Phosphatase
CIW72_02850	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
CIW72_02875	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
CIW72_02895	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
CIW72_02905	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
CIW72_02910	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
CIW72_02915	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
CIW72_02920	ENOG4105VF7	tolerance protein
CIW72_02935	ENOG4105VV6	START domain-containing protein
CIW72_02950	ENOG4105E1F	short-chain dehydrogenase reductase
CIW72_02955	ENOG4108K8S	endonuclease I
CIW72_02965	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
CIW72_02970	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
CIW72_02985	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
CIW72_03010	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
CIW72_03015	ENOG4105EX9	Membrane
CIW72_03035	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
CIW72_03040	ENOG4108YYC	ycei family
CIW72_03070	ENOG4105WSE	Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity)
CIW72_03085	ENOG41065ZS	Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme- A to the apo- acyl-carrier-protein of the malonate decarboxylase to yield holo- acyl-carrier-protein (By similarity)
CIW72_03090	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
CIW72_03095	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
CIW72_03105	ENOG4105DRR	Transcriptional regulator, GntR family
CIW72_03110	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
CIW72_03145	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
CIW72_03150	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
CIW72_03195	ENOG4105PDP	Short chain dehydrogenase
CIW72_03205	ENOG4105CHF	Glutathione S-transferase
CIW72_03230	ENOG4105EYF	MMPL domain protein
CIW72_03240	ENOG4105C5Z	peptidase
CIW72_03245	ENOG4107QS8	(LipO)protein
CIW72_03255	ENOG4105BZU	Histidine kinase
CIW72_03280	ENOG4105DFI	Membrane
CIW72_03285	ENOG4105F87	Dehydratase
CIW72_03305	ENOG4105D7N	magnesium and cobalt transport protein CorA
CIW72_03315	ENOG4105E53	ec 3.2.1.28
CIW72_03365	ENOG4105C8Q	Methyl-accepting chemotaxis
CIW72_03370	ENOG4106R7G	Glycoside hydrolase family 5
CIW72_03375	ENOG4105CHH	sulfate transporter
CIW72_03380	ENOG4105BZU	Histidine kinase
CIW72_03400	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
CIW72_03410	ENOG4108HRK	Histidine kinase
CIW72_03415	ENOG4108NEV	two component transcriptional regulator, LytTR family
CIW72_03420	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
CIW72_03470	ENOG4105WD1	Membrane
CIW72_03480	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
CIW72_03490	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CIW72_03495	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
CIW72_03500	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
CIW72_03525	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CIW72_03530	ENOG41064RH	membrane protein YliF
CIW72_03535	ENOG4105CD8	aminopeptidase N
CIW72_03555	ENOG4105DZG	Dehydrogenase
CIW72_03560	ENOG4108Q1J	Extracellular solute-binding protein, family 3
CIW72_03585	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
CIW72_03595	ENOG4105DFF	Rod shape-determining protein mreb
CIW72_03600	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
CIW72_03615	ENOG4105CNI	cell division protein FtsW
CIW72_03625	ENOG4105CVE	Lytic murein transglycosylase
CIW72_03630	ENOG4105K6T	rare lipoprotein A
CIW72_03640	ENOG4105DZ1	carboxypeptidase
CIW72_03655	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
CIW72_03660	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
CIW72_03665	ENOG4105CN1	protease
CIW72_03675	ENOG4105EGI	Transcriptional regulator
CIW72_03720	ENOG4108J5G	6-phosphogluconate dehydrogenase
CIW72_03725	ENOG4105D9R	oxidoreductase
CIW72_03730	ENOG4105W4M	Transport-associated protein
CIW72_03735	ENOG4105BZU	Histidine kinase
CIW72_03745	ENOG4105BZU	Histidine kinase
CIW72_03755	ENOG4105CHR	reductase
CIW72_03800	ENOG4105GVR	general secretion pathway protein D
CIW72_03805	ENOG4107QHF	type ii secretion system protein e
CIW72_03810	ENOG4105D7Q	type ii secretion system
CIW72_03815	ENOG4108VAU	general secretion pathway protein G
CIW72_03820	ENOG4105VWV	general secretion pathway protein h
CIW72_03825	ENOG4105X5Z	General secretion pathway protein I
CIW72_03835	ENOG4108RTD	type II secretion system protein K
CIW72_03860	ENOG4105CNT	hydrolase family 2
CIW72_03875	ENOG4105FDP	GntR family transcriptional regulator
CIW72_03885	ENOG4105ETE	Transcriptional regulator (LacI family
CIW72_03890	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
CIW72_03895	ENOG4105CE4	GlcNAc 6-P deacetylase
CIW72_03905	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CIW72_03910	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
CIW72_03915	ENOG4105C26	Dehydrogenase
CIW72_03920	ENOG4105C94	Transporter
CIW72_03935	ENOG4108Z33	Thiol disulfide Interchange Protein
CIW72_03945	ENOG4106RE7	Cytochrome
CIW72_03950	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
CIW72_03955	ENOG4105CY0	Metallo-Beta-Lactamase
CIW72_03975	ENOG4105JJR	Histidine kinase
CIW72_03980	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
CIW72_04005	ENOG4108QBQ	Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione (By similarity)
CIW72_04020	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
CIW72_04025	ENOG4105JAB	phenazine biosynthesis protein, phzf family
CIW72_04040	ENOG4105C5H	ABC transporter
CIW72_04050	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
CIW72_04055	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
CIW72_04065	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
CIW72_04080	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
CIW72_04085	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
CIW72_04090	ENOG4107YIM	Involved in the transcription termination process (By similarity)
CIW72_04095	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
CIW72_04120	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
CIW72_04125	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
CIW72_04130	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
CIW72_04135	ENOG4105C08	Histidine kinase
CIW72_04140	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
CIW72_04155	ENOG4105CQB	FAD linked oxidase domain protein
CIW72_04160	ENOG4105S2T	inner membrane protein YbcI
CIW72_04165	ENOG41082RQ	UPF0102 protein
CIW72_04200	ENOG4108V6E	Cell division protein mraZ
CIW72_04205	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
CIW72_04210	ENOG4106932	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
CIW72_04215	ENOG4105CJN	penicillin-binding protein
CIW72_04220	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
CIW72_04225	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
CIW72_04230	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
CIW72_04240	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
CIW72_04245	ENOG4105DFU	Cell wall formation (By similarity)
CIW72_04250	ENOG4105CPF	Cell wall formation (By similarity)
CIW72_04255	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
CIW72_04260	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
CIW72_04265	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
CIW72_04270	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CIW72_04280	ENOG4105DR5	peptidase
CIW72_04285	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
CIW72_04290	ENOG4105M6F	mutator MutT protein
CIW72_04300	ENOG4105SYT	Methylenetetrahydrofolate reductase
CIW72_04370	ENOG4105DXX	methyltransferase
CIW72_04375	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
CIW72_04385	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
CIW72_04420	ENOG4105D6F	Phosphatase
CIW72_04425	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
CIW72_04435	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
CIW72_04440	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
CIW72_04450	ENOG4108RVA	ribokinase
CIW72_04455	ENOG4105D9N	nucleoside
CIW72_04465	ENOG4105CPC	Aldo Keto reductase
CIW72_04475	ENOG4105D05	Receptor
CIW72_04495	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
CIW72_04510	ENOG4105E2B	Taurine dioxygenase
CIW72_04520	ENOG4108I0Y	(ABC) transporter
CIW72_04525	ENOG4108UJV	acyl-CoA thioesterase i
CIW72_04530	ENOG4105ETX	regulatoR
CIW72_04535	ENOG4105DHQ	Histidine kinase
CIW72_04550	ENOG41080IJ	Diacylglycerol kinase
CIW72_04570	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
CIW72_04575	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
CIW72_04590	ENOG4107SM7	Transcriptional regulator
CIW72_04595	ENOG4107T8P	acyl-Coa dehydrogenase
CIW72_04600	ENOG4105D7T	ABC transporter
CIW72_04605	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
CIW72_04615	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
CIW72_04620	ENOG4108UZX	fmn reductase
CIW72_04645	ENOG4105DEF	Extracellular solute-binding protein, family 5
CIW72_04665	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
CIW72_04670	ENOG4105NWN	ApaG protein
CIW72_04675	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
CIW72_04680	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
CIW72_04685	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
CIW72_04690	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
CIW72_04710	ENOG4108WBT	adenosyltransferase
CIW72_04725	ENOG4105D0A	hydroxylase
CIW72_04730	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
CIW72_04770	ENOG4105DDW	LysR family Transcriptional regulator
CIW72_04775	ENOG4105CEY	Amp-dependent synthetase and ligase
CIW72_04785	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
CIW72_04845	ENOG4105DXC	membrane
CIW72_04855	ENOG4105CX6	glutaminyL-tRNA synthetase
CIW72_04870	ENOG4105BZU	Histidine kinase
CIW72_04875	ENOG4105BZU	Histidine kinase
CIW72_04880	ENOG4105WH1	Two component transcriptional regulator luxr family
CIW72_04890	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
CIW72_04900	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
CIW72_04905	ENOG4105NXH	GreA GreB family elongation factor
CIW72_04915	ENOG4105C5Q	Transcriptional regulator
CIW72_04930	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
CIW72_04950	ENOG4105C2M	dna polymerase I
CIW72_04980	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
CIW72_05000	ENOG4105W8H	transhydrogenase (subunit alpha
CIW72_05005	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
CIW72_05020	ENOG4105CM2	brancheD-chain amino acid aminotransferase
CIW72_05035	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
CIW72_05040	ENOG4108Z66	YbaK ebsC protein
CIW72_05060	ENOG4105CS1	NAD(P)H quinone oxidoreductase
CIW72_05065	ENOG4107S2Z	UPF0761 membrane protein
CIW72_05070	ENOG4107QX9	Thiol disulfide interChange protein
CIW72_05085	ENOG4105CSR	polyphosphate kinase 2
CIW72_05090	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
CIW72_05100	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
CIW72_05105	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
CIW72_05110	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
CIW72_05115	ENOG4105QVB	outer membrane lipoprotein LolB
CIW72_05120	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
CIW72_05130	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
CIW72_05135	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
CIW72_05140	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
CIW72_05145	ENOG4105C3G	gtp-binding protein
CIW72_05165	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
CIW72_05175	ENOG4105PM1	preprotein translocase subunit SecE
CIW72_05180	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
CIW72_05185	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
CIW72_05190	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
CIW72_05195	ENOG4108VZM	50s ribosomal protein L10
CIW72_05200	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
CIW72_05205	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CIW72_05210	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CIW72_05215	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
CIW72_05220	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
CIW72_05225	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
CIW72_05230	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
CIW72_05235	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
CIW72_05240	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
CIW72_05245	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
CIW72_05250	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
CIW72_05255	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CIW72_05260	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
CIW72_05265	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
CIW72_05270	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
CIW72_05275	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
CIW72_05285	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
CIW72_05290	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
CIW72_05295	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
CIW72_05300	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CIW72_05305	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
CIW72_05310	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
CIW72_05315	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
CIW72_05320	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
CIW72_05325	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
CIW72_05335	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
CIW72_05340	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
CIW72_05345	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CIW72_05350	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
CIW72_05355	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
CIW72_05360	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CIW72_05365	ENOG4108ZT0	50S ribosomal protein l17
CIW72_05370	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
CIW72_05390	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
CIW72_05400	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
CIW72_05415	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
CIW72_05420	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
CIW72_05455	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
CIW72_05460	ENOG4105CIS	alcohol dehydrogenase
CIW72_05470	ENOG4105CDV	Ompa motb domain protein
CIW72_05480	ENOG4108R99	pseudouridine synthase
CIW72_05490	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
CIW72_05495	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
CIW72_05500	ENOG4108I5D	sulfate abc transporter
CIW72_05510	ENOG4108IJ6	ABC transporter
CIW72_05520	ENOG4105CPQ	Dehydrogenase
CIW72_05535	ENOG4105HSS	phospholipase C
CIW72_05550	ENOG4105CVJ	phosphoglycerate mutase
CIW72_05555	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
CIW72_05570	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
CIW72_05575	ENOG4105ED9	Protein of unknown function (DUF455)
CIW72_05585	ENOG4108YP4	Metalloprotease, specifically cleaves on the N-terminal side of aspartyl, glutamyl and cysteic acid residues (By similarity)
CIW72_05595	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
CIW72_05600	ENOG4105EYK	Phosphatidylglycerophosphatase B
CIW72_05605	ENOG4105BZF	Glycosyl transferase (Group 1
CIW72_05610	ENOG4105C9X	ppx gppa phosphatase
CIW72_05615	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
CIW72_05620	ENOG4105BZU	Histidine kinase
CIW72_05625	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CIW72_05630	ENOG4105ERG	peptidase m48, ste24p
CIW72_05635	ENOG4105VW4	glutaredoxin 3
CIW72_05645	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
CIW72_05715	ENOG4105NVB	glycoside hydrolase, family 19
CIW72_05775	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
CIW72_05785	ENOG4105ETX	regulatoR
CIW72_05790	ENOG4105BZU	Histidine kinase
CIW72_05820	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
CIW72_05825	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
CIW72_05865	ENOG4107QHF	type ii secretion system protein e
CIW72_05870	ENOG4107QHF	type ii secretion system protein e
CIW72_05875	ENOG4107QHF	type ii secretion system protein e
CIW72_05880	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CIW72_05885	ENOG4107TUY	Histidine kinase
CIW72_05890	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
CIW72_05895	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
CIW72_05910	ENOG4105C4K	Nad synthetase
CIW72_05920	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CIW72_05925	ENOG4105C34	Pseudouridine synthase
CIW72_05940	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
CIW72_05945	ENOG4105C8Q	Methyl-accepting chemotaxis
CIW72_05955	ENOG4105DZG	Dehydrogenase
CIW72_05960	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
CIW72_05965	ENOG4105BZP	glycoside hydrolase 15-related
CIW72_05970	ENOG4108K4C	ec 3.1.3.12
CIW72_05975	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
CIW72_06010	ENOG41082IR	Excinuclease ABC C subunit domain protein
CIW72_06015	ENOG4107ZSV	Receptor
CIW72_06020	ENOG4105CPU	Monooxygenase
CIW72_06040	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
CIW72_06045	ENOG4105E2Y	ABC, transporter
CIW72_06050	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CIW72_06055	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
CIW72_06070	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
CIW72_06075	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
CIW72_06080	ENOG4105EFT	decarboxylase
CIW72_06085	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
CIW72_06090	ENOG4108YZT	Adenosylcobinamide kinase
CIW72_06095	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
CIW72_06115	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
CIW72_06125	ENOG4105C6X	Major Facilitator
CIW72_06140	ENOG4105GAV	receptor
CIW72_06165	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
CIW72_06180	ENOG4107RNH	Outer membrane receptor FepA
CIW72_06185	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
CIW72_06200	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
CIW72_06205	ENOG4105C5H	ABC transporter
CIW72_06215	ENOG4105ETT	transcriptional Regulator, LysR family
CIW72_06235	ENOG4105HSS	phospholipase C
CIW72_06250	ENOG4108ISG	Major Facilitator
CIW72_06265	ENOG4105C9M	aspartyl-trna synthetase
CIW72_06280	ENOG4105CDY	transcriptional regulatory protein
CIW72_06285	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
CIW72_06290	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
CIW72_06295	ENOG4105DFH	Transport of potassium into the cell (By similarity)
CIW72_06305	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
CIW72_06310	ENOG4107YD3	Thioesterase
CIW72_06315	ENOG4105E02	MotA TolQ exbB proton channel
CIW72_06330	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
CIW72_06335	ENOG4105KCK	Peptidoglycan-associated lipoprotein
CIW72_06345	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
CIW72_06355	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
CIW72_06360	ENOG410903D	sensor protein
CIW72_06380	ENOG4105C8Q	Methyl-accepting chemotaxis
CIW72_06415	ENOG4105C9U	ATP-dependent DNA helicase RecQ
CIW72_06430	ENOG4105CQ7	ATP-dependent helicase
CIW72_06445	ENOG4105CHC	glucokinase (EC 2.7.1.2)
CIW72_06460	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
CIW72_06465	ENOG4105Z85	coenzyme PQQ synthesis
CIW72_06470	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
CIW72_06475	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
CIW72_06480	ENOG410698T	Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide (By similarity)
CIW72_06485	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
CIW72_06505	ENOG4105BZ4	penicillin-binding protein
CIW72_06515	ENOG4105DVT	helicase
CIW72_06520	ENOG41072GX	Peptidase M22 Glycoprotease
CIW72_06525	ENOG41065RQ	ADP-ribosylation crystallin J1
CIW72_06535	ENOG4105D7Z	glutathione synthase
CIW72_06540	ENOG4108UNF	response regulator
CIW72_06545	ENOG4105M3Z	response regulator
CIW72_06550	ENOG410807Z	Modulation of CheA activity in response to attractants (Chemotaxis
CIW72_06555	ENOG4105C8Q	Methyl-accepting chemotaxis
CIW72_06560	ENOG4105CBS	Chea signal transduction histidine kinase
CIW72_06575	ENOG4105D9U	N-acetyltransferase
CIW72_06600	ENOG4106N3A	copper homeostasis protein cutc
CIW72_06640	ENOG4105CWX	Alpha-1,2-mannosidase
CIW72_06685	ENOG4105VRS	hydrolase family 18
CIW72_06700	ENOG4105CHC	glucokinase (EC 2.7.1.2)
CIW72_06705	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
CIW72_06715	ENOG4107RK2	ADP-ribose diphosphatase NudE
CIW72_06720	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
CIW72_06725	ENOG4105DXN	mazG family
CIW72_06730	ENOG4105KK4	UPF0060 membrane protein
CIW72_06745	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
CIW72_06750	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
CIW72_06775	ENOG4107QPN	acyl-Coa dehydrogenase
CIW72_06785	ENOG4108IG5	Transcriptional regulator
CIW72_06805	ENOG4105D05	Receptor
CIW72_06815	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
CIW72_06820	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
CIW72_06830	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
CIW72_06835	ENOG41066T0	asmA family
CIW72_06840	ENOG4108UT2	hemolysin iii
CIW72_06845	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
CIW72_06850	ENOG4105DR5	peptidase
CIW72_06855	ENOG4106TYC	homoserine o-acetyltransferase (EC 2.3.1.31)
CIW72_06860	ENOG4105C28	cystathionine
CIW72_06865	ENOG4105CFH	Aspartokinase
CIW72_06880	ENOG4105EJQ	L-serine dehydratase
CIW72_06900	ENOG4108YYC	ycei family
CIW72_06905	ENOG4105BZU	Histidine kinase
CIW72_06915	ENOG4105BZU	Histidine kinase
CIW72_06920	ENOG4105BZU	Histidine kinase
CIW72_06925	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
CIW72_06930	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
CIW72_06940	ENOG4105D49	3-dehydroquinate synthase
CIW72_06945	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
CIW72_06950	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
CIW72_06960	ENOG4108P9J	Phage shock protein A
CIW72_06985	ENOG4106032	Glutathionylspermidine synthase
CIW72_07000	ENOG4108Z4X	TRANSCRIPTIONal
CIW72_07030	ENOG4105QV4	Tryptophan halogenase
CIW72_07050	ENOG4108MHS	Lysyl endopeptidase
CIW72_07075	ENOG4105CUB	amino acid
CIW72_07100	ENOG4108NFF	pectate lyase
CIW72_07110	ENOG4105C85	amino acid
CIW72_07120	ENOG4105C4M	(Ubiquinol oxidase) subunit I
CIW72_07125	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
CIW72_07135	ENOG4107UWA	esterase
CIW72_07140	ENOG4105CJW	magnesium transporter
CIW72_07150	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
CIW72_07155	ENOG41080Z8	PHOSPHOCARRIER protein
CIW72_07165	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
CIW72_07170	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
CIW72_07175	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
CIW72_07180	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
CIW72_07185	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CIW72_07190	ENOG4108IUZ	ABC transporter
CIW72_07195	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
CIW72_07205	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
CIW72_07210	ENOG4105C2X	Arabinose 5-phosphate isomerase
CIW72_07220	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
CIW72_07240	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
CIW72_07255	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
CIW72_07265	ENOG4105C02	permease
CIW72_07275	ENOG4108S0S	Nucleotidyl transferase
CIW72_07280	ENOG4105EHM	Aminoglycoside phosphotransferase
CIW72_07295	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
CIW72_07310	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
CIW72_07315	ENOG4105CJ2	(LipO)protein
CIW72_07340	ENOG4107E2E	PKHD-type hydroxylase
CIW72_07345	ENOG4108IU3	tonb-dependent siderophore receptor
CIW72_07360	ENOG4105C9B	Cysteine desulfurase
CIW72_07365	ENOG4105JRK	feS assembly protein SufD
CIW72_07370	ENOG4105C3K	feS assembly ATPase SufC
CIW72_07390	ENOG4108Z0Z	intracellular protease Pfpi family
CIW72_07410	ENOG4105FAA	peptidase M23
CIW72_07420	ENOG4105II7	pyrroline-5-carboxylate reductase
CIW72_07425	ENOG4105DFA	alanine racemase domain protein
CIW72_07430	ENOG4105CZX	twitching motility protein
CIW72_07435	ENOG4105CZX	twitching motility protein
CIW72_07460	ENOG4108UJU	UPF0301 protein
CIW72_07465	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
CIW72_07470	ENOG4105CXT	aspartate transcarbamylase
CIW72_07475	ENOG4108Z9K	Osmotically inducible protein
CIW72_07485	ENOG4105JAB	phenazine biosynthesis protein, phzf family
CIW72_07490	ENOG4105JAB	phenazine biosynthesis protein, phzf family
CIW72_07495	ENOG4105CFH	Aspartokinase
CIW72_07510	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
CIW72_07525	ENOG4105EAH	synthase
CIW72_07530	ENOG4108UUM	single-stranded DNA-binding protein
CIW72_07545	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
CIW72_07550	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
CIW72_07555	ENOG4105C7W	Xanthine dehydrogenase
CIW72_07560	ENOG4107XAN	XdhC and CoxI family
CIW72_07605	ENOG4105VCD	cytoplasmic protein
CIW72_07610	ENOG4105D22	carbon starvation protein
CIW72_07615	ENOG4105EUB	pirin domain protein
CIW72_07630	ENOG4105EUB	pirin domain protein
CIW72_07640	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
CIW72_07645	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
CIW72_07660	ENOG4107RZC	phospholipase d
CIW72_07665	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
CIW72_07670	ENOG4105BZU	Histidine kinase
CIW72_07675	ENOG4105BZU	Histidine kinase
CIW72_07680	ENOG4108V3W	Chemotaxis protein, CheW
CIW72_07685	ENOG4105C8Q	Methyl-accepting chemotaxis
CIW72_07690	ENOG4105CBS	Chea signal transduction histidine kinase
CIW72_07735	ENOG4108JA2	transcriptioN-repair coupling factor
CIW72_07745	ENOG4105D6S	protein involved in catabolism of external DNA
CIW72_07750	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
CIW72_07755	ENOG4105EB3	Histidine kinase
CIW72_07765	ENOG4105CT7	inner membrane cred family protein
CIW72_07790	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
CIW72_07795	ENOG4105MYN	Zinc uptake regulation protein
CIW72_07805	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
CIW72_07810	ENOG4105BZS	acriflavin resistance protein
CIW72_07815	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
CIW72_07820	ENOG4108JGH	Tetr family transcriptional regulator
CIW72_07825	ENOG4107SET	aldo keto reductase
CIW72_07830	ENOG4105EQ2	LysR family Transcriptional regulator
CIW72_07840	ENOG4105CF7	AraC family transcriptional regulator
CIW72_07850	ENOG4105CC0	LysR family Transcriptional regulator
CIW72_07855	ENOG4105F27	Major Facilitator
CIW72_07890	ENOG4105UGU	tonB-dependent Receptor
CIW72_07915	ENOG4105CMQ	Chloride channel
CIW72_07980	ENOG4105BZU	Histidine kinase
CIW72_07985	ENOG4105FE9	pseudouridine synthase
CIW72_07990	ENOG4105BZU	Histidine kinase
CIW72_08010	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
CIW72_08030	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CIW72_08035	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
CIW72_08065	ENOG4105BZ1	(ABC) transporter
CIW72_08105	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
CIW72_08110	ENOG4105WG9	Conserved Protein
CIW72_08135	ENOG4107QR8	Thioredoxin
CIW72_08145	ENOG4105C8T	Leucyl-tRNA synthetase
CIW72_08160	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
CIW72_08175	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
CIW72_08190	ENOG4105MPN	Membrane
CIW72_08195	ENOG4108Z03	MAF-like protein
CIW72_08200	ENOG4105C03	ribonuclease
CIW72_08205	ENOG4105QD6	exported protein
CIW72_08215	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
CIW72_08220	ENOG4105N42	UPF0307 protein
CIW72_08225	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
CIW72_08240	ENOG4105CTB	Polyprenyl synthetase
CIW72_08245	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
CIW72_08250	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
CIW72_08260	ENOG4105G6Z	alkaline phosphatase
CIW72_08265	ENOG4105CK2	sodium dicarboxylate symporter
CIW72_08270	ENOG41082K6	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
CIW72_08280	ENOG4105K4H	Nlp p60 protein
CIW72_08285	ENOG4105K4H	Nlp p60 protein
CIW72_08290	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
CIW72_08300	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
CIW72_08305	ENOG4105DC8	reductase
CIW72_08325	ENOG4105C9K	Endothelin-converting enzyme 1
CIW72_08335	ENOG4105C9K	Endothelin-converting enzyme 1
CIW72_08365	ENOG4105DHP	deoxycytidine triphosphate deaminase
CIW72_08410	ENOG4108RRZ	Transcription elongation factor GreB
CIW72_08430	ENOG4107VIJ	nudix hydrolase
CIW72_08435	ENOG4105D7A	ATP-binding protein
CIW72_08450	ENOG4105DJ4	phosphatidylserine decarboxylase
CIW72_08460	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
CIW72_08465	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
CIW72_08470	ENOG4105C5I	Dehydrogenase
CIW72_08475	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
CIW72_08495	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
CIW72_08500	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
CIW72_08510	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
CIW72_08520	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
CIW72_08525	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
CIW72_08530	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
CIW72_08545	ENOG4105BZU	Histidine kinase
CIW72_08560	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
CIW72_08565	ENOG4105CP7	Triose-phosphate isomerase
CIW72_08580	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CIW72_08585	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CIW72_08590	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CIW72_08595	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CIW72_08600	ENOG4105GKE	subunit e
CIW72_08605	ENOG4107QIZ	NADH dehydrogenase
CIW72_08610	ENOG4107R0R	NADH dehydrogenase subunit g
CIW72_08615	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
CIW72_08620	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CIW72_08625	ENOG4105DF2	NADH dehydrogenase subunit j
CIW72_08635	ENOG4105D65	subunit l
CIW72_08640	ENOG4105C8S	subunit m
CIW72_08645	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CIW72_08655	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
CIW72_08660	ENOG4105CHV	Transcription elongation factor NusA
CIW72_08665	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
CIW72_08670	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
CIW72_08675	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
CIW72_08680	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
CIW72_08685	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
CIW72_08695	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
CIW72_08705	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
CIW72_08710	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
CIW72_08715	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
CIW72_08720	ENOG4105M2J	Glutaredoxin
CIW72_08730	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
CIW72_08740	ENOG4108KPZ	tonB-dependent Receptor
CIW72_08745	ENOG4105EWT	decarboxylase family
CIW72_08790	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
CIW72_08830	ENOG4105CMA	conjugation trbi family protein
CIW72_08850	ENOG4106E4H	Type IV secretory pathway VirB3 family protein
CIW72_08895	ENOG4105CG3	alpha amylase, catalytic region
CIW72_08920	ENOG4107RBJ	symporter
CIW72_08930	ENOG4105ETE	Transcriptional regulator (LacI family
CIW72_08935	ENOG4105C22	threonyL-tRNA synthetase
CIW72_08940	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
CIW72_08945	ENOG41082NX	50s ribosomal protein l35
CIW72_08950	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
CIW72_08955	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
CIW72_08960	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
CIW72_08965	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
CIW72_08970	ENOG4105WJX	transcriptional regulator MERR family
CIW72_08990	ENOG4105D3Q	Sugar transferase
CIW72_09015	ENOG4107Y2G	Glycosyl transferase (Group 1
CIW72_09025	ENOG4108NQK	Catalyzes the transfer of a glucuronic acid (GlcA) residue from UDP-glucuronate to mannose-alpha-1,3-glucose-beta- 1,4-glucose-P-P-polyisoprenyl to form the lipid-linked tetrasaccharide GlcA-Man-Glc(2)-PP-Pol, with a glucuronic acid- beta-mannose linkage. Is involved in the biosynthesis of the exopolysaccharide xanthan, since it catalyzes the fourth glycosylation step in the assembly of the pentasaccharide-P-P- polyisoprenyl repeating unit of xanthan. Is unable to use the trisaccharide acceptor freed from the pyrophosphate lipid moiety. Does not show specificity for the lipidic portion of the acceptor. Shows diminished activity when tested with 6-O-acetyl-mannose- alpha-1,3-glucose-beta-1,4-glucose-P-P-polyisoprenyl, a
CIW72_09050	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
CIW72_09055	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
CIW72_09060	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
CIW72_09080	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
CIW72_09090	ENOG4105CSU	acyl-Coa dehydrogenase
CIW72_09105	ENOG4105QNF	Outer membrane lipoprotein
CIW72_09120	ENOG4105DKD	Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity)
CIW72_09140	ENOG4105CQZ	Histidine kinase
CIW72_09145	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
CIW72_09150	ENOG4105CEN	a g-specific adenine glycosylase
CIW72_09160	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CIW72_09170	ENOG4105CTU	Proline racemase
CIW72_09175	ENOG41080HI	glycine oxidase
CIW72_09190	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
CIW72_09200	ENOG4105DC7	peptidase M24
CIW72_09215	ENOG4107QTZ	amino acid
CIW72_09280	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
CIW72_09310	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
CIW72_09315	ENOG4106H78	methyltransferase
CIW72_09320	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
CIW72_09335	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
CIW72_09340	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
CIW72_09345	ENOG4105E08	Glycoside hydrolase, family 9
CIW72_09350	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
CIW72_09390	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
CIW72_09395	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
CIW72_09400	ENOG4105VIE	preprotein translocase, subunit YajC
CIW72_09405	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CIW72_09410	ENOG4107QT7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CIW72_09435	ENOG4105DM4	PTS System
CIW72_09440	ENOG4105DE4	1-phosphofructokinase
CIW72_09445	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
CIW72_09450	ENOG4108M60	Transcriptional regulator
CIW72_09455	ENOG4105BZS	acriflavin resistance protein
CIW72_09460	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
CIW72_09470	ENOG4105C7I	Dehydrogenase
CIW72_09490	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CIW72_09495	ENOG4105BZU	Histidine kinase
CIW72_09500	ENOG4106BRA	Membrane
CIW72_09525	ENOG4105FCD	Major Facilitator
CIW72_09530	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
CIW72_09535	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
CIW72_09545	ENOG4105CSH	Transporter
CIW72_09550	ENOG4105W3S	hemerythrin-like, metal-binding protein
CIW72_09555	ENOG4105BZU	Histidine kinase
CIW72_09565	ENOG4105CFQ	glutamine synthetase
CIW72_09580	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
CIW72_09585	ENOG4107RUE	extracellular solute-binding protein family 1
CIW72_09605	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CIW72_09610	ENOG4105F38	ABC transporter, permease
CIW72_09615	ENOG4105D38	putrescine abc transporter
CIW72_09635	ENOG4108JU5	Magnesium and cobalt efflux protein
CIW72_09645	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
CIW72_09655	ENOG4105C9A	Phoh family
CIW72_09660	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
CIW72_09675	ENOG4105E4C	Lytic transglycosylase catalytic
CIW72_09685	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
CIW72_09690	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
CIW72_09695	ENOG4105EIX	cytochrome c1
CIW72_09700	ENOG4107MKT	Stringent starvation protein a
CIW72_09705	ENOG4105KB2	stringent starvation protein b
CIW72_09725	ENOG4107QRT	dEAD DEAH box helicase
CIW72_09730	ENOG4108VX5	3-methyladenine DNA glycosylase
CIW72_09735	ENOG4105C8Q	Methyl-accepting chemotaxis
CIW72_09775	ENOG4105DQE	DNA ligase
CIW72_09795	ENOG4105E6M	Sulphatase-modifying factor protein
CIW72_09805	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
CIW72_09810	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
CIW72_09815	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
CIW72_09820	ENOG4105K8N	protein family UPF0079, ATPase
CIW72_09825	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
CIW72_09830	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
CIW72_09855	ENOG4105CHR	reductase
CIW72_09860	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
CIW72_09865	ENOG4105D0M	Protease HtpX homolog
CIW72_09875	ENOG4105CBX	hi0933 family
CIW72_09880	ENOG4108VWS	Yaeq family
CIW72_09885	ENOG4105VEQ	Cold shock protein
CIW72_09890	ENOG4108RXX	maleylacetoacetate isomerase
CIW72_09900	ENOG4105CNG	UPF0061 protein
CIW72_09905	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
CIW72_09910	ENOG4105C1J	atp-dependent rna helicase
CIW72_09915	ENOG4105C5H	ABC transporter
CIW72_09935	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
CIW72_09940	ENOG4105ECY	inositol monophosphatase
CIW72_09955	ENOG4105BZU	Histidine kinase
CIW72_09960	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
CIW72_09965	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
CIW72_09975	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
CIW72_09980	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
CIW72_09985	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
CIW72_10045	ENOG4107FQ9	ethanolamine ammonia-lyase
CIW72_10050	ENOG4105CPD	ethanolamine ammonia-lyase
CIW72_10075	ENOG4105CD3	dihydroorotase
CIW72_10080	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
CIW72_10085	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CIW72_10095	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
CIW72_10100	ENOG4105C8N	cysteinyl-tRNA synthetase
CIW72_10110	ENOG4105DBV	ornithine carbamoyltransferase
CIW72_10115	ENOG4105CDH	Citrulline--aspartate ligase
CIW72_10130	ENOG4105CAS	nag kinase
CIW72_10140	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
CIW72_10145	ENOG4105CH7	arginosuccinase
CIW72_10155	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
CIW72_10160	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
CIW72_10190	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
CIW72_10195	ENOG4105C4M	(Ubiquinol oxidase) subunit I
CIW72_10200	ENOG4108JJ9	ABC, transporter
CIW72_10205	ENOG4108JJ8	(ABC) transporter
CIW72_10220	ENOG4108M1T	Cytochrome c-type biogenesis protein
CIW72_10225	ENOG4105KWW	Biogenesis protein
CIW72_10235	ENOG4105DA4	cytochrome c-type biogenesis protein
CIW72_10240	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
CIW72_10250	ENOG41060IM	Heme exporter protein
CIW72_10255	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
CIW72_10260	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
CIW72_10265	ENOG4105CHM	Aminotransferase
CIW72_10285	ENOG4105FE9	pseudouridine synthase
CIW72_10290	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
CIW72_10295	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
CIW72_10300	ENOG4105K9H	YciI-like protein
CIW72_10330	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
CIW72_10335	ENOG4105DRS	transport system, permease
CIW72_10365	ENOG4105DWY	Agmatine deiminase
CIW72_10380	ENOG4105YK5	50S ribosomal protein L36
CIW72_10385	ENOG4105CAT	Cytidine monophosphate kinase
CIW72_10390	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
CIW72_10395	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
CIW72_10405	ENOG4105CFV	Tetratricopeptide repeat protein
CIW72_10410	ENOG4105ESV	Glycosyl transferase, family 4
CIW72_10420	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
CIW72_10425	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
CIW72_10435	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
CIW72_10440	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
CIW72_10445	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
CIW72_10450	ENOG4105DFP	Integrase
CIW72_10490	ENOG4107S5I	aldo keto reductase
CIW72_10500	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
CIW72_10560	ENOG4105EVH	UPF0753 protein
CIW72_10570	ENOG4105DND	Transcriptional regulator
CIW72_10590	ENOG4105WH1	Two component transcriptional regulator luxr family
CIW72_10605	ENOG4105CHJ	isochorismatase hydrolase
CIW72_10620	ENOG4107SFI	Major Facilitator superfamily
CIW72_10630	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
CIW72_10635	ENOG4105KST	dependent repressor
CIW72_10640	ENOG4108Z6B	deaminase
CIW72_10645	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
CIW72_10660	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
CIW72_10680	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
CIW72_10690	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
CIW72_10715	ENOG4105BZM	domain protein
CIW72_10725	ENOG4105BZU	Histidine kinase
CIW72_10770	ENOG4105N7H	Cytochrome
CIW72_10820	ENOG4108UHU	Aldolase
CIW72_10825	ENOG4105C01	Dihydroxy-acid dehydratase
CIW72_10830	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
CIW72_10835	ENOG4105CHC	glucokinase (EC 2.7.1.2)
CIW72_10850	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
CIW72_10860	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
CIW72_10885	ENOG410681N	tpr repeat protein
CIW72_10895	ENOG4105D60	lipoprotein releasing system transmembrane protein
CIW72_10900	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CIW72_10910	ENOG4108EC8	DNA internalization-related competence protein ComEC
CIW72_10925	ENOG4105BZ1	(ABC) transporter
CIW72_10930	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
CIW72_10935	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
CIW72_10940	ENOG4105KJF	protein tyrosine phosphatase
CIW72_10950	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
CIW72_10955	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
CIW72_10990	ENOG4105CBS	Chea signal transduction histidine kinase
CIW72_11000	ENOG4108VYJ	response regulator receiver protein
CIW72_11005	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CIW72_11010	ENOG4107R21	site-determining protein
CIW72_11015	ENOG4105FZW	flagellar biosynthesis regulator FlhF
CIW72_11020	ENOG4105D7B	Flagellar biosynthesis protein flha
CIW72_11025	ENOG4105D00	flagellar biosynthetic protein flhB
CIW72_11030	ENOG4105BZU	Histidine kinase
CIW72_11035	ENOG4105BZU	Histidine kinase
CIW72_11050	ENOG4106RHG	Yeca family
CIW72_11070	ENOG4108C33	Resolvase
CIW72_11080	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
CIW72_11085	ENOG4105VS8	Flagellar biosynthetic protein fliq
CIW72_11090	ENOG4105CN7	Flagellar biosynthetic protein FliP
CIW72_11095	ENOG4105K0P	flagellar biosynthesis protein
CIW72_11100	ENOG4105DD5	Flagellar motor switch protein
CIW72_11105	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
CIW72_11125	ENOG4108JIR	Flagellum-specific ATP synthase
CIW72_11135	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
CIW72_11140	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
CIW72_11145	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
CIW72_11155	ENOG4107RGC	Glycosyl transferase, family 2
CIW72_11160	ENOG4105C74	pyruvyl transferase
CIW72_11190	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
CIW72_11195	ENOG4108P1X	synthase
CIW72_11210	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CIW72_11215	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
CIW72_11220	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CIW72_11240	ENOG4105MQ3	flagellar protein FliS
CIW72_11245	ENOG4107W9T	flagellar hook-associated
CIW72_11255	ENOG4105DTJ	flagellar hook-associated protein
CIW72_11265	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
CIW72_11270	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
CIW72_11275	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
CIW72_11280	ENOG4105CGA	flagellar basal-body rod protein FlgG
CIW72_11295	ENOG4108KPB	Flagellar basal-body rod protein FlgF
CIW72_11300	ENOG4105BZE	flagellar hook protein, FlgE
CIW72_11305	ENOG410822I	Flagellar hook capping protein
CIW72_11310	ENOG4108ZC9	flagellar basal-body rod protein flgc
CIW72_11320	ENOG4107R88	Chemotaxis protein (CheV)
CIW72_11340	ENOG4105BZU	Histidine kinase
CIW72_11345	ENOG4105BZU	Histidine kinase
CIW72_11355	ENOG4105BZU	Histidine kinase
CIW72_11375	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
CIW72_11385	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
CIW72_11390	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CIW72_11395	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
CIW72_11400	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
CIW72_11410	ENOG4105C3M	thioredoxin reductase
CIW72_11415	ENOG4105CNU	cell division protein FtsK
CIW72_11425	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
CIW72_11435	ENOG4105D1H	recombination factor protein RarA
CIW72_11440	ENOG41082MI	Protein CrcB homolog
CIW72_11450	ENOG4105CHU	acetyl-coa acetyltransferase
CIW72_11465	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
CIW72_11470	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
CIW72_11480	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
CIW72_11490	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
CIW72_11495	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
CIW72_11500	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
CIW72_11505	ENOG4105D06	uba thif-type nad fad binding protein
CIW72_11660	ENOG4105CGK	Exodeoxyribonuclease III
CIW72_11670	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
CIW72_11675	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
CIW72_11685	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
CIW72_11710	ENOG4108N8X	transition metal ion binding
CIW72_11740	ENOG4108ZXC	Two component transcriptional regulator, luxr family
CIW72_11760	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
CIW72_11785	ENOG4105DY9	regulatoR
CIW72_11820	ENOG4105W39	Membrane
CIW72_12075	ENOG4105RJZ	Transcriptional regulator
CIW72_12085	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
CIW72_12090	ENOG41090A4	Pterin carbinolamine dehydratase
CIW72_12100	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
CIW72_12110	ENOG4105EI2	Pseudouridine synthase
CIW72_12115	ENOG4105C03	ribonuclease
CIW72_12125	ENOG4105C72	UPF0176 protein
CIW72_12135	ENOG4108V1T	peptidylprolyl cis-trans isomerase
CIW72_12145	ENOG4107QQG	Dehydrogenase
CIW72_12215	ENOG4105E14	MotA TolQ exbB proton channel
CIW72_12220	ENOG4105ER2	Ompa motb domain protein
CIW72_12225	ENOG4107QJE	Chromosome Partitioning Protein
CIW72_12230	ENOG4108V3W	Chemotaxis protein, CheW
CIW72_12240	ENOG4108VYJ	response regulator receiver protein
CIW72_12245	ENOG4105CBS	Chea signal transduction histidine kinase
CIW72_12250	ENOG4105C8Q	Methyl-accepting chemotaxis
CIW72_12260	ENOG4105C8Q	Methyl-accepting chemotaxis
CIW72_12265	ENOG4105C8Q	Methyl-accepting chemotaxis
CIW72_12280	ENOG4105C8Q	Methyl-accepting chemotaxis
CIW72_12290	ENOG4105C8Q	Methyl-accepting chemotaxis
CIW72_12305	ENOG4105C8Q	Methyl-accepting chemotaxis
CIW72_12310	ENOG4105C8Q	Methyl-accepting chemotaxis
CIW72_12315	ENOG4105C8Q	Methyl-accepting chemotaxis
CIW72_12340	ENOG4108V3W	Chemotaxis protein, CheW
CIW72_12350	ENOG4105C8Q	Methyl-accepting chemotaxis
CIW72_12355	ENOG4105BZU	Histidine kinase
CIW72_12360	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
CIW72_12365	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
CIW72_12370	ENOG4105BZU	Histidine kinase
CIW72_12375	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
CIW72_12380	ENOG4107QIJ	Aconitate hydratase 2
CIW72_12395	ENOG4107QM5	aconitate hydratase
CIW72_12405	ENOG4105CEY	Amp-dependent synthetase and ligase
CIW72_12410	ENOG4105E39	Enoyl-CoA hydratase
CIW72_12415	ENOG4105BZU	Histidine kinase
CIW72_12420	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CIW72_12425	ENOG4105CRK	lysyL-tRNA synthetase
CIW72_12430	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
CIW72_12435	ENOG4105DY9	regulatoR
CIW72_12495	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
CIW72_12505	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
CIW72_12510	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
CIW72_12520	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
CIW72_12525	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
CIW72_12530	ENOG4108RPX	mosc domain containing protein
CIW72_12535	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
CIW72_12550	ENOG4105CE1	Ferrous iron transport protein b
CIW72_12570	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
CIW72_12580	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
CIW72_12600	ENOG4105CQB	FAD linked oxidase domain protein
CIW72_12605	ENOG4108JQ1	Dehydrogenase
CIW72_12615	ENOG4105CUB	amino acid
CIW72_12620	ENOG4105CUB	amino acid
CIW72_12625	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
CIW72_12630	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
CIW72_12635	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
CIW72_12650	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
CIW72_12655	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
CIW72_12660	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
CIW72_12665	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
CIW72_12670	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
CIW72_12675	ENOG4105CIH	Imidazole acetol-phosphate transaminase
CIW72_12680	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
CIW72_12685	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
CIW72_12695	ENOG4105CUT	histidyl-tRNA synthetase
CIW72_12700	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
CIW72_12800	ENOG4107BJW	polysaccharide deacetylase
CIW72_12805	ENOG4105CND	Glycosyl transferase, family 2
CIW72_12955	ENOG4105C26	Dehydrogenase
CIW72_12975	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
CIW72_12980	ENOG4105D4A	Cell wall formation (By similarity)
CIW72_12985	ENOG4108SXK	Transporter Drug Metabolite Exporter family
CIW72_13010	ENOG410841Q	phosphoesterase PA-phosphatase related protein
CIW72_13015	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
CIW72_13030	ENOG4108UYB	regulatoR
CIW72_13035	ENOG4105KU2	hydrolase family 5
CIW72_13085	ENOG4107QP8	phosphohexose isomerase
CIW72_13090	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
CIW72_13095	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
CIW72_13100	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
CIW72_13105	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CIW72_13110	ENOG4105DJ0	Poly(A) Polymerase
CIW72_13120	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
CIW72_13125	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
CIW72_13150	ENOG4105C93	Xylose Isomerase
CIW72_13155	ENOG4105CMG	Carbohydrate kinase
CIW72_13205	ENOG4108RTU	Aldolase
CIW72_13210	ENOG4105CXK	mandelate racemase muconate lactonizing
CIW72_13220	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
CIW72_13225	ENOG4108Z4U	Ferredoxin
CIW72_13235	ENOG4107TUS	Dihydrodipicolinate synthase
CIW72_13250	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CIW72_13255	ENOG4108IAB	Phoh family
CIW72_13310	ENOG4105CWB	LysR family transcriptional Regulator
CIW72_13320	ENOG4107SDU	Methyl-accepting chemotaxis
CIW72_13335	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
CIW72_13340	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
CIW72_13345	ENOG4105Y3E	Modulates RecA activity (By similarity)
CIW72_13355	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
CIW72_13360	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
CIW72_13365	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
CIW72_13370	ENOG4107TH8	cina domain protein
CIW72_13375	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
CIW72_13380	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
CIW72_13385	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
CIW72_13390	ENOG4105EEI	dihydropteroate synthase
CIW72_13395	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
CIW72_13400	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
CIW72_13405	ENOG4105HBR	Rna-binding protein
CIW72_13415	ENOG4108K5P	(LipO)protein
CIW72_13420	ENOG4108UM1	dedA family
CIW72_13425	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
CIW72_13430	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
CIW72_13435	ENOG4108DG9	Smr protein MutS2
CIW72_13440	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
CIW72_13445	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
CIW72_13450	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
CIW72_13455	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
CIW72_13460	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
CIW72_13470	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
CIW72_13475	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
CIW72_13485	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CIW72_13500	ENOG4105CJ3	phosphate transporter
CIW72_13530	ENOG4105DEN	Luciferase family
CIW72_13535	ENOG41079KZ	Major Facilitator Superfamily
CIW72_13540	ENOG4105BZ1	(ABC) transporter
CIW72_13545	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CIW72_13570	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
CIW72_13605	ENOG4105EGZ	biosynthesis protein
CIW72_13705	ENOG4105EMN	RNA polymerase sigma factor
CIW72_13720	ENOG41060IM	Heme exporter protein
CIW72_13730	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
CIW72_13735	ENOG4105DA4	cytochrome c-type biogenesis protein
CIW72_13740	ENOG4107QX9	Thiol disulfide interChange protein
CIW72_13745	ENOG4105KWW	Biogenesis protein
CIW72_13765	ENOG4105BZU	Histidine kinase
CIW72_13790	ENOG4105C8Q	Methyl-accepting chemotaxis
CIW72_13805	ENOG4105CC0	LysR family Transcriptional regulator
CIW72_13810	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
CIW72_13815	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
CIW72_13830	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
CIW72_13840	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
CIW72_13845	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
CIW72_13850	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
CIW72_13890	ENOG4105CI2	imidazolone-5-propionate hydrolase
CIW72_13895	ENOG4105C84	Histidine ammonia-lyase
CIW72_13905	ENOG4105CGP	Urocanate hydratase
CIW72_13915	ENOG4105DZG	Dehydrogenase
CIW72_13920	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CIW72_13925	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
CIW72_13940	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
CIW72_13945	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
CIW72_13950	ENOG4105CIH	Imidazole acetol-phosphate transaminase
CIW72_13960	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
CIW72_13970	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
CIW72_13975	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
CIW72_13980	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
CIW72_13985	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
CIW72_13995	ENOG4105C5S	asparaginyl-tRNA synthetase
CIW72_14035	ENOG4105WH1	Two component transcriptional regulator luxr family
CIW72_14090	ENOG41077A9	carbonic anhydrase
CIW72_14095	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
CIW72_14105	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
CIW72_14110	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
CIW72_14115	ENOG4105CJB	Exodeoxyribonuclease I
CIW72_14140	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
CIW72_14145	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
CIW72_14155	ENOG4105C5H	ABC transporter
CIW72_14185	ENOG4105KHC	sulfurtransferase
CIW72_14190	ENOG4105P8F	nudix hydrolase
CIW72_14195	ENOG4108V1T	peptidylprolyl cis-trans isomerase
CIW72_14200	ENOG4105E39	Enoyl-CoA hydratase
CIW72_14210	ENOG4105CSM	endonuclease III
CIW72_14215	ENOG4105CHH	sulfate transporter
CIW72_14220	ENOG4107B2H	carbonic anhydrase
CIW72_14240	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
CIW72_14245	ENOG4105C8U	phosphate abc transporter
CIW72_14250	ENOG4105E2Z	phosphate ABC transporter (Permease
CIW72_14255	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
CIW72_14260	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
CIW72_14270	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
CIW72_14275	ENOG4105BZU	Histidine kinase
CIW72_14280	ENOG4105C2N	RNA methyltransferase TrmH family group 3
CIW72_14290	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
CIW72_14310	ENOG4105C1G	acyl-Coa dehydrogenase
CIW72_14315	ENOG4105C1G	acyl-Coa dehydrogenase
CIW72_14330	ENOG4105C1G	acyl-Coa dehydrogenase
CIW72_14340	ENOG4105C3R	Methionine synthase
CIW72_14355	ENOG4105D7K	pfkb domain protein
CIW72_14365	ENOG4105ETE	Transcriptional regulator (LacI family
CIW72_14380	ENOG41069P5	Protein slyX homolog
CIW72_14385	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
CIW72_14390	ENOG4108V1T	peptidylprolyl cis-trans isomerase
CIW72_14405	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
CIW72_14410	ENOG4105CZV	ABC transporter
CIW72_14440	ENOG4105C37	(CBS) domain
CIW72_14450	ENOG4107QTF	adenylosuccinate lyase
CIW72_14460	ENOG4105EZE	Cupin 4 family protein
CIW72_14470	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
CIW72_14475	ENOG4105C7S	Dehydrogenase
CIW72_14485	ENOG4108URH	decarboxylase
CIW72_14495	ENOG4105BZ1	(ABC) transporter
CIW72_14500	ENOG4105C5Q	Transcriptional regulator
CIW72_14530	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
CIW72_14540	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CIW72_14545	ENOG4105CFG	Acts as a chaperone (By similarity)
CIW72_14550	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CIW72_14555	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
CIW72_14560	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
CIW72_14565	ENOG41090R7	Ferric uptake
CIW72_14570	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
CIW72_14580	ENOG4108Z1B	Cyclase dehydrase
CIW72_14585	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
CIW72_14640	ENOG4106TD9	Diguanylate cyclase
CIW72_14650	ENOG4105BZU	Histidine kinase
CIW72_14685	ENOG4105CR8	Transcriptional regulator
CIW72_14690	ENOG4105CDV	Ompa motb domain protein
CIW72_14700	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
CIW72_14705	ENOG4105CDU	Replicative dna helicase
CIW72_14715	ENOG4105CAQ	asparagine synthetase
CIW72_14725	ENOG4108K3A	Glutathione S-transferase
CIW72_14735	ENOG4105C1G	acyl-Coa dehydrogenase
CIW72_14750	ENOG4105F8V	Hydrolase, tatD family
CIW72_14755	ENOG4105CUZ	uba thif-type nad fad binding protein
CIW72_14770	ENOG4105VEQ	Cold shock protein
CIW72_14780	ENOG4105HDD	phospholipase
CIW72_14795	ENOG4107GFK	fumarate
CIW72_14805	ENOG4105DP0	ferredoxin-NADP reductase
CIW72_14810	ENOG4108V06	Glutathione peroxidase
CIW72_14820	ENOG4105DGW	oligopeptidase A
CIW72_14850	ENOG4105DUX	Transporter
CIW72_14870	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
CIW72_14875	ENOG4105CW7	secretion protein, HlyD family
CIW72_14895	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CIW72_14900	ENOG4105FQ6	thiopurine methyltransferase
CIW72_14905	ENOG4108UWD	Iron-storage protein
CIW72_14920	ENOG4108ESX	Receptor
CIW72_14930	ENOG4105CAQ	asparagine synthetase
CIW72_14935	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
CIW72_14940	ENOG4105KUZ	arsenate reductase
CIW72_14950	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
CIW72_14955	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
CIW72_14990	ENOG4105CE9	30S ribosomal protein S2
CIW72_14995	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
CIW72_15000	ENOG4105BZU	Histidine kinase
CIW72_15005	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
CIW72_15010	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
CIW72_15015	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
CIW72_15020	ENOG4105KNE	Phosphatidate cytidylyltransferase
CIW72_15025	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
CIW72_15030	ENOG4105DZP	Membrane-associated zinc metalloprotease
CIW72_15045	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CIW72_15050	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
CIW72_15055	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CIW72_15060	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CIW72_15065	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CIW72_15075	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
CIW72_15090	ENOG4108YXA	Membrane
CIW72_15140	ENOG4107QK5	Homocysteine s-methyltransferase
CIW72_15145	ENOG4108IQI	permease
CIW72_15150	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
CIW72_15155	ENOG4105DA5	(ABC) transporter
CIW72_15170	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
CIW72_15180	ENOG4108R3D	Electron transport complex
CIW72_15195	ENOG4105K6V	RNA polymerase
CIW72_15220	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
CIW72_15235	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
CIW72_15240	ENOG4105M4H	endoribonuclease L-psp
CIW72_15285	ENOG4105F27	Major Facilitator
CIW72_15295	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
CIW72_15305	ENOG4108YZY	peptidylprolyl cis-trans isomerase
CIW72_15310	ENOG4105DFF	Rod shape-determining protein mreb
CIW72_15325	ENOG4105KSC	Transcriptional regulator, TraR DksA family
CIW72_15340	ENOG4108VKG	metal-dependent hydrolase
CIW72_15365	ENOG4105CHU	acetyl-coa acetyltransferase
CIW72_15385	ENOG4105BZU	Histidine kinase
CIW72_15400	ENOG4107T0X	DNA ligase
CIW72_15410	ENOG4107T0X	DNA ligase
CIW72_15415	ENOG4107QRT	dEAD DEAH box helicase
CIW72_15425	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
CIW72_15430	ENOG4105VEQ	Cold shock protein
CIW72_15435	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
CIW72_15440	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
CIW72_15445	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
CIW72_15450	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
CIW72_15460	ENOG4107ZXU	DSBA oxidoreductase
CIW72_15465	ENOG41080ZE	Adenylate cyclase
CIW72_15470	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
CIW72_15480	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
CIW72_15485	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
CIW72_15490	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
CIW72_15500	ENOG4105C3F	Signal peptidase i
CIW72_15505	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
CIW72_15510	ENOG4105C0H	protease
CIW72_15520	ENOG4105EMN	RNA polymerase sigma factor
CIW72_15525	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
CIW72_15535	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
CIW72_15540	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
CIW72_15550	ENOG4105C1G	acyl-Coa dehydrogenase
CIW72_15555	ENOG4105C26	Dehydrogenase
CIW72_15570	ENOG4106FKC	arabinogalactan endo-1,4-beta-galactosidase
CIW72_15635	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
CIW72_15645	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
CIW72_15650	ENOG4105VEJ	Heat shock protein
CIW72_15665	ENOG4107QJQ	Mate efflux family protein
CIW72_15670	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
CIW72_15675	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
CIW72_15680	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
CIW72_15685	ENOG4105K5M	30s ribosomal protein S16
CIW72_15695	ENOG4107QWG	2-Nitropropane dioxygenase
CIW72_15700	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CIW72_15705	ENOG4105CRE	cytochrome C
CIW72_15710	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
CIW72_15715	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
CIW72_15735	ENOG4105BZU	Histidine kinase
CIW72_15740	ENOG4105BZU	Histidine kinase
CIW72_15745	ENOG4107Z5C	methylesterase
CIW72_15750	ENOG4105BZU	Histidine kinase
CIW72_15755	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
CIW72_15780	ENOG4105BZU	Histidine kinase
CIW72_15790	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
CIW72_15795	ENOG4105FUA	antagonist
CIW72_15800	ENOG4107MMM	Anti-sigma-factor antagonist
CIW72_15815	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
CIW72_15830	ENOG4105KAF	membrAne
CIW72_15835	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
CIW72_15845	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
CIW72_15850	ENOG4105CCU	oxidase (Subunit III)
CIW72_15855	ENOG4105BZ9	Cytochrome C oxidase, subunit I
CIW72_15990	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
CIW72_15995	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
CIW72_16000	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
CIW72_16005	ENOG4105DTN	riboflavin biosynthesis protein ribF
CIW72_16010	ENOG4105CJR	Integral membrane protein (MviN
CIW72_16015	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
CIW72_16020	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CIW72_16025	ENOG4105K46	50S ribosomal protein l27
CIW72_16030	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
CIW72_16035	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
CIW72_16040	ENOG4108TGP	Thioesterase superfamily protein
CIW72_16055	ENOG4105C29	acyl-CoA thioesterase
CIW72_16080	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
CIW72_16090	ENOG4107SPG	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
CIW72_16140	ENOG4105WH1	Two component transcriptional regulator luxr family
CIW72_16145	ENOG4105BZU	Histidine kinase
CIW72_16160	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
CIW72_16165	ENOG4107QMS	site-determining protein
CIW72_16170	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
CIW72_16180	ENOG4105DHQ	Histidine kinase
CIW72_16185	ENOG4105ETX	regulatoR
CIW72_16200	ENOG4105DIJ	Phosphoethanolamine transferase
CIW72_16215	ENOG4105C2C	drug resistance transporter, Bcr CflA
CIW72_16220	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CIW72_16225	ENOG4105EBR	Carboxylesterase
CIW72_16230	ENOG4105CV8	reductase
CIW72_16270	ENOG4106AXJ	AraC family transcriptional regulator
CIW72_16310	ENOG4105EPD	Oligopeptide transporter, Opt family
CIW72_16330	ENOG4105C0B	DNA polymerase III (alpha subunit)
CIW72_16345	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
CIW72_16380	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
CIW72_16385	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
CIW72_16415	ENOG4105C3M	thioredoxin reductase
CIW72_16425	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
CIW72_16430	ENOG4105CWX	Alpha-1,2-mannosidase
CIW72_16440	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
CIW72_16470	ENOG4107QMH	DNA methylase
CIW72_16480	ENOG4105ESI	atpase involved in dna repair
CIW72_16485	ENOG4105C0D	helicase
CIW72_16510	ENOG4108XFH	Transcriptional regulator
CIW72_16515	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
CIW72_16525	ENOG4105CD8	aminopeptidase N
CIW72_16530	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
CIW72_16540	ENOG4105EPW	hflc protein
CIW72_16545	ENOG4107QJR	hflk protein
CIW72_16550	ENOG4105M3Z	response regulator
CIW72_16575	ENOG4108JQB	penicillin-binding protein 1C
CIW72_16605	ENOG4105C7F	AcnD-accessory protein PrpF
CIW72_16625	ENOG4108I0Z	Aconitate hydratase
CIW72_16630	ENOG4105BZN	citrate synthase
CIW72_16635	ENOG4105CR4	methylisocitrate lyase
CIW72_16640	ENOG4108JU7	Transcriptional regulator
CIW72_16660	ENOG4107QRG	dna polymerase iii
CIW72_16665	ENOG4105HHA	aminodeoxychorismate lyase
CIW72_16675	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
CIW72_16680	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
CIW72_16685	ENOG4105CHR	reductase
CIW72_16690	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
CIW72_16700	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
CIW72_16705	ENOG4105VGS	50s ribosomal protein l32
CIW72_16710	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
CIW72_16715	ENOG4108UHJ	MAF-like protein
CIW72_16725	ENOG41089I4	Inherit from COG: Glycosyl transferase, family 2
CIW72_16735	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
CIW72_16745	ENOG4105F8C	transglutaminase domain-containing protein
CIW72_16755	ENOG4105K59	histidine triad (HIT) protein
CIW72_16760	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
CIW72_16765	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
CIW72_16770	ENOG4107QMP	dna polymerase iii subunits gamma and tau
CIW72_16785	ENOG4108ZAF	Molybdopterin
CIW72_16790	ENOG4105M00	molybdopterin converting factor, subunit 1
CIW72_16795	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
CIW72_16800	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
CIW72_16805	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
CIW72_16810	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
CIW72_16815	ENOG4105DKP	glycosyl transferase, family 9
CIW72_16830	ENOG4108ZF3	Phosphatase
CIW72_16835	ENOG4107RZZ	dna polymerase iii epsilon subunit
CIW72_16840	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CIW72_16850	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
CIW72_16860	ENOG4105EIN	peptidylprolyl cis-trans isomerase
CIW72_16890	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
CIW72_16895	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
CIW72_16900	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
CIW72_16910	ENOG4105BZU	Histidine kinase
CIW72_16915	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
CIW72_16965	ENOG4108ZXE	
CIW72_17030	ENOG4105W08	virulence gene repressor rsal
CIW72_17105	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
CIW72_17115	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
CIW72_17145	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
CIW72_17155	ENOG4105ETE	Transcriptional regulator (LacI family
CIW72_17185	ENOG4105EIB	trna rrna methyltransferase
CIW72_17195	ENOG4105CD8	aminopeptidase N
CIW72_17215	ENOG4105BZS	acriflavin resistance protein
CIW72_17225	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
CIW72_17230	ENOG4105C11	sulfate adenylyltransferase), subunit 2
CIW72_17235	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
CIW72_17240	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
CIW72_17245	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
CIW72_17265	ENOG4105BZU	Histidine kinase
CIW72_17280	ENOG4107R11	Transcriptional regulator
CIW72_17285	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
CIW72_17300	ENOG4108UVJ	appr-1-p processing domain protein
CIW72_17305	ENOG4107R1Y	fructose-bisphosphate aldolase
CIW72_17315	ENOG4105CA9	Pyruvate kinase
CIW72_17325	ENOG4105BZA	Phosphoglycerate kinase
CIW72_17350	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
CIW72_17360	ENOG4105EIF	outer membrane protein W
CIW72_17365	ENOG4105EIF	outer membrane protein W
CIW72_17375	ENOG4107S76	domain protein
CIW72_17380	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
CIW72_17385	ENOG4105E0C	molybdate abc transporter
CIW72_17390	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
CIW72_17425	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
CIW72_17430	ENOG4105DR5	peptidase
CIW72_17445	ENOG4105CNM	Receptor
CIW72_17455	ENOG4105CV1	Transketolase (EC 2.2.1.1)
CIW72_17460	ENOG4105CK2	sodium dicarboxylate symporter
CIW72_17475	ENOG4107QVM	von Willebrand factor, type A
CIW72_17495	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
CIW72_17505	ENOG4105E4G	Type IV pilus
CIW72_17530	ENOG4108JQC	penicillin-binding protein 1A
CIW72_17545	ENOG4105NRA	50s ribosomal protein l31 type b
CIW72_17550	ENOG4105DU0	nucleoside hydrolase
CIW72_17555	ENOG4105CB5	ATP-dependent DNA helicase recG
CIW72_17560	ENOG4105KME	endoribonuclease L-psp
CIW72_17565	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
CIW72_17570	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
CIW72_17575	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
CIW72_17580	ENOG4105DSJ	YicC domain protein
CIW72_17585	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
CIW72_17595	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
CIW72_17600	ENOG4105CSA	Coproporphyrinogen iii oxidase
CIW72_17615	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
CIW72_17625	ENOG4107RAQ	aminopeptidase
CIW72_17640	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
CIW72_17650	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
CIW72_17660	ENOG4105E66	phosphoriboisomerase A
CIW72_17670	ENOG41063JG	Transcriptional regulator
CIW72_17675	ENOG4105VCQ	rubredoxin
CIW72_17680	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
CIW72_17695	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
CIW72_17700	ENOG41061ZR	Transcriptional regulator
CIW72_17705	ENOG41090JD	Blue (Type 1) copper domain protein
CIW72_17710	ENOG4105CIH	Imidazole acetol-phosphate transaminase
CIW72_17740	ENOG4105C8Y	Acetylornithine aminotransferase
CIW72_17745	ENOG4105EYW	Ion transport protein
CIW72_17760	ENOG410841Q	phosphoesterase PA-phosphatase related protein
CIW72_17765	ENOG4105FFC	UPF0187 protein
CIW72_17775	ENOG4105DFU	Cell wall formation (By similarity)
CIW72_17780	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
CIW72_17795	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CIW72_17805	ENOG4105F0N	pyrophosphate phospho-hydrolase
CIW72_17820	ENOG4105ECQ	AraC Family Transcriptional Regulator
CIW72_17825	ENOG4108M3R	transcriptional activator CadC
CIW72_17830	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
CIW72_17850	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
CIW72_17855	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
CIW72_17870	ENOG4105C7B	Threonine dehydratase
CIW72_17875	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
CIW72_17880	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
CIW72_17885	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CIW72_17890	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CIW72_17895	ENOG4108MP6	LysR family Transcriptional regulator
CIW72_17910	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
CIW72_17915	ENOG4105DFG	type I secretion outer membrane protein
CIW72_17920	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
CIW72_17930	ENOG4105D1S	lipid A biosynthesis
CIW72_17955	ENOG4105C6K	Malic enzyme
CIW72_17960	ENOG4105CK2	sodium dicarboxylate symporter
CIW72_17975	ENOG4105CQZ	Histidine kinase
CIW72_17980	ENOG4105CSH	Transporter
CIW72_17990	ENOG4105F04	LysR family Transcriptional regulator
CIW72_17995	ENOG4105CPC	Aldo Keto reductase
CIW72_18010	ENOG4105WH1	Two component transcriptional regulator luxr family
CIW72_18015	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
CIW72_18020	ENOG4105DHQ	Histidine kinase
CIW72_18040	ENOG4105D4T	Citrate transporter
CIW72_18045	ENOG4105CHR	reductase
CIW72_18050	ENOG4105ETE	Transcriptional regulator (LacI family
CIW72_18065	ENOG4107QW3	Sucrose phosphorylase
CIW72_18080	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
CIW72_18125	ENOG4108JJA	ABC, transporter
CIW72_18150	ENOG4105CNM	Receptor
CIW72_18175	ENOG41069H0	dihydroorotase EC 3.5.2.3
CIW72_18180	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
CIW72_18205	ENOG4108RMV	DegV Family
CIW72_18210	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
CIW72_18240	ENOG4105EJG	cellulose synthase
CIW72_18245	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
CIW72_18250	ENOG4107EEX	Cellulose synthase regulator protein
CIW72_18255	ENOG4107QZ7	Cellulose synthase catalytic subunit
CIW72_18270	ENOG4107RH7	Nicotinate phosphoribosyltransferase
CIW72_18325	ENOG4106S9K	Transcriptional regulator
CIW72_18335	ENOG4105GVR	general secretion pathway protein D
CIW72_18345	ENOG410678M	general secretion pathway protein M
CIW72_18350	ENOG41090VX	general secretion pathway protein L
CIW72_18355	ENOG4105UV2	general secretion pathway protein K
CIW72_18360	ENOG41069G9	General secretion pathway protein J
CIW72_18370	ENOG4105WMT	general secretion pathway protein h
CIW72_18380	ENOG4105D7Q	type ii secretion system
CIW72_18390	ENOG4107QHF	type ii secretion system protein e
CIW72_18395	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
CIW72_18405	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
CIW72_18410	ENOG4105EUR	Domain-Containing protein
CIW72_18415	ENOG4108ETH	Formylglycinamide ribotide synthetase
CIW72_18430	ENOG4105T95	Thiol disulfide interChange protein
CIW72_18445	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CIW72_18460	ENOG4108K5H	permease YjgP YjgQ family protein
CIW72_18470	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
CIW72_18485	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
CIW72_18515	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
CIW72_18525	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
CIW72_18530	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
CIW72_18545	ENOG4105DHJ	ABC, transporter
CIW72_18550	ENOG4108SNX	Mammalian cell entry related domain protein
CIW72_18565	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
CIW72_18580	ENOG4107QKV	phosphomannomutase
CIW72_18585	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
CIW72_18595	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
CIW72_18600	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
CIW72_18615	ENOG4105BZJ	Electron transfer flavoprotein
CIW72_18620	ENOG4105C10	Electron transfer flavoprotein
CIW72_18660	ENOG4108DMA	Nad-dependent epimerase dehydratase
CIW72_18665	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
CIW72_18670	ENOG4105CGN	Glycosyl transferase (Group 1
CIW72_18680	ENOG4105EY8	ABC transporter
CIW72_18690	ENOG4107STW	synthase
CIW72_18700	ENOG4105C28	cystathionine
CIW72_18725	ENOG4105CZX	twitching motility protein
CIW72_18730	ENOG4108RXX	maleylacetoacetate isomerase
CIW72_18745	ENOG4105C1J	atp-dependent rna helicase
CIW72_18755	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
CIW72_18765	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
CIW72_18775	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
CIW72_18790	ENOG4105NIV	Esterase
CIW72_18795	ENOG4107RNH	Outer membrane receptor FepA
CIW72_18800	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
CIW72_18805	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
CIW72_18810	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
CIW72_18825	ENOG4105DGW	oligopeptidase A
CIW72_18875	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
CIW72_18880	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
CIW72_18885	ENOG4105C19	ABC transporter
CIW72_18890	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CIW72_18895	ENOG4107RBB	ABC transporter, permease
CIW72_18905	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CIW72_18910	ENOG4105BZU	Histidine kinase
CIW72_18915	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
CIW72_18930	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
CIW72_18935	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
CIW72_18940	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
CIW72_18945	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
CIW72_18950	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CIW72_18955	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CIW72_18960	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CIW72_18965	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
CIW72_18985	ENOG4107QN2	dihydrolipoyl dehydrogenase
CIW72_18995	ENOG4107QSN	dihydrolipoamide acetyltransferase
CIW72_19030	ENOG4105D01	(LipO)protein
CIW72_19035	ENOG4108UMI	ABC transporter, permease
CIW72_19040	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
CIW72_19045	ENOG4108EHX	EamA-like transporter family
CIW72_19050	ENOG4108VPT	UPF0234 protein
CIW72_19060	ENOG4105BZU	Histidine kinase
CIW72_19075	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
CIW72_19080	ENOG4107YBY	Hydrolase
CIW72_19085	ENOG4105I08	Pseudouridine synthase
CIW72_19090	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
CIW72_19115	ENOG4105BZU	Histidine kinase
CIW72_19135	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
CIW72_19140	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
CIW72_19145	ENOG4105EW9	transcriptional regulator AsnC family
CIW72_19165	ENOG4107RD7	Flagellar Motor Protein, MotA
CIW72_19170	ENOG4105ER2	Ompa motb domain protein
CIW72_19200	ENOG4105E3A	(ABC) transporter
CIW72_19205	ENOG4105DA5	(ABC) transporter
CIW72_19210	ENOG4105EEQ	Na H antiporter
CIW72_19225	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
CIW72_19235	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
CIW72_19245	ENOG4105CBN	LysR family transcriptional regulator
CIW72_19255	ENOG4105CPC	Aldo Keto reductase
CIW72_19270	ENOG4105C9K	Endothelin-converting enzyme 1
CIW72_19290	ENOG4107QTZ	amino acid
CIW72_19300	ENOG4108VAC	response regulator
CIW72_19305	ENOG4105C2F	Histidine kinase
CIW72_19330	ENOG4108Z9Z	response to DNA damage stimulus
CIW72_19335	ENOG4105WEF	catalase
CIW72_19355	ENOG4105BZU	Histidine kinase
CIW72_19370	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CIW72_19385	ENOG4105C4M	(Ubiquinol oxidase) subunit I
CIW72_19390	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
CIW72_19405	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
CIW72_19410	ENOG4105CMR	udp-glucose 4-epimerase
CIW72_19430	ENOG4105BZ1	(ABC) transporter
CIW72_19445	ENOG4105E2A	Dehydrogenase
CIW72_19505	ENOG4105CIG	ABC transporter
CIW72_19530	ENOG4105HEI	LysR family (Transcriptional regulator
CIW72_19535	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
CIW72_19605	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CIW72_19610	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
CIW72_19615	ENOG4105D1S	lipid A biosynthesis
CIW72_19625	ENOG4108Z7F	N-acetyltransferase
CIW72_19670	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
CIW72_19675	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
CIW72_19680	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
CIW72_19685	ENOG4108WZM	domain protein
CIW72_19690	ENOG4105C79	DNA protecting protein DprA
CIW72_19695	ENOG4108RPN	Protein smg homolog
CIW72_19710	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
CIW72_19715	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CIW72_19730	ENOG4107ZQV	short-chain dehydrogenase reductase
CIW72_19745	ENOG4105D07	Signal peptide peptidase, SppA
CIW72_19750	ENOG4107QI1	Mate efflux family protein
CIW72_19770	ENOG4105C25	Primosomal protein n'
CIW72_19775	ENOG4108TGY	Glutathione S-transferase
CIW72_19795	ENOG4105EN6	Membrane
CIW72_19800	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CIW72_19805	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
CIW72_19810	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CIW72_19815	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
CIW72_19820	ENOG4105CAK	Cell division ATP-binding protein ftsE
CIW72_19825	ENOG4105C1J	atp-dependent rna helicase
CIW72_19830	ENOG4105K63	Thioredoxin
CIW72_19835	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
CIW72_19845	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
CIW72_19850	ENOG4105ETT	transcriptional Regulator, LysR family
CIW72_19860	ENOG4105E9K	Isocitrate dehydrogenase
CIW72_19870	ENOG4109066	lysm domain bon superfamily protein
CIW72_19875	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
CIW72_19880	ENOG4105CH2	amidohydrolase
CIW72_19885	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
CIW72_19890	ENOG4105BZS	acriflavin resistance protein
CIW72_19900	ENOG4105E32	cytoplasmic protein
CIW72_19950	ENOG4108UQS	dipeptidase
CIW72_19955	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
CIW72_19965	ENOG4105DTQ	mandelate racemase muconate lactonizing
CIW72_19975	ENOG4105D5Q	Arginine ornithine antiporter
CIW72_19990	ENOG4108Z12	YiaAB two helix domain-containing protein
CIW72_20000	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
CIW72_20005	ENOG4107ZVW	dihydroneopterin aldolase
CIW72_20010	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CIW72_20015	ENOG4105VCC	30S ribosomal protein S21
CIW72_20020	ENOG4105KTH	gatB Yqey
CIW72_20030	ENOG4107S2Z	UPF0761 membrane protein
CIW72_20035	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
CIW72_20040	ENOG4105DHU	Bile acid
CIW72_20050	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
CIW72_20075	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
CIW72_20080	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
CIW72_20095	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
CIW72_20105	ENOG4105C26	Dehydrogenase
CIW72_20140	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
CIW72_20145	ENOG4105DR5	peptidase
CIW72_20150	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
CIW72_20160	ENOG4105EYM	Major Facilitator superfamily
CIW72_20165	ENOG4105CGK	Exodeoxyribonuclease III
CIW72_20170	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
CIW72_20180	ENOG4107QJE	Chromosome Partitioning Protein
CIW72_20185	ENOG4105FA0	parb-like partition protein
CIW72_20205	ENOG4105CKK	Glycosyl transferase, family 2
CIW72_20225	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
CIW72_20230	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
CIW72_20235	ENOG4105W5Q	DNA repair protein (RadC
CIW72_20240	ENOG4105C75	arginyL-tRNA synthetase
CIW72_20255	ENOG4105EMU	Dehydrogenase
CIW72_20260	ENOG4105EXC	Acyl-transferase
CIW72_20275	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
CIW72_20280	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
CIW72_20310	ENOG4108YZA	Nitrogen regulatory protein pii
CIW72_20315	ENOG4105W0Z	cytoplasmic protein
CIW72_20320	ENOG4105C0P	Mg chelatase subunit ChlI
CIW72_20335	ENOG41066DG	(EAL) domain protein
CIW72_20350	ENOG4105EJ2	Transcriptional regulator
CIW72_20375	ENOG4105E0Y	RtcB Protein
CIW72_20410	ENOG4105ECP	epimerase
CIW72_20415	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
CIW72_20420	ENOG4105DHQ	Histidine kinase
CIW72_20450	ENOG4105C0H	protease
CIW72_20470	ENOG4105DSF	transport protein
CIW72_20475	ENOG4107URF	beta-phospho-glucomutase
CIW72_20480	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
CIW72_20495	ENOG4107VGR	Catalase
CIW72_20510	ENOG4108S01	response regulator
CIW72_20515	ENOG4108ZGX	Histidine kinase
CIW72_20520	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
CIW72_20525	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CIW72_20570	ENOG4108NNI	Beta-lactamase domain-containing protein
CIW72_20575	ENOG4105C31	Tryptophanyl-tRNA synthetase
CIW72_20580	ENOG4105VDW	Csbd family
CIW72_20680	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
CIW72_20720	ENOG4105EB3	Histidine kinase
CIW72_20725	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
CIW72_20735	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
CIW72_20755	ENOG4105CH6	catalase
CIW72_20765	ENOG4105DVT	helicase
CIW72_20780	ENOG4105E2X	shikimate dehydrogenase
CIW72_20790	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
CIW72_20815	ENOG4105D52	delta-aminolevulinic acid dehydratase
CIW72_20845	ENOG4105CYM	Glutathione S-transferase
CIW72_20870	ENOG4105QV4	Tryptophan halogenase
CIW72_20885	ENOG4108IUW	ABC transporter
CIW72_20895	ENOG4105VZ8	Transcriptional regulator
CIW72_20915	ENOG4105PGM	cation diffusion facilitator family transporter
CIW72_20925	ENOG4105E0K	tonB-dependent siderophore receptor
CIW72_20935	ENOG4105ECQ	AraC Family Transcriptional Regulator
CIW72_20940	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
CIW72_20945	ENOG4105DA5	(ABC) transporter
CIW72_20950	ENOG4105E3A	(ABC) transporter
CIW72_20960	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
CIW72_20990	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CIW72_21000	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CIW72_21025	ENOG4105CJW	magnesium transporter
CIW72_21045	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
CIW72_21050	ENOG4105BZP	glycoside hydrolase 15-related
CIW72_21070	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
CIW72_21080	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
CIW72_21140	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
CIW72_21145	ENOG4105E9Q	Acyl-transferase
CIW72_21155	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
CIW72_21185	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
CIW72_21205	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
CIW72_21215	ENOG4105C2M	dna polymerase I
CIW72_21250	ENOG4108ZF3	Phosphatase
CIW72_21285	ENOG4105CS6	Rhs element vgr protein
CIW72_21330	ENOG4105D6F	Phosphatase
CIW72_21360	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CIW72_21420	ENOG4105C4R	Atp-dependent dna helicase
CIW72_21435	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
CIW72_21445	ENOG4105JSC	dimethylmenaquinone methyltransferase
CIW72_21460	ENOG4105KHM	amidohydrolase 2
CIW72_21465	ENOG4105W0E	50S ribosomal protein L33
CIW72_21470	ENOG4105KDC	50s ribosomal protein l28
CIW72_21485	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
CIW72_21505	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
CIW72_21510	ENOG4105DGI	Alkaline phosphatase
CIW72_21535	ENOG4105CGK	Exodeoxyribonuclease III
CIW72_21540	ENOG4105E2R	ROK family
CIW72_21550	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
CIW72_21560	ENOG4107QN1	sodium solute
CIW72_21565	ENOG41062QD	Membrane
CIW72_21575	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
CIW72_21605	ENOG4105DSG	hydrolase family 43
CIW72_21625	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
CIW72_21630	ENOG4105ERH	Fumarylacetoacetate hydrolase
CIW72_21640	ENOG4105DIA	mandelate racemase muconate lactonizing
CIW72_21645	ENOG4105QJH	Domain of unknown function (DUF718)
CIW72_21650	ENOG4105EDR	glucose galactose transporter
CIW72_21655	ENOG4108K2P	TRANSCRIPTIONal
CIW72_21665	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
CIW72_21670	ENOG4105BZU	Histidine kinase
CIW72_21685	ENOG4105E2V	Glycosyltransferase 36
CIW72_21690	ENOG4105CT4	transporter
CIW72_21695	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
CIW72_21735	ENOG4105MA0	exported protein
CIW72_21740	ENOG4105CFU	surface antigen
CIW72_21745	ENOG4105D05	Receptor
CIW72_21750	ENOG4107RDJ	Sulfotransferase
CIW72_21760	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
CIW72_21765	ENOG4107QHF	type ii secretion system protein e
CIW72_21780	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
CIW72_21790	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
CIW72_21795	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
CIW72_21810	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
CIW72_21835	ENOG4105DH7	May be involved in recombination (By similarity)
CIW72_21840	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
CIW72_21850	ENOG4105C93	Xylose Isomerase
CIW72_21855	ENOG4105ETE	Transcriptional regulator (LacI family
CIW72_21860	ENOG4105D0H	Alpha-glucuronidase (EC 3.2.1.139)
CIW72_21870	ENOG4105CXK	mandelate racemase muconate lactonizing
CIW72_21885	ENOG4105DEI	Mannitol dehydrogenase
CIW72_21935	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
CIW72_21970	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
CIW72_21975	ENOG4105CNT	hydrolase family 2
CIW72_21980	ENOG4105D2H	Uronic isomerase
CIW72_22010	ENOG4105CT4	transporter
CIW72_22015	ENOG4105DT9	hydrolase family 43
CIW72_22040	ENOG4105DJ9	glucan biosynthesis protein
CIW72_22045	ENOG4105BZU	Histidine kinase
CIW72_22050	ENOG4107104	thymidine kinase
CIW72_22055	ENOG4105C4R	Atp-dependent dna helicase
CIW72_22060	ENOG4105KNA	-acetyltransferase
CIW72_22070	ENOG4108YXG	UPF0502 protein
CIW72_22080	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
CIW72_22085	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
CIW72_22090	ENOG4105QV4	Tryptophan halogenase
CIW72_22105	ENOG4105ETE	Transcriptional regulator (LacI family
CIW72_22120	ENOG4105E55	glycerol-3-phosphate acyltransferase
CIW72_22135	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
CIW72_22165	ENOG4105DKK	Benzoate
CIW72_22185	ENOG4105DSB	aldose 1-epimerase
CIW72_22195	ENOG4105K5B	UPF0225 protein
CIW72_22200	ENOG4105EJ9	Membrane
CIW72_22220	ENOG4105EUJ	GTP cyclohydrolase i
CIW72_22230	ENOG4105ZQC	membrane protein AaeX
CIW72_22235	ENOG4105Y49	secretion protein, HlyD family
CIW72_22245	ENOG4105DR8	Membrane
CIW72_22250	ENOG4105CSH	Transporter
CIW72_22260	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
CIW72_22325	ENOG4107QKA	exodeoxyribonuclease V beta
CIW72_22330	ENOG4105DSY	exodeoxyribonuclease V, gamma
CIW72_22345	ENOG4105DHJ	ABC, transporter
CIW72_22350	ENOG4105CY3	ABC transporter, permease
CIW72_22355	ENOG4107PE3	Mammalian cell entry related domain protein
CIW72_22370	ENOG410903C	(LipO)protein
CIW72_22380	ENOG4108V06	Glutathione peroxidase
CIW72_22390	ENOG4107QSV	RmuC domain protein
CIW72_22395	ENOG4105CIS	alcohol dehydrogenase
CIW72_22400	ENOG4105SKE	transcriptional Regulator LysR family
CIW72_22415	ENOG4108TGY	Glutathione S-transferase
CIW72_22425	ENOG4105CUB	amino acid
CIW72_22440	ENOG4105NRM	Membrane
CIW72_22445	ENOG4105BZU	Histidine kinase
CIW72_22465	ENOG4105DR4	Methyltransferase
CIW72_22475	ENOG4105DU1	integral membrane protein, terc
CIW72_22490	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
CIW72_22505	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
CIW72_22510	ENOG4108ZJ4	polysaccharide deacetylase
CIW72_22515	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CIW72_22520	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
CIW72_22705	ENOG4108C33	Resolvase
CIW72_22755	ENOG4108C33	Resolvase
CIW72_22775	ENOG4106RHG	Yeca family
CIW72_22875	ENOG4105XMH	SpoVT AbrB domain protein
CIW72_22935	ENOG4105CVE	Lytic murein transglycosylase
CIW72_22975	ENOG4106RHG	Yeca family
CIW72_22995	ENOG4108C33	Resolvase
CIW72_23030	ENOG4108C33	Resolvase
CIW72_23050	ENOG4106RHG	Yeca family