locus-tag	class	description
XcfCFBP6992P_00075	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
XcfCFBP6992P_00095	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
XcfCFBP6992P_00145	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XcfCFBP6992P_00175	COG1199	ATP-dependent helicase activity
XcfCFBP6992P_00190	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
XcfCFBP6992P_00265	COG0625	glutathione transferase activity
XcfCFBP6992P_00300	COG4555	ABC transporter
XcfCFBP6992P_00310	COG1476	TRANSCRIPTIONal
XcfCFBP6992P_00330	COG1230	cation diffusion facilitator family transporter
XcfCFBP6992P_00355	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XcfCFBP6992P_00360	COG1131	(ABC) transporter
XcfCFBP6992P_00365	COG0842	Transport permease protein
XcfCFBP6992P_00370	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XcfCFBP6992P_00400	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XcfCFBP6992P_00410	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XcfCFBP6992P_00425	COG0045	succinate-CoA ligase (ADP-forming) activity
XcfCFBP6992P_00425	COG1042	CoA-binding domain protein
XcfCFBP6992P_00425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XcfCFBP6992P_00430	COG2239	Acts as a magnesium transporter
XcfCFBP6992P_00450	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XcfCFBP6992P_00455	COG3387	PFAM Glycoside hydrolase 15-related
XcfCFBP6992P_00470	COG3100	YcgL domain-containing protein
XcfCFBP6992P_00475	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XcfCFBP6992P_00485	COG0463	Glycosyl transferase, family 2
XcfCFBP6992P_00505	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6992P_00545	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XcfCFBP6992P_00560	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XcfCFBP6992P_00590	COG0823	Involved in the tonB-independent uptake of proteins
XcfCFBP6992P_00590	COG1506	peptidase
XcfCFBP6992P_00590	COG4946	Tricorn protease homolog
XcfCFBP6992P_00610	COG0408	coproporphyrinogen oxidase activity
XcfCFBP6992P_00650	COG0515	serine threonine protein kinase
XcfCFBP6992P_00655	COG0631	protein serine/threonine phosphatase activity
XcfCFBP6992P_00780	COG3328	transposase activity
XcfCFBP6992P_00845	COG0210	DNA helicase
XcfCFBP6992P_00855	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XcfCFBP6992P_00860	COG0583	DNA-binding transcription factor activity
XcfCFBP6992P_00865	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XcfCFBP6992P_00880	COG2159	amidohydrolase
XcfCFBP6992P_00910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcfCFBP6992P_00930	COG0357	Ribosomal RNA small subunit methyltransferase G
XcfCFBP6992P_00935	COG3540	Alkaline phosphatase
XcfCFBP6992P_00945	COG2091	lysine biosynthetic process via aminoadipic acid
XcfCFBP6992P_00960	COG0708	Exodeoxyribonuclease III
XcfCFBP6992P_00965	COG1940	carbohydrate kinase activity
XcfCFBP6992P_00965	COG1846	Transcriptional regulator
XcfCFBP6992P_00975	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XcfCFBP6992P_00990	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XcfCFBP6992P_00995	COG3162	membrane
XcfCFBP6992P_01005	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XcfCFBP6992P_01035	COG3507	Belongs to the glycosyl hydrolase 43 family
XcfCFBP6992P_01055	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6992P_01060	COG0179	Fumarylacetoacetate (FAA) hydrolase
XcfCFBP6992P_01065	COG4948	Mandelate Racemase Muconate Lactonizing
XcfCFBP6992P_01070	COG3254	rhamnose metabolic process
XcfCFBP6992P_01075	COG0738	Major facilitator superfamily
XcfCFBP6992P_01080	COG1414	Transcriptional regulator
XcfCFBP6992P_01085	COG1971	Probably functions as a manganese efflux pump
XcfCFBP6992P_01090	COG2205	protein histidine kinase activity
XcfCFBP6992P_01105	COG3459	Glycosyltransferase 36 associated
XcfCFBP6992P_01110	COG2211	Major facilitator Superfamily
XcfCFBP6992P_01115	COG3265	gluconokinase activity
XcfCFBP6992P_01125	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XcfCFBP6992P_01150	COG2911	Protein conserved in bacteria
XcfCFBP6992P_01155	COG0729	surface antigen
XcfCFBP6992P_01185	COG0752	glycyl-tRNA synthetase alpha subunit
XcfCFBP6992P_01190	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XcfCFBP6992P_01205	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XcfCFBP6992P_01205	COG0519	Catalyzes the synthesis of GMP from XMP
XcfCFBP6992P_01215	COG0805	protein transport
XcfCFBP6992P_01220	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XcfCFBP6992P_01225	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XcfCFBP6992P_01235	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
XcfCFBP6992P_01255	COG2974	May be involved in recombination
XcfCFBP6992P_01260	COG0037	tRNA processing
XcfCFBP6992P_01265	COG2115	Belongs to the xylose isomerase family
XcfCFBP6992P_01275	COG3661	Belongs to the glycosyl hydrolase 67 family
XcfCFBP6992P_01285	COG4948	Mandelate Racemase Muconate Lactonizing
XcfCFBP6992P_01295	COG1472	Belongs to the glycosyl hydrolase 3 family
XcfCFBP6992P_01300	COG0246	Mannitol dehydrogenase
XcfCFBP6992P_01350	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XcfCFBP6992P_01380	COG3386	PFAM SMP-30 Gluconolaconase
XcfCFBP6992P_01390	COG3250	beta-galactosidase activity
XcfCFBP6992P_01395	COG1904	glucuronate isomerase
XcfCFBP6992P_01400	COG3693	PFAM glycoside hydrolase, family 10
XcfCFBP6992P_01410	COG3693	PFAM glycoside hydrolase, family 10
XcfCFBP6992P_01425	COG2211	Major facilitator Superfamily
XcfCFBP6992P_01460	COG0604	alcohol dehydrogenase
XcfCFBP6992P_01460	COG3321	synthase
XcfCFBP6992P_01460	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6992P_01465	COG2937	Belongs to the GPAT DAPAT family
XcfCFBP6992P_01500	COG0284	orotidine-5'-phosphate decarboxylase activity
XcfCFBP6992P_01505	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
XcfCFBP6992P_01515	COG3132	Protein of unknown function, DUF480
XcfCFBP6992P_01530	COG0210	DNA helicase
XcfCFBP6992P_01535	COG1435	thymidine kinase activity
XcfCFBP6992P_01545	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
XcfCFBP6992P_01555	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
XcfCFBP6992P_01585	COG3135	benzoate transporter
XcfCFBP6992P_01610	COG0676	glucose-6-phosphate 1-epimerase activity
XcfCFBP6992P_01620	COG3012	SEC-C Motif Domain Protein
XcfCFBP6992P_01625	COG0730	response to heat
XcfCFBP6992P_01650	COG0302	gtp cyclohydrolase
XcfCFBP6992P_01665	COG1566	PFAM secretion protein HlyD family protein
XcfCFBP6992P_01675	COG1289	transmembrane transporter activity
XcfCFBP6992P_01680	COG0477	Major facilitator Superfamily
XcfCFBP6992P_01690	COG0583	DNA-binding transcription factor activity
XcfCFBP6992P_01705	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XcfCFBP6992P_01780	COG0564	pseudouridine synthase activity
XcfCFBP6992P_01820	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6992P_01865	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
XcfCFBP6992P_01870	COG1074	ATP-dependent DNA helicase activity
XcfCFBP6992P_01875	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
XcfCFBP6992P_01910	COG1127	ABC transporter
XcfCFBP6992P_01915	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XcfCFBP6992P_01920	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XcfCFBP6992P_01935	COG2853	Lipoprotein
XcfCFBP6992P_01945	COG0386	Belongs to the glutathione peroxidase family
XcfCFBP6992P_01965	COG0625	glutathione transferase activity
XcfCFBP6992P_01975	COG0531	amino acid
XcfCFBP6992P_01980	COG3537	Alpha-1,2-mannosidase
XcfCFBP6992P_01995	COG3706	GGDEF domain
XcfCFBP6992P_02000	COG3835	regulator
XcfCFBP6992P_02005	COG1929	Belongs to the glycerate kinase type-1 family
XcfCFBP6992P_02010	COG2271	Major facilitator Superfamily
XcfCFBP6992P_02025	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XcfCFBP6992P_02030	COG0861	Integral membrane protein TerC family
XcfCFBP6992P_02040	COG0584	glycerophosphoryl diester phosphodiesterase
XcfCFBP6992P_02055	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
XcfCFBP6992P_02070	COG0706	membrane insertase activity
XcfCFBP6992P_02075	COG0594	ribonuclease P activity
XcfCFBP6992P_02090	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
XcfCFBP6992P_02100	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
XcfCFBP6992P_02105	COG0187	DNA topoisomerase II activity
XcfCFBP6992P_02115	COG0501	Belongs to the peptidase M48B family
XcfCFBP6992P_02150	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
XcfCFBP6992P_02160	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XcfCFBP6992P_02210	COG0793	Belongs to the peptidase S41A family
XcfCFBP6992P_02215	COG4942	peptidase
XcfCFBP6992P_02225	COG2234	aminopeptidase activity
XcfCFBP6992P_02235	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XcfCFBP6992P_02240	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XcfCFBP6992P_02245	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XcfCFBP6992P_02255	COG1064	alcohol dehydrogenase
XcfCFBP6992P_02270	COG0493	'glutamate synthase
XcfCFBP6992P_02275	COG0069	glutamate synthase activity
XcfCFBP6992P_02275	COG0070	glutamate synthase
XcfCFBP6992P_02275	COG0067	glutamate synthase
XcfCFBP6992P_02365	COG1111	helicase
XcfCFBP6992P_02365	COG1205	dead DEAH box helicase
XcfCFBP6992P_02370	COG1272	protein, Hemolysin III
XcfCFBP6992P_02390	COG0300	oxidoreductase activity
XcfCFBP6992P_02410	COG2249	NAD(P)H dehydrogenase (quinone) activity
XcfCFBP6992P_02415	COG3328	transposase activity
XcfCFBP6992P_02450	COG3237	CsbD-like
XcfCFBP6992P_02500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XcfCFBP6992P_02510	COG0477	Major facilitator Superfamily
XcfCFBP6992P_02560	COG0714	Associated with various cellular activities
XcfCFBP6992P_02595	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
XcfCFBP6992P_02605	COG4772	TonB-dependent receptor
XcfCFBP6992P_02620	COG1012	belongs to the aldehyde dehydrogenase family
XcfCFBP6992P_02645	COG1304	FMN binding
XcfCFBP6992P_02660	COG4585	Histidine kinase
XcfCFBP6992P_02665	COG2197	response regulator
XcfCFBP6992P_02685	COG3710	Transcriptional regulator
XcfCFBP6992P_02690	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
XcfCFBP6992P_02790	COG0366	Alpha amylase catalytic
XcfCFBP6992P_02795	COG0366	Alpha amylase catalytic
XcfCFBP6992P_02800	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XcfCFBP6992P_02820	COG2755	lipolytic protein G-D-S-L family
XcfCFBP6992P_02820	COG0657	acetylesterase activity
XcfCFBP6992P_02830	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XcfCFBP6992P_02845	COG3507	Belongs to the glycosyl hydrolase 43 family
XcfCFBP6992P_02850	COG1609	Transcriptional regulator
XcfCFBP6992P_02865	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
XcfCFBP6992P_02870	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6992P_02880	COG2755	lipolytic protein G-D-S-L family
XcfCFBP6992P_02890	COG3186	Phenylalanine-4-hydroxylase
XcfCFBP6992P_02895	COG1522	sequence-specific DNA binding
XcfCFBP6992P_02905	COG1752	Esterase of the alpha-beta hydrolase superfamily
XcfCFBP6992P_02915	COG1119	ATPase activity
XcfCFBP6992P_02930	COG1125	glycine betaine transport
XcfCFBP6992P_02945	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XcfCFBP6992P_02975	COG0489	protein tyrosine kinase activity
XcfCFBP6992P_02980	COG2062	phosphohistidine phosphatase, SixA
XcfCFBP6992P_02990	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XcfCFBP6992P_03035	COG1968	undecaprenyl-diphosphatase activity
XcfCFBP6992P_03045	COG0174	glutamine synthetase
XcfCFBP6992P_03050	COG0347	Belongs to the P(II) protein family
XcfCFBP6992P_03055	COG0004	ammonium transporteR
XcfCFBP6992P_03060	COG3852	Histidine kinase
XcfCFBP6992P_03065	COG2204	response regulator
XcfCFBP6992P_03070	COG2032	superoxide dismutase activity
XcfCFBP6992P_03075	COG2032	superoxide dismutase activity
XcfCFBP6992P_03080	COG0346	lactoylglutathione lyase activity
XcfCFBP6992P_03090	COG0183	Belongs to the thiolase family
XcfCFBP6992P_03125	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XcfCFBP6992P_03130	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
XcfCFBP6992P_03135	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
XcfCFBP6992P_03150	COG0028	Belongs to the TPP enzyme family
XcfCFBP6992P_03155	COG2205	protein histidine kinase activity
XcfCFBP6992P_03180	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
XcfCFBP6992P_03195	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XcfCFBP6992P_03205	COG0596	Alpha beta hydrolase
XcfCFBP6992P_03210	COG0727	PFAM Uncharacterised protein family (UPF0153)
XcfCFBP6992P_03215	COG0318	PFAM AMP-dependent synthetase and ligase
XcfCFBP6992P_03220	COG0745	RESPONSE REGULATOR receiver
XcfCFBP6992P_03230	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XcfCFBP6992P_03250	COG1181	Belongs to the D-alanine--D-alanine ligase family
XcfCFBP6992P_03265	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XcfCFBP6992P_03275	COG0564	pseudouridine synthase activity
XcfCFBP6992P_03295	COG1446	asparaginase
XcfCFBP6992P_03300	COG0339	signal peptide processing
XcfCFBP6992P_03335	COG0475	glutathione-regulated potassium exporter activity
XcfCFBP6992P_03340	COG0583	DNA-binding transcription factor activity
XcfCFBP6992P_03345	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
XcfCFBP6992P_03350	COG2224	Isocitrate lyase
XcfCFBP6992P_03380	COG4770	biotin carboxylase activity
XcfCFBP6992P_03385	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XcfCFBP6992P_03390	COG1960	acyl-CoA dehydrogenase activity
XcfCFBP6992P_03460	COG0697	spore germination
XcfCFBP6992P_03470	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
XcfCFBP6992P_03475	COG1846	Transcriptional regulator
XcfCFBP6992P_03480	COG1764	response to oxidative stress
XcfCFBP6992P_03510	COG2130	NADP-dependent
XcfCFBP6992P_03525	COG1187	pseudouridine synthase activity
XcfCFBP6992P_03540	COG1643	Atp-dependent helicase
XcfCFBP6992P_03545	COG4807	Protein conserved in bacteria
XcfCFBP6992P_03550	COG2351	hydroxyisourate hydrolase activity
XcfCFBP6992P_03555	COG2072	flavoprotein involved in K transport
XcfCFBP6992P_03575	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
XcfCFBP6992P_03585	COG0583	DNA-binding transcription factor activity
XcfCFBP6992P_03620	COG2252	PERMEase
XcfCFBP6992P_03645	COG0084	hydrolase, TatD family'
XcfCFBP6992P_03655	COG0583	DNA-binding transcription factor activity
XcfCFBP6992P_03660	COG2814	Major facilitator Superfamily
XcfCFBP6992P_03670	COG2267	carboxylic ester hydrolase activity
XcfCFBP6992P_03675	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
XcfCFBP6992P_03680	COG1902	pentaerythritol trinitrate reductase activity
XcfCFBP6992P_03700	COG0745	RESPONSE REGULATOR receiver
XcfCFBP6992P_03705	COG2205	protein histidine kinase activity
XcfCFBP6992P_03710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcfCFBP6992P_03735	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XcfCFBP6992P_03740	COG0583	DNA-binding transcription factor activity
XcfCFBP6992P_03775	COG0702	epimerase
XcfCFBP6992P_03780	COG1733	regulation of RNA biosynthetic process
XcfCFBP6992P_03810	COG0129	dihydroxy-acid dehydratase activity
XcfCFBP6992P_03825	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
XcfCFBP6992P_03880	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
XcfCFBP6992P_03885	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
XcfCFBP6992P_03910	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
XcfCFBP6992P_03915	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
XcfCFBP6992P_03925	COG3485	protocatechuate 3,4-dioxygenase
XcfCFBP6992P_03930	COG3485	protocatechuate 3,4-dioxygenase
XcfCFBP6992P_03940	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XcfCFBP6992P_03945	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XcfCFBP6992P_03955	COG1414	Transcriptional regulator
XcfCFBP6992P_03965	COG0657	acetylesterase activity
XcfCFBP6992P_03975	COG0445	tRNA wobble uridine modification
XcfCFBP6992P_03985	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
XcfCFBP6992P_04010	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6992P_04015	COG2267	carboxylic ester hydrolase activity
XcfCFBP6992P_04025	COG0156	8-amino-7-oxononanoate synthase activity
XcfCFBP6992P_04030	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
XcfCFBP6992P_04035	COG1040	competence protein
XcfCFBP6992P_04045	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
XcfCFBP6992P_04125	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XcfCFBP6992P_04205	COG1368	sulfuric ester hydrolase activity
XcfCFBP6992P_04215	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XcfCFBP6992P_04220	COG2354	Protein conserved in bacteria
XcfCFBP6992P_04230	COG0297	glycogen (starch) synthase activity
XcfCFBP6992P_04235	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XcfCFBP6992P_04240	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XcfCFBP6992P_04265	COG0702	epimerase
XcfCFBP6992P_04270	COG1858	cytochrome C peroxidase
XcfCFBP6992P_04285	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6992P_04320	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcfCFBP6992P_04325	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6992P_04335	COG0513	Belongs to the DEAD box helicase family
XcfCFBP6992P_04340	COG0508	dehydrogenase complex catalyzes the overall conversion of
XcfCFBP6992P_04355	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
XcfCFBP6992P_04370	COG3483	tryptophan 2,3-dioxygenase activity
XcfCFBP6992P_04375	COG3104	oligopeptide transport
XcfCFBP6992P_04395	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
XcfCFBP6992P_04415	COG1320	monovalent cation:proton antiporter activity
XcfCFBP6992P_04420	COG2212	antiporter activity
XcfCFBP6992P_04430	COG0651	ATP synthesis coupled electron transport
XcfCFBP6992P_04435	COG1006	Multisubunit Na H antiporter MnhC subunit
XcfCFBP6992P_04440	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XcfCFBP6992P_04440	COG2111	Na H antiporter
XcfCFBP6992P_04465	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
XcfCFBP6992P_04470	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
XcfCFBP6992P_04485	COG0456	acetyltransferase
XcfCFBP6992P_04490	COG1597	lipid kinase activity
XcfCFBP6992P_04515	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
XcfCFBP6992P_04520	COG0134	indole-3-glycerol-phosphate synthase activity
XcfCFBP6992P_04530	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XcfCFBP6992P_04535	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
XcfCFBP6992P_04545	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
XcfCFBP6992P_04555	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
XcfCFBP6992P_04570	COG1051	belongs to the nudix hydrolase family
XcfCFBP6992P_04610	COG0316	Belongs to the HesB IscA family
XcfCFBP6992P_04630	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XcfCFBP6992P_04650	COG2814	Major facilitator Superfamily
XcfCFBP6992P_04660	COG2814	Major facilitator Superfamily
XcfCFBP6992P_04665	COG1289	transmembrane transporter activity
XcfCFBP6992P_04670	COG0151	Belongs to the GarS family
XcfCFBP6992P_04680	COG0138	bifunctional purine biosynthesis protein purh
XcfCFBP6992P_04685	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XcfCFBP6992P_04690	COG2267	carboxylic ester hydrolase activity
XcfCFBP6992P_04695	COG2453	phosphatase
XcfCFBP6992P_04695	COG0671	phosphoesterase, PA-phosphatase related
XcfCFBP6992P_04720	COG4589	Belongs to the CDS family
XcfCFBP6992P_04725	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
XcfCFBP6992P_04750	COG2264	protein methyltransferase activity
XcfCFBP6992P_04770	COG0439	Biotin carboxylase
XcfCFBP6992P_04780	COG0511	ligase activity, forming carbon-carbon bonds
XcfCFBP6992P_04785	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
XcfCFBP6992P_04795	COG1324	tolerance protein
XcfCFBP6992P_04805	COG2356	endonuclease I
XcfCFBP6992P_04815	COG0459	protein refolding
XcfCFBP6992P_04830	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XcfCFBP6992P_04845	COG3386	PFAM SMP-30 Gluconolaconase
XcfCFBP6992P_04855	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
XcfCFBP6992P_04860	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XcfCFBP6992P_04890	COG0778	Nitroreductase
XcfCFBP6992P_04895	COG2353	YceI-like domain
XcfCFBP6992P_04925	COG3052	prosthetic group binding
XcfCFBP6992P_04950	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XcfCFBP6992P_04960	COG1802	Transcriptional regulator
XcfCFBP6992P_05120	COG1082	Xylose isomerase domain protein TIM barrel
XcfCFBP6992P_05140	COG4221	oxidoreductase activity
XcfCFBP6992P_05155	COG4221	oxidoreductase activity
XcfCFBP6992P_05165	COG0435	Glutathione S-transferase
XcfCFBP6992P_05200	COG1506	peptidase
XcfCFBP6992P_05200	COG0823	Involved in the tonB-independent uptake of proteins
XcfCFBP6992P_05250	COG4305	rare lipoprotein A
XcfCFBP6992P_05255	COG5297	Belongs to the glycosyl hydrolase family 6
XcfCFBP6992P_05265	COG1113	amino acid transport
XcfCFBP6992P_05285	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
XcfCFBP6992P_05335	COG0840	transmembrane signaling receptor activity
XcfCFBP6992P_05340	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XcfCFBP6992P_05340	COG5297	Belongs to the glycosyl hydrolase family 6
XcfCFBP6992P_05345	COG0659	secondary active sulfate transmembrane transporter activity
XcfCFBP6992P_05370	COG2943	transferase activity, transferring hexosyl groups
XcfCFBP6992P_05380	COG3275	phosphorelay sensor kinase activity
XcfCFBP6992P_05390	COG0181	hydroxymethylbilane synthase activity
XcfCFBP6992P_05420	COG1505	serine-type exopeptidase activity
XcfCFBP6992P_05425	COG0436	Aminotransferase
XcfCFBP6992P_05435	COG2832	Protein of unknown function (DUF454)
XcfCFBP6992P_05445	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
XcfCFBP6992P_05455	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XcfCFBP6992P_05460	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
XcfCFBP6992P_05465	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
XcfCFBP6992P_05490	COG2226	methyltransferase
XcfCFBP6992P_05495	COG3300	MHYT domain
XcfCFBP6992P_05495	COG5001	Diguanylate cyclase
XcfCFBP6992P_05500	COG0308	aminopeptidase N
XcfCFBP6992P_05550	COG3284	Transcriptional regulator
XcfCFBP6992P_05555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XcfCFBP6992P_05560	COG1077	Cell shape determining protein MreB Mrl
XcfCFBP6992P_05565	COG1792	Involved in formation and maintenance of cell shape
XcfCFBP6992P_05580	COG0772	Belongs to the SEDS family
XcfCFBP6992P_05590	COG2951	lytic endotransglycosylase activity
XcfCFBP6992P_05595	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XcfCFBP6992P_05605	COG1686	Belongs to the peptidase S11 family
XcfCFBP6992P_05615	COG2921	Belongs to the UPF0250 family
XcfCFBP6992P_05620	COG0321	lipoyl(octanoyl) transferase activity
XcfCFBP6992P_05625	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
XcfCFBP6992P_05640	COG0583	DNA-binding transcription factor activity
XcfCFBP6992P_05650	COG1056	cytidyltransferase-related domain
XcfCFBP6992P_05650	COG1051	belongs to the nudix hydrolase family
XcfCFBP6992P_05685	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
XcfCFBP6992P_05690	COG0673	inositol 2-dehydrogenase activity
XcfCFBP6992P_05695	COG2823	Periplasmic or secreted lipoprotein
XcfCFBP6992P_05700	COG4251	negative regulation of phosphorylation
XcfCFBP6992P_05705	COG0784	Response regulator, receiver
XcfCFBP6992P_05710	COG4191	Histidine kinase
XcfCFBP6992P_05715	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XcfCFBP6992P_05770	COG1459	type II secretion system
XcfCFBP6992P_05790	COG4795	General secretion pathway protein
XcfCFBP6992P_05820	COG3250	beta-galactosidase activity
XcfCFBP6992P_05835	COG2188	Transcriptional regulator
XcfCFBP6992P_05845	COG1609	Transcriptional regulator
XcfCFBP6992P_05850	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XcfCFBP6992P_05855	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
XcfCFBP6992P_05870	COG0617	tRNA 3'-terminal CCA addition
XcfCFBP6992P_05875	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
XcfCFBP6992P_05880	COG1012	belongs to the aldehyde dehydrogenase family
XcfCFBP6992P_05885	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
XcfCFBP6992P_05900	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XcfCFBP6992P_05915	COG0218	Necessary for normal cell division and for the maintenance of normal septation
XcfCFBP6992P_05920	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XcfCFBP6992P_05940	COG2205	protein histidine kinase activity
XcfCFBP6992P_05970	COG3791	Glutathione-dependent formaldehyde-activating
XcfCFBP6992P_05985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XcfCFBP6992P_05995	COG0697	spore germination
XcfCFBP6992P_06005	COG0488	(ABC) transporter
XcfCFBP6992P_06015	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
XcfCFBP6992P_06020	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
XcfCFBP6992P_06030	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XcfCFBP6992P_06030	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XcfCFBP6992P_06050	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
XcfCFBP6992P_06055	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XcfCFBP6992P_06060	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
XcfCFBP6992P_06085	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
XcfCFBP6992P_06090	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
XcfCFBP6992P_06095	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
XcfCFBP6992P_06100	COG2205	protein histidine kinase activity
XcfCFBP6992P_06105	COG0745	RESPONSE REGULATOR receiver
XcfCFBP6992P_06110	COG0277	FAD linked oxidase domain protein
XcfCFBP6992P_06115	COG1988	membrane-bound metal-dependent
XcfCFBP6992P_06120	COG0792	nuclease activity
XcfCFBP6992P_06155	COG0275	rRNA processing
XcfCFBP6992P_06160	COG3116	cell division
XcfCFBP6992P_06175	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
XcfCFBP6992P_06180	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
XcfCFBP6992P_06185	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XcfCFBP6992P_06195	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
XcfCFBP6992P_06200	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XcfCFBP6992P_06205	COG1181	Belongs to the D-alanine--D-alanine ligase family
XcfCFBP6992P_06210	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
XcfCFBP6992P_06225	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
XcfCFBP6992P_06235	COG0739	heme binding
XcfCFBP6992P_06240	COG0653	protein targeting
XcfCFBP6992P_06245	COG0494	nUDIX hydrolase
XcfCFBP6992P_06255	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XcfCFBP6992P_06270	COG0604	alcohol dehydrogenase
XcfCFBP6992P_06270	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6992P_06270	COG3321	synthase
XcfCFBP6992P_06295	COG0366	Alpha amylase catalytic
XcfCFBP6992P_06330	COG2226	methyltransferase
XcfCFBP6992P_06335	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
XcfCFBP6992P_06345	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
XcfCFBP6992P_06385	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
XcfCFBP6992P_06395	COG4106	trans-aconitate 2-methyltransferase activity
XcfCFBP6992P_06400	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XcfCFBP6992P_06410	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XcfCFBP6992P_06415	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
XcfCFBP6992P_06425	COG0667	Aldo Keto reductase
XcfCFBP6992P_06455	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XcfCFBP6992P_06460	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
XcfCFBP6992P_06470	COG2175	clavaminate synthase activity
XcfCFBP6992P_06480	COG4181	ATPase activity
XcfCFBP6992P_06495	COG0642	Histidine kinase
XcfCFBP6992P_06505	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
XcfCFBP6992P_06525	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
XcfCFBP6992P_06530	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
XcfCFBP6992P_06545	COG3829	transcription factor binding
XcfCFBP6992P_06555	COG1116	anion transmembrane transporter activity
XcfCFBP6992P_06560	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XcfCFBP6992P_06570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XcfCFBP6992P_06575	COG0431	NADPH-dependent FMN reductase
XcfCFBP6992P_06595	COG0747	negative chemotaxis
XcfCFBP6992P_06605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XcfCFBP6992P_06615	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
XcfCFBP6992P_06620	COG2967	ApaG domain
XcfCFBP6992P_06625	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
XcfCFBP6992P_06630	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
XcfCFBP6992P_06635	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XcfCFBP6992P_06640	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
XcfCFBP6992P_06645	COG0123	including yeast histone deacetylase and acetoin utilization protein
XcfCFBP6992P_06650	COG2096	Adenosyltransferase
XcfCFBP6992P_06665	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XcfCFBP6992P_06670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XcfCFBP6992P_06700	COG3384	dioxygenase
XcfCFBP6992P_06705	COG0583	DNA-binding transcription factor activity
XcfCFBP6992P_06720	COG1024	Enoyl-CoA hydratase
XcfCFBP6992P_06750	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
XcfCFBP6992P_06775	COG0697	spore germination
XcfCFBP6992P_06785	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XcfCFBP6992P_06810	COG2197	response regulator
XcfCFBP6992P_06820	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XcfCFBP6992P_06830	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
XcfCFBP6992P_06835	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XcfCFBP6992P_06845	COG0583	DNA-binding transcription factor activity
XcfCFBP6992P_06850	COG3634	alkyl hydroperoxide reductase activity
XcfCFBP6992P_06860	COG2890	protein-(glutamine-N5) methyltransferase activity
XcfCFBP6992P_06880	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XcfCFBP6992P_06880	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XcfCFBP6992P_06910	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
XcfCFBP6992P_06935	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
XcfCFBP6992P_06950	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XcfCFBP6992P_06955	COG1404	Belongs to the peptidase S8 family
XcfCFBP6992P_06960	COG1404	Belongs to the peptidase S8 family
XcfCFBP6992P_06965	COG1404	Belongs to the peptidase S8 family
XcfCFBP6992P_06970	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
XcfCFBP6992P_06995	COG1295	ribonuclease BN
XcfCFBP6992P_07000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XcfCFBP6992P_07020	COG0521	Mo-molybdopterin cofactor biosynthetic process
XcfCFBP6992P_07030	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
XcfCFBP6992P_07035	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
XcfCFBP6992P_07045	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
XcfCFBP6992P_07050	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
XcfCFBP6992P_07060	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
XcfCFBP6992P_07065	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
XcfCFBP6992P_07070	COG0193	aminoacyl-tRNA hydrolase activity
XcfCFBP6992P_07075	COG0012	GTP binding
XcfCFBP6992P_07095	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XcfCFBP6992P_07110	COG0250	Participates in transcription elongation, termination and antitermination
XcfCFBP6992P_07115	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
XcfCFBP6992P_07120	COG0081	regulation of translation
XcfCFBP6992P_07125	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
XcfCFBP6992P_07130	COG0222	ribosome binding
XcfCFBP6992P_07135	COG0085	RNA polymerase activity
XcfCFBP6992P_07140	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
XcfCFBP6992P_07145	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
XcfCFBP6992P_07150	COG0049	tRNA binding
XcfCFBP6992P_07155	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
XcfCFBP6992P_07160	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XcfCFBP6992P_07165	COG0051	transcription antitermination factor activity, RNA binding
XcfCFBP6992P_07170	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
XcfCFBP6992P_07175	COG0088	Forms part of the polypeptide exit tunnel
XcfCFBP6992P_07180	COG0089	rRNA binding
XcfCFBP6992P_07185	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XcfCFBP6992P_07190	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
XcfCFBP6992P_07200	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
XcfCFBP6992P_07205	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
XcfCFBP6992P_07210	COG0255	Belongs to the universal ribosomal protein uL29 family
XcfCFBP6992P_07215	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
XcfCFBP6992P_07225	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
XcfCFBP6992P_07230	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
XcfCFBP6992P_07240	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
XcfCFBP6992P_07245	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
XcfCFBP6992P_07250	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
XcfCFBP6992P_07260	COG1841	ribosomal large subunit assembly
XcfCFBP6992P_07265	COG0200	Binds to the 23S rRNA
XcfCFBP6992P_07270	COG0201	protein transport
XcfCFBP6992P_07295	COG0203	ribosomal protein L17
XcfCFBP6992P_07300	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
XcfCFBP6992P_07320	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
XcfCFBP6992P_07335	COG0154	amidase activity
XcfCFBP6992P_07345	COG1217	gtp-binding protein TYPA
XcfCFBP6992P_07350	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XcfCFBP6992P_07355	COG0039	L-malate dehydrogenase activity
XcfCFBP6992P_07360	COG0625	glutathione transferase activity
XcfCFBP6992P_07375	COG0446	pyridine nucleotide-disulphide oxidoreductase
XcfCFBP6992P_07375	COG1902	pentaerythritol trinitrate reductase activity
XcfCFBP6992P_07410	COG0156	8-amino-7-oxononanoate synthase activity
XcfCFBP6992P_07415	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
XcfCFBP6992P_07420	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
XcfCFBP6992P_07425	COG4208	sulfate ABC transporter
XcfCFBP6992P_07430	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
XcfCFBP6992P_07460	COG0406	alpha-ribazole phosphatase activity
XcfCFBP6992P_07465	COG0285	dihydrofolate synthase activity
XcfCFBP6992P_07485	COG2833	Protein of unknown function (DUF455)
XcfCFBP6992P_07505	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XcfCFBP6992P_07510	COG0671	phosphoesterase, PA-phosphatase related
XcfCFBP6992P_07515	COG0438	transferase activity, transferring glycosyl groups
XcfCFBP6992P_07525	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
XcfCFBP6992P_07540	COG4783	chaperone-mediated protein folding
XcfCFBP6992P_07555	COG0473	3-isopropylmalate dehydrogenase activity
XcfCFBP6992P_07600	COG3328	transposase activity
XcfCFBP6992P_07750	COG4695	Portal protein
XcfCFBP6992P_07805	COG2201	protein-glutamate methylesterase activity
XcfCFBP6992P_07810	COG3852	Histidine kinase
XcfCFBP6992P_07820	COG0544	peptidyl-prolyl cis-trans isomerase activity
XcfCFBP6992P_07830	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
XcfCFBP6992P_07860	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XcfCFBP6992P_07870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XcfCFBP6992P_07880	COG0328	RNA-DNA hybrid ribonuclease activity
XcfCFBP6992P_07885	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XcfCFBP6992P_07890	COG0631	protein serine/threonine phosphatase activity
XcfCFBP6992P_07905	COG0859	PFAM glycosyl transferase family 9
XcfCFBP6992P_07910	COG3642	lipopolysaccharide core region biosynthetic process
XcfCFBP6992P_07915	COG1234	tRNA 3'-trailer cleavage
XcfCFBP6992P_07920	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
XcfCFBP6992P_07930	COG0315	cyclic pyranopterin monophosphate synthase activity
XcfCFBP6992P_07935	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
XcfCFBP6992P_07940	COG0314	molybdopterin synthase activity
XcfCFBP6992P_07960	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
XcfCFBP6992P_07965	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
XcfCFBP6992P_07970	COG0537	adenosine 5'-monophosphoramidase activity
XcfCFBP6992P_07990	COG0714	Associated with various cellular activities
XcfCFBP6992P_08015	COG0424	maF-like protein
XcfCFBP6992P_08020	COG1399	metal-binding, possibly nucleic acid-binding protein
XcfCFBP6992P_08030	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XcfCFBP6992P_08040	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XcfCFBP6992P_08060	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
XcfCFBP6992P_08065	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XcfCFBP6992P_08090	COG3829	transcription factor binding
XcfCFBP6992P_08105	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
XcfCFBP6992P_08135	COG2373	Large extracellular alpha-helical protein
XcfCFBP6992P_08155	COG4953	penicillin-binding protein 1C
XcfCFBP6992P_08165	COG0678	peroxiredoxin activity
XcfCFBP6992P_08185	COG0330	HflC and HflK could
XcfCFBP6992P_08190	COG0330	HflC and HflK could
XcfCFBP6992P_08200	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
XcfCFBP6992P_08205	COG0308	aminopeptidase N
XcfCFBP6992P_08215	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6992P_08220	COG1309	transcriptional regulator
XcfCFBP6992P_08295	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XcfCFBP6992P_08305	COG3387	PFAM Glycoside hydrolase 15-related
XcfCFBP6992P_08310	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6992P_08320	COG3537	Alpha-1,2-mannosidase
XcfCFBP6992P_08330	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6992P_08375	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XcfCFBP6992P_08380	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XcfCFBP6992P_08385	COG2080	2 iron, 2 sulfur cluster binding
XcfCFBP6992P_08420	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XcfCFBP6992P_08435	COG0587	DNA-directed DNA polymerase activity
XcfCFBP6992P_08450	COG1297	OPT oligopeptide transporter protein
XcfCFBP6992P_08465	COG1506	peptidase
XcfCFBP6992P_08465	COG0823	Involved in the tonB-independent uptake of proteins
XcfCFBP6992P_08485	COG1917	Cupin 2, conserved barrel domain protein
XcfCFBP6992P_08485	COG2207	Transcriptional regulator
XcfCFBP6992P_08510	COG0753	catalase activity
XcfCFBP6992P_08515	COG0656	L-ascorbic acid biosynthetic process
XcfCFBP6992P_08525	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XcfCFBP6992P_08525	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XcfCFBP6992P_08530	COG2814	Major facilitator Superfamily
XcfCFBP6992P_08545	COG2194	sulfuric ester hydrolase activity
XcfCFBP6992P_08560	COG0745	RESPONSE REGULATOR receiver
XcfCFBP6992P_08565	COG0642	Histidine kinase
XcfCFBP6992P_08575	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
XcfCFBP6992P_08580	COG2894	cell division
XcfCFBP6992P_08585	COG0850	regulation of cytokinetic process
XcfCFBP6992P_08600	COG4585	Histidine kinase
XcfCFBP6992P_08605	COG2197	response regulator
XcfCFBP6992P_08620	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
XcfCFBP6992P_08645	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
XcfCFBP6992P_08655	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
XcfCFBP6992P_08675	COG1946	Acyl-CoA thioesterase
XcfCFBP6992P_08690	COG0824	Thioesterase
XcfCFBP6992P_08695	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
XcfCFBP6992P_08700	COG0261	This protein binds to 23S rRNA in the presence of protein L20
XcfCFBP6992P_08705	COG0211	Belongs to the bacterial ribosomal protein bL27 family
XcfCFBP6992P_08710	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
XcfCFBP6992P_08715	COG0268	Binds directly to 16S ribosomal RNA
XcfCFBP6992P_08725	COG0196	riboflavin kinase activity
XcfCFBP6992P_08730	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
XcfCFBP6992P_08735	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
XcfCFBP6992P_08740	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
XcfCFBP6992P_08755	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XcfCFBP6992P_08760	COG1845	cytochrome c oxidase, subunit III
XcfCFBP6992P_08765	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
XcfCFBP6992P_08780	COG3152	Membrane
XcfCFBP6992P_08790	COG2207	Transcriptional regulator
XcfCFBP6992P_08795	COG0326	Molecular chaperone. Has ATPase activity
XcfCFBP6992P_08805	COG1366	Belongs to the anti-sigma-factor antagonist family
XcfCFBP6992P_08810	COG1366	Belongs to the anti-sigma-factor antagonist family
XcfCFBP6992P_08815	COG2172	sigma factor antagonist activity
XcfCFBP6992P_08840	COG4771	TonB-dependent receptor
XcfCFBP6992P_08850	COG5507	3-demethylubiquinone-9 3-methyltransferase
XcfCFBP6992P_08855	COG2205	protein histidine kinase activity
XcfCFBP6992P_08865	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XcfCFBP6992P_08870	COG4999	Histidine kinase
XcfCFBP6992P_08870	COG3437	response regulator, receiver
XcfCFBP6992P_08870	COG2205	protein histidine kinase activity
XcfCFBP6992P_08870	COG3850	Histidine kinase
XcfCFBP6992P_08875	COG0784	Response regulator, receiver
XcfCFBP6992P_08875	COG4191	Histidine kinase
XcfCFBP6992P_08900	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XcfCFBP6992P_08910	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XcfCFBP6992P_08920	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XcfCFBP6992P_08925	COG0228	four-way junction DNA binding
XcfCFBP6992P_08930	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
XcfCFBP6992P_08935	COG0336	Belongs to the RNA methyltransferase TrmD family
XcfCFBP6992P_08940	COG0335	large ribosomal subunit rRNA binding
XcfCFBP6992P_08945	COG0534	Mate efflux family protein
XcfCFBP6992P_08970	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
XcfCFBP6992P_08980	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
XcfCFBP6992P_08990	COG3209	COG3209 Rhs family protein
XcfCFBP6992P_09000	COG3209	COG3209 Rhs family protein
XcfCFBP6992P_09020	COG2963	transposase activity
XcfCFBP6992P_09035	COG3250	beta-galactosidase activity
XcfCFBP6992P_09040	COG3867	Arabinogalactan endo-beta-1,4-galactanase
XcfCFBP6992P_09060	COG1960	acyl-CoA dehydrogenase activity
XcfCFBP6992P_09065	COG1024	Enoyl-CoA hydratase
XcfCFBP6992P_09070	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
XcfCFBP6992P_09100	COG0457	Tetratricopeptide repeat
XcfCFBP6992P_09110	COG1024	Enoyl-CoA hydratase
XcfCFBP6992P_09110	COG1250	3-hydroxyacyl-CoA dehydrogenase
XcfCFBP6992P_09125	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XcfCFBP6992P_09130	COG0481	GTPase activity
XcfCFBP6992P_09145	COG0571	ribonuclease III activity
XcfCFBP6992P_09150	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
XcfCFBP6992P_09155	COG1381	Involved in DNA repair and RecF pathway recombination
XcfCFBP6992P_09165	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
XcfCFBP6992P_09170	COG2954	triphosphatase activity
XcfCFBP6992P_09175	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
XcfCFBP6992P_09180	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
XcfCFBP6992P_09185	COG3046	protein related to deoxyribodipyrimidine photolyase
XcfCFBP6992P_09190	COG1472	Belongs to the glycosyl hydrolase 3 family
XcfCFBP6992P_09195	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
XcfCFBP6992P_09200	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
XcfCFBP6992P_09205	COG1278	Cold shock
XcfCFBP6992P_09210	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XcfCFBP6992P_09220	COG1201	RNA secondary structure unwinding
XcfCFBP6992P_09225	COG1793	dna ligase
XcfCFBP6992P_09235	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XcfCFBP6992P_09235	COG1793	dna ligase
XcfCFBP6992P_09265	COG0183	Belongs to the thiolase family
XcfCFBP6992P_09285	COG1451	nucleotide metabolic process
XcfCFBP6992P_09290	COG5487	UPF0391 membrane protein
XcfCFBP6992P_09300	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XcfCFBP6992P_09320	COG1077	Cell shape determining protein MreB Mrl
XcfCFBP6992P_09325	COG1047	Peptidyl-prolyl cis-trans
XcfCFBP6992P_09335	COG2824	Alkylphosphonate utilization operon protein PhnA
XcfCFBP6992P_09345	COG1902	pentaerythritol trinitrate reductase activity
XcfCFBP6992P_09350	COG2814	Major facilitator Superfamily
XcfCFBP6992P_09380	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
XcfCFBP6992P_09380	COG0392	lysyltransferase activity
XcfCFBP6992P_09390	COG0251	oxidation-reduction process
XcfCFBP6992P_09395	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XcfCFBP6992P_09410	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XcfCFBP6992P_09435	COG1595	DNA-templated transcription, initiation
XcfCFBP6992P_09460	COG2878	Part of a membrane complex involved in electron transport
XcfCFBP6992P_09470	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XcfCFBP6992P_09470	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XcfCFBP6992P_09485	COG1131	(ABC) transporter
XcfCFBP6992P_09490	COG0346	lactoylglutathione lyase activity
XcfCFBP6992P_09495	COG0833	amino acid
XcfCFBP6992P_09500	COG2040	homocysteine
XcfCFBP6992P_09510	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XcfCFBP6992P_09540	COG1695	Transcriptional regulator
XcfCFBP6992P_09560	COG1981	membrane
XcfCFBP6992P_09575	COG0825	malonyl-CoA metabolic process
XcfCFBP6992P_09590	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XcfCFBP6992P_09595	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XcfCFBP6992P_09600	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XcfCFBP6992P_09605	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XcfCFBP6992P_09620	COG0750	zinc metalloprotease
XcfCFBP6992P_09625	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
XcfCFBP6992P_09630	COG0575	Belongs to the CDS family
XcfCFBP6992P_09635	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
XcfCFBP6992P_09640	COG0233	cytoplasmic translational termination
XcfCFBP6992P_09645	COG0528	UMP kinase activity
XcfCFBP6992P_09655	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
XcfCFBP6992P_09660	COG0052	Belongs to the universal ribosomal protein uS2 family
XcfCFBP6992P_09700	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
XcfCFBP6992P_09710	COG1393	Belongs to the ArsC family
XcfCFBP6992P_09715	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XcfCFBP6992P_09720	COG0367	asparagine synthase
XcfCFBP6992P_09730	COG4774	siderophore transport
XcfCFBP6992P_09745	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
XcfCFBP6992P_09775	COG1566	PFAM secretion protein HlyD family protein
XcfCFBP6992P_09780	COG2814	Major facilitator Superfamily
XcfCFBP6992P_09830	COG0339	signal peptide processing
XcfCFBP6992P_09840	COG0386	Belongs to the glutathione peroxidase family
XcfCFBP6992P_09895	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
XcfCFBP6992P_09900	COG0084	hydrolase, TatD family'
XcfCFBP6992P_09915	COG1960	acyl-CoA dehydrogenase activity
XcfCFBP6992P_09935	COG0367	asparagine synthase
XcfCFBP6992P_09945	COG0305	Participates in initiation and elongation during chromosome replication
XcfCFBP6992P_09950	COG0415	Belongs to the DNA photolyase family
XcfCFBP6992P_09960	COG0583	DNA-binding transcription factor activity
XcfCFBP6992P_10005	COG3706	GGDEF domain
XcfCFBP6992P_10115	COG2003	Belongs to the UPF0758 family
XcfCFBP6992P_10210	COG3328	transposase activity
XcfCFBP6992P_10230	COG2814	Major facilitator Superfamily
XcfCFBP6992P_10300	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
XcfCFBP6992P_10315	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XcfCFBP6992P_10325	COG0497	DNA recombination
XcfCFBP6992P_10330	COG1420	regulation of RNA biosynthetic process
XcfCFBP6992P_10335	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XcfCFBP6992P_10340	COG0443	Heat shock 70 kDa protein
XcfCFBP6992P_10345	COG0484	heat shock protein binding
XcfCFBP6992P_10355	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
XcfCFBP6992P_10390	COG0583	DNA-binding transcription factor activity
XcfCFBP6992P_10395	COG1132	(ABC) transporter
XcfCFBP6992P_10420	COG0567	Dehydrogenase, E1 component
XcfCFBP6992P_10430	COG2850	peptidyl-arginine hydroxylation
XcfCFBP6992P_10450	COG1253	flavin adenine dinucleotide binding
XcfCFBP6992P_10485	COG1131	(ABC) transporter
XcfCFBP6992P_10490	COG1725	Transcriptional regulator
XcfCFBP6992P_10500	COG0386	Belongs to the glutathione peroxidase family
XcfCFBP6992P_10515	COG2900	Belongs to the SlyX family
XcfCFBP6992P_10540	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XcfCFBP6992P_10550	COG1410	methionine synthase
XcfCFBP6992P_10550	COG0646	methionine synthase
XcfCFBP6992P_10555	COG0646	methionine synthase
XcfCFBP6992P_10555	COG1410	methionine synthase
XcfCFBP6992P_10560	COG2226	methyltransferase
XcfCFBP6992P_10565	COG1960	acyl-CoA dehydrogenase activity
XcfCFBP6992P_10580	COG1960	acyl-CoA dehydrogenase activity
XcfCFBP6992P_10605	COG0557	exoribonuclease II activity
XcfCFBP6992P_10615	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XcfCFBP6992P_10625	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XcfCFBP6992P_10635	COG0704	Plays a role in the regulation of phosphate uptake
XcfCFBP6992P_10640	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
XcfCFBP6992P_10645	COG0581	inorganic phosphate transmembrane transporter activity
XcfCFBP6992P_10650	COG0573	inorganic phosphate transmembrane transporter activity
XcfCFBP6992P_10655	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XcfCFBP6992P_10680	COG0659	secondary active sulfate transmembrane transporter activity
XcfCFBP6992P_10685	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
XcfCFBP6992P_10695	COG1024	Enoyl-CoA hydratase
XcfCFBP6992P_10705	COG0494	nUDIX hydrolase
XcfCFBP6992P_10740	COG0488	(ABC) transporter
XcfCFBP6992P_10750	COG0116	Belongs to the methyltransferase superfamily
XcfCFBP6992P_10750	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XcfCFBP6992P_10755	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
XcfCFBP6992P_10775	COG2925	Exonuclease
XcfCFBP6992P_10780	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XcfCFBP6992P_10785	COG3844	kynureninase activity
XcfCFBP6992P_10795	COG0662	Cupin 2, conserved barrel domain protein
XcfCFBP6992P_10800	COG0288	reversible hydration of carbon dioxide
XcfCFBP6992P_10885	COG0017	Asparaginyl-tRNA synthetase
XcfCFBP6992P_10895	COG0316	Belongs to the HesB IscA family
XcfCFBP6992P_10900	COG0360	Binds together with S18 to 16S ribosomal RNA
XcfCFBP6992P_10905	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
XcfCFBP6992P_10910	COG0359	binds to the 23S rRNA
XcfCFBP6992P_10925	COG3115	cell septum assembly
XcfCFBP6992P_10935	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XcfCFBP6992P_10945	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
XcfCFBP6992P_10960	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
XcfCFBP6992P_10970	COG4993	Dehydrogenase
XcfCFBP6992P_10980	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
XcfCFBP6992P_10990	COG2986	histidine ammonia-lyase
XcfCFBP6992P_10995	COG1228	amidohydrolase
XcfCFBP6992P_11035	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
XcfCFBP6992P_11040	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XcfCFBP6992P_11045	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
XcfCFBP6992P_11050	COG0077	Prephenate dehydratase
XcfCFBP6992P_11050	COG1605	Chorismate mutase
XcfCFBP6992P_11055	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
XcfCFBP6992P_11070	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
XcfCFBP6992P_11075	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XcfCFBP6992P_11080	COG0583	DNA-binding transcription factor activity
XcfCFBP6992P_11145	COG0840	transmembrane signaling receptor activity
XcfCFBP6992P_11175	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
XcfCFBP6992P_11180	COG0784	Response regulator, receiver
XcfCFBP6992P_11180	COG4191	Histidine kinase
XcfCFBP6992P_11195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XcfCFBP6992P_11205	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
XcfCFBP6992P_11215	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XcfCFBP6992P_11230	COG1595	DNA-templated transcription, initiation
XcfCFBP6992P_11285	COG2244	polysaccharide biosynthetic process
XcfCFBP6992P_11315	COG2264	protein methyltransferase activity
XcfCFBP6992P_11340	COG1136	(ABC) transporter
XcfCFBP6992P_11350	COG0477	Major facilitator Superfamily
XcfCFBP6992P_11355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XcfCFBP6992P_11370	COG1253	flavin adenine dinucleotide binding
XcfCFBP6992P_11385	COG0306	phosphate transporter
XcfCFBP6992P_11410	COG0504	CTP synthase activity
XcfCFBP6992P_11425	COG0148	phosphopyruvate hydratase activity
XcfCFBP6992P_11430	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
XcfCFBP6992P_11435	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
XcfCFBP6992P_11440	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
XcfCFBP6992P_11445	COG0585	pseudouridine synthase activity
XcfCFBP6992P_11450	COG2840	Smr protein MutS2
XcfCFBP6992P_11455	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
XcfCFBP6992P_11460	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XcfCFBP6992P_11465	COG1238	metal cluster binding
XcfCFBP6992P_11480	COG1534	Rna-binding protein
XcfCFBP6992P_11485	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
XcfCFBP6992P_11495	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
XcfCFBP6992P_11500	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
XcfCFBP6992P_11510	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
XcfCFBP6992P_11515	COG1546	Belongs to the CinA family
XcfCFBP6992P_11525	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XcfCFBP6992P_11530	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
XcfCFBP6992P_11540	COG2137	regulation of response to DNA damage stimulus
XcfCFBP6992P_11545	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
XcfCFBP6992P_11550	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
XcfCFBP6992P_11570	COG1741	Belongs to the pirin family
XcfCFBP6992P_11575	COG0583	DNA-binding transcription factor activity
XcfCFBP6992P_11600	COG0351	phosphomethylpyrimidine kinase
XcfCFBP6992P_11615	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
XcfCFBP6992P_11620	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XcfCFBP6992P_11635	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XcfCFBP6992P_11645	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
XcfCFBP6992P_11650	COG3734	2-keto-3-deoxy-galactonokinase
XcfCFBP6992P_11660	COG4948	Mandelate Racemase Muconate Lactonizing
XcfCFBP6992P_11665	COG0800	Aldolase
XcfCFBP6992P_11705	COG1501	Belongs to the glycosyl hydrolase 31 family
XcfCFBP6992P_11715	COG1070	Carbohydrate kinase
XcfCFBP6992P_11720	COG2115	Belongs to the xylose isomerase family
XcfCFBP6992P_11725	COG0477	Major facilitator Superfamily
XcfCFBP6992P_11740	COG0860	N-Acetylmuramoyl-L-alanine amidase
XcfCFBP6992P_11745	COG1469	GTP cyclohydrolase I activity
XcfCFBP6992P_11765	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
XcfCFBP6992P_11770	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
XcfCFBP6992P_11775	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
XcfCFBP6992P_11800	COG1472	Belongs to the glycosyl hydrolase 3 family
XcfCFBP6992P_11815	COG3706	GGDEF domain
XcfCFBP6992P_11815	COG4251	negative regulation of phosphorylation
XcfCFBP6992P_11815	COG5001	Diguanylate cyclase
XcfCFBP6992P_11815	COG2203	Gaf domain
XcfCFBP6992P_11820	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XcfCFBP6992P_11825	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
XcfCFBP6992P_11835	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
XcfCFBP6992P_11840	COG0671	phosphoesterase, PA-phosphatase related
XcfCFBP6992P_11850	COG1794	racemase activity, acting on amino acids and derivatives
XcfCFBP6992P_11860	COG0697	spore germination
XcfCFBP6992P_11865	COG0812	UDP-N-acetylmuramate dehydrogenase activity
XcfCFBP6992P_11870	COG0167	dihydroorotate dehydrogenase activity
XcfCFBP6992P_11885	COG1012	belongs to the aldehyde dehydrogenase family
XcfCFBP6992P_11905	COG1215	transferase activity, transferring glycosyl groups
XcfCFBP6992P_11910	COG0726	polysaccharide deacetylase
XcfCFBP6992P_11910	COG1649	PFAM Uncharacterised BCR, COG1649
XcfCFBP6992P_11930	COG3328	transposase activity
XcfCFBP6992P_11935	COG3210	domain, Protein
XcfCFBP6992P_12005	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XcfCFBP6992P_12010	COG0124	histidyl-tRNA synthetase
XcfCFBP6992P_12020	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
XcfCFBP6992P_12025	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
XcfCFBP6992P_12030	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XcfCFBP6992P_12035	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
XcfCFBP6992P_12035	COG0131	Imidazoleglycerol-phosphate dehydratase
XcfCFBP6992P_12040	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
XcfCFBP6992P_12045	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
XcfCFBP6992P_12050	COG0107	imidazoleglycerol-phosphate synthase activity
XcfCFBP6992P_12055	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
XcfCFBP6992P_12055	COG0140	phosphoribosyl-ATP diphosphatase activity
XcfCFBP6992P_12070	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
XcfCFBP6992P_12075	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
XcfCFBP6992P_12080	COG0235	Class ii aldolase
XcfCFBP6992P_12085	COG0531	amino acid
XcfCFBP6992P_12090	COG0531	amino acid
XcfCFBP6992P_12100	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XcfCFBP6992P_12105	COG0277	FAD linked oxidase domain protein
XcfCFBP6992P_12125	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XcfCFBP6992P_12170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XcfCFBP6992P_12175	COG2258	MOSC domain
XcfCFBP6992P_12180	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
XcfCFBP6992P_12185	COG0505	Belongs to the CarA family
XcfCFBP6992P_12195	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
XcfCFBP6992P_12200	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XcfCFBP6992P_12210	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
XcfCFBP6992P_12220	COG3279	Response regulator of the LytR AlgR family
XcfCFBP6992P_12230	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
XcfCFBP6992P_12240	COG2205	protein histidine kinase activity
XcfCFBP6992P_12240	COG0784	Response regulator, receiver
XcfCFBP6992P_12240	COG2198	Histidine kinase
XcfCFBP6992P_12245	COG0784	Response regulator, receiver
XcfCFBP6992P_12245	COG2205	protein histidine kinase activity
XcfCFBP6992P_12245	COG2198	Histidine kinase
XcfCFBP6992P_12250	COG1024	Enoyl-CoA hydratase
XcfCFBP6992P_12255	COG0318	PFAM AMP-dependent synthetase and ligase
XcfCFBP6992P_12285	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XcfCFBP6992P_12295	COG2201	protein-glutamate methylesterase activity
XcfCFBP6992P_12300	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
XcfCFBP6992P_12310	COG0840	transmembrane signaling receptor activity
XcfCFBP6992P_12320	COG0835	chemotaxis
XcfCFBP6992P_12345	COG0840	transmembrane signaling receptor activity
XcfCFBP6992P_12350	COG0840	transmembrane signaling receptor activity
XcfCFBP6992P_12360	COG0840	transmembrane signaling receptor activity
XcfCFBP6992P_12370	COG0840	transmembrane signaling receptor activity
XcfCFBP6992P_12375	COG0840	transmembrane signaling receptor activity
XcfCFBP6992P_12380	COG0840	transmembrane signaling receptor activity
XcfCFBP6992P_12385	COG0840	transmembrane signaling receptor activity
XcfCFBP6992P_12400	COG0840	transmembrane signaling receptor activity
XcfCFBP6992P_12425	COG0745	RESPONSE REGULATOR receiver
XcfCFBP6992P_12435	COG0835	chemotaxis
XcfCFBP6992P_12445	COG1360	Flagellar Motor Protein
XcfCFBP6992P_12450	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
XcfCFBP6992P_12475	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
XcfCFBP6992P_12535	COG0643	Histidine kinase
XcfCFBP6992P_12535	COG0784	Response regulator, receiver
XcfCFBP6992P_12535	COG2198	Histidine kinase
XcfCFBP6992P_12595	COG1684	flagellar biosynthetic protein fliR
XcfCFBP6992P_12610	COG3190	flagellar
XcfCFBP6992P_12660	COG1677	Flagellar hook-basal body complex protein FliE
XcfCFBP6992P_12695	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6992P_12700	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6992P_12705	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XcfCFBP6992P_12725	COG2201	protein-glutamate methylesterase activity
XcfCFBP6992P_12755	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
XcfCFBP6992P_12765	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XcfCFBP6992P_12775	COG1705	Flagellar rod assembly protein muramidase FlgJ
XcfCFBP6992P_12775	COG3951	Flagellar rod assembly protein muramidase FlgJ
XcfCFBP6992P_12780	COG1706	bacterial-type flagellum-dependent cell motility
XcfCFBP6992P_12785	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
XcfCFBP6992P_12800	COG4787	bacterial-type flagellum-dependent cell motility
XcfCFBP6992P_12810	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
XcfCFBP6992P_12815	COG1558	bacterial-type flagellum-dependent cell motility
XcfCFBP6992P_12825	COG0784	Response regulator, receiver
XcfCFBP6992P_12825	COG0835	chemotaxis
XcfCFBP6992P_12845	COG5002	protein histidine kinase activity
XcfCFBP6992P_12875	COG2915	High frequency lysogenization protein hflD homolog
XcfCFBP6992P_12880	COG0482	sulfurtransferase activity
XcfCFBP6992P_12895	COG0542	response to heat
XcfCFBP6992P_12905	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
XcfCFBP6992P_12915	COG0492	ferredoxin-NADP+ reductase activity
XcfCFBP6992P_12920	COG1674	ftsk spoiiie
XcfCFBP6992P_12930	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
XcfCFBP6992P_12940	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
XcfCFBP6992P_12945	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
XcfCFBP6992P_12955	COG0183	Belongs to the thiolase family
XcfCFBP6992P_12960	COG1250	3-hydroxyacyl-CoA dehydrogenase
XcfCFBP6992P_12960	COG1024	Enoyl-CoA hydratase
XcfCFBP6992P_12975	COG0820	rRNA (adenine-C2-)-methyltransferase activity
XcfCFBP6992P_12985	COG1426	Protein conserved in bacteria
XcfCFBP6992P_12995	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XcfCFBP6992P_13000	COG1160	GTP binding
XcfCFBP6992P_13005	COG0303	'Molybdopterin
XcfCFBP6992P_13010	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XcfCFBP6992P_13045	COG0708	Exodeoxyribonuclease III
XcfCFBP6992P_13055	COG0303	'Molybdopterin
XcfCFBP6992P_13060	COG0746	molybdenum cofactor guanylyltransferase activity
XcfCFBP6992P_13090	COG1914	H( )-stimulated, divalent metal cation uptake system
XcfCFBP6992P_13110	COG0668	transmembrane transport
XcfCFBP6992P_13120	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
XcfCFBP6992P_13135	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6992P_13140	COG1183	phosphatidylcholine synthase activity
XcfCFBP6992P_13150	COG3243	poly(R)-hydroxyalkanoic acid synthase
XcfCFBP6992P_13165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XcfCFBP6992P_13165	COG0723	plastoquinol--plastocyanin reductase activity
XcfCFBP6992P_13175	COG2183	response to ionizing radiation
XcfCFBP6992P_13180	COG2205	protein histidine kinase activity
XcfCFBP6992P_13180	COG0784	Response regulator, receiver
XcfCFBP6992P_13240	COG0800	Aldolase
XcfCFBP6992P_13245	COG0129	dihydroxy-acid dehydratase activity
XcfCFBP6992P_13250	COG0363	glucosamine-6-phosphate deaminase activity
XcfCFBP6992P_13255	COG0837	glucose binding
XcfCFBP6992P_13260	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XcfCFBP6992P_13270	COG0354	folic acid binding
XcfCFBP6992P_13285	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
XcfCFBP6992P_13300	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
XcfCFBP6992P_13305	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
XcfCFBP6992P_13315	COG4591	ABC-type transport system involved in lipoprotein release permease component
XcfCFBP6992P_13320	COG1136	(ABC) transporter
XcfCFBP6992P_13335	COG0811	peptide transport
XcfCFBP6992P_13340	COG0848	biopolymer transport protein
XcfCFBP6992P_13345	COG1132	(ABC) transporter
XcfCFBP6992P_13350	COG1663	tetraacyldisaccharide 4'-kinase activity
XcfCFBP6992P_13355	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
XcfCFBP6992P_13360	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
XcfCFBP6992P_13370	COG0322	excinuclease ABC activity
XcfCFBP6992P_13375	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XcfCFBP6992P_13385	COG0582	viral genome integration into host DNA
XcfCFBP6992P_13400	COG0583	DNA-binding transcription factor activity
XcfCFBP6992P_13645	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6992P_13655	COG4221	oxidoreductase activity
XcfCFBP6992P_13660	COG3328	transposase activity
XcfCFBP6992P_13665	COG0300	oxidoreductase activity
XcfCFBP6992P_13675	COG0560	Phosphoserine phosphatase
XcfCFBP6992P_13675	COG3830	Belongs to the UPF0237 family
XcfCFBP6992P_13710	COG2003	Belongs to the UPF0758 family
XcfCFBP6992P_13860	COG3328	transposase activity
XcfCFBP6992P_13910	COG0270	DNA (cytosine-5-)-methyltransferase activity
XcfCFBP6992P_13915	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XcfCFBP6992P_13920	COG0629	single-stranded DNA binding
XcfCFBP6992P_13980	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
XcfCFBP6992P_14015	COG0464	growth
XcfCFBP6992P_14040	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
XcfCFBP6992P_14060	COG1054	Belongs to the UPF0176 family
XcfCFBP6992P_14070	COG1530	ribonuclease E activity
XcfCFBP6992P_14080	COG3064	Membrane
XcfCFBP6992P_14085	COG0428	transporter
XcfCFBP6992P_14095	COG2154	pterin-4-alpha-carbinolamine dehydratase
XcfCFBP6992P_14100	COG0316	Belongs to the HesB IscA family
XcfCFBP6992P_14100	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
XcfCFBP6992P_14150	COG2226	methyltransferase
XcfCFBP6992P_14150	COG1073	alpha beta
XcfCFBP6992P_14155	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
XcfCFBP6992P_14160	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6992P_14180	COG1136	(ABC) transporter
XcfCFBP6992P_14185	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XcfCFBP6992P_14190	COG4221	oxidoreductase activity
XcfCFBP6992P_14190	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6992P_14190	COG3321	synthase
XcfCFBP6992P_14190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XcfCFBP6992P_14195	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XcfCFBP6992P_14195	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XcfCFBP6992P_14195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XcfCFBP6992P_14195	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6992P_14195	COG3321	synthase
XcfCFBP6992P_14320	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XcfCFBP6992P_14320	COG3321	synthase
XcfCFBP6992P_14320	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XcfCFBP6992P_14320	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XcfCFBP6992P_14320	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6992P_14435	COG0583	DNA-binding transcription factor activity
XcfCFBP6992P_14470	COG3220	belongs to the UPF0276 family
XcfCFBP6992P_14495	COG3920	Histidine kinase
XcfCFBP6992P_14505	COG1238	metal cluster binding
XcfCFBP6992P_14535	COG3279	Response regulator of the LytR AlgR family
XcfCFBP6992P_14540	COG3275	phosphorelay sensor kinase activity
XcfCFBP6992P_14580	COG4566	intracellular signal transduction
XcfCFBP6992P_14590	COG5001	Diguanylate cyclase
XcfCFBP6992P_14610	COG3685	Protein conserved in bacteria
XcfCFBP6992P_14630	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XcfCFBP6992P_14630	COG1648	precorrin-2 dehydrogenase activity
XcfCFBP6992P_14645	COG2814	Major facilitator Superfamily
XcfCFBP6992P_14660	COG1335	isochorismatase
XcfCFBP6992P_14675	COG2197	response regulator
XcfCFBP6992P_14690	COG0583	DNA-binding transcription factor activity
XcfCFBP6992P_14695	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XcfCFBP6992P_14700	COG3002	Belongs to the UPF0753 family
XcfCFBP6992P_14705	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XcfCFBP6992P_14705	COG0519	Catalyzes the synthesis of GMP from XMP
XcfCFBP6992P_14715	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
XcfCFBP6992P_14730	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XcfCFBP6992P_14730	COG0475	glutathione-regulated potassium exporter activity
XcfCFBP6992P_14735	COG1210	Utp--glucose-1-phosphate uridylyltransferase
XcfCFBP6992P_14745	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XcfCFBP6992P_14750	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
XcfCFBP6992P_14760	COG0776	regulation of translation
XcfCFBP6992P_14765	COG0539	negative regulation of cytoplasmic translation
XcfCFBP6992P_14770	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
XcfCFBP6992P_14790	COG2957	Belongs to the agmatine deiminase family
XcfCFBP6992P_14795	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XcfCFBP6992P_14820	COG0395	ABC-type sugar transport system, permease component
XcfCFBP6992P_14825	COG1175	transmembrane transport
XcfCFBP6992P_14855	COG2350	Protein conserved in bacteria
XcfCFBP6992P_14860	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
XcfCFBP6992P_14865	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
XcfCFBP6992P_14870	COG1187	pseudouridine synthase activity
XcfCFBP6992P_14890	COG0436	Aminotransferase
XcfCFBP6992P_14895	COG4133	protoheme IX ABC transporter activity
XcfCFBP6992P_14915	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
XcfCFBP6992P_14920	COG1138	Cytochrome C-type biogenesis protein
XcfCFBP6992P_14940	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XcfCFBP6992P_14945	COG1278	Cold shock
XcfCFBP6992P_14950	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
XcfCFBP6992P_14955	COG4988	ABC transporter
XcfCFBP6992P_14965	COG1294	oxidase, subunit
XcfCFBP6992P_14995	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
XcfCFBP6992P_15000	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
XcfCFBP6992P_15010	COG0165	Argininosuccinate lyase
XcfCFBP6992P_15015	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
XcfCFBP6992P_15025	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XcfCFBP6992P_15030	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XcfCFBP6992P_15040	COG0137	argininosuccinate synthase activity
XcfCFBP6992P_15045	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
XcfCFBP6992P_15055	COG0215	cysteine-tRNA ligase activity
XcfCFBP6992P_15060	COG2166	iron-sulfur cluster assembly
XcfCFBP6992P_15075	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
XcfCFBP6992P_15080	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XcfCFBP6992P_15100	COG4302	ethanolamine ammonia-lyase activity
XcfCFBP6992P_15150	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XcfCFBP6992P_15155	COG0402	S-adenosylhomocysteine deaminase activity
XcfCFBP6992P_15165	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XcfCFBP6992P_15170	COG1509	lysine 2,3-aminomutase activity
XcfCFBP6992P_15175	COG3300	MHYT domain
XcfCFBP6992P_15175	COG5001	Diguanylate cyclase
XcfCFBP6992P_15190	COG0483	inositol monophosphate 1-phosphatase activity
XcfCFBP6992P_15195	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XcfCFBP6992P_15215	COG0488	(ABC) transporter
XcfCFBP6992P_15220	COG0513	Belongs to the DEAD box helicase family
XcfCFBP6992P_15225	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
XcfCFBP6992P_15230	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
XcfCFBP6992P_15240	COG0625	glutathione transferase activity
XcfCFBP6992P_15250	COG4681	YaeQ
XcfCFBP6992P_15255	COG2081	HI0933 family
XcfCFBP6992P_15265	COG0501	Belongs to the peptidase M48B family
XcfCFBP6992P_15270	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XcfCFBP6992P_15275	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6992P_15300	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
XcfCFBP6992P_15305	COG0860	N-Acetylmuramoyl-L-alanine amidase
XcfCFBP6992P_15310	COG0802	atpase or kinase
XcfCFBP6992P_15315	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
XcfCFBP6992P_15315	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XcfCFBP6992P_15320	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XcfCFBP6992P_15325	COG1570	exodeoxyribonuclease VII activity
XcfCFBP6992P_15335	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XcfCFBP6992P_15380	COG0835	chemotaxis
XcfCFBP6992P_15385	COG0840	transmembrane signaling receptor activity
XcfCFBP6992P_15390	COG2094	Belongs to the DNA glycosylase MPG family
XcfCFBP6992P_15395	COG1201	RNA secondary structure unwinding
XcfCFBP6992P_15415	COG2969	positive regulation of protein catabolic process
XcfCFBP6992P_15420	COG0625	glutathione transferase activity
XcfCFBP6992P_15425	COG2857	Cytochrome c1
XcfCFBP6992P_15430	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
XcfCFBP6992P_15435	COG0723	plastoquinol--plastocyanin reductase activity
XcfCFBP6992P_15445	COG0741	lytic transglycosylase activity
XcfCFBP6992P_15460	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XcfCFBP6992P_15465	COG1702	phosphate starvation-inducible protein PhoH
XcfCFBP6992P_15475	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
XcfCFBP6992P_15485	COG4535	Mg2 and Co2 transporter CorC
XcfCFBP6992P_15500	COG1012	belongs to the aldehyde dehydrogenase family
XcfCFBP6992P_15505	COG1177	transmembrane transport
XcfCFBP6992P_15510	COG1176	ABC-type spermidine putrescine transport system, permease component I
XcfCFBP6992P_15520	COG3842	ATPase activity
XcfCFBP6992P_15540	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
XcfCFBP6992P_15555	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
XcfCFBP6992P_15560	COG0174	glutamine synthetase
XcfCFBP6992P_15565	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XcfCFBP6992P_15575	COG2703	oxygen carrier activity
XcfCFBP6992P_15580	COG0477	Major facilitator Superfamily
XcfCFBP6992P_15590	COG0243	molybdopterin cofactor binding
XcfCFBP6992P_15595	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
XcfCFBP6992P_15600	COG2223	nitrite transmembrane transporter activity
XcfCFBP6992P_15615	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XcfCFBP6992P_15625	COG2733	membrane
XcfCFBP6992P_15630	COG5002	protein histidine kinase activity
XcfCFBP6992P_15630	COG2205	protein histidine kinase activity
XcfCFBP6992P_15630	COG0784	Response regulator, receiver
XcfCFBP6992P_15645	COG0477	Major facilitator Superfamily
XcfCFBP6992P_15675	COG2902	Dehydrogenase
XcfCFBP6992P_15685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcfCFBP6992P_15690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcfCFBP6992P_15695	COG1609	Transcriptional regulator
XcfCFBP6992P_15700	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
XcfCFBP6992P_15700	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XcfCFBP6992P_15705	COG1105	Belongs to the carbohydrate kinase PfkB family
XcfCFBP6992P_15710	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XcfCFBP6992P_15710	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XcfCFBP6992P_15755	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XcfCFBP6992P_15765	COG1862	Preprotein translocase
XcfCFBP6992P_15770	COG0343	queuine tRNA-ribosyltransferase activity
XcfCFBP6992P_15775	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
XcfCFBP6992P_15810	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
XcfCFBP6992P_15815	COG3291	Pkd domain containing protein
XcfCFBP6992P_15820	COG0405	Gamma-glutamyltransferase
XcfCFBP6992P_15825	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XcfCFBP6992P_15840	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
XcfCFBP6992P_15845	COG0742	ribosomal rna small subunit methyltransferase
XcfCFBP6992P_15850	COG0326	Molecular chaperone. Has ATPase activity
XcfCFBP6992P_15935	COG0531	amino acid
XcfCFBP6992P_15950	COG0006	proline dipeptidase activity
XcfCFBP6992P_15960	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XcfCFBP6992P_15975	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XcfCFBP6992P_15980	COG3938	Belongs to the proline racemase family
XcfCFBP6992P_15990	COG0552	protein localization to endoplasmic reticulum
XcfCFBP6992P_15995	COG1194	a g-specific adenine glycosylase
XcfCFBP6992P_16000	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
XcfCFBP6992P_16005	COG0784	Response regulator, receiver
XcfCFBP6992P_16005	COG4191	Histidine kinase
XcfCFBP6992P_16020	COG0322	excinuclease ABC activity
XcfCFBP6992P_16035	COG3040	lipid binding
XcfCFBP6992P_16045	COG1960	acyl-CoA dehydrogenase activity
XcfCFBP6992P_16055	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
XcfCFBP6992P_16075	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XcfCFBP6992P_16080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XcfCFBP6992P_16085	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XcfCFBP6992P_16110	COG0438	transferase activity, transferring glycosyl groups
XcfCFBP6992P_16120	COG0438	transferase activity, transferring glycosyl groups
XcfCFBP6992P_16125	COG0438	transferase activity, transferring glycosyl groups
XcfCFBP6992P_16175	COG0072	phenylalanine-tRNA ligase activity
XcfCFBP6992P_16175	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XcfCFBP6992P_16180	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
XcfCFBP6992P_16195	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
XcfCFBP6992P_16200	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
XcfCFBP6992P_16215	COG2190	(PTS) system
XcfCFBP6992P_16215	COG2211	Major facilitator Superfamily
XcfCFBP6992P_16225	COG1082	Xylose isomerase domain protein TIM barrel
XcfCFBP6992P_16240	COG0366	Alpha amylase catalytic
XcfCFBP6992P_16350	COG3702	type iv secretory pathway
XcfCFBP6992P_16370	COG2948	multi-organism process
XcfCFBP6992P_16390	COG3505	Type IV secretory pathway VirD4
XcfCFBP6992P_16405	COG0556	nucleotide-excision repair
XcfCFBP6992P_16410	COG4969	Belongs to the N-Me-Phe pilin family
XcfCFBP6992P_16445	COG4969	Belongs to the N-Me-Phe pilin family
XcfCFBP6992P_16450	COG1611	Belongs to the LOG family
XcfCFBP6992P_16465	COG2095	MarC family integral membrane protein
XcfCFBP6992P_16475	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XcfCFBP6992P_16510	COG1185	polyribonucleotide nucleotidyltransferase activity
XcfCFBP6992P_16515	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
XcfCFBP6992P_16520	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
XcfCFBP6992P_16525	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
XcfCFBP6992P_16530	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
XcfCFBP6992P_16535	COG0195	Participates in both transcription termination and antitermination
XcfCFBP6992P_16540	COG0779	Required for maturation of 30S ribosomal subunits
XcfCFBP6992P_16550	COG1007	ATP synthesis coupled electron transport
XcfCFBP6992P_16575	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XcfCFBP6992P_16580	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
XcfCFBP6992P_16590	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XcfCFBP6992P_16595	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
XcfCFBP6992P_16600	COG0649	NAD binding
XcfCFBP6992P_16605	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XcfCFBP6992P_16610	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XcfCFBP6992P_16615	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XcfCFBP6992P_16630	COG0149	triose-phosphate isomerase activity
XcfCFBP6992P_16635	COG4221	oxidoreductase activity
XcfCFBP6992P_16665	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XcfCFBP6992P_16670	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
XcfCFBP6992P_16675	COG0159	tryptophan synthase activity
XcfCFBP6992P_16685	COG0133	tryptophan synthase activity
XcfCFBP6992P_16695	COG0135	phosphoribosylanthranilate isomerase activity
XcfCFBP6992P_16700	COG0101	tRNA pseudouridine synthase activity
XcfCFBP6992P_16720	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XcfCFBP6992P_16725	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XcfCFBP6992P_16730	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
XcfCFBP6992P_16735	COG2890	protein-(glutamine-N5) methyltransferase activity
XcfCFBP6992P_16745	COG0688	phosphatidylethanolamine metabolic process
XcfCFBP6992P_16760	COG0433	COG0433 Predicted ATPase
XcfCFBP6992P_16765	COG0494	nUDIX hydrolase
XcfCFBP6992P_16780	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XcfCFBP6992P_16785	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XcfCFBP6992P_16805	COG0717	Belongs to the dCTP deaminase family
XcfCFBP6992P_16815	COG0489	protein tyrosine kinase activity
XcfCFBP6992P_16840	COG3590	peptidase
XcfCFBP6992P_16845	COG3590	peptidase
XcfCFBP6992P_16865	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XcfCFBP6992P_16870	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XcfCFBP6992P_16875	COG2311	Membrane
XcfCFBP6992P_16880	COG1047	Peptidyl-prolyl cis-trans
XcfCFBP6992P_16885	COG0791	NLP P60 protein
XcfCFBP6992P_16890	COG0791	NLP P60 protein
XcfCFBP6992P_16900	COG4106	trans-aconitate 2-methyltransferase activity
XcfCFBP6992P_16905	COG1301	dicarboxylic acid transport
XcfCFBP6992P_16910	COG1785	Belongs to the alkaline phosphatase family
XcfCFBP6992P_16920	COG0037	tRNA processing
XcfCFBP6992P_16925	COG1722	exodeoxyribonuclease VII activity
XcfCFBP6992P_16930	COG0142	geranyltranstransferase activity
XcfCFBP6992P_16935	COG4104	PAAR repeat-containing protein
XcfCFBP6992P_16945	COG0312	modulator of DNA gyrase
XcfCFBP6992P_16950	COG3028	Belongs to the UPF0307 family
XcfCFBP6992P_16955	COG0312	modulator of DNA gyrase
XcfCFBP6992P_16965	COG3164	Protein of unknown function
XcfCFBP6992P_16975	COG0424	maF-like protein
XcfCFBP6992P_16980	COG2968	Membrane
XcfCFBP6992P_16995	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
XcfCFBP6992P_17010	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
XcfCFBP6992P_17025	COG0495	leucyl-tRNA aminoacylation
XcfCFBP6992P_17035	COG3118	belongs to the thioredoxin family
XcfCFBP6992P_17070	COG2155	Conserved Protein
XcfCFBP6992P_17115	COG1132	(ABC) transporter
XcfCFBP6992P_17140	COG1538	Outer membrane efflux protein
XcfCFBP6992P_17145	COG0745	RESPONSE REGULATOR receiver
XcfCFBP6992P_17150	COG5002	protein histidine kinase activity
XcfCFBP6992P_17150	COG5000	phosphorelay sensor kinase activity
XcfCFBP6992P_17155	COG0475	glutathione-regulated potassium exporter activity
XcfCFBP6992P_17165	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XcfCFBP6992P_17190	COG1187	pseudouridine synthase activity
XcfCFBP6992P_17195	COG5002	protein histidine kinase activity
XcfCFBP6992P_17195	COG5001	Diguanylate cyclase
XcfCFBP6992P_17205	COG1595	DNA-templated transcription, initiation
XcfCFBP6992P_17310	COG0667	Aldo Keto reductase
XcfCFBP6992P_17315	COG2814	Major facilitator Superfamily
XcfCFBP6992P_17320	COG0583	DNA-binding transcription factor activity
XcfCFBP6992P_17330	COG2207	Transcriptional regulator
XcfCFBP6992P_17340	COG1309	transcriptional regulator
XcfCFBP6992P_17350	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcfCFBP6992P_17365	COG0735	belongs to the Fur family
XcfCFBP6992P_17370	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XcfCFBP6992P_17395	COG4452	Inner membrane protein CreD
XcfCFBP6992P_17410	COG0745	RESPONSE REGULATOR receiver
XcfCFBP6992P_17415	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
XcfCFBP6992P_17425	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
XcfCFBP6992P_17435	COG0643	Histidine kinase
XcfCFBP6992P_17435	COG2198	Histidine kinase
XcfCFBP6992P_17440	COG0840	transmembrane signaling receptor activity
XcfCFBP6992P_17445	COG0835	chemotaxis
XcfCFBP6992P_17455	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XcfCFBP6992P_17465	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XcfCFBP6992P_17470	COG3590	peptidase
XcfCFBP6992P_17480	COG0588	phosphoglycerate mutase activity
XcfCFBP6992P_17485	COG1515	deoxyribonuclease V activity
XcfCFBP6992P_17495	COG1741	Belongs to the pirin family
XcfCFBP6992P_17510	COG1741	Belongs to the pirin family
XcfCFBP6992P_17515	COG1966	Carbon starvation protein
XcfCFBP6992P_17520	COG2879	small protein
XcfCFBP6992P_17570	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
XcfCFBP6992P_17575	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XcfCFBP6992P_17580	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XcfCFBP6992P_17585	COG2080	2 iron, 2 sulfur cluster binding
XcfCFBP6992P_17590	COG0604	alcohol dehydrogenase
XcfCFBP6992P_17590	COG3321	synthase
XcfCFBP6992P_17590	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6992P_17595	COG5001	Diguanylate cyclase
XcfCFBP6992P_17595	COG4251	negative regulation of phosphorylation
XcfCFBP6992P_17595	COG3706	GGDEF domain
XcfCFBP6992P_17595	COG2203	Gaf domain
XcfCFBP6992P_17600	COG0629	single-stranded DNA binding
XcfCFBP6992P_17605	COG0142	geranyltranstransferase activity
XcfCFBP6992P_17620	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
XcfCFBP6992P_17635	COG0527	aspartate kinase activity
XcfCFBP6992P_17645	COG0384	phenazine biosynthesis protein PhzF
XcfCFBP6992P_17655	COG1764	response to oxidative stress
XcfCFBP6992P_17660	COG0540	Belongs to the ATCase OTCase family
XcfCFBP6992P_17665	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
XcfCFBP6992P_17670	COG1678	Uncharacterized ACR, COG1678
XcfCFBP6992P_17680	COG0519	Catalyzes the synthesis of GMP from XMP
XcfCFBP6992P_17710	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
XcfCFBP6992P_17725	COG0739	heme binding
XcfCFBP6992P_17745	COG0693	protein deglycase activity
XcfCFBP6992P_17755	COG1959	2 iron, 2 sulfur cluster binding
XcfCFBP6992P_17760	COG0719	Fe-S assembly protein
XcfCFBP6992P_17765	COG0396	ATPase activity
XcfCFBP6992P_17770	COG0719	Fe-S assembly protein
XcfCFBP6992P_17775	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XcfCFBP6992P_17785	COG2146	nitrite reductase [NAD(P)H] activity
XcfCFBP6992P_17795	COG3128	pkhd-type hydroxylase
XcfCFBP6992P_17820	COG1477	protein flavinylation
XcfCFBP6992P_17825	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XcfCFBP6992P_17835	COG1555	photosystem II stabilization
XcfCFBP6992P_17850	COG3178	'Phosphotransferase
XcfCFBP6992P_17855	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XcfCFBP6992P_17870	COG0628	permease
XcfCFBP6992P_17880	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
XcfCFBP6992P_17890	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
XcfCFBP6992P_17910	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
XcfCFBP6992P_17915	COG0271	Belongs to the BolA IbaG family
XcfCFBP6992P_17925	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
XcfCFBP6992P_17935	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
XcfCFBP6992P_17940	COG1137	ATPase activity
XcfCFBP6992P_17955	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
XcfCFBP6992P_17960	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
XcfCFBP6992P_17965	COG1660	Displays ATPase and GTPase activities
XcfCFBP6992P_17975	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XcfCFBP6992P_17980	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XcfCFBP6992P_17985	COG2239	Acts as a magnesium transporter
XcfCFBP6992P_17995	COG1294	oxidase, subunit
XcfCFBP6992P_18000	COG1271	oxidase subunit
XcfCFBP6992P_18010	COG1113	amino acid transport
XcfCFBP6992P_18040	COG2197	response regulator
XcfCFBP6992P_18045	COG0531	amino acid
XcfCFBP6992P_18155	COG2814	Major facilitator Superfamily
XcfCFBP6992P_18165	COG0754	glutathionylspermidine amidase activity
XcfCFBP6992P_18190	COG1842	Phage shock protein A
XcfCFBP6992P_18200	COG0259	pyridoxamine-phosphate oxidase activity
XcfCFBP6992P_18205	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
XcfCFBP6992P_18210	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
XcfCFBP6992P_18220	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
XcfCFBP6992P_18225	COG2814	Major facilitator Superfamily
XcfCFBP6992P_18250	COG2205	protein histidine kinase activity
XcfCFBP6992P_18250	COG2198	Histidine kinase
XcfCFBP6992P_18250	COG0784	Response regulator, receiver
XcfCFBP6992P_18255	COG2353	YceI-like domain
XcfCFBP6992P_18275	COG1760	l-serine dehydratase
XcfCFBP6992P_18290	COG0460	homoserine dehydrogenase
XcfCFBP6992P_18290	COG0527	aspartate kinase activity
XcfCFBP6992P_18295	COG0626	cystathionine gamma-synthase activity
XcfCFBP6992P_18300	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XcfCFBP6992P_18305	COG0739	heme binding
XcfCFBP6992P_18310	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
XcfCFBP6992P_18315	COG1272	protein, Hemolysin III
XcfCFBP6992P_18320	COG2982	Protein involved in outer membrane biogenesis
XcfCFBP6992P_18325	COG0516	GMP reductase activity
XcfCFBP6992P_18325	COG0517	IMP dehydrogenase activity
XcfCFBP6992P_18330	COG0463	Glycosyl transferase, family 2
XcfCFBP6992P_18335	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XcfCFBP6992P_18340	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
XcfCFBP6992P_18350	COG4771	TonB-dependent receptor
XcfCFBP6992P_18355	COG1309	transcriptional regulator
XcfCFBP6992P_18365	COG1960	acyl-CoA dehydrogenase activity
XcfCFBP6992P_18390	COG0509	glycine decarboxylation via glycine cleavage system
XcfCFBP6992P_18395	COG0404	The glycine cleavage system catalyzes the degradation of glycine
XcfCFBP6992P_18410	COG1742	UPF0060 membrane protein
XcfCFBP6992P_18415	COG3956	TIGRFAM MazG family protein
XcfCFBP6992P_18420	COG1218	3'(2'),5'-bisphosphate nucleotidase
XcfCFBP6992P_18425	COG0494	nUDIX hydrolase
XcfCFBP6992P_18435	COG1385	rRNA (uridine-N3-)-methyltransferase activity
XcfCFBP6992P_18440	COG0837	glucose binding
XcfCFBP6992P_18455	COG1388	LysM domain
XcfCFBP6992P_18455	COG3858	chitin binding
XcfCFBP6992P_18460	COG3525	Glycosyl hydrolase, family 20, catalytic domain
XcfCFBP6992P_18470	COG1472	Belongs to the glycosyl hydrolase 3 family
XcfCFBP6992P_18485	COG0531	amino acid
XcfCFBP6992P_18495	COG1486	melibiose metabolic process
XcfCFBP6992P_18505	COG3537	Alpha-1,2-mannosidase
XcfCFBP6992P_18545	COG3142	Participates in the control of copper homeostasis
XcfCFBP6992P_18550	COG1446	asparaginase
XcfCFBP6992P_18575	COG2198	Histidine kinase
XcfCFBP6992P_18575	COG0784	Response regulator, receiver
XcfCFBP6992P_18575	COG0643	Histidine kinase
XcfCFBP6992P_18580	COG0840	transmembrane signaling receptor activity
XcfCFBP6992P_18585	COG0835	chemotaxis
XcfCFBP6992P_18600	COG0189	ligase activity
XcfCFBP6992P_18610	COG1397	ADP-ribosylglycohydrolase
XcfCFBP6992P_18620	COG1199	ATP-dependent helicase activity
XcfCFBP6992P_18630	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XcfCFBP6992P_18635	COG1216	Glycosyl transferase, family 2
XcfCFBP6992P_18650	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XcfCFBP6992P_18660	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
XcfCFBP6992P_18665	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
XcfCFBP6992P_18670	COG0535	radical SAM domain protein
XcfCFBP6992P_18675	COG0535	radical SAM domain protein
XcfCFBP6992P_18690	COG0837	glucose binding
XcfCFBP6992P_18700	COG1643	Atp-dependent helicase
XcfCFBP6992P_18705	COG0783	Belongs to the Dps family
XcfCFBP6992P_18710	COG0514	ATP-dependent DNA helicase (RecQ)
XcfCFBP6992P_18745	COG0840	transmembrane signaling receptor activity
XcfCFBP6992P_18765	COG3920	Histidine kinase
XcfCFBP6992P_18770	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
XcfCFBP6992P_18780	COG0602	queuosine metabolic process
XcfCFBP6992P_18790	COG2885	chlorophyll binding
XcfCFBP6992P_18795	COG0823	Involved in the tonB-independent uptake of proteins
XcfCFBP6992P_18805	COG0848	biopolymer transport protein
XcfCFBP6992P_18815	COG0824	Thioesterase
XcfCFBP6992P_18820	COG2255	four-way junction helicase activity
XcfCFBP6992P_18830	COG3158	transport of potassium into the cell
XcfCFBP6992P_18835	COG0632	four-way junction helicase activity
XcfCFBP6992P_18840	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
XcfCFBP6992P_18845	COG0217	transcriptional regulatory protein
XcfCFBP6992P_18860	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
XcfCFBP6992P_18875	COG0477	Major facilitator Superfamily
XcfCFBP6992P_18915	COG0488	(ABC) transporter
XcfCFBP6992P_18955	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XcfCFBP6992P_18955	COG4651	solute:proton antiporter activity
XcfCFBP6992P_18965	COG4772	TonB-dependent receptor
XcfCFBP6992P_18975	COG4264	IucA IucC family
XcfCFBP6992P_18990	COG0019	diaminopimelate decarboxylase activity
XcfCFBP6992P_19015	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
XcfCFBP6992P_19025	COG1492	cobalamin metabolic process
XcfCFBP6992P_19035	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XcfCFBP6992P_19060	COG4206	TonB-dependent receptor
XcfCFBP6992P_19065	COG0542	response to heat
XcfCFBP6992P_19070	COG1116	anion transmembrane transporter activity
XcfCFBP6992P_19075	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XcfCFBP6992P_19080	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XcfCFBP6992P_19085	COG0667	Aldo Keto reductase
XcfCFBP6992P_19090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XcfCFBP6992P_19095	COG4771	TonB-dependent receptor
XcfCFBP6992P_19100	COG2827	Endonuclease containing a URI domain
XcfCFBP6992P_19140	COG1877	trehalose-phosphatase activity
XcfCFBP6992P_19145	COG3387	PFAM Glycoside hydrolase 15-related
XcfCFBP6992P_19165	COG0840	transmembrane signaling receptor activity
XcfCFBP6992P_19170	COG3011	Protein conserved in bacteria
XcfCFBP6992P_19185	COG0564	pseudouridine synthase activity
XcfCFBP6992P_19190	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XcfCFBP6992P_19200	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
XcfCFBP6992P_19200	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XcfCFBP6992P_19215	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
XcfCFBP6992P_19220	COG0045	succinate-CoA ligase (ADP-forming) activity
XcfCFBP6992P_19275	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
XcfCFBP6992P_19280	COG0237	dephospho-CoA kinase activity
XcfCFBP6992P_19335	COG0745	RESPONSE REGULATOR receiver
XcfCFBP6992P_19345	COG0189	ligase activity
XcfCFBP6992P_19390	COG2022	thiamine diphosphate biosynthetic process
XcfCFBP6992P_19395	COG0220	tRNA (guanine-N7-)-methyltransferase activity
XcfCFBP6992P_19400	COG0471	metal ion transport
XcfCFBP6992P_19400	COG3273	potassium ion transport
XcfCFBP6992P_19425	COG1970	mechanosensitive ion channel activity
XcfCFBP6992P_19435	COG1609	Transcriptional regulator
XcfCFBP6992P_19445	COG3250	beta-galactosidase activity
XcfCFBP6992P_19450	COG4948	Mandelate Racemase Muconate Lactonizing
XcfCFBP6992P_19460	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XcfCFBP6992P_19470	COG0308	aminopeptidase N
XcfCFBP6992P_19475	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcfCFBP6992P_19485	COG2895	sulfate adenylyltransferase (ATP) activity
XcfCFBP6992P_19485	COG0529	Catalyzes the synthesis of activated sulfate
XcfCFBP6992P_19490	COG0175	sulfate reduction
XcfCFBP6992P_19495	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XcfCFBP6992P_19500	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XcfCFBP6992P_19505	COG0175	sulfate reduction
XcfCFBP6992P_19525	COG2205	protein histidine kinase activity
XcfCFBP6992P_19525	COG2198	Histidine kinase
XcfCFBP6992P_19525	COG0784	Response regulator, receiver
XcfCFBP6992P_19545	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XcfCFBP6992P_19545	COG1648	precorrin-2 dehydrogenase activity
XcfCFBP6992P_19560	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
XcfCFBP6992P_19565	COG3588	fructose-bisphosphate aldolase
XcfCFBP6992P_19580	COG0469	pyruvate kinase activity
XcfCFBP6992P_19590	COG0126	phosphoglycerate kinase activity
XcfCFBP6992P_19615	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
XcfCFBP6992P_19625	COG3047	cAMP biosynthetic process
XcfCFBP6992P_19630	COG3047	cAMP biosynthetic process
XcfCFBP6992P_19640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XcfCFBP6992P_19640	COG3453	Protein conserved in bacteria
XcfCFBP6992P_19645	COG0725	ABC transporter, periplasmic molybdate-binding protein
XcfCFBP6992P_19650	COG4149	molybdate abc transporter
XcfCFBP6992P_19655	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
XcfCFBP6992P_19690	COG1376	ErfK ybiS ycfS ynhG family protein
XcfCFBP6992P_19695	COG0739	heme binding
XcfCFBP6992P_19700	COG4773	Receptor
XcfCFBP6992P_19710	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
XcfCFBP6992P_19715	COG1301	dicarboxylic acid transport
XcfCFBP6992P_19725	COG2304	oxidoreductase activity
XcfCFBP6992P_19745	COG0714	Associated with various cellular activities
XcfCFBP6992P_19775	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XcfCFBP6992P_19800	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
XcfCFBP6992P_19810	COG2721	sulfolactate sulfo-lyase activity
XcfCFBP6992P_19825	COG2271	Major facilitator Superfamily
XcfCFBP6992P_19840	COG0583	DNA-binding transcription factor activity
XcfCFBP6992P_19845	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XcfCFBP6992P_19860	COG1561	YicC-like family, N-terminal region
XcfCFBP6992P_19865	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
XcfCFBP6992P_19875	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
XcfCFBP6992P_19880	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XcfCFBP6992P_19895	COG0006	proline dipeptidase activity
XcfCFBP6992P_19905	COG0006	proline dipeptidase activity
XcfCFBP6992P_19910	COG3079	Belongs to the UPF0149 family
XcfCFBP6992P_19930	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
XcfCFBP6992P_19940	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
XcfCFBP6992P_19950	COG2912	Transglutaminase-like superfamily
XcfCFBP6992P_19955	COG1773	rubredoxin
XcfCFBP6992P_19960	COG0352	thiamine-phosphate diphosphorylase activity
XcfCFBP6992P_19975	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XcfCFBP6992P_19995	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XcfCFBP6992P_20025	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XcfCFBP6992P_20030	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XcfCFBP6992P_20035	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6992P_20045	COG0671	phosphoesterase, PA-phosphatase related
XcfCFBP6992P_20050	COG3781	membrane
XcfCFBP6992P_20060	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XcfCFBP6992P_20065	COG0563	adenylate kinase activity
XcfCFBP6992P_20080	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
XcfCFBP6992P_20090	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
XcfCFBP6992P_20110	COG3710	Transcriptional regulator
XcfCFBP6992P_20115	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
XcfCFBP6992P_20130	COG0840	transmembrane signaling receptor activity
XcfCFBP6992P_20135	COG0405	Gamma-glutamyltransferase
XcfCFBP6992P_20140	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
XcfCFBP6992P_20160	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
XcfCFBP6992P_20165	COG0473	3-isopropylmalate dehydrogenase activity
XcfCFBP6992P_20170	COG0066	3-isopropylmalate dehydratase activity
XcfCFBP6992P_20175	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
XcfCFBP6992P_20195	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XcfCFBP6992P_20200	COG1538	Outer membrane efflux protein
XcfCFBP6992P_20205	COG1519	Transferase
XcfCFBP6992P_20215	COG1560	Kdo2-lipid A biosynthetic process
XcfCFBP6992P_20240	COG0280	phosphate acetyltransferase
XcfCFBP6992P_20240	COG0281	malic enzyme
XcfCFBP6992P_20245	COG1301	dicarboxylic acid transport
XcfCFBP6992P_20270	COG0583	DNA-binding transcription factor activity
XcfCFBP6992P_20280	COG0667	Aldo Keto reductase
XcfCFBP6992P_20295	COG2197	response regulator
XcfCFBP6992P_20310	COG0642	Histidine kinase
XcfCFBP6992P_20330	COG2851	Citrate transporter
XcfCFBP6992P_20335	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6992P_20340	COG1609	Transcriptional regulator
XcfCFBP6992P_20345	COG2211	Major facilitator Superfamily
XcfCFBP6992P_20375	COG1162	GTPase activity
XcfCFBP6992P_20380	COG0436	Aminotransferase
XcfCFBP6992P_20395	COG0726	polysaccharide deacetylase
XcfCFBP6992P_20400	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XcfCFBP6992P_20415	COG3964	amidohydrolase
XcfCFBP6992P_20420	COG0402	S-adenosylhomocysteine deaminase activity
XcfCFBP6992P_20445	COG1307	EDD domain protein, DegV family
XcfCFBP6992P_20450	COG0242	peptide deformylase activity
XcfCFBP6992P_20480	COG0457	Tetratricopeptide repeat
XcfCFBP6992P_20485	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
XcfCFBP6992P_20490	COG1215	transferase activity, transferring glycosyl groups
XcfCFBP6992P_20495	COG1215	transferase activity, transferring glycosyl groups
XcfCFBP6992P_20510	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
XcfCFBP6992P_20565	COG2188	Transcriptional regulator
XcfCFBP6992P_20575	COG1450	Type ii and iii secretion system protein
XcfCFBP6992P_20590	COG3166	PFAM Fimbrial assembly family protein
XcfCFBP6992P_20595	COG3156	type II secretion system protein K
XcfCFBP6992P_20600	COG4795	General secretion pathway protein
XcfCFBP6992P_20605	COG2165	general secretion pathway protein
XcfCFBP6992P_20610	COG4970	Tfp pilus assembly protein FimT
XcfCFBP6992P_20615	COG2165	general secretion pathway protein
XcfCFBP6992P_20620	COG1459	type II secretion system
XcfCFBP6992P_20630	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XcfCFBP6992P_20635	COG1404	Belongs to the peptidase S8 family
XcfCFBP6992P_20640	COG5295	Hep Hag repeat protein
XcfCFBP6992P_20645	COG1404	Belongs to the peptidase S8 family
XcfCFBP6992P_20650	COG5295	Hep Hag repeat protein
XcfCFBP6992P_20655	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XcfCFBP6992P_20655	COG0047	phosphoribosylformylglycinamidine synthase activity
XcfCFBP6992P_20665	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XcfCFBP6992P_20680	COG4974	Belongs to the 'phage' integrase family
XcfCFBP6992P_20695	COG0795	lipopolysaccharide-transporting ATPase activity
XcfCFBP6992P_20705	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XcfCFBP6992P_20720	COG0525	valine-tRNA ligase activity
XcfCFBP6992P_20755	COG1183	phosphatidylcholine synthase activity
XcfCFBP6992P_20765	COG0442	prolyl-tRNA aminoacylation
XcfCFBP6992P_20780	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XcfCFBP6992P_20785	COG1127	ABC transporter
XcfCFBP6992P_20790	COG3218	ABC-type transport auxiliary lipoprotein component
XcfCFBP6992P_20790	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XcfCFBP6992P_20825	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XcfCFBP6992P_20830	COG0662	Cupin 2, conserved barrel domain protein
XcfCFBP6992P_20830	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
XcfCFBP6992P_20860	COG2086	electron transfer activity
XcfCFBP6992P_20875	COG2226	methyltransferase
XcfCFBP6992P_20880	COG3328	transposase activity
XcfCFBP6992P_20905	COG0463	Glycosyl transferase, family 2
XcfCFBP6992P_20920	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
XcfCFBP6992P_20945	COG0626	cystathionine gamma-synthase activity
XcfCFBP6992P_20975	COG0625	glutathione transferase activity
XcfCFBP6992P_20990	COG0513	Belongs to the DEAD box helicase family
XcfCFBP6992P_21000	COG4206	TonB-dependent receptor
XcfCFBP6992P_21010	COG0720	synthase
XcfCFBP6992P_21020	COG2015	COG2015, Alkyl sulfatase and related hydrolases
XcfCFBP6992P_21030	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
XcfCFBP6992P_21035	COG1956	GAF domain-containing protein
XcfCFBP6992P_21045	COG2819	hydrolase of the alpha beta superfamily
XcfCFBP6992P_21055	COG0546	phosphoglycolate phosphatase activity
XcfCFBP6992P_21060	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
XcfCFBP6992P_21065	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XcfCFBP6992P_21080	COG0339	signal peptide processing
XcfCFBP6992P_21095	COG2132	Multicopper oxidase
XcfCFBP6992P_21130	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XcfCFBP6992P_21135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcfCFBP6992P_21140	COG1136	(ABC) transporter
XcfCFBP6992P_21145	COG0577	efflux transmembrane transporter activity
XcfCFBP6992P_21165	COG4191	Histidine kinase
XcfCFBP6992P_21170	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
XcfCFBP6992P_21185	COG0355	proton-transporting ATP synthase activity, rotational mechanism
XcfCFBP6992P_21190	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
XcfCFBP6992P_21195	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
XcfCFBP6992P_21200	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
XcfCFBP6992P_21205	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
XcfCFBP6992P_21210	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
XcfCFBP6992P_21220	COG0356	it plays a direct role in the translocation of protons across the membrane
XcfCFBP6992P_21240	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XcfCFBP6992P_21250	COG0508	dehydrogenase complex catalyzes the overall conversion of
XcfCFBP6992P_21285	COG2011	ABC-type metal ion transport system permease component
XcfCFBP6992P_21290	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
XcfCFBP6992P_21295	COG0697	spore germination
XcfCFBP6992P_21300	COG1666	GTP binding
XcfCFBP6992P_21310	COG0784	Response regulator, receiver
XcfCFBP6992P_21310	COG2198	Histidine kinase
XcfCFBP6992P_21310	COG5002	protein histidine kinase activity
XcfCFBP6992P_21330	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XcfCFBP6992P_21335	COG1187	pseudouridine synthase activity
XcfCFBP6992P_21340	COG2813	Specifically methylates the guanine in position
XcfCFBP6992P_21360	COG2202	Pas domain
XcfCFBP6992P_21360	COG2205	protein histidine kinase activity
XcfCFBP6992P_21380	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
XcfCFBP6992P_21385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XcfCFBP6992P_21440	COG0842	Transport permease protein
XcfCFBP6992P_21445	COG1131	(ABC) transporter
XcfCFBP6992P_21450	COG0025	NhaP-type Na H and K H
XcfCFBP6992P_21460	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
XcfCFBP6992P_21465	COG1573	uracil-dna glycosylase
XcfCFBP6992P_21475	COG3384	dioxygenase
XcfCFBP6992P_21485	COG0583	DNA-binding transcription factor activity
XcfCFBP6992P_21495	COG0667	Aldo Keto reductase
XcfCFBP6992P_21510	COG3590	peptidase
XcfCFBP6992P_21525	COG0531	amino acid
XcfCFBP6992P_21540	COG2972	Histidine kinase
XcfCFBP6992P_21565	COG3685	Protein conserved in bacteria
XcfCFBP6992P_21570	COG3546	catalase activity
XcfCFBP6992P_21605	COG2204	response regulator
XcfCFBP6992P_21620	COG1271	oxidase subunit
XcfCFBP6992P_21625	COG1294	oxidase, subunit
XcfCFBP6992P_21640	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6992P_21645	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
XcfCFBP6992P_21665	COG1132	(ABC) transporter
XcfCFBP6992P_21680	COG1063	alcohol dehydrogenase
XcfCFBP6992P_21755	COG0251	oxidation-reduction process
XcfCFBP6992P_21770	COG0840	transmembrane signaling receptor activity
XcfCFBP6992P_21785	COG0583	DNA-binding transcription factor activity
XcfCFBP6992P_21790	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XcfCFBP6992P_21820	COG0659	secondary active sulfate transmembrane transporter activity
XcfCFBP6992P_21835	COG0024	Methionine aminopeptidase
XcfCFBP6992P_21855	COG1487	ribonuclease activity
XcfCFBP6992P_21865	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XcfCFBP6992P_21865	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
XcfCFBP6992P_21935	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XcfCFBP6992P_21940	COG1490	D-aminoacyl-tRNA deacylase activity
XcfCFBP6992P_21945	COG1560	Kdo2-lipid A biosynthetic process
XcfCFBP6992P_22000	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
XcfCFBP6992P_22000	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XcfCFBP6992P_22005	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
XcfCFBP6992P_22010	COG0242	peptide deformylase activity
XcfCFBP6992P_22015	COG1652	LysM domain
XcfCFBP6992P_22020	COG0758	DNA mediated transformation
XcfCFBP6992P_22040	COG1754	DNA topoisomerase type I activity
XcfCFBP6992P_22040	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XcfCFBP6992P_22045	COG0009	L-threonylcarbamoyladenylate synthase
XcfCFBP6992P_22060	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6992P_22075	COG0616	signal peptide processing
XcfCFBP6992P_22080	COG0534	Mate efflux family protein
XcfCFBP6992P_22100	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
XcfCFBP6992P_22105	COG0625	glutathione transferase activity
XcfCFBP6992P_22120	COG1252	NADH dehydrogenase
XcfCFBP6992P_22125	COG2860	membrane
XcfCFBP6992P_22130	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XcfCFBP6992P_22135	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
XcfCFBP6992P_22140	COG2201	protein-glutamate methylesterase activity
XcfCFBP6992P_22145	COG2177	Part of the ABC transporter FtsEX involved in
XcfCFBP6992P_22150	COG2884	Cell division ATP-binding protein ftsE
XcfCFBP6992P_22155	COG0513	Belongs to the DEAD box helicase family
XcfCFBP6992P_22160	COG3118	belongs to the thioredoxin family
XcfCFBP6992P_22165	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
XcfCFBP6992P_22170	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
XcfCFBP6992P_22175	COG0583	DNA-binding transcription factor activity
XcfCFBP6992P_22195	COG1652	LysM domain
XcfCFBP6992P_22200	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XcfCFBP6992P_22200	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XcfCFBP6992P_22205	COG1473	amidohydrolase
XcfCFBP6992P_22210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcfCFBP6992P_22215	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcfCFBP6992P_22235	COG5383	Protein conserved in bacteria
XcfCFBP6992P_22295	COG4948	Mandelate Racemase Muconate Lactonizing
XcfCFBP6992P_22305	COG0531	amino acid
XcfCFBP6992P_22320	COG4682	membrane
XcfCFBP6992P_22325	COG2133	pyrroloquinoline quinone binding
XcfCFBP6992P_22335	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
XcfCFBP6992P_22340	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
XcfCFBP6992P_22350	COG1610	YqeY-like protein
XcfCFBP6992P_22360	COG1295	ribonuclease BN
XcfCFBP6992P_22365	COG0358	DNA primase activity
XcfCFBP6992P_22380	COG0109	protoheme IX farnesyltransferase activity
XcfCFBP6992P_22410	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
XcfCFBP6992P_22420	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XcfCFBP6992P_22465	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
XcfCFBP6992P_22470	COG0739	heme binding
XcfCFBP6992P_22475	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
XcfCFBP6992P_22485	COG2223	nitrite transmembrane transporter activity
XcfCFBP6992P_22490	COG0708	Exodeoxyribonuclease III
XcfCFBP6992P_22495	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
XcfCFBP6992P_22505	COG1192	Involved in chromosome partitioning
XcfCFBP6992P_22510	COG1475	DNA binding
XcfCFBP6992P_22530	COG0463	Glycosyl transferase, family 2
XcfCFBP6992P_22550	COG0756	dUTP diphosphatase activity
XcfCFBP6992P_22555	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
XcfCFBP6992P_22560	COG2003	Belongs to the UPF0758 family
XcfCFBP6992P_22565	COG0018	arginyl-trna synthetase
XcfCFBP6992P_22580	COG4221	oxidoreductase activity
XcfCFBP6992P_22585	COG2755	lipolytic protein G-D-S-L family
XcfCFBP6992P_22585	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
XcfCFBP6992P_22600	COG1166	arginine decarboxylase activity
XcfCFBP6992P_22605	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
XcfCFBP6992P_22630	COG3291	Pkd domain containing protein
XcfCFBP6992P_22630	COG3525	Glycosyl hydrolase, family 20, catalytic domain
XcfCFBP6992P_22650	COG0606	chelatase, subunit chli
XcfCFBP6992P_22660	COG4943	cyclic-guanylate-specific phosphodiesterase activity
XcfCFBP6992P_22700	COG1690	Belongs to the RtcB family
XcfCFBP6992P_22735	COG1090	epimerase
XcfCFBP6992P_22745	COG0642	Histidine kinase
XcfCFBP6992P_22770	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XcfCFBP6992P_22795	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XcfCFBP6992P_22800	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XcfCFBP6992P_22830	COG2197	response regulator
XcfCFBP6992P_22835	COG4585	Histidine kinase
XcfCFBP6992P_22840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcfCFBP6992P_22845	COG1136	(ABC) transporter
XcfCFBP6992P_22870	COG0697	spore germination
XcfCFBP6992P_22890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XcfCFBP6992P_22895	COG0180	Tryptophanyl-tRNA synthetase
XcfCFBP6992P_22900	COG3237	CsbD-like
XcfCFBP6992P_22925	COG4962	Type ii secretion system protein e
XcfCFBP6992P_22950	COG3328	transposase activity
XcfCFBP6992P_23145	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XcfCFBP6992P_23150	COG4691	Plasmid stability protein
XcfCFBP6992P_23155	COG1487	ribonuclease activity
XcfCFBP6992P_23220	COG3846	protein secretion by the type IV secretion system
XcfCFBP6992P_23600	COG3321	synthase
XcfCFBP6992P_23600	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6992P_23600	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XcfCFBP6992P_23600	COG4221	oxidoreductase activity
XcfCFBP6992P_23600	COG3321	synthase
XcfCFBP6992P_23600	COG1028	Short-chain dehydrogenase reductase Sdr
XcfCFBP6992P_23600	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XcfCFBP6992P_23600	COG4221	oxidoreductase activity
XcfCFBP6992P_23825	COG3451	type IV secretory pathway VirB4