locus-tag	class	description
XcfCFBP6988P_00110	COG0697	spore germination
XcfCFBP6988P_00130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XcfCFBP6988P_00135	COG0180	Tryptophanyl-tRNA synthetase
XcfCFBP6988P_00140	COG3237	CsbD-like
XcfCFBP6988P_00180	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
XcfCFBP6988P_00195	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
XcfCFBP6988P_00245	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XcfCFBP6988P_00275	COG1199	ATP-dependent helicase activity
XcfCFBP6988P_00290	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
XcfCFBP6988P_00365	COG0625	glutathione transferase activity
XcfCFBP6988P_00400	COG4555	ABC transporter
XcfCFBP6988P_00410	COG1476	TRANSCRIPTIONal
XcfCFBP6988P_00430	COG1230	cation diffusion facilitator family transporter
XcfCFBP6988P_00440	COG4774	siderophore transport
XcfCFBP6988P_00455	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XcfCFBP6988P_00460	COG1131	(ABC) transporter
XcfCFBP6988P_00465	COG0842	Transport permease protein
XcfCFBP6988P_00470	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XcfCFBP6988P_00490	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XcfCFBP6988P_00500	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XcfCFBP6988P_00510	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XcfCFBP6988P_00525	COG0045	succinate-CoA ligase (ADP-forming) activity
XcfCFBP6988P_00525	COG1042	CoA-binding domain protein
XcfCFBP6988P_00525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XcfCFBP6988P_00530	COG2239	Acts as a magnesium transporter
XcfCFBP6988P_00550	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XcfCFBP6988P_00555	COG3387	PFAM Glycoside hydrolase 15-related
XcfCFBP6988P_00570	COG3100	YcgL domain-containing protein
XcfCFBP6988P_00575	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XcfCFBP6988P_00585	COG0463	Glycosyl transferase, family 2
XcfCFBP6988P_00605	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6988P_00645	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XcfCFBP6988P_00660	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XcfCFBP6988P_00690	COG1506	peptidase
XcfCFBP6988P_00690	COG0823	Involved in the tonB-independent uptake of proteins
XcfCFBP6988P_00690	COG4946	Tricorn protease homolog
XcfCFBP6988P_00710	COG0408	coproporphyrinogen oxidase activity
XcfCFBP6988P_00745	COG0515	serine threonine protein kinase
XcfCFBP6988P_00750	COG0631	protein serine/threonine phosphatase activity
XcfCFBP6988P_00925	COG0210	DNA helicase
XcfCFBP6988P_00935	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XcfCFBP6988P_00940	COG0583	DNA-binding transcription factor activity
XcfCFBP6988P_00945	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XcfCFBP6988P_00960	COG2159	amidohydrolase
XcfCFBP6988P_00990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcfCFBP6988P_01010	COG0357	Ribosomal RNA small subunit methyltransferase G
XcfCFBP6988P_01015	COG3540	Alkaline phosphatase
XcfCFBP6988P_01025	COG2091	lysine biosynthetic process via aminoadipic acid
XcfCFBP6988P_01040	COG0708	Exodeoxyribonuclease III
XcfCFBP6988P_01045	COG1940	carbohydrate kinase activity
XcfCFBP6988P_01045	COG1846	Transcriptional regulator
XcfCFBP6988P_01055	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XcfCFBP6988P_01070	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XcfCFBP6988P_01075	COG3162	membrane
XcfCFBP6988P_01085	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XcfCFBP6988P_01115	COG3507	Belongs to the glycosyl hydrolase 43 family
XcfCFBP6988P_01135	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6988P_01140	COG0179	Fumarylacetoacetate (FAA) hydrolase
XcfCFBP6988P_01145	COG4948	Mandelate Racemase Muconate Lactonizing
XcfCFBP6988P_01150	COG3254	rhamnose metabolic process
XcfCFBP6988P_01155	COG0738	Major facilitator superfamily
XcfCFBP6988P_01160	COG1414	Transcriptional regulator
XcfCFBP6988P_01165	COG1971	Probably functions as a manganese efflux pump
XcfCFBP6988P_01170	COG2205	protein histidine kinase activity
XcfCFBP6988P_01185	COG3459	Glycosyltransferase 36 associated
XcfCFBP6988P_01190	COG2211	Major facilitator Superfamily
XcfCFBP6988P_01195	COG3265	gluconokinase activity
XcfCFBP6988P_01205	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XcfCFBP6988P_01225	COG2911	Protein conserved in bacteria
XcfCFBP6988P_01230	COG0729	surface antigen
XcfCFBP6988P_01260	COG0752	glycyl-tRNA synthetase alpha subunit
XcfCFBP6988P_01265	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XcfCFBP6988P_01285	COG0519	Catalyzes the synthesis of GMP from XMP
XcfCFBP6988P_01285	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XcfCFBP6988P_01295	COG0805	protein transport
XcfCFBP6988P_01300	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XcfCFBP6988P_01305	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XcfCFBP6988P_01315	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
XcfCFBP6988P_01335	COG2974	May be involved in recombination
XcfCFBP6988P_01340	COG0037	tRNA processing
XcfCFBP6988P_01345	COG2115	Belongs to the xylose isomerase family
XcfCFBP6988P_01355	COG3661	Belongs to the glycosyl hydrolase 67 family
XcfCFBP6988P_01365	COG4948	Mandelate Racemase Muconate Lactonizing
XcfCFBP6988P_01375	COG1472	Belongs to the glycosyl hydrolase 3 family
XcfCFBP6988P_01380	COG0246	Mannitol dehydrogenase
XcfCFBP6988P_01430	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XcfCFBP6988P_01460	COG3386	PFAM SMP-30 Gluconolaconase
XcfCFBP6988P_01470	COG3250	beta-galactosidase activity
XcfCFBP6988P_01475	COG1904	glucuronate isomerase
XcfCFBP6988P_01490	COG3693	PFAM glycoside hydrolase, family 10
XcfCFBP6988P_01505	COG2211	Major facilitator Superfamily
XcfCFBP6988P_01560	COG0604	alcohol dehydrogenase
XcfCFBP6988P_01560	COG3321	synthase
XcfCFBP6988P_01560	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6988P_01565	COG2937	Belongs to the GPAT DAPAT family
XcfCFBP6988P_01600	COG0284	orotidine-5'-phosphate decarboxylase activity
XcfCFBP6988P_01605	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
XcfCFBP6988P_01615	COG3132	Protein of unknown function, DUF480
XcfCFBP6988P_01630	COG0210	DNA helicase
XcfCFBP6988P_01635	COG1435	thymidine kinase activity
XcfCFBP6988P_01645	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
XcfCFBP6988P_01655	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
XcfCFBP6988P_01685	COG3135	benzoate transporter
XcfCFBP6988P_01705	COG0676	glucose-6-phosphate 1-epimerase activity
XcfCFBP6988P_01715	COG3012	SEC-C Motif Domain Protein
XcfCFBP6988P_01720	COG0730	response to heat
XcfCFBP6988P_01740	COG0302	gtp cyclohydrolase
XcfCFBP6988P_01755	COG1566	PFAM secretion protein HlyD family protein
XcfCFBP6988P_01765	COG1289	transmembrane transporter activity
XcfCFBP6988P_01770	COG0477	Major facilitator Superfamily
XcfCFBP6988P_01780	COG0583	DNA-binding transcription factor activity
XcfCFBP6988P_01785	COG4221	oxidoreductase activity
XcfCFBP6988P_01795	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XcfCFBP6988P_01855	COG0564	pseudouridine synthase activity
XcfCFBP6988P_01895	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6988P_01935	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
XcfCFBP6988P_01940	COG1074	ATP-dependent DNA helicase activity
XcfCFBP6988P_01945	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
XcfCFBP6988P_01980	COG1127	ABC transporter
XcfCFBP6988P_01985	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XcfCFBP6988P_01990	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XcfCFBP6988P_02005	COG2853	Lipoprotein
XcfCFBP6988P_02015	COG0386	Belongs to the glutathione peroxidase family
XcfCFBP6988P_02035	COG0625	glutathione transferase activity
XcfCFBP6988P_02045	COG0531	amino acid
XcfCFBP6988P_02050	COG3537	Alpha-1,2-mannosidase
XcfCFBP6988P_02065	COG3706	GGDEF domain
XcfCFBP6988P_02070	COG3835	regulator
XcfCFBP6988P_02095	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XcfCFBP6988P_02100	COG0861	Integral membrane protein TerC family
XcfCFBP6988P_02110	COG0584	glycerophosphoryl diester phosphodiesterase
XcfCFBP6988P_02125	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
XcfCFBP6988P_02140	COG0706	membrane insertase activity
XcfCFBP6988P_02145	COG0594	ribonuclease P activity
XcfCFBP6988P_02160	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
XcfCFBP6988P_02170	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
XcfCFBP6988P_02175	COG0187	DNA topoisomerase II activity
XcfCFBP6988P_02185	COG0501	Belongs to the peptidase M48B family
XcfCFBP6988P_02220	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
XcfCFBP6988P_02230	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XcfCFBP6988P_02280	COG0793	Belongs to the peptidase S41A family
XcfCFBP6988P_02285	COG4942	peptidase
XcfCFBP6988P_02295	COG2234	aminopeptidase activity
XcfCFBP6988P_02305	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XcfCFBP6988P_02310	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XcfCFBP6988P_02315	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XcfCFBP6988P_02325	COG1064	alcohol dehydrogenase
XcfCFBP6988P_02340	COG0493	'glutamate synthase
XcfCFBP6988P_02345	COG0070	glutamate synthase
XcfCFBP6988P_02345	COG0069	glutamate synthase activity
XcfCFBP6988P_02345	COG0067	glutamate synthase
XcfCFBP6988P_02435	COG1205	dead DEAH box helicase
XcfCFBP6988P_02435	COG1111	helicase
XcfCFBP6988P_02440	COG1272	protein, Hemolysin III
XcfCFBP6988P_02460	COG0300	oxidoreductase activity
XcfCFBP6988P_02465	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6988P_02490	COG2249	NAD(P)H dehydrogenase (quinone) activity
XcfCFBP6988P_02520	COG3237	CsbD-like
XcfCFBP6988P_02570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XcfCFBP6988P_02580	COG0477	Major facilitator Superfamily
XcfCFBP6988P_02625	COG0714	Associated with various cellular activities
XcfCFBP6988P_02670	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
XcfCFBP6988P_02680	COG4772	TonB-dependent receptor
XcfCFBP6988P_02695	COG1012	belongs to the aldehyde dehydrogenase family
XcfCFBP6988P_02720	COG1304	FMN binding
XcfCFBP6988P_02735	COG4585	Histidine kinase
XcfCFBP6988P_02740	COG2197	response regulator
XcfCFBP6988P_02760	COG3710	Transcriptional regulator
XcfCFBP6988P_02765	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
XcfCFBP6988P_02905	COG0366	Alpha amylase catalytic
XcfCFBP6988P_02910	COG0366	Alpha amylase catalytic
XcfCFBP6988P_02915	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XcfCFBP6988P_02935	COG0657	acetylesterase activity
XcfCFBP6988P_02935	COG2755	lipolytic protein G-D-S-L family
XcfCFBP6988P_02945	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XcfCFBP6988P_02960	COG3507	Belongs to the glycosyl hydrolase 43 family
XcfCFBP6988P_02965	COG1609	Transcriptional regulator
XcfCFBP6988P_02975	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
XcfCFBP6988P_02980	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6988P_02990	COG2755	lipolytic protein G-D-S-L family
XcfCFBP6988P_03000	COG3186	Phenylalanine-4-hydroxylase
XcfCFBP6988P_03005	COG1522	sequence-specific DNA binding
XcfCFBP6988P_03015	COG1752	Esterase of the alpha-beta hydrolase superfamily
XcfCFBP6988P_03025	COG1119	ATPase activity
XcfCFBP6988P_03040	COG1125	glycine betaine transport
XcfCFBP6988P_03055	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XcfCFBP6988P_03085	COG0489	protein tyrosine kinase activity
XcfCFBP6988P_03090	COG2062	phosphohistidine phosphatase, SixA
XcfCFBP6988P_03100	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XcfCFBP6988P_03145	COG1968	undecaprenyl-diphosphatase activity
XcfCFBP6988P_03155	COG0174	glutamine synthetase
XcfCFBP6988P_03160	COG0347	Belongs to the P(II) protein family
XcfCFBP6988P_03165	COG0004	ammonium transporteR
XcfCFBP6988P_03170	COG3852	Histidine kinase
XcfCFBP6988P_03175	COG2204	response regulator
XcfCFBP6988P_03180	COG2032	superoxide dismutase activity
XcfCFBP6988P_03185	COG2032	superoxide dismutase activity
XcfCFBP6988P_03190	COG0346	lactoylglutathione lyase activity
XcfCFBP6988P_03200	COG0183	Belongs to the thiolase family
XcfCFBP6988P_03235	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XcfCFBP6988P_03240	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
XcfCFBP6988P_03245	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
XcfCFBP6988P_03260	COG0028	Belongs to the TPP enzyme family
XcfCFBP6988P_03265	COG2205	protein histidine kinase activity
XcfCFBP6988P_03290	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
XcfCFBP6988P_03305	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XcfCFBP6988P_03315	COG0596	Alpha beta hydrolase
XcfCFBP6988P_03320	COG0727	PFAM Uncharacterised protein family (UPF0153)
XcfCFBP6988P_03325	COG0318	PFAM AMP-dependent synthetase and ligase
XcfCFBP6988P_03330	COG0745	RESPONSE REGULATOR receiver
XcfCFBP6988P_03340	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XcfCFBP6988P_03370	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XcfCFBP6988P_03380	COG0564	pseudouridine synthase activity
XcfCFBP6988P_03400	COG1446	asparaginase
XcfCFBP6988P_03405	COG0339	signal peptide processing
XcfCFBP6988P_03445	COG0475	glutathione-regulated potassium exporter activity
XcfCFBP6988P_03450	COG0583	DNA-binding transcription factor activity
XcfCFBP6988P_03455	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
XcfCFBP6988P_03460	COG2224	Isocitrate lyase
XcfCFBP6988P_03490	COG4770	biotin carboxylase activity
XcfCFBP6988P_03495	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XcfCFBP6988P_03500	COG1960	acyl-CoA dehydrogenase activity
XcfCFBP6988P_03570	COG0697	spore germination
XcfCFBP6988P_03580	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
XcfCFBP6988P_03585	COG1846	Transcriptional regulator
XcfCFBP6988P_03590	COG1764	response to oxidative stress
XcfCFBP6988P_03620	COG2130	NADP-dependent
XcfCFBP6988P_03635	COG1187	pseudouridine synthase activity
XcfCFBP6988P_03650	COG1643	Atp-dependent helicase
XcfCFBP6988P_03655	COG4807	Protein conserved in bacteria
XcfCFBP6988P_03660	COG2351	hydroxyisourate hydrolase activity
XcfCFBP6988P_03665	COG2072	flavoprotein involved in K transport
XcfCFBP6988P_03685	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
XcfCFBP6988P_03695	COG0583	DNA-binding transcription factor activity
XcfCFBP6988P_03730	COG2252	PERMEase
XcfCFBP6988P_03755	COG0084	hydrolase, TatD family'
XcfCFBP6988P_03765	COG0583	DNA-binding transcription factor activity
XcfCFBP6988P_03770	COG2814	Major facilitator Superfamily
XcfCFBP6988P_03780	COG2267	carboxylic ester hydrolase activity
XcfCFBP6988P_03785	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
XcfCFBP6988P_03790	COG1902	pentaerythritol trinitrate reductase activity
XcfCFBP6988P_03810	COG0745	RESPONSE REGULATOR receiver
XcfCFBP6988P_03815	COG2205	protein histidine kinase activity
XcfCFBP6988P_03820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcfCFBP6988P_03845	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XcfCFBP6988P_03850	COG0583	DNA-binding transcription factor activity
XcfCFBP6988P_03885	COG0702	epimerase
XcfCFBP6988P_03890	COG1733	regulation of RNA biosynthetic process
XcfCFBP6988P_03925	COG0129	dihydroxy-acid dehydratase activity
XcfCFBP6988P_03940	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
XcfCFBP6988P_03995	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
XcfCFBP6988P_04000	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
XcfCFBP6988P_04025	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
XcfCFBP6988P_04030	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
XcfCFBP6988P_04040	COG3485	protocatechuate 3,4-dioxygenase
XcfCFBP6988P_04045	COG3485	protocatechuate 3,4-dioxygenase
XcfCFBP6988P_04055	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XcfCFBP6988P_04060	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XcfCFBP6988P_04070	COG1414	Transcriptional regulator
XcfCFBP6988P_04080	COG0657	acetylesterase activity
XcfCFBP6988P_04090	COG0445	tRNA wobble uridine modification
XcfCFBP6988P_04100	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
XcfCFBP6988P_04125	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6988P_04130	COG2267	carboxylic ester hydrolase activity
XcfCFBP6988P_04140	COG0156	8-amino-7-oxononanoate synthase activity
XcfCFBP6988P_04145	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
XcfCFBP6988P_04150	COG1040	competence protein
XcfCFBP6988P_04155	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
XcfCFBP6988P_04195	COG5297	Belongs to the glycosyl hydrolase family 6
XcfCFBP6988P_04245	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XcfCFBP6988P_04320	COG1511	domain protein
XcfCFBP6988P_04320	COG3264	Mechanosensitive ion channel
XcfCFBP6988P_04325	COG1368	sulfuric ester hydrolase activity
XcfCFBP6988P_04335	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XcfCFBP6988P_04340	COG2354	Protein conserved in bacteria
XcfCFBP6988P_04350	COG0297	glycogen (starch) synthase activity
XcfCFBP6988P_04355	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XcfCFBP6988P_04360	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XcfCFBP6988P_04385	COG0702	epimerase
XcfCFBP6988P_04390	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6988P_04425	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcfCFBP6988P_04430	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6988P_04440	COG0513	Belongs to the DEAD box helicase family
XcfCFBP6988P_04445	COG0508	dehydrogenase complex catalyzes the overall conversion of
XcfCFBP6988P_04460	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
XcfCFBP6988P_04470	COG3483	tryptophan 2,3-dioxygenase activity
XcfCFBP6988P_04475	COG3104	oligopeptide transport
XcfCFBP6988P_04495	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
XcfCFBP6988P_04515	COG1320	monovalent cation:proton antiporter activity
XcfCFBP6988P_04520	COG2212	antiporter activity
XcfCFBP6988P_04530	COG0651	ATP synthesis coupled electron transport
XcfCFBP6988P_04535	COG1006	Multisubunit Na H antiporter MnhC subunit
XcfCFBP6988P_04540	COG2111	Na H antiporter
XcfCFBP6988P_04540	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XcfCFBP6988P_04565	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
XcfCFBP6988P_04570	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
XcfCFBP6988P_04585	COG0456	acetyltransferase
XcfCFBP6988P_04590	COG1597	lipid kinase activity
XcfCFBP6988P_04615	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
XcfCFBP6988P_04620	COG0134	indole-3-glycerol-phosphate synthase activity
XcfCFBP6988P_04630	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XcfCFBP6988P_04635	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
XcfCFBP6988P_04645	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
XcfCFBP6988P_04655	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
XcfCFBP6988P_04670	COG1051	belongs to the nudix hydrolase family
XcfCFBP6988P_04710	COG0316	Belongs to the HesB IscA family
XcfCFBP6988P_04730	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XcfCFBP6988P_04750	COG2814	Major facilitator Superfamily
XcfCFBP6988P_04760	COG2814	Major facilitator Superfamily
XcfCFBP6988P_04765	COG1289	transmembrane transporter activity
XcfCFBP6988P_04770	COG0151	Belongs to the GarS family
XcfCFBP6988P_04780	COG0138	bifunctional purine biosynthesis protein purh
XcfCFBP6988P_04785	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XcfCFBP6988P_04790	COG2267	carboxylic ester hydrolase activity
XcfCFBP6988P_04795	COG2453	phosphatase
XcfCFBP6988P_04795	COG0671	phosphoesterase, PA-phosphatase related
XcfCFBP6988P_04820	COG4589	Belongs to the CDS family
XcfCFBP6988P_04825	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
XcfCFBP6988P_04850	COG2264	protein methyltransferase activity
XcfCFBP6988P_04870	COG0439	Biotin carboxylase
XcfCFBP6988P_04880	COG0511	ligase activity, forming carbon-carbon bonds
XcfCFBP6988P_04885	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
XcfCFBP6988P_04895	COG1324	tolerance protein
XcfCFBP6988P_04905	COG2356	endonuclease I
XcfCFBP6988P_04915	COG0459	protein refolding
XcfCFBP6988P_04930	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XcfCFBP6988P_04945	COG3386	PFAM SMP-30 Gluconolaconase
XcfCFBP6988P_04955	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
XcfCFBP6988P_04960	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XcfCFBP6988P_04985	COG0778	Nitroreductase
XcfCFBP6988P_04990	COG2353	YceI-like domain
XcfCFBP6988P_05020	COG3052	prosthetic group binding
XcfCFBP6988P_05045	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XcfCFBP6988P_05055	COG1802	Transcriptional regulator
XcfCFBP6988P_05230	COG1082	Xylose isomerase domain protein TIM barrel
XcfCFBP6988P_05255	COG4221	oxidoreductase activity
XcfCFBP6988P_05270	COG4221	oxidoreductase activity
XcfCFBP6988P_05280	COG0435	Glutathione S-transferase
XcfCFBP6988P_05315	COG0823	Involved in the tonB-independent uptake of proteins
XcfCFBP6988P_05315	COG1506	peptidase
XcfCFBP6988P_05350	COG0697	spore germination
XcfCFBP6988P_05370	COG1113	amino acid transport
XcfCFBP6988P_05390	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
XcfCFBP6988P_05440	COG0840	transmembrane signaling receptor activity
XcfCFBP6988P_05445	COG5297	Belongs to the glycosyl hydrolase family 6
XcfCFBP6988P_05445	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XcfCFBP6988P_05450	COG0659	secondary active sulfate transmembrane transporter activity
XcfCFBP6988P_05475	COG2943	transferase activity, transferring hexosyl groups
XcfCFBP6988P_05485	COG3275	phosphorelay sensor kinase activity
XcfCFBP6988P_05495	COG0181	hydroxymethylbilane synthase activity
XcfCFBP6988P_05525	COG1505	serine-type exopeptidase activity
XcfCFBP6988P_05530	COG0436	Aminotransferase
XcfCFBP6988P_05540	COG2832	Protein of unknown function (DUF454)
XcfCFBP6988P_05550	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
XcfCFBP6988P_05560	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XcfCFBP6988P_05565	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
XcfCFBP6988P_05570	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
XcfCFBP6988P_05595	COG2226	methyltransferase
XcfCFBP6988P_05600	COG5001	Diguanylate cyclase
XcfCFBP6988P_05600	COG3300	MHYT domain
XcfCFBP6988P_05605	COG0308	aminopeptidase N
XcfCFBP6988P_05655	COG3284	Transcriptional regulator
XcfCFBP6988P_05660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XcfCFBP6988P_05665	COG1077	Cell shape determining protein MreB Mrl
XcfCFBP6988P_05670	COG1792	Involved in formation and maintenance of cell shape
XcfCFBP6988P_05685	COG0772	Belongs to the SEDS family
XcfCFBP6988P_05695	COG2951	lytic endotransglycosylase activity
XcfCFBP6988P_05700	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XcfCFBP6988P_05710	COG1686	Belongs to the peptidase S11 family
XcfCFBP6988P_05720	COG2921	Belongs to the UPF0250 family
XcfCFBP6988P_05725	COG0321	lipoyl(octanoyl) transferase activity
XcfCFBP6988P_05730	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
XcfCFBP6988P_05745	COG0583	DNA-binding transcription factor activity
XcfCFBP6988P_05755	COG1056	cytidyltransferase-related domain
XcfCFBP6988P_05755	COG1051	belongs to the nudix hydrolase family
XcfCFBP6988P_05790	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
XcfCFBP6988P_05795	COG0673	inositol 2-dehydrogenase activity
XcfCFBP6988P_05800	COG2823	Periplasmic or secreted lipoprotein
XcfCFBP6988P_05805	COG4251	negative regulation of phosphorylation
XcfCFBP6988P_05810	COG0784	Response regulator, receiver
XcfCFBP6988P_05815	COG4191	Histidine kinase
XcfCFBP6988P_05820	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XcfCFBP6988P_05880	COG1459	type II secretion system
XcfCFBP6988P_05900	COG4795	General secretion pathway protein
XcfCFBP6988P_05930	COG3250	beta-galactosidase activity
XcfCFBP6988P_05945	COG2188	Transcriptional regulator
XcfCFBP6988P_05955	COG1609	Transcriptional regulator
XcfCFBP6988P_05960	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XcfCFBP6988P_05965	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
XcfCFBP6988P_05980	COG0617	tRNA 3'-terminal CCA addition
XcfCFBP6988P_05985	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
XcfCFBP6988P_05990	COG1012	belongs to the aldehyde dehydrogenase family
XcfCFBP6988P_05995	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
XcfCFBP6988P_06010	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XcfCFBP6988P_06025	COG0218	Necessary for normal cell division and for the maintenance of normal septation
XcfCFBP6988P_06030	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XcfCFBP6988P_06050	COG2205	protein histidine kinase activity
XcfCFBP6988P_06080	COG3791	Glutathione-dependent formaldehyde-activating
XcfCFBP6988P_06095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XcfCFBP6988P_06105	COG0697	spore germination
XcfCFBP6988P_06115	COG0488	(ABC) transporter
XcfCFBP6988P_06125	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
XcfCFBP6988P_06130	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
XcfCFBP6988P_06140	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XcfCFBP6988P_06140	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XcfCFBP6988P_06160	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
XcfCFBP6988P_06165	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XcfCFBP6988P_06170	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
XcfCFBP6988P_06200	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
XcfCFBP6988P_06205	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
XcfCFBP6988P_06210	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
XcfCFBP6988P_06215	COG2205	protein histidine kinase activity
XcfCFBP6988P_06220	COG0745	RESPONSE REGULATOR receiver
XcfCFBP6988P_06235	COG0277	FAD linked oxidase domain protein
XcfCFBP6988P_06240	COG1988	membrane-bound metal-dependent
XcfCFBP6988P_06245	COG0792	nuclease activity
XcfCFBP6988P_06280	COG0275	rRNA processing
XcfCFBP6988P_06285	COG3116	cell division
XcfCFBP6988P_06300	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
XcfCFBP6988P_06305	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
XcfCFBP6988P_06310	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XcfCFBP6988P_06320	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
XcfCFBP6988P_06325	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XcfCFBP6988P_06330	COG1181	Belongs to the D-alanine--D-alanine ligase family
XcfCFBP6988P_06335	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
XcfCFBP6988P_06350	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
XcfCFBP6988P_06360	COG0739	heme binding
XcfCFBP6988P_06365	COG0653	protein targeting
XcfCFBP6988P_06370	COG0494	nUDIX hydrolase
XcfCFBP6988P_06380	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XcfCFBP6988P_06395	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6988P_06395	COG0604	alcohol dehydrogenase
XcfCFBP6988P_06395	COG3321	synthase
XcfCFBP6988P_06415	COG0366	Alpha amylase catalytic
XcfCFBP6988P_06450	COG2226	methyltransferase
XcfCFBP6988P_06455	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
XcfCFBP6988P_06465	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
XcfCFBP6988P_06505	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
XcfCFBP6988P_06515	COG4106	trans-aconitate 2-methyltransferase activity
XcfCFBP6988P_06520	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XcfCFBP6988P_06530	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XcfCFBP6988P_06535	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
XcfCFBP6988P_06545	COG0667	Aldo Keto reductase
XcfCFBP6988P_06555	COG4771	TonB-dependent receptor
XcfCFBP6988P_06575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XcfCFBP6988P_06580	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
XcfCFBP6988P_06590	COG2175	clavaminate synthase activity
XcfCFBP6988P_06600	COG4181	ATPase activity
XcfCFBP6988P_06615	COG0642	Histidine kinase
XcfCFBP6988P_06625	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
XcfCFBP6988P_06645	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
XcfCFBP6988P_06650	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
XcfCFBP6988P_06665	COG3829	transcription factor binding
XcfCFBP6988P_06675	COG1116	anion transmembrane transporter activity
XcfCFBP6988P_06680	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XcfCFBP6988P_06690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XcfCFBP6988P_06695	COG0431	NADPH-dependent FMN reductase
XcfCFBP6988P_06715	COG0747	negative chemotaxis
XcfCFBP6988P_06725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XcfCFBP6988P_06735	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
XcfCFBP6988P_06740	COG2967	ApaG domain
XcfCFBP6988P_06745	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
XcfCFBP6988P_06750	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
XcfCFBP6988P_06755	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XcfCFBP6988P_06760	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
XcfCFBP6988P_06775	COG0123	including yeast histone deacetylase and acetoin utilization protein
XcfCFBP6988P_06780	COG2096	Adenosyltransferase
XcfCFBP6988P_06795	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XcfCFBP6988P_06800	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XcfCFBP6988P_06830	COG3384	dioxygenase
XcfCFBP6988P_06835	COG0583	DNA-binding transcription factor activity
XcfCFBP6988P_06850	COG1024	Enoyl-CoA hydratase
XcfCFBP6988P_06880	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
XcfCFBP6988P_06905	COG0697	spore germination
XcfCFBP6988P_06915	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XcfCFBP6988P_06945	COG2197	response regulator
XcfCFBP6988P_06955	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XcfCFBP6988P_06965	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
XcfCFBP6988P_06970	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XcfCFBP6988P_06980	COG0583	DNA-binding transcription factor activity
XcfCFBP6988P_06985	COG3634	alkyl hydroperoxide reductase activity
XcfCFBP6988P_06995	COG2890	protein-(glutamine-N5) methyltransferase activity
XcfCFBP6988P_07025	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XcfCFBP6988P_07025	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XcfCFBP6988P_07055	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
XcfCFBP6988P_07095	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XcfCFBP6988P_07105	COG1404	Belongs to the peptidase S8 family
XcfCFBP6988P_07110	COG1404	Belongs to the peptidase S8 family
XcfCFBP6988P_07115	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
XcfCFBP6988P_07140	COG1295	ribonuclease BN
XcfCFBP6988P_07145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XcfCFBP6988P_07150	COG1254	Belongs to the acylphosphatase family
XcfCFBP6988P_07165	COG0521	Mo-molybdopterin cofactor biosynthetic process
XcfCFBP6988P_07175	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
XcfCFBP6988P_07180	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
XcfCFBP6988P_07190	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
XcfCFBP6988P_07195	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
XcfCFBP6988P_07205	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
XcfCFBP6988P_07210	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
XcfCFBP6988P_07215	COG0193	aminoacyl-tRNA hydrolase activity
XcfCFBP6988P_07220	COG0012	GTP binding
XcfCFBP6988P_07240	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XcfCFBP6988P_07255	COG0250	Participates in transcription elongation, termination and antitermination
XcfCFBP6988P_07260	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
XcfCFBP6988P_07265	COG0081	regulation of translation
XcfCFBP6988P_07270	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
XcfCFBP6988P_07275	COG0222	ribosome binding
XcfCFBP6988P_07280	COG0085	RNA polymerase activity
XcfCFBP6988P_07285	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
XcfCFBP6988P_07290	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
XcfCFBP6988P_07295	COG0049	tRNA binding
XcfCFBP6988P_07300	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
XcfCFBP6988P_07305	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XcfCFBP6988P_07310	COG0051	transcription antitermination factor activity, RNA binding
XcfCFBP6988P_07315	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
XcfCFBP6988P_07320	COG0088	Forms part of the polypeptide exit tunnel
XcfCFBP6988P_07325	COG0089	rRNA binding
XcfCFBP6988P_07330	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XcfCFBP6988P_07335	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
XcfCFBP6988P_07345	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
XcfCFBP6988P_07350	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
XcfCFBP6988P_07355	COG0255	Belongs to the universal ribosomal protein uL29 family
XcfCFBP6988P_07360	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
XcfCFBP6988P_07370	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
XcfCFBP6988P_07375	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
XcfCFBP6988P_07380	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
XcfCFBP6988P_07385	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
XcfCFBP6988P_07390	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
XcfCFBP6988P_07395	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
XcfCFBP6988P_07405	COG1841	ribosomal large subunit assembly
XcfCFBP6988P_07410	COG0200	Binds to the 23S rRNA
XcfCFBP6988P_07415	COG0201	protein transport
XcfCFBP6988P_07440	COG0203	ribosomal protein L17
XcfCFBP6988P_07445	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
XcfCFBP6988P_07465	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
XcfCFBP6988P_07480	COG0154	amidase activity
XcfCFBP6988P_07490	COG1217	gtp-binding protein TYPA
XcfCFBP6988P_07495	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XcfCFBP6988P_07500	COG0039	L-malate dehydrogenase activity
XcfCFBP6988P_07505	COG0625	glutathione transferase activity
XcfCFBP6988P_07520	COG0446	pyridine nucleotide-disulphide oxidoreductase
XcfCFBP6988P_07520	COG1902	pentaerythritol trinitrate reductase activity
XcfCFBP6988P_07525	COG0604	alcohol dehydrogenase
XcfCFBP6988P_07555	COG0156	8-amino-7-oxononanoate synthase activity
XcfCFBP6988P_07560	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
XcfCFBP6988P_07565	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
XcfCFBP6988P_07570	COG4208	sulfate ABC transporter
XcfCFBP6988P_07575	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
XcfCFBP6988P_07605	COG0406	alpha-ribazole phosphatase activity
XcfCFBP6988P_07610	COG0285	dihydrofolate synthase activity
XcfCFBP6988P_07630	COG2833	Protein of unknown function (DUF455)
XcfCFBP6988P_07640	COG3291	Pkd domain containing protein
XcfCFBP6988P_07650	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XcfCFBP6988P_07655	COG0671	phosphoesterase, PA-phosphatase related
XcfCFBP6988P_07660	COG0438	transferase activity, transferring glycosyl groups
XcfCFBP6988P_07670	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
XcfCFBP6988P_07685	COG4783	chaperone-mediated protein folding
XcfCFBP6988P_07700	COG0473	3-isopropylmalate dehydrogenase activity
XcfCFBP6988P_07795	COG3328	transposase activity
XcfCFBP6988P_07925	COG3179	chitinase
XcfCFBP6988P_07970	COG4695	Portal protein
XcfCFBP6988P_08000	COG3328	transposase activity
XcfCFBP6988P_08015	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
XcfCFBP6988P_08040	COG3852	Histidine kinase
XcfCFBP6988P_08050	COG0544	peptidyl-prolyl cis-trans isomerase activity
XcfCFBP6988P_08060	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
XcfCFBP6988P_08090	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XcfCFBP6988P_08100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XcfCFBP6988P_08110	COG0328	RNA-DNA hybrid ribonuclease activity
XcfCFBP6988P_08115	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XcfCFBP6988P_08120	COG0631	protein serine/threonine phosphatase activity
XcfCFBP6988P_08135	COG0859	PFAM glycosyl transferase family 9
XcfCFBP6988P_08140	COG3642	lipopolysaccharide core region biosynthetic process
XcfCFBP6988P_08145	COG1234	tRNA 3'-trailer cleavage
XcfCFBP6988P_08150	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
XcfCFBP6988P_08160	COG0315	cyclic pyranopterin monophosphate synthase activity
XcfCFBP6988P_08165	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
XcfCFBP6988P_08170	COG0314	molybdopterin synthase activity
XcfCFBP6988P_08190	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
XcfCFBP6988P_08195	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
XcfCFBP6988P_08200	COG0537	adenosine 5'-monophosphoramidase activity
XcfCFBP6988P_08220	COG0714	Associated with various cellular activities
XcfCFBP6988P_08245	COG0424	maF-like protein
XcfCFBP6988P_08250	COG1399	metal-binding, possibly nucleic acid-binding protein
XcfCFBP6988P_08260	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XcfCFBP6988P_08270	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XcfCFBP6988P_08290	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
XcfCFBP6988P_08295	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XcfCFBP6988P_08320	COG3829	transcription factor binding
XcfCFBP6988P_08365	COG2373	Large extracellular alpha-helical protein
XcfCFBP6988P_08385	COG4953	penicillin-binding protein 1C
XcfCFBP6988P_08395	COG0678	peroxiredoxin activity
XcfCFBP6988P_08415	COG0330	HflC and HflK could
XcfCFBP6988P_08420	COG0330	HflC and HflK could
XcfCFBP6988P_08435	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
XcfCFBP6988P_08440	COG0308	aminopeptidase N
XcfCFBP6988P_08445	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6988P_08450	COG1309	transcriptional regulator
XcfCFBP6988P_08545	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XcfCFBP6988P_08555	COG3387	PFAM Glycoside hydrolase 15-related
XcfCFBP6988P_08560	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6988P_08570	COG3537	Alpha-1,2-mannosidase
XcfCFBP6988P_08575	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6988P_08590	COG0492	ferredoxin-NADP+ reductase activity
XcfCFBP6988P_08620	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XcfCFBP6988P_08625	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XcfCFBP6988P_08630	COG2080	2 iron, 2 sulfur cluster binding
XcfCFBP6988P_08665	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XcfCFBP6988P_08680	COG0587	DNA-directed DNA polymerase activity
XcfCFBP6988P_08695	COG1297	OPT oligopeptide transporter protein
XcfCFBP6988P_08715	COG0823	Involved in the tonB-independent uptake of proteins
XcfCFBP6988P_08715	COG1506	peptidase
XcfCFBP6988P_08730	COG2207	Transcriptional regulator
XcfCFBP6988P_08730	COG1917	Cupin 2, conserved barrel domain protein
XcfCFBP6988P_08755	COG0753	catalase activity
XcfCFBP6988P_08760	COG0656	L-ascorbic acid biosynthetic process
XcfCFBP6988P_08770	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XcfCFBP6988P_08770	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XcfCFBP6988P_08775	COG2814	Major facilitator Superfamily
XcfCFBP6988P_08790	COG2194	sulfuric ester hydrolase activity
XcfCFBP6988P_08805	COG0745	RESPONSE REGULATOR receiver
XcfCFBP6988P_08810	COG0642	Histidine kinase
XcfCFBP6988P_08820	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
XcfCFBP6988P_08825	COG2894	cell division
XcfCFBP6988P_08830	COG0850	regulation of cytokinetic process
XcfCFBP6988P_08845	COG4585	Histidine kinase
XcfCFBP6988P_08850	COG2197	response regulator
XcfCFBP6988P_08865	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
XcfCFBP6988P_08890	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
XcfCFBP6988P_08900	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
XcfCFBP6988P_08920	COG1946	Acyl-CoA thioesterase
XcfCFBP6988P_08935	COG0824	Thioesterase
XcfCFBP6988P_08940	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
XcfCFBP6988P_08945	COG0261	This protein binds to 23S rRNA in the presence of protein L20
XcfCFBP6988P_08950	COG0211	Belongs to the bacterial ribosomal protein bL27 family
XcfCFBP6988P_08955	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
XcfCFBP6988P_08960	COG0268	Binds directly to 16S ribosomal RNA
XcfCFBP6988P_08970	COG0196	riboflavin kinase activity
XcfCFBP6988P_08975	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
XcfCFBP6988P_08980	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
XcfCFBP6988P_08985	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
XcfCFBP6988P_09000	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XcfCFBP6988P_09005	COG1845	cytochrome c oxidase, subunit III
XcfCFBP6988P_09010	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
XcfCFBP6988P_09025	COG3152	Membrane
XcfCFBP6988P_09035	COG2207	Transcriptional regulator
XcfCFBP6988P_09040	COG0326	Molecular chaperone. Has ATPase activity
XcfCFBP6988P_09050	COG1366	Belongs to the anti-sigma-factor antagonist family
XcfCFBP6988P_09055	COG1366	Belongs to the anti-sigma-factor antagonist family
XcfCFBP6988P_09060	COG2172	sigma factor antagonist activity
XcfCFBP6988P_09085	COG4771	TonB-dependent receptor
XcfCFBP6988P_09095	COG5507	3-demethylubiquinone-9 3-methyltransferase
XcfCFBP6988P_09100	COG2205	protein histidine kinase activity
XcfCFBP6988P_09110	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XcfCFBP6988P_09115	COG2205	protein histidine kinase activity
XcfCFBP6988P_09115	COG3850	Histidine kinase
XcfCFBP6988P_09115	COG4999	Histidine kinase
XcfCFBP6988P_09115	COG3437	response regulator, receiver
XcfCFBP6988P_09120	COG0784	Response regulator, receiver
XcfCFBP6988P_09120	COG4191	Histidine kinase
XcfCFBP6988P_09145	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XcfCFBP6988P_09155	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XcfCFBP6988P_09165	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XcfCFBP6988P_09170	COG0228	four-way junction DNA binding
XcfCFBP6988P_09175	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
XcfCFBP6988P_09180	COG0336	Belongs to the RNA methyltransferase TrmD family
XcfCFBP6988P_09185	COG0335	large ribosomal subunit rRNA binding
XcfCFBP6988P_09190	COG0534	Mate efflux family protein
XcfCFBP6988P_09215	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
XcfCFBP6988P_09225	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
XcfCFBP6988P_09260	COG3250	beta-galactosidase activity
XcfCFBP6988P_09265	COG3867	Arabinogalactan endo-beta-1,4-galactanase
XcfCFBP6988P_09285	COG1960	acyl-CoA dehydrogenase activity
XcfCFBP6988P_09290	COG1024	Enoyl-CoA hydratase
XcfCFBP6988P_09320	COG1250	3-hydroxyacyl-CoA dehydrogenase
XcfCFBP6988P_09320	COG1024	Enoyl-CoA hydratase
XcfCFBP6988P_09335	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XcfCFBP6988P_09345	COG0481	GTPase activity
XcfCFBP6988P_09360	COG0571	ribonuclease III activity
XcfCFBP6988P_09365	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
XcfCFBP6988P_09370	COG1381	Involved in DNA repair and RecF pathway recombination
XcfCFBP6988P_09380	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
XcfCFBP6988P_09385	COG2954	triphosphatase activity
XcfCFBP6988P_09390	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
XcfCFBP6988P_09395	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
XcfCFBP6988P_09400	COG3046	protein related to deoxyribodipyrimidine photolyase
XcfCFBP6988P_09405	COG1472	Belongs to the glycosyl hydrolase 3 family
XcfCFBP6988P_09410	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
XcfCFBP6988P_09415	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
XcfCFBP6988P_09420	COG1278	Cold shock
XcfCFBP6988P_09425	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XcfCFBP6988P_09435	COG1201	RNA secondary structure unwinding
XcfCFBP6988P_09440	COG1793	dna ligase
XcfCFBP6988P_09450	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XcfCFBP6988P_09450	COG1793	dna ligase
XcfCFBP6988P_09485	COG0183	Belongs to the thiolase family
XcfCFBP6988P_09505	COG1451	nucleotide metabolic process
XcfCFBP6988P_09510	COG5487	UPF0391 membrane protein
XcfCFBP6988P_09520	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XcfCFBP6988P_09535	COG1077	Cell shape determining protein MreB Mrl
XcfCFBP6988P_09540	COG1047	Peptidyl-prolyl cis-trans
XcfCFBP6988P_09550	COG2824	Alkylphosphonate utilization operon protein PhnA
XcfCFBP6988P_09560	COG1902	pentaerythritol trinitrate reductase activity
XcfCFBP6988P_09565	COG2814	Major facilitator Superfamily
XcfCFBP6988P_09595	COG0392	lysyltransferase activity
XcfCFBP6988P_09595	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
XcfCFBP6988P_09605	COG0251	oxidation-reduction process
XcfCFBP6988P_09610	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XcfCFBP6988P_09625	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XcfCFBP6988P_09650	COG1595	DNA-templated transcription, initiation
XcfCFBP6988P_09675	COG2878	Part of a membrane complex involved in electron transport
XcfCFBP6988P_09685	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XcfCFBP6988P_09685	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XcfCFBP6988P_09700	COG1131	(ABC) transporter
XcfCFBP6988P_09705	COG0346	lactoylglutathione lyase activity
XcfCFBP6988P_09710	COG0833	amino acid
XcfCFBP6988P_09715	COG2040	homocysteine
XcfCFBP6988P_09725	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XcfCFBP6988P_09745	COG1695	Transcriptional regulator
XcfCFBP6988P_09765	COG1981	membrane
XcfCFBP6988P_09780	COG0825	malonyl-CoA metabolic process
XcfCFBP6988P_09795	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XcfCFBP6988P_09800	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XcfCFBP6988P_09805	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XcfCFBP6988P_09810	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XcfCFBP6988P_09825	COG0750	zinc metalloprotease
XcfCFBP6988P_09830	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
XcfCFBP6988P_09835	COG0575	Belongs to the CDS family
XcfCFBP6988P_09840	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
XcfCFBP6988P_09845	COG0233	cytoplasmic translational termination
XcfCFBP6988P_09850	COG0528	UMP kinase activity
XcfCFBP6988P_09860	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
XcfCFBP6988P_09865	COG0052	Belongs to the universal ribosomal protein uS2 family
XcfCFBP6988P_09905	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
XcfCFBP6988P_09915	COG1393	Belongs to the ArsC family
XcfCFBP6988P_09920	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XcfCFBP6988P_09925	COG0367	asparagine synthase
XcfCFBP6988P_09935	COG4774	siderophore transport
XcfCFBP6988P_10020	COG4397	Mu-like prophage major head subunit gpT
XcfCFBP6988P_10040	COG2369	cell adhesion
XcfCFBP6988P_10045	COG4383	Mu-like prophage protein gp29
XcfCFBP6988P_10050	COG4373	Mu-like prophage FluMu protein gp28
XcfCFBP6988P_10070	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XcfCFBP6988P_10095	COG5566	PFAM Mor transcription activator
XcfCFBP6988P_10160	COG2842	Transposition protein
XcfCFBP6988P_10165	COG2801	Transposase and inactivated derivatives
XcfCFBP6988P_10205	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
XcfCFBP6988P_10235	COG1566	PFAM secretion protein HlyD family protein
XcfCFBP6988P_10240	COG2814	Major facilitator Superfamily
XcfCFBP6988P_10290	COG0339	signal peptide processing
XcfCFBP6988P_10300	COG0386	Belongs to the glutathione peroxidase family
XcfCFBP6988P_10355	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
XcfCFBP6988P_10360	COG0084	hydrolase, TatD family'
XcfCFBP6988P_10375	COG1960	acyl-CoA dehydrogenase activity
XcfCFBP6988P_10395	COG0367	asparagine synthase
XcfCFBP6988P_10405	COG0305	Participates in initiation and elongation during chromosome replication
XcfCFBP6988P_10410	COG0415	Belongs to the DNA photolyase family
XcfCFBP6988P_10420	COG0583	DNA-binding transcription factor activity
XcfCFBP6988P_10465	COG3706	GGDEF domain
XcfCFBP6988P_10660	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
XcfCFBP6988P_10675	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XcfCFBP6988P_10685	COG0497	DNA recombination
XcfCFBP6988P_10690	COG1420	regulation of RNA biosynthetic process
XcfCFBP6988P_10695	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XcfCFBP6988P_10700	COG0443	Heat shock 70 kDa protein
XcfCFBP6988P_10705	COG0484	heat shock protein binding
XcfCFBP6988P_10715	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
XcfCFBP6988P_10745	COG0583	DNA-binding transcription factor activity
XcfCFBP6988P_10750	COG1132	(ABC) transporter
XcfCFBP6988P_10775	COG0567	Dehydrogenase, E1 component
XcfCFBP6988P_10785	COG2850	peptidyl-arginine hydroxylation
XcfCFBP6988P_10810	COG1253	flavin adenine dinucleotide binding
XcfCFBP6988P_10845	COG1131	(ABC) transporter
XcfCFBP6988P_10850	COG1725	Transcriptional regulator
XcfCFBP6988P_10860	COG0386	Belongs to the glutathione peroxidase family
XcfCFBP6988P_10875	COG2900	Belongs to the SlyX family
XcfCFBP6988P_10900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XcfCFBP6988P_10910	COG0646	methionine synthase
XcfCFBP6988P_10910	COG1410	methionine synthase
XcfCFBP6988P_10915	COG1410	methionine synthase
XcfCFBP6988P_10915	COG0646	methionine synthase
XcfCFBP6988P_10920	COG2226	methyltransferase
XcfCFBP6988P_10925	COG1960	acyl-CoA dehydrogenase activity
XcfCFBP6988P_10935	COG1960	acyl-CoA dehydrogenase activity
XcfCFBP6988P_10965	COG0557	exoribonuclease II activity
XcfCFBP6988P_10975	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XcfCFBP6988P_10985	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XcfCFBP6988P_10995	COG0704	Plays a role in the regulation of phosphate uptake
XcfCFBP6988P_11000	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
XcfCFBP6988P_11005	COG0581	inorganic phosphate transmembrane transporter activity
XcfCFBP6988P_11010	COG0573	inorganic phosphate transmembrane transporter activity
XcfCFBP6988P_11015	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XcfCFBP6988P_11040	COG0659	secondary active sulfate transmembrane transporter activity
XcfCFBP6988P_11045	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
XcfCFBP6988P_11055	COG1024	Enoyl-CoA hydratase
XcfCFBP6988P_11065	COG0494	nUDIX hydrolase
XcfCFBP6988P_11110	COG0116	Belongs to the methyltransferase superfamily
XcfCFBP6988P_11110	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XcfCFBP6988P_11115	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
XcfCFBP6988P_11135	COG2925	Exonuclease
XcfCFBP6988P_11140	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XcfCFBP6988P_11145	COG3844	kynureninase activity
XcfCFBP6988P_11155	COG0662	Cupin 2, conserved barrel domain protein
XcfCFBP6988P_11160	COG0288	reversible hydration of carbon dioxide
XcfCFBP6988P_11240	COG0017	Asparaginyl-tRNA synthetase
XcfCFBP6988P_11250	COG0316	Belongs to the HesB IscA family
XcfCFBP6988P_11255	COG0360	Binds together with S18 to 16S ribosomal RNA
XcfCFBP6988P_11260	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
XcfCFBP6988P_11265	COG0359	binds to the 23S rRNA
XcfCFBP6988P_11280	COG3115	cell septum assembly
XcfCFBP6988P_11290	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XcfCFBP6988P_11295	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
XcfCFBP6988P_11300	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
XcfCFBP6988P_11315	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
XcfCFBP6988P_11325	COG4993	Dehydrogenase
XcfCFBP6988P_11335	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
XcfCFBP6988P_11345	COG2986	histidine ammonia-lyase
XcfCFBP6988P_11350	COG1228	amidohydrolase
XcfCFBP6988P_11390	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
XcfCFBP6988P_11395	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XcfCFBP6988P_11400	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
XcfCFBP6988P_11405	COG1605	Chorismate mutase
XcfCFBP6988P_11405	COG0077	Prephenate dehydratase
XcfCFBP6988P_11410	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
XcfCFBP6988P_11425	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
XcfCFBP6988P_11430	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XcfCFBP6988P_11435	COG0583	DNA-binding transcription factor activity
XcfCFBP6988P_11450	COG0840	transmembrane signaling receptor activity
XcfCFBP6988P_11480	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
XcfCFBP6988P_11485	COG4191	Histidine kinase
XcfCFBP6988P_11485	COG0784	Response regulator, receiver
XcfCFBP6988P_11500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XcfCFBP6988P_11510	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
XcfCFBP6988P_11520	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XcfCFBP6988P_11535	COG1595	DNA-templated transcription, initiation
XcfCFBP6988P_11590	COG2244	polysaccharide biosynthetic process
XcfCFBP6988P_11620	COG2264	protein methyltransferase activity
XcfCFBP6988P_11645	COG1136	(ABC) transporter
XcfCFBP6988P_11655	COG0477	Major facilitator Superfamily
XcfCFBP6988P_11660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XcfCFBP6988P_11675	COG1253	flavin adenine dinucleotide binding
XcfCFBP6988P_11690	COG0306	phosphate transporter
XcfCFBP6988P_11715	COG0504	CTP synthase activity
XcfCFBP6988P_11730	COG0148	phosphopyruvate hydratase activity
XcfCFBP6988P_11735	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
XcfCFBP6988P_11740	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
XcfCFBP6988P_11745	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
XcfCFBP6988P_11750	COG0585	pseudouridine synthase activity
XcfCFBP6988P_11755	COG2840	Smr protein MutS2
XcfCFBP6988P_11760	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
XcfCFBP6988P_11765	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XcfCFBP6988P_11770	COG1238	metal cluster binding
XcfCFBP6988P_11785	COG1534	Rna-binding protein
XcfCFBP6988P_11790	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
XcfCFBP6988P_11800	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
XcfCFBP6988P_11805	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
XcfCFBP6988P_11815	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
XcfCFBP6988P_11820	COG1546	Belongs to the CinA family
XcfCFBP6988P_11830	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XcfCFBP6988P_11835	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
XcfCFBP6988P_11845	COG2137	regulation of response to DNA damage stimulus
XcfCFBP6988P_11850	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
XcfCFBP6988P_11855	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
XcfCFBP6988P_11880	COG1741	Belongs to the pirin family
XcfCFBP6988P_11885	COG0583	DNA-binding transcription factor activity
XcfCFBP6988P_11910	COG0351	phosphomethylpyrimidine kinase
XcfCFBP6988P_11925	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
XcfCFBP6988P_11930	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XcfCFBP6988P_11945	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XcfCFBP6988P_11955	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
XcfCFBP6988P_11960	COG3734	2-keto-3-deoxy-galactonokinase
XcfCFBP6988P_11970	COG4948	Mandelate Racemase Muconate Lactonizing
XcfCFBP6988P_11975	COG0800	Aldolase
XcfCFBP6988P_12015	COG1501	Belongs to the glycosyl hydrolase 31 family
XcfCFBP6988P_12025	COG1070	Carbohydrate kinase
XcfCFBP6988P_12030	COG2115	Belongs to the xylose isomerase family
XcfCFBP6988P_12035	COG0477	Major facilitator Superfamily
XcfCFBP6988P_12050	COG0860	N-Acetylmuramoyl-L-alanine amidase
XcfCFBP6988P_12055	COG1469	GTP cyclohydrolase I activity
XcfCFBP6988P_12075	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
XcfCFBP6988P_12080	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
XcfCFBP6988P_12085	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
XcfCFBP6988P_12110	COG1472	Belongs to the glycosyl hydrolase 3 family
XcfCFBP6988P_12125	COG2203	Gaf domain
XcfCFBP6988P_12125	COG4251	negative regulation of phosphorylation
XcfCFBP6988P_12125	COG5001	Diguanylate cyclase
XcfCFBP6988P_12125	COG3706	GGDEF domain
XcfCFBP6988P_12130	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XcfCFBP6988P_12135	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
XcfCFBP6988P_12145	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
XcfCFBP6988P_12150	COG0671	phosphoesterase, PA-phosphatase related
XcfCFBP6988P_12165	COG1794	racemase activity, acting on amino acids and derivatives
XcfCFBP6988P_12175	COG0697	spore germination
XcfCFBP6988P_12180	COG0812	UDP-N-acetylmuramate dehydrogenase activity
XcfCFBP6988P_12185	COG0167	dihydroorotate dehydrogenase activity
XcfCFBP6988P_12205	COG1012	belongs to the aldehyde dehydrogenase family
XcfCFBP6988P_12245	COG1215	transferase activity, transferring glycosyl groups
XcfCFBP6988P_12250	COG0726	polysaccharide deacetylase
XcfCFBP6988P_12250	COG1649	PFAM Uncharacterised BCR, COG1649
XcfCFBP6988P_12280	COG3328	transposase activity
XcfCFBP6988P_12310	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
XcfCFBP6988P_12320	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XcfCFBP6988P_12325	COG0124	histidyl-tRNA synthetase
XcfCFBP6988P_12335	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
XcfCFBP6988P_12340	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
XcfCFBP6988P_12345	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XcfCFBP6988P_12350	COG0131	Imidazoleglycerol-phosphate dehydratase
XcfCFBP6988P_12350	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
XcfCFBP6988P_12355	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
XcfCFBP6988P_12360	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
XcfCFBP6988P_12365	COG0107	imidazoleglycerol-phosphate synthase activity
XcfCFBP6988P_12370	COG0140	phosphoribosyl-ATP diphosphatase activity
XcfCFBP6988P_12370	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
XcfCFBP6988P_12385	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
XcfCFBP6988P_12390	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
XcfCFBP6988P_12395	COG0235	Class ii aldolase
XcfCFBP6988P_12400	COG0531	amino acid
XcfCFBP6988P_12405	COG0531	amino acid
XcfCFBP6988P_12415	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XcfCFBP6988P_12420	COG0277	FAD linked oxidase domain protein
XcfCFBP6988P_12440	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XcfCFBP6988P_12485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XcfCFBP6988P_12495	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
XcfCFBP6988P_12500	COG0505	Belongs to the CarA family
XcfCFBP6988P_12510	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
XcfCFBP6988P_12515	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XcfCFBP6988P_12525	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
XcfCFBP6988P_12535	COG3279	Response regulator of the LytR AlgR family
XcfCFBP6988P_12545	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
XcfCFBP6988P_12555	COG2198	Histidine kinase
XcfCFBP6988P_12555	COG0784	Response regulator, receiver
XcfCFBP6988P_12555	COG2205	protein histidine kinase activity
XcfCFBP6988P_12560	COG2198	Histidine kinase
XcfCFBP6988P_12560	COG2205	protein histidine kinase activity
XcfCFBP6988P_12560	COG0784	Response regulator, receiver
XcfCFBP6988P_12565	COG1024	Enoyl-CoA hydratase
XcfCFBP6988P_12570	COG0318	PFAM AMP-dependent synthetase and ligase
XcfCFBP6988P_12605	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XcfCFBP6988P_12615	COG2201	protein-glutamate methylesterase activity
XcfCFBP6988P_12620	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
XcfCFBP6988P_12630	COG0840	transmembrane signaling receptor activity
XcfCFBP6988P_12645	COG0835	chemotaxis
XcfCFBP6988P_12670	COG0840	transmembrane signaling receptor activity
XcfCFBP6988P_12675	COG0840	transmembrane signaling receptor activity
XcfCFBP6988P_12685	COG0840	transmembrane signaling receptor activity
XcfCFBP6988P_12695	COG0840	transmembrane signaling receptor activity
XcfCFBP6988P_12705	COG0840	transmembrane signaling receptor activity
XcfCFBP6988P_12710	COG0840	transmembrane signaling receptor activity
XcfCFBP6988P_12715	COG0840	transmembrane signaling receptor activity
XcfCFBP6988P_12730	COG0840	transmembrane signaling receptor activity
XcfCFBP6988P_12755	COG0745	RESPONSE REGULATOR receiver
XcfCFBP6988P_12765	COG0835	chemotaxis
XcfCFBP6988P_12775	COG1360	Flagellar Motor Protein
XcfCFBP6988P_12780	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
XcfCFBP6988P_12800	COG1192	Involved in chromosome partitioning
XcfCFBP6988P_12865	COG0643	Histidine kinase
XcfCFBP6988P_12865	COG2198	Histidine kinase
XcfCFBP6988P_12865	COG0784	Response regulator, receiver
XcfCFBP6988P_12925	COG1684	flagellar biosynthetic protein fliR
XcfCFBP6988P_12945	COG3190	flagellar
XcfCFBP6988P_12995	COG1677	Flagellar hook-basal body complex protein FliE
XcfCFBP6988P_13030	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6988P_13035	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6988P_13040	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XcfCFBP6988P_13060	COG2201	protein-glutamate methylesterase activity
XcfCFBP6988P_13090	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
XcfCFBP6988P_13100	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XcfCFBP6988P_13110	COG1705	Flagellar rod assembly protein muramidase FlgJ
XcfCFBP6988P_13110	COG3951	Flagellar rod assembly protein muramidase FlgJ
XcfCFBP6988P_13115	COG1706	bacterial-type flagellum-dependent cell motility
XcfCFBP6988P_13120	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
XcfCFBP6988P_13130	COG4787	bacterial-type flagellum-dependent cell motility
XcfCFBP6988P_13140	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
XcfCFBP6988P_13145	COG1558	bacterial-type flagellum-dependent cell motility
XcfCFBP6988P_13155	COG0835	chemotaxis
XcfCFBP6988P_13155	COG0784	Response regulator, receiver
XcfCFBP6988P_13175	COG5002	protein histidine kinase activity
XcfCFBP6988P_13205	COG2915	High frequency lysogenization protein hflD homolog
XcfCFBP6988P_13210	COG0482	sulfurtransferase activity
XcfCFBP6988P_13225	COG0542	response to heat
XcfCFBP6988P_13235	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
XcfCFBP6988P_13245	COG0492	ferredoxin-NADP+ reductase activity
XcfCFBP6988P_13250	COG1674	ftsk spoiiie
XcfCFBP6988P_13260	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
XcfCFBP6988P_13270	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
XcfCFBP6988P_13275	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
XcfCFBP6988P_13285	COG0183	Belongs to the thiolase family
XcfCFBP6988P_13290	COG1024	Enoyl-CoA hydratase
XcfCFBP6988P_13290	COG1250	3-hydroxyacyl-CoA dehydrogenase
XcfCFBP6988P_13305	COG0820	rRNA (adenine-C2-)-methyltransferase activity
XcfCFBP6988P_13315	COG1426	Protein conserved in bacteria
XcfCFBP6988P_13325	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XcfCFBP6988P_13330	COG1160	GTP binding
XcfCFBP6988P_13335	COG0303	'Molybdopterin
XcfCFBP6988P_13340	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XcfCFBP6988P_13375	COG0708	Exodeoxyribonuclease III
XcfCFBP6988P_13385	COG0303	'Molybdopterin
XcfCFBP6988P_13390	COG0746	molybdenum cofactor guanylyltransferase activity
XcfCFBP6988P_13420	COG1914	H( )-stimulated, divalent metal cation uptake system
XcfCFBP6988P_13435	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
XcfCFBP6988P_13440	COG0668	transmembrane transport
XcfCFBP6988P_13450	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
XcfCFBP6988P_13465	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6988P_13470	COG1183	phosphatidylcholine synthase activity
XcfCFBP6988P_13480	COG3243	poly(R)-hydroxyalkanoic acid synthase
XcfCFBP6988P_13495	COG0723	plastoquinol--plastocyanin reductase activity
XcfCFBP6988P_13495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XcfCFBP6988P_13505	COG2183	response to ionizing radiation
XcfCFBP6988P_13510	COG0784	Response regulator, receiver
XcfCFBP6988P_13510	COG2205	protein histidine kinase activity
XcfCFBP6988P_13565	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcfCFBP6988P_13575	COG0800	Aldolase
XcfCFBP6988P_13580	COG0129	dihydroxy-acid dehydratase activity
XcfCFBP6988P_13585	COG0363	glucosamine-6-phosphate deaminase activity
XcfCFBP6988P_13590	COG0837	glucose binding
XcfCFBP6988P_13595	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XcfCFBP6988P_13605	COG0354	folic acid binding
XcfCFBP6988P_13620	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
XcfCFBP6988P_13635	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
XcfCFBP6988P_13640	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
XcfCFBP6988P_13650	COG4591	ABC-type transport system involved in lipoprotein release permease component
XcfCFBP6988P_13655	COG1136	(ABC) transporter
XcfCFBP6988P_13670	COG0811	peptide transport
XcfCFBP6988P_13675	COG0848	biopolymer transport protein
XcfCFBP6988P_13680	COG1132	(ABC) transporter
XcfCFBP6988P_13685	COG1663	tetraacyldisaccharide 4'-kinase activity
XcfCFBP6988P_13690	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
XcfCFBP6988P_13695	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
XcfCFBP6988P_13705	COG0322	excinuclease ABC activity
XcfCFBP6988P_13710	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XcfCFBP6988P_13735	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
XcfCFBP6988P_13755	COG1054	Belongs to the UPF0176 family
XcfCFBP6988P_13765	COG1530	ribonuclease E activity
XcfCFBP6988P_13775	COG3064	Membrane
XcfCFBP6988P_13780	COG0428	transporter
XcfCFBP6988P_13790	COG2154	pterin-4-alpha-carbinolamine dehydratase
XcfCFBP6988P_13795	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
XcfCFBP6988P_13795	COG0316	Belongs to the HesB IscA family
XcfCFBP6988P_13845	COG2226	methyltransferase
XcfCFBP6988P_13845	COG1073	alpha beta
XcfCFBP6988P_13850	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
XcfCFBP6988P_13855	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6988P_13865	COG5599	Phosphatase
XcfCFBP6988P_13910	COG2951	lytic endotransglycosylase activity
XcfCFBP6988P_13935	COG3220	belongs to the UPF0276 family
XcfCFBP6988P_13960	COG3920	Histidine kinase
XcfCFBP6988P_13970	COG1238	metal cluster binding
XcfCFBP6988P_14000	COG3279	Response regulator of the LytR AlgR family
XcfCFBP6988P_14045	COG4566	intracellular signal transduction
XcfCFBP6988P_14055	COG5001	Diguanylate cyclase
XcfCFBP6988P_14075	COG3685	Protein conserved in bacteria
XcfCFBP6988P_14095	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XcfCFBP6988P_14095	COG1648	precorrin-2 dehydrogenase activity
XcfCFBP6988P_14110	COG2814	Major facilitator Superfamily
XcfCFBP6988P_14125	COG1335	isochorismatase
XcfCFBP6988P_14140	COG2197	response regulator
XcfCFBP6988P_14155	COG0583	DNA-binding transcription factor activity
XcfCFBP6988P_14160	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XcfCFBP6988P_14165	COG3002	Belongs to the UPF0753 family
XcfCFBP6988P_14170	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XcfCFBP6988P_14170	COG0519	Catalyzes the synthesis of GMP from XMP
XcfCFBP6988P_14180	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
XcfCFBP6988P_14195	COG0475	glutathione-regulated potassium exporter activity
XcfCFBP6988P_14195	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XcfCFBP6988P_14200	COG1210	Utp--glucose-1-phosphate uridylyltransferase
XcfCFBP6988P_14210	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XcfCFBP6988P_14215	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
XcfCFBP6988P_14225	COG0776	regulation of translation
XcfCFBP6988P_14230	COG0539	negative regulation of cytoplasmic translation
XcfCFBP6988P_14235	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
XcfCFBP6988P_14255	COG2957	Belongs to the agmatine deiminase family
XcfCFBP6988P_14260	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XcfCFBP6988P_14285	COG0395	ABC-type sugar transport system, permease component
XcfCFBP6988P_14290	COG1175	transmembrane transport
XcfCFBP6988P_14320	COG2350	Protein conserved in bacteria
XcfCFBP6988P_14325	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
XcfCFBP6988P_14330	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
XcfCFBP6988P_14335	COG1187	pseudouridine synthase activity
XcfCFBP6988P_14355	COG0436	Aminotransferase
XcfCFBP6988P_14360	COG4133	protoheme IX ABC transporter activity
XcfCFBP6988P_14380	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
XcfCFBP6988P_14385	COG1138	Cytochrome C-type biogenesis protein
XcfCFBP6988P_14405	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XcfCFBP6988P_14410	COG1278	Cold shock
XcfCFBP6988P_14415	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
XcfCFBP6988P_14420	COG4988	ABC transporter
XcfCFBP6988P_14430	COG1294	oxidase, subunit
XcfCFBP6988P_14460	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
XcfCFBP6988P_14465	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
XcfCFBP6988P_14475	COG0165	Argininosuccinate lyase
XcfCFBP6988P_14480	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
XcfCFBP6988P_14490	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XcfCFBP6988P_14495	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XcfCFBP6988P_14505	COG0137	argininosuccinate synthase activity
XcfCFBP6988P_14510	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
XcfCFBP6988P_14520	COG0215	cysteine-tRNA ligase activity
XcfCFBP6988P_14525	COG2166	iron-sulfur cluster assembly
XcfCFBP6988P_14540	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
XcfCFBP6988P_14545	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XcfCFBP6988P_14565	COG4302	ethanolamine ammonia-lyase activity
XcfCFBP6988P_14615	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XcfCFBP6988P_14620	COG0402	S-adenosylhomocysteine deaminase activity
XcfCFBP6988P_14630	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XcfCFBP6988P_14640	COG3300	MHYT domain
XcfCFBP6988P_14640	COG5001	Diguanylate cyclase
XcfCFBP6988P_14655	COG0483	inositol monophosphate 1-phosphatase activity
XcfCFBP6988P_14660	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XcfCFBP6988P_14680	COG0488	(ABC) transporter
XcfCFBP6988P_14685	COG0513	Belongs to the DEAD box helicase family
XcfCFBP6988P_14690	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
XcfCFBP6988P_14695	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
XcfCFBP6988P_14705	COG0625	glutathione transferase activity
XcfCFBP6988P_14715	COG4681	YaeQ
XcfCFBP6988P_14720	COG2081	HI0933 family
XcfCFBP6988P_14730	COG0501	Belongs to the peptidase M48B family
XcfCFBP6988P_14735	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XcfCFBP6988P_14740	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6988P_14765	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
XcfCFBP6988P_14770	COG0860	N-Acetylmuramoyl-L-alanine amidase
XcfCFBP6988P_14775	COG0802	atpase or kinase
XcfCFBP6988P_14780	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XcfCFBP6988P_14780	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
XcfCFBP6988P_14785	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XcfCFBP6988P_14790	COG1570	exodeoxyribonuclease VII activity
XcfCFBP6988P_14800	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XcfCFBP6988P_14840	COG0582	viral genome integration into host DNA
XcfCFBP6988P_15025	COG3328	transposase activity
XcfCFBP6988P_15040	COG0305	Participates in initiation and elongation during chromosome replication
XcfCFBP6988P_15125	COG3723	Recombinational DNA repair protein, rece pathway
XcfCFBP6988P_15160	COG0835	chemotaxis
XcfCFBP6988P_15165	COG0840	transmembrane signaling receptor activity
XcfCFBP6988P_15170	COG2094	Belongs to the DNA glycosylase MPG family
XcfCFBP6988P_15175	COG1201	RNA secondary structure unwinding
XcfCFBP6988P_15195	COG2969	positive regulation of protein catabolic process
XcfCFBP6988P_15200	COG0625	glutathione transferase activity
XcfCFBP6988P_15205	COG2857	Cytochrome c1
XcfCFBP6988P_15210	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
XcfCFBP6988P_15215	COG0723	plastoquinol--plastocyanin reductase activity
XcfCFBP6988P_15225	COG0741	lytic transglycosylase activity
XcfCFBP6988P_15240	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XcfCFBP6988P_15245	COG1702	phosphate starvation-inducible protein PhoH
XcfCFBP6988P_15255	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
XcfCFBP6988P_15265	COG4535	Mg2 and Co2 transporter CorC
XcfCFBP6988P_15280	COG1012	belongs to the aldehyde dehydrogenase family
XcfCFBP6988P_15285	COG1177	transmembrane transport
XcfCFBP6988P_15290	COG1176	ABC-type spermidine putrescine transport system, permease component I
XcfCFBP6988P_15300	COG3842	ATPase activity
XcfCFBP6988P_15320	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
XcfCFBP6988P_15340	COG0174	glutamine synthetase
XcfCFBP6988P_15345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XcfCFBP6988P_15355	COG2703	oxygen carrier activity
XcfCFBP6988P_15360	COG0477	Major facilitator Superfamily
XcfCFBP6988P_15375	COG0243	molybdopterin cofactor binding
XcfCFBP6988P_15380	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
XcfCFBP6988P_15385	COG2223	nitrite transmembrane transporter activity
XcfCFBP6988P_15400	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XcfCFBP6988P_15410	COG2733	membrane
XcfCFBP6988P_15415	COG0784	Response regulator, receiver
XcfCFBP6988P_15415	COG2205	protein histidine kinase activity
XcfCFBP6988P_15415	COG5002	protein histidine kinase activity
XcfCFBP6988P_15435	COG0477	Major facilitator Superfamily
XcfCFBP6988P_15440	COG2902	Dehydrogenase
XcfCFBP6988P_15450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcfCFBP6988P_15455	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcfCFBP6988P_15460	COG1609	Transcriptional regulator
XcfCFBP6988P_15465	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
XcfCFBP6988P_15465	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XcfCFBP6988P_15470	COG1105	Belongs to the carbohydrate kinase PfkB family
XcfCFBP6988P_15475	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XcfCFBP6988P_15475	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XcfCFBP6988P_15510	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XcfCFBP6988P_15520	COG1862	Preprotein translocase
XcfCFBP6988P_15525	COG0343	queuine tRNA-ribosyltransferase activity
XcfCFBP6988P_15530	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
XcfCFBP6988P_15565	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
XcfCFBP6988P_15570	COG3291	Pkd domain containing protein
XcfCFBP6988P_15575	COG0405	Gamma-glutamyltransferase
XcfCFBP6988P_15580	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XcfCFBP6988P_15590	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
XcfCFBP6988P_15595	COG0742	ribosomal rna small subunit methyltransferase
XcfCFBP6988P_15600	COG0326	Molecular chaperone. Has ATPase activity
XcfCFBP6988P_15705	COG0531	amino acid
XcfCFBP6988P_15720	COG0006	proline dipeptidase activity
XcfCFBP6988P_15730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XcfCFBP6988P_15745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XcfCFBP6988P_15750	COG3938	Belongs to the proline racemase family
XcfCFBP6988P_15760	COG0552	protein localization to endoplasmic reticulum
XcfCFBP6988P_15770	COG1194	a g-specific adenine glycosylase
XcfCFBP6988P_15775	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
XcfCFBP6988P_15780	COG0784	Response regulator, receiver
XcfCFBP6988P_15780	COG4191	Histidine kinase
XcfCFBP6988P_15795	COG0322	excinuclease ABC activity
XcfCFBP6988P_15810	COG3040	lipid binding
XcfCFBP6988P_15820	COG1960	acyl-CoA dehydrogenase activity
XcfCFBP6988P_15830	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
XcfCFBP6988P_15850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XcfCFBP6988P_15855	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XcfCFBP6988P_15860	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XcfCFBP6988P_15885	COG0438	transferase activity, transferring glycosyl groups
XcfCFBP6988P_15895	COG0438	transferase activity, transferring glycosyl groups
XcfCFBP6988P_15900	COG0438	transferase activity, transferring glycosyl groups
XcfCFBP6988P_15950	COG0072	phenylalanine-tRNA ligase activity
XcfCFBP6988P_15950	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XcfCFBP6988P_15955	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
XcfCFBP6988P_15970	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
XcfCFBP6988P_15975	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
XcfCFBP6988P_15990	COG2211	Major facilitator Superfamily
XcfCFBP6988P_15990	COG2190	(PTS) system
XcfCFBP6988P_16000	COG1082	Xylose isomerase domain protein TIM barrel
XcfCFBP6988P_16015	COG0366	Alpha amylase catalytic
XcfCFBP6988P_16060	COG3702	type iv secretory pathway
XcfCFBP6988P_16080	COG2948	multi-organism process
XcfCFBP6988P_16100	COG3505	Type IV secretory pathway VirD4
XcfCFBP6988P_16110	COG0582	viral genome integration into host DNA
XcfCFBP6988P_16120	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
XcfCFBP6988P_16240	COG0556	nucleotide-excision repair
XcfCFBP6988P_16245	COG4969	Belongs to the N-Me-Phe pilin family
XcfCFBP6988P_16280	COG4969	Belongs to the N-Me-Phe pilin family
XcfCFBP6988P_16285	COG1611	Belongs to the LOG family
XcfCFBP6988P_16300	COG2095	MarC family integral membrane protein
XcfCFBP6988P_16310	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XcfCFBP6988P_16345	COG1185	polyribonucleotide nucleotidyltransferase activity
XcfCFBP6988P_16350	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
XcfCFBP6988P_16355	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
XcfCFBP6988P_16360	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
XcfCFBP6988P_16365	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
XcfCFBP6988P_16370	COG0195	Participates in both transcription termination and antitermination
XcfCFBP6988P_16375	COG0779	Required for maturation of 30S ribosomal subunits
XcfCFBP6988P_16385	COG1007	ATP synthesis coupled electron transport
XcfCFBP6988P_16410	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XcfCFBP6988P_16415	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
XcfCFBP6988P_16425	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XcfCFBP6988P_16430	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
XcfCFBP6988P_16435	COG0649	NAD binding
XcfCFBP6988P_16440	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XcfCFBP6988P_16445	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XcfCFBP6988P_16450	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XcfCFBP6988P_16465	COG0149	triose-phosphate isomerase activity
XcfCFBP6988P_16470	COG0300	oxidoreductase activity
XcfCFBP6988P_16500	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XcfCFBP6988P_16505	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
XcfCFBP6988P_16510	COG0159	tryptophan synthase activity
XcfCFBP6988P_16520	COG0133	tryptophan synthase activity
XcfCFBP6988P_16530	COG0135	phosphoribosylanthranilate isomerase activity
XcfCFBP6988P_16535	COG0101	tRNA pseudouridine synthase activity
XcfCFBP6988P_16555	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XcfCFBP6988P_16560	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XcfCFBP6988P_16565	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
XcfCFBP6988P_16570	COG2890	protein-(glutamine-N5) methyltransferase activity
XcfCFBP6988P_16580	COG0688	phosphatidylethanolamine metabolic process
XcfCFBP6988P_16595	COG0433	COG0433 Predicted ATPase
XcfCFBP6988P_16600	COG0494	nUDIX hydrolase
XcfCFBP6988P_16615	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XcfCFBP6988P_16620	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XcfCFBP6988P_16640	COG0717	Belongs to the dCTP deaminase family
XcfCFBP6988P_16650	COG0489	protein tyrosine kinase activity
XcfCFBP6988P_16670	COG3590	peptidase
XcfCFBP6988P_16675	COG3590	peptidase
XcfCFBP6988P_16695	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XcfCFBP6988P_16700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XcfCFBP6988P_16705	COG2311	Membrane
XcfCFBP6988P_16710	COG1047	Peptidyl-prolyl cis-trans
XcfCFBP6988P_16715	COG0791	NLP P60 protein
XcfCFBP6988P_16720	COG0791	NLP P60 protein
XcfCFBP6988P_16730	COG4106	trans-aconitate 2-methyltransferase activity
XcfCFBP6988P_16735	COG1301	dicarboxylic acid transport
XcfCFBP6988P_16740	COG1785	Belongs to the alkaline phosphatase family
XcfCFBP6988P_16750	COG0037	tRNA processing
XcfCFBP6988P_16755	COG1722	exodeoxyribonuclease VII activity
XcfCFBP6988P_16760	COG0142	geranyltranstransferase activity
XcfCFBP6988P_16765	COG4104	PAAR repeat-containing protein
XcfCFBP6988P_16775	COG0312	modulator of DNA gyrase
XcfCFBP6988P_16780	COG3028	Belongs to the UPF0307 family
XcfCFBP6988P_16785	COG0312	modulator of DNA gyrase
XcfCFBP6988P_16795	COG3164	Protein of unknown function
XcfCFBP6988P_16805	COG0424	maF-like protein
XcfCFBP6988P_16810	COG2968	Membrane
XcfCFBP6988P_16825	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
XcfCFBP6988P_16840	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
XcfCFBP6988P_16855	COG0495	leucyl-tRNA aminoacylation
XcfCFBP6988P_16865	COG3118	belongs to the thioredoxin family
XcfCFBP6988P_16905	COG2155	Conserved Protein
XcfCFBP6988P_16950	COG1132	(ABC) transporter
XcfCFBP6988P_16975	COG1538	Outer membrane efflux protein
XcfCFBP6988P_16980	COG0745	RESPONSE REGULATOR receiver
XcfCFBP6988P_16985	COG5000	phosphorelay sensor kinase activity
XcfCFBP6988P_16985	COG5002	protein histidine kinase activity
XcfCFBP6988P_16990	COG0475	glutathione-regulated potassium exporter activity
XcfCFBP6988P_17000	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XcfCFBP6988P_17025	COG1187	pseudouridine synthase activity
XcfCFBP6988P_17030	COG5001	Diguanylate cyclase
XcfCFBP6988P_17030	COG5002	protein histidine kinase activity
XcfCFBP6988P_17040	COG1595	DNA-templated transcription, initiation
XcfCFBP6988P_17150	COG2951	lytic endotransglycosylase activity
XcfCFBP6988P_17205	COG0667	Aldo Keto reductase
XcfCFBP6988P_17210	COG2814	Major facilitator Superfamily
XcfCFBP6988P_17215	COG0583	DNA-binding transcription factor activity
XcfCFBP6988P_17225	COG2207	Transcriptional regulator
XcfCFBP6988P_17235	COG1309	transcriptional regulator
XcfCFBP6988P_17245	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcfCFBP6988P_17260	COG0735	belongs to the Fur family
XcfCFBP6988P_17265	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XcfCFBP6988P_17290	COG4452	Inner membrane protein CreD
XcfCFBP6988P_17300	COG2205	protein histidine kinase activity
XcfCFBP6988P_17305	COG0745	RESPONSE REGULATOR receiver
XcfCFBP6988P_17310	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
XcfCFBP6988P_17320	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
XcfCFBP6988P_17330	COG0643	Histidine kinase
XcfCFBP6988P_17330	COG2198	Histidine kinase
XcfCFBP6988P_17335	COG0840	transmembrane signaling receptor activity
XcfCFBP6988P_17340	COG0835	chemotaxis
XcfCFBP6988P_17345	COG2202	Pas domain
XcfCFBP6988P_17345	COG2199	diguanylate cyclase activity
XcfCFBP6988P_17345	COG2200	EAL domain
XcfCFBP6988P_17350	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XcfCFBP6988P_17360	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XcfCFBP6988P_17365	COG3590	peptidase
XcfCFBP6988P_17375	COG0588	phosphoglycerate mutase activity
XcfCFBP6988P_17380	COG1515	deoxyribonuclease V activity
XcfCFBP6988P_17390	COG1741	Belongs to the pirin family
XcfCFBP6988P_17405	COG1741	Belongs to the pirin family
XcfCFBP6988P_17410	COG1966	Carbon starvation protein
XcfCFBP6988P_17415	COG2879	small protein
XcfCFBP6988P_17465	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
XcfCFBP6988P_17470	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XcfCFBP6988P_17475	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XcfCFBP6988P_17480	COG2080	2 iron, 2 sulfur cluster binding
XcfCFBP6988P_17485	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6988P_17485	COG3321	synthase
XcfCFBP6988P_17485	COG0604	alcohol dehydrogenase
XcfCFBP6988P_17495	COG0629	single-stranded DNA binding
XcfCFBP6988P_17500	COG0142	geranyltranstransferase activity
XcfCFBP6988P_17515	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
XcfCFBP6988P_17530	COG0527	aspartate kinase activity
XcfCFBP6988P_17535	COG0384	phenazine biosynthesis protein PhzF
XcfCFBP6988P_17540	COG0384	phenazine biosynthesis protein PhzF
XcfCFBP6988P_17550	COG1764	response to oxidative stress
XcfCFBP6988P_17555	COG0540	Belongs to the ATCase OTCase family
XcfCFBP6988P_17560	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
XcfCFBP6988P_17565	COG1678	Uncharacterized ACR, COG1678
XcfCFBP6988P_17575	COG0519	Catalyzes the synthesis of GMP from XMP
XcfCFBP6988P_17605	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
XcfCFBP6988P_17620	COG0739	heme binding
XcfCFBP6988P_17640	COG0693	protein deglycase activity
XcfCFBP6988P_17650	COG1959	2 iron, 2 sulfur cluster binding
XcfCFBP6988P_17655	COG0719	Fe-S assembly protein
XcfCFBP6988P_17660	COG0396	ATPase activity
XcfCFBP6988P_17665	COG0719	Fe-S assembly protein
XcfCFBP6988P_17670	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XcfCFBP6988P_17680	COG2146	nitrite reductase [NAD(P)H] activity
XcfCFBP6988P_17690	COG3128	pkhd-type hydroxylase
XcfCFBP6988P_17715	COG1477	protein flavinylation
XcfCFBP6988P_17720	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XcfCFBP6988P_17730	COG1555	photosystem II stabilization
XcfCFBP6988P_17745	COG3178	'Phosphotransferase
XcfCFBP6988P_17750	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XcfCFBP6988P_17765	COG0628	permease
XcfCFBP6988P_17775	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
XcfCFBP6988P_17785	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
XcfCFBP6988P_17805	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
XcfCFBP6988P_17810	COG0271	Belongs to the BolA IbaG family
XcfCFBP6988P_17820	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
XcfCFBP6988P_17830	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
XcfCFBP6988P_17835	COG1137	ATPase activity
XcfCFBP6988P_17850	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
XcfCFBP6988P_17855	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
XcfCFBP6988P_17860	COG1660	Displays ATPase and GTPase activities
XcfCFBP6988P_17870	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XcfCFBP6988P_17875	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XcfCFBP6988P_17885	COG2239	Acts as a magnesium transporter
XcfCFBP6988P_17895	COG1294	oxidase, subunit
XcfCFBP6988P_17900	COG1271	oxidase subunit
XcfCFBP6988P_17910	COG1113	amino acid transport
XcfCFBP6988P_17940	COG2197	response regulator
XcfCFBP6988P_17945	COG0531	amino acid
XcfCFBP6988P_18055	COG2814	Major facilitator Superfamily
XcfCFBP6988P_18065	COG0754	glutathionylspermidine amidase activity
XcfCFBP6988P_18090	COG1842	Phage shock protein A
XcfCFBP6988P_18100	COG0259	pyridoxamine-phosphate oxidase activity
XcfCFBP6988P_18105	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
XcfCFBP6988P_18110	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
XcfCFBP6988P_18120	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
XcfCFBP6988P_18125	COG2814	Major facilitator Superfamily
XcfCFBP6988P_18145	COG2198	Histidine kinase
XcfCFBP6988P_18145	COG0784	Response regulator, receiver
XcfCFBP6988P_18145	COG2205	protein histidine kinase activity
XcfCFBP6988P_18150	COG2353	YceI-like domain
XcfCFBP6988P_18170	COG1760	l-serine dehydratase
XcfCFBP6988P_18185	COG0460	homoserine dehydrogenase
XcfCFBP6988P_18185	COG0527	aspartate kinase activity
XcfCFBP6988P_18190	COG0626	cystathionine gamma-synthase activity
XcfCFBP6988P_18195	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XcfCFBP6988P_18200	COG0739	heme binding
XcfCFBP6988P_18205	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
XcfCFBP6988P_18210	COG1272	protein, Hemolysin III
XcfCFBP6988P_18215	COG2982	Protein involved in outer membrane biogenesis
XcfCFBP6988P_18220	COG0516	GMP reductase activity
XcfCFBP6988P_18220	COG0517	IMP dehydrogenase activity
XcfCFBP6988P_18225	COG0463	Glycosyl transferase, family 2
XcfCFBP6988P_18230	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XcfCFBP6988P_18235	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
XcfCFBP6988P_18245	COG4771	TonB-dependent receptor
XcfCFBP6988P_18255	COG1309	transcriptional regulator
XcfCFBP6988P_18265	COG1960	acyl-CoA dehydrogenase activity
XcfCFBP6988P_18295	COG0509	glycine decarboxylation via glycine cleavage system
XcfCFBP6988P_18300	COG0404	The glycine cleavage system catalyzes the degradation of glycine
XcfCFBP6988P_18315	COG1742	UPF0060 membrane protein
XcfCFBP6988P_18320	COG3956	TIGRFAM MazG family protein
XcfCFBP6988P_18325	COG1218	3'(2'),5'-bisphosphate nucleotidase
XcfCFBP6988P_18330	COG0494	nUDIX hydrolase
XcfCFBP6988P_18340	COG1385	rRNA (uridine-N3-)-methyltransferase activity
XcfCFBP6988P_18345	COG0837	glucose binding
XcfCFBP6988P_18360	COG1388	LysM domain
XcfCFBP6988P_18360	COG3858	chitin binding
XcfCFBP6988P_18365	COG3525	Glycosyl hydrolase, family 20, catalytic domain
XcfCFBP6988P_18375	COG1472	Belongs to the glycosyl hydrolase 3 family
XcfCFBP6988P_18390	COG0531	amino acid
XcfCFBP6988P_18400	COG1486	melibiose metabolic process
XcfCFBP6988P_18410	COG3537	Alpha-1,2-mannosidase
XcfCFBP6988P_18455	COG3142	Participates in the control of copper homeostasis
XcfCFBP6988P_18460	COG1446	asparaginase
XcfCFBP6988P_18485	COG0643	Histidine kinase
XcfCFBP6988P_18485	COG0784	Response regulator, receiver
XcfCFBP6988P_18485	COG2198	Histidine kinase
XcfCFBP6988P_18490	COG0840	transmembrane signaling receptor activity
XcfCFBP6988P_18495	COG0835	chemotaxis
XcfCFBP6988P_18510	COG0189	ligase activity
XcfCFBP6988P_18520	COG1397	ADP-ribosylglycohydrolase
XcfCFBP6988P_18530	COG1199	ATP-dependent helicase activity
XcfCFBP6988P_18540	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XcfCFBP6988P_18545	COG1216	Glycosyl transferase, family 2
XcfCFBP6988P_18545	COG1442	glycosyl transferase family 8
XcfCFBP6988P_18565	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XcfCFBP6988P_18575	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
XcfCFBP6988P_18580	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
XcfCFBP6988P_18585	COG0535	radical SAM domain protein
XcfCFBP6988P_18590	COG0535	radical SAM domain protein
XcfCFBP6988P_18605	COG0837	glucose binding
XcfCFBP6988P_18620	COG1643	Atp-dependent helicase
XcfCFBP6988P_18625	COG0783	Belongs to the Dps family
XcfCFBP6988P_18630	COG0514	ATP-dependent DNA helicase (RecQ)
XcfCFBP6988P_18670	COG0840	transmembrane signaling receptor activity
XcfCFBP6988P_18690	COG3920	Histidine kinase
XcfCFBP6988P_18695	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
XcfCFBP6988P_18705	COG0602	queuosine metabolic process
XcfCFBP6988P_18715	COG2885	chlorophyll binding
XcfCFBP6988P_18720	COG0823	Involved in the tonB-independent uptake of proteins
XcfCFBP6988P_18730	COG0848	biopolymer transport protein
XcfCFBP6988P_18740	COG0824	Thioesterase
XcfCFBP6988P_18745	COG2255	four-way junction helicase activity
XcfCFBP6988P_18755	COG3158	transport of potassium into the cell
XcfCFBP6988P_18760	COG0632	four-way junction helicase activity
XcfCFBP6988P_18765	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
XcfCFBP6988P_18770	COG0217	transcriptional regulatory protein
XcfCFBP6988P_18785	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
XcfCFBP6988P_18800	COG0477	Major facilitator Superfamily
XcfCFBP6988P_18840	COG0488	(ABC) transporter
XcfCFBP6988P_18880	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XcfCFBP6988P_18880	COG4651	solute:proton antiporter activity
XcfCFBP6988P_18890	COG4772	TonB-dependent receptor
XcfCFBP6988P_18900	COG4264	IucA IucC family
XcfCFBP6988P_18915	COG0019	diaminopimelate decarboxylase activity
XcfCFBP6988P_18940	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
XcfCFBP6988P_18950	COG1492	cobalamin metabolic process
XcfCFBP6988P_18960	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XcfCFBP6988P_18985	COG4206	TonB-dependent receptor
XcfCFBP6988P_18990	COG0542	response to heat
XcfCFBP6988P_18995	COG1116	anion transmembrane transporter activity
XcfCFBP6988P_19000	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XcfCFBP6988P_19005	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XcfCFBP6988P_19010	COG0667	Aldo Keto reductase
XcfCFBP6988P_19015	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XcfCFBP6988P_19020	COG4771	TonB-dependent receptor
XcfCFBP6988P_19025	COG2827	Endonuclease containing a URI domain
XcfCFBP6988P_19065	COG1877	trehalose-phosphatase activity
XcfCFBP6988P_19070	COG3387	PFAM Glycoside hydrolase 15-related
XcfCFBP6988P_19090	COG0840	transmembrane signaling receptor activity
XcfCFBP6988P_19095	COG3011	Protein conserved in bacteria
XcfCFBP6988P_19110	COG0564	pseudouridine synthase activity
XcfCFBP6988P_19115	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XcfCFBP6988P_19125	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
XcfCFBP6988P_19125	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XcfCFBP6988P_19140	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
XcfCFBP6988P_19145	COG0045	succinate-CoA ligase (ADP-forming) activity
XcfCFBP6988P_19165	COG4969	Belongs to the N-Me-Phe pilin family
XcfCFBP6988P_19180	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
XcfCFBP6988P_19185	COG0237	dephospho-CoA kinase activity
XcfCFBP6988P_19215	COG0745	RESPONSE REGULATOR receiver
XcfCFBP6988P_19225	COG0189	ligase activity
XcfCFBP6988P_19270	COG2022	thiamine diphosphate biosynthetic process
XcfCFBP6988P_19275	COG0220	tRNA (guanine-N7-)-methyltransferase activity
XcfCFBP6988P_19280	COG0471	metal ion transport
XcfCFBP6988P_19280	COG3273	potassium ion transport
XcfCFBP6988P_19305	COG1970	mechanosensitive ion channel activity
XcfCFBP6988P_19315	COG1609	Transcriptional regulator
XcfCFBP6988P_19325	COG3250	beta-galactosidase activity
XcfCFBP6988P_19330	COG4948	Mandelate Racemase Muconate Lactonizing
XcfCFBP6988P_19340	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XcfCFBP6988P_19350	COG0308	aminopeptidase N
XcfCFBP6988P_19355	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcfCFBP6988P_19365	COG0529	Catalyzes the synthesis of activated sulfate
XcfCFBP6988P_19365	COG2895	sulfate adenylyltransferase (ATP) activity
XcfCFBP6988P_19370	COG0175	sulfate reduction
XcfCFBP6988P_19375	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XcfCFBP6988P_19380	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XcfCFBP6988P_19385	COG0175	sulfate reduction
XcfCFBP6988P_19405	COG2205	protein histidine kinase activity
XcfCFBP6988P_19405	COG0784	Response regulator, receiver
XcfCFBP6988P_19405	COG2198	Histidine kinase
XcfCFBP6988P_19425	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XcfCFBP6988P_19425	COG1648	precorrin-2 dehydrogenase activity
XcfCFBP6988P_19440	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
XcfCFBP6988P_19445	COG3588	fructose-bisphosphate aldolase
XcfCFBP6988P_19460	COG0469	pyruvate kinase activity
XcfCFBP6988P_19470	COG0126	phosphoglycerate kinase activity
XcfCFBP6988P_19495	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
XcfCFBP6988P_19505	COG3047	cAMP biosynthetic process
XcfCFBP6988P_19510	COG3047	cAMP biosynthetic process
XcfCFBP6988P_19520	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XcfCFBP6988P_19520	COG3453	Protein conserved in bacteria
XcfCFBP6988P_19525	COG0725	ABC transporter, periplasmic molybdate-binding protein
XcfCFBP6988P_19530	COG4149	molybdate abc transporter
XcfCFBP6988P_19535	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
XcfCFBP6988P_19570	COG1376	ErfK ybiS ycfS ynhG family protein
XcfCFBP6988P_19575	COG0739	heme binding
XcfCFBP6988P_19580	COG4773	Receptor
XcfCFBP6988P_19585	COG0596	Alpha beta hydrolase
XcfCFBP6988P_19590	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
XcfCFBP6988P_19595	COG1301	dicarboxylic acid transport
XcfCFBP6988P_19610	COG2304	oxidoreductase activity
XcfCFBP6988P_19630	COG0714	Associated with various cellular activities
XcfCFBP6988P_19660	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XcfCFBP6988P_19685	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
XcfCFBP6988P_19695	COG2721	sulfolactate sulfo-lyase activity
XcfCFBP6988P_19710	COG2271	Major facilitator Superfamily
XcfCFBP6988P_19725	COG0583	DNA-binding transcription factor activity
XcfCFBP6988P_19730	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XcfCFBP6988P_19745	COG1561	YicC-like family, N-terminal region
XcfCFBP6988P_19750	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
XcfCFBP6988P_19760	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
XcfCFBP6988P_19765	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XcfCFBP6988P_19780	COG0006	proline dipeptidase activity
XcfCFBP6988P_19790	COG0006	proline dipeptidase activity
XcfCFBP6988P_19795	COG3079	Belongs to the UPF0149 family
XcfCFBP6988P_19815	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
XcfCFBP6988P_19825	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
XcfCFBP6988P_19835	COG2912	Transglutaminase-like superfamily
XcfCFBP6988P_19840	COG1773	rubredoxin
XcfCFBP6988P_19845	COG0352	thiamine-phosphate diphosphorylase activity
XcfCFBP6988P_19860	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XcfCFBP6988P_19880	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XcfCFBP6988P_19910	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XcfCFBP6988P_19915	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XcfCFBP6988P_19920	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6988P_19930	COG0671	phosphoesterase, PA-phosphatase related
XcfCFBP6988P_19945	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XcfCFBP6988P_19950	COG0563	adenylate kinase activity
XcfCFBP6988P_19965	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
XcfCFBP6988P_19975	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
XcfCFBP6988P_19995	COG3710	Transcriptional regulator
XcfCFBP6988P_20000	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
XcfCFBP6988P_20015	COG0840	transmembrane signaling receptor activity
XcfCFBP6988P_20020	COG0405	Gamma-glutamyltransferase
XcfCFBP6988P_20025	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
XcfCFBP6988P_20045	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
XcfCFBP6988P_20050	COG0473	3-isopropylmalate dehydrogenase activity
XcfCFBP6988P_20055	COG0066	3-isopropylmalate dehydratase activity
XcfCFBP6988P_20060	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
XcfCFBP6988P_20080	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XcfCFBP6988P_20085	COG1538	Outer membrane efflux protein
XcfCFBP6988P_20090	COG1519	Transferase
XcfCFBP6988P_20100	COG1560	Kdo2-lipid A biosynthetic process
XcfCFBP6988P_20150	COG0280	phosphate acetyltransferase
XcfCFBP6988P_20150	COG0281	malic enzyme
XcfCFBP6988P_20155	COG1301	dicarboxylic acid transport
XcfCFBP6988P_20180	COG0583	DNA-binding transcription factor activity
XcfCFBP6988P_20190	COG0667	Aldo Keto reductase
XcfCFBP6988P_20205	COG2197	response regulator
XcfCFBP6988P_20220	COG0642	Histidine kinase
XcfCFBP6988P_20240	COG2851	Citrate transporter
XcfCFBP6988P_20245	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6988P_20250	COG1609	Transcriptional regulator
XcfCFBP6988P_20255	COG2211	Major facilitator Superfamily
XcfCFBP6988P_20285	COG1162	GTPase activity
XcfCFBP6988P_20320	COG0436	Aminotransferase
XcfCFBP6988P_20335	COG0726	polysaccharide deacetylase
XcfCFBP6988P_20340	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XcfCFBP6988P_20355	COG3964	amidohydrolase
XcfCFBP6988P_20360	COG0402	S-adenosylhomocysteine deaminase activity
XcfCFBP6988P_20385	COG1307	EDD domain protein, DegV family
XcfCFBP6988P_20390	COG0242	peptide deformylase activity
XcfCFBP6988P_20415	COG0457	Tetratricopeptide repeat
XcfCFBP6988P_20420	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
XcfCFBP6988P_20425	COG1215	transferase activity, transferring glycosyl groups
XcfCFBP6988P_20430	COG1215	transferase activity, transferring glycosyl groups
XcfCFBP6988P_20445	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
XcfCFBP6988P_20500	COG2188	Transcriptional regulator
XcfCFBP6988P_20510	COG1450	Type ii and iii secretion system protein
XcfCFBP6988P_20525	COG3166	PFAM Fimbrial assembly family protein
XcfCFBP6988P_20530	COG3156	type II secretion system protein K
XcfCFBP6988P_20535	COG4795	General secretion pathway protein
XcfCFBP6988P_20540	COG2165	general secretion pathway protein
XcfCFBP6988P_20545	COG4970	Tfp pilus assembly protein FimT
XcfCFBP6988P_20550	COG2165	general secretion pathway protein
XcfCFBP6988P_20555	COG1459	type II secretion system
XcfCFBP6988P_20565	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XcfCFBP6988P_20570	COG1404	Belongs to the peptidase S8 family
XcfCFBP6988P_20575	COG5295	Hep Hag repeat protein
XcfCFBP6988P_20580	COG1404	Belongs to the peptidase S8 family
XcfCFBP6988P_20585	COG5295	Hep Hag repeat protein
XcfCFBP6988P_20590	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XcfCFBP6988P_20590	COG0047	phosphoribosylformylglycinamidine synthase activity
XcfCFBP6988P_20605	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XcfCFBP6988P_20620	COG4974	Belongs to the 'phage' integrase family
XcfCFBP6988P_20635	COG0795	lipopolysaccharide-transporting ATPase activity
XcfCFBP6988P_20645	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XcfCFBP6988P_20660	COG0525	valine-tRNA ligase activity
XcfCFBP6988P_20695	COG1183	phosphatidylcholine synthase activity
XcfCFBP6988P_20705	COG0442	prolyl-tRNA aminoacylation
XcfCFBP6988P_20720	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XcfCFBP6988P_20725	COG1127	ABC transporter
XcfCFBP6988P_20730	COG3218	ABC-type transport auxiliary lipoprotein component
XcfCFBP6988P_20730	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XcfCFBP6988P_20765	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XcfCFBP6988P_20770	COG0662	Cupin 2, conserved barrel domain protein
XcfCFBP6988P_20770	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
XcfCFBP6988P_20800	COG2086	electron transfer activity
XcfCFBP6988P_20815	COG0546	phosphoglycolate phosphatase activity
XcfCFBP6988P_20815	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
XcfCFBP6988P_20820	COG0277	FAD linked oxidase domain protein
XcfCFBP6988P_20835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XcfCFBP6988P_20865	COG0438	transferase activity, transferring glycosyl groups
XcfCFBP6988P_20865	COG1216	Glycosyl transferase, family 2
XcfCFBP6988P_20885	COG0626	cystathionine gamma-synthase activity
XcfCFBP6988P_20915	COG0625	glutathione transferase activity
XcfCFBP6988P_20930	COG0513	Belongs to the DEAD box helicase family
XcfCFBP6988P_20940	COG4771	TonB-dependent receptor
XcfCFBP6988P_20945	COG0720	synthase
XcfCFBP6988P_20970	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
XcfCFBP6988P_20975	COG1956	GAF domain-containing protein
XcfCFBP6988P_20985	COG2819	hydrolase of the alpha beta superfamily
XcfCFBP6988P_20995	COG0546	phosphoglycolate phosphatase activity
XcfCFBP6988P_21000	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
XcfCFBP6988P_21005	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XcfCFBP6988P_21020	COG0339	signal peptide processing
XcfCFBP6988P_21070	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XcfCFBP6988P_21075	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcfCFBP6988P_21080	COG1136	(ABC) transporter
XcfCFBP6988P_21085	COG0577	efflux transmembrane transporter activity
XcfCFBP6988P_21090	COG1136	(ABC) transporter
XcfCFBP6988P_21090	COG0577	efflux transmembrane transporter activity
XcfCFBP6988P_21105	COG4191	Histidine kinase
XcfCFBP6988P_21110	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
XcfCFBP6988P_21130	COG0355	proton-transporting ATP synthase activity, rotational mechanism
XcfCFBP6988P_21135	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
XcfCFBP6988P_21140	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
XcfCFBP6988P_21145	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
XcfCFBP6988P_21150	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
XcfCFBP6988P_21155	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
XcfCFBP6988P_21165	COG0356	it plays a direct role in the translocation of protons across the membrane
XcfCFBP6988P_21185	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XcfCFBP6988P_21195	COG0508	dehydrogenase complex catalyzes the overall conversion of
XcfCFBP6988P_21235	COG2011	ABC-type metal ion transport system permease component
XcfCFBP6988P_21240	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
XcfCFBP6988P_21245	COG0697	spore germination
XcfCFBP6988P_21250	COG1666	GTP binding
XcfCFBP6988P_21260	COG5002	protein histidine kinase activity
XcfCFBP6988P_21260	COG2198	Histidine kinase
XcfCFBP6988P_21260	COG0784	Response regulator, receiver
XcfCFBP6988P_21285	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XcfCFBP6988P_21290	COG1187	pseudouridine synthase activity
XcfCFBP6988P_21295	COG2813	Specifically methylates the guanine in position
XcfCFBP6988P_21315	COG2205	protein histidine kinase activity
XcfCFBP6988P_21315	COG2202	Pas domain
XcfCFBP6988P_21335	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
XcfCFBP6988P_21340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XcfCFBP6988P_21395	COG0842	Transport permease protein
XcfCFBP6988P_21405	COG0025	NhaP-type Na H and K H
XcfCFBP6988P_21415	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
XcfCFBP6988P_21420	COG1573	uracil-dna glycosylase
XcfCFBP6988P_21430	COG3384	dioxygenase
XcfCFBP6988P_21440	COG0583	DNA-binding transcription factor activity
XcfCFBP6988P_21450	COG0667	Aldo Keto reductase
XcfCFBP6988P_21465	COG3590	peptidase
XcfCFBP6988P_21480	COG0531	amino acid
XcfCFBP6988P_21495	COG2972	Histidine kinase
XcfCFBP6988P_21515	COG3685	Protein conserved in bacteria
XcfCFBP6988P_21520	COG3546	catalase activity
XcfCFBP6988P_21555	COG2204	response regulator
XcfCFBP6988P_21570	COG1271	oxidase subunit
XcfCFBP6988P_21575	COG1294	oxidase, subunit
XcfCFBP6988P_21590	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6988P_21595	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
XcfCFBP6988P_21615	COG1132	(ABC) transporter
XcfCFBP6988P_21630	COG1063	alcohol dehydrogenase
XcfCFBP6988P_21705	COG0251	oxidation-reduction process
XcfCFBP6988P_21720	COG0840	transmembrane signaling receptor activity
XcfCFBP6988P_21735	COG0583	DNA-binding transcription factor activity
XcfCFBP6988P_21740	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XcfCFBP6988P_21770	COG0659	secondary active sulfate transmembrane transporter activity
XcfCFBP6988P_21785	COG0024	Methionine aminopeptidase
XcfCFBP6988P_21805	COG1487	ribonuclease activity
XcfCFBP6988P_21880	COG4974	Belongs to the 'phage' integrase family
XcfCFBP6988P_21945	COG1196	nuclear chromosome segregation
XcfCFBP6988P_21975	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XcfCFBP6988P_21980	COG1490	D-aminoacyl-tRNA deacylase activity
XcfCFBP6988P_21985	COG1560	Kdo2-lipid A biosynthetic process
XcfCFBP6988P_22040	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XcfCFBP6988P_22040	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
XcfCFBP6988P_22045	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
XcfCFBP6988P_22050	COG0242	peptide deformylase activity
XcfCFBP6988P_22055	COG1652	LysM domain
XcfCFBP6988P_22060	COG0758	DNA mediated transformation
XcfCFBP6988P_22080	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XcfCFBP6988P_22080	COG1754	DNA topoisomerase type I activity
XcfCFBP6988P_22085	COG0009	L-threonylcarbamoyladenylate synthase
XcfCFBP6988P_22100	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6988P_22115	COG0616	signal peptide processing
XcfCFBP6988P_22120	COG0534	Mate efflux family protein
XcfCFBP6988P_22140	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
XcfCFBP6988P_22145	COG0625	glutathione transferase activity
XcfCFBP6988P_22160	COG1252	NADH dehydrogenase
XcfCFBP6988P_22165	COG2860	membrane
XcfCFBP6988P_22170	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XcfCFBP6988P_22175	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
XcfCFBP6988P_22180	COG2201	protein-glutamate methylesterase activity
XcfCFBP6988P_22185	COG2177	Part of the ABC transporter FtsEX involved in
XcfCFBP6988P_22190	COG2884	Cell division ATP-binding protein ftsE
XcfCFBP6988P_22195	COG0513	Belongs to the DEAD box helicase family
XcfCFBP6988P_22200	COG3118	belongs to the thioredoxin family
XcfCFBP6988P_22205	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
XcfCFBP6988P_22210	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
XcfCFBP6988P_22215	COG0583	DNA-binding transcription factor activity
XcfCFBP6988P_22235	COG1652	LysM domain
XcfCFBP6988P_22240	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XcfCFBP6988P_22240	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XcfCFBP6988P_22245	COG1473	amidohydrolase
XcfCFBP6988P_22250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcfCFBP6988P_22255	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcfCFBP6988P_22275	COG5383	Protein conserved in bacteria
XcfCFBP6988P_22335	COG4948	Mandelate Racemase Muconate Lactonizing
XcfCFBP6988P_22345	COG0531	amino acid
XcfCFBP6988P_22360	COG4682	membrane
XcfCFBP6988P_22365	COG2133	pyrroloquinoline quinone binding
XcfCFBP6988P_22375	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
XcfCFBP6988P_22380	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
XcfCFBP6988P_22390	COG1610	YqeY-like protein
XcfCFBP6988P_22400	COG1295	ribonuclease BN
XcfCFBP6988P_22405	COG0358	DNA primase activity
XcfCFBP6988P_22420	COG0109	protoheme IX farnesyltransferase activity
XcfCFBP6988P_22450	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
XcfCFBP6988P_22460	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XcfCFBP6988P_22505	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
XcfCFBP6988P_22510	COG0739	heme binding
XcfCFBP6988P_22515	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
XcfCFBP6988P_22525	COG2223	nitrite transmembrane transporter activity
XcfCFBP6988P_22530	COG0708	Exodeoxyribonuclease III
XcfCFBP6988P_22535	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
XcfCFBP6988P_22545	COG1192	Involved in chromosome partitioning
XcfCFBP6988P_22550	COG1475	DNA binding
XcfCFBP6988P_22570	COG0463	Glycosyl transferase, family 2
XcfCFBP6988P_22590	COG0756	dUTP diphosphatase activity
XcfCFBP6988P_22595	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
XcfCFBP6988P_22600	COG2003	Belongs to the UPF0758 family
XcfCFBP6988P_22605	COG0018	arginyl-trna synthetase
XcfCFBP6988P_22620	COG4221	oxidoreductase activity
XcfCFBP6988P_22625	COG2755	lipolytic protein G-D-S-L family
XcfCFBP6988P_22625	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
XcfCFBP6988P_22635	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XcfCFBP6988P_22640	COG1166	arginine decarboxylase activity
XcfCFBP6988P_22645	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
XcfCFBP6988P_22670	COG3525	Glycosyl hydrolase, family 20, catalytic domain
XcfCFBP6988P_22670	COG3291	Pkd domain containing protein
XcfCFBP6988P_22690	COG0606	chelatase, subunit chli
XcfCFBP6988P_22700	COG4943	cyclic-guanylate-specific phosphodiesterase activity
XcfCFBP6988P_22740	COG1690	Belongs to the RtcB family
XcfCFBP6988P_22775	COG1090	epimerase
XcfCFBP6988P_22785	COG0642	Histidine kinase
XcfCFBP6988P_22810	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XcfCFBP6988P_22840	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XcfCFBP6988P_22850	COG3328	transposase activity
XcfCFBP6988P_22860	COG0753	catalase activity
XcfCFBP6988P_22875	COG2197	response regulator
XcfCFBP6988P_22880	COG4585	Histidine kinase
XcfCFBP6988P_22885	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcfCFBP6988P_22890	COG1136	(ABC) transporter
XcfCFBP6988P_23005	COG3451	type IV secretory pathway VirB4
XcfCFBP6988P_23020	COG4962	Type ii secretion system protein e
XcfCFBP6988P_23045	COG3328	transposase activity
XcfCFBP6988P_23240	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XcfCFBP6988P_23245	COG4691	Plasmid stability protein
XcfCFBP6988P_23250	COG1487	ribonuclease activity
XcfCFBP6988P_23315	COG3846	protein secretion by the type IV secretion system
