locus-tag	class	description
APY30_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
APY30_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
APY30_00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
APY30_00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
APY30_00030	ENOG4108K0D	peptidase, M48
APY30_00060	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
APY30_00070	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
APY30_00110	ENOG4105W5Q	DNA repair protein (RadC
APY30_00130	ENOG4105MP0	transposase
APY30_00135	ENOG4105CMM	transposase
APY30_00195	ENOG4105CN1	protease
APY30_00200	ENOG41063SB	peptidase
APY30_00210	ENOG4107VAM	peptidase, m28
APY30_00240	ENOG4105DQ4	alcohol dehydrogenase
APY30_00245	ENOG4105BZ8	glutamate synthase
APY30_00250	ENOG4105CBC	glutamate synthase
APY30_00295	ENOG4105D3Q	Sugar transferase
APY30_00300	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
APY30_00310	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
APY30_00315	ENOG4107RA4	Glycosyl transferase (Group 1
APY30_00335	ENOG4105CAQ	asparagine synthetase
APY30_00350	ENOG4105CMR	udp-glucose 4-epimerase
APY30_00365	ENOG4105BZ1	(ABC) transporter
APY30_00395	ENOG4107W2Z	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) (By similarity)
APY30_00475	ENOG4108I5C	dEAD DEAH box helicase
APY30_00480	ENOG4108UT2	hemolysin iii
APY30_00495	ENOG4107FW0	short-chain dehydrogenase reductase
APY30_00500	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
APY30_00545	ENOG4105RKW	reductase (By
APY30_00550	ENOG4108M3R	transcriptional activator CadC
APY30_00570	ENOG4105WH1	Two component transcriptional regulator luxr family
APY30_00575	ENOG4105BZU	Histidine kinase
APY30_00585	ENOG4105DMF	Dehydrogenase
APY30_00640	ENOG41082W1	Cupin 2, conserved barrel domain protein
APY30_00650	ENOG4105CHB	tonB-dependent Receptor
APY30_00655	ENOG4105CGF	Aromatic amino acid aminotransferase
APY30_00660	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
APY30_00690	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
APY30_00740	ENOG4105K63	Thioredoxin
APY30_00790	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
APY30_00795	ENOG4105CG3	alpha amylase, catalytic region
APY30_00800	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
APY30_00840	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
APY30_00845	ENOG4105CT4	transporter
APY30_00850	ENOG4105E2V	Glycosyltransferase 36
APY30_00865	ENOG4105BZU	Histidine kinase
APY30_00870	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
APY30_00880	ENOG4108K2P	TRANSCRIPTIONal
APY30_00885	ENOG4105EDR	glucose galactose transporter
APY30_00890	ENOG4105QJH	Domain of unknown function (DUF718)
APY30_00895	ENOG4105DIA	mandelate racemase muconate lactonizing
APY30_00900	ENOG4105ERH	Fumarylacetoacetate hydrolase
APY30_00905	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
APY30_00955	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
APY30_00965	ENOG41062QD	Membrane
APY30_00970	ENOG4107QN1	sodium solute
APY30_00980	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
APY30_00990	ENOG4105E2R	ROK family
APY30_00995	ENOG4105CGK	Exodeoxyribonuclease III
APY30_01025	ENOG4105DGI	Alkaline phosphatase
APY30_01030	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
APY30_01050	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
APY30_01065	ENOG4105KDC	50s ribosomal protein l28
APY30_01070	ENOG4105W0E	50S ribosomal protein L33
APY30_01075	ENOG4105KHM	amidohydrolase 2
APY30_01085	ENOG4105JSC	dimethylmenaquinone methyltransferase
APY30_01090	ENOG4108KB2	LysR family Transcriptional regulator
APY30_01095	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
APY30_01110	ENOG4105C4R	Atp-dependent dna helicase
APY30_01145	ENOG4108WC9	type VI secretion system effector, hcp1 family
APY30_01170	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
APY30_01195	ENOG4105D6F	Phosphatase
APY30_01235	ENOG4105CS6	Rhs element vgr protein
APY30_01270	ENOG4108ZF3	Phosphatase
APY30_01275	ENOG4107TPY	serine threonine protein kinase
APY30_01305	ENOG4105C2M	dna polymerase I
APY30_01315	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
APY30_01330	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
APY30_01355	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
APY30_01365	ENOG4105E9Q	Acyl-transferase
APY30_01370	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
APY30_01425	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
APY30_01435	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
APY30_01455	ENOG4105BZP	glycoside hydrolase 15-related
APY30_01460	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
APY30_01475	ENOG4105CJW	magnesium transporter
APY30_01480	ENOG4105CD5	CoA-binding domain protein
APY30_01490	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
APY30_01495	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
APY30_01525	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
APY30_01535	ENOG4105E3A	(ABC) transporter
APY30_01540	ENOG4105DA5	(ABC) transporter
APY30_01545	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
APY30_01550	ENOG4105ECQ	AraC Family Transcriptional Regulator
APY30_01560	ENOG4105E0K	tonB-dependent siderophore receptor
APY30_01570	ENOG4105PGM	cation diffusion facilitator family transporter
APY30_01590	ENOG4105VZ8	Transcriptional regulator
APY30_01600	ENOG4108IUW	ABC transporter
APY30_01615	ENOG4105QV4	Tryptophan halogenase
APY30_01640	ENOG4105CYM	Glutathione S-transferase
APY30_01685	ENOG4105D52	delta-aminolevulinic acid dehydratase
APY30_01705	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
APY30_01715	ENOG4105E2X	shikimate dehydrogenase
APY30_01730	ENOG4105DVT	helicase
APY30_01735	ENOG4105CH6	catalase
APY30_01750	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
APY30_01760	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
APY30_01765	ENOG4105EB3	Histidine kinase
APY30_01790	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
APY30_01870	ENOG4105VDW	Csbd family
APY30_01875	ENOG4105C31	Tryptophanyl-tRNA synthetase
APY30_01880	ENOG4108NNI	Beta-lactamase domain-containing protein
APY30_01895	ENOG4105FDR	Membrane
APY30_01920	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
APY30_01925	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
APY30_01930	ENOG4108ZGX	Histidine kinase
APY30_01935	ENOG4108S01	response regulator
APY30_01950	ENOG4107VGR	Catalase
APY30_01965	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
APY30_01970	ENOG4107URF	beta-phospho-glucomutase
APY30_01975	ENOG4105DSF	transport protein
APY30_01995	ENOG4105C0H	protease
APY30_02015	ENOG4105DHQ	Histidine kinase
APY30_02020	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
APY30_02025	ENOG4105ECP	epimerase
APY30_02065	ENOG4105E0Y	RtcB Protein
APY30_02085	ENOG4105EJ2	Transcriptional regulator
APY30_02100	ENOG41066DG	(EAL) domain protein
APY30_02115	ENOG4105C0P	Mg chelatase subunit ChlI
APY30_02120	ENOG4105W0Z	cytoplasmic protein
APY30_02125	ENOG4108YZA	Nitrogen regulatory protein pii
APY30_02155	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
APY30_02160	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
APY30_02165	ENOG4105CEY	Amp-dependent synthetase and ligase
APY30_02180	ENOG4105EMU	Dehydrogenase
APY30_02195	ENOG4105C75	arginyL-tRNA synthetase
APY30_02200	ENOG4105W5Q	DNA repair protein (RadC
APY30_02205	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
APY30_02210	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
APY30_02230	ENOG4105CKK	Glycosyl transferase, family 2
APY30_02245	ENOG4105FA0	parb-like partition protein
APY30_02250	ENOG4107QJE	Chromosome Partitioning Protein
APY30_02260	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
APY30_02265	ENOG4105CGK	Exodeoxyribonuclease III
APY30_02270	ENOG4105EYM	Major Facilitator superfamily
APY30_02280	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
APY30_02285	ENOG4105DR5	peptidase
APY30_02290	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
APY30_02325	ENOG4105C26	Dehydrogenase
APY30_02335	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
APY30_02345	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
APY30_02350	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
APY30_02375	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
APY30_02385	ENOG4105DHU	Bile acid
APY30_02390	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
APY30_02395	ENOG4107S2Z	UPF0761 membrane protein
APY30_02400	ENOG4105KTH	gatB Yqey
APY30_02405	ENOG4105VCC	30S ribosomal protein S21
APY30_02410	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
APY30_02415	ENOG4107ZVW	dihydroneopterin aldolase
APY30_02420	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
APY30_02430	ENOG4108Z12	YiaAB two helix domain-containing protein
APY30_02445	ENOG4105D5Q	Arginine ornithine antiporter
APY30_02455	ENOG4105DTQ	mandelate racemase muconate lactonizing
APY30_02465	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
APY30_02470	ENOG4108UQS	dipeptidase
APY30_02510	ENOG4105E32	cytoplasmic protein
APY30_02520	ENOG4105BZS	acriflavin resistance protein
APY30_02525	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
APY30_02530	ENOG4105CH2	amidohydrolase
APY30_02535	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
APY30_02550	ENOG4105E9K	Isocitrate dehydrogenase
APY30_02560	ENOG4105ETT	transcriptional Regulator, LysR family
APY30_02565	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
APY30_02575	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
APY30_02580	ENOG4105K63	Thioredoxin
APY30_02585	ENOG4105C1J	atp-dependent rna helicase
APY30_02590	ENOG4105CAK	Cell division ATP-binding protein ftsE
APY30_02595	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
APY30_02600	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
APY30_02605	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
APY30_02610	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
APY30_02615	ENOG4105EN6	Membrane
APY30_02635	ENOG4108TGY	Glutathione S-transferase
APY30_02640	ENOG4105C25	Primosomal protein n'
APY30_02660	ENOG4107QI1	Mate efflux family protein
APY30_02665	ENOG4105D07	Signal peptide peptidase, SppA
APY30_02675	ENOG4107ZQV	short-chain dehydrogenase reductase
APY30_02690	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
APY30_02695	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
APY30_02710	ENOG4108RPN	Protein smg homolog
APY30_02715	ENOG4105C79	DNA protecting protein DprA
APY30_02720	ENOG4108WZM	domain protein
APY30_02725	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
APY30_02730	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
APY30_02735	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
APY30_02780	ENOG4108Z7F	N-acetyltransferase
APY30_02785	ENOG4105D1S	lipid A biosynthesis
APY30_02790	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
APY30_02795	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
APY30_02845	ENOG4105C0D	helicase
APY30_02920	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
APY30_02925	ENOG4105HEI	LysR family (Transcriptional regulator
APY30_02945	ENOG4105CIG	ABC transporter
APY30_03005	ENOG4105E2A	Dehydrogenase
APY30_03020	ENOG4105BZ1	(ABC) transporter
APY30_03040	ENOG4105CMR	udp-glucose 4-epimerase
APY30_03045	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
APY30_03060	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
APY30_03065	ENOG4105C4M	(Ubiquinol oxidase) subunit I
APY30_03075	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
APY30_03110	ENOG4105WEF	catalase
APY30_03115	ENOG4108Z9Z	response to DNA damage stimulus
APY30_03125	ENOG4105MP0	transposase
APY30_03140	ENOG4105C2F	Histidine kinase
APY30_03145	ENOG4108VAC	response regulator
APY30_03155	ENOG4107QTZ	amino acid
APY30_03175	ENOG4105C9K	Endothelin-converting enzyme 1
APY30_03185	ENOG4105CPC	Aldo Keto reductase
APY30_03195	ENOG4105CBN	LysR family transcriptional regulator
APY30_03205	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
APY30_03215	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
APY30_03225	ENOG4105EEQ	Na H antiporter
APY30_03230	ENOG4105DA5	(ABC) transporter
APY30_03235	ENOG4105E3A	(ABC) transporter
APY30_03260	ENOG4105ER2	Ompa motb domain protein
APY30_03265	ENOG4107RD7	Flagellar Motor Protein, MotA
APY30_03285	ENOG4105EW9	transcriptional regulator AsnC family
APY30_03290	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
APY30_03295	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
APY30_03315	ENOG4105BZU	Histidine kinase
APY30_03340	ENOG4105I08	Pseudouridine synthase
APY30_03345	ENOG4107YBY	Hydrolase
APY30_03350	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
APY30_03370	ENOG4105BZU	Histidine kinase
APY30_03380	ENOG4108VPT	UPF0234 protein
APY30_03385	ENOG4108EHX	EamA-like transporter family
APY30_03390	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
APY30_03395	ENOG4108UMI	ABC transporter, permease
APY30_03400	ENOG4105D01	(LipO)protein
APY30_03445	ENOG4107QSN	dihydrolipoamide acetyltransferase
APY30_03455	ENOG4107QN2	dihydrolipoyl dehydrogenase
APY30_03475	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
APY30_03480	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
APY30_03485	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
APY30_03490	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
APY30_03495	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
APY30_03500	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
APY30_03505	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
APY30_03510	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
APY30_03525	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
APY30_03530	ENOG4105BZU	Histidine kinase
APY30_03535	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
APY30_03545	ENOG4107RBB	ABC transporter, permease
APY30_03550	ENOG4107RBB	ABC transporter, permease
APY30_03555	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
APY30_03560	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
APY30_03565	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
APY30_03600	ENOG4105E3B	Multicopper oxidase
APY30_03615	ENOG4105DGW	oligopeptidase A
APY30_03630	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
APY30_03635	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
APY30_03640	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
APY30_03645	ENOG4107RNH	Outer membrane receptor FepA
APY30_03650	ENOG4105NIV	Esterase
APY30_03665	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
APY30_03675	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
APY30_03680	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
APY30_03690	ENOG4105C1J	atp-dependent rna helicase
APY30_03700	ENOG4108RXX	maleylacetoacetate isomerase
APY30_03705	ENOG4105CZX	twitching motility protein
APY30_03730	ENOG4105C28	cystathionine
APY30_03740	ENOG4107STW	synthase
APY30_03750	ENOG4105EY8	ABC transporter
APY30_03760	ENOG4105CGN	Glycosyl transferase (Group 1
APY30_03765	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
APY30_03770	ENOG4108DMA	Nad-dependent epimerase dehydratase
APY30_03820	ENOG4105C10	Electron transfer flavoprotein
APY30_03825	ENOG4105BZJ	Electron transfer flavoprotein
APY30_03840	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
APY30_03845	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
APY30_03855	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
APY30_03860	ENOG4107QKV	phosphomannomutase
APY30_03875	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
APY30_03890	ENOG4108SNX	Mammalian cell entry related domain protein
APY30_03895	ENOG4105DHJ	ABC, transporter
APY30_03910	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
APY30_03915	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
APY30_03925	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
APY30_03955	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
APY30_03970	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
APY30_03980	ENOG4108K5H	permease YjgP YjgQ family protein
APY30_03995	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
APY30_04000	ENOG4105T95	Thiol disulfide interChange protein
APY30_04005	ENOG4108ETH	Formylglycinamide ribotide synthetase
APY30_04010	ENOG4105EUR	Domain-Containing protein
APY30_04015	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
APY30_04020	ENOG4105EUR	Domain-Containing protein
APY30_04025	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
APY30_04030	ENOG4107QHF	type ii secretion system protein e
APY30_04035	ENOG4105D7Q	type ii secretion system
APY30_04045	ENOG4105WMT	general secretion pathway protein h
APY30_04055	ENOG41069G9	General secretion pathway protein J
APY30_04060	ENOG4105UV2	general secretion pathway protein K
APY30_04065	ENOG41090VX	general secretion pathway protein L
APY30_04070	ENOG410678M	general secretion pathway protein M
APY30_04080	ENOG4105GVR	general secretion pathway protein D
APY30_04090	ENOG4105CMM	transposase
APY30_04100	ENOG4106S9K	Transcriptional regulator
APY30_04150	ENOG4107RH7	Nicotinate phosphoribosyltransferase
APY30_04165	ENOG4107QZ7	Cellulose synthase catalytic subunit
APY30_04170	ENOG4107EEX	Cellulose synthase regulator protein
APY30_04175	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
APY30_04180	ENOG4105EJG	cellulose synthase
APY30_04205	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
APY30_04210	ENOG4108RMV	DegV Family
APY30_04230	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
APY30_04235	ENOG41069H0	dihydroorotase EC 3.5.2.3
APY30_04260	ENOG4105CNM	Receptor
APY30_04280	ENOG4108JJA	ABC, transporter
APY30_04300	ENOG4105CMM	transposase
APY30_04395	ENOG4105DXC	membrane
APY30_04405	ENOG4105CX6	glutaminyL-tRNA synthetase
APY30_04420	ENOG4105BZU	Histidine kinase
APY30_04425	ENOG4105BZU	Histidine kinase
APY30_04430	ENOG4105WH1	Two component transcriptional regulator luxr family
APY30_04440	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
APY30_04450	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
APY30_04455	ENOG4105NXH	GreA GreB family elongation factor
APY30_04460	ENOG4105C5Q	Transcriptional regulator
APY30_04475	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
APY30_04495	ENOG4105C2M	dna polymerase I
APY30_04525	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
APY30_04545	ENOG4105W8H	transhydrogenase (subunit alpha
APY30_04550	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
APY30_04565	ENOG4105CM2	brancheD-chain amino acid aminotransferase
APY30_04580	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
APY30_04585	ENOG4108Z66	YbaK ebsC protein
APY30_04605	ENOG4105CS1	NAD(P)H quinone oxidoreductase
APY30_04610	ENOG4107S2Z	UPF0761 membrane protein
APY30_04615	ENOG4107QX9	Thiol disulfide interChange protein
APY30_04630	ENOG4105CSR	polyphosphate kinase 2
APY30_04635	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
APY30_04645	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
APY30_04650	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
APY30_04655	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
APY30_04660	ENOG4105QVB	outer membrane lipoprotein LolB
APY30_04665	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
APY30_04675	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
APY30_04680	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
APY30_04685	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
APY30_04690	ENOG4105C3G	gtp-binding protein
APY30_04710	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
APY30_04720	ENOG4105PM1	preprotein translocase subunit SecE
APY30_04725	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
APY30_04730	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
APY30_04735	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
APY30_04740	ENOG4108VZM	50s ribosomal protein L10
APY30_04745	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
APY30_04750	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
APY30_04755	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
APY30_04760	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
APY30_04765	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
APY30_04770	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
APY30_04775	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
APY30_04780	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
APY30_04785	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
APY30_04790	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
APY30_04795	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
APY30_04800	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
APY30_04805	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
APY30_04810	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
APY30_04815	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
APY30_04820	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
APY30_04830	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
APY30_04835	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
APY30_04840	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
APY30_04845	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
APY30_04850	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
APY30_04855	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
APY30_04860	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
APY30_04865	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
APY30_04870	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
APY30_04880	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
APY30_04885	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
APY30_04890	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
APY30_04895	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
APY30_04900	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
APY30_04905	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
APY30_04910	ENOG4108ZT0	50S ribosomal protein l17
APY30_04915	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
APY30_04930	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
APY30_04955	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
APY30_04960	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
APY30_04965	ENOG4108K3A	Glutathione S-transferase
APY30_04975	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
APY30_04980	ENOG4105CIS	alcohol dehydrogenase
APY30_04985	ENOG4105CDV	Ompa motb domain protein
APY30_04995	ENOG4108R99	pseudouridine synthase
APY30_05005	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
APY30_05010	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
APY30_05015	ENOG4108I5D	sulfate abc transporter
APY30_05025	ENOG4108IJ6	ABC transporter
APY30_05035	ENOG4105CPQ	Dehydrogenase
APY30_05045	ENOG4105HSS	phospholipase C
APY30_05060	ENOG4105CVJ	phosphoglycerate mutase
APY30_05065	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
APY30_05080	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
APY30_05105	ENOG4108YP4	Metalloprotease, specifically cleaves on the N-terminal side of aspartyl, glutamyl and cysteic acid residues (By similarity)
APY30_05115	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
APY30_05120	ENOG4105EYK	Phosphatidylglycerophosphatase B
APY30_05130	ENOG4105C9X	ppx gppa phosphatase
APY30_05135	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
APY30_05140	ENOG4105BZU	Histidine kinase
APY30_05145	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
APY30_05150	ENOG4105ERG	peptidase m48, ste24p
APY30_05155	ENOG4105VW4	glutaredoxin 3
APY30_05165	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
APY30_05205	ENOG4105MP0	transposase
APY30_05245	ENOG4105NVB	glycoside hydrolase, family 19
APY30_05290	ENOG4105ED4	portal protein
APY30_05310	ENOG4105BZU	Histidine kinase
APY30_05320	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
APY30_05325	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
APY30_05330	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
APY30_05360	ENOG4105EIN	peptidylprolyl cis-trans isomerase
APY30_05370	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
APY30_05380	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
APY30_05385	ENOG4107RZZ	dna polymerase iii epsilon subunit
APY30_05390	ENOG4108ZF3	Phosphatase
APY30_05405	ENOG4105DKP	glycosyl transferase, family 9
APY30_05410	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
APY30_05415	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
APY30_05420	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
APY30_05430	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
APY30_05435	ENOG4105M00	molybdopterin converting factor, subunit 1
APY30_05440	ENOG4108ZAF	Molybdopterin
APY30_05450	ENOG4107QMP	dna polymerase iii subunits gamma and tau
APY30_05455	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
APY30_05460	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
APY30_05465	ENOG4105K59	histidine triad (HIT) protein
APY30_05475	ENOG4105F8C	transglutaminase domain-containing protein
APY30_05485	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
APY30_05495	ENOG41089I4	Inherit from COG: Glycosyl transferase, family 2
APY30_05505	ENOG4108UHJ	MAF-like protein
APY30_05510	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
APY30_05515	ENOG4105VGS	50s ribosomal protein l32
APY30_05520	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
APY30_05530	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
APY30_05535	ENOG4105CHR	reductase
APY30_05540	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
APY30_05545	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
APY30_05555	ENOG4105HHA	aminodeoxychorismate lyase
APY30_05560	ENOG4107QRG	dna polymerase iii
APY30_05580	ENOG4108JU7	Transcriptional regulator
APY30_05585	ENOG4105CR4	methylisocitrate lyase
APY30_05590	ENOG4105BZN	citrate synthase
APY30_05595	ENOG4108I0Z	Aconitate hydratase
APY30_05605	ENOG4105C7F	AcnD-accessory protein PrpF
APY30_05620	ENOG4105DN3	alpha-2-macroglobulin domain protein
APY30_05635	ENOG4108JQB	penicillin-binding protein 1C
APY30_05660	ENOG4105M3Z	response regulator
APY30_05665	ENOG4107QJR	hflk protein
APY30_05670	ENOG4105EPW	hflc protein
APY30_05680	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
APY30_05685	ENOG4105CD8	aminopeptidase N
APY30_05695	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
APY30_05700	ENOG4108XFH	Transcriptional regulator
APY30_05725	ENOG4105C0D	helicase
APY30_05730	ENOG4105ESI	atpase involved in dna repair
APY30_05740	ENOG4107QMH	DNA methylase
APY30_05755	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
APY30_05760	ENOG4105CVJ	phosphoglycerate mutase
APY30_05765	ENOG4107Z4K	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
APY30_05780	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
APY30_05785	ENOG4105CWX	Alpha-1,2-mannosidase
APY30_05790	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
APY30_05800	ENOG4105C3M	thioredoxin reductase
APY30_05830	ENOG4105C7W	Xanthine dehydrogenase
APY30_05835	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
APY30_05840	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
APY30_05875	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
APY30_05890	ENOG4105C0B	DNA polymerase III (alpha subunit)
APY30_05905	ENOG4105EPD	Oligopeptide transporter, Opt family
APY30_05920	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
APY30_05950	ENOG4106AXJ	AraC family transcriptional regulator
APY30_05990	ENOG4105CV8	reductase
APY30_05995	ENOG4105EBR	Carboxylesterase
APY30_06000	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
APY30_06005	ENOG4105C2C	drug resistance transporter, Bcr CflA
APY30_06020	ENOG4105DIJ	Phosphoethanolamine transferase
APY30_06035	ENOG4105ETX	regulatoR
APY30_06040	ENOG4105DHQ	Histidine kinase
APY30_06050	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
APY30_06055	ENOG4107QMS	site-determining protein
APY30_06060	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
APY30_06070	ENOG4105BZU	Histidine kinase
APY30_06075	ENOG4105WH1	Two component transcriptional regulator luxr family
APY30_06115	ENOG4107SPG	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
APY30_06125	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
APY30_06150	ENOG4105C29	acyl-CoA thioesterase
APY30_06165	ENOG4108TGP	Thioesterase superfamily protein
APY30_06170	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
APY30_06175	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
APY30_06180	ENOG4105K46	50S ribosomal protein l27
APY30_06185	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
APY30_06190	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
APY30_06195	ENOG4105CJR	Integral membrane protein (MviN
APY30_06200	ENOG4105DTN	riboflavin biosynthesis protein ribF
APY30_06205	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
APY30_06210	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
APY30_06215	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
APY30_06225	ENOG4105E2S	oxidase) subunit II
APY30_06230	ENOG4105BZ9	Cytochrome C oxidase, subunit I
APY30_06235	ENOG4105CCU	oxidase (Subunit III)
APY30_06240	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
APY30_06250	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
APY30_06255	ENOG4105KAF	membrAne
APY30_06270	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
APY30_06280	ENOG4107MMM	Anti-sigma-factor antagonist
APY30_06285	ENOG4105FUA	antagonist
APY30_06290	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
APY30_06300	ENOG4105BZU	Histidine kinase
APY30_06325	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
APY30_06330	ENOG4105BZU	Histidine kinase
APY30_06335	ENOG4107Z5C	methylesterase
APY30_06340	ENOG4105BZU	Histidine kinase
APY30_06345	ENOG4105BZU	Histidine kinase
APY30_06365	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
APY30_06375	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
APY30_06385	ENOG4105CRE	cytochrome C
APY30_06390	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
APY30_06395	ENOG4107QWG	2-Nitropropane dioxygenase
APY30_06405	ENOG4105K5M	30s ribosomal protein S16
APY30_06410	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
APY30_06415	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
APY30_06420	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
APY30_06425	ENOG4107QJQ	Mate efflux family protein
APY30_06445	ENOG4105VEJ	Heat shock protein
APY30_06450	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
APY30_06460	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
APY30_06475	ENOG4105MP0	transposase
APY30_06495	ENOG4105CNA	YD repeat protein
APY30_06520	ENOG4105CNT	hydrolase family 2
APY30_06525	ENOG4106FKC	arabinogalactan endo-1,4-beta-galactosidase
APY30_06540	ENOG4105C26	Dehydrogenase
APY30_06545	ENOG4105C1G	acyl-Coa dehydrogenase
APY30_06555	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
APY30_06560	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
APY30_06570	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
APY30_06575	ENOG4105EMN	RNA polymerase sigma factor
APY30_06585	ENOG4105C0H	protease
APY30_06590	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
APY30_06595	ENOG4105C3F	Signal peptidase i
APY30_06605	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
APY30_06610	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
APY30_06615	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
APY30_06625	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
APY30_06635	ENOG4107ZXU	DSBA oxidoreductase
APY30_06640	ENOG4108QDE	fad dependent oxidoreductase
APY30_06645	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
APY30_06650	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
APY30_06655	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
APY30_06665	ENOG4105VEQ	Cold shock protein
APY30_06670	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
APY30_06680	ENOG4107QRT	dEAD DEAH box helicase
APY30_06685	ENOG4107T0X	DNA ligase
APY30_06695	ENOG4107T0X	DNA ligase
APY30_06710	ENOG4105BZU	Histidine kinase
APY30_06725	ENOG4105CHU	acetyl-coa acetyltransferase
APY30_06745	ENOG4108VKG	metal-dependent hydrolase
APY30_06760	ENOG4105KSC	Transcriptional regulator, TraR DksA family
APY30_06780	ENOG4105DFF	Rod shape-determining protein mreb
APY30_06785	ENOG4108YZY	peptidylprolyl cis-trans isomerase
APY30_06795	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
APY30_06805	ENOG4105F27	Major Facilitator
APY30_06850	ENOG4105M4H	endoribonuclease L-psp
APY30_06855	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
APY30_06870	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
APY30_06895	ENOG4105K6V	RNA polymerase
APY30_06915	ENOG4108R3D	Electron transport complex
APY30_06925	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
APY30_06940	ENOG4105DA5	(ABC) transporter
APY30_06945	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
APY30_06950	ENOG4108IQI	permease
APY30_06955	ENOG4107QK5	Homocysteine s-methyltransferase
APY30_07005	ENOG4108YXA	Membrane
APY30_07020	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
APY30_07030	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
APY30_07035	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
APY30_07040	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
APY30_07045	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
APY30_07050	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
APY30_07065	ENOG4105DZP	Membrane-associated zinc metalloprotease
APY30_07070	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
APY30_07075	ENOG4105KNE	Phosphatidate cytidylyltransferase
APY30_07080	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
APY30_07085	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
APY30_07090	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
APY30_07095	ENOG4105BZU	Histidine kinase
APY30_07100	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
APY30_07105	ENOG4105CE9	30S ribosomal protein S2
APY30_07140	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
APY30_07145	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
APY30_07155	ENOG4105KUZ	arsenate reductase
APY30_07160	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
APY30_07165	ENOG4105CAQ	asparagine synthetase
APY30_07175	ENOG4108ESX	Receptor
APY30_07185	ENOG4108UWD	Iron-storage protein
APY30_07190	ENOG4105FQ6	thiopurine methyltransferase
APY30_07195	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
APY30_07215	ENOG4105CW7	secretion protein, HlyD family
APY30_07220	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
APY30_07240	ENOG4105DUX	Transporter
APY30_07270	ENOG4105DGW	oligopeptidase A
APY30_07275	ENOG4108V06	Glutathione peroxidase
APY30_07280	ENOG4105DP0	ferredoxin-NADP reductase
APY30_07290	ENOG4107GFK	fumarate
APY30_07320	ENOG4105VEQ	Cold shock protein
APY30_07335	ENOG4105CUZ	uba thif-type nad fad binding protein
APY30_07340	ENOG4105F8V	Hydrolase, tatD family
APY30_07355	ENOG4105C1G	acyl-Coa dehydrogenase
APY30_07365	ENOG4108K3A	Glutathione S-transferase
APY30_07375	ENOG4105CAQ	asparagine synthetase
APY30_07385	ENOG4105CDU	Replicative dna helicase
APY30_07390	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
APY30_07395	ENOG4105CDV	Ompa motb domain protein
APY30_07400	ENOG4105CR8	Transcriptional regulator
APY30_07435	ENOG4105BZU	Histidine kinase
APY30_07445	ENOG4106TD9	Diguanylate cyclase
APY30_07500	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
APY30_07505	ENOG4108Z1B	Cyclase dehydrase
APY30_07515	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
APY30_07520	ENOG41090R7	Ferric uptake
APY30_07525	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
APY30_07530	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
APY30_07535	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
APY30_07540	ENOG4105CFG	Acts as a chaperone (By similarity)
APY30_07545	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
APY30_07550	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
APY30_07580	ENOG4105C5Q	Transcriptional regulator
APY30_07585	ENOG4105BZ1	(ABC) transporter
APY30_07595	ENOG4108URH	decarboxylase
APY30_07605	ENOG4105C7S	Dehydrogenase
APY30_07610	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
APY30_07620	ENOG4105EZE	Cupin 4 family protein
APY30_07630	ENOG4107QTF	adenylosuccinate lyase
APY30_07640	ENOG4105C37	(CBS) domain
APY30_07670	ENOG4105CZV	ABC transporter
APY30_07675	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
APY30_07685	ENOG4108V1T	peptidylprolyl cis-trans isomerase
APY30_07690	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
APY30_07695	ENOG41069P5	Protein slyX homolog
APY30_07710	ENOG4105ETE	Transcriptional regulator (LacI family
APY30_07720	ENOG4105D7K	pfkb domain protein
APY30_07730	ENOG4105C3R	Methionine synthase
APY30_07735	ENOG4105C3R	Methionine synthase
APY30_07745	ENOG4105C1G	acyl-Coa dehydrogenase
APY30_07760	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
APY30_07770	ENOG4105C2N	RNA methyltransferase TrmH family group 3
APY30_07775	ENOG4105BZU	Histidine kinase
APY30_07780	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
APY30_07790	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
APY30_07795	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
APY30_07800	ENOG4105E2Z	phosphate ABC transporter (Permease
APY30_07805	ENOG4105C8U	phosphate abc transporter
APY30_07810	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
APY30_07830	ENOG4107B2H	carbonic anhydrase
APY30_07835	ENOG4105CHH	sulfate transporter
APY30_07840	ENOG4105CSM	endonuclease III
APY30_07850	ENOG4105E39	Enoyl-CoA hydratase
APY30_07855	ENOG4108V1T	peptidylprolyl cis-trans isomerase
APY30_07860	ENOG4105P8F	nudix hydrolase
APY30_07865	ENOG4105KHC	sulfurtransferase
APY30_07895	ENOG4105C5H	ABC transporter
APY30_07900	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
APY30_07905	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
APY30_07930	ENOG4105CJB	Exodeoxyribonuclease I
APY30_07935	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
APY30_07940	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
APY30_07950	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
APY30_07955	ENOG41077A9	carbonic anhydrase
APY30_08000	ENOG4105WH1	Two component transcriptional regulator luxr family
APY30_08040	ENOG4105C5S	asparaginyl-tRNA synthetase
APY30_08045	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
APY30_08050	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
APY30_08055	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
APY30_08060	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
APY30_08070	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
APY30_08085	ENOG4105CIH	Imidazole acetol-phosphate transaminase
APY30_08090	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
APY30_08095	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
APY30_08105	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
APY30_08110	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
APY30_08115	ENOG4105DZG	Dehydrogenase
APY30_08125	ENOG4105CGP	Urocanate hydratase
APY30_08135	ENOG4105C84	Histidine ammonia-lyase
APY30_08140	ENOG4105CI2	imidazolone-5-propionate hydrolase
APY30_08180	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
APY30_08185	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
APY30_08190	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
APY30_08200	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
APY30_08215	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
APY30_08220	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
APY30_08225	ENOG4105CC0	LysR family Transcriptional regulator
APY30_08240	ENOG4105C8Q	Methyl-accepting chemotaxis
APY30_08270	ENOG4105BZU	Histidine kinase
APY30_08290	ENOG4105KWW	Biogenesis protein
APY30_08295	ENOG4107QX9	Thiol disulfide interChange protein
APY30_08300	ENOG4105DA4	cytochrome c-type biogenesis protein
APY30_08305	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
APY30_08315	ENOG41060IM	Heme exporter protein
APY30_08330	ENOG4105EMN	RNA polymerase sigma factor
APY30_08370	ENOG4105CVE	Lytic murein transglycosylase
APY30_08440	ENOG4105EGZ	biosynthesis protein
APY30_08470	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
APY30_08495	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
APY30_08500	ENOG4105BZ1	(ABC) transporter
APY30_08505	ENOG41079KZ	Major Facilitator Superfamily
APY30_08510	ENOG4105DEN	Luciferase family
APY30_08535	ENOG4105CJ3	phosphate transporter
APY30_08550	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
APY30_08560	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
APY30_08565	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
APY30_08575	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
APY30_08580	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
APY30_08585	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
APY30_08590	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
APY30_08595	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
APY30_08600	ENOG4108DG9	Smr protein MutS2
APY30_08605	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
APY30_08610	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
APY30_08615	ENOG4108UM1	dedA family
APY30_08620	ENOG4108K5P	(LipO)protein
APY30_08630	ENOG4105HBR	Rna-binding protein
APY30_08635	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
APY30_08640	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
APY30_08645	ENOG4105EEI	dihydropteroate synthase
APY30_08650	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
APY30_08655	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
APY30_08660	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
APY30_08665	ENOG4107TH8	cina domain protein
APY30_08670	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
APY30_08675	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
APY30_08680	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
APY30_08685	ENOG4105Y3E	Modulates RecA activity (By similarity)
APY30_08690	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
APY30_08695	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
APY30_08705	ENOG4107SDU	Methyl-accepting chemotaxis
APY30_08720	ENOG4105CWB	LysR family transcriptional Regulator
APY30_08760	ENOG4108IAB	Phoh family
APY30_08765	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
APY30_08780	ENOG4107TUS	Dihydrodipicolinate synthase
APY30_08790	ENOG4108Z4U	Ferredoxin
APY30_08795	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
APY30_08805	ENOG4105CXK	mandelate racemase muconate lactonizing
APY30_08810	ENOG4108RTU	Aldolase
APY30_08865	ENOG4105CMG	Carbohydrate kinase
APY30_08870	ENOG4105C93	Xylose Isomerase
APY30_08890	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
APY30_08895	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
APY30_08905	ENOG4105DJ0	Poly(A) Polymerase
APY30_08910	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
APY30_08915	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
APY30_08920	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
APY30_08925	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
APY30_08930	ENOG4107QP8	phosphohexose isomerase
APY30_08965	ENOG4105KU2	hydrolase family 5
APY30_08970	ENOG4108UYB	regulatoR
APY30_08980	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
APY30_08985	ENOG410841Q	phosphoesterase PA-phosphatase related protein
APY30_09000	ENOG4108SXK	Transporter Drug Metabolite Exporter family
APY30_09005	ENOG4105D4A	Cell wall formation (By similarity)
APY30_09010	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
APY30_09025	ENOG4105C26	Dehydrogenase
APY30_09040	ENOG4105CND	Glycosyl transferase, family 2
APY30_09045	ENOG4107BJW	polysaccharide deacetylase
APY30_09090	ENOG4105D98	threonine synthase
APY30_09100	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
APY30_09105	ENOG4105CUT	histidyl-tRNA synthetase
APY30_09115	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
APY30_09120	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
APY30_09125	ENOG4105CIH	Imidazole acetol-phosphate transaminase
APY30_09130	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
APY30_09135	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
APY30_09140	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
APY30_09145	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
APY30_09150	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
APY30_09165	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
APY30_09170	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
APY30_09175	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
APY30_09180	ENOG4105CUB	amino acid
APY30_09185	ENOG4105CUB	amino acid
APY30_09195	ENOG4108JQ1	Dehydrogenase
APY30_09200	ENOG4105CQB	FAD linked oxidase domain protein
APY30_09220	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
APY30_09230	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
APY30_09250	ENOG4105CE1	Ferrous iron transport protein b
APY30_09265	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
APY30_09270	ENOG4108RPX	mosc domain containing protein
APY30_09275	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
APY30_09280	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
APY30_09290	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
APY30_09295	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
APY30_09305	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
APY30_09345	ENOG4105CMM	transposase
APY30_09350	ENOG4105DY9	regulatoR
APY30_09355	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
APY30_09360	ENOG4105CRK	lysyL-tRNA synthetase
APY30_09365	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
APY30_09370	ENOG4105BZU	Histidine kinase
APY30_09375	ENOG4105E39	Enoyl-CoA hydratase
APY30_09380	ENOG4105CEY	Amp-dependent synthetase and ligase
APY30_09390	ENOG4107QM5	aconitate hydratase
APY30_09405	ENOG4107QIJ	Aconitate hydratase 2
APY30_09410	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
APY30_09415	ENOG4105BZU	Histidine kinase
APY30_09420	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
APY30_09425	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
APY30_09430	ENOG4105BZU	Histidine kinase
APY30_09435	ENOG4105C8Q	Methyl-accepting chemotaxis
APY30_09445	ENOG4108V3W	Chemotaxis protein, CheW
APY30_09455	ENOG4105C8Q	Methyl-accepting chemotaxis
APY30_09460	ENOG4105C8Q	Methyl-accepting chemotaxis
APY30_09465	ENOG4105C8Q	Methyl-accepting chemotaxis
APY30_09470	ENOG4105C8Q	Methyl-accepting chemotaxis
APY30_09495	ENOG4105C8Q	Methyl-accepting chemotaxis
APY30_09505	ENOG4105C8Q	Methyl-accepting chemotaxis
APY30_09515	ENOG4105C8Q	Methyl-accepting chemotaxis
APY30_09520	ENOG4105C8Q	Methyl-accepting chemotaxis
APY30_09520	ENOG4105C8Q	Methyl-accepting chemotaxis
APY30_09530	ENOG4105C8Q	Methyl-accepting chemotaxis
APY30_09535	ENOG4105CBS	Chea signal transduction histidine kinase
APY30_09540	ENOG4108VYJ	response regulator receiver protein
APY30_09550	ENOG4108V3W	Chemotaxis protein, CheW
APY30_09555	ENOG4107QJE	Chromosome Partitioning Protein
APY30_09560	ENOG4105ER2	Ompa motb domain protein
APY30_09565	ENOG4105E14	MotA TolQ exbB proton channel
APY30_09580	ENOG4105CMM	transposase
APY30_09625	ENOG4105CMM	transposase
APY30_09650	ENOG4105CBS	Chea signal transduction histidine kinase
APY30_09660	ENOG4108VYJ	response regulator receiver protein
APY30_09670	ENOG4107R21	site-determining protein
APY30_09675	ENOG4105FZW	flagellar biosynthesis regulator FlhF
APY30_09680	ENOG4105D7B	Flagellar biosynthesis protein flha
APY30_09685	ENOG4105D00	flagellar biosynthetic protein flhB
APY30_09690	ENOG4105BZU	Histidine kinase
APY30_09695	ENOG4105BZU	Histidine kinase
APY30_09705	ENOG4105BZU	Histidine kinase
APY30_09710	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
APY30_09715	ENOG4105VS8	Flagellar biosynthetic protein fliq
APY30_09720	ENOG4105CN7	Flagellar biosynthetic protein FliP
APY30_09725	ENOG4105K0P	flagellar biosynthesis protein
APY30_09730	ENOG4105DD5	Flagellar motor switch protein
APY30_09735	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
APY30_09755	ENOG4108JIR	Flagellum-specific ATP synthase
APY30_09765	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
APY30_09770	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
APY30_09775	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
APY30_09780	ENOG4107RGC	Glycosyl transferase, family 2
APY30_09785	ENOG4105CMM	transposase
APY30_09830	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
APY30_09835	ENOG4108P1X	synthase
APY30_09850	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
APY30_09855	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
APY30_09860	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
APY30_09880	ENOG4105MQ3	flagellar protein FliS
APY30_09885	ENOG4107W9T	flagellar hook-associated
APY30_09895	ENOG4105DTJ	flagellar hook-associated protein
APY30_09905	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
APY30_09910	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
APY30_09915	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
APY30_09920	ENOG4105CGA	flagellar basal-body rod protein FlgG
APY30_09925	ENOG4108KPB	Flagellar basal-body rod protein FlgF
APY30_09930	ENOG4105BZE	flagellar hook protein, FlgE
APY30_09935	ENOG410822I	Flagellar hook capping protein
APY30_09940	ENOG4108ZC9	flagellar basal-body rod protein flgc
APY30_09945	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
APY30_09950	ENOG4107R88	Chemotaxis protein (CheV)
APY30_09970	ENOG4105BZU	Histidine kinase
APY30_09975	ENOG4105BZU	Histidine kinase
APY30_09985	ENOG4105BZU	Histidine kinase
APY30_10005	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
APY30_10015	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
APY30_10020	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
APY30_10025	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
APY30_10030	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
APY30_10040	ENOG4105C3M	thioredoxin reductase
APY30_10045	ENOG4105CNU	cell division protein FtsK
APY30_10055	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
APY30_10065	ENOG4105D1H	recombination factor protein RarA
APY30_10070	ENOG41082MI	Protein CrcB homolog
APY30_10075	ENOG4105CHU	acetyl-coa acetyltransferase
APY30_10090	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
APY30_10095	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
APY30_10105	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
APY30_10115	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
APY30_10120	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
APY30_10125	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
APY30_10130	ENOG4105D06	uba thif-type nad fad binding protein
APY30_10280	ENOG4105YES	addiction module antidote protein
APY30_10295	ENOG4105MP0	transposase
APY30_10305	ENOG4105XMH	SpoVT AbrB domain protein
APY30_10400	ENOG4105CMM	transposase
APY30_10425	ENOG4105MP0	transposase
APY30_10445	ENOG4105CGK	Exodeoxyribonuclease III
APY30_10455	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
APY30_10460	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
APY30_10470	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
APY30_10490	ENOG4108N8X	transition metal ion binding
APY30_10515	ENOG4108ZXC	Two component transcriptional regulator, luxr family
APY30_10535	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
APY30_10560	ENOG4105DY9	regulatoR
APY30_10590	ENOG4105W39	Membrane
APY30_10625	ENOG4105RJZ	Transcriptional regulator
APY30_10635	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
APY30_10640	ENOG41090A4	Pterin carbinolamine dehydratase
APY30_10650	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
APY30_10655	ENOG4108NST	exported protein
APY30_10660	ENOG4105EI2	Pseudouridine synthase
APY30_10665	ENOG4105C03	ribonuclease
APY30_10675	ENOG4105C72	UPF0176 protein
APY30_10685	ENOG4108V1T	peptidylprolyl cis-trans isomerase
APY30_10695	ENOG4107QQG	Dehydrogenase
APY30_10770	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
APY30_10775	ENOG4105NI8	Cytosine-specific methyltransferase
APY30_10795	ENOG4107QJE	Chromosome Partitioning Protein
APY30_10830	ENOG4107YH6	single-stranded DNA-binding protein
APY30_10835	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
APY30_10840	ENOG4105NI8	Cytosine-specific methyltransferase
APY30_10875	ENOG41080R2	UPF0102 protein
APY30_10905	ENOG4105F9F	transposase
APY30_11030	ENOG4106NZI	LysR family Transcriptional regulator
APY30_11140	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
APY30_11145	ENOG4107QKA	exodeoxyribonuclease V beta
APY30_11155	ENOG4106NZI	LysR family Transcriptional regulator
APY30_11180	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
APY30_11185	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
APY30_11195	ENOG4105KJF	protein tyrosine phosphatase
APY30_11200	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
APY30_11205	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
APY30_11210	ENOG4105BZ1	(ABC) transporter
APY30_11225	ENOG4108EC8	DNA internalization-related competence protein ComEC
APY30_11235	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
APY30_11240	ENOG4105D60	lipoprotein releasing system transmembrane protein
APY30_11250	ENOG410681N	tpr repeat protein
APY30_11275	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
APY30_11280	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
APY30_11295	ENOG4105CHC	glucokinase (EC 2.7.1.2)
APY30_11300	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
APY30_11305	ENOG4105C01	Dihydroxy-acid dehydratase
APY30_11310	ENOG4108UHU	Aldolase
APY30_11315	ENOG4105BZS	acriflavin resistance protein
APY30_11325	ENOG4105CMM	transposase
APY30_11350	ENOG4105N7H	Cytochrome
APY30_11390	ENOG4105BZU	Histidine kinase
APY30_11395	ENOG4105BZM	domain protein
APY30_11420	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
APY30_11430	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
APY30_11450	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
APY30_11470	ENOG4107SFI	Major Facilitator superfamily
APY30_11490	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
APY30_11495	ENOG4105KST	dependent repressor
APY30_11500	ENOG4108Z6B	deaminase
APY30_11505	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
APY30_11515	ENOG4105CHJ	isochorismatase hydrolase
APY30_11530	ENOG4105WH1	Two component transcriptional regulator luxr family
APY30_11550	ENOG4105DND	Transcriptional regulator
APY30_11560	ENOG4105EVH	UPF0753 protein
APY30_11650	ENOG4107S5I	aldo keto reductase
APY30_11660	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
APY30_11700	ENOG4105DFP	Integrase
APY30_11705	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
APY30_11710	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
APY30_11715	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
APY30_11725	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
APY30_11730	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
APY30_11740	ENOG4105ESV	Glycosyl transferase, family 4
APY30_11745	ENOG4105CFV	Tetratricopeptide repeat protein
APY30_11755	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
APY30_11760	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
APY30_11765	ENOG4105CAT	Cytidine monophosphate kinase
APY30_11770	ENOG4105YK5	50S ribosomal protein L36
APY30_11780	ENOG4105DWY	Agmatine deiminase
APY30_11810	ENOG4105DRS	transport system, permease
APY30_11815	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
APY30_11845	ENOG4105K9H	YciI-like protein
APY30_11850	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
APY30_11855	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
APY30_11860	ENOG4105FE9	pseudouridine synthase
APY30_11880	ENOG4105CHM	Aminotransferase
APY30_11885	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
APY30_11890	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
APY30_11895	ENOG41060IM	Heme exporter protein
APY30_11905	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
APY30_11910	ENOG4105DA4	cytochrome c-type biogenesis protein
APY30_11920	ENOG4105KWW	Biogenesis protein
APY30_11925	ENOG4108M1T	Cytochrome c-type biogenesis protein
APY30_11940	ENOG4108JJ8	(ABC) transporter
APY30_11945	ENOG4108JJ9	ABC, transporter
APY30_11950	ENOG4105C4M	(Ubiquinol oxidase) subunit I
APY30_11955	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
APY30_11975	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
APY30_11980	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
APY30_11990	ENOG4105CH7	arginosuccinase
APY30_11995	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
APY30_12005	ENOG4105CAS	nag kinase
APY30_12020	ENOG4105CDH	Citrulline--aspartate ligase
APY30_12025	ENOG4105DBV	ornithine carbamoyltransferase
APY30_12035	ENOG4105C8N	cysteinyl-tRNA synthetase
APY30_12040	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
APY30_12050	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
APY30_12060	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
APY30_12065	ENOG4105CD3	dihydroorotase
APY30_12085	ENOG4105CPD	ethanolamine ammonia-lyase
APY30_12090	ENOG4107FQ9	ethanolamine ammonia-lyase
APY30_12130	ENOG4105CMM	transposase
APY30_12145	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
APY30_12150	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
APY30_12155	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
APY30_12165	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
APY30_12170	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
APY30_12175	ENOG4105BZU	Histidine kinase
APY30_12190	ENOG4105ECY	inositol monophosphatase
APY30_12195	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
APY30_12210	ENOG4105C5H	ABC transporter
APY30_12215	ENOG4105C1J	atp-dependent rna helicase
APY30_12220	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
APY30_12225	ENOG4105CNG	UPF0061 protein
APY30_12235	ENOG4108RXX	maleylacetoacetate isomerase
APY30_12240	ENOG4105VEQ	Cold shock protein
APY30_12245	ENOG4108VWS	Yaeq family
APY30_12250	ENOG4105CBX	hi0933 family
APY30_12260	ENOG4105D0M	Protease HtpX homolog
APY30_12265	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
APY30_12270	ENOG4105CHR	reductase
APY30_12290	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
APY30_12295	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
APY30_12300	ENOG4105K8N	protein family UPF0079, ATPase
APY30_12305	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
APY30_12310	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
APY30_12315	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
APY30_12325	ENOG4105E6M	Sulphatase-modifying factor protein
APY30_12335	ENOG4105DQE	DNA ligase
APY30_12410	ENOG4105C26	Dehydrogenase
APY30_12450	ENOG4108V3W	Chemotaxis protein, CheW
APY30_12455	ENOG4105C8Q	Methyl-accepting chemotaxis
APY30_12460	ENOG4108VX5	3-methyladenine DNA glycosylase
APY30_12465	ENOG4107QRT	dEAD DEAH box helicase
APY30_12480	ENOG4105KB2	stringent starvation protein b
APY30_12485	ENOG4107MKT	Stringent starvation protein a
APY30_12490	ENOG4105EIX	cytochrome c1
APY30_12495	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
APY30_12500	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
APY30_12505	ENOG4105E4C	Lytic transglycosylase catalytic
APY30_12520	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
APY30_12525	ENOG4105C9A	Phoh family
APY30_12535	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
APY30_12545	ENOG4108JU5	Magnesium and cobalt efflux protein
APY30_12570	ENOG4105D38	putrescine abc transporter
APY30_12575	ENOG4105F38	ABC transporter, permease
APY30_12600	ENOG4107RUE	extracellular solute-binding protein family 1
APY30_12605	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
APY30_12620	ENOG4105CFQ	glutamine synthetase
APY30_12625	ENOG4105CJP	fad dependent oxidoreductase
APY30_12630	ENOG4105BZU	Histidine kinase
APY30_12635	ENOG4105W3S	hemerythrin-like, metal-binding protein
APY30_12640	ENOG4105CSH	Transporter
APY30_12650	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
APY30_12655	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
APY30_12660	ENOG4105FCD	Major Facilitator
APY30_12680	ENOG4106BRA	Membrane
APY30_12685	ENOG4105BZU	Histidine kinase
APY30_12690	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
APY30_12695	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
APY30_12700	ENOG4105C7I	Dehydrogenase
APY30_12710	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
APY30_12715	ENOG4105BZS	acriflavin resistance protein
APY30_12720	ENOG4108M60	Transcriptional regulator
APY30_12725	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
APY30_12730	ENOG4105DE4	1-phosphofructokinase
APY30_12735	ENOG4105DM4	PTS System
APY30_12790	ENOG4107QT7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
APY30_12795	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
APY30_12800	ENOG4105VIE	preprotein translocase, subunit YajC
APY30_12805	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
APY30_12810	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
APY30_12860	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
APY30_12865	ENOG4105E08	Glycoside hydrolase, family 9
APY30_12875	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
APY30_12880	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
APY30_12895	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
APY30_12900	ENOG4106H78	methyltransferase
APY30_12905	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
APY30_12940	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
APY30_12995	ENOG4107QTZ	amino acid
APY30_13010	ENOG4105DC7	peptidase M24
APY30_13020	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
APY30_13035	ENOG41080HI	glycine oxidase
APY30_13040	ENOG4105CTU	Proline racemase
APY30_13050	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
APY30_13055	ENOG4105CEN	a g-specific adenine glycosylase
APY30_13060	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
APY30_13065	ENOG4105CQZ	Histidine kinase
APY30_13080	ENOG4105DKD	Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity)
APY30_13095	ENOG4105QNF	Outer membrane lipoprotein
APY30_13105	ENOG4105CSU	acyl-Coa dehydrogenase
APY30_13115	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
APY30_13135	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
APY30_13140	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
APY30_13145	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
APY30_13170	ENOG4108NQK	Catalyzes the transfer of a glucuronic acid (GlcA) residue from UDP-glucuronate to mannose-alpha-1,3-glucose-beta- 1,4-glucose-P-P-polyisoprenyl to form the lipid-linked tetrasaccharide GlcA-Man-Glc(2)-PP-Pol, with a glucuronic acid- beta-mannose linkage. Is involved in the biosynthesis of the exopolysaccharide xanthan, since it catalyzes the fourth glycosylation step in the assembly of the pentasaccharide-P-P- polyisoprenyl repeating unit of xanthan. Is unable to use the trisaccharide acceptor freed from the pyrophosphate lipid moiety. Does not show specificity for the lipidic portion of the acceptor. Shows diminished activity when tested with 6-O-acetyl-mannose- alpha-1,3-glucose-beta-1,4-glucose-P-P-polyisoprenyl, a
APY30_13180	ENOG4107Y2G	Glycosyl transferase (Group 1
APY30_13205	ENOG4105D3Q	Sugar transferase
APY30_13225	ENOG4105WJX	transcriptional regulator MERR family
APY30_13230	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
APY30_13235	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
APY30_13240	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
APY30_13245	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
APY30_13250	ENOG41082NX	50s ribosomal protein l35
APY30_13255	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
APY30_13260	ENOG4105C22	threonyL-tRNA synthetase
APY30_13265	ENOG4105ETE	Transcriptional regulator (LacI family
APY30_13345	ENOG4105CMA	conjugation trbi family protein
APY30_13380	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
APY30_13420	ENOG4105EWT	decarboxylase family
APY30_13425	ENOG4108KPZ	tonB-dependent Receptor
APY30_13430	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
APY30_13440	ENOG4105M2J	Glutaredoxin
APY30_13445	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
APY30_13450	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
APY30_13455	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
APY30_13465	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
APY30_13475	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
APY30_13480	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
APY30_13485	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
APY30_13490	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
APY30_13495	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
APY30_13500	ENOG4105CHV	Transcription elongation factor NusA
APY30_13505	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
APY30_13515	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
APY30_13520	ENOG4105C8S	subunit m
APY30_13525	ENOG4105D65	subunit l
APY30_13535	ENOG4105DF2	NADH dehydrogenase subunit j
APY30_13540	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
APY30_13545	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
APY30_13550	ENOG4107R0R	NADH dehydrogenase subunit g
APY30_13555	ENOG4107QIZ	NADH dehydrogenase
APY30_13560	ENOG4105GKE	subunit e
APY30_13565	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
APY30_13570	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
APY30_13575	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
APY30_13580	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
APY30_13595	ENOG4105CP7	Triose-phosphate isomerase
APY30_13600	ENOG4107FW0	short-chain dehydrogenase reductase
APY30_13615	ENOG4105BZU	Histidine kinase
APY30_13635	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
APY30_13640	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
APY30_13645	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
APY30_13655	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
APY30_13665	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
APY30_13670	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
APY30_13690	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
APY30_13695	ENOG4105C5I	Dehydrogenase
APY30_13700	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
APY30_13705	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
APY30_13715	ENOG4105DJ4	phosphatidylserine decarboxylase
APY30_13735	ENOG4105MP0	transposase
APY30_13745	ENOG4105D7A	ATP-binding protein
APY30_13750	ENOG4107VIJ	nudix hydrolase
APY30_13765	ENOG4108RRZ	Transcription elongation factor GreB
APY30_13770	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
APY30_13780	ENOG4106A2Z	transcriptional regulator antitoxin, MazE
APY30_13840	ENOG4105DHP	deoxycytidine triphosphate deaminase
APY30_13865	ENOG4105C9K	Endothelin-converting enzyme 1
APY30_13870	ENOG4105C9K	Endothelin-converting enzyme 1
APY30_13890	ENOG4105DC8	reductase
APY30_13895	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
APY30_13905	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
APY30_13910	ENOG4105K4H	Nlp p60 protein
APY30_13915	ENOG4105K4H	Nlp p60 protein
APY30_13925	ENOG41082K6	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
APY30_13930	ENOG4105CK2	sodium dicarboxylate symporter
APY30_13935	ENOG4105G6Z	alkaline phosphatase
APY30_13945	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
APY30_13950	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
APY30_13955	ENOG4105CTB	Polyprenyl synthetase
APY30_13970	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
APY30_13975	ENOG4105N42	UPF0307 protein
APY30_13980	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
APY30_13990	ENOG4105QD6	exported protein
APY30_13995	ENOG4105C03	ribonuclease
APY30_14000	ENOG4108Z03	MAF-like protein
APY30_14005	ENOG4105MPN	Membrane
APY30_14020	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
APY30_14035	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
APY30_14050	ENOG4105C8T	Leucyl-tRNA synthetase
APY30_14060	ENOG4107QR8	Thioredoxin
APY30_14095	ENOG4105WG9	Conserved Protein
APY30_14100	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
APY30_14140	ENOG4105BZ1	(ABC) transporter
APY30_14165	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
APY30_14170	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
APY30_14185	ENOG4105FQP	Beta-lactamase
APY30_14190	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
APY30_14210	ENOG4105BZU	Histidine kinase
APY30_14215	ENOG4105FE9	pseudouridine synthase
APY30_14220	ENOG4105BZU	Histidine kinase
APY30_14285	ENOG4105CMQ	Chloride channel
APY30_14305	ENOG4105UGU	tonB-dependent Receptor
APY30_14340	ENOG4105F27	Major Facilitator
APY30_14345	ENOG4105EJC	lysr family transcriptional regulator
APY30_14355	ENOG4105CF7	AraC family transcriptional regulator
APY30_14365	ENOG4105EQ2	LysR family Transcriptional regulator
APY30_14370	ENOG4107SET	aldo keto reductase
APY30_14375	ENOG4108JGH	Tetr family transcriptional regulator
APY30_14380	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
APY30_14385	ENOG4105BZS	acriflavin resistance protein
APY30_14390	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
APY30_14400	ENOG4105MYN	Zinc uptake regulation protein
APY30_14405	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
APY30_14430	ENOG4105CT7	inner membrane cred family protein
APY30_14445	ENOG4105EB3	Histidine kinase
APY30_14450	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
APY30_14455	ENOG4105D6S	protein involved in catabolism of external DNA
APY30_14465	ENOG4108JA2	transcriptioN-repair coupling factor
APY30_14495	ENOG4105CBS	Chea signal transduction histidine kinase
APY30_14500	ENOG4105C8Q	Methyl-accepting chemotaxis
APY30_14505	ENOG4108V3W	Chemotaxis protein, CheW
APY30_14510	ENOG4105BZU	Histidine kinase
APY30_14515	ENOG4105BZU	Histidine kinase
APY30_14520	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
APY30_14525	ENOG4107RZC	phospholipase d
APY30_14530	ENOG4105C9K	Endothelin-converting enzyme 1
APY30_14540	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
APY30_14545	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
APY30_14555	ENOG4105EUB	pirin domain protein
APY30_14570	ENOG4105EUB	pirin domain protein
APY30_14575	ENOG4105D22	carbon starvation protein
APY30_14580	ENOG4105VCD	cytoplasmic protein
APY30_14625	ENOG4107XAN	XdhC and CoxI family
APY30_14635	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
APY30_14640	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
APY30_14655	ENOG4108UUM	single-stranded DNA-binding protein
APY30_14660	ENOG4105EAH	synthase
APY30_14670	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
APY30_14685	ENOG4105CFH	Aspartokinase
APY30_14690	ENOG4105JAB	phenazine biosynthesis protein, phzf family
APY30_14695	ENOG4105JAB	phenazine biosynthesis protein, phzf family
APY30_14705	ENOG4108Z9K	Osmotically inducible protein
APY30_14710	ENOG4105CXT	aspartate transcarbamylase
APY30_14715	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
APY30_14720	ENOG4108UJU	UPF0301 protein
APY30_14730	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
APY30_14745	ENOG4105CZX	twitching motility protein
APY30_14750	ENOG4105CZX	twitching motility protein
APY30_14755	ENOG4105DFA	alanine racemase domain protein
APY30_14760	ENOG4105II7	pyrroline-5-carboxylate reductase
APY30_14770	ENOG4105FAA	peptidase M23
APY30_14790	ENOG4108Z0Z	intracellular protease Pfpi family
APY30_14810	ENOG4105C3K	feS assembly ATPase SufC
APY30_14815	ENOG4105JRK	feS assembly protein SufD
APY30_14820	ENOG4105C9B	Cysteine desulfurase
APY30_14835	ENOG4108IU3	tonb-dependent siderophore receptor
APY30_14840	ENOG4107E2E	PKHD-type hydroxylase
APY30_14865	ENOG4105CJ2	(LipO)protein
APY30_14870	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
APY30_14885	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
APY30_14900	ENOG4105EHM	Aminoglycoside phosphotransferase
APY30_14905	ENOG4108S0S	Nucleotidyl transferase
APY30_14915	ENOG4105C02	permease
APY30_14925	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
APY30_14940	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
APY30_14960	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
APY30_14970	ENOG4105C2X	Arabinose 5-phosphate isomerase
APY30_14975	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
APY30_14985	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
APY30_14990	ENOG4108IUZ	ABC transporter
APY30_14995	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
APY30_15000	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
APY30_15005	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
APY30_15010	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
APY30_15015	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
APY30_15025	ENOG41080Z8	PHOSPHOCARRIER protein
APY30_15030	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
APY30_15035	ENOG4105CJW	magnesium transporter
APY30_15040	ENOG4107UWA	esterase
APY30_15045	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
APY30_15050	ENOG4105C4M	(Ubiquinol oxidase) subunit I
APY30_15060	ENOG4105C85	amino acid
APY30_15075	ENOG4105CMM	transposase
APY30_15100	ENOG4105CUB	amino acid
APY30_15130	ENOG4105QV4	Tryptophan halogenase
APY30_15160	ENOG4108Z4X	TRANSCRIPTIONal
APY30_15170	ENOG4105MP0	transposase
APY30_15190	ENOG4106032	Glutathionylspermidine synthase
APY30_15215	ENOG4108P9J	Phage shock protein A
APY30_15225	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
APY30_15230	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
APY30_15235	ENOG4105D49	3-dehydroquinate synthase
APY30_15245	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
APY30_15255	ENOG4105BZU	Histidine kinase
APY30_15260	ENOG4105BZU	Histidine kinase
APY30_15265	ENOG4105BZU	Histidine kinase
APY30_15270	ENOG4105BZU	Histidine kinase
APY30_15275	ENOG4108YYC	ycei family
APY30_15295	ENOG4105EJQ	L-serine dehydratase
APY30_15305	ENOG4105CFH	Aspartokinase
APY30_15310	ENOG4105C28	cystathionine
APY30_15315	ENOG4106TYC	homoserine o-acetyltransferase (EC 2.3.1.31)
APY30_15320	ENOG4105DR5	peptidase
APY30_15325	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
APY30_15330	ENOG4108UT2	hemolysin iii
APY30_15335	ENOG41066T0	asmA family
APY30_15340	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
APY30_15350	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
APY30_15355	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
APY30_15365	ENOG4105D05	Receptor
APY30_15385	ENOG4105CMM	transposase
APY30_15405	ENOG4108IG5	Transcriptional regulator
APY30_15415	ENOG4107QPN	acyl-Coa dehydrogenase
APY30_15445	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
APY30_15450	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
APY30_15460	ENOG4105KK4	UPF0060 membrane protein
APY30_15465	ENOG4105DXN	mazG family
APY30_15470	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
APY30_15475	ENOG4107RK2	ADP-ribose diphosphatase NudE
APY30_15485	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
APY30_15490	ENOG4105CHC	glucokinase (EC 2.7.1.2)
APY30_15505	ENOG4105VRS	hydrolase family 18
APY30_15510	ENOG4105E2D	ec 3.2.1.52
APY30_15525	ENOG4108JJA	ABC, transporter
APY30_15555	ENOG4105CWX	Alpha-1,2-mannosidase
APY30_15590	ENOG4106N3A	copper homeostasis protein cutc
APY30_15605	ENOG4105D9U	N-acetyltransferase
APY30_15620	ENOG4105CBS	Chea signal transduction histidine kinase
APY30_15625	ENOG4105C8Q	Methyl-accepting chemotaxis
APY30_15630	ENOG410807Z	Modulation of CheA activity in response to attractants (Chemotaxis
APY30_15635	ENOG4105M3Z	response regulator
APY30_15640	ENOG4108UNF	response regulator
APY30_15645	ENOG4105D7Z	glutathione synthase
APY30_15655	ENOG41065RQ	ADP-ribosylation crystallin J1
APY30_15660	ENOG41072GX	Peptidase M22 Glycoprotease
APY30_15665	ENOG4105DVT	helicase
APY30_15675	ENOG4105BZ4	penicillin-binding protein
APY30_15690	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
APY30_15695	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
APY30_15700	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
APY30_15705	ENOG4105Z85	coenzyme PQQ synthesis
APY30_15710	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
APY30_15725	ENOG4105CHC	glucokinase (EC 2.7.1.2)
APY30_15735	ENOG4105CQ7	ATP-dependent helicase
APY30_15745	ENOG4105C9U	ATP-dependent DNA helicase RecQ
APY30_15780	ENOG4105C8Q	Methyl-accepting chemotaxis
APY30_15800	ENOG410903D	sensor protein
APY30_15805	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
APY30_15815	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
APY30_15825	ENOG4105KCK	Peptidoglycan-associated lipoprotein
APY30_15830	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
APY30_15845	ENOG4105E02	MotA TolQ exbB proton channel
APY30_15850	ENOG4107YD3	Thioesterase
APY30_15855	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
APY30_15865	ENOG4105DFH	Transport of potassium into the cell (By similarity)
APY30_15870	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
APY30_15875	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
APY30_15880	ENOG4105CDY	transcriptional regulatory protein
APY30_15895	ENOG4105C9M	aspartyl-trna synthetase
APY30_15910	ENOG4108ISG	Major Facilitator
APY30_15930	ENOG4105ETT	transcriptional Regulator, LysR family
APY30_15940	ENOG4105C5H	ABC transporter
APY30_15965	ENOG4107RNH	Outer membrane receptor FepA
APY30_15975	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
APY30_16000	ENOG4105GAV	receptor
APY30_16015	ENOG4105C6X	Major Facilitator
APY30_16025	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
APY30_16045	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
APY30_16050	ENOG4108YZT	Adenosylcobinamide kinase
APY30_16055	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
APY30_16065	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
APY30_16070	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
APY30_16085	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
APY30_16090	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
APY30_16095	ENOG4105E2Y	ABC, transporter
APY30_16100	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
APY30_16105	ENOG4105GVF	(ABC) transporter
APY30_16110	ENOG4105CPC	Aldo Keto reductase
APY30_16120	ENOG4107ZSV	Receptor
APY30_16125	ENOG41082IR	Excinuclease ABC C subunit domain protein
APY30_16160	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
APY30_16165	ENOG4108K4C	ec 3.1.3.12
APY30_16170	ENOG4105BZP	glycoside hydrolase 15-related
APY30_16175	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
APY30_16180	ENOG4105DZG	Dehydrogenase
APY30_16185	ENOG4105C8Q	Methyl-accepting chemotaxis
APY30_16190	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
APY30_16205	ENOG4105C34	Pseudouridine synthase
APY30_16210	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
APY30_16220	ENOG4105C4K	Nad synthetase
APY30_16235	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
APY30_16240	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
APY30_16245	ENOG4107TUY	Histidine kinase
APY30_16255	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
APY30_16260	ENOG4107QHF	type ii secretion system protein e
APY30_16265	ENOG4107QHF	type ii secretion system protein e
APY30_16280	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
APY30_16285	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
APY30_16305	ENOG4105CMM	transposase
APY30_16320	ENOG4105BZU	Histidine kinase
APY30_16325	ENOG4105ETX	regulatoR
APY30_16335	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
APY30_16425	ENOG4105W5Q	DNA repair protein (RadC
APY30_16430	ENOG4105ESI	atpase involved in dna repair
APY30_16455	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
APY30_16490	ENOG4106E1W	protein with protein kinase and helix-hairpin-helix DNA-binding
APY30_16495	ENOG4105UM3	Inherit from NOG: serine threonine phosphoprotein phosphatase
APY30_16500	ENOG4108M24	von Willebrand factor, type A
APY30_16520	ENOG4105CNA	YD repeat protein
APY30_16550	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
APY30_16555	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
APY30_16580	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
APY30_16600	ENOG4105MP0	transposase
APY30_16640	ENOG4105EIB	trna rrna methyltransferase
APY30_16650	ENOG4105CD8	aminopeptidase N
APY30_16680	ENOG4105BZS	acriflavin resistance protein
APY30_16690	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
APY30_16695	ENOG4105C11	sulfate adenylyltransferase), subunit 2
APY30_16700	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
APY30_16705	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
APY30_16710	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
APY30_16730	ENOG4105BZU	Histidine kinase
APY30_16745	ENOG4107R11	Transcriptional regulator
APY30_16750	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
APY30_16765	ENOG4108UVJ	appr-1-p processing domain protein
APY30_16770	ENOG4107R1Y	fructose-bisphosphate aldolase
APY30_16775	ENOG4105CA9	Pyruvate kinase
APY30_16785	ENOG4105BZA	Phosphoglycerate kinase
APY30_16805	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
APY30_16815	ENOG4105EIF	outer membrane protein W
APY30_16820	ENOG4105EIF	outer membrane protein W
APY30_16830	ENOG4107S76	domain protein
APY30_16835	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
APY30_16840	ENOG4105E0C	molybdate abc transporter
APY30_16845	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
APY30_16900	ENOG4105CNM	Receptor
APY30_16920	ENOG4105CV1	Transketolase (EC 2.2.1.1)
APY30_16925	ENOG4105CK2	sodium dicarboxylate symporter
APY30_16935	ENOG4107QVM	von Willebrand factor, type A
APY30_16955	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
APY30_16960	ENOG4105E4G	Type IV pilus
APY30_16985	ENOG4108JQC	penicillin-binding protein 1A
APY30_17000	ENOG4105NRA	50s ribosomal protein l31 type b
APY30_17005	ENOG4105DU0	nucleoside hydrolase
APY30_17010	ENOG4105CB5	ATP-dependent DNA helicase recG
APY30_17015	ENOG4105KME	endoribonuclease L-psp
APY30_17020	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
APY30_17025	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
APY30_17030	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
APY30_17035	ENOG4105DSJ	YicC domain protein
APY30_17040	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
APY30_17050	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
APY30_17055	ENOG4105CSA	Coproporphyrinogen iii oxidase
APY30_17070	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
APY30_17080	ENOG4107RAQ	aminopeptidase
APY30_17095	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
APY30_17100	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
APY30_17110	ENOG4105E66	phosphoriboisomerase A
APY30_17120	ENOG41063JG	Transcriptional regulator
APY30_17125	ENOG4105VCQ	rubredoxin
APY30_17130	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
APY30_17140	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
APY30_17145	ENOG41061ZR	Transcriptional regulator
APY30_17155	ENOG4105CIH	Imidazole acetol-phosphate transaminase
APY30_17185	ENOG4105C8Y	Acetylornithine aminotransferase
APY30_17190	ENOG4105EYW	Ion transport protein
APY30_17205	ENOG410841Q	phosphoesterase PA-phosphatase related protein
APY30_17210	ENOG4105FFC	UPF0187 protein
APY30_17220	ENOG4105DFU	Cell wall formation (By similarity)
APY30_17225	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
APY30_17245	ENOG4105MP0	transposase
APY30_17250	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
APY30_17260	ENOG4105F0N	pyrophosphate phospho-hydrolase
APY30_17275	ENOG4105ECQ	AraC Family Transcriptional Regulator
APY30_17280	ENOG4108M3R	transcriptional activator CadC
APY30_17285	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
APY30_17295	ENOG4105C8Q	Methyl-accepting chemotaxis
APY30_17300	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
APY30_17305	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
APY30_17320	ENOG4105C7B	Threonine dehydratase
APY30_17325	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
APY30_17330	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
APY30_17335	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
APY30_17340	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
APY30_17345	ENOG4108MP6	LysR family Transcriptional regulator
APY30_17360	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
APY30_17365	ENOG4105DFG	type I secretion outer membrane protein
APY30_17370	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
APY30_17375	ENOG4105D1S	lipid A biosynthesis
APY30_17400	ENOG4105C6K	Malic enzyme
APY30_17405	ENOG4105CK2	sodium dicarboxylate symporter
APY30_17420	ENOG4105CQZ	Histidine kinase
APY30_17425	ENOG4105CSH	Transporter
APY30_17435	ENOG4105F04	LysR family Transcriptional regulator
APY30_17445	ENOG4105CPC	Aldo Keto reductase
APY30_17460	ENOG4105WH1	Two component transcriptional regulator luxr family
APY30_17465	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
APY30_17470	ENOG4105DHQ	Histidine kinase
APY30_17485	ENOG4105D4T	Citrate transporter
APY30_17490	ENOG4105CHR	reductase
APY30_17495	ENOG4105ETE	Transcriptional regulator (LacI family
APY30_17510	ENOG4107QW3	Sucrose phosphorylase
APY30_17525	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
APY30_17545	ENOG4105CEY	Amp-dependent synthetase and ligase
APY30_17550	ENOG4105DDW	LysR family Transcriptional regulator
APY30_17585	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
APY30_17590	ENOG4105D0A	hydroxylase
APY30_17600	ENOG4108WBT	adenosyltransferase
APY30_17615	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
APY30_17620	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
APY30_17625	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
APY30_17630	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
APY30_17635	ENOG4105NWN	ApaG protein
APY30_17640	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
APY30_17660	ENOG4105DEF	Extracellular solute-binding protein, family 5
APY30_17685	ENOG4108UZX	fmn reductase
APY30_17690	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
APY30_17700	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
APY30_17705	ENOG4105D7T	ABC transporter
APY30_17710	ENOG4107T8P	acyl-Coa dehydrogenase
APY30_17715	ENOG4107SM7	Transcriptional regulator
APY30_17730	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
APY30_17735	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
APY30_17755	ENOG41080IJ	Diacylglycerol kinase
APY30_17770	ENOG4105ETX	regulatoR
APY30_17775	ENOG4108UJV	acyl-CoA thioesterase i
APY30_17780	ENOG4108I0Y	(ABC) transporter
APY30_17790	ENOG4105E2B	Taurine dioxygenase
APY30_17805	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
APY30_17825	ENOG4105D05	Receptor
APY30_17835	ENOG4105CPC	Aldo Keto reductase
APY30_17840	ENOG4105D9N	nucleoside
APY30_17845	ENOG4108RVA	ribokinase
APY30_17855	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
APY30_17860	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
APY30_17870	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
APY30_17875	ENOG4105D6F	Phosphatase
APY30_17905	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
APY30_17915	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
APY30_17985	ENOG4105SYT	Methylenetetrahydrofolate reductase
APY30_17995	ENOG4105M6F	mutator MutT protein
APY30_18000	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
APY30_18005	ENOG4105DR5	peptidase
APY30_18015	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
APY30_18020	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
APY30_18025	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
APY30_18030	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
APY30_18035	ENOG4105CPF	Cell wall formation (By similarity)
APY30_18040	ENOG4105DFU	Cell wall formation (By similarity)
APY30_18045	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
APY30_18055	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
APY30_18060	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
APY30_18065	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
APY30_18070	ENOG4105CJN	penicillin-binding protein
APY30_18075	ENOG4106932	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
APY30_18080	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
APY30_18085	ENOG4108V6E	Cell division protein mraZ
APY30_18110	ENOG41082RQ	UPF0102 protein
APY30_18115	ENOG4105S2T	inner membrane protein YbcI
APY30_18120	ENOG4105CQB	FAD linked oxidase domain protein
APY30_18135	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
APY30_18140	ENOG4105C08	Histidine kinase
APY30_18145	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
APY30_18150	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
APY30_18155	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
APY30_18175	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
APY30_18180	ENOG4107YIM	Involved in the transcription termination process (By similarity)
APY30_18185	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
APY30_18190	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
APY30_18215	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
APY30_18225	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
APY30_18230	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
APY30_18240	ENOG4105C5H	ABC transporter
APY30_18255	ENOG4105JAB	phenazine biosynthesis protein, phzf family
APY30_18260	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
APY30_18275	ENOG4108QBQ	Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione (By similarity)
APY30_18300	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
APY30_18305	ENOG4105JJR	Histidine kinase
APY30_18325	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
APY30_18330	ENOG4106RE7	Cytochrome
APY30_18340	ENOG4108Z33	Thiol disulfide Interchange Protein
APY30_18350	ENOG4105C94	Transporter
APY30_18355	ENOG4105C26	Dehydrogenase
APY30_18360	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
APY30_18365	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
APY30_18375	ENOG4105CE4	GlcNAc 6-P deacetylase
APY30_18380	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
APY30_18385	ENOG4105ETE	Transcriptional regulator (LacI family
APY30_18395	ENOG4105FDP	GntR family transcriptional regulator
APY30_18410	ENOG4105CNT	hydrolase family 2
APY30_18435	ENOG4108RTD	type II secretion system protein K
APY30_18445	ENOG4105X5Z	General secretion pathway protein I
APY30_18450	ENOG4105VWV	general secretion pathway protein h
APY30_18455	ENOG4108VAU	general secretion pathway protein G
APY30_18460	ENOG4105D7Q	type ii secretion system
APY30_18465	ENOG4107QHF	type ii secretion system protein e
APY30_18470	ENOG4105GVR	general secretion pathway protein D
APY30_18510	ENOG4105CHR	reductase
APY30_18520	ENOG4105BZU	Histidine kinase
APY30_18530	ENOG4105BZU	Histidine kinase
APY30_18535	ENOG4105W4M	Transport-associated protein
APY30_18540	ENOG4105D9R	oxidoreductase
APY30_18545	ENOG4108J5G	6-phosphogluconate dehydrogenase
APY30_18590	ENOG4105EGI	Transcriptional regulator
APY30_18600	ENOG4105CN1	protease
APY30_18605	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
APY30_18610	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
APY30_18625	ENOG4105DZ1	carboxypeptidase
APY30_18635	ENOG4105K6T	rare lipoprotein A
APY30_18640	ENOG4105CVE	Lytic murein transglycosylase
APY30_18650	ENOG4105CNI	cell division protein FtsW
APY30_18665	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
APY30_18670	ENOG4105DFF	Rod shape-determining protein mreb
APY30_18680	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
APY30_18705	ENOG4108Q1J	Extracellular solute-binding protein, family 3
APY30_18710	ENOG4105DZG	Dehydrogenase
APY30_18730	ENOG4105CD8	aminopeptidase N
APY30_18735	ENOG4105BZU	Histidine kinase
APY30_18740	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
APY30_18765	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
APY30_18770	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
APY30_18775	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
APY30_18790	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
APY30_18800	ENOG4105WD1	Membrane
APY30_18845	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
APY30_18850	ENOG4108NEV	two component transcriptional regulator, LytTR family
APY30_18855	ENOG4108HRK	Histidine kinase
APY30_18865	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
APY30_18880	ENOG4105BZU	Histidine kinase
APY30_18885	ENOG4105CHH	sulfate transporter
APY30_18890	ENOG4106R7G	Glycoside hydrolase family 5
APY30_18895	ENOG4105C8Q	Methyl-accepting chemotaxis
APY30_18935	ENOG4105E53	ec 3.2.1.28
APY30_18945	ENOG4105D7N	magnesium and cobalt transport protein CorA
APY30_18965	ENOG4105F87	Dehydratase
APY30_18970	ENOG4105DFI	Membrane
APY30_18990	ENOG4105BZU	Histidine kinase
APY30_18995	ENOG4107QS8	(LipO)protein
APY30_19005	ENOG4105C5Z	peptidase
APY30_19010	ENOG4105EYF	MMPL domain protein
APY30_19030	ENOG4105MP0	transposase
APY30_19045	ENOG4105CHF	Glutathione S-transferase
APY30_19055	ENOG4105PDP	Short chain dehydrogenase
APY30_19070	ENOG4107GJV	short-chain dehydrogenase reductase
APY30_19110	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
APY30_19145	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
APY30_19150	ENOG4105DRR	Transcriptional regulator, GntR family
APY30_19160	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
APY30_19165	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
APY30_19170	ENOG41065ZS	Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme- A to the apo- acyl-carrier-protein of the malonate decarboxylase to yield holo- acyl-carrier-protein (By similarity)
APY30_19185	ENOG4105WSE	Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity)
APY30_19215	ENOG4108YYC	ycei family
APY30_19220	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
APY30_19240	ENOG4105EX9	Membrane
APY30_19245	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
APY30_19270	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
APY30_19285	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
APY30_19290	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
APY30_19295	ENOG4108K8S	endonuclease I
APY30_19300	ENOG4105E1F	short-chain dehydrogenase reductase
APY30_19310	ENOG4105VV6	START domain-containing protein
APY30_19325	ENOG4105VF7	tolerance protein
APY30_19330	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
APY30_19335	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
APY30_19340	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
APY30_19350	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
APY30_19365	ENOG4105MP0	transposase
APY30_19375	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
APY30_19400	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
APY30_19405	ENOG4108HPI	phosphatidate Cytidylyltransferase
APY30_19430	ENOG41077RS	Phosphatase
APY30_19435	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
APY30_19440	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
APY30_19445	ENOG4105DC1	bifunctional purine biosynthesis protein purh
APY30_19455	ENOG4105C12	Phosphoribosylglycinamide synthetase
APY30_19465	ENOG4105EM2	membrane
APY30_19480	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
APY30_19495	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
APY30_19515	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
APY30_19540	ENOG4105BZU	Histidine kinase
APY30_19545	ENOG4108UQY	Iron-storage protein
APY30_19555	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
APY30_19570	ENOG4108UJD	30S ribosomal protein S9
APY30_19575	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
APY30_19580	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
APY30_19590	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
APY30_19595	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
APY30_19605	ENOG4105DK0	Indole-3-glycerol phosphate synthase
APY30_19610	ENOG4108I0Q	anthranilate phosphoribosyltransferase
APY30_19620	ENOG4105DDQ	anthranilate synthase
APY30_19630	ENOG4105CRQ	synthase (Component I)
APY30_19635	ENOG4107TE5	Lipid kinase
APY30_19640	ENOG4105KD7	acetyltransferase
APY30_19655	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
APY30_19660	ENOG4105C8V	SAICAR synthetase
APY30_19690	ENOG4105MP0	transposase
APY30_19715	ENOG4105D65	subunit l
APY30_19720	ENOG4108ZE9	Monovalent cation H antiporter subunit C
APY30_19725	ENOG4107R4Z	monovalent cation h antiporter subunit d
APY30_19735	ENOG4105W4C	monovalent cation H antiporter subunit F
APY30_19740	ENOG4105KJM	monovalent cation h antiporter subunit g
APY30_19755	ENOG4105F1J	Homogentisate 1,2-dioxygenase
APY30_19760	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
APY30_19775	ENOG4105DUX	Transporter
APY30_19780	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
APY30_19790	ENOG4107RUY	(E1 component), alpha subunit
APY30_19795	ENOG4105CPP	Dehydrogenase, E1 component
APY30_19805	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
APY30_19810	ENOG4105C1J	atp-dependent rna helicase
APY30_19820	ENOG4105CHR	reductase
APY30_19825	ENOG4105BZS	acriflavin resistance protein
APY30_19860	ENOG4107ZQV	short-chain dehydrogenase reductase
APY30_19865	ENOG4105K4T	epimerase
APY30_19890	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
APY30_19895	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
APY30_19900	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
APY30_19905	ENOG4105BZU	Histidine kinase
APY30_19910	ENOG4105CKW	Inner membrane protein yedI
APY30_19920	ENOG4107RES	phosphoglycerol transferase I
APY30_19925	ENOG4105EGS	Mechanosensitive ion channel
APY30_19945	ENOG4105FTC	Lytic transglycosylase catalytic
APY30_19955	ENOG4105K44	type iii secretion
APY30_19960	ENOG4108TN6	type iii secretion
APY30_19970	ENOG4108JIR	Flagellum-specific ATP synthase
APY30_19985	ENOG4107Y59	type iii secretion
APY30_20005	ENOG4108HR8	type iii secretion
APY30_20025	ENOG4105VS8	Flagellar biosynthetic protein fliq
APY30_20070	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
APY30_20075	ENOG41081UC	Inherit from COG: Competence protein
APY30_20080	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
APY30_20085	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
APY30_20095	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
APY30_20100	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
APY30_20135	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
APY30_20140	ENOG4105MH3	Protein of unknown function (DUF2490)
APY30_20155	ENOG4107HP6	Transcriptional regulator
APY30_20165	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
APY30_20170	ENOG4105F2Z	3-oxoadipate enol-lactonase
APY30_20175	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
APY30_20180	ENOG4105EU7	Protocatechuate 3,4-dioxygenase, beta
APY30_20190	ENOG4105CHU	acetyl-coa acetyltransferase
APY30_20215	ENOG4105E98	transcriptional regulator DeoR family
APY30_20220	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
APY30_20225	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
APY30_20230	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
APY30_20240	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
APY30_20270	ENOG4105CPI	Metal Dependent Phosphohydrolase
APY30_20275	ENOG4105D2S	major facilitator superfamily
APY30_20285	ENOG4108Z0R	Transferase
APY30_20305	ENOG4105C01	Dihydroxy-acid dehydratase
APY30_20365	ENOG4105ECR	NmrA family
APY30_20385	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
APY30_20400	ENOG4108UZX	fmn reductase
APY30_20405	ENOG4105DZ2	Transcriptional regulator
APY30_20410	ENOG4105WPN	DNA integration recombination invertion protein
APY30_20425	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
APY30_20435	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
APY30_20440	ENOG4105EB3	Histidine kinase
APY30_20445	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
APY30_20465	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
APY30_20470	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
APY30_20485	ENOG4105D94	Major Facilitator Superfamily
APY30_20500	ENOG4105CMM	transposase
APY30_20515	ENOG4105F8V	Hydrolase, tatD family
APY30_20520	ENOG4105ETT	transcriptional Regulator, LysR family
APY30_20535	ENOG4105C7N	Xanthine uracil vitamin C permease
APY30_20545	ENOG4105DU0	nucleoside hydrolase
APY30_20555	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
APY30_20565	ENOG4107RTG	Major Facilitator superfamily
APY30_20570	ENOG4105EQ2	LysR family Transcriptional regulator
APY30_20580	ENOG4105C5R	Aminotransferase
APY30_20600	ENOG4105E1J	oxidoreductase
APY30_20605	ENOG4105VT2	5-hydroxyisourate hydrolase
APY30_20610	ENOG4108W15	Protein of unknown function (DUF1456)
APY30_20615	ENOG4105CQ7	ATP-dependent helicase
APY30_20625	ENOG4108KPZ	tonB-dependent Receptor
APY30_20630	ENOG4108R99	pseudouridine synthase
APY30_20645	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
APY30_20675	ENOG4108ZHJ	Organic hydroperoxide resistance protein
APY30_20680	ENOG4105K56	Transcriptional regulator
APY30_20685	ENOG4105D6Z	AFG1 family ATPase
APY30_20695	ENOG4108TZV	Membrane
APY30_20805	ENOG4105D85	methylase
APY30_20910	ENOG4105C1G	acyl-Coa dehydrogenase
APY30_20915	ENOG4107QX3	carboxylase
APY30_20945	ENOG4105BZU	Histidine kinase
APY30_20955	ENOG4107QP3	malate synthase g
APY30_20960	ENOG4105DUM	transcriptional regulator, lysR family
APY30_20995	ENOG4105DGW	oligopeptidase A
APY30_21000	ENOG4105D44	asparaginase
APY30_21010	ENOG4108YZN	class I peptide chain release factor
APY30_21020	ENOG4105DR9	pseudouridine synthase
APY30_21030	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
APY30_21040	ENOG4105CPF	Cell wall formation (By similarity)
APY30_21055	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
APY30_21060	ENOG410680H	amp-dependent synthetase and ligase
APY30_21065	ENOG4105PI0	Ferredoxin
APY30_21070	ENOG4108J2P	Alpha beta hydrolase fold
APY30_21080	ENOG4105E2T	synthase III
APY30_21095	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
APY30_21115	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
APY30_21120	ENOG4108TQ9	Histidine kinase
APY30_21125	ENOG4105C7K	acetolactate synthase
APY30_21135	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
APY30_21140	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
APY30_21145	ENOG4107YZP	Rhodanese domain protein
APY30_21180	ENOG4105CHU	acetyl-coa acetyltransferase
APY30_21195	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
APY30_21200	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
APY30_21205	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
APY30_21210	ENOG4105CUX	Signal transduction histidine kinase
APY30_21215	ENOG4105BZU	Histidine kinase
APY30_21225	ENOG4105C5F	glutamine synthetase
APY30_21230	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
APY30_21240	ENOG4108V1U	phospholipid-binding protein
APY30_21265	ENOG4105KA0	thioesterase Superfamily protein
APY30_21270	ENOG4107RZC	phospholipase d
APY30_21280	ENOG4105M4E	phosphohistidine phosphatase, SixA
APY30_21285	ENOG4105D1F	ATP-binding protein
APY30_21340	ENOG4105E90	ABC transporter
APY30_21345	ENOG4108IJ8	ABC transporter
APY30_21360	ENOG4105DKW	ABC transporter
APY30_21370	ENOG4105D78	K07001 NTE family protein
APY30_21375	ENOG4105CNM	Receptor
APY30_21380	ENOG4108YXU	transcriptional regulator AsnC family
APY30_21385	ENOG4105MIR	Phenylalanine 4-monooxygenase
APY30_21400	ENOG4107TDE	lipolytic protein G-D-S-L family
APY30_21410	ENOG4105CHR	reductase
APY30_21415	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
APY30_21420	ENOG4105ETE	Transcriptional regulator (LacI family
APY30_21425	ENOG4105DSG	hydrolase family 43
APY30_21430	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
APY30_21440	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
APY30_21455	ENOG4105EBR	Carboxylesterase
APY30_21480	ENOG4105MA0	exported protein
APY30_21485	ENOG4105CFU	surface antigen
APY30_21490	ENOG4105D05	Receptor
APY30_21495	ENOG4107RDJ	Sulfotransferase
APY30_21505	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
APY30_21510	ENOG4107QHF	type ii secretion system protein e
APY30_21520	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
APY30_21530	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
APY30_21535	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
APY30_21550	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
APY30_21570	ENOG4105DH7	May be involved in recombination (By similarity)
APY30_21575	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
APY30_21580	ENOG4105C93	Xylose Isomerase
APY30_21585	ENOG4105ETE	Transcriptional regulator (LacI family
APY30_21590	ENOG4105D0H	Alpha-glucuronidase (EC 3.2.1.139)
APY30_21600	ENOG4105CXK	mandelate racemase muconate lactonizing
APY30_21615	ENOG4105DEI	Mannitol dehydrogenase
APY30_21655	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
APY30_21685	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
APY30_21690	ENOG4105CNT	hydrolase family 2
APY30_21695	ENOG4105D2H	Uronic isomerase
APY30_21725	ENOG4105CT4	transporter
APY30_21730	ENOG4105DT9	hydrolase family 43
APY30_21760	ENOG4105CMM	transposase
APY30_21790	ENOG4105E55	glycerol-3-phosphate acyltransferase
APY30_21800	ENOG4105ETE	Transcriptional regulator (LacI family
APY30_21820	ENOG4105QV4	Tryptophan halogenase
APY30_21825	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
APY30_21830	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
APY30_21835	ENOG4108YXG	UPF0502 protein
APY30_21845	ENOG4105KNA	-acetyltransferase
APY30_21850	ENOG4105C4R	Atp-dependent dna helicase
APY30_21855	ENOG4107104	thymidine kinase
APY30_21860	ENOG4105BZU	Histidine kinase
APY30_21865	ENOG4105DJ9	glucan biosynthesis protein
APY30_21875	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
APY30_21925	ENOG4105DSB	aldose 1-epimerase
APY30_21935	ENOG4105K5B	UPF0225 protein
APY30_21940	ENOG4105EJ9	Membrane
APY30_21960	ENOG4105EUJ	GTP cyclohydrolase i
APY30_21970	ENOG4105ZQC	membrane protein AaeX
APY30_21975	ENOG4105Y49	secretion protein, HlyD family
APY30_21985	ENOG4105DR8	Membrane
APY30_21990	ENOG4105CSH	Transporter
APY30_21995	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
APY30_22055	ENOG4105D3G	Pseudouridine synthase
APY30_22060	ENOG4105MP0	transposase
APY30_22070	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
APY30_22105	ENOG4107QKA	exodeoxyribonuclease V beta
APY30_22110	ENOG4105DSY	exodeoxyribonuclease V, gamma
APY30_22125	ENOG4105DHJ	ABC, transporter
APY30_22130	ENOG4105CY3	ABC transporter, permease
APY30_22135	ENOG4107PE3	Mammalian cell entry related domain protein
APY30_22150	ENOG410903C	(LipO)protein
APY30_22160	ENOG4108V06	Glutathione peroxidase
APY30_22170	ENOG4107QSV	RmuC domain protein
APY30_22175	ENOG4105CIS	alcohol dehydrogenase
APY30_22180	ENOG4105SKE	transcriptional Regulator LysR family
APY30_22190	ENOG4108TGY	Glutathione S-transferase
APY30_22200	ENOG4105CUB	amino acid
APY30_22205	ENOG4105CWX	Alpha-1,2-mannosidase
APY30_22215	ENOG4105BZU	Histidine kinase
APY30_22235	ENOG4105DR4	Methyltransferase
APY30_22240	ENOG4105DU1	integral membrane protein, terc
APY30_22250	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
APY30_22265	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
APY30_22270	ENOG4108ZJ4	polysaccharide deacetylase
APY30_22280	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
APY30_22285	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
APY30_22300	ENOG4108C33	Resolvase
APY30_22315	ENOG4105MP0	transposase
APY30_22370	ENOG4105XMH	SpoVT AbrB domain protein
APY30_22405	ENOG4105CVE	Lytic murein transglycosylase
APY30_22425	ENOG4108C33	Resolvase
APY30_22585	ENOG4105C0H	protease