locus-tag	class	description
APY29_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
APY29_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
APY29_00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
APY29_00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
APY29_00030	ENOG4108K0D	peptidase, M48
APY29_00060	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
APY29_00070	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
APY29_00110	ENOG4105W5Q	DNA repair protein (RadC
APY29_00125	ENOG4105CMM	transposase
APY29_00185	ENOG4105CN1	protease
APY29_00190	ENOG41063SB	peptidase
APY29_00200	ENOG4107VAM	peptidase, m28
APY29_00230	ENOG4105DQ4	alcohol dehydrogenase
APY29_00235	ENOG4105BZ8	glutamate synthase
APY29_00240	ENOG4105CBC	glutamate synthase
APY29_00285	ENOG4105D3Q	Sugar transferase
APY29_00290	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
APY29_00300	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
APY29_00305	ENOG4107RA4	Glycosyl transferase (Group 1
APY29_00325	ENOG4105CAQ	asparagine synthetase
APY29_00340	ENOG4105CMR	udp-glucose 4-epimerase
APY29_00355	ENOG4105BZ1	(ABC) transporter
APY29_00385	ENOG4107W2Z	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) (By similarity)
APY29_00465	ENOG4108I5C	dEAD DEAH box helicase
APY29_00470	ENOG4108UT2	hemolysin iii
APY29_00485	ENOG4107FW0	short-chain dehydrogenase reductase
APY29_00490	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
APY29_00530	ENOG4105RKW	reductase (By
APY29_00535	ENOG4108M3R	transcriptional activator CadC
APY29_00555	ENOG4105WH1	Two component transcriptional regulator luxr family
APY29_00560	ENOG4105BZU	Histidine kinase
APY29_00570	ENOG4105DMF	Dehydrogenase
APY29_00625	ENOG41082W1	Cupin 2, conserved barrel domain protein
APY29_00635	ENOG4105CHB	tonB-dependent Receptor
APY29_00640	ENOG4105CGF	Aromatic amino acid aminotransferase
APY29_00645	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
APY29_00675	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
APY29_00725	ENOG4105K63	Thioredoxin
APY29_00775	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
APY29_00780	ENOG4105CG3	alpha amylase, catalytic region
APY29_00785	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
APY29_00870	ENOG4105CMA	conjugation trbi family protein
APY29_00935	ENOG4105VXN	addiction module toxin, RelE StbE family
APY29_01000	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
APY29_01005	ENOG4105CT4	transporter
APY29_01010	ENOG4105E2V	Glycosyltransferase 36
APY29_01025	ENOG4105BZU	Histidine kinase
APY29_01030	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
APY29_01040	ENOG4108K2P	TRANSCRIPTIONal
APY29_01045	ENOG4105EDR	glucose galactose transporter
APY29_01050	ENOG4105QJH	Domain of unknown function (DUF718)
APY29_01055	ENOG4105DIA	mandelate racemase muconate lactonizing
APY29_01060	ENOG4105ERH	Fumarylacetoacetate hydrolase
APY29_01065	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
APY29_01115	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
APY29_01125	ENOG41062QD	Membrane
APY29_01130	ENOG4107QN1	sodium solute
APY29_01140	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
APY29_01150	ENOG4105E2R	ROK family
APY29_01155	ENOG4105CGK	Exodeoxyribonuclease III
APY29_01185	ENOG4105DGI	Alkaline phosphatase
APY29_01190	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
APY29_01210	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
APY29_01225	ENOG4105KDC	50s ribosomal protein l28
APY29_01230	ENOG4105W0E	50S ribosomal protein L33
APY29_01235	ENOG4105KHM	amidohydrolase 2
APY29_01245	ENOG4105JSC	dimethylmenaquinone methyltransferase
APY29_01250	ENOG4108KB2	LysR family Transcriptional regulator
APY29_01255	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
APY29_01270	ENOG4105C4R	Atp-dependent dna helicase
APY29_01305	ENOG4108WC9	type VI secretion system effector, hcp1 family
APY29_01330	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
APY29_01365	ENOG4105D6F	Phosphatase
APY29_01405	ENOG4105CS6	Rhs element vgr protein
APY29_01440	ENOG4108ZF3	Phosphatase
APY29_01445	ENOG4105D9P	serine threonine protein kinase
APY29_01475	ENOG4105C2M	dna polymerase I
APY29_01485	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
APY29_01500	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
APY29_01525	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
APY29_01535	ENOG4105E9Q	Acyl-transferase
APY29_01540	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
APY29_01595	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
APY29_01605	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
APY29_01625	ENOG4105BZP	glycoside hydrolase 15-related
APY29_01630	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
APY29_01645	ENOG4105CJW	magnesium transporter
APY29_01650	ENOG4105CD5	CoA-binding domain protein
APY29_01660	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
APY29_01665	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
APY29_01695	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
APY29_01705	ENOG4105E3A	(ABC) transporter
APY29_01710	ENOG4105DA5	(ABC) transporter
APY29_01715	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
APY29_01720	ENOG4105ECQ	AraC Family Transcriptional Regulator
APY29_01730	ENOG4105E0K	tonB-dependent siderophore receptor
APY29_01740	ENOG4105PGM	cation diffusion facilitator family transporter
APY29_01760	ENOG4105VZ8	Transcriptional regulator
APY29_01770	ENOG4108IUW	ABC transporter
APY29_01785	ENOG4105QV4	Tryptophan halogenase
APY29_01810	ENOG4105CYM	Glutathione S-transferase
APY29_01855	ENOG4105D52	delta-aminolevulinic acid dehydratase
APY29_01875	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
APY29_01885	ENOG4105E2X	shikimate dehydrogenase
APY29_01900	ENOG4105DVT	helicase
APY29_01905	ENOG4105CH6	catalase
APY29_01920	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
APY29_01930	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
APY29_01935	ENOG4105EB3	Histidine kinase
APY29_01960	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
APY29_02040	ENOG4105VDW	Csbd family
APY29_02045	ENOG4105C31	Tryptophanyl-tRNA synthetase
APY29_02050	ENOG4108NNI	Beta-lactamase domain-containing protein
APY29_02065	ENOG4105FDR	Membrane
APY29_02090	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
APY29_02095	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
APY29_02100	ENOG4108ZGX	Histidine kinase
APY29_02105	ENOG4108S01	response regulator
APY29_02120	ENOG4107VGR	Catalase
APY29_02135	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
APY29_02140	ENOG4107URF	beta-phospho-glucomutase
APY29_02145	ENOG4105DSF	transport protein
APY29_02165	ENOG4105C0H	protease
APY29_02185	ENOG4105DHQ	Histidine kinase
APY29_02190	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
APY29_02195	ENOG4105ECP	epimerase
APY29_02235	ENOG4105E0Y	RtcB Protein
APY29_02255	ENOG4105EJ2	Transcriptional regulator
APY29_02270	ENOG41066DG	(EAL) domain protein
APY29_02285	ENOG4105C0P	Mg chelatase subunit ChlI
APY29_02290	ENOG4105W0Z	cytoplasmic protein
APY29_02295	ENOG4108YZA	Nitrogen regulatory protein pii
APY29_02325	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
APY29_02330	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
APY29_02340	ENOG4105CEY	Amp-dependent synthetase and ligase
APY29_02355	ENOG4105EMU	Dehydrogenase
APY29_02370	ENOG4105C75	arginyL-tRNA synthetase
APY29_02375	ENOG4105W5Q	DNA repair protein (RadC
APY29_02380	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
APY29_02385	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
APY29_02405	ENOG4105CKK	Glycosyl transferase, family 2
APY29_02420	ENOG4105FA0	parb-like partition protein
APY29_02425	ENOG4107QJE	Chromosome Partitioning Protein
APY29_02435	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
APY29_02440	ENOG4105CGK	Exodeoxyribonuclease III
APY29_02445	ENOG4105EYM	Major Facilitator superfamily
APY29_02455	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
APY29_02460	ENOG4105DR5	peptidase
APY29_02465	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
APY29_02500	ENOG4105C26	Dehydrogenase
APY29_02510	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
APY29_02520	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
APY29_02525	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
APY29_02550	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
APY29_02560	ENOG4105DHU	Bile acid
APY29_02565	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
APY29_02570	ENOG4107S2Z	UPF0761 membrane protein
APY29_02575	ENOG4105KTH	gatB Yqey
APY29_02580	ENOG4105VCC	30S ribosomal protein S21
APY29_02585	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
APY29_02590	ENOG4107ZVW	dihydroneopterin aldolase
APY29_02595	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
APY29_02605	ENOG4108Z12	YiaAB two helix domain-containing protein
APY29_02620	ENOG4105D5Q	Arginine ornithine antiporter
APY29_02630	ENOG4105DTQ	mandelate racemase muconate lactonizing
APY29_02640	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
APY29_02645	ENOG4108UQS	dipeptidase
APY29_02685	ENOG4105E32	cytoplasmic protein
APY29_02695	ENOG4105BZS	acriflavin resistance protein
APY29_02700	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
APY29_02705	ENOG4105CH2	amidohydrolase
APY29_02710	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
APY29_02725	ENOG4105E9K	Isocitrate dehydrogenase
APY29_02735	ENOG4105ETT	transcriptional Regulator, LysR family
APY29_02740	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
APY29_02750	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
APY29_02755	ENOG4105K63	Thioredoxin
APY29_02760	ENOG4105C1J	atp-dependent rna helicase
APY29_02765	ENOG4105CAK	Cell division ATP-binding protein ftsE
APY29_02770	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
APY29_02775	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
APY29_02780	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
APY29_02785	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
APY29_02790	ENOG4105EN6	Membrane
APY29_02810	ENOG4108TGY	Glutathione S-transferase
APY29_02815	ENOG4105C25	Primosomal protein n'
APY29_02835	ENOG4107QI1	Mate efflux family protein
APY29_02840	ENOG4105D07	Signal peptide peptidase, SppA
APY29_02850	ENOG4107ZQV	short-chain dehydrogenase reductase
APY29_02865	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
APY29_02870	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
APY29_02885	ENOG4108RPN	Protein smg homolog
APY29_02890	ENOG4105C79	DNA protecting protein DprA
APY29_02895	ENOG4108WZM	domain protein
APY29_02900	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
APY29_02905	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
APY29_02910	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
APY29_02955	ENOG4108Z7F	N-acetyltransferase
APY29_02960	ENOG4105D1S	lipid A biosynthesis
APY29_02965	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
APY29_02970	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
APY29_03020	ENOG4105C0D	helicase
APY29_03095	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
APY29_03100	ENOG4105HEI	LysR family (Transcriptional regulator
APY29_03120	ENOG4105CIG	ABC transporter
APY29_03180	ENOG4105E2A	Dehydrogenase
APY29_03195	ENOG4105BZ1	(ABC) transporter
APY29_03215	ENOG4105CMR	udp-glucose 4-epimerase
APY29_03220	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
APY29_03235	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
APY29_03240	ENOG4105C4M	(Ubiquinol oxidase) subunit I
APY29_03250	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
APY29_03285	ENOG4105WEF	catalase
APY29_03290	ENOG4108Z9Z	response to DNA damage stimulus
APY29_03300	ENOG4105MP0	transposase
APY29_03315	ENOG4105C2F	Histidine kinase
APY29_03320	ENOG4108VAC	response regulator
APY29_03330	ENOG4107QTZ	amino acid
APY29_03350	ENOG4105C9K	Endothelin-converting enzyme 1
APY29_03360	ENOG4105CPC	Aldo Keto reductase
APY29_03370	ENOG4105CBN	LysR family transcriptional regulator
APY29_03380	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
APY29_03390	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
APY29_03400	ENOG4105EEQ	Na H antiporter
APY29_03405	ENOG4105DA5	(ABC) transporter
APY29_03410	ENOG4105E3A	(ABC) transporter
APY29_03435	ENOG4105ER2	Ompa motb domain protein
APY29_03440	ENOG4107RD7	Flagellar Motor Protein, MotA
APY29_03460	ENOG4105EW9	transcriptional regulator AsnC family
APY29_03465	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
APY29_03470	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
APY29_03490	ENOG4105BZU	Histidine kinase
APY29_03515	ENOG4105I08	Pseudouridine synthase
APY29_03520	ENOG4107YBY	Hydrolase
APY29_03525	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
APY29_03545	ENOG4105BZU	Histidine kinase
APY29_03555	ENOG4108VPT	UPF0234 protein
APY29_03560	ENOG4108EHX	EamA-like transporter family
APY29_03565	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
APY29_03570	ENOG4108UMI	ABC transporter, permease
APY29_03575	ENOG4105D01	(LipO)protein
APY29_03620	ENOG4107QSN	dihydrolipoamide acetyltransferase
APY29_03630	ENOG4107QN2	dihydrolipoyl dehydrogenase
APY29_03650	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
APY29_03655	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
APY29_03660	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
APY29_03665	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
APY29_03670	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
APY29_03675	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
APY29_03680	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
APY29_03685	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
APY29_03700	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
APY29_03705	ENOG4105BZU	Histidine kinase
APY29_03710	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
APY29_03720	ENOG4107RBB	ABC transporter, permease
APY29_03725	ENOG4107RBB	ABC transporter, permease
APY29_03730	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
APY29_03735	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
APY29_03740	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
APY29_03760	ENOG4105MP0	transposase
APY29_03800	ENOG4105DGW	oligopeptidase A
APY29_03815	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
APY29_03820	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
APY29_03825	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
APY29_03830	ENOG4107RNH	Outer membrane receptor FepA
APY29_03835	ENOG4105NIV	Esterase
APY29_03850	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
APY29_03860	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
APY29_03865	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
APY29_03875	ENOG4105C1J	atp-dependent rna helicase
APY29_03885	ENOG4108RXX	maleylacetoacetate isomerase
APY29_03890	ENOG4105CZX	twitching motility protein
APY29_03915	ENOG4105C28	cystathionine
APY29_03925	ENOG4107STW	synthase
APY29_03935	ENOG4105EY8	ABC transporter
APY29_03945	ENOG4105CGN	Glycosyl transferase (Group 1
APY29_03950	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
APY29_03955	ENOG4108DMA	Nad-dependent epimerase dehydratase
APY29_04015	ENOG4105C10	Electron transfer flavoprotein
APY29_04020	ENOG4105BZJ	Electron transfer flavoprotein
APY29_04035	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
APY29_04040	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
APY29_04050	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
APY29_04055	ENOG4107QKV	phosphomannomutase
APY29_04070	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
APY29_04085	ENOG4108SNX	Mammalian cell entry related domain protein
APY29_04090	ENOG4105DHJ	ABC, transporter
APY29_04105	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
APY29_04110	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
APY29_04120	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
APY29_04150	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
APY29_04175	ENOG4108K5H	permease YjgP YjgQ family protein
APY29_04190	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
APY29_04195	ENOG4105T95	Thiol disulfide interChange protein
APY29_04200	ENOG4108ETH	Formylglycinamide ribotide synthetase
APY29_04205	ENOG4105EUR	Domain-Containing protein
APY29_04210	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
APY29_04215	ENOG4105EUR	Domain-Containing protein
APY29_04220	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
APY29_04225	ENOG4107QHF	type ii secretion system protein e
APY29_04230	ENOG4105D7Q	type ii secretion system
APY29_04240	ENOG4105WMT	general secretion pathway protein h
APY29_04250	ENOG41069G9	General secretion pathway protein J
APY29_04255	ENOG4105UV2	general secretion pathway protein K
APY29_04260	ENOG41090VX	general secretion pathway protein L
APY29_04265	ENOG410678M	general secretion pathway protein M
APY29_04275	ENOG4105GVR	general secretion pathway protein D
APY29_04285	ENOG4105CMM	transposase
APY29_04295	ENOG4106S9K	Transcriptional regulator
APY29_04345	ENOG4107RH7	Nicotinate phosphoribosyltransferase
APY29_04360	ENOG4107QZ7	Cellulose synthase catalytic subunit
APY29_04365	ENOG4107EEX	Cellulose synthase regulator protein
APY29_04370	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
APY29_04375	ENOG4105EJG	cellulose synthase
APY29_04400	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
APY29_04405	ENOG4108RMV	DegV Family
APY29_04425	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
APY29_04430	ENOG41069H0	dihydroorotase EC 3.5.2.3
APY29_04455	ENOG4105CNM	Receptor
APY29_04475	ENOG4108JJA	ABC, transporter
APY29_04495	ENOG4105CMM	transposase
APY29_04535	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
APY29_04550	ENOG4107QW3	Sucrose phosphorylase
APY29_04565	ENOG4105ETE	Transcriptional regulator (LacI family
APY29_04570	ENOG4105CHR	reductase
APY29_04575	ENOG4105D4T	Citrate transporter
APY29_04590	ENOG4105DHQ	Histidine kinase
APY29_04595	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
APY29_04600	ENOG4105WH1	Two component transcriptional regulator luxr family
APY29_04615	ENOG4105CPC	Aldo Keto reductase
APY29_04625	ENOG4105F04	LysR family Transcriptional regulator
APY29_04635	ENOG4105CSH	Transporter
APY29_04640	ENOG4105CQZ	Histidine kinase
APY29_04655	ENOG4105CK2	sodium dicarboxylate symporter
APY29_04660	ENOG4105C6K	Malic enzyme
APY29_04685	ENOG4105D1S	lipid A biosynthesis
APY29_04690	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
APY29_04695	ENOG4105DFG	type I secretion outer membrane protein
APY29_04700	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
APY29_04715	ENOG4108MP6	LysR family Transcriptional regulator
APY29_04720	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
APY29_04725	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
APY29_04730	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
APY29_04735	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
APY29_04740	ENOG4105C7B	Threonine dehydratase
APY29_04755	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
APY29_04760	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
APY29_04765	ENOG4105C8Q	Methyl-accepting chemotaxis
APY29_04775	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
APY29_04780	ENOG4108M3R	transcriptional activator CadC
APY29_04785	ENOG4105ECQ	AraC Family Transcriptional Regulator
APY29_04800	ENOG4105F0N	pyrophosphate phospho-hydrolase
APY29_04810	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
APY29_04815	ENOG4105MP0	transposase
APY29_04835	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
APY29_04840	ENOG4105DFU	Cell wall formation (By similarity)
APY29_04850	ENOG4105FFC	UPF0187 protein
APY29_04855	ENOG410841Q	phosphoesterase PA-phosphatase related protein
APY29_04870	ENOG4105EYW	Ion transport protein
APY29_04875	ENOG4105C8Y	Acetylornithine aminotransferase
APY29_04905	ENOG4105CIH	Imidazole acetol-phosphate transaminase
APY29_04920	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
APY29_04930	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
APY29_04935	ENOG4105VCQ	rubredoxin
APY29_04940	ENOG41063JG	Transcriptional regulator
APY29_04950	ENOG4105E66	phosphoriboisomerase A
APY29_04960	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
APY29_04965	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
APY29_04980	ENOG4107RAQ	aminopeptidase
APY29_04990	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
APY29_05005	ENOG4105CSA	Coproporphyrinogen iii oxidase
APY29_05010	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
APY29_05020	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
APY29_05025	ENOG4105DSJ	YicC domain protein
APY29_05030	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
APY29_05035	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
APY29_05040	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
APY29_05045	ENOG4105KME	endoribonuclease L-psp
APY29_05050	ENOG4105CB5	ATP-dependent DNA helicase recG
APY29_05055	ENOG4105DU0	nucleoside hydrolase
APY29_05060	ENOG4105NRA	50s ribosomal protein l31 type b
APY29_05075	ENOG4108JQC	penicillin-binding protein 1A
APY29_05105	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
APY29_05125	ENOG4107QVM	von Willebrand factor, type A
APY29_05135	ENOG4105CK2	sodium dicarboxylate symporter
APY29_05140	ENOG4105CV1	Transketolase (EC 2.2.1.1)
APY29_05160	ENOG4105CNM	Receptor
APY29_05215	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
APY29_05220	ENOG4105E0C	molybdate abc transporter
APY29_05225	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
APY29_05230	ENOG4107S76	domain protein
APY29_05240	ENOG4105EIF	outer membrane protein W
APY29_05245	ENOG4105EIF	outer membrane protein W
APY29_05255	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
APY29_05275	ENOG4105BZA	Phosphoglycerate kinase
APY29_05285	ENOG4105CA9	Pyruvate kinase
APY29_05290	ENOG4107R1Y	fructose-bisphosphate aldolase
APY29_05295	ENOG4108UVJ	appr-1-p processing domain protein
APY29_05310	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
APY29_05315	ENOG4107R11	Transcriptional regulator
APY29_05330	ENOG4105BZU	Histidine kinase
APY29_05350	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
APY29_05355	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
APY29_05360	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
APY29_05365	ENOG4105C11	sulfate adenylyltransferase), subunit 2
APY29_05370	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
APY29_05380	ENOG4105BZS	acriflavin resistance protein
APY29_05410	ENOG4105CD8	aminopeptidase N
APY29_05420	ENOG4105EIB	trna rrna methyltransferase
APY29_05450	ENOG4105ETE	Transcriptional regulator (LacI family
APY29_05465	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
APY29_05490	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
APY29_05495	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
APY29_05575	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
APY29_05585	ENOG4105ETX	regulatoR
APY29_05590	ENOG4105BZU	Histidine kinase
APY29_05605	ENOG4105CMM	transposase
APY29_05625	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
APY29_05630	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
APY29_05645	ENOG4107QHF	type ii secretion system protein e
APY29_05650	ENOG4107QHF	type ii secretion system protein e
APY29_05655	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
APY29_05665	ENOG4107TUY	Histidine kinase
APY29_05670	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
APY29_05675	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
APY29_05690	ENOG4105C4K	Nad synthetase
APY29_05700	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
APY29_05705	ENOG4105C34	Pseudouridine synthase
APY29_05720	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
APY29_05725	ENOG4105C8Q	Methyl-accepting chemotaxis
APY29_05730	ENOG4105DZG	Dehydrogenase
APY29_05735	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
APY29_05740	ENOG4105BZP	glycoside hydrolase 15-related
APY29_05745	ENOG4108K4C	ec 3.1.3.12
APY29_05750	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
APY29_05785	ENOG41082IR	Excinuclease ABC C subunit domain protein
APY29_05790	ENOG4107ZSV	Receptor
APY29_05800	ENOG4105CPC	Aldo Keto reductase
APY29_05805	ENOG4105GVF	(ABC) transporter
APY29_05810	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
APY29_05815	ENOG4105E2Y	ABC, transporter
APY29_05820	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
APY29_05825	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
APY29_05840	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
APY29_05845	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
APY29_05855	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
APY29_05860	ENOG4108YZT	Adenosylcobinamide kinase
APY29_05865	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
APY29_05885	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
APY29_05895	ENOG4105C6X	Major Facilitator
APY29_05910	ENOG4105GAV	receptor
APY29_05935	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
APY29_05945	ENOG4107RNH	Outer membrane receptor FepA
APY29_05965	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
APY29_05980	ENOG4105ETT	transcriptional Regulator, LysR family
APY29_06000	ENOG4108ISG	Major Facilitator
APY29_06015	ENOG4105C9M	aspartyl-trna synthetase
APY29_06030	ENOG4105CDY	transcriptional regulatory protein
APY29_06035	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
APY29_06040	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
APY29_06045	ENOG4105DFH	Transport of potassium into the cell (By similarity)
APY29_06055	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
APY29_06060	ENOG4107YD3	Thioesterase
APY29_06065	ENOG4105E02	MotA TolQ exbB proton channel
APY29_06080	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
APY29_06085	ENOG4105KCK	Peptidoglycan-associated lipoprotein
APY29_06095	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
APY29_06105	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
APY29_06110	ENOG410903D	sensor protein
APY29_06130	ENOG4105C8Q	Methyl-accepting chemotaxis
APY29_06165	ENOG4105C9U	ATP-dependent DNA helicase RecQ
APY29_06175	ENOG4105CQ7	ATP-dependent helicase
APY29_06185	ENOG4105CHC	glucokinase (EC 2.7.1.2)
APY29_06200	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
APY29_06205	ENOG4105Z85	coenzyme PQQ synthesis
APY29_06210	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
APY29_06215	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
APY29_06220	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
APY29_06235	ENOG4105BZ4	penicillin-binding protein
APY29_06245	ENOG4105DVT	helicase
APY29_06250	ENOG41072GX	Peptidase M22 Glycoprotease
APY29_06255	ENOG41065RQ	ADP-ribosylation crystallin J1
APY29_06265	ENOG4105D7Z	glutathione synthase
APY29_06270	ENOG4108UNF	response regulator
APY29_06275	ENOG4105M3Z	response regulator
APY29_06280	ENOG410807Z	Modulation of CheA activity in response to attractants (Chemotaxis
APY29_06285	ENOG4105C8Q	Methyl-accepting chemotaxis
APY29_06305	ENOG4105D9U	N-acetyltransferase
APY29_06320	ENOG4106N3A	copper homeostasis protein cutc
APY29_06355	ENOG4105CWX	Alpha-1,2-mannosidase
APY29_06395	ENOG4105MP0	transposase
APY29_06415	ENOG4105E2D	ec 3.2.1.52
APY29_06420	ENOG4105VRS	hydrolase family 18
APY29_06440	ENOG4105CHC	glucokinase (EC 2.7.1.2)
APY29_06445	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
APY29_06455	ENOG4107RK2	ADP-ribose diphosphatase NudE
APY29_06460	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
APY29_06465	ENOG4105DXN	mazG family
APY29_06470	ENOG4105KK4	UPF0060 membrane protein
APY29_06480	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
APY29_06485	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
APY29_06515	ENOG4107QPN	acyl-Coa dehydrogenase
APY29_06525	ENOG4108IG5	Transcriptional regulator
APY29_06550	ENOG4105CMM	transposase
APY29_06570	ENOG4105D05	Receptor
APY29_06580	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
APY29_06585	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
APY29_06595	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
APY29_06600	ENOG41066T0	asmA family
APY29_06605	ENOG4108UT2	hemolysin iii
APY29_06610	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
APY29_06615	ENOG4105DR5	peptidase
APY29_06620	ENOG4106TYC	homoserine o-acetyltransferase (EC 2.3.1.31)
APY29_06625	ENOG4105C28	cystathionine
APY29_06630	ENOG4105CFH	Aspartokinase
APY29_06640	ENOG4105EJQ	L-serine dehydratase
APY29_06660	ENOG4108YYC	ycei family
APY29_06665	ENOG4105BZU	Histidine kinase
APY29_06675	ENOG4105BZU	Histidine kinase
APY29_06680	ENOG4105BZU	Histidine kinase
APY29_06690	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
APY29_06700	ENOG4105D49	3-dehydroquinate synthase
APY29_06705	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
APY29_06710	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
APY29_06720	ENOG4108P9J	Phage shock protein A
APY29_06745	ENOG4106032	Glutathionylspermidine synthase
APY29_06765	ENOG4105MP0	transposase
APY29_06775	ENOG4108Z4X	TRANSCRIPTIONal
APY29_06805	ENOG4105QV4	Tryptophan halogenase
APY29_06835	ENOG4105CUB	amino acid
APY29_06860	ENOG4105CMM	transposase
APY29_06875	ENOG4105C85	amino acid
APY29_06885	ENOG4105C4M	(Ubiquinol oxidase) subunit I
APY29_06890	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
APY29_06895	ENOG4107UWA	esterase
APY29_06900	ENOG4105CJW	magnesium transporter
APY29_06910	ENOG41080Z8	PHOSPHOCARRIER protein
APY29_06920	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
APY29_06925	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
APY29_06930	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
APY29_06935	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
APY29_06940	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
APY29_06945	ENOG4108IUZ	ABC transporter
APY29_06950	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
APY29_06960	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
APY29_06965	ENOG4105C2X	Arabinose 5-phosphate isomerase
APY29_06975	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
APY29_06995	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
APY29_07010	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
APY29_07020	ENOG4105C02	permease
APY29_07030	ENOG4108S0S	Nucleotidyl transferase
APY29_07035	ENOG4105EHM	Aminoglycoside phosphotransferase
APY29_07050	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
APY29_07065	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
APY29_07070	ENOG4105CJ2	(LipO)protein
APY29_07095	ENOG4107E2E	PKHD-type hydroxylase
APY29_07100	ENOG4108IU3	tonb-dependent siderophore receptor
APY29_07115	ENOG4105C9B	Cysteine desulfurase
APY29_07120	ENOG4105JRK	feS assembly protein SufD
APY29_07125	ENOG4105C3K	feS assembly ATPase SufC
APY29_07145	ENOG4108Z0Z	intracellular protease Pfpi family
APY29_07165	ENOG4105FAA	peptidase M23
APY29_07175	ENOG4105II7	pyrroline-5-carboxylate reductase
APY29_07180	ENOG4105DFA	alanine racemase domain protein
APY29_07185	ENOG4105CZX	twitching motility protein
APY29_07190	ENOG4105CZX	twitching motility protein
APY29_07205	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
APY29_07215	ENOG4108UJU	UPF0301 protein
APY29_07220	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
APY29_07225	ENOG4105CXT	aspartate transcarbamylase
APY29_07230	ENOG4108Z9K	Osmotically inducible protein
APY29_07240	ENOG4105JAB	phenazine biosynthesis protein, phzf family
APY29_07245	ENOG4105JAB	phenazine biosynthesis protein, phzf family
APY29_07250	ENOG4105CFH	Aspartokinase
APY29_07265	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
APY29_07275	ENOG4105EAH	synthase
APY29_07280	ENOG4108UUM	single-stranded DNA-binding protein
APY29_07295	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
APY29_07300	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
APY29_07305	ENOG4105C7W	Xanthine dehydrogenase
APY29_07310	ENOG4107XAN	XdhC and CoxI family
APY29_07355	ENOG4105VCD	cytoplasmic protein
APY29_07360	ENOG4105D22	carbon starvation protein
APY29_07365	ENOG4105EUB	pirin domain protein
APY29_07380	ENOG4105EUB	pirin domain protein
APY29_07390	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
APY29_07395	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
APY29_07405	ENOG4105C9K	Endothelin-converting enzyme 1
APY29_07410	ENOG4107RZC	phospholipase d
APY29_07415	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
APY29_07420	ENOG4105BZU	Histidine kinase
APY29_07425	ENOG4105BZU	Histidine kinase
APY29_07430	ENOG4108V3W	Chemotaxis protein, CheW
APY29_07435	ENOG4105C8Q	Methyl-accepting chemotaxis
APY29_07440	ENOG4105CBS	Chea signal transduction histidine kinase
APY29_07470	ENOG4108JA2	transcriptioN-repair coupling factor
APY29_07480	ENOG4105D6S	protein involved in catabolism of external DNA
APY29_07485	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
APY29_07490	ENOG4105EB3	Histidine kinase
APY29_07505	ENOG4105CT7	inner membrane cred family protein
APY29_07530	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
APY29_07535	ENOG4105MYN	Zinc uptake regulation protein
APY29_07545	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
APY29_07550	ENOG4105BZS	acriflavin resistance protein
APY29_07555	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
APY29_07560	ENOG4108JGH	Tetr family transcriptional regulator
APY29_07565	ENOG4107SET	aldo keto reductase
APY29_07570	ENOG4105EQ2	LysR family Transcriptional regulator
APY29_07580	ENOG4105CF7	AraC family transcriptional regulator
APY29_07590	ENOG4105EJC	lysr family transcriptional regulator
APY29_07595	ENOG4105F27	Major Facilitator
APY29_07630	ENOG4105UGU	tonB-dependent Receptor
APY29_07650	ENOG4105CMQ	Chloride channel
APY29_07715	ENOG4105BZU	Histidine kinase
APY29_07720	ENOG4105FE9	pseudouridine synthase
APY29_07725	ENOG4105BZU	Histidine kinase
APY29_07745	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
APY29_07750	ENOG4105FQP	Beta-lactamase
APY29_07765	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
APY29_07770	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
APY29_07795	ENOG4105BZ1	(ABC) transporter
APY29_07835	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
APY29_07840	ENOG4105WG9	Conserved Protein
APY29_07880	ENOG4107QR8	Thioredoxin
APY29_07890	ENOG4105C8T	Leucyl-tRNA synthetase
APY29_07905	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
APY29_07920	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
APY29_07935	ENOG4105MPN	Membrane
APY29_07940	ENOG4108Z03	MAF-like protein
APY29_07945	ENOG4105C03	ribonuclease
APY29_07950	ENOG4105QD6	exported protein
APY29_07960	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
APY29_07965	ENOG4105N42	UPF0307 protein
APY29_07970	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
APY29_07990	ENOG4105MP0	transposase
APY29_07995	ENOG4105CTB	Polyprenyl synthetase
APY29_08000	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
APY29_08005	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
APY29_08015	ENOG4105G6Z	alkaline phosphatase
APY29_08020	ENOG4105CK2	sodium dicarboxylate symporter
APY29_08025	ENOG41082K6	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
APY29_08035	ENOG4105K4H	Nlp p60 protein
APY29_08040	ENOG4105K4H	Nlp p60 protein
APY29_08045	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
APY29_08055	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
APY29_08060	ENOG4105DC8	reductase
APY29_08080	ENOG4105C9K	Endothelin-converting enzyme 1
APY29_08085	ENOG4105C9K	Endothelin-converting enzyme 1
APY29_08110	ENOG4105DHP	deoxycytidine triphosphate deaminase
APY29_08170	ENOG4106A2Z	transcriptional regulator antitoxin, MazE
APY29_08180	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
APY29_08185	ENOG4108RRZ	Transcription elongation factor GreB
APY29_08200	ENOG4107VIJ	nudix hydrolase
APY29_08215	ENOG4105MP0	transposase
APY29_08225	ENOG4105DJ4	phosphatidylserine decarboxylase
APY29_08235	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
APY29_08240	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
APY29_08245	ENOG4105C5I	Dehydrogenase
APY29_08250	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
APY29_08270	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
APY29_08275	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
APY29_08285	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
APY29_08295	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
APY29_08300	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
APY29_08305	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
APY29_08325	ENOG4105BZU	Histidine kinase
APY29_08340	ENOG4107FW0	short-chain dehydrogenase reductase
APY29_08345	ENOG4105CP7	Triose-phosphate isomerase
APY29_08360	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
APY29_08365	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
APY29_08370	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
APY29_08375	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
APY29_08380	ENOG4105GKE	subunit e
APY29_08385	ENOG4107QIZ	NADH dehydrogenase
APY29_08390	ENOG4107R0R	NADH dehydrogenase subunit g
APY29_08395	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
APY29_08400	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
APY29_08405	ENOG4105DF2	NADH dehydrogenase subunit j
APY29_08415	ENOG4105D65	subunit l
APY29_08420	ENOG4105C8S	subunit m
APY29_08425	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
APY29_08435	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
APY29_08440	ENOG4105CHV	Transcription elongation factor NusA
APY29_08445	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
APY29_08450	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
APY29_08455	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
APY29_08460	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
APY29_08465	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
APY29_08475	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
APY29_08485	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
APY29_08490	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
APY29_08495	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
APY29_08500	ENOG4105M2J	Glutaredoxin
APY29_08510	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
APY29_08515	ENOG4108KPZ	tonB-dependent Receptor
APY29_08520	ENOG4105EWT	decarboxylase family
APY29_08560	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
APY29_08595	ENOG4105CMA	conjugation trbi family protein
APY29_08685	ENOG4107RBJ	symporter
APY29_08695	ENOG4105ETE	Transcriptional regulator (LacI family
APY29_08700	ENOG4105C22	threonyL-tRNA synthetase
APY29_08705	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
APY29_08710	ENOG41082NX	50s ribosomal protein l35
APY29_08715	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
APY29_08720	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
APY29_08725	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
APY29_08730	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
APY29_08735	ENOG4105WJX	transcriptional regulator MERR family
APY29_08755	ENOG4105D3Q	Sugar transferase
APY29_08780	ENOG4107Y2G	Glycosyl transferase (Group 1
APY29_08790	ENOG4108NQK	Catalyzes the transfer of a glucuronic acid (GlcA) residue from UDP-glucuronate to mannose-alpha-1,3-glucose-beta- 1,4-glucose-P-P-polyisoprenyl to form the lipid-linked tetrasaccharide GlcA-Man-Glc(2)-PP-Pol, with a glucuronic acid- beta-mannose linkage. Is involved in the biosynthesis of the exopolysaccharide xanthan, since it catalyzes the fourth glycosylation step in the assembly of the pentasaccharide-P-P- polyisoprenyl repeating unit of xanthan. Is unable to use the trisaccharide acceptor freed from the pyrophosphate lipid moiety. Does not show specificity for the lipidic portion of the acceptor. Shows diminished activity when tested with 6-O-acetyl-mannose- alpha-1,3-glucose-beta-1,4-glucose-P-P-polyisoprenyl, a
APY29_08815	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
APY29_08820	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
APY29_08825	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
APY29_08845	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
APY29_08855	ENOG4105CSU	acyl-Coa dehydrogenase
APY29_08865	ENOG4105QNF	Outer membrane lipoprotein
APY29_08880	ENOG4105DKD	Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity)
APY29_08895	ENOG4105CQZ	Histidine kinase
APY29_08900	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
APY29_08905	ENOG4105CEN	a g-specific adenine glycosylase
APY29_08910	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
APY29_08920	ENOG4105CTU	Proline racemase
APY29_08925	ENOG41080HI	glycine oxidase
APY29_08940	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
APY29_08950	ENOG4105DC7	peptidase M24
APY29_08965	ENOG4107QTZ	amino acid
APY29_09020	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
APY29_09055	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
APY29_09060	ENOG4106H78	methyltransferase
APY29_09065	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
APY29_09075	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
APY29_09080	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
APY29_09090	ENOG4105E08	Glycoside hydrolase, family 9
APY29_09095	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
APY29_09145	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
APY29_09150	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
APY29_09155	ENOG4105VIE	preprotein translocase, subunit YajC
APY29_09160	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
APY29_09165	ENOG4107QT7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
APY29_09220	ENOG4105DM4	PTS System
APY29_09225	ENOG4105DE4	1-phosphofructokinase
APY29_09230	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
APY29_09235	ENOG4108M60	Transcriptional regulator
APY29_09240	ENOG4105BZS	acriflavin resistance protein
APY29_09245	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
APY29_09255	ENOG4105C7I	Dehydrogenase
APY29_09260	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
APY29_09265	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
APY29_09270	ENOG4105BZU	Histidine kinase
APY29_09275	ENOG4106BRA	Membrane
APY29_09295	ENOG4105FCD	Major Facilitator
APY29_09300	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
APY29_09305	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
APY29_09315	ENOG4105CSH	Transporter
APY29_09320	ENOG4105W3S	hemerythrin-like, metal-binding protein
APY29_09325	ENOG4105BZU	Histidine kinase
APY29_09330	ENOG4105CJP	fad dependent oxidoreductase
APY29_09335	ENOG4105CFQ	glutamine synthetase
APY29_09350	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
APY29_09355	ENOG4107RUE	extracellular solute-binding protein family 1
APY29_09375	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
APY29_09380	ENOG4105F38	ABC transporter, permease
APY29_09385	ENOG4105D38	putrescine abc transporter
APY29_09410	ENOG4108JU5	Magnesium and cobalt efflux protein
APY29_09420	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
APY29_09430	ENOG4105C9A	Phoh family
APY29_09435	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
APY29_09450	ENOG4105E4C	Lytic transglycosylase catalytic
APY29_09455	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
APY29_09460	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
APY29_09465	ENOG4105EIX	cytochrome c1
APY29_09470	ENOG4107MKT	Stringent starvation protein a
APY29_09475	ENOG4105KB2	stringent starvation protein b
APY29_09490	ENOG4107QRT	dEAD DEAH box helicase
APY29_09495	ENOG4108VX5	3-methyladenine DNA glycosylase
APY29_09500	ENOG4105C8Q	Methyl-accepting chemotaxis
APY29_09505	ENOG4108V3W	Chemotaxis protein, CheW
APY29_09570	ENOG4105DQE	DNA ligase
APY29_09580	ENOG4105E6M	Sulphatase-modifying factor protein
APY29_09590	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
APY29_09595	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
APY29_09600	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
APY29_09605	ENOG4105K8N	protein family UPF0079, ATPase
APY29_09610	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
APY29_09615	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
APY29_09635	ENOG4105CHR	reductase
APY29_09640	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
APY29_09645	ENOG4105D0M	Protease HtpX homolog
APY29_09655	ENOG4105CBX	hi0933 family
APY29_09660	ENOG4108VWS	Yaeq family
APY29_09665	ENOG4105VEQ	Cold shock protein
APY29_09670	ENOG4108RXX	maleylacetoacetate isomerase
APY29_09680	ENOG4105CNG	UPF0061 protein
APY29_09685	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
APY29_09690	ENOG4105C1J	atp-dependent rna helicase
APY29_09695	ENOG4105C5H	ABC transporter
APY29_09710	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
APY29_09715	ENOG4105ECY	inositol monophosphatase
APY29_09730	ENOG4105BZU	Histidine kinase
APY29_09735	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
APY29_09740	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
APY29_09750	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
APY29_09755	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
APY29_09760	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
APY29_09775	ENOG4105CMM	transposase
APY29_09815	ENOG4107FQ9	ethanolamine ammonia-lyase
APY29_09820	ENOG4105CPD	ethanolamine ammonia-lyase
APY29_09840	ENOG4105CD3	dihydroorotase
APY29_09845	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
APY29_09855	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
APY29_09865	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
APY29_09870	ENOG4105C8N	cysteinyl-tRNA synthetase
APY29_09880	ENOG4105DBV	ornithine carbamoyltransferase
APY29_09885	ENOG4105CDH	Citrulline--aspartate ligase
APY29_09900	ENOG4105CAS	nag kinase
APY29_09910	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
APY29_09915	ENOG4105CH7	arginosuccinase
APY29_09930	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
APY29_09950	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
APY29_09955	ENOG4105C4M	(Ubiquinol oxidase) subunit I
APY29_09960	ENOG4108JJ9	ABC, transporter
APY29_09965	ENOG4108JJ8	(ABC) transporter
APY29_09985	ENOG4105KWW	Biogenesis protein
APY29_09995	ENOG4105DA4	cytochrome c-type biogenesis protein
APY29_10000	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
APY29_10010	ENOG41060IM	Heme exporter protein
APY29_10015	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
APY29_10020	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
APY29_10025	ENOG4105CHM	Aminotransferase
APY29_10045	ENOG4105FE9	pseudouridine synthase
APY29_10050	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
APY29_10055	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
APY29_10060	ENOG4105K9H	YciI-like protein
APY29_10090	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
APY29_10095	ENOG4105DRS	transport system, permease
APY29_10125	ENOG4105DWY	Agmatine deiminase
APY29_10135	ENOG4105YK5	50S ribosomal protein L36
APY29_10140	ENOG4105CAT	Cytidine monophosphate kinase
APY29_10145	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
APY29_10150	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
APY29_10160	ENOG4105CFV	Tetratricopeptide repeat protein
APY29_10165	ENOG4105ESV	Glycosyl transferase, family 4
APY29_10175	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
APY29_10180	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
APY29_10190	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
APY29_10195	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
APY29_10200	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
APY29_10205	ENOG4105DFP	Integrase
APY29_10245	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
APY29_10255	ENOG4107S5I	aldo keto reductase
APY29_10345	ENOG4105EVH	UPF0753 protein
APY29_10350	ENOG4105DND	Transcriptional regulator
APY29_10370	ENOG4105WH1	Two component transcriptional regulator luxr family
APY29_10385	ENOG4105CHJ	isochorismatase hydrolase
APY29_10395	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
APY29_10400	ENOG4108Z6B	deaminase
APY29_10405	ENOG4105KST	dependent repressor
APY29_10410	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
APY29_10430	ENOG4107SFI	Major Facilitator superfamily
APY29_10450	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
APY29_10470	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
APY29_10480	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
APY29_10505	ENOG4105BZM	domain protein
APY29_10510	ENOG4105BZU	Histidine kinase
APY29_10550	ENOG4105N7H	Cytochrome
APY29_10575	ENOG4105CMM	transposase
APY29_10585	ENOG4105BZS	acriflavin resistance protein
APY29_10590	ENOG4108UHU	Aldolase
APY29_10595	ENOG4105C01	Dihydroxy-acid dehydratase
APY29_10600	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
APY29_10605	ENOG4105CHC	glucokinase (EC 2.7.1.2)
APY29_10620	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
APY29_10625	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
APY29_10650	ENOG410681N	tpr repeat protein
APY29_10660	ENOG4105D60	lipoprotein releasing system transmembrane protein
APY29_10665	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
APY29_10675	ENOG4108EC8	DNA internalization-related competence protein ComEC
APY29_10690	ENOG4105BZ1	(ABC) transporter
APY29_10695	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
APY29_10700	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
APY29_10705	ENOG4105KJF	protein tyrosine phosphatase
APY29_10715	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
APY29_10720	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
APY29_10760	ENOG4107QKA	exodeoxyribonuclease V beta
APY29_10765	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
APY29_10830	ENOG4105MP0	transposase
APY29_10900	ENOG4106NZI	LysR family Transcriptional regulator
APY29_11025	ENOG4105F9F	transposase
APY29_11055	ENOG41080R2	UPF0102 protein
APY29_11090	ENOG4105NI8	Cytosine-specific methyltransferase
APY29_11095	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
APY29_11100	ENOG4107YH6	single-stranded DNA-binding protein
APY29_11135	ENOG4107QJE	Chromosome Partitioning Protein
APY29_11155	ENOG4105NI8	Cytosine-specific methyltransferase
APY29_11160	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
APY29_11250	ENOG4107QQG	Dehydrogenase
APY29_11260	ENOG4108V1T	peptidylprolyl cis-trans isomerase
APY29_11270	ENOG4105C72	UPF0176 protein
APY29_11280	ENOG4105C03	ribonuclease
APY29_11285	ENOG4105EI2	Pseudouridine synthase
APY29_11290	ENOG4108NST	exported protein
APY29_11295	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
APY29_11305	ENOG41090A4	Pterin carbinolamine dehydratase
APY29_11310	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
APY29_11320	ENOG4105RJZ	Transcriptional regulator
APY29_11360	ENOG4105MP0	transposase
APY29_11425	ENOG4105W39	Membrane
APY29_11455	ENOG4105DY9	regulatoR
APY29_11480	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
APY29_11490	ENOG4105MP0	transposase
APY29_11510	ENOG4108ZXC	Two component transcriptional regulator, luxr family
APY29_11535	ENOG4108N8X	transition metal ion binding
APY29_11555	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
APY29_11565	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
APY29_11570	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
APY29_11580	ENOG4105CGK	Exodeoxyribonuclease III
APY29_11600	ENOG4105MP0	transposase
APY29_11615	ENOG4105MP0	transposase
APY29_11720	ENOG4105XMH	SpoVT AbrB domain protein
APY29_11730	ENOG4105YES	addiction module antidote protein
APY29_11870	ENOG4105D06	uba thif-type nad fad binding protein
APY29_11875	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
APY29_11880	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
APY29_11885	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
APY29_11895	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
APY29_11905	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
APY29_11910	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
APY29_11925	ENOG4105CHU	acetyl-coa acetyltransferase
APY29_11930	ENOG41082MI	Protein CrcB homolog
APY29_11935	ENOG4105D1H	recombination factor protein RarA
APY29_11945	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
APY29_11955	ENOG4105CNU	cell division protein FtsK
APY29_11960	ENOG4105C3M	thioredoxin reductase
APY29_11970	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
APY29_11975	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
APY29_11980	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
APY29_11985	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
APY29_11995	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
APY29_12015	ENOG4105BZU	Histidine kinase
APY29_12025	ENOG4105BZU	Histidine kinase
APY29_12030	ENOG4105BZU	Histidine kinase
APY29_12050	ENOG4107R88	Chemotaxis protein (CheV)
APY29_12060	ENOG4108ZC9	flagellar basal-body rod protein flgc
APY29_12065	ENOG410822I	Flagellar hook capping protein
APY29_12070	ENOG4105BZE	flagellar hook protein, FlgE
APY29_12075	ENOG4108KPB	Flagellar basal-body rod protein FlgF
APY29_12080	ENOG4105CGA	flagellar basal-body rod protein FlgG
APY29_12085	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
APY29_12090	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
APY29_12095	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
APY29_12105	ENOG4105DTJ	flagellar hook-associated protein
APY29_12115	ENOG4107W9T	flagellar hook-associated
APY29_12120	ENOG4105MQ3	flagellar protein FliS
APY29_12140	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
APY29_12145	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
APY29_12150	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
APY29_12165	ENOG4108P1X	synthase
APY29_12170	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
APY29_12215	ENOG4105CMM	transposase
APY29_12220	ENOG4107RGC	Glycosyl transferase, family 2
APY29_12225	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
APY29_12230	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
APY29_12235	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
APY29_12245	ENOG4108JIR	Flagellum-specific ATP synthase
APY29_12265	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
APY29_12270	ENOG4105DD5	Flagellar motor switch protein
APY29_12275	ENOG4105K0P	flagellar biosynthesis protein
APY29_12280	ENOG4105CN7	Flagellar biosynthetic protein FliP
APY29_12285	ENOG4105VS8	Flagellar biosynthetic protein fliq
APY29_12290	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
APY29_12295	ENOG4105BZU	Histidine kinase
APY29_12305	ENOG4105BZU	Histidine kinase
APY29_12310	ENOG4105BZU	Histidine kinase
APY29_12315	ENOG4105D00	flagellar biosynthetic protein flhB
APY29_12320	ENOG4105D7B	Flagellar biosynthesis protein flha
APY29_12325	ENOG4105FZW	flagellar biosynthesis regulator FlhF
APY29_12330	ENOG4107R21	site-determining protein
APY29_12335	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
APY29_12340	ENOG4108VYJ	response regulator receiver protein
APY29_12350	ENOG4105CBS	Chea signal transduction histidine kinase
APY29_12375	ENOG4105CMM	transposase
APY29_12410	ENOG4105CMM	transposase
APY29_12425	ENOG4105E14	MotA TolQ exbB proton channel
APY29_12430	ENOG4105ER2	Ompa motb domain protein
APY29_12435	ENOG4107QJE	Chromosome Partitioning Protein
APY29_12440	ENOG4108V3W	Chemotaxis protein, CheW
APY29_12450	ENOG4108VYJ	response regulator receiver protein
APY29_12455	ENOG4105CBS	Chea signal transduction histidine kinase
APY29_12460	ENOG4105C8Q	Methyl-accepting chemotaxis
APY29_12470	ENOG4105C8Q	Methyl-accepting chemotaxis
APY29_12470	ENOG4105C8Q	Methyl-accepting chemotaxis
APY29_12475	ENOG4105C8Q	Methyl-accepting chemotaxis
APY29_12485	ENOG4105C8Q	Methyl-accepting chemotaxis
APY29_12495	ENOG4105C8Q	Methyl-accepting chemotaxis
APY29_12510	ENOG4105C8Q	Methyl-accepting chemotaxis
APY29_12515	ENOG4105C8Q	Methyl-accepting chemotaxis
APY29_12520	ENOG4105C8Q	Methyl-accepting chemotaxis
APY29_12525	ENOG4105C8Q	Methyl-accepting chemotaxis
APY29_12535	ENOG4108V3W	Chemotaxis protein, CheW
APY29_12545	ENOG4105C8Q	Methyl-accepting chemotaxis
APY29_12550	ENOG4105BZU	Histidine kinase
APY29_12555	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
APY29_12560	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
APY29_12565	ENOG4105BZU	Histidine kinase
APY29_12575	ENOG4107QIJ	Aconitate hydratase 2
APY29_12590	ENOG4107QM5	aconitate hydratase
APY29_12600	ENOG4105CEY	Amp-dependent synthetase and ligase
APY29_12605	ENOG4105E39	Enoyl-CoA hydratase
APY29_12610	ENOG4105BZU	Histidine kinase
APY29_12615	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
APY29_12620	ENOG4105CRK	lysyL-tRNA synthetase
APY29_12625	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
APY29_12630	ENOG4105DY9	regulatoR
APY29_12635	ENOG4105CMM	transposase
APY29_12675	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
APY29_12685	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
APY29_12690	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
APY29_12700	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
APY29_12705	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
APY29_12710	ENOG4108RPX	mosc domain containing protein
APY29_12715	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
APY29_12730	ENOG4105CE1	Ferrous iron transport protein b
APY29_12750	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
APY29_12760	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
APY29_12780	ENOG4105CQB	FAD linked oxidase domain protein
APY29_12785	ENOG4108JQ1	Dehydrogenase
APY29_12795	ENOG4105CUB	amino acid
APY29_12800	ENOG4105CUB	amino acid
APY29_12805	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
APY29_12810	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
APY29_12815	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
APY29_12830	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
APY29_12835	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
APY29_12840	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
APY29_12845	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
APY29_12850	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
APY29_12855	ENOG4105CIH	Imidazole acetol-phosphate transaminase
APY29_12860	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
APY29_12865	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
APY29_12875	ENOG4105CUT	histidyl-tRNA synthetase
APY29_12880	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
APY29_12890	ENOG4105D98	threonine synthase
APY29_12935	ENOG4107BJW	polysaccharide deacetylase
APY29_12940	ENOG4105CND	Glycosyl transferase, family 2
APY29_12955	ENOG4105C26	Dehydrogenase
APY29_12970	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
APY29_12975	ENOG4105D4A	Cell wall formation (By similarity)
APY29_12980	ENOG4108SXK	Transporter Drug Metabolite Exporter family
APY29_12995	ENOG410841Q	phosphoesterase PA-phosphatase related protein
APY29_13000	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
APY29_13010	ENOG4108UYB	regulatoR
APY29_13015	ENOG4105KU2	hydrolase family 5
APY29_13050	ENOG4107QP8	phosphohexose isomerase
APY29_13055	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
APY29_13060	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
APY29_13065	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
APY29_13070	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
APY29_13075	ENOG4105DJ0	Poly(A) Polymerase
APY29_13085	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
APY29_13090	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
APY29_13110	ENOG4105C93	Xylose Isomerase
APY29_13115	ENOG4105CMG	Carbohydrate kinase
APY29_13170	ENOG4108RTU	Aldolase
APY29_13175	ENOG4105CXK	mandelate racemase muconate lactonizing
APY29_13185	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
APY29_13190	ENOG4108Z4U	Ferredoxin
APY29_13200	ENOG4107TUS	Dihydrodipicolinate synthase
APY29_13215	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
APY29_13220	ENOG4108IAB	Phoh family
APY29_13260	ENOG4105CWB	LysR family transcriptional Regulator
APY29_13275	ENOG4107SDU	Methyl-accepting chemotaxis
APY29_13285	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
APY29_13290	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
APY29_13295	ENOG4105Y3E	Modulates RecA activity (By similarity)
APY29_13300	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
APY29_13305	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
APY29_13310	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
APY29_13315	ENOG4107TH8	cina domain protein
APY29_13320	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
APY29_13325	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
APY29_13330	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
APY29_13335	ENOG4105EEI	dihydropteroate synthase
APY29_13340	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
APY29_13345	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
APY29_13350	ENOG4105HBR	Rna-binding protein
APY29_13360	ENOG4108K5P	(LipO)protein
APY29_13365	ENOG4108UM1	dedA family
APY29_13370	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
APY29_13375	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
APY29_13380	ENOG4108DG9	Smr protein MutS2
APY29_13385	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
APY29_13390	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
APY29_13400	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
APY29_13405	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
APY29_13415	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
APY29_13420	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
APY29_13430	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
APY29_13445	ENOG4105CJ3	phosphate transporter
APY29_13470	ENOG4105DEN	Luciferase family
APY29_13475	ENOG41079KZ	Major Facilitator Superfamily
APY29_13480	ENOG4105BZ1	(ABC) transporter
APY29_13485	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
APY29_13510	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
APY29_13540	ENOG4105EGZ	biosynthesis protein
APY29_13615	ENOG4105CVE	Lytic murein transglycosylase
APY29_13655	ENOG4105EMN	RNA polymerase sigma factor
APY29_13670	ENOG41060IM	Heme exporter protein
APY29_13680	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
APY29_13685	ENOG4105DA4	cytochrome c-type biogenesis protein
APY29_13690	ENOG4107QX9	Thiol disulfide interChange protein
APY29_13695	ENOG4105KWW	Biogenesis protein
APY29_13715	ENOG4105BZU	Histidine kinase
APY29_13745	ENOG4105C8Q	Methyl-accepting chemotaxis
APY29_13760	ENOG4105CC0	LysR family Transcriptional regulator
APY29_13765	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
APY29_13770	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
APY29_13785	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
APY29_13795	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
APY29_13800	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
APY29_13805	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
APY29_13845	ENOG4105CI2	imidazolone-5-propionate hydrolase
APY29_13850	ENOG4105C84	Histidine ammonia-lyase
APY29_13860	ENOG4105CGP	Urocanate hydratase
APY29_13870	ENOG4105DZG	Dehydrogenase
APY29_13875	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
APY29_13880	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
APY29_13890	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
APY29_13895	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
APY29_13900	ENOG4105CIH	Imidazole acetol-phosphate transaminase
APY29_13915	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
APY29_13925	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
APY29_13930	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
APY29_13935	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
APY29_13940	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
APY29_13945	ENOG4105C5S	asparaginyl-tRNA synthetase
APY29_13990	ENOG4105WH1	Two component transcriptional regulator luxr family
APY29_14035	ENOG41077A9	carbonic anhydrase
APY29_14040	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
APY29_14050	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
APY29_14055	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
APY29_14060	ENOG4105CJB	Exodeoxyribonuclease I
APY29_14085	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
APY29_14090	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
APY29_14095	ENOG4105C5H	ABC transporter
APY29_14125	ENOG4105KHC	sulfurtransferase
APY29_14130	ENOG4105P8F	nudix hydrolase
APY29_14135	ENOG4108V1T	peptidylprolyl cis-trans isomerase
APY29_14140	ENOG4105E39	Enoyl-CoA hydratase
APY29_14150	ENOG4105CSM	endonuclease III
APY29_14155	ENOG4105CHH	sulfate transporter
APY29_14160	ENOG4107B2H	carbonic anhydrase
APY29_14180	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
APY29_14185	ENOG4105C8U	phosphate abc transporter
APY29_14190	ENOG4105E2Z	phosphate ABC transporter (Permease
APY29_14195	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
APY29_14200	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
APY29_14210	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
APY29_14225	ENOG4105C2N	RNA methyltransferase TrmH family group 3
APY29_14235	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
APY29_14250	ENOG4105C1G	acyl-Coa dehydrogenase
APY29_14260	ENOG4105C3R	Methionine synthase
APY29_14265	ENOG4105C3R	Methionine synthase
APY29_14275	ENOG4105D7K	pfkb domain protein
APY29_14285	ENOG4105ETE	Transcriptional regulator (LacI family
APY29_14300	ENOG41069P5	Protein slyX homolog
APY29_14305	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
APY29_14310	ENOG4108V1T	peptidylprolyl cis-trans isomerase
APY29_14325	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
APY29_14330	ENOG4105CZV	ABC transporter
APY29_14360	ENOG4105C37	(CBS) domain
APY29_14380	ENOG4105EZE	Cupin 4 family protein
APY29_14390	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
APY29_14395	ENOG4105C7S	Dehydrogenase
APY29_14405	ENOG4108URH	decarboxylase
APY29_14415	ENOG4105BZ1	(ABC) transporter
APY29_14420	ENOG4105C5Q	Transcriptional regulator
APY29_14450	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
APY29_14455	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
APY29_14460	ENOG4105CFG	Acts as a chaperone (By similarity)
APY29_14465	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
APY29_14470	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
APY29_14475	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
APY29_14480	ENOG41090R7	Ferric uptake
APY29_14485	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
APY29_14495	ENOG4108Z1B	Cyclase dehydrase
APY29_14500	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
APY29_14555	ENOG4106TD9	Diguanylate cyclase
APY29_14565	ENOG4105BZU	Histidine kinase
APY29_14600	ENOG4105CR8	Transcriptional regulator
APY29_14605	ENOG4105CDV	Ompa motb domain protein
APY29_14610	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
APY29_14615	ENOG4105CDU	Replicative dna helicase
APY29_14625	ENOG4105CAQ	asparagine synthetase
APY29_14635	ENOG4108K3A	Glutathione S-transferase
APY29_14645	ENOG4105C1G	acyl-Coa dehydrogenase
APY29_14665	ENOG4105F8V	Hydrolase, tatD family
APY29_14670	ENOG4105CUZ	uba thif-type nad fad binding protein
APY29_14685	ENOG4105VEQ	Cold shock protein
APY29_14715	ENOG4107GFK	fumarate
APY29_14725	ENOG4105DP0	ferredoxin-NADP reductase
APY29_14730	ENOG4108V06	Glutathione peroxidase
APY29_14735	ENOG4105DGW	oligopeptidase A
APY29_14765	ENOG4105DUX	Transporter
APY29_14785	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
APY29_14790	ENOG4105CW7	secretion protein, HlyD family
APY29_14810	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
APY29_14815	ENOG4105FQ6	thiopurine methyltransferase
APY29_14820	ENOG4108UWD	Iron-storage protein
APY29_14830	ENOG4108ESX	Receptor
APY29_14840	ENOG4105CAQ	asparagine synthetase
APY29_14845	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
APY29_14850	ENOG4105KUZ	arsenate reductase
APY29_14860	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
APY29_14865	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
APY29_14900	ENOG4105CE9	30S ribosomal protein S2
APY29_14905	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
APY29_14910	ENOG4105BZU	Histidine kinase
APY29_14915	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
APY29_14920	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
APY29_14925	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
APY29_14930	ENOG4105KNE	Phosphatidate cytidylyltransferase
APY29_14935	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
APY29_14940	ENOG4105DZP	Membrane-associated zinc metalloprotease
APY29_14955	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
APY29_14960	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
APY29_14965	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
APY29_14970	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
APY29_14975	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
APY29_14985	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
APY29_15000	ENOG4108YXA	Membrane
APY29_15050	ENOG4107QK5	Homocysteine s-methyltransferase
APY29_15055	ENOG4108IQI	permease
APY29_15060	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
APY29_15065	ENOG4105DA5	(ABC) transporter
APY29_15080	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
APY29_15090	ENOG4108R3D	Electron transport complex
APY29_15110	ENOG4105K6V	RNA polymerase
APY29_15135	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
APY29_15150	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
APY29_15155	ENOG4105M4H	endoribonuclease L-psp
APY29_15200	ENOG4105F27	Major Facilitator
APY29_15210	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
APY29_15220	ENOG4108YZY	peptidylprolyl cis-trans isomerase
APY29_15225	ENOG4105DFF	Rod shape-determining protein mreb
APY29_15245	ENOG4105KSC	Transcriptional regulator, TraR DksA family
APY29_15265	ENOG4105MP0	transposase
APY29_15270	ENOG4108VKG	metal-dependent hydrolase
APY29_15290	ENOG4105CHU	acetyl-coa acetyltransferase
APY29_15305	ENOG4105BZU	Histidine kinase
APY29_15320	ENOG4107T0X	DNA ligase
APY29_15330	ENOG4107T0X	DNA ligase
APY29_15335	ENOG4107QRT	dEAD DEAH box helicase
APY29_15345	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
APY29_15350	ENOG4105VEQ	Cold shock protein
APY29_15355	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
APY29_15360	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
APY29_15365	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
APY29_15370	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
APY29_15375	ENOG4108QDE	fad dependent oxidoreductase
APY29_15380	ENOG4107ZXU	DSBA oxidoreductase
APY29_15390	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
APY29_15400	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
APY29_15405	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
APY29_15410	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
APY29_15420	ENOG4105C3F	Signal peptidase i
APY29_15425	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
APY29_15430	ENOG4105C0H	protease
APY29_15440	ENOG4105EMN	RNA polymerase sigma factor
APY29_15445	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
APY29_15455	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
APY29_15460	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
APY29_15470	ENOG4105C1G	acyl-Coa dehydrogenase
APY29_15475	ENOG4105C26	Dehydrogenase
APY29_15490	ENOG4106FKC	arabinogalactan endo-1,4-beta-galactosidase
APY29_15495	ENOG4105CNT	hydrolase family 2
APY29_15540	ENOG4105CNA	YD repeat protein
APY29_15560	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
APY29_15570	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
APY29_15575	ENOG4105VEJ	Heat shock protein
APY29_15595	ENOG4107QJQ	Mate efflux family protein
APY29_15600	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
APY29_15605	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
APY29_15610	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
APY29_15615	ENOG4105K5M	30s ribosomal protein S16
APY29_15625	ENOG4107QWG	2-Nitropropane dioxygenase
APY29_15630	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
APY29_15635	ENOG4105CRE	cytochrome C
APY29_15645	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
APY29_15655	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
APY29_15675	ENOG4105BZU	Histidine kinase
APY29_15680	ENOG4105BZU	Histidine kinase
APY29_15685	ENOG4107Z5C	methylesterase
APY29_15690	ENOG4105BZU	Histidine kinase
APY29_15695	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
APY29_15720	ENOG4105BZU	Histidine kinase
APY29_15730	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
APY29_15735	ENOG4105FUA	antagonist
APY29_15740	ENOG4107MMM	Anti-sigma-factor antagonist
APY29_15750	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
APY29_15765	ENOG4105KAF	membrAne
APY29_15770	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
APY29_15780	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
APY29_15785	ENOG4105CCU	oxidase (Subunit III)
APY29_15790	ENOG4105BZ9	Cytochrome C oxidase, subunit I
APY29_15795	ENOG4105E2S	oxidase) subunit II
APY29_15845	ENOG4105MP0	transposase
APY29_15940	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
APY29_15945	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
APY29_15950	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
APY29_15955	ENOG4105DTN	riboflavin biosynthesis protein ribF
APY29_15960	ENOG4105CJR	Integral membrane protein (MviN
APY29_15965	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
APY29_15970	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
APY29_15975	ENOG4105K46	50S ribosomal protein l27
APY29_15980	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
APY29_15985	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
APY29_15990	ENOG4108TGP	Thioesterase superfamily protein
APY29_16005	ENOG4105C29	acyl-CoA thioesterase
APY29_16030	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
APY29_16040	ENOG4107SPG	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
APY29_16080	ENOG4105WH1	Two component transcriptional regulator luxr family
APY29_16085	ENOG4105BZU	Histidine kinase
APY29_16100	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
APY29_16105	ENOG4107QMS	site-determining protein
APY29_16110	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
APY29_16120	ENOG4105DHQ	Histidine kinase
APY29_16125	ENOG4105ETX	regulatoR
APY29_16140	ENOG4105DIJ	Phosphoethanolamine transferase
APY29_16155	ENOG4105C2C	drug resistance transporter, Bcr CflA
APY29_16160	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
APY29_16165	ENOG4105EBR	Carboxylesterase
APY29_16170	ENOG4105CV8	reductase
APY29_16210	ENOG4106AXJ	AraC family transcriptional regulator
APY29_16240	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
APY29_16255	ENOG4105EPD	Oligopeptide transporter, Opt family
APY29_16270	ENOG4105C0B	DNA polymerase III (alpha subunit)
APY29_16285	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
APY29_16320	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
APY29_16325	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
APY29_16330	ENOG4105C7W	Xanthine dehydrogenase
APY29_16370	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
APY29_16375	ENOG4105MP0	transposase
APY29_16385	ENOG4105CWX	Alpha-1,2-mannosidase
APY29_16390	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
APY29_16405	ENOG4107Z4K	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
APY29_16410	ENOG4105CVJ	phosphoglycerate mutase
APY29_16415	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
APY29_16430	ENOG4107QMH	DNA methylase
APY29_16440	ENOG4105ESI	atpase involved in dna repair
APY29_16445	ENOG4105C0D	helicase
APY29_16470	ENOG4108XFH	Transcriptional regulator
APY29_16475	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
APY29_16485	ENOG4105CD8	aminopeptidase N
APY29_16490	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
APY29_16500	ENOG4105EPW	hflc protein
APY29_16505	ENOG4107QJR	hflk protein
APY29_16510	ENOG4105M3Z	response regulator
APY29_16535	ENOG4108JQB	penicillin-binding protein 1C
APY29_16550	ENOG4105DN3	alpha-2-macroglobulin domain protein
APY29_16565	ENOG4105C7F	AcnD-accessory protein PrpF
APY29_16575	ENOG4108I0Z	Aconitate hydratase
APY29_16580	ENOG4105BZN	citrate synthase
APY29_16585	ENOG4105CR4	methylisocitrate lyase
APY29_16590	ENOG4108JU7	Transcriptional regulator
APY29_16610	ENOG4107QRG	dna polymerase iii
APY29_16615	ENOG4105HHA	aminodeoxychorismate lyase
APY29_16625	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
APY29_16630	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
APY29_16635	ENOG4105CHR	reductase
APY29_16640	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
APY29_16650	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
APY29_16655	ENOG4105VGS	50s ribosomal protein l32
APY29_16660	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
APY29_16665	ENOG4108UHJ	MAF-like protein
APY29_16675	ENOG41089I4	Inherit from COG: Glycosyl transferase, family 2
APY29_16685	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
APY29_16695	ENOG4105F8C	transglutaminase domain-containing protein
APY29_16705	ENOG4105K59	histidine triad (HIT) protein
APY29_16710	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
APY29_16715	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
APY29_16720	ENOG4107QMP	dna polymerase iii subunits gamma and tau
APY29_16730	ENOG4108ZAF	Molybdopterin
APY29_16735	ENOG4105M00	molybdopterin converting factor, subunit 1
APY29_16740	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
APY29_16750	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
APY29_16755	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
APY29_16760	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
APY29_16765	ENOG4105DKP	glycosyl transferase, family 9
APY29_16780	ENOG4108ZF3	Phosphatase
APY29_16785	ENOG4107RZZ	dna polymerase iii epsilon subunit
APY29_16790	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
APY29_16800	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
APY29_16810	ENOG4105EIN	peptidylprolyl cis-trans isomerase
APY29_16840	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
APY29_16845	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
APY29_16850	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
APY29_16860	ENOG4105BZU	Histidine kinase
APY29_16890	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
APY29_16900	ENOG4105VW4	glutaredoxin 3
APY29_16905	ENOG4105ERG	peptidase m48, ste24p
APY29_16910	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
APY29_16915	ENOG4105BZU	Histidine kinase
APY29_16920	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
APY29_16925	ENOG4105C9X	ppx gppa phosphatase
APY29_16935	ENOG4105EYK	Phosphatidylglycerophosphatase B
APY29_16940	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
APY29_16950	ENOG4108YP4	Metalloprotease, specifically cleaves on the N-terminal side of aspartyl, glutamyl and cysteic acid residues (By similarity)
APY29_16975	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
APY29_16990	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
APY29_16995	ENOG4105CVJ	phosphoglycerate mutase
APY29_17010	ENOG4105HSS	phospholipase C
APY29_17020	ENOG4105CPQ	Dehydrogenase
APY29_17030	ENOG4108IJ6	ABC transporter
APY29_17040	ENOG4108I5D	sulfate abc transporter
APY29_17045	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
APY29_17050	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
APY29_17060	ENOG4108R99	pseudouridine synthase
APY29_17070	ENOG4105CDV	Ompa motb domain protein
APY29_17075	ENOG4105CIS	alcohol dehydrogenase
APY29_17080	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
APY29_17090	ENOG4108K3A	Glutathione S-transferase
APY29_17095	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
APY29_17100	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
APY29_17125	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
APY29_17140	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
APY29_17145	ENOG4108ZT0	50S ribosomal protein l17
APY29_17150	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
APY29_17155	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
APY29_17160	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
APY29_17165	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
APY29_17170	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
APY29_17175	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
APY29_17185	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
APY29_17190	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
APY29_17195	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
APY29_17200	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
APY29_17205	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
APY29_17210	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
APY29_17215	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
APY29_17220	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
APY29_17225	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
APY29_17235	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
APY29_17240	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
APY29_17245	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
APY29_17250	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
APY29_17255	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
APY29_17260	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
APY29_17265	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
APY29_17270	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
APY29_17275	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
APY29_17280	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
APY29_17285	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
APY29_17290	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
APY29_17295	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
APY29_17300	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
APY29_17305	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
APY29_17310	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
APY29_17315	ENOG4108VZM	50s ribosomal protein L10
APY29_17320	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
APY29_17325	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
APY29_17330	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
APY29_17335	ENOG4105PM1	preprotein translocase subunit SecE
APY29_17345	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
APY29_17365	ENOG4105C3G	gtp-binding protein
APY29_17370	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
APY29_17375	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
APY29_17380	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
APY29_17390	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
APY29_17395	ENOG4105QVB	outer membrane lipoprotein LolB
APY29_17400	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
APY29_17405	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
APY29_17410	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
APY29_17420	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
APY29_17425	ENOG4105CSR	polyphosphate kinase 2
APY29_17440	ENOG4107QX9	Thiol disulfide interChange protein
APY29_17445	ENOG4107S2Z	UPF0761 membrane protein
APY29_17450	ENOG4105CS1	NAD(P)H quinone oxidoreductase
APY29_17470	ENOG4108Z66	YbaK ebsC protein
APY29_17475	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
APY29_17490	ENOG4105CM2	brancheD-chain amino acid aminotransferase
APY29_17505	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
APY29_17510	ENOG4105W8H	transhydrogenase (subunit alpha
APY29_17530	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
APY29_17560	ENOG4105C2M	dna polymerase I
APY29_17580	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
APY29_17595	ENOG4105C5Q	Transcriptional regulator
APY29_17600	ENOG4105NXH	GreA GreB family elongation factor
APY29_17605	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
APY29_17615	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
APY29_17625	ENOG4105WH1	Two component transcriptional regulator luxr family
APY29_17630	ENOG4105BZU	Histidine kinase
APY29_17635	ENOG4105BZU	Histidine kinase
APY29_17650	ENOG4105CX6	glutaminyL-tRNA synthetase
APY29_17660	ENOG4105DXC	membrane
APY29_17715	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
APY29_17725	ENOG4105CEY	Amp-dependent synthetase and ligase
APY29_17730	ENOG4105DDW	LysR family Transcriptional regulator
APY29_17765	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
APY29_17770	ENOG4105D0A	hydroxylase
APY29_17780	ENOG4108WBT	adenosyltransferase
APY29_17795	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
APY29_17800	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
APY29_17805	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
APY29_17810	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
APY29_17815	ENOG4105NWN	ApaG protein
APY29_17820	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
APY29_17840	ENOG4105DEF	Extracellular solute-binding protein, family 5
APY29_17865	ENOG4108UZX	fmn reductase
APY29_17870	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
APY29_17880	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
APY29_17885	ENOG4105D7T	ABC transporter
APY29_17890	ENOG4107T8P	acyl-Coa dehydrogenase
APY29_17895	ENOG4107SM7	Transcriptional regulator
APY29_17910	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
APY29_17915	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
APY29_17935	ENOG41080IJ	Diacylglycerol kinase
APY29_17950	ENOG4105ETX	regulatoR
APY29_17955	ENOG4108UJV	acyl-CoA thioesterase i
APY29_17960	ENOG4108I0Y	(ABC) transporter
APY29_17970	ENOG4105E2B	Taurine dioxygenase
APY29_17985	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
APY29_18005	ENOG4105D05	Receptor
APY29_18015	ENOG4105CPC	Aldo Keto reductase
APY29_18020	ENOG4105D9N	nucleoside
APY29_18025	ENOG4108RVA	ribokinase
APY29_18035	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
APY29_18040	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
APY29_18050	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
APY29_18055	ENOG4105D6F	Phosphatase
APY29_18085	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
APY29_18095	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
APY29_18100	ENOG4105DXX	methyltransferase
APY29_18165	ENOG4105SYT	Methylenetetrahydrofolate reductase
APY29_18175	ENOG4105M6F	mutator MutT protein
APY29_18180	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
APY29_18185	ENOG4105DR5	peptidase
APY29_18195	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
APY29_18200	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
APY29_18205	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
APY29_18210	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
APY29_18215	ENOG4105CPF	Cell wall formation (By similarity)
APY29_18220	ENOG4105DFU	Cell wall formation (By similarity)
APY29_18225	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
APY29_18235	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
APY29_18240	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
APY29_18245	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
APY29_18250	ENOG4105CJN	penicillin-binding protein
APY29_18255	ENOG4106932	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
APY29_18260	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
APY29_18265	ENOG4108V6E	Cell division protein mraZ
APY29_18290	ENOG41082RQ	UPF0102 protein
APY29_18295	ENOG4105S2T	inner membrane protein YbcI
APY29_18300	ENOG4105CQB	FAD linked oxidase domain protein
APY29_18310	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
APY29_18315	ENOG4105C08	Histidine kinase
APY29_18335	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
APY29_18340	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
APY29_18345	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
APY29_18365	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
APY29_18370	ENOG4107YIM	Involved in the transcription termination process (By similarity)
APY29_18375	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
APY29_18380	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
APY29_18405	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
APY29_18415	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
APY29_18420	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
APY29_18430	ENOG4105C5H	ABC transporter
APY29_18445	ENOG4105JAB	phenazine biosynthesis protein, phzf family
APY29_18450	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
APY29_18465	ENOG4108QBQ	Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione (By similarity)
APY29_18490	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
APY29_18495	ENOG4105JJR	Histidine kinase
APY29_18515	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
APY29_18520	ENOG4106RE7	Cytochrome
APY29_18530	ENOG4108Z33	Thiol disulfide Interchange Protein
APY29_18540	ENOG4105C94	Transporter
APY29_18545	ENOG4105C26	Dehydrogenase
APY29_18550	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
APY29_18555	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
APY29_18565	ENOG4105CE4	GlcNAc 6-P deacetylase
APY29_18570	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
APY29_18575	ENOG4105ETE	Transcriptional regulator (LacI family
APY29_18585	ENOG4105FDP	GntR family transcriptional regulator
APY29_18600	ENOG4105CNT	hydrolase family 2
APY29_18625	ENOG4108RTD	type II secretion system protein K
APY29_18635	ENOG4105X5Z	General secretion pathway protein I
APY29_18640	ENOG4105VWV	general secretion pathway protein h
APY29_18645	ENOG4108VAU	general secretion pathway protein G
APY29_18650	ENOG4105D7Q	type ii secretion system
APY29_18655	ENOG4107QHF	type ii secretion system protein e
APY29_18660	ENOG4105GVR	general secretion pathway protein D
APY29_18710	ENOG4105BZU	Histidine kinase
APY29_18720	ENOG4105BZU	Histidine kinase
APY29_18725	ENOG4105W4M	Transport-associated protein
APY29_18735	ENOG4108J5G	6-phosphogluconate dehydrogenase
APY29_18780	ENOG4105EGI	Transcriptional regulator
APY29_18790	ENOG4105CN1	protease
APY29_18795	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
APY29_18800	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
APY29_18815	ENOG4105DZ1	carboxypeptidase
APY29_18825	ENOG4105K6T	rare lipoprotein A
APY29_18830	ENOG4105CVE	Lytic murein transglycosylase
APY29_18840	ENOG4105CNI	cell division protein FtsW
APY29_18855	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
APY29_18860	ENOG4105DFF	Rod shape-determining protein mreb
APY29_18870	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
APY29_18895	ENOG4108Q1J	Extracellular solute-binding protein, family 3
APY29_18900	ENOG4105DZG	Dehydrogenase
APY29_18920	ENOG4105CD8	aminopeptidase N
APY29_18925	ENOG4105BZU	Histidine kinase
APY29_18930	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
APY29_18955	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
APY29_18960	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
APY29_18965	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
APY29_18975	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
APY29_18985	ENOG4105WD1	Membrane
APY29_19030	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
APY29_19035	ENOG4108NEV	two component transcriptional regulator, LytTR family
APY29_19040	ENOG4108HRK	Histidine kinase
APY29_19050	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
APY29_19065	ENOG4105BZU	Histidine kinase
APY29_19070	ENOG4105CHH	sulfate transporter
APY29_19075	ENOG4106R7G	Glycoside hydrolase family 5
APY29_19080	ENOG4105C8Q	Methyl-accepting chemotaxis
APY29_19120	ENOG4105E53	ec 3.2.1.28
APY29_19130	ENOG4105D7N	magnesium and cobalt transport protein CorA
APY29_19150	ENOG4105F87	Dehydratase
APY29_19155	ENOG4105DFI	Membrane
APY29_19175	ENOG4105BZU	Histidine kinase
APY29_19180	ENOG4107QS8	(LipO)protein
APY29_19190	ENOG4105C5Z	peptidase
APY29_19195	ENOG4105EYF	MMPL domain protein
APY29_19220	ENOG4105CHF	Glutathione S-transferase
APY29_19230	ENOG4105PDP	Short chain dehydrogenase
APY29_19245	ENOG4107GJV	short-chain dehydrogenase reductase
APY29_19285	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
APY29_19320	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
APY29_19325	ENOG4105DRR	Transcriptional regulator, GntR family
APY29_19335	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
APY29_19340	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
APY29_19345	ENOG41065ZS	Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme- A to the apo- acyl-carrier-protein of the malonate decarboxylase to yield holo- acyl-carrier-protein (By similarity)
APY29_19360	ENOG4105WSE	Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity)
APY29_19390	ENOG4108YYC	ycei family
APY29_19395	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
APY29_19415	ENOG4105EX9	Membrane
APY29_19420	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
APY29_19445	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
APY29_19460	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
APY29_19465	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
APY29_19470	ENOG4108K8S	endonuclease I
APY29_19475	ENOG4105E1F	short-chain dehydrogenase reductase
APY29_19485	ENOG4105VV6	START domain-containing protein
APY29_19500	ENOG4105VF7	tolerance protein
APY29_19505	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
APY29_19510	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
APY29_19515	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
APY29_19525	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
APY29_19545	ENOG4105MP0	transposase
APY29_19550	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
APY29_19575	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
APY29_19580	ENOG4108HPI	phosphatidate Cytidylyltransferase
APY29_19605	ENOG41077RS	Phosphatase
APY29_19610	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
APY29_19615	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
APY29_19620	ENOG4105DC1	bifunctional purine biosynthesis protein purh
APY29_19630	ENOG4105C12	Phosphoribosylglycinamide synthetase
APY29_19640	ENOG4105EM2	membrane
APY29_19655	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
APY29_19670	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
APY29_19690	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
APY29_19715	ENOG4105BZU	Histidine kinase
APY29_19720	ENOG4108UQY	Iron-storage protein
APY29_19730	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
APY29_19745	ENOG4108UJD	30S ribosomal protein S9
APY29_19750	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
APY29_19755	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
APY29_19765	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
APY29_19770	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
APY29_19780	ENOG4105DK0	Indole-3-glycerol phosphate synthase
APY29_19785	ENOG4108I0Q	anthranilate phosphoribosyltransferase
APY29_19795	ENOG4105DDQ	anthranilate synthase
APY29_19805	ENOG4105CRQ	synthase (Component I)
APY29_19810	ENOG4107TE5	Lipid kinase
APY29_19815	ENOG4105KD7	acetyltransferase
APY29_19830	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
APY29_19835	ENOG4105C8V	SAICAR synthetase
APY29_19855	ENOG4105NVB	glycoside hydrolase, family 19
APY29_19875	ENOG4105D65	subunit l
APY29_19880	ENOG4108ZE9	Monovalent cation H antiporter subunit C
APY29_19885	ENOG4107R4Z	monovalent cation h antiporter subunit d
APY29_19895	ENOG4105W4C	monovalent cation H antiporter subunit F
APY29_19900	ENOG4105KJM	monovalent cation h antiporter subunit g
APY29_19915	ENOG4105F1J	Homogentisate 1,2-dioxygenase
APY29_19920	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
APY29_19935	ENOG4105DUX	Transporter
APY29_19940	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
APY29_19950	ENOG4107RUY	(E1 component), alpha subunit
APY29_19955	ENOG4105CPP	Dehydrogenase, E1 component
APY29_19965	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
APY29_19970	ENOG4105C1J	atp-dependent rna helicase
APY29_19980	ENOG4105CHR	reductase
APY29_19985	ENOG4105BZS	acriflavin resistance protein
APY29_20020	ENOG4107ZQV	short-chain dehydrogenase reductase
APY29_20025	ENOG4105K4T	epimerase
APY29_20050	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
APY29_20055	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
APY29_20060	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
APY29_20065	ENOG4105BZU	Histidine kinase
APY29_20070	ENOG4105CKW	Inner membrane protein yedI
APY29_20080	ENOG4107RES	phosphoglycerol transferase I
APY29_20085	ENOG4105EGS	Mechanosensitive ion channel
APY29_20105	ENOG4105FTC	Lytic transglycosylase catalytic
APY29_20115	ENOG4105K44	type iii secretion
APY29_20120	ENOG4108TN6	type iii secretion
APY29_20130	ENOG4108JIR	Flagellum-specific ATP synthase
APY29_20145	ENOG4107Y59	type iii secretion
APY29_20165	ENOG4108HR8	type iii secretion
APY29_20185	ENOG4105VS8	Flagellar biosynthetic protein fliq
APY29_20230	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
APY29_20235	ENOG41081UC	Inherit from COG: Competence protein
APY29_20240	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
APY29_20245	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
APY29_20255	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
APY29_20260	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
APY29_20295	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
APY29_20300	ENOG4105MH3	Protein of unknown function (DUF2490)
APY29_20315	ENOG4107HP6	Transcriptional regulator
APY29_20325	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
APY29_20330	ENOG4105F2Z	3-oxoadipate enol-lactonase
APY29_20335	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
APY29_20340	ENOG4105EU7	Protocatechuate 3,4-dioxygenase, beta
APY29_20350	ENOG4105CHU	acetyl-coa acetyltransferase
APY29_20375	ENOG4105E98	transcriptional regulator DeoR family
APY29_20380	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
APY29_20385	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
APY29_20390	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
APY29_20400	ENOG4105MP0	transposase
APY29_20410	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
APY29_20440	ENOG4105CPI	Metal Dependent Phosphohydrolase
APY29_20445	ENOG4105D2S	major facilitator superfamily
APY29_20455	ENOG4108Z0R	Transferase
APY29_20475	ENOG4105C01	Dihydroxy-acid dehydratase
APY29_20510	ENOG4105MP0	transposase
APY29_20545	ENOG4105ECR	NmrA family
APY29_20565	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
APY29_20580	ENOG4108UZX	fmn reductase
APY29_20585	ENOG4105DZ2	Transcriptional regulator
APY29_20590	ENOG4105WPN	DNA integration recombination invertion protein
APY29_20605	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
APY29_20615	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
APY29_20620	ENOG4105EB3	Histidine kinase
APY29_20625	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
APY29_20645	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
APY29_20650	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
APY29_20665	ENOG4105D94	Major Facilitator Superfamily
APY29_20680	ENOG4105CMM	transposase
APY29_20695	ENOG4105F8V	Hydrolase, tatD family
APY29_20700	ENOG4105ETT	transcriptional Regulator, LysR family
APY29_20715	ENOG4105C7N	Xanthine uracil vitamin C permease
APY29_20725	ENOG4105DU0	nucleoside hydrolase
APY29_20735	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
APY29_20745	ENOG4107RTG	Major Facilitator superfamily
APY29_20750	ENOG4105EQ2	LysR family Transcriptional regulator
APY29_20760	ENOG4105C5R	Aminotransferase
APY29_20780	ENOG4105E1J	oxidoreductase
APY29_20785	ENOG4105VT2	5-hydroxyisourate hydrolase
APY29_20790	ENOG4108W15	Protein of unknown function (DUF1456)
APY29_20795	ENOG4105CQ7	ATP-dependent helicase
APY29_20805	ENOG4108KPZ	tonB-dependent Receptor
APY29_20810	ENOG4108R99	pseudouridine synthase
APY29_20825	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
APY29_20855	ENOG4108ZHJ	Organic hydroperoxide resistance protein
APY29_20860	ENOG4105K56	Transcriptional regulator
APY29_20865	ENOG4105D6Z	AFG1 family ATPase
APY29_20875	ENOG4108TZV	Membrane
APY29_20950	ENOG4105C1G	acyl-Coa dehydrogenase
APY29_20955	ENOG4107QX3	carboxylase
APY29_20985	ENOG4105BZU	Histidine kinase
APY29_20995	ENOG4107QP3	malate synthase g
APY29_21000	ENOG4105DUM	transcriptional regulator, lysR family
APY29_21035	ENOG4105DGW	oligopeptidase A
APY29_21040	ENOG4105D44	asparaginase
APY29_21050	ENOG4108YZN	class I peptide chain release factor
APY29_21060	ENOG4105DR9	pseudouridine synthase
APY29_21070	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
APY29_21080	ENOG4105CPF	Cell wall formation (By similarity)
APY29_21095	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
APY29_21100	ENOG410680H	amp-dependent synthetase and ligase
APY29_21105	ENOG4105PI0	Ferredoxin
APY29_21110	ENOG4108J2P	Alpha beta hydrolase fold
APY29_21120	ENOG4105E2T	synthase III
APY29_21135	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
APY29_21160	ENOG4108TQ9	Histidine kinase
APY29_21165	ENOG4105C7K	acetolactate synthase
APY29_21175	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
APY29_21180	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
APY29_21185	ENOG4107YZP	Rhodanese domain protein
APY29_21220	ENOG4105CHU	acetyl-coa acetyltransferase
APY29_21235	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
APY29_21240	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
APY29_21245	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
APY29_21250	ENOG4105CUX	Signal transduction histidine kinase
APY29_21255	ENOG4105BZU	Histidine kinase
APY29_21265	ENOG4105C5F	glutamine synthetase
APY29_21270	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
APY29_21280	ENOG4108V1U	phospholipid-binding protein
APY29_21305	ENOG4105KA0	thioesterase Superfamily protein
APY29_21310	ENOG4107RZC	phospholipase d
APY29_21320	ENOG4105M4E	phosphohistidine phosphatase, SixA
APY29_21325	ENOG4105D1F	ATP-binding protein
APY29_21380	ENOG4105E90	ABC transporter
APY29_21385	ENOG4108IJ8	ABC transporter
APY29_21400	ENOG4105DKW	ABC transporter
APY29_21410	ENOG4105D78	K07001 NTE family protein
APY29_21415	ENOG4105CNM	Receptor
APY29_21420	ENOG4108YXU	transcriptional regulator AsnC family
APY29_21425	ENOG4105MIR	Phenylalanine 4-monooxygenase
APY29_21440	ENOG4107TDE	lipolytic protein G-D-S-L family
APY29_21450	ENOG4105CHR	reductase
APY29_21455	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
APY29_21460	ENOG4105ETE	Transcriptional regulator (LacI family
APY29_21465	ENOG4105DSG	hydrolase family 43
APY29_21470	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
APY29_21480	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
APY29_21495	ENOG4105EBR	Carboxylesterase
APY29_21510	ENOG4105MA0	exported protein
APY29_21515	ENOG4105CFU	surface antigen
APY29_21520	ENOG4105D05	Receptor
APY29_21525	ENOG4107RDJ	Sulfotransferase
APY29_21535	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
APY29_21540	ENOG4107QHF	type ii secretion system protein e
APY29_21550	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
APY29_21560	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
APY29_21565	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
APY29_21580	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
APY29_21600	ENOG4105DH7	May be involved in recombination (By similarity)
APY29_21605	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
APY29_21610	ENOG4105C93	Xylose Isomerase
APY29_21615	ENOG4105ETE	Transcriptional regulator (LacI family
APY29_21620	ENOG4105D0H	Alpha-glucuronidase (EC 3.2.1.139)
APY29_21630	ENOG4105CXK	mandelate racemase muconate lactonizing
APY29_21645	ENOG4105DEI	Mannitol dehydrogenase
APY29_21685	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
APY29_21715	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
APY29_21720	ENOG4105CNT	hydrolase family 2
APY29_21725	ENOG4105D2H	Uronic isomerase
APY29_21755	ENOG4105CT4	transporter
APY29_21760	ENOG4105DT9	hydrolase family 43
APY29_21790	ENOG4105CMM	transposase
APY29_21830	ENOG4105E55	glycerol-3-phosphate acyltransferase
APY29_21840	ENOG4105ETE	Transcriptional regulator (LacI family
APY29_21860	ENOG4105QV4	Tryptophan halogenase
APY29_21865	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
APY29_21870	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
APY29_21875	ENOG4108YXG	UPF0502 protein
APY29_21885	ENOG4105KNA	-acetyltransferase
APY29_21890	ENOG4105C4R	Atp-dependent dna helicase
APY29_21895	ENOG4107104	thymidine kinase
APY29_21900	ENOG4105BZU	Histidine kinase
APY29_21905	ENOG4105DJ9	glucan biosynthesis protein
APY29_21915	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
APY29_21945	ENOG4105DKK	Benzoate
APY29_21965	ENOG4105DSB	aldose 1-epimerase
APY29_21975	ENOG4105K5B	UPF0225 protein
APY29_21980	ENOG4105EJ9	Membrane
APY29_22000	ENOG4105EUJ	GTP cyclohydrolase i
APY29_22010	ENOG4105ZQC	membrane protein AaeX
APY29_22015	ENOG4105Y49	secretion protein, HlyD family
APY29_22025	ENOG4105DR8	Membrane
APY29_22030	ENOG4105CSH	Transporter
APY29_22035	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
APY29_22080	ENOG4105MP0	transposase
APY29_22105	ENOG4105D3G	Pseudouridine synthase
APY29_22115	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
APY29_22150	ENOG4107QKA	exodeoxyribonuclease V beta
APY29_22155	ENOG4105DSY	exodeoxyribonuclease V, gamma
APY29_22170	ENOG4105DHJ	ABC, transporter
APY29_22175	ENOG4105CY3	ABC transporter, permease
APY29_22180	ENOG4107PE3	Mammalian cell entry related domain protein
APY29_22195	ENOG410903C	(LipO)protein
APY29_22205	ENOG4108V06	Glutathione peroxidase
APY29_22215	ENOG4107QSV	RmuC domain protein
APY29_22220	ENOG4105CIS	alcohol dehydrogenase
APY29_22225	ENOG4105SKE	transcriptional Regulator LysR family
APY29_22235	ENOG4108TGY	Glutathione S-transferase
APY29_22245	ENOG4105CUB	amino acid
APY29_22250	ENOG4105CWX	Alpha-1,2-mannosidase
APY29_22255	ENOG4105NRM	Membrane
APY29_22260	ENOG4105BZU	Histidine kinase
APY29_22280	ENOG4105DR4	Methyltransferase
APY29_22285	ENOG4105DU1	integral membrane protein, terc
APY29_22295	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
APY29_22310	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
APY29_22315	ENOG4108ZJ4	polysaccharide deacetylase
APY29_22325	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
APY29_22330	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
APY29_22390	ENOG4105XMH	SpoVT AbrB domain protein
APY29_22405	ENOG4105CVE	Lytic murein transglycosylase
APY29_22425	ENOG4108C33	Resolvase
APY29_22475	ENOG4105MP0	transposase
APY29_22560	ENOG4105MP0	transposase
APY29_22590	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
APY29_22665	ENOG4105MP0	transposase
APY29_22715	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase