locus-tag	class	description
CAI14_00005	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CAI14_00010	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
CAI14_00015	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
CAI14_00020	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
CAI14_00025	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
CAI14_00040	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
CAI14_00045	ENOG4105BZU	Histidine kinase
CAI14_00060	ENOG4107RBB	ABC transporter, permease
CAI14_00065	ENOG4107RBB	ABC transporter, permease
CAI14_00070	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CAI14_00075	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
CAI14_00080	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
CAI14_00120	ENOG4105E3B	Multicopper oxidase
CAI14_00135	ENOG4105DGW	oligopeptidase A
CAI14_00150	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
CAI14_00155	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
CAI14_00160	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
CAI14_00165	ENOG4107RNH	Outer membrane receptor FepA
CAI14_00170	ENOG4105NIV	Esterase
CAI14_00190	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
CAI14_00200	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
CAI14_00210	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
CAI14_00220	ENOG4105C1J	atp-dependent rna helicase
CAI14_00235	ENOG4108RXX	maleylacetoacetate isomerase
CAI14_00240	ENOG4105CZX	twitching motility protein
CAI14_00265	ENOG4105C28	cystathionine
CAI14_00275	ENOG4105EY8	ABC transporter
CAI14_00320	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
CAI14_00335	ENOG4105IQ5	FAD linked oxidase domain protein
CAI14_00350	ENOG4105C10	Electron transfer flavoprotein
CAI14_00355	ENOG4105BZJ	Electron transfer flavoprotein
CAI14_00370	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
CAI14_00375	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
CAI14_00385	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
CAI14_00390	ENOG4107QKV	phosphomannomutase
CAI14_00410	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
CAI14_00425	ENOG4108SNX	Mammalian cell entry related domain protein
CAI14_00430	ENOG4105DHJ	ABC, transporter
CAI14_00445	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
CAI14_00450	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
CAI14_00460	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
CAI14_00480	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
CAI14_00485	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
CAI14_00500	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
CAI14_00515	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
CAI14_00525	ENOG4108K5H	permease YjgP YjgQ family protein
CAI14_00540	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CAI14_00550	ENOG4105T95	Thiol disulfide interChange protein
CAI14_00560	ENOG4108ETH	Formylglycinamide ribotide synthetase
CAI14_00570	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
CAI14_00575	ENOG4105EUR	Domain-Containing protein
CAI14_00580	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
CAI14_00585	ENOG4107QHF	type ii secretion system protein e
CAI14_00595	ENOG4105D7Q	type ii secretion system
CAI14_00605	ENOG4105WMT	general secretion pathway protein h
CAI14_00615	ENOG41069G9	General secretion pathway protein J
CAI14_00620	ENOG4105UV2	general secretion pathway protein K
CAI14_00625	ENOG41090VX	general secretion pathway protein L
CAI14_00630	ENOG410678M	general secretion pathway protein M
CAI14_00640	ENOG4105GVR	general secretion pathway protein D
CAI14_00655	ENOG4106S9K	Transcriptional regulator
CAI14_00720	ENOG4107RH7	Nicotinate phosphoribosyltransferase
CAI14_00735	ENOG4107QZ7	Cellulose synthase catalytic subunit
CAI14_00740	ENOG4107EEX	Cellulose synthase regulator protein
CAI14_00745	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
CAI14_00750	ENOG4105EJG	cellulose synthase
CAI14_00780	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
CAI14_00785	ENOG4108RMV	DegV Family
CAI14_00820	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
CAI14_00825	ENOG41069H0	dihydroorotase EC 3.5.2.3
CAI14_00875	ENOG4105CHM	Aminotransferase
CAI14_00880	ENOG4108JJA	ABC, transporter
CAI14_00885	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
CAI14_00895	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
CAI14_00900	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
CAI14_00905	ENOG4105D7Q	type ii secretion system
CAI14_00920	ENOG4107QHF	type ii secretion system protein e
CAI14_00930	ENOG4107QHF	type ii secretion system protein e
CAI14_00940	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CAI14_00945	ENOG4107TUY	Histidine kinase
CAI14_00950	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
CAI14_00955	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
CAI14_00965	ENOG4105C4K	Nad synthetase
CAI14_00975	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CAI14_00980	ENOG4105C34	Pseudouridine synthase
CAI14_00995	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
CAI14_01000	ENOG4105C8Q	Methyl-accepting chemotaxis
CAI14_01010	ENOG4105DZG	Dehydrogenase
CAI14_01015	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
CAI14_01020	ENOG4105BZP	glycoside hydrolase 15-related
CAI14_01025	ENOG4108K4C	ec 3.1.3.12
CAI14_01035	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
CAI14_01070	ENOG41082IR	Excinuclease ABC C subunit domain protein
CAI14_01080	ENOG4107ZSV	Receptor
CAI14_01090	ENOG4105CPC	Aldo Keto reductase
CAI14_01095	ENOG4105GVF	(ABC) transporter
CAI14_01100	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
CAI14_01105	ENOG4105E2Y	ABC, transporter
CAI14_01110	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CAI14_01115	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
CAI14_01130	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
CAI14_01140	ENOG4105EFT	decarboxylase
CAI14_01145	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
CAI14_01150	ENOG4108YZT	Adenosylcobinamide kinase
CAI14_01155	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
CAI14_01185	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
CAI14_01210	ENOG4105GAV	receptor
CAI14_01235	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
CAI14_01250	ENOG4107RNH	Outer membrane receptor FepA
CAI14_01270	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
CAI14_01275	ENOG4105C5H	ABC transporter
CAI14_01285	ENOG4105ETT	transcriptional Regulator, LysR family
CAI14_01305	ENOG4105HSS	phospholipase C
CAI14_01315	ENOG4108ISG	Major Facilitator
CAI14_01330	ENOG4105C9M	aspartyl-trna synthetase
CAI14_01345	ENOG4105CDY	transcriptional regulatory protein
CAI14_01350	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
CAI14_01355	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
CAI14_01360	ENOG4105DFH	Transport of potassium into the cell (By similarity)
CAI14_01370	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
CAI14_01375	ENOG4107YD3	Thioesterase
CAI14_01380	ENOG4105E02	MotA TolQ exbB proton channel
CAI14_01395	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
CAI14_01400	ENOG4105KCK	Peptidoglycan-associated lipoprotein
CAI14_01410	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
CAI14_01420	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
CAI14_01425	ENOG410903D	sensor protein
CAI14_01445	ENOG4105C8Q	Methyl-accepting chemotaxis
CAI14_01480	ENOG4105C9U	ATP-dependent DNA helicase RecQ
CAI14_01495	ENOG4105CQ7	ATP-dependent helicase
CAI14_01525	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
CAI14_01530	ENOG4105Z85	coenzyme PQQ synthesis
CAI14_01535	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
CAI14_01540	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
CAI14_01545	ENOG410698T	Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide (By similarity)
CAI14_01550	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
CAI14_01575	ENOG4105BZ4	penicillin-binding protein
CAI14_01585	ENOG4105DVT	helicase
CAI14_01590	ENOG41072GX	Peptidase M22 Glycoprotease
CAI14_01595	ENOG41065RQ	ADP-ribosylation crystallin J1
CAI14_01605	ENOG4105D7Z	glutathione synthase
CAI14_01610	ENOG4108UNF	response regulator
CAI14_01615	ENOG4105M3Z	response regulator
CAI14_01625	ENOG4105C8Q	Methyl-accepting chemotaxis
CAI14_01645	ENOG4105D9U	N-acetyltransferase
CAI14_01665	ENOG4106N3A	copper homeostasis protein cutc
CAI14_01705	ENOG4105CWX	Alpha-1,2-mannosidase
CAI14_01735	ENOG4108JJA	ABC, transporter
CAI14_01755	ENOG4105VRS	hydrolase family 18
CAI14_01770	ENOG4105CHC	glucokinase (EC 2.7.1.2)
CAI14_01775	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
CAI14_01785	ENOG4107RK2	ADP-ribose diphosphatase NudE
CAI14_01790	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
CAI14_01795	ENOG4105DXN	mazG family
CAI14_01800	ENOG4105KK4	UPF0060 membrane protein
CAI14_01825	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
CAI14_01830	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
CAI14_01855	ENOG4107QPN	acyl-Coa dehydrogenase
CAI14_01865	ENOG4108IG5	Transcriptional regulator
CAI14_01880	ENOG4105D05	Receptor
CAI14_01890	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
CAI14_01895	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
CAI14_01905	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
CAI14_01910	ENOG41066T0	asmA family
CAI14_01915	ENOG4108UT2	hemolysin iii
CAI14_01920	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
CAI14_01925	ENOG4105DR5	peptidase
CAI14_01930	ENOG4106TYC	homoserine o-acetyltransferase (EC 2.3.1.31)
CAI14_01935	ENOG4105C28	cystathionine
CAI14_01940	ENOG4105CFH	Aspartokinase
CAI14_01955	ENOG4105EJQ	L-serine dehydratase
CAI14_01975	ENOG4108YYC	ycei family
CAI14_01980	ENOG4105BZU	Histidine kinase
CAI14_01990	ENOG4105BZU	Histidine kinase
CAI14_01995	ENOG4105BZU	Histidine kinase
CAI14_02000	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
CAI14_02005	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
CAI14_02015	ENOG4105D49	3-dehydroquinate synthase
CAI14_02020	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
CAI14_02025	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
CAI14_02035	ENOG4108P9J	Phage shock protein A
CAI14_02060	ENOG4106032	Glutathionylspermidine synthase
CAI14_02075	ENOG4108Z4X	TRANSCRIPTIONal
CAI14_02135	ENOG4107XDQ	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
CAI14_02145	ENOG4108MHS	Lysyl endopeptidase
CAI14_02165	ENOG4105CUB	amino acid
CAI14_02190	ENOG4108NFF	pectate lyase
CAI14_02200	ENOG4105C85	amino acid
CAI14_02220	ENOG4105C4M	(Ubiquinol oxidase) subunit I
CAI14_02225	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
CAI14_02235	ENOG4107UWA	esterase
CAI14_02240	ENOG4105CJW	magnesium transporter
CAI14_02250	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
CAI14_02255	ENOG41080Z8	PHOSPHOCARRIER protein
CAI14_02265	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
CAI14_02270	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
CAI14_02275	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
CAI14_02280	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
CAI14_02285	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CAI14_02290	ENOG4108IUZ	ABC transporter
CAI14_02295	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
CAI14_02305	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
CAI14_02310	ENOG4105C2X	Arabinose 5-phosphate isomerase
CAI14_02320	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
CAI14_02340	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
CAI14_02350	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
CAI14_02360	ENOG4105C02	permease
CAI14_02370	ENOG4108S0S	Nucleotidyl transferase
CAI14_02375	ENOG4105EHM	Aminoglycoside phosphotransferase
CAI14_02390	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
CAI14_02405	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
CAI14_02410	ENOG4105CJ2	(LipO)protein
CAI14_02435	ENOG4107E2E	PKHD-type hydroxylase
CAI14_02440	ENOG4108IU3	tonb-dependent siderophore receptor
CAI14_02445	ENOG4105VQD	rieske 2fe-2S domain-containing protein
CAI14_02455	ENOG4105C9B	Cysteine desulfurase
CAI14_02460	ENOG4105JRK	feS assembly protein SufD
CAI14_02465	ENOG4105C3K	feS assembly ATPase SufC
CAI14_02485	ENOG4108Z0Z	intracellular protease Pfpi family
CAI14_02505	ENOG4105FAA	peptidase M23
CAI14_02515	ENOG4105II7	pyrroline-5-carboxylate reductase
CAI14_02520	ENOG4105DFA	alanine racemase domain protein
CAI14_02525	ENOG4105CZX	twitching motility protein
CAI14_02530	ENOG4105CZX	twitching motility protein
CAI14_02535	ENOG4108E16	pectate lyase
CAI14_02545	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
CAI14_02555	ENOG4108UJU	UPF0301 protein
CAI14_02560	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
CAI14_02565	ENOG4105CXT	aspartate transcarbamylase
CAI14_02570	ENOG4108Z9K	Osmotically inducible protein
CAI14_02585	ENOG4105JAB	phenazine biosynthesis protein, phzf family
CAI14_02590	ENOG4105CFH	Aspartokinase
CAI14_02605	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
CAI14_02620	ENOG4105EAH	synthase
CAI14_02625	ENOG4108UUM	single-stranded DNA-binding protein
CAI14_02640	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
CAI14_02645	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
CAI14_02650	ENOG4105C7W	Xanthine dehydrogenase
CAI14_02655	ENOG4107XAN	XdhC and CoxI family
CAI14_02705	ENOG4105VCD	cytoplasmic protein
CAI14_02710	ENOG4105D22	carbon starvation protein
CAI14_02715	ENOG4105EUB	pirin domain protein
CAI14_02740	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
CAI14_02745	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
CAI14_02780	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
CAI14_02785	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
CAI14_02800	ENOG4107SM7	Transcriptional regulator
CAI14_02805	ENOG4107T8P	acyl-Coa dehydrogenase
CAI14_02810	ENOG4105D7T	ABC transporter
CAI14_02815	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
CAI14_02825	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
CAI14_02830	ENOG4108UZX	fmn reductase
CAI14_02855	ENOG4105DEF	Extracellular solute-binding protein, family 5
CAI14_02865	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CAI14_02875	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
CAI14_02880	ENOG4105NWN	ApaG protein
CAI14_02885	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
CAI14_02890	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
CAI14_02895	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
CAI14_02900	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
CAI14_02910	ENOG4108WBT	adenosyltransferase
CAI14_02925	ENOG4105D0A	hydroxylase
CAI14_02930	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
CAI14_02965	ENOG4105DDW	LysR family Transcriptional regulator
CAI14_02970	ENOG4105CEY	Amp-dependent synthetase and ligase
CAI14_02980	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
CAI14_03015	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
CAI14_03035	ENOG4105DXC	membrane
CAI14_03045	ENOG4105CX6	glutaminyL-tRNA synthetase
CAI14_03065	ENOG4105BZU	Histidine kinase
CAI14_03080	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
CAI14_03090	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
CAI14_03095	ENOG4105NXH	GreA GreB family elongation factor
CAI14_03105	ENOG4105C5Q	Transcriptional regulator
CAI14_03120	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
CAI14_03140	ENOG4105C2M	dna polymerase I
CAI14_03170	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
CAI14_03190	ENOG4105W8H	transhydrogenase (subunit alpha
CAI14_03195	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
CAI14_03210	ENOG4105CM2	brancheD-chain amino acid aminotransferase
CAI14_03220	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
CAI14_03230	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
CAI14_03235	ENOG4108Z66	YbaK ebsC protein
CAI14_03255	ENOG4105CS1	NAD(P)H quinone oxidoreductase
CAI14_03260	ENOG4107S2Z	UPF0761 membrane protein
CAI14_03280	ENOG4105CSR	polyphosphate kinase 2
CAI14_03300	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
CAI14_03305	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
CAI14_03310	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
CAI14_03315	ENOG4105QVB	outer membrane lipoprotein LolB
CAI14_03320	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
CAI14_03330	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
CAI14_03335	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
CAI14_03340	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
CAI14_03345	ENOG4105C3G	gtp-binding protein
CAI14_03365	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
CAI14_03375	ENOG4105PM1	preprotein translocase subunit SecE
CAI14_03380	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
CAI14_03385	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
CAI14_03390	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
CAI14_03395	ENOG4108VZM	50s ribosomal protein L10
CAI14_03400	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
CAI14_03405	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CAI14_03410	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CAI14_03420	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
CAI14_03425	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
CAI14_03430	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
CAI14_03435	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
CAI14_03440	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
CAI14_03445	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
CAI14_03455	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CAI14_03460	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
CAI14_03470	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
CAI14_03495	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
CAI14_03500	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CAI14_03510	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
CAI14_03515	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
CAI14_03520	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
CAI14_03535	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
CAI14_03540	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
CAI14_03570	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
CAI14_03590	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
CAI14_03600	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
CAI14_03610	ENOG4105CI3	gtp-binding protein typa
CAI14_03615	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
CAI14_03620	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
CAI14_03630	ENOG4108K3A	Glutathione S-transferase
CAI14_03650	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
CAI14_03665	ENOG4105CDV	Ompa motb domain protein
CAI14_03675	ENOG4108R99	pseudouridine synthase
CAI14_03685	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
CAI14_03690	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
CAI14_03695	ENOG4108I5D	sulfate abc transporter
CAI14_03705	ENOG4108IJ6	ABC transporter
CAI14_03715	ENOG4105CPQ	Dehydrogenase
CAI14_03750	ENOG4105CVJ	phosphoglycerate mutase
CAI14_03760	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
CAI14_03775	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
CAI14_03780	ENOG4105ED9	Protein of unknown function (DUF455)
CAI14_03800	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
CAI14_03805	ENOG4105EYK	Phosphatidylglycerophosphatase B
CAI14_03810	ENOG4105BZF	Glycosyl transferase (Group 1
CAI14_03815	ENOG4105C9X	ppx gppa phosphatase
CAI14_03820	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
CAI14_03825	ENOG4105BZU	Histidine kinase
CAI14_03830	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CAI14_03835	ENOG4105ERG	peptidase m48, ste24p
CAI14_03840	ENOG4105VW4	glutaredoxin 3
CAI14_03850	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
CAI14_03880	ENOG4105BZU	Histidine kinase
CAI14_03890	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
CAI14_03900	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
CAI14_03925	ENOG4105EIN	peptidylprolyl cis-trans isomerase
CAI14_03930	ENOG41068JE	domain protein
CAI14_03935	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
CAI14_03945	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CAI14_03950	ENOG4107RZZ	dna polymerase iii epsilon subunit
CAI14_03955	ENOG4108ZF3	Phosphatase
CAI14_03970	ENOG4105DKP	glycosyl transferase, family 9
CAI14_03975	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
CAI14_03980	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
CAI14_03985	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
CAI14_03990	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
CAI14_03995	ENOG4105M00	molybdopterin converting factor, subunit 1
CAI14_04000	ENOG4108ZAF	Molybdopterin
CAI14_04015	ENOG4107QMP	dna polymerase iii subunits gamma and tau
CAI14_04020	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
CAI14_04025	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
CAI14_04030	ENOG4105K59	histidine triad (HIT) protein
CAI14_04040	ENOG4105F8C	transglutaminase domain-containing protein
CAI14_04050	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
CAI14_04080	ENOG4108UHJ	MAF-like protein
CAI14_04085	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
CAI14_04090	ENOG4105VGS	50s ribosomal protein l32
CAI14_04095	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
CAI14_04105	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
CAI14_04110	ENOG4105CHR	reductase
CAI14_04120	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
CAI14_04130	ENOG4105HHA	aminodeoxychorismate lyase
CAI14_04135	ENOG4107QRG	dna polymerase iii
CAI14_04155	ENOG4108JU7	Transcriptional regulator
CAI14_04160	ENOG4105CR4	methylisocitrate lyase
CAI14_04165	ENOG4105BZN	citrate synthase
CAI14_04170	ENOG4108I0Z	Aconitate hydratase
CAI14_04175	ENOG4105YAJ	CopG Arc MetJ
CAI14_04190	ENOG4105C7F	AcnD-accessory protein PrpF
CAI14_04210	ENOG4105DN3	alpha-2-macroglobulin domain protein
CAI14_04230	ENOG4108JQB	penicillin-binding protein 1C
CAI14_04255	ENOG4105M3Z	response regulator
CAI14_04260	ENOG4107QJR	hflk protein
CAI14_04265	ENOG4105EPW	hflc protein
CAI14_04275	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
CAI14_04280	ENOG4105CD8	aminopeptidase N
CAI14_04285	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
CAI14_04290	ENOG4108XFH	Transcriptional regulator
CAI14_04320	ENOG4107XZC	Restriction modification system DNA (Specificity
CAI14_04345	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
CAI14_04385	ENOG4107Z4K	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
CAI14_04395	ENOG4105BZP	glycoside hydrolase 15-related
CAI14_04400	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
CAI14_04410	ENOG4105CWX	Alpha-1,2-mannosidase
CAI14_04415	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
CAI14_04425	ENOG4105C3M	thioredoxin reductase
CAI14_04485	ENOG4106AXJ	AraC family transcriptional regulator
CAI14_04515	ENOG4105CV8	reductase
CAI14_04520	ENOG4105EBR	Carboxylesterase
CAI14_04525	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CAI14_04530	ENOG4105C2C	drug resistance transporter, Bcr CflA
CAI14_04545	ENOG4105DIJ	Phosphoethanolamine transferase
CAI14_04560	ENOG4105ETX	regulatoR
CAI14_04565	ENOG4105DHQ	Histidine kinase
CAI14_04580	ENOG4107QMS	site-determining protein
CAI14_04585	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
CAI14_04600	ENOG4105BZU	Histidine kinase
CAI14_04605	ENOG4105WH1	Two component transcriptional regulator luxr family
CAI14_04650	ENOG4107SPG	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
CAI14_04660	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
CAI14_04710	ENOG4108TGP	Thioesterase superfamily protein
CAI14_04715	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
CAI14_04720	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
CAI14_04725	ENOG4105K46	50S ribosomal protein l27
CAI14_04730	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CAI14_04740	ENOG4105CJR	Integral membrane protein (MviN
CAI14_04745	ENOG4105DTN	riboflavin biosynthesis protein ribF
CAI14_04750	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
CAI14_04755	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
CAI14_04760	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
CAI14_04770	ENOG4105E2S	oxidase) subunit II
CAI14_04775	ENOG4105BZ9	Cytochrome C oxidase, subunit I
CAI14_04780	ENOG4105CCU	oxidase (Subunit III)
CAI14_04785	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
CAI14_04795	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
CAI14_04800	ENOG4105KAF	membrAne
CAI14_04815	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
CAI14_04825	ENOG4107MMM	Anti-sigma-factor antagonist
CAI14_04830	ENOG4105FUA	antagonist
CAI14_04835	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
CAI14_04845	ENOG4105BZU	Histidine kinase
CAI14_04870	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
CAI14_04875	ENOG4105C08	Histidine kinase
CAI14_04880	ENOG4107Z5C	methylesterase
CAI14_04885	ENOG4105BZU	Histidine kinase
CAI14_04890	ENOG4105BZU	Histidine kinase
CAI14_04920	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
CAI14_04925	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
CAI14_04930	ENOG4105CRE	cytochrome C
CAI14_04935	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CAI14_04940	ENOG4107QWG	2-Nitropropane dioxygenase
CAI14_04950	ENOG4105K5M	30s ribosomal protein S16
CAI14_04955	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
CAI14_04960	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
CAI14_04965	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
CAI14_04970	ENOG4107QJQ	Mate efflux family protein
CAI14_04985	ENOG4105VEJ	Heat shock protein
CAI14_04990	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
CAI14_05000	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
CAI14_05035	ENOG4105DHP	deoxycytidine triphosphate deaminase
CAI14_05240	ENOG4105NVB	glycoside hydrolase, family 19
CAI14_05285	ENOG4105ED4	portal protein
CAI14_05315	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
CAI14_05330	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
CAI14_05335	ENOG4108RRZ	Transcription elongation factor GreB
CAI14_05355	ENOG4107VIJ	nudix hydrolase
CAI14_05360	ENOG4105D7A	ATP-binding protein
CAI14_05375	ENOG4105DJ4	phosphatidylserine decarboxylase
CAI14_05385	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
CAI14_05390	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
CAI14_05395	ENOG4105C5I	Dehydrogenase
CAI14_05400	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
CAI14_05420	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
CAI14_05425	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
CAI14_05435	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
CAI14_05445	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
CAI14_05450	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
CAI14_05455	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
CAI14_05470	ENOG4105BZU	Histidine kinase
CAI14_05485	ENOG4107FW0	short-chain dehydrogenase reductase
CAI14_05490	ENOG4105CP7	Triose-phosphate isomerase
CAI14_05505	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CAI14_05510	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CAI14_05515	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CAI14_05520	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CAI14_05525	ENOG4105GKE	subunit e
CAI14_05530	ENOG4107QIZ	NADH dehydrogenase
CAI14_05535	ENOG4107R0R	NADH dehydrogenase subunit g
CAI14_05540	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
CAI14_05545	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CAI14_05560	ENOG4105D65	subunit l
CAI14_05565	ENOG4105C8S	subunit m
CAI14_05570	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CAI14_05580	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
CAI14_05585	ENOG4105CHV	Transcription elongation factor NusA
CAI14_05590	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
CAI14_05595	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
CAI14_05600	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
CAI14_05610	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
CAI14_05620	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
CAI14_05630	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
CAI14_05635	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
CAI14_05640	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
CAI14_05645	ENOG4105M2J	Glutaredoxin
CAI14_05655	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
CAI14_05665	ENOG4108KPZ	tonB-dependent Receptor
CAI14_05670	ENOG4105EWT	decarboxylase family
CAI14_05725	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
CAI14_05765	ENOG4105CMA	conjugation trbi family protein
CAI14_05810	ENOG4105ETE	Transcriptional regulator (LacI family
CAI14_05815	ENOG4105C22	threonyL-tRNA synthetase
CAI14_05820	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
CAI14_05835	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
CAI14_05840	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
CAI14_05850	ENOG4105WJX	transcriptional regulator MERR family
CAI14_05870	ENOG4105D3Q	Sugar transferase
CAI14_05895	ENOG4107Y2G	Glycosyl transferase (Group 1
CAI14_05905	ENOG4108NQK	Catalyzes the transfer of a glucuronic acid (GlcA) residue from UDP-glucuronate to mannose-alpha-1,3-glucose-beta- 1,4-glucose-P-P-polyisoprenyl to form the lipid-linked tetrasaccharide GlcA-Man-Glc(2)-PP-Pol, with a glucuronic acid- beta-mannose linkage. Is involved in the biosynthesis of the exopolysaccharide xanthan, since it catalyzes the fourth glycosylation step in the assembly of the pentasaccharide-P-P- polyisoprenyl repeating unit of xanthan. Is unable to use the trisaccharide acceptor freed from the pyrophosphate lipid moiety. Does not show specificity for the lipidic portion of the acceptor. Shows diminished activity when tested with 6-O-acetyl-mannose- alpha-1,3-glucose-beta-1,4-glucose-P-P-polyisoprenyl, a
CAI14_05930	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
CAI14_05935	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
CAI14_05940	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
CAI14_05960	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
CAI14_05970	ENOG4105CSU	acyl-Coa dehydrogenase
CAI14_05985	ENOG4105QNF	Outer membrane lipoprotein
CAI14_06030	ENOG4105CQZ	Histidine kinase
CAI14_06035	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
CAI14_06040	ENOG4105CEN	a g-specific adenine glycosylase
CAI14_06050	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CAI14_06060	ENOG4105CTU	Proline racemase
CAI14_06065	ENOG41080HI	glycine oxidase
CAI14_06080	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
CAI14_06090	ENOG4105DC7	peptidase M24
CAI14_06105	ENOG4107QTZ	amino acid
CAI14_06250	ENOG4107BJW	polysaccharide deacetylase
CAI14_06345	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
CAI14_06350	ENOG4105CUT	histidyl-tRNA synthetase
CAI14_06360	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
CAI14_06365	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
CAI14_06370	ENOG4105CIH	Imidazole acetol-phosphate transaminase
CAI14_06375	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
CAI14_06380	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
CAI14_06385	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
CAI14_06390	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
CAI14_06395	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
CAI14_06410	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
CAI14_06415	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
CAI14_06420	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
CAI14_06425	ENOG4105CUB	amino acid
CAI14_06430	ENOG4105CUB	amino acid
CAI14_06440	ENOG4108JQ1	Dehydrogenase
CAI14_06445	ENOG4105CQB	FAD linked oxidase domain protein
CAI14_06465	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
CAI14_06475	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
CAI14_06495	ENOG4105CE1	Ferrous iron transport protein b
CAI14_06515	ENOG4108RPX	mosc domain containing protein
CAI14_06520	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
CAI14_06525	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
CAI14_06535	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
CAI14_06540	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
CAI14_06550	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
CAI14_06600	ENOG4105DY9	regulatoR
CAI14_06610	ENOG4105CRK	lysyL-tRNA synthetase
CAI14_06615	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CAI14_06620	ENOG4105BZU	Histidine kinase
CAI14_06625	ENOG4105E39	Enoyl-CoA hydratase
CAI14_06660	ENOG4105CEY	Amp-dependent synthetase and ligase
CAI14_06670	ENOG4107QM5	aconitate hydratase
CAI14_06685	ENOG4107QIJ	Aconitate hydratase 2
CAI14_06690	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
CAI14_06695	ENOG4105BZU	Histidine kinase
CAI14_06700	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
CAI14_06705	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
CAI14_06710	ENOG4105BZU	Histidine kinase
CAI14_06715	ENOG4105C8Q	Methyl-accepting chemotaxis
CAI14_06725	ENOG4108V3W	Chemotaxis protein, CheW
CAI14_06740	ENOG4105C8Q	Methyl-accepting chemotaxis
CAI14_06745	ENOG4105C8Q	Methyl-accepting chemotaxis
CAI14_06750	ENOG4105C8Q	Methyl-accepting chemotaxis
CAI14_06755	ENOG4105C8Q	Methyl-accepting chemotaxis
CAI14_06760	ENOG4105C8Q	Methyl-accepting chemotaxis
CAI14_06770	ENOG4105C8Q	Methyl-accepting chemotaxis
CAI14_06775	ENOG4105C8Q	Methyl-accepting chemotaxis
CAI14_06785	ENOG4105C8Q	Methyl-accepting chemotaxis
CAI14_06790	ENOG4105C8Q	Methyl-accepting chemotaxis
CAI14_06805	ENOG4105C8Q	Methyl-accepting chemotaxis
CAI14_06820	ENOG4105C8Q	Methyl-accepting chemotaxis
CAI14_06825	ENOG4105CBS	Chea signal transduction histidine kinase
CAI14_06830	ENOG4108VYJ	response regulator receiver protein
CAI14_06840	ENOG4108V3W	Chemotaxis protein, CheW
CAI14_06850	ENOG4105ER2	Ompa motb domain protein
CAI14_06855	ENOG4105E14	MotA TolQ exbB proton channel
CAI14_06895	ENOG4105C4X	radical SAM domain protein
CAI14_06915	ENOG4108VYJ	response regulator receiver protein
CAI14_06920	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CAI14_06930	ENOG4105FZW	flagellar biosynthesis regulator FlhF
CAI14_06935	ENOG4105D7B	Flagellar biosynthesis protein flha
CAI14_06940	ENOG4105D00	flagellar biosynthetic protein flhB
CAI14_06960	ENOG4105BZU	Histidine kinase
CAI14_06965	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
CAI14_06970	ENOG4105VS8	Flagellar biosynthetic protein fliq
CAI14_06975	ENOG4105CN7	Flagellar biosynthetic protein FliP
CAI14_06985	ENOG4105DD5	Flagellar motor switch protein
CAI14_06990	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
CAI14_07010	ENOG4108JIR	Flagellum-specific ATP synthase
CAI14_07020	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
CAI14_07025	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
CAI14_07030	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
CAI14_07035	ENOG4107RGC	Glycosyl transferase, family 2
CAI14_07075	ENOG4105CHR	reductase
CAI14_07080	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
CAI14_07125	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
CAI14_07130	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CAI14_07150	ENOG4105MQ3	flagellar protein FliS
CAI14_07155	ENOG4107W9T	flagellar hook-associated
CAI14_07165	ENOG4105DTJ	flagellar hook-associated protein
CAI14_07175	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
CAI14_07180	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
CAI14_07185	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
CAI14_07190	ENOG4105CGA	flagellar basal-body rod protein FlgG
CAI14_07200	ENOG4108KPB	Flagellar basal-body rod protein FlgF
CAI14_07210	ENOG4105BZE	flagellar hook protein, FlgE
CAI14_07215	ENOG410822I	Flagellar hook capping protein
CAI14_07220	ENOG4108ZC9	flagellar basal-body rod protein flgc
CAI14_07250	ENOG4105BZU	Histidine kinase
CAI14_07255	ENOG4105BZU	Histidine kinase
CAI14_07285	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
CAI14_07300	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CAI14_07310	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
CAI14_07320	ENOG4105C3M	thioredoxin reductase
CAI14_07325	ENOG4105CNU	cell division protein FtsK
CAI14_07335	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
CAI14_07345	ENOG4105D1H	recombination factor protein RarA
CAI14_07350	ENOG41082MI	Protein CrcB homolog
CAI14_07360	ENOG4105CHU	acetyl-coa acetyltransferase
CAI14_07380	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
CAI14_07390	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
CAI14_07400	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
CAI14_07405	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
CAI14_07410	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
CAI14_07420	ENOG4105D06	uba thif-type nad fad binding protein
CAI14_07460	ENOG4105CGK	Exodeoxyribonuclease III
CAI14_07475	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
CAI14_07485	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
CAI14_07525	ENOG4108N8X	transition metal ion binding
CAI14_07555	ENOG4108ZXC	Two component transcriptional regulator, luxr family
CAI14_07575	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
CAI14_07605	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
CAI14_07610	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CAI14_07615	ENOG4105BZU	Histidine kinase
CAI14_07620	ENOG4106BRA	Membrane
CAI14_07650	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
CAI14_07655	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
CAI14_07665	ENOG4105CSH	Transporter
CAI14_07670	ENOG4105W3S	hemerythrin-like, metal-binding protein
CAI14_07680	ENOG4105CJP	fad dependent oxidoreductase
CAI14_07685	ENOG4105CFQ	glutamine synthetase
CAI14_07700	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
CAI14_07705	ENOG4107RUE	extracellular solute-binding protein family 1
CAI14_07725	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CAI14_07730	ENOG4105F38	ABC transporter, permease
CAI14_07735	ENOG4105D38	putrescine abc transporter
CAI14_07755	ENOG4108JU5	Magnesium and cobalt efflux protein
CAI14_07765	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
CAI14_07775	ENOG4105C9A	Phoh family
CAI14_07780	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
CAI14_07795	ENOG4105E4C	Lytic transglycosylase catalytic
CAI14_07810	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
CAI14_07815	ENOG4105EIX	cytochrome c1
CAI14_07820	ENOG4107MKT	Stringent starvation protein a
CAI14_07825	ENOG4105KB2	stringent starvation protein b
CAI14_07845	ENOG4107QRT	dEAD DEAH box helicase
CAI14_07850	ENOG4108VX5	3-methyladenine DNA glycosylase
CAI14_07855	ENOG4105C8Q	Methyl-accepting chemotaxis
CAI14_07860	ENOG4108V3W	Chemotaxis protein, CheW
CAI14_07900	ENOG4105E6M	Sulphatase-modifying factor protein
CAI14_07915	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
CAI14_07920	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
CAI14_07925	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
CAI14_07930	ENOG4105K8N	protein family UPF0079, ATPase
CAI14_07935	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
CAI14_07940	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
CAI14_07970	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
CAI14_07980	ENOG4108C33	Resolvase
CAI14_08015	ENOG4105CBX	hi0933 family
CAI14_08020	ENOG4108VWS	Yaeq family
CAI14_08025	ENOG4105VEQ	Cold shock protein
CAI14_08030	ENOG4108RXX	maleylacetoacetate isomerase
CAI14_08040	ENOG4105CNG	UPF0061 protein
CAI14_08045	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
CAI14_08050	ENOG4105C1J	atp-dependent rna helicase
CAI14_08055	ENOG4105C5H	ABC transporter
CAI14_08075	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
CAI14_08080	ENOG4105ECY	inositol monophosphatase
CAI14_08095	ENOG4105BZU	Histidine kinase
CAI14_08100	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
CAI14_08105	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
CAI14_08115	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
CAI14_08120	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
CAI14_08125	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
CAI14_08190	ENOG4107FQ9	ethanolamine ammonia-lyase
CAI14_08195	ENOG4105CPD	ethanolamine ammonia-lyase
CAI14_08220	ENOG4105CD3	dihydroorotase
CAI14_08225	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
CAI14_08240	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
CAI14_08245	ENOG4105C8N	cysteinyl-tRNA synthetase
CAI14_08255	ENOG4105DBV	ornithine carbamoyltransferase
CAI14_08260	ENOG4105CDH	Citrulline--aspartate ligase
CAI14_08275	ENOG4105CAS	nag kinase
CAI14_08285	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
CAI14_08290	ENOG4105CH7	arginosuccinase
CAI14_08300	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
CAI14_08305	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
CAI14_08330	ENOG4105EKQ	RNA-directed DNA polymerase
CAI14_08340	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
CAI14_08345	ENOG4105C4M	(Ubiquinol oxidase) subunit I
CAI14_08350	ENOG4108JJ9	ABC, transporter
CAI14_08355	ENOG4108JJ8	(ABC) transporter
CAI14_08375	ENOG4105KWW	Biogenesis protein
CAI14_08385	ENOG4105DA4	cytochrome c-type biogenesis protein
CAI14_08390	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
CAI14_08400	ENOG41060IM	Heme exporter protein
CAI14_08405	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
CAI14_08410	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
CAI14_08415	ENOG4105CHM	Aminotransferase
CAI14_08435	ENOG4105FE9	pseudouridine synthase
CAI14_08440	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
CAI14_08445	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
CAI14_08450	ENOG4105K9H	YciI-like protein
CAI14_08480	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
CAI14_08485	ENOG4105DRS	transport system, permease
CAI14_08515	ENOG4105DWY	Agmatine deiminase
CAI14_08535	ENOG4105CAT	Cytidine monophosphate kinase
CAI14_08540	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
CAI14_08545	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
CAI14_08555	ENOG4105CFV	Tetratricopeptide repeat protein
CAI14_08560	ENOG4105ESV	Glycosyl transferase, family 4
CAI14_08570	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
CAI14_08580	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
CAI14_08590	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
CAI14_08595	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
CAI14_08600	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
CAI14_08605	ENOG4105EVH	UPF0753 protein
CAI14_08615	ENOG4105DND	Transcriptional regulator
CAI14_08635	ENOG4105WH1	Two component transcriptional regulator luxr family
CAI14_08650	ENOG4105CHJ	isochorismatase hydrolase
CAI14_08675	ENOG4107SFI	Major Facilitator superfamily
CAI14_08695	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
CAI14_08700	ENOG4105KST	dependent repressor
CAI14_08705	ENOG4108Z6B	deaminase
CAI14_08710	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
CAI14_08740	ENOG4108C33	Resolvase
CAI14_08825	ENOG4105XMH	SpoVT AbrB domain protein
CAI14_08860	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
CAI14_08880	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
CAI14_08890	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
CAI14_08915	ENOG4105BZM	domain protein
CAI14_08920	ENOG4105BZU	Histidine kinase
CAI14_08965	ENOG4105N7H	Cytochrome
CAI14_08995	ENOG4108UHU	Aldolase
CAI14_09000	ENOG4105C01	Dihydroxy-acid dehydratase
CAI14_09005	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
CAI14_09010	ENOG4105CHC	glucokinase (EC 2.7.1.2)
CAI14_09035	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
CAI14_09055	ENOG4105E33	succinate dehydrogenase
CAI14_09060	ENOG410681N	tpr repeat protein
CAI14_09070	ENOG4105D60	lipoprotein releasing system transmembrane protein
CAI14_09075	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CAI14_09085	ENOG4108EC8	DNA internalization-related competence protein ComEC
CAI14_09100	ENOG4105BZ1	(ABC) transporter
CAI14_09105	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
CAI14_09110	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
CAI14_09125	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
CAI14_09130	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
CAI14_09210	ENOG4105CEY	Amp-dependent synthetase and ligase
CAI14_09235	ENOG4107QQG	Dehydrogenase
CAI14_09245	ENOG4108V1T	peptidylprolyl cis-trans isomerase
CAI14_09255	ENOG4105C72	UPF0176 protein
CAI14_09265	ENOG4105C03	ribonuclease
CAI14_09270	ENOG4105EI2	Pseudouridine synthase
CAI14_09275	ENOG4108NST	exported protein
CAI14_09280	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
CAI14_09290	ENOG41090A4	Pterin carbinolamine dehydratase
CAI14_09295	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
CAI14_09385	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
CAI14_09420	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
CAI14_09425	ENOG4108RCM	Nitroreductase
CAI14_09440	ENOG4105W39	Membrane
CAI14_09475	ENOG4105C7I	Dehydrogenase
CAI14_09485	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
CAI14_09490	ENOG4105BZS	acriflavin resistance protein
CAI14_09500	ENOG4108M60	Transcriptional regulator
CAI14_09505	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
CAI14_09510	ENOG4105DE4	1-phosphofructokinase
CAI14_09515	ENOG4105DM4	PTS System
CAI14_09560	ENOG4107QT7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CAI14_09565	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CAI14_09570	ENOG4105VIE	preprotein translocase, subunit YajC
CAI14_09575	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
CAI14_09580	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
CAI14_09620	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
CAI14_09625	ENOG4105E08	Glycoside hydrolase, family 9
CAI14_09630	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
CAI14_09635	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
CAI14_09650	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
CAI14_09655	ENOG4106H78	methyltransferase
CAI14_09660	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
CAI14_09690	ENOG4105C26	Dehydrogenase
CAI14_09710	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
CAI14_09715	ENOG4105D4A	Cell wall formation (By similarity)
CAI14_09745	ENOG410841Q	phosphoesterase PA-phosphatase related protein
CAI14_09765	ENOG4108UYB	regulatoR
CAI14_09770	ENOG4105KU2	hydrolase family 5
CAI14_09825	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
CAI14_09830	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
CAI14_09835	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
CAI14_09840	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CAI14_09845	ENOG4105DJ0	Poly(A) Polymerase
CAI14_09855	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
CAI14_09860	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
CAI14_09885	ENOG4105C93	Xylose Isomerase
CAI14_09890	ENOG4105CMG	Carbohydrate kinase
CAI14_09940	ENOG4108RTU	Aldolase
CAI14_09945	ENOG4105CXK	mandelate racemase muconate lactonizing
CAI14_09955	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
CAI14_09960	ENOG4108Z4U	Ferredoxin
CAI14_09970	ENOG4107TUS	Dihydrodipicolinate synthase
CAI14_09985	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CAI14_09990	ENOG4108IAB	Phoh family
CAI14_10030	ENOG4105CWB	LysR family transcriptional Regulator
CAI14_10040	ENOG4107SDU	Methyl-accepting chemotaxis
CAI14_10060	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
CAI14_10065	ENOG4105Y3E	Modulates RecA activity (By similarity)
CAI14_10075	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
CAI14_10080	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
CAI14_10090	ENOG4107TH8	cina domain protein
CAI14_10095	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
CAI14_10105	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
CAI14_10110	ENOG4105EEI	dihydropteroate synthase
CAI14_10115	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
CAI14_10120	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
CAI14_10125	ENOG4105HBR	Rna-binding protein
CAI14_10135	ENOG4108K5P	(LipO)protein
CAI14_10140	ENOG4108UM1	dedA family
CAI14_10145	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
CAI14_10150	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
CAI14_10155	ENOG4108DG9	Smr protein MutS2
CAI14_10160	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
CAI14_10165	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
CAI14_10170	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
CAI14_10175	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
CAI14_10180	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
CAI14_10190	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
CAI14_10195	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
CAI14_10205	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CAI14_10220	ENOG4105CJ3	phosphate transporter
CAI14_10250	ENOG4105DEN	Luciferase family
CAI14_10255	ENOG41079KZ	Major Facilitator Superfamily
CAI14_10260	ENOG4105BZ1	(ABC) transporter
CAI14_10265	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CAI14_10290	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
CAI14_10325	ENOG4105EGZ	biosynthesis protein
CAI14_10380	ENOG4105EMN	RNA polymerase sigma factor
CAI14_10395	ENOG41060IM	Heme exporter protein
CAI14_10405	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
CAI14_10410	ENOG4105DA4	cytochrome c-type biogenesis protein
CAI14_10415	ENOG4107QX9	Thiol disulfide interChange protein
CAI14_10420	ENOG4105KWW	Biogenesis protein
CAI14_10445	ENOG4105BZU	Histidine kinase
CAI14_10470	ENOG4105C8Q	Methyl-accepting chemotaxis
CAI14_10495	ENOG4105CC0	LysR family Transcriptional regulator
CAI14_10500	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
CAI14_10505	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
CAI14_10520	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
CAI14_10530	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
CAI14_10535	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
CAI14_10540	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
CAI14_10580	ENOG4105CI2	imidazolone-5-propionate hydrolase
CAI14_10585	ENOG4105C84	Histidine ammonia-lyase
CAI14_10595	ENOG4105CGP	Urocanate hydratase
CAI14_10610	ENOG4105DZG	Dehydrogenase
CAI14_10615	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CAI14_10620	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
CAI14_10635	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
CAI14_10640	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
CAI14_10645	ENOG4105CIH	Imidazole acetol-phosphate transaminase
CAI14_10655	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
CAI14_10665	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
CAI14_10670	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
CAI14_10675	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
CAI14_10680	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
CAI14_10690	ENOG4105C5S	asparaginyl-tRNA synthetase
CAI14_10730	ENOG4105WH1	Two component transcriptional regulator luxr family
CAI14_10775	ENOG41077A9	carbonic anhydrase
CAI14_10780	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
CAI14_10790	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
CAI14_10795	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
CAI14_10805	ENOG4105CJB	Exodeoxyribonuclease I
CAI14_10830	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
CAI14_10835	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
CAI14_10875	ENOG4105KHC	sulfurtransferase
CAI14_10880	ENOG4105P8F	nudix hydrolase
CAI14_10885	ENOG4108V1T	peptidylprolyl cis-trans isomerase
CAI14_10890	ENOG4105E39	Enoyl-CoA hydratase
CAI14_10900	ENOG4105CSM	endonuclease III
CAI14_10905	ENOG4105CHH	sulfate transporter
CAI14_10930	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
CAI14_10935	ENOG4105C8U	phosphate abc transporter
CAI14_10940	ENOG4105E2Z	phosphate ABC transporter (Permease
CAI14_10945	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
CAI14_10950	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
CAI14_10960	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
CAI14_10965	ENOG4105BZU	Histidine kinase
CAI14_10970	ENOG4105C2N	RNA methyltransferase TrmH family group 3
CAI14_10980	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
CAI14_11000	ENOG4105C1G	acyl-Coa dehydrogenase
CAI14_11005	ENOG4105C1G	acyl-Coa dehydrogenase
CAI14_11010	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CAI14_11015	ENOG4105C3R	Methionine synthase
CAI14_11040	ENOG4105D7K	pfkb domain protein
CAI14_11050	ENOG4105ETE	Transcriptional regulator (LacI family
CAI14_11065	ENOG41069P5	Protein slyX homolog
CAI14_11070	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
CAI14_11075	ENOG4108V1T	peptidylprolyl cis-trans isomerase
CAI14_11090	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
CAI14_11095	ENOG4105CZV	ABC transporter
CAI14_11125	ENOG4105C37	(CBS) domain
CAI14_11135	ENOG4107QTF	adenylosuccinate lyase
CAI14_11155	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
CAI14_11160	ENOG4105C7S	Dehydrogenase
CAI14_11170	ENOG4108URH	decarboxylase
CAI14_11180	ENOG4105BZ1	(ABC) transporter
CAI14_11185	ENOG4105C5Q	Transcriptional regulator
CAI14_11225	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CAI14_11230	ENOG4105CFG	Acts as a chaperone (By similarity)
CAI14_11235	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CAI14_11240	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
CAI14_11245	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
CAI14_11250	ENOG41090R7	Ferric uptake
CAI14_11255	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
CAI14_11265	ENOG4108Z1B	Cyclase dehydrase
CAI14_11270	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
CAI14_11300	ENOG4106TD9	Diguanylate cyclase
CAI14_11310	ENOG4105BZU	Histidine kinase
CAI14_11350	ENOG4105CR8	Transcriptional regulator
CAI14_11360	ENOG4105CDV	Ompa motb domain protein
CAI14_11370	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
CAI14_11375	ENOG4105CDU	Replicative dna helicase
CAI14_11385	ENOG4105CAQ	asparagine synthetase
CAI14_11395	ENOG4108K3A	Glutathione S-transferase
CAI14_11405	ENOG4105C1G	acyl-Coa dehydrogenase
CAI14_11420	ENOG4105F8V	Hydrolase, tatD family
CAI14_11425	ENOG4105CUZ	uba thif-type nad fad binding protein
CAI14_11440	ENOG4105VEQ	Cold shock protein
CAI14_11450	ENOG4105HDD	phospholipase
CAI14_11470	ENOG4107GFK	fumarate
CAI14_11480	ENOG4105DP0	ferredoxin-NADP reductase
CAI14_11485	ENOG4108V06	Glutathione peroxidase
CAI14_11495	ENOG4105DGW	oligopeptidase A
CAI14_11525	ENOG4105DUX	Transporter
CAI14_11550	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
CAI14_11555	ENOG4105CW7	secretion protein, HlyD family
CAI14_11575	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CAI14_11590	ENOG4108UWD	Iron-storage protein
CAI14_11600	ENOG4108ESX	Receptor
CAI14_11610	ENOG4105CAQ	asparagine synthetase
CAI14_11615	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
CAI14_11620	ENOG4105KUZ	arsenate reductase
CAI14_11630	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
CAI14_11635	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
CAI14_11670	ENOG4105CE9	30S ribosomal protein S2
CAI14_11675	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
CAI14_11685	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
CAI14_11690	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
CAI14_11695	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
CAI14_11700	ENOG4105KNE	Phosphatidate cytidylyltransferase
CAI14_11705	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
CAI14_11710	ENOG4105DZP	Membrane-associated zinc metalloprotease
CAI14_11725	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CAI14_11730	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
CAI14_11735	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CAI14_11740	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CAI14_11745	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CAI14_11755	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
CAI14_11770	ENOG4108YXA	Membrane
CAI14_11820	ENOG4107QK5	Homocysteine s-methyltransferase
CAI14_11825	ENOG4108IQI	permease
CAI14_11830	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
CAI14_11835	ENOG4105DA5	(ABC) transporter
CAI14_11850	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
CAI14_11860	ENOG4108R3D	Electron transport complex
CAI14_11880	ENOG4105K6V	RNA polymerase
CAI14_11905	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
CAI14_11920	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
CAI14_11925	ENOG4105M4H	endoribonuclease L-psp
CAI14_11965	ENOG4105F27	Major Facilitator
CAI14_11980	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
CAI14_11990	ENOG4108YZY	peptidylprolyl cis-trans isomerase
CAI14_12010	ENOG4105KSC	Transcriptional regulator, TraR DksA family
CAI14_12025	ENOG4108VKG	metal-dependent hydrolase
CAI14_12050	ENOG4105CHU	acetyl-coa acetyltransferase
CAI14_12080	ENOG4107T0X	DNA ligase
CAI14_12090	ENOG4107T0X	DNA ligase
CAI14_12095	ENOG4107QRT	dEAD DEAH box helicase
CAI14_12110	ENOG4105VEQ	Cold shock protein
CAI14_12120	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
CAI14_12125	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
CAI14_12130	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
CAI14_12135	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
CAI14_12140	ENOG4108QDE	fad dependent oxidoreductase
CAI14_12145	ENOG4107ZXU	DSBA oxidoreductase
CAI14_12160	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
CAI14_12170	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
CAI14_12175	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
CAI14_12180	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
CAI14_12190	ENOG4105C3F	Signal peptidase i
CAI14_12195	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
CAI14_12200	ENOG4105C0H	protease
CAI14_12210	ENOG4105EMN	RNA polymerase sigma factor
CAI14_12230	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
CAI14_12235	ENOG4105E39	Enoyl-CoA hydratase
CAI14_12240	ENOG4105C1G	acyl-Coa dehydrogenase
CAI14_12245	ENOG4105C26	Dehydrogenase
CAI14_12260	ENOG4106FKC	arabinogalactan endo-1,4-beta-galactosidase
CAI14_12265	ENOG4105CNT	hydrolase family 2
CAI14_12285	ENOG4105CMM	transposase
CAI14_12310	ENOG4105CNA	YD repeat protein
CAI14_12315	ENOG4105CNA	YD repeat protein
CAI14_12370	ENOG4105C9K	Endothelin-converting enzyme 1
CAI14_12380	ENOG4105C9K	Endothelin-converting enzyme 1
CAI14_12405	ENOG4105DC8	reductase
CAI14_12410	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
CAI14_12420	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
CAI14_12425	ENOG4105K4H	Nlp p60 protein
CAI14_12430	ENOG4105K4H	Nlp p60 protein
CAI14_12440	ENOG41082K6	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
CAI14_12450	ENOG4105G6Z	alkaline phosphatase
CAI14_12460	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
CAI14_12465	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
CAI14_12470	ENOG4105CTB	Polyprenyl synthetase
CAI14_12515	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
CAI14_12520	ENOG4105N42	UPF0307 protein
CAI14_12525	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
CAI14_12535	ENOG4105QD6	exported protein
CAI14_12540	ENOG4105C03	ribonuclease
CAI14_12545	ENOG4108Z03	MAF-like protein
CAI14_12550	ENOG4105MPN	Membrane
CAI14_12570	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
CAI14_12585	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
CAI14_12600	ENOG4105C8T	Leucyl-tRNA synthetase
CAI14_12610	ENOG4107QR8	Thioredoxin
CAI14_12650	ENOG4105WG9	Conserved Protein
CAI14_12695	ENOG4105BZ1	(ABC) transporter
CAI14_12725	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
CAI14_12730	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CAI14_12735	ENOG4105BZU	Histidine kinase
CAI14_12745	ENOG4105FQP	Beta-lactamase
CAI14_12750	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
CAI14_12775	ENOG4105FE9	pseudouridine synthase
CAI14_12780	ENOG4105BZU	Histidine kinase
CAI14_12830	ENOG4105D03	DNA-3-methyladenine glycosylase II
CAI14_12845	ENOG4105CMQ	Chloride channel
CAI14_12870	ENOG4105UGU	tonB-dependent Receptor
CAI14_12915	ENOG4105F27	Major Facilitator
CAI14_12945	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
CAI14_12950	ENOG4105BZS	acriflavin resistance protein
CAI14_12955	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
CAI14_12965	ENOG4105MYN	Zinc uptake regulation protein
CAI14_12970	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
CAI14_12995	ENOG4105CT7	inner membrane cred family protein
CAI14_13005	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
CAI14_13020	ENOG4105D6S	protein involved in catabolism of external DNA
CAI14_13030	ENOG4108JA2	transcriptioN-repair coupling factor
CAI14_13045	ENOG4105CBS	Chea signal transduction histidine kinase
CAI14_13050	ENOG4105C8Q	Methyl-accepting chemotaxis
CAI14_13055	ENOG4108V3W	Chemotaxis protein, CheW
CAI14_13060	ENOG4105BZU	Histidine kinase
CAI14_13065	ENOG4105BZU	Histidine kinase
CAI14_13070	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
CAI14_13075	ENOG4107RZC	phospholipase d
CAI14_13090	ENOG41080IJ	Diacylglycerol kinase
CAI14_13120	ENOG4108UJV	acyl-CoA thioesterase i
CAI14_13125	ENOG4108I0Y	(ABC) transporter
CAI14_13135	ENOG4105E2B	Taurine dioxygenase
CAI14_13150	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
CAI14_13170	ENOG4105D05	Receptor
CAI14_13180	ENOG4105CPC	Aldo Keto reductase
CAI14_13190	ENOG4105D9N	nucleoside
CAI14_13195	ENOG4108RVA	ribokinase
CAI14_13205	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
CAI14_13210	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
CAI14_13225	ENOG4105D6F	Phosphatase
CAI14_13270	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
CAI14_13280	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
CAI14_13285	ENOG4105DXX	methyltransferase
CAI14_13365	ENOG4105SYT	Methylenetetrahydrofolate reductase
CAI14_13375	ENOG4105M6F	mutator MutT protein
CAI14_13380	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
CAI14_13395	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CAI14_13400	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
CAI14_13405	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
CAI14_13410	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
CAI14_13415	ENOG4105CPF	Cell wall formation (By similarity)
CAI14_13420	ENOG4105DFU	Cell wall formation (By similarity)
CAI14_13425	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
CAI14_13435	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
CAI14_13440	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
CAI14_13445	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
CAI14_13450	ENOG4105CJN	penicillin-binding protein
CAI14_13455	ENOG4106932	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
CAI14_13460	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
CAI14_13500	ENOG41082RQ	UPF0102 protein
CAI14_13505	ENOG4105S2T	inner membrane protein YbcI
CAI14_13510	ENOG4105CQB	FAD linked oxidase domain protein
CAI14_13540	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
CAI14_13545	ENOG4105C08	Histidine kinase
CAI14_13550	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
CAI14_13555	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
CAI14_13560	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
CAI14_13585	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
CAI14_13590	ENOG4107YIM	Involved in the transcription termination process (By similarity)
CAI14_13595	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
CAI14_13600	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
CAI14_13615	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
CAI14_13625	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
CAI14_13630	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
CAI14_13640	ENOG4105C5H	ABC transporter
CAI14_13655	ENOG4105JAB	phenazine biosynthesis protein, phzf family
CAI14_13660	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
CAI14_13675	ENOG4108QBQ	Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione (By similarity)
CAI14_13705	ENOG4105JJR	Histidine kinase
CAI14_13725	ENOG4105CY0	Metallo-Beta-Lactamase
CAI14_13730	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
CAI14_13735	ENOG4106RE7	Cytochrome
CAI14_13760	ENOG4105C94	Transporter
CAI14_13765	ENOG4105C26	Dehydrogenase
CAI14_13770	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
CAI14_13775	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CAI14_13785	ENOG4105CE4	GlcNAc 6-P deacetylase
CAI14_13790	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
CAI14_13795	ENOG4105ETE	Transcriptional regulator (LacI family
CAI14_13820	ENOG4105CNT	hydrolase family 2
CAI14_13845	ENOG4108RTD	type II secretion system protein K
CAI14_13855	ENOG4105X5Z	General secretion pathway protein I
CAI14_13860	ENOG4105VWV	general secretion pathway protein h
CAI14_13865	ENOG4108VAU	general secretion pathway protein G
CAI14_13870	ENOG4105D7Q	type ii secretion system
CAI14_13875	ENOG4107QHF	type ii secretion system protein e
CAI14_13880	ENOG4105GVR	general secretion pathway protein D
CAI14_13935	ENOG4105BZU	Histidine kinase
CAI14_13945	ENOG4105BZU	Histidine kinase
CAI14_13950	ENOG4105W4M	Transport-associated protein
CAI14_13955	ENOG4105D9R	oxidoreductase
CAI14_13960	ENOG4108J5G	6-phosphogluconate dehydrogenase
CAI14_14005	ENOG4105EGI	Transcriptional regulator
CAI14_14015	ENOG4105CN1	protease
CAI14_14020	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
CAI14_14025	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
CAI14_14040	ENOG4105DZ1	carboxypeptidase
CAI14_14050	ENOG4105K6T	rare lipoprotein A
CAI14_14055	ENOG4105CVE	Lytic murein transglycosylase
CAI14_14065	ENOG4105CNI	cell division protein FtsW
CAI14_14080	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
CAI14_14090	ENOG4107T4Z	adenosine kinase
CAI14_14095	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
CAI14_14115	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
CAI14_14210	ENOG4105BZU	Histidine kinase
CAI14_14215	ENOG4105ETX	regulatoR
CAI14_14225	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
CAI14_14270	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
CAI14_14280	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
CAI14_14310	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
CAI14_14320	ENOG4105ETE	Transcriptional regulator (LacI family
CAI14_14350	ENOG4105EIB	trna rrna methyltransferase
CAI14_14400	ENOG4105BZS	acriflavin resistance protein
CAI14_14405	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
CAI14_14410	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
CAI14_14415	ENOG4105C11	sulfate adenylyltransferase), subunit 2
CAI14_14420	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
CAI14_14425	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
CAI14_14430	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
CAI14_14450	ENOG4105BZU	Histidine kinase
CAI14_14465	ENOG4107R11	Transcriptional regulator
CAI14_14470	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
CAI14_14485	ENOG4108UVJ	appr-1-p processing domain protein
CAI14_14490	ENOG4107R1Y	fructose-bisphosphate aldolase
CAI14_14495	ENOG4105CA9	Pyruvate kinase
CAI14_14505	ENOG4105BZA	Phosphoglycerate kinase
CAI14_14530	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
CAI14_14545	ENOG4105EIF	outer membrane protein W
CAI14_14550	ENOG4105EIF	outer membrane protein W
CAI14_14560	ENOG4107S76	domain protein
CAI14_14565	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
CAI14_14570	ENOG4105E0C	molybdate abc transporter
CAI14_14575	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
CAI14_14610	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
CAI14_14620	ENOG4105DR5	peptidase
CAI14_14630	ENOG4105CNM	Receptor
CAI14_14635	ENOG4107SKW	Inherit from COG: Alpha beta hydrolase
CAI14_14640	ENOG4105CV1	Transketolase (EC 2.2.1.1)
CAI14_14645	ENOG4105CK2	sodium dicarboxylate symporter
CAI14_14660	ENOG4107QVM	von Willebrand factor, type A
CAI14_14680	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
CAI14_14710	ENOG4108JQC	penicillin-binding protein 1A
CAI14_14735	ENOG4105DU0	nucleoside hydrolase
CAI14_14740	ENOG4105CB5	ATP-dependent DNA helicase recG
CAI14_14745	ENOG4105KME	endoribonuclease L-psp
CAI14_14750	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
CAI14_14755	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
CAI14_14760	ENOG4105DKT	Transcriptional regulator
CAI14_14775	ENOG4105TW1	Carbohydrate-selective porin OprB
CAI14_14790	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CAI14_14795	ENOG4105CHR	reductase
CAI14_14800	ENOG4108EMV	Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity)
CAI14_14810	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
CAI14_14815	ENOG4105DSJ	YicC domain protein
CAI14_14820	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
CAI14_14830	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
CAI14_14835	ENOG4105CSA	Coproporphyrinogen iii oxidase
CAI14_14850	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
CAI14_14860	ENOG4107RAQ	aminopeptidase
CAI14_14875	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
CAI14_14885	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
CAI14_14895	ENOG4105E66	phosphoriboisomerase A
CAI14_14905	ENOG41063JG	Transcriptional regulator
CAI14_14910	ENOG4105VCQ	rubredoxin
CAI14_14915	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
CAI14_14930	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
CAI14_14935	ENOG41061ZR	Transcriptional regulator
CAI14_14945	ENOG4105CIH	Imidazole acetol-phosphate transaminase
CAI14_14975	ENOG4105C8Y	Acetylornithine aminotransferase
CAI14_14980	ENOG4105EYW	Ion transport protein
CAI14_15000	ENOG410841Q	phosphoesterase PA-phosphatase related protein
CAI14_15005	ENOG4105FFC	UPF0187 protein
CAI14_15015	ENOG4105DFU	Cell wall formation (By similarity)
CAI14_15020	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
CAI14_15045	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CAI14_15055	ENOG4105F0N	pyrophosphate phospho-hydrolase
CAI14_15080	ENOG4105ECQ	AraC Family Transcriptional Regulator
CAI14_15085	ENOG4108M3R	transcriptional activator CadC
CAI14_15090	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
CAI14_15105	ENOG4105C8Q	Methyl-accepting chemotaxis
CAI14_15115	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
CAI14_15130	ENOG4105C7B	Threonine dehydratase
CAI14_15135	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
CAI14_15140	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
CAI14_15145	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CAI14_15150	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CAI14_15155	ENOG4108MP6	LysR family Transcriptional regulator
CAI14_15170	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
CAI14_15175	ENOG4105DFG	type I secretion outer membrane protein
CAI14_15180	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
CAI14_15185	ENOG4105D1S	lipid A biosynthesis
CAI14_15210	ENOG4105C6K	Malic enzyme
CAI14_15215	ENOG4105CK2	sodium dicarboxylate symporter
CAI14_15225	ENOG4105CQZ	Histidine kinase
CAI14_15235	ENOG4105CSH	Transporter
CAI14_15245	ENOG4105F04	LysR family Transcriptional regulator
CAI14_15255	ENOG4105CPC	Aldo Keto reductase
CAI14_15275	ENOG4105WH1	Two component transcriptional regulator luxr family
CAI14_15285	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
CAI14_15290	ENOG4105DHQ	Histidine kinase
CAI14_15310	ENOG4105D4T	Citrate transporter
CAI14_15315	ENOG4105CHR	reductase
CAI14_15320	ENOG4105ETE	Transcriptional regulator (LacI family
CAI14_15335	ENOG4107QW3	Sucrose phosphorylase
CAI14_15350	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
CAI14_15385	ENOG4105CD8	aminopeptidase N
CAI14_15390	ENOG41064RH	membrane protein YliF
CAI14_15395	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CAI14_15420	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
CAI14_15425	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
CAI14_15430	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CAI14_15440	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
CAI14_15450	ENOG4105WD1	Membrane
CAI14_15510	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
CAI14_15515	ENOG4108NEV	two component transcriptional regulator, LytTR family
CAI14_15520	ENOG4108HRK	Histidine kinase
CAI14_15530	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
CAI14_15550	ENOG4105BZU	Histidine kinase
CAI14_15560	ENOG4105CHH	sulfate transporter
CAI14_15565	ENOG4106R7G	Glycoside hydrolase family 5
CAI14_15570	ENOG4105C8Q	Methyl-accepting chemotaxis
CAI14_15630	ENOG4105E53	ec 3.2.1.28
CAI14_15660	ENOG4105F87	Dehydratase
CAI14_15665	ENOG4105DFI	Membrane
CAI14_15690	ENOG4105BZU	Histidine kinase
CAI14_15700	ENOG4107QS8	(LipO)protein
CAI14_15710	ENOG4105C5Z	peptidase
CAI14_15720	ENOG4105EYF	MMPL domain protein
CAI14_15745	ENOG4105CHF	Glutathione S-transferase
CAI14_15760	ENOG4105PDP	Short chain dehydrogenase
CAI14_15775	ENOG4107GJV	short-chain dehydrogenase reductase
CAI14_15810	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
CAI14_15850	ENOG4105DRR	Transcriptional regulator, GntR family
CAI14_15870	ENOG41065ZS	Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme- A to the apo- acyl-carrier-protein of the malonate decarboxylase to yield holo- acyl-carrier-protein (By similarity)
CAI14_15885	ENOG4105WSE	Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity)
CAI14_15915	ENOG4108YYC	ycei family
CAI14_15920	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
CAI14_15940	ENOG4105EX9	Membrane
CAI14_15945	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
CAI14_15970	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
CAI14_15985	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
CAI14_15995	ENOG4108K8S	endonuclease I
CAI14_16005	ENOG4105E1F	short-chain dehydrogenase reductase
CAI14_16020	ENOG4105VV6	START domain-containing protein
CAI14_16035	ENOG4105VF7	tolerance protein
CAI14_16040	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
CAI14_16045	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
CAI14_16050	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
CAI14_16060	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
CAI14_16080	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
CAI14_16105	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
CAI14_16110	ENOG4108HPI	phosphatidate Cytidylyltransferase
CAI14_16135	ENOG41077RS	Phosphatase
CAI14_16140	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
CAI14_16145	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
CAI14_16150	ENOG4105DC1	bifunctional purine biosynthesis protein purh
CAI14_16160	ENOG4105C12	Phosphoribosylglycinamide synthetase
CAI14_16170	ENOG4105EM2	membrane
CAI14_16185	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
CAI14_16205	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
CAI14_16225	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
CAI14_16250	ENOG4105BZU	Histidine kinase
CAI14_16255	ENOG4108UQY	Iron-storage protein
CAI14_16265	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
CAI14_16280	ENOG4108UJD	30S ribosomal protein S9
CAI14_16290	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
CAI14_16300	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
CAI14_16305	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
CAI14_16315	ENOG4105DK0	Indole-3-glycerol phosphate synthase
CAI14_16320	ENOG4108I0Q	anthranilate phosphoribosyltransferase
CAI14_16330	ENOG4105DDQ	anthranilate synthase
CAI14_16340	ENOG4105CRQ	synthase (Component I)
CAI14_16345	ENOG4107TE5	Lipid kinase
CAI14_16350	ENOG4105KD7	acetyltransferase
CAI14_16365	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
CAI14_16370	ENOG4105C8V	SAICAR synthetase
CAI14_16390	ENOG4105NVB	glycoside hydrolase, family 19
CAI14_16415	ENOG4105D65	subunit l
CAI14_16420	ENOG4108ZE9	Monovalent cation H antiporter subunit C
CAI14_16425	ENOG4107R4Z	monovalent cation h antiporter subunit d
CAI14_16435	ENOG4105W4C	monovalent cation H antiporter subunit F
CAI14_16440	ENOG4105KJM	monovalent cation h antiporter subunit g
CAI14_16460	ENOG4105F1J	Homogentisate 1,2-dioxygenase
CAI14_16470	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
CAI14_16485	ENOG4105DUX	Transporter
CAI14_16490	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
CAI14_16505	ENOG4107RUY	(E1 component), alpha subunit
CAI14_16510	ENOG4105CPP	Dehydrogenase, E1 component
CAI14_16525	ENOG4105C1J	atp-dependent rna helicase
CAI14_16540	ENOG4105CHR	reductase
CAI14_16545	ENOG4105BZS	acriflavin resistance protein
CAI14_16580	ENOG4107ZQV	short-chain dehydrogenase reductase
CAI14_16585	ENOG4105K4T	epimerase
CAI14_16610	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
CAI14_16615	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
CAI14_16620	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
CAI14_16630	ENOG4105CKW	Inner membrane protein yedI
CAI14_16645	ENOG4107RES	phosphoglycerol transferase I
CAI14_16650	ENOG4105EGS	Mechanosensitive ion channel
CAI14_16665	ENOG4105FTC	Lytic transglycosylase catalytic
CAI14_16680	ENOG4108TN6	type iii secretion
CAI14_16690	ENOG4108JIR	Flagellum-specific ATP synthase
CAI14_16705	ENOG4107Y59	type iii secretion
CAI14_16725	ENOG4108HR8	type iii secretion
CAI14_16745	ENOG4105VS8	Flagellar biosynthetic protein fliq
CAI14_16810	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
CAI14_16815	ENOG41081UC	Inherit from COG: Competence protein
CAI14_16820	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
CAI14_16825	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
CAI14_16835	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
CAI14_16840	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
CAI14_16875	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
CAI14_16880	ENOG4105MH3	Protein of unknown function (DUF2490)
CAI14_16895	ENOG4107HP6	Transcriptional regulator
CAI14_16905	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
CAI14_16910	ENOG4105F2Z	3-oxoadipate enol-lactonase
CAI14_16915	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
CAI14_16930	ENOG4105CHU	acetyl-coa acetyltransferase
CAI14_16960	ENOG4105E98	transcriptional regulator DeoR family
CAI14_16965	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
CAI14_16970	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
CAI14_16975	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
CAI14_16985	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
CAI14_17020	ENOG4105CPI	Metal Dependent Phosphohydrolase
CAI14_17025	ENOG4105D2S	major facilitator superfamily
CAI14_17035	ENOG4108Z0R	Transferase
CAI14_17050	ENOG4105C01	Dihydroxy-acid dehydratase
CAI14_17100	ENOG4105ECR	NmrA family
CAI14_17115	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
CAI14_17130	ENOG4108UZX	fmn reductase
CAI14_17135	ENOG4105DZ2	Transcriptional regulator
CAI14_17140	ENOG4105WPN	DNA integration recombination invertion protein
CAI14_17155	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
CAI14_17160	ENOG4105BZS	acriflavin resistance protein
CAI14_17165	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
CAI14_17170	ENOG4105EB3	Histidine kinase
CAI14_17175	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
CAI14_17195	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
CAI14_17200	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
CAI14_17215	ENOG4105D94	Major Facilitator Superfamily
CAI14_17220	ENOG4106NZI	LysR family Transcriptional regulator
CAI14_17240	ENOG4105F8V	Hydrolase, tatD family
CAI14_17245	ENOG4105ETT	transcriptional Regulator, LysR family
CAI14_17265	ENOG4105C7N	Xanthine uracil vitamin C permease
CAI14_17275	ENOG4105DU0	nucleoside hydrolase
CAI14_17285	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
CAI14_17295	ENOG4107RTG	Major Facilitator superfamily
CAI14_17300	ENOG4105EQ2	LysR family Transcriptional regulator
CAI14_17310	ENOG4105C5R	Aminotransferase
CAI14_17330	ENOG4105E1J	oxidoreductase
CAI14_17335	ENOG4105VT2	5-hydroxyisourate hydrolase
CAI14_17340	ENOG4108W15	Protein of unknown function (DUF1456)
CAI14_17345	ENOG4105CQ7	ATP-dependent helicase
CAI14_17360	ENOG4108R99	pseudouridine synthase
CAI14_17375	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
CAI14_17405	ENOG4108ZHJ	Organic hydroperoxide resistance protein
CAI14_17410	ENOG4105K56	Transcriptional regulator
CAI14_17415	ENOG4105D6Z	AFG1 family ATPase
CAI14_17435	ENOG4105CKI	cobalamin synthesis protein
CAI14_17490	ENOG4108RZE	Tetr family transcriptional regulator
CAI14_17495	ENOG4105C1G	acyl-Coa dehydrogenase
CAI14_17500	ENOG4107QX3	carboxylase
CAI14_17540	ENOG4105BZU	Histidine kinase
CAI14_17550	ENOG4107QP3	malate synthase g
CAI14_17555	ENOG4107R11	Transcriptional regulator
CAI14_17590	ENOG4105DGW	oligopeptidase A
CAI14_17595	ENOG4105D44	asparaginase
CAI14_17605	ENOG4108YZN	class I peptide chain release factor
CAI14_17615	ENOG4105DR9	pseudouridine synthase
CAI14_17625	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
CAI14_17650	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
CAI14_17655	ENOG410680H	amp-dependent synthetase and ligase
CAI14_17660	ENOG4105PI0	Ferredoxin
CAI14_17665	ENOG4108J2P	Alpha beta hydrolase fold
CAI14_17670	ENOG4107R3N	Filamentation induced by cAMP protein fic
CAI14_17675	ENOG4105E2T	synthase III
CAI14_17690	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
CAI14_17710	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CAI14_17715	ENOG4108TQ9	Histidine kinase
CAI14_17720	ENOG4105C7K	acetolactate synthase
CAI14_17725	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CAI14_17730	ENOG4105CN7	Flagellar biosynthetic protein FliP
CAI14_17740	ENOG4105DD5	Flagellar motor switch protein
CAI14_17750	ENOG4105BZE	flagellar hook protein, FlgE
CAI14_17755	ENOG410822I	Flagellar hook capping protein
CAI14_17795	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
CAI14_17800	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
CAI14_17815	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
CAI14_17820	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
CAI14_17830	ENOG4105CGA	flagellar basal-body rod protein FlgG
CAI14_17835	ENOG4108JQA	flagellar
CAI14_17840	ENOG4105D7B	Flagellar biosynthesis protein flha
CAI14_17845	ENOG4105D00	flagellar biosynthetic protein flhB
CAI14_17900	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
CAI14_17905	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
CAI14_17910	ENOG4107YZP	Rhodanese domain protein
CAI14_17945	ENOG4105CHU	acetyl-coa acetyltransferase
CAI14_17960	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
CAI14_17965	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
CAI14_17970	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CAI14_17975	ENOG4105CUX	Signal transduction histidine kinase
CAI14_17980	ENOG4105BZU	Histidine kinase
CAI14_17990	ENOG4105C5F	glutamine synthetase
CAI14_18000	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
CAI14_18040	ENOG4105KA0	thioesterase Superfamily protein
CAI14_18045	ENOG4107RZC	phospholipase d
CAI14_18055	ENOG4105M4E	phosphohistidine phosphatase, SixA
CAI14_18060	ENOG4105D1F	ATP-binding protein
CAI14_18125	ENOG4105E90	ABC transporter
CAI14_18130	ENOG4108IJ8	ABC transporter
CAI14_18145	ENOG4105DKW	ABC transporter
CAI14_18155	ENOG4105D78	K07001 NTE family protein
CAI14_18160	ENOG4105CNM	Receptor
CAI14_18165	ENOG4108YXU	transcriptional regulator AsnC family
CAI14_18170	ENOG4105MIR	Phenylalanine 4-monooxygenase
CAI14_18185	ENOG4107TDE	lipolytic protein G-D-S-L family
CAI14_18195	ENOG4105CHR	reductase
CAI14_18200	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
CAI14_18215	ENOG4105ETE	Transcriptional regulator (LacI family
CAI14_18220	ENOG4105DSG	hydrolase family 43
CAI14_18225	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CAI14_18235	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
CAI14_18250	ENOG4105EBR	Carboxylesterase
CAI14_18265	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
CAI14_18270	ENOG4105CG3	alpha amylase, catalytic region
CAI14_18275	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
CAI14_18360	ENOG4105RKW	reductase (By
CAI14_18395	ENOG4105E55	glycerol-3-phosphate acyltransferase
CAI14_18410	ENOG4105ETE	Transcriptional regulator (LacI family
CAI14_18425	ENOG4105QV4	Tryptophan halogenase
CAI14_18430	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
CAI14_18435	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
CAI14_18445	ENOG4108YXG	UPF0502 protein
CAI14_18455	ENOG4105KNA	-acetyltransferase
CAI14_18460	ENOG4105C4R	Atp-dependent dna helicase
CAI14_18480	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
CAI14_18510	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
CAI14_18515	ENOG4105DR5	peptidase
CAI14_18520	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
CAI14_18530	ENOG4105EYM	Major Facilitator superfamily
CAI14_18535	ENOG4105CGK	Exodeoxyribonuclease III
CAI14_18540	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
CAI14_18550	ENOG4107QJE	Chromosome Partitioning Protein
CAI14_18555	ENOG4105FA0	parb-like partition protein
CAI14_18575	ENOG4105CKK	Glycosyl transferase, family 2
CAI14_18590	ENOG4107QKV	phosphomannomutase
CAI14_18595	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
CAI14_18600	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
CAI14_18605	ENOG4105W5Q	DNA repair protein (RadC
CAI14_18610	ENOG4105C75	arginyL-tRNA synthetase
CAI14_18625	ENOG4105EMU	Dehydrogenase
CAI14_18630	ENOG4105EXC	Acyl-transferase
CAI14_18640	ENOG4105CEY	Amp-dependent synthetase and ligase
CAI14_18645	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
CAI14_18650	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
CAI14_18690	ENOG4108YZA	Nitrogen regulatory protein pii
CAI14_18695	ENOG4105W0Z	cytoplasmic protein
CAI14_18700	ENOG4105C0P	Mg chelatase subunit ChlI
CAI14_18715	ENOG41066DG	(EAL) domain protein
CAI14_18730	ENOG4105EJ2	Transcriptional regulator
CAI14_18750	ENOG4105E0Y	RtcB Protein
CAI14_18785	ENOG4105ECP	epimerase
CAI14_18790	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
CAI14_18795	ENOG4105DHQ	Histidine kinase
CAI14_18825	ENOG4105C0H	protease
CAI14_18845	ENOG4105DSF	transport protein
CAI14_18850	ENOG4107URF	beta-phospho-glucomutase
CAI14_18855	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
CAI14_18870	ENOG4107VGR	Catalase
CAI14_18895	ENOG4108S01	response regulator
CAI14_18900	ENOG4108ZGX	Histidine kinase
CAI14_18905	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
CAI14_18910	ENOG4105C19	ABC transporter
CAI14_18940	ENOG4105FDR	Membrane
CAI14_18960	ENOG4108NNI	Beta-lactamase domain-containing protein
CAI14_18965	ENOG4105C31	Tryptophanyl-tRNA synthetase
CAI14_18970	ENOG4105VDW	Csbd family
CAI14_19070	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
CAI14_19100	ENOG4105EB3	Histidine kinase
CAI14_19105	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
CAI14_19115	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
CAI14_19135	ENOG4105CH6	catalase
CAI14_19145	ENOG4105DVT	helicase
CAI14_19160	ENOG4105E2X	shikimate dehydrogenase
CAI14_19170	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
CAI14_19195	ENOG4105D52	delta-aminolevulinic acid dehydratase
CAI14_19225	ENOG4105CYM	Glutathione S-transferase
CAI14_19265	ENOG4108IUW	ABC transporter
CAI14_19275	ENOG4105VZ8	Transcriptional regulator
CAI14_19295	ENOG4105PGM	cation diffusion facilitator family transporter
CAI14_19305	ENOG4105E0K	tonB-dependent siderophore receptor
CAI14_19315	ENOG4105ECQ	AraC Family Transcriptional Regulator
CAI14_19320	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
CAI14_19325	ENOG4105DA5	(ABC) transporter
CAI14_19330	ENOG4105E3A	(ABC) transporter
CAI14_19340	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
CAI14_19375	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CAI14_19385	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CAI14_19400	ENOG4105CD5	CoA-binding domain protein
CAI14_19425	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
CAI14_19430	ENOG4105BZP	glycoside hydrolase 15-related
CAI14_19450	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
CAI14_19510	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
CAI14_19515	ENOG4105E9Q	Acyl-transferase
CAI14_19525	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
CAI14_19555	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
CAI14_19575	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
CAI14_19585	ENOG4105C2M	dna polymerase I
CAI14_19620	ENOG4108ZF3	Phosphatase
CAI14_19655	ENOG4105CS6	Rhs element vgr protein
CAI14_19700	ENOG4105D6F	Phosphatase
CAI14_19770	ENOG4108WC9	type VI secretion system effector, hcp1 family
CAI14_19815	ENOG4105C4R	Atp-dependent dna helicase
CAI14_19830	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
CAI14_19835	ENOG4108KB2	LysR family Transcriptional regulator
CAI14_19840	ENOG4105JSC	dimethylmenaquinone methyltransferase
CAI14_19855	ENOG4105KHM	amidohydrolase 2
CAI14_19885	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
CAI14_19905	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
CAI14_19910	ENOG4105DGI	Alkaline phosphatase
CAI14_19935	ENOG4105CGK	Exodeoxyribonuclease III
CAI14_19940	ENOG4105E2R	ROK family
CAI14_19950	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
CAI14_19960	ENOG4107QN1	sodium solute
CAI14_19965	ENOG41062QD	Membrane
CAI14_19975	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
CAI14_20015	ENOG4105DSG	hydrolase family 43
CAI14_20035	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
CAI14_20040	ENOG4105ERH	Fumarylacetoacetate hydrolase
CAI14_20050	ENOG4105DIA	mandelate racemase muconate lactonizing
CAI14_20055	ENOG4105QJH	Domain of unknown function (DUF718)
CAI14_20060	ENOG4105EDR	glucose galactose transporter
CAI14_20065	ENOG4108K2P	TRANSCRIPTIONal
CAI14_20075	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
CAI14_20080	ENOG4105BZU	Histidine kinase
CAI14_20095	ENOG4105E2V	Glycosyltransferase 36
CAI14_20100	ENOG4105CT4	transporter
CAI14_20105	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
CAI14_20135	ENOG4105MA0	exported protein
CAI14_20140	ENOG4105CFU	surface antigen
CAI14_20190	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
CAI14_20210	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
CAI14_20220	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
CAI14_20225	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
CAI14_20240	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
CAI14_20265	ENOG4105DH7	May be involved in recombination (By similarity)
CAI14_20270	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
CAI14_20280	ENOG4105C93	Xylose Isomerase
CAI14_20285	ENOG4105ETE	Transcriptional regulator (LacI family
CAI14_20300	ENOG4105CXK	mandelate racemase muconate lactonizing
CAI14_20315	ENOG4105DEI	Mannitol dehydrogenase
CAI14_20360	ENOG4105EVH	UPF0753 protein
CAI14_20415	ENOG4108C33	Resolvase
CAI14_20465	ENOG4106RHG	Yeca family
CAI14_20485	ENOG4108C33	Resolvase
CAI14_20505	ENOG41082W1	Cupin 2, conserved barrel domain protein
CAI14_20520	ENOG4105CGF	Aromatic amino acid aminotransferase
CAI14_20525	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CAI14_20555	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
CAI14_20595	ENOG4105CSH	Transporter
CAI14_20605	ENOG4105K63	Thioredoxin
CAI14_20630	ENOG4105D4Y	metalloprotease
CAI14_20650	ENOG41067RQ	csbd family
CAI14_20675	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
CAI14_20690	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
CAI14_20695	ENOG4107FW0	short-chain dehydrogenase reductase
CAI14_20715	ENOG4108UT2	hemolysin iii
CAI14_20720	ENOG4108I5C	dEAD DEAH box helicase
CAI14_20820	ENOG4107W2Z	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) (By similarity)
CAI14_20850	ENOG4105BZ1	(ABC) transporter
CAI14_20865	ENOG4105CMR	udp-glucose 4-epimerase
CAI14_20900	ENOG4107RA4	Glycosyl transferase (Group 1
CAI14_20925	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
CAI14_20930	ENOG4105D3Q	Sugar transferase
CAI14_20950	ENOG4105EXG	Transcriptional regulator
CAI14_20980	ENOG4105CBC	glutamate synthase
CAI14_20985	ENOG4105BZ8	glutamate synthase
CAI14_20990	ENOG4105DQ4	alcohol dehydrogenase
CAI14_21030	ENOG4107VAM	peptidase, m28
CAI14_21040	ENOG41063SB	peptidase
CAI14_21045	ENOG4105CN1	protease
CAI14_21065	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
CAI14_21100	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
CAI14_21110	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
CAI14_21140	ENOG4108K0D	peptidase, M48
CAI14_21150	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CAI14_21155	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
CAI14_21160	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
CAI14_21165	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
CAI14_21175	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
CAI14_21180	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CAI14_21185	ENOG4108ZJ4	polysaccharide deacetylase
CAI14_21190	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
CAI14_21205	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
CAI14_21220	ENOG4105DU1	integral membrane protein, terc
CAI14_21230	ENOG4105DR4	Methyltransferase
CAI14_21260	ENOG4105NRM	Membrane
CAI14_21275	ENOG4105CUB	amino acid
CAI14_21285	ENOG4108TGY	Glutathione S-transferase
CAI14_21300	ENOG4105EJC	lysr family transcriptional regulator
CAI14_21305	ENOG4105CIS	alcohol dehydrogenase
CAI14_21310	ENOG4107QSV	RmuC domain protein
CAI14_21320	ENOG4108V06	Glutathione peroxidase
CAI14_21330	ENOG410903C	(LipO)protein
CAI14_21345	ENOG4107PE3	Mammalian cell entry related domain protein
CAI14_21350	ENOG4105CY3	ABC transporter, permease
CAI14_21355	ENOG4105DHJ	ABC, transporter
CAI14_21370	ENOG4105DSY	exodeoxyribonuclease V, gamma
CAI14_21375	ENOG4107QKA	exodeoxyribonuclease V beta
CAI14_21395	ENOG4105F2I	Transposase
CAI14_21510	ENOG4108SIC	Transcriptional regulator
CAI14_21520	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
CAI14_21565	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
CAI14_21575	ENOG4105CSH	Transporter
CAI14_21580	ENOG4105DR8	Membrane
CAI14_21590	ENOG4105Y49	secretion protein, HlyD family
CAI14_21595	ENOG4105ZQC	membrane protein AaeX
CAI14_21605	ENOG4105EUJ	GTP cyclohydrolase i
CAI14_21625	ENOG4105EJ9	Membrane
CAI14_21630	ENOG4105K5B	UPF0225 protein
CAI14_21640	ENOG4105DSB	aldose 1-epimerase
CAI14_21665	ENOG4105DKK	Benzoate
CAI14_21695	ENOG4105C26	Dehydrogenase
CAI14_21705	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
CAI14_21720	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
CAI14_21725	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
CAI14_21750	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
CAI14_21760	ENOG4105DHU	Bile acid
CAI14_21765	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
CAI14_21770	ENOG4107S2Z	UPF0761 membrane protein
CAI14_21780	ENOG4105KTH	gatB Yqey
CAI14_21790	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CAI14_21795	ENOG4107ZVW	dihydroneopterin aldolase
CAI14_21800	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
CAI14_21810	ENOG4108Z12	YiaAB two helix domain-containing protein
CAI14_21825	ENOG4105D5Q	Arginine ornithine antiporter
CAI14_21835	ENOG4105DTQ	mandelate racemase muconate lactonizing
CAI14_21845	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
CAI14_21850	ENOG4108UQS	dipeptidase
CAI14_21900	ENOG4105E32	cytoplasmic protein
CAI14_21910	ENOG4105BZS	acriflavin resistance protein
CAI14_21915	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
CAI14_21920	ENOG4105CH2	amidohydrolase
CAI14_21925	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
CAI14_21930	ENOG4109066	lysm domain bon superfamily protein
CAI14_21940	ENOG4105KCF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
CAI14_21945	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
CAI14_21965	ENOG4105FB9	CRISPR-associated protein
CAI14_21980	ENOG4105E9K	Isocitrate dehydrogenase
CAI14_21990	ENOG4105ETT	transcriptional Regulator, LysR family
CAI14_21995	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
CAI14_22000	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
CAI14_22010	ENOG4105C1J	atp-dependent rna helicase
CAI14_22015	ENOG4105CAK	Cell division ATP-binding protein ftsE
CAI14_22020	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
CAI14_22025	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CAI14_22030	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
CAI14_22035	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CAI14_22060	ENOG4108TGY	Glutathione S-transferase
CAI14_22065	ENOG4105C25	Primosomal protein n'
CAI14_22085	ENOG4107QI1	Mate efflux family protein
CAI14_22090	ENOG4105D07	Signal peptide peptidase, SppA
CAI14_22100	ENOG4107ZQV	short-chain dehydrogenase reductase
CAI14_22115	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CAI14_22120	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
CAI14_22140	ENOG4105C79	DNA protecting protein DprA
CAI14_22145	ENOG4108WZM	domain protein
CAI14_22150	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
CAI14_22155	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
CAI14_22160	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
CAI14_22205	ENOG4108Z7F	N-acetyltransferase
CAI14_22215	ENOG4105D1S	lipid A biosynthesis
CAI14_22220	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
CAI14_22225	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CAI14_22300	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
CAI14_22305	ENOG4105HEI	LysR family (Transcriptional regulator
CAI14_22320	ENOG4105C8Q	Methyl-accepting chemotaxis
CAI14_22335	ENOG4108UQ8	endoribonuclease L-psp
CAI14_22350	ENOG4105CIG	ABC transporter
CAI14_22410	ENOG4105E2A	Dehydrogenase
CAI14_22435	ENOG4105BZ1	(ABC) transporter
CAI14_22465	ENOG4105CMR	udp-glucose 4-epimerase
CAI14_22470	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
CAI14_22490	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
CAI14_22495	ENOG4105C4M	(Ubiquinol oxidase) subunit I
CAI14_22510	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CAI14_22525	ENOG4105BZU	Histidine kinase
CAI14_22545	ENOG4105WEF	catalase
CAI14_22550	ENOG4108Z9Z	response to DNA damage stimulus
CAI14_22575	ENOG4105C2F	Histidine kinase
CAI14_22580	ENOG4108VAC	response regulator
CAI14_22590	ENOG4107QTZ	amino acid
CAI14_22610	ENOG4105C9K	Endothelin-converting enzyme 1
CAI14_22615	ENOG4106WTF	Glycosyl transferase, family 2
CAI14_22625	ENOG4105CPC	Aldo Keto reductase
CAI14_22645	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
CAI14_22655	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
CAI14_22670	ENOG4105EEQ	Na H antiporter
CAI14_22675	ENOG4105DA5	(ABC) transporter
CAI14_22680	ENOG4105E3A	(ABC) transporter
CAI14_22710	ENOG4105ER2	Ompa motb domain protein
CAI14_22715	ENOG4107RD7	Flagellar Motor Protein, MotA
CAI14_22735	ENOG4105EW9	transcriptional regulator AsnC family
CAI14_22740	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
CAI14_22745	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
CAI14_22765	ENOG4105BZU	Histidine kinase
CAI14_22785	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
CAI14_22790	ENOG4105I08	Pseudouridine synthase
CAI14_22795	ENOG4107YBY	Hydrolase
CAI14_22800	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
CAI14_22820	ENOG4105BZU	Histidine kinase
CAI14_22830	ENOG4108VPT	UPF0234 protein
CAI14_22835	ENOG4108EHX	EamA-like transporter family
CAI14_22845	ENOG4108UMI	ABC transporter, permease
CAI14_22850	ENOG4105D01	(LipO)protein
CAI14_22890	ENOG4107QSN	dihydrolipoamide acetyltransferase
CAI14_22900	ENOG4107QN2	dihydrolipoyl dehydrogenase
CAI14_22920	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
CAI14_22925	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CAI14_22930	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CAI14_22980	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
CAI14_23095	ENOG4105CMA	conjugation trbi family protein
CAI14_23390	ENOG4105C0H	protease
CAI14_23430	ENOG4105C26	Dehydrogenase
CAI14_23505	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
CAI14_23565	ENOG4108NSC	Pfam:DUF88
CAI14_23635	ENOG4105C26	Dehydrogenase
CAI14_23650	ENOG4106RHG	Yeca family