locus-tag	class	description
CAI14_00005	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CAI14_00010	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CAI14_00015	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CAI14_00020	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CAI14_00025	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CAI14_00040	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CAI14_00045	COG4191	Histidine kinase
CAI14_00060	COG0577	efflux transmembrane transporter activity
CAI14_00065	COG0577	efflux transmembrane transporter activity
CAI14_00070	COG1136	(ABC) transporter
CAI14_00070	COG4591	ABC-type transport system involved in lipoprotein release permease component
CAI14_00075	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CAI14_00080	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CAI14_00120	COG2132	Multicopper oxidase
CAI14_00135	COG0339	signal peptide processing
CAI14_00150	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CAI14_00155	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CAI14_00170	COG2819	hydrolase of the alpha beta superfamily
CAI14_00180	COG1956	GAF domain-containing protein
CAI14_00190	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CAI14_00200	COG0720	synthase
CAI14_00210	COG4206	TonB-dependent receptor
CAI14_00220	COG0513	Belongs to the DEAD box helicase family
CAI14_00235	COG0625	glutathione transferase activity
CAI14_00265	COG0626	cystathionine gamma-synthase activity
CAI14_00285	COG0438	transferase activity, transferring glycosyl groups
CAI14_00285	COG1216	Glycosyl transferase, family 2
CAI14_00320	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CAI14_00335	COG0277	FAD linked oxidase domain protein
CAI14_00340	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CAI14_00340	COG0546	phosphoglycolate phosphatase activity
CAI14_00355	COG2086	electron transfer activity
CAI14_00385	COG0662	Cupin 2, conserved barrel domain protein
CAI14_00385	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CAI14_00390	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CAI14_00425	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CAI14_00425	COG3218	ABC-type transport auxiliary lipoprotein component
CAI14_00430	COG1127	ABC transporter
CAI14_00435	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CAI14_00450	COG0442	prolyl-tRNA aminoacylation
CAI14_00460	COG1183	phosphatidylcholine synthase activity
CAI14_00480	COG0741	lytic transglycosylase activity
CAI14_00500	COG0525	valine-tRNA ligase activity
CAI14_00515	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CAI14_00525	COG0795	lipopolysaccharide-transporting ATPase activity
CAI14_00540	COG4974	Belongs to the 'phage' integrase family
CAI14_00550	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CAI14_00560	COG0047	phosphoribosylformylglycinamidine synthase activity
CAI14_00560	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CAI14_00570	COG1404	Belongs to the peptidase S8 family
CAI14_00575	COG5295	Hep Hag repeat protein
CAI14_00580	COG1404	Belongs to the peptidase S8 family
CAI14_00585	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CAI14_00595	COG1459	type II secretion system
CAI14_00600	COG2165	general secretion pathway protein
CAI14_00605	COG4970	Tfp pilus assembly protein FimT
CAI14_00610	COG2165	general secretion pathway protein
CAI14_00615	COG4795	General secretion pathway protein
CAI14_00620	COG3156	type II secretion system protein K
CAI14_00625	COG3166	PFAM Fimbrial assembly family protein
CAI14_00640	COG1450	Type ii and iii secretion system protein
CAI14_00655	COG2188	Transcriptional regulator
CAI14_00720	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CAI14_00735	COG1215	transferase activity, transferring glycosyl groups
CAI14_00740	COG1215	transferase activity, transferring glycosyl groups
CAI14_00745	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CAI14_00750	COG0457	Tetratricopeptide repeat
CAI14_00780	COG0242	peptide deformylase activity
CAI14_00785	COG1307	EDD domain protein, DegV family
CAI14_00820	COG0402	S-adenosylhomocysteine deaminase activity
CAI14_00825	COG3964	amidohydrolase
CAI14_00840	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CAI14_00845	COG0726	polysaccharide deacetylase
CAI14_00875	COG0436	Aminotransferase
CAI14_00895	COG0237	dephospho-CoA kinase activity
CAI14_00900	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CAI14_00905	COG1459	type II secretion system
CAI14_00950	COG0045	succinate-CoA ligase (ADP-forming) activity
CAI14_00955	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CAI14_00965	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CAI14_00965	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CAI14_00975	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CAI14_00980	COG0564	pseudouridine synthase activity
CAI14_00995	COG3011	Protein conserved in bacteria
CAI14_01000	COG0840	transmembrane signaling receptor activity
CAI14_01020	COG3387	PFAM Glycoside hydrolase 15-related
CAI14_01025	COG1877	trehalose-phosphatase activity
CAI14_01070	COG2827	Endonuclease containing a URI domain
CAI14_01080	COG4771	TonB-dependent receptor
CAI14_01085	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CAI14_01090	COG0667	Aldo Keto reductase
CAI14_01095	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CAI14_01100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CAI14_01105	COG1116	anion transmembrane transporter activity
CAI14_01110	COG0542	response to heat
CAI14_01115	COG4206	TonB-dependent receptor
CAI14_01145	COG1492	cobalamin metabolic process
CAI14_01155	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CAI14_01185	COG0019	diaminopimelate decarboxylase activity
CAI14_01200	COG4264	IucA IucC family
CAI14_01210	COG4772	TonB-dependent receptor
CAI14_01235	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CAI14_01235	COG4651	solute:proton antiporter activity
CAI14_01275	COG0488	(ABC) transporter
CAI14_01315	COG0477	Major facilitator Superfamily
CAI14_01330	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CAI14_01345	COG0217	transcriptional regulatory protein
CAI14_01350	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CAI14_01355	COG0632	four-way junction helicase activity
CAI14_01360	COG3158	transport of potassium into the cell
CAI14_01370	COG2255	four-way junction helicase activity
CAI14_01375	COG0824	Thioesterase
CAI14_01385	COG0848	biopolymer transport protein
CAI14_01395	COG0823	Involved in the tonB-independent uptake of proteins
CAI14_01400	COG2885	chlorophyll binding
CAI14_01410	COG0602	queuosine metabolic process
CAI14_01420	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CAI14_01425	COG3920	Histidine kinase
CAI14_01445	COG0840	transmembrane signaling receptor activity
CAI14_01480	COG0514	ATP-dependent DNA helicase (RecQ)
CAI14_01490	COG0783	Belongs to the Dps family
CAI14_01495	COG1643	Atp-dependent helicase
CAI14_01525	COG0535	radical SAM domain protein
CAI14_01530	COG0535	radical SAM domain protein
CAI14_01535	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
CAI14_01540	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CAI14_01550	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CAI14_01570	COG1215	transferase activity, transferring glycosyl groups
CAI14_01575	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CAI14_01585	COG1199	ATP-dependent helicase activity
CAI14_01595	COG1397	ADP-ribosylglycohydrolase
CAI14_01605	COG0189	ligase activity
CAI14_01620	COG0835	chemotaxis
CAI14_01625	COG0840	transmembrane signaling receptor activity
CAI14_01630	COG0784	Response regulator, receiver
CAI14_01630	COG2198	Histidine kinase
CAI14_01630	COG0643	Histidine kinase
CAI14_01660	COG1446	asparaginase
CAI14_01665	COG3142	Participates in the control of copper homeostasis
CAI14_01705	COG3537	Alpha-1,2-mannosidase
CAI14_01740	COG1472	Belongs to the glycosyl hydrolase 3 family
CAI14_01755	COG1388	LysM domain
CAI14_01755	COG3858	chitin binding
CAI14_01770	COG0837	glucose binding
CAI14_01775	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CAI14_01785	COG0494	nUDIX hydrolase
CAI14_01795	COG3956	TIGRFAM MazG family protein
CAI14_01800	COG1742	UPF0060 membrane protein
CAI14_01825	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CAI14_01830	COG0509	glycine decarboxylation via glycine cleavage system
CAI14_01855	COG1960	acyl-CoA dehydrogenase activity
CAI14_01865	COG1309	transcriptional regulator
CAI14_01880	COG4771	TonB-dependent receptor
CAI14_01890	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CAI14_01895	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CAI14_01900	COG0463	Glycosyl transferase, family 2
CAI14_01905	COG0517	IMP dehydrogenase activity
CAI14_01905	COG0516	GMP reductase activity
CAI14_01910	COG2982	Protein involved in outer membrane biogenesis
CAI14_01915	COG1272	protein, Hemolysin III
CAI14_01920	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CAI14_01925	COG0739	heme binding
CAI14_01930	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CAI14_01935	COG0626	cystathionine gamma-synthase activity
CAI14_01940	COG0460	homoserine dehydrogenase
CAI14_01940	COG0527	aspartate kinase activity
CAI14_01955	COG1760	l-serine dehydratase
CAI14_01975	COG2353	YceI-like domain
CAI14_01980	COG2205	protein histidine kinase activity
CAI14_01980	COG0784	Response regulator, receiver
CAI14_01980	COG2198	Histidine kinase
CAI14_02000	COG0477	Major facilitator Superfamily
CAI14_02005	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CAI14_02015	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CAI14_02020	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CAI14_02025	COG0259	pyridoxamine-phosphate oxidase activity
CAI14_02035	COG1842	Phage shock protein A
CAI14_02060	COG0754	glutathionylspermidine amidase activity
CAI14_02070	COG2814	Major facilitator Superfamily
CAI14_02135	COG1234	tRNA 3'-trailer cleavage
CAI14_02165	COG0531	amino acid
CAI14_02170	COG2197	response regulator
CAI14_02200	COG1113	amino acid transport
CAI14_02220	COG1271	oxidase subunit
CAI14_02225	COG1294	oxidase, subunit
CAI14_02240	COG2239	Acts as a magnesium transporter
CAI14_02250	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CAI14_02255	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CAI14_02265	COG1660	Displays ATPase and GTPase activities
CAI14_02270	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CAI14_02275	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CAI14_02290	COG1137	ATPase activity
CAI14_02295	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CAI14_02305	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CAI14_02315	COG0271	Belongs to the BolA IbaG family
CAI14_02320	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CAI14_02340	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CAI14_02350	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CAI14_02360	COG0628	permease
CAI14_02370	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CAI14_02375	COG3178	'Phosphotransferase
CAI14_02390	COG1555	photosystem II stabilization
CAI14_02405	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CAI14_02410	COG1477	protein flavinylation
CAI14_02435	COG3128	pkhd-type hydroxylase
CAI14_02440	COG4774	siderophore transport
CAI14_02445	COG2146	nitrite reductase [NAD(P)H] activity
CAI14_02455	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CAI14_02460	COG0719	Fe-S assembly protein
CAI14_02465	COG0396	ATPase activity
CAI14_02470	COG0719	Fe-S assembly protein
CAI14_02475	COG1959	2 iron, 2 sulfur cluster binding
CAI14_02485	COG0693	protein deglycase activity
CAI14_02505	COG0739	heme binding
CAI14_02520	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CAI14_02535	COG5297	Belongs to the glycosyl hydrolase family 6
CAI14_02545	COG0519	Catalyzes the synthesis of GMP from XMP
CAI14_02555	COG1678	Uncharacterized ACR, COG1678
CAI14_02560	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CAI14_02565	COG0540	Belongs to the ATCase OTCase family
CAI14_02570	COG1764	response to oxidative stress
CAI14_02585	COG0384	phenazine biosynthesis protein PhzF
CAI14_02590	COG0527	aspartate kinase activity
CAI14_02605	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CAI14_02620	COG0142	geranyltranstransferase activity
CAI14_02625	COG0629	single-stranded DNA binding
CAI14_02630	COG5001	Diguanylate cyclase
CAI14_02630	COG4251	negative regulation of phosphorylation
CAI14_02630	COG3706	GGDEF domain
CAI14_02630	COG2203	Gaf domain
CAI14_02635	COG3321	synthase
CAI14_02635	COG1028	Short-chain dehydrogenase reductase Sdr
CAI14_02635	COG0604	alcohol dehydrogenase
CAI14_02640	COG2080	2 iron, 2 sulfur cluster binding
CAI14_02645	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CAI14_02650	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CAI14_02655	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CAI14_02705	COG2879	small protein
CAI14_02710	COG1966	Carbon starvation protein
CAI14_02715	COG1741	Belongs to the pirin family
CAI14_02740	COG1515	deoxyribonuclease V activity
CAI14_02745	COG0588	phosphoglycerate mutase activity
CAI14_02780	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CAI14_02785	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CAI14_02800	COG3829	transcription factor binding
CAI14_02810	COG1116	anion transmembrane transporter activity
CAI14_02815	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CAI14_02825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CAI14_02830	COG0431	NADPH-dependent FMN reductase
CAI14_02855	COG0747	negative chemotaxis
CAI14_02875	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CAI14_02880	COG2967	ApaG domain
CAI14_02885	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CAI14_02890	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CAI14_02895	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CAI14_02900	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CAI14_02905	COG0123	including yeast histone deacetylase and acetoin utilization protein
CAI14_02910	COG2096	Adenosyltransferase
CAI14_02925	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CAI14_02930	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CAI14_02960	COG3384	dioxygenase
CAI14_02965	COG0583	DNA-binding transcription factor activity
CAI14_02970	COG0318	PFAM AMP-dependent synthetase and ligase
CAI14_02980	COG1024	Enoyl-CoA hydratase
CAI14_03000	COG3386	PFAM SMP-30 Gluconolaconase
CAI14_03015	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
CAI14_03035	COG0697	spore germination
CAI14_03045	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CAI14_03080	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CAI14_03090	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CAI14_03095	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CAI14_03105	COG0583	DNA-binding transcription factor activity
CAI14_03110	COG3634	alkyl hydroperoxide reductase activity
CAI14_03120	COG2890	protein-(glutamine-N5) methyltransferase activity
CAI14_03140	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CAI14_03140	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CAI14_03170	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CAI14_03190	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CAI14_03210	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CAI14_03220	COG1404	Belongs to the peptidase S8 family
CAI14_03230	COG1404	Belongs to the peptidase S8 family
CAI14_03235	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CAI14_03260	COG1295	ribonuclease BN
CAI14_03270	COG1254	Belongs to the acylphosphatase family
CAI14_03300	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CAI14_03305	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CAI14_03315	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CAI14_03320	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CAI14_03330	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CAI14_03335	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CAI14_03340	COG0193	aminoacyl-tRNA hydrolase activity
CAI14_03345	COG0012	GTP binding
CAI14_03365	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CAI14_03380	COG0250	Participates in transcription elongation, termination and antitermination
CAI14_03385	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CAI14_03390	COG0081	regulation of translation
CAI14_03395	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CAI14_03400	COG0222	ribosome binding
CAI14_03405	COG0085	RNA polymerase activity
CAI14_03410	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CAI14_03415	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CAI14_03420	COG0049	tRNA binding
CAI14_03425	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CAI14_03430	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CAI14_03435	COG0051	transcription antitermination factor activity, RNA binding
CAI14_03440	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CAI14_03445	COG0088	Forms part of the polypeptide exit tunnel
CAI14_03450	COG0089	rRNA binding
CAI14_03455	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CAI14_03460	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CAI14_03470	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CAI14_03475	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CAI14_03480	COG0255	Belongs to the universal ribosomal protein uL29 family
CAI14_03485	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CAI14_03495	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CAI14_03500	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CAI14_03510	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CAI14_03515	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CAI14_03520	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CAI14_03530	COG1841	ribosomal large subunit assembly
CAI14_03535	COG0200	Binds to the 23S rRNA
CAI14_03540	COG0201	protein transport
CAI14_03565	COG0203	ribosomal protein L17
CAI14_03570	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CAI14_03590	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CAI14_03600	COG0154	amidase activity
CAI14_03615	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CAI14_03620	COG0039	L-malate dehydrogenase activity
CAI14_03630	COG0625	glutathione transferase activity
CAI14_03650	COG0446	pyridine nucleotide-disulphide oxidoreductase
CAI14_03650	COG1902	pentaerythritol trinitrate reductase activity
CAI14_03685	COG0156	8-amino-7-oxononanoate synthase activity
CAI14_03690	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CAI14_03695	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CAI14_03700	COG4208	sulfate ABC transporter
CAI14_03705	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CAI14_03715	COG1063	alcohol dehydrogenase
CAI14_03750	COG0406	alpha-ribazole phosphatase activity
CAI14_03760	COG0285	dihydrofolate synthase activity
CAI14_03780	COG2833	Protein of unknown function (DUF455)
CAI14_03800	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CAI14_03805	COG0671	phosphoesterase, PA-phosphatase related
CAI14_03810	COG0438	transferase activity, transferring glycosyl groups
CAI14_03820	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CAI14_03835	COG4783	chaperone-mediated protein folding
CAI14_03850	COG0473	3-isopropylmalate dehydrogenase activity
CAI14_03880	COG3852	Histidine kinase
CAI14_03890	COG0544	peptidyl-prolyl cis-trans isomerase activity
CAI14_03900	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CAI14_03925	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CAI14_03935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CAI14_03945	COG0328	RNA-DNA hybrid ribonuclease activity
CAI14_03950	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CAI14_03955	COG0631	protein serine/threonine phosphatase activity
CAI14_03970	COG0859	PFAM glycosyl transferase family 9
CAI14_03975	COG3642	lipopolysaccharide core region biosynthetic process
CAI14_03980	COG1234	tRNA 3'-trailer cleavage
CAI14_03985	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CAI14_03990	COG0315	cyclic pyranopterin monophosphate synthase activity
CAI14_03995	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CAI14_04000	COG0314	molybdopterin synthase activity
CAI14_04020	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CAI14_04025	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CAI14_04030	COG0537	adenosine 5'-monophosphoramidase activity
CAI14_04050	COG0714	Associated with various cellular activities
CAI14_04080	COG0424	maF-like protein
CAI14_04085	COG1399	metal-binding, possibly nucleic acid-binding protein
CAI14_04090	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CAI14_04095	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CAI14_04110	COG1028	Short-chain dehydrogenase reductase Sdr
CAI14_04125	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CAI14_04130	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CAI14_04155	COG3829	transcription factor binding
CAI14_04175	COG3609	addiction module antidote protein, CC2985 family
CAI14_04210	COG2373	Large extracellular alpha-helical protein
CAI14_04230	COG4953	penicillin-binding protein 1C
CAI14_04240	COG0678	peroxiredoxin activity
CAI14_04260	COG0330	HflC and HflK could
CAI14_04265	COG0330	HflC and HflK could
CAI14_04275	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CAI14_04280	COG0308	aminopeptidase N
CAI14_04285	COG1028	Short-chain dehydrogenase reductase Sdr
CAI14_04290	COG1309	transcriptional regulator
CAI14_04320	COG0732	type I restriction modification DNA specificity domain
CAI14_04345	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
CAI14_04385	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CAI14_04395	COG3387	PFAM Glycoside hydrolase 15-related
CAI14_04400	COG1028	Short-chain dehydrogenase reductase Sdr
CAI14_04410	COG3537	Alpha-1,2-mannosidase
CAI14_04415	COG1028	Short-chain dehydrogenase reductase Sdr
CAI14_04425	COG0492	ferredoxin-NADP+ reductase activity
CAI14_04485	COG2207	Transcriptional regulator
CAI14_04485	COG1917	Cupin 2, conserved barrel domain protein
CAI14_04510	COG0753	catalase activity
CAI14_04515	COG0656	L-ascorbic acid biosynthetic process
CAI14_04525	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CAI14_04525	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CAI14_04530	COG2814	Major facilitator Superfamily
CAI14_04545	COG2194	sulfuric ester hydrolase activity
CAI14_04560	COG0745	RESPONSE REGULATOR receiver
CAI14_04565	COG0642	Histidine kinase
CAI14_04575	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CAI14_04580	COG2894	cell division
CAI14_04585	COG0850	regulation of cytokinetic process
CAI14_04600	COG4585	Histidine kinase
CAI14_04605	COG2197	response regulator
CAI14_04620	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CAI14_04650	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CAI14_04660	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CAI14_04710	COG0824	Thioesterase
CAI14_04715	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CAI14_04720	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CAI14_04725	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CAI14_04730	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CAI14_04735	COG0268	Binds directly to 16S ribosomal RNA
CAI14_04745	COG0196	riboflavin kinase activity
CAI14_04750	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CAI14_04755	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CAI14_04760	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CAI14_04775	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CAI14_04780	COG1845	cytochrome c oxidase, subunit III
CAI14_04785	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CAI14_04800	COG3152	Membrane
CAI14_04810	COG2207	Transcriptional regulator
CAI14_04815	COG0326	Molecular chaperone. Has ATPase activity
CAI14_04825	COG1366	Belongs to the anti-sigma-factor antagonist family
CAI14_04830	COG1366	Belongs to the anti-sigma-factor antagonist family
CAI14_04835	COG2172	sigma factor antagonist activity
CAI14_04860	COG4771	TonB-dependent receptor
CAI14_04870	COG5507	3-demethylubiquinone-9 3-methyltransferase
CAI14_04875	COG2205	protein histidine kinase activity
CAI14_04885	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CAI14_04890	COG2205	protein histidine kinase activity
CAI14_04890	COG3850	Histidine kinase
CAI14_04890	COG4999	Histidine kinase
CAI14_04890	COG3437	response regulator, receiver
CAI14_04930	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CAI14_04935	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CAI14_04945	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CAI14_04950	COG0228	four-way junction DNA binding
CAI14_04955	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CAI14_04960	COG0336	Belongs to the RNA methyltransferase TrmD family
CAI14_04965	COG0335	large ribosomal subunit rRNA binding
CAI14_04970	COG0534	Mate efflux family protein
CAI14_04990	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CAI14_05000	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CAI14_05025	COG0489	protein tyrosine kinase activity
CAI14_05035	COG0717	Belongs to the dCTP deaminase family
CAI14_05240	COG3179	chitinase
CAI14_05285	COG4695	Portal protein
CAI14_05315	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CAI14_05330	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CAI14_05335	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CAI14_05355	COG0494	nUDIX hydrolase
CAI14_05360	COG0433	COG0433 Predicted ATPase
CAI14_05375	COG0688	phosphatidylethanolamine metabolic process
CAI14_05385	COG2890	protein-(glutamine-N5) methyltransferase activity
CAI14_05390	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CAI14_05395	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CAI14_05400	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CAI14_05420	COG0101	tRNA pseudouridine synthase activity
CAI14_05425	COG0135	phosphoribosylanthranilate isomerase activity
CAI14_05435	COG0133	tryptophan synthase activity
CAI14_05445	COG0159	tryptophan synthase activity
CAI14_05450	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CAI14_05455	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CAI14_05485	COG0300	oxidoreductase activity
CAI14_05490	COG0149	triose-phosphate isomerase activity
CAI14_05505	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CAI14_05510	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CAI14_05515	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CAI14_05520	COG0649	NAD binding
CAI14_05525	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CAI14_05530	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CAI14_05540	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CAI14_05545	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CAI14_05550	COG0839	Belongs to the complex I subunit 6 family
CAI14_05570	COG1007	ATP synthesis coupled electron transport
CAI14_05580	COG0779	Required for maturation of 30S ribosomal subunits
CAI14_05585	COG0195	Participates in both transcription termination and antitermination
CAI14_05590	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CAI14_05595	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CAI14_05600	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CAI14_05605	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CAI14_05610	COG1185	polyribonucleotide nucleotidyltransferase activity
CAI14_05645	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CAI14_05655	COG2095	MarC family integral membrane protein
CAI14_05670	COG1611	Belongs to the LOG family
CAI14_05725	COG0556	nucleotide-excision repair
CAI14_05745	COG3505	Type IV secretory pathway VirD4
CAI14_05765	COG2948	multi-organism process
CAI14_05815	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CAI14_05820	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CAI14_05835	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CAI14_05840	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CAI14_05840	COG0072	phenylalanine-tRNA ligase activity
CAI14_05890	COG0438	transferase activity, transferring glycosyl groups
CAI14_05895	COG0438	transferase activity, transferring glycosyl groups
CAI14_05905	COG0438	transferase activity, transferring glycosyl groups
CAI14_05930	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CAI14_05935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CAI14_05940	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CAI14_05960	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CAI14_05970	COG1960	acyl-CoA dehydrogenase activity
CAI14_05985	COG3040	lipid binding
CAI14_06030	COG0784	Response regulator, receiver
CAI14_06030	COG4191	Histidine kinase
CAI14_06035	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CAI14_06040	COG1194	a g-specific adenine glycosylase
CAI14_06050	COG0552	protein localization to endoplasmic reticulum
CAI14_06060	COG3938	Belongs to the proline racemase family
CAI14_06065	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CAI14_06080	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CAI14_06090	COG0006	proline dipeptidase activity
CAI14_06105	COG0531	amino acid
CAI14_06250	COG0726	polysaccharide deacetylase
CAI14_06250	COG1649	PFAM Uncharacterised BCR, COG1649
CAI14_06345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CAI14_06350	COG0124	histidyl-tRNA synthetase
CAI14_06360	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CAI14_06365	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CAI14_06370	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CAI14_06375	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CAI14_06375	COG0131	Imidazoleglycerol-phosphate dehydratase
CAI14_06380	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CAI14_06385	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CAI14_06390	COG0107	imidazoleglycerol-phosphate synthase activity
CAI14_06395	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CAI14_06395	COG0140	phosphoribosyl-ATP diphosphatase activity
CAI14_06410	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
CAI14_06415	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CAI14_06420	COG0235	Class ii aldolase
CAI14_06425	COG0531	amino acid
CAI14_06430	COG0531	amino acid
CAI14_06440	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CAI14_06445	COG0277	FAD linked oxidase domain protein
CAI14_06465	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CAI14_06515	COG2258	MOSC domain
CAI14_06520	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CAI14_06525	COG0505	Belongs to the CarA family
CAI14_06535	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CAI14_06540	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CAI14_06550	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CAI14_06600	COG3279	Response regulator of the LytR AlgR family
CAI14_06610	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CAI14_06620	COG2205	protein histidine kinase activity
CAI14_06620	COG2198	Histidine kinase
CAI14_06620	COG0784	Response regulator, receiver
CAI14_06625	COG1024	Enoyl-CoA hydratase
CAI14_06660	COG0318	PFAM AMP-dependent synthetase and ligase
CAI14_06690	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CAI14_06700	COG2201	protein-glutamate methylesterase activity
CAI14_06705	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CAI14_06715	COG0840	transmembrane signaling receptor activity
CAI14_06725	COG0835	chemotaxis
CAI14_06740	COG0840	transmembrane signaling receptor activity
CAI14_06745	COG0840	transmembrane signaling receptor activity
CAI14_06750	COG0840	transmembrane signaling receptor activity
CAI14_06755	COG0840	transmembrane signaling receptor activity
CAI14_06760	COG0840	transmembrane signaling receptor activity
CAI14_06770	COG0840	transmembrane signaling receptor activity
CAI14_06775	COG0840	transmembrane signaling receptor activity
CAI14_06785	COG0840	transmembrane signaling receptor activity
CAI14_06790	COG0840	transmembrane signaling receptor activity
CAI14_06805	COG0840	transmembrane signaling receptor activity
CAI14_06820	COG0840	transmembrane signaling receptor activity
CAI14_06825	COG0643	Histidine kinase
CAI14_06825	COG2198	Histidine kinase
CAI14_06830	COG0745	RESPONSE REGULATOR receiver
CAI14_06840	COG0835	chemotaxis
CAI14_06850	COG1360	Flagellar Motor Protein
CAI14_06855	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CAI14_06895	COG0641	radical SAM
CAI14_06905	COG0784	Response regulator, receiver
CAI14_06905	COG0643	Histidine kinase
CAI14_06905	COG2198	Histidine kinase
CAI14_06935	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CAI14_06960	COG5001	Diguanylate cyclase
CAI14_06960	COG3300	MHYT domain
CAI14_06965	COG1684	flagellar biosynthetic protein fliR
CAI14_07030	COG1677	Flagellar hook-basal body complex protein FliE
CAI14_07075	COG1028	Short-chain dehydrogenase reductase Sdr
CAI14_07080	COG1028	Short-chain dehydrogenase reductase Sdr
CAI14_07125	COG2201	protein-glutamate methylesterase activity
CAI14_07155	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CAI14_07160	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CAI14_07165	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CAI14_07175	COG3951	Flagellar rod assembly protein muramidase FlgJ
CAI14_07175	COG1705	Flagellar rod assembly protein muramidase FlgJ
CAI14_07180	COG1706	bacterial-type flagellum-dependent cell motility
CAI14_07185	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CAI14_07200	COG4787	bacterial-type flagellum-dependent cell motility
CAI14_07215	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CAI14_07220	COG1558	bacterial-type flagellum-dependent cell motility
CAI14_07230	COG0784	Response regulator, receiver
CAI14_07230	COG0835	chemotaxis
CAI14_07250	COG5002	protein histidine kinase activity
CAI14_07280	COG2915	High frequency lysogenization protein hflD homolog
CAI14_07285	COG0482	sulfurtransferase activity
CAI14_07300	COG0542	response to heat
CAI14_07310	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CAI14_07320	COG0492	ferredoxin-NADP+ reductase activity
CAI14_07325	COG1674	ftsk spoiiie
CAI14_07335	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CAI14_07345	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CAI14_07350	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CAI14_07360	COG0183	Belongs to the thiolase family
CAI14_07365	COG1024	Enoyl-CoA hydratase
CAI14_07365	COG1250	3-hydroxyacyl-CoA dehydrogenase
CAI14_07380	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CAI14_07390	COG1426	Protein conserved in bacteria
CAI14_07400	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CAI14_07405	COG1160	GTP binding
CAI14_07410	COG0303	'Molybdopterin
CAI14_07420	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CAI14_07460	COG0708	Exodeoxyribonuclease III
CAI14_07475	COG0746	molybdenum cofactor guanylyltransferase activity
CAI14_07485	COG1648	precorrin-2 dehydrogenase activity
CAI14_07485	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CAI14_07525	COG3685	Protein conserved in bacteria
CAI14_07555	COG4566	intracellular signal transduction
CAI14_07575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CAI14_07605	COG0477	Major facilitator Superfamily
CAI14_07615	COG0784	Response regulator, receiver
CAI14_07615	COG2205	protein histidine kinase activity
CAI14_07615	COG5002	protein histidine kinase activity
CAI14_07620	COG2733	membrane
CAI14_07645	COG2223	nitrite transmembrane transporter activity
CAI14_07650	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CAI14_07655	COG0243	molybdopterin cofactor binding
CAI14_07665	COG0477	Major facilitator Superfamily
CAI14_07670	COG2703	oxygen carrier activity
CAI14_07680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CAI14_07685	COG0174	glutamine synthetase
CAI14_07690	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CAI14_07705	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CAI14_07725	COG3842	ATPase activity
CAI14_07730	COG1176	ABC-type spermidine putrescine transport system, permease component I
CAI14_07735	COG1177	transmembrane transport
CAI14_07740	COG1012	belongs to the aldehyde dehydrogenase family
CAI14_07755	COG4535	Mg2 and Co2 transporter CorC
CAI14_07765	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CAI14_07775	COG1702	phosphate starvation-inducible protein PhoH
CAI14_07780	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CAI14_07795	COG0741	lytic transglycosylase activity
CAI14_07810	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CAI14_07815	COG2857	Cytochrome c1
CAI14_07820	COG0625	glutathione transferase activity
CAI14_07825	COG2969	positive regulation of protein catabolic process
CAI14_07845	COG1201	RNA secondary structure unwinding
CAI14_07850	COG2094	Belongs to the DNA glycosylase MPG family
CAI14_07855	COG0840	transmembrane signaling receptor activity
CAI14_07860	COG0835	chemotaxis
CAI14_07900	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CAI14_07915	COG1570	exodeoxyribonuclease VII activity
CAI14_07920	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CAI14_07925	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CAI14_07925	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CAI14_07930	COG0802	atpase or kinase
CAI14_07935	COG0860	N-Acetylmuramoyl-L-alanine amidase
CAI14_07940	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CAI14_07970	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CAI14_07980	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CAI14_08015	COG2081	HI0933 family
CAI14_08020	COG4681	YaeQ
CAI14_08030	COG0625	glutathione transferase activity
CAI14_08040	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CAI14_08045	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CAI14_08050	COG0513	Belongs to the DEAD box helicase family
CAI14_08075	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CAI14_08080	COG0483	inositol monophosphate 1-phosphatase activity
CAI14_08095	COG3300	MHYT domain
CAI14_08095	COG5001	Diguanylate cyclase
CAI14_08100	COG1509	lysine 2,3-aminomutase activity
CAI14_08105	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CAI14_08115	COG0402	S-adenosylhomocysteine deaminase activity
CAI14_08120	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CAI14_08190	COG4302	ethanolamine ammonia-lyase activity
CAI14_08220	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CAI14_08225	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CAI14_08240	COG2166	iron-sulfur cluster assembly
CAI14_08245	COG0215	cysteine-tRNA ligase activity
CAI14_08255	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CAI14_08260	COG0137	argininosuccinate synthase activity
CAI14_08270	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CAI14_08275	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CAI14_08285	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CAI14_08290	COG0165	Argininosuccinate lyase
CAI14_08300	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CAI14_08305	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CAI14_08330	COG3344	reverse transcriptase
CAI14_08340	COG1294	oxidase, subunit
CAI14_08350	COG4988	ABC transporter
CAI14_08355	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CAI14_08360	COG1278	Cold shock
CAI14_08365	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CAI14_08385	COG1138	Cytochrome C-type biogenesis protein
CAI14_08390	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CAI14_08410	COG4133	protoheme IX ABC transporter activity
CAI14_08415	COG0436	Aminotransferase
CAI14_08435	COG1187	pseudouridine synthase activity
CAI14_08440	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CAI14_08445	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CAI14_08450	COG2350	Protein conserved in bacteria
CAI14_08480	COG1175	transmembrane transport
CAI14_08485	COG0395	ABC-type sugar transport system, permease component
CAI14_08510	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CAI14_08515	COG2957	Belongs to the agmatine deiminase family
CAI14_08535	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CAI14_08540	COG0539	negative regulation of cytoplasmic translation
CAI14_08545	COG0776	regulation of translation
CAI14_08555	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CAI14_08560	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CAI14_08570	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CAI14_08580	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CAI14_08580	COG0475	glutathione-regulated potassium exporter activity
CAI14_08590	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CAI14_08600	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CAI14_08600	COG0519	Catalyzes the synthesis of GMP from XMP
CAI14_08605	COG3002	Belongs to the UPF0753 family
CAI14_08610	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CAI14_08615	COG0583	DNA-binding transcription factor activity
CAI14_08635	COG2197	response regulator
CAI14_08650	COG1335	isochorismatase
CAI14_08675	COG2814	Major facilitator Superfamily
CAI14_08695	COG1914	H( )-stimulated, divalent metal cation uptake system
CAI14_08710	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CAI14_08740	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CAI14_08825	COG4456	Virulence-associated protein
CAI14_08850	COG0668	transmembrane transport
CAI14_08860	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CAI14_08875	COG1028	Short-chain dehydrogenase reductase Sdr
CAI14_08880	COG1183	phosphatidylcholine synthase activity
CAI14_08890	COG3243	poly(R)-hydroxyalkanoic acid synthase
CAI14_08905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CAI14_08905	COG0723	plastoquinol--plastocyanin reductase activity
CAI14_08915	COG2183	response to ionizing radiation
CAI14_08920	COG0784	Response regulator, receiver
CAI14_08920	COG2205	protein histidine kinase activity
CAI14_08995	COG0800	Aldolase
CAI14_09000	COG0129	dihydroxy-acid dehydratase activity
CAI14_09005	COG0363	glucosamine-6-phosphate deaminase activity
CAI14_09010	COG0837	glucose binding
CAI14_09015	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CAI14_09040	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CAI14_09060	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CAI14_09070	COG4591	ABC-type transport system involved in lipoprotein release permease component
CAI14_09075	COG1136	(ABC) transporter
CAI14_09090	COG0811	peptide transport
CAI14_09100	COG1132	(ABC) transporter
CAI14_09105	COG1663	tetraacyldisaccharide 4'-kinase activity
CAI14_09110	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CAI14_09115	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CAI14_09125	COG0322	excinuclease ABC activity
CAI14_09130	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CAI14_09210	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CAI14_09235	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CAI14_09265	COG1530	ribonuclease E activity
CAI14_09275	COG3064	Membrane
CAI14_09280	COG0428	transporter
CAI14_09290	COG2154	pterin-4-alpha-carbinolamine dehydratase
CAI14_09295	COG0316	Belongs to the HesB IscA family
CAI14_09295	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CAI14_09385	COG1073	alpha beta
CAI14_09385	COG2226	methyltransferase
CAI14_09420	COG1028	Short-chain dehydrogenase reductase Sdr
CAI14_09440	COG1238	metal cluster binding
CAI14_09475	COG2902	Dehydrogenase
CAI14_09485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CAI14_09490	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CAI14_09500	COG1609	Transcriptional regulator
CAI14_09505	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CAI14_09505	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CAI14_09510	COG1105	Belongs to the carbohydrate kinase PfkB family
CAI14_09515	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CAI14_09515	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CAI14_09560	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CAI14_09570	COG1862	Preprotein translocase
CAI14_09575	COG0343	queuine tRNA-ribosyltransferase activity
CAI14_09580	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CAI14_09620	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CAI14_09625	COG3291	Pkd domain containing protein
CAI14_09630	COG0405	Gamma-glutamyltransferase
CAI14_09635	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CAI14_09650	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CAI14_09655	COG0742	ribosomal rna small subunit methyltransferase
CAI14_09660	COG0326	Molecular chaperone. Has ATPase activity
CAI14_09690	COG1012	belongs to the aldehyde dehydrogenase family
CAI14_09710	COG0167	dihydroorotate dehydrogenase activity
CAI14_09715	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CAI14_09745	COG0671	phosphoesterase, PA-phosphatase related
CAI14_09765	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CAI14_09770	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CAI14_09780	COG2203	Gaf domain
CAI14_09780	COG3706	GGDEF domain
CAI14_09780	COG4251	negative regulation of phosphorylation
CAI14_09780	COG5001	Diguanylate cyclase
CAI14_09795	COG1472	Belongs to the glycosyl hydrolase 3 family
CAI14_09825	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CAI14_09830	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CAI14_09835	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CAI14_09855	COG1469	GTP cyclohydrolase I activity
CAI14_09860	COG0860	N-Acetylmuramoyl-L-alanine amidase
CAI14_09880	COG0477	Major facilitator Superfamily
CAI14_09885	COG2115	Belongs to the xylose isomerase family
CAI14_09890	COG1070	Carbohydrate kinase
CAI14_09900	COG1501	Belongs to the glycosyl hydrolase 31 family
CAI14_09940	COG0800	Aldolase
CAI14_09945	COG4948	Mandelate Racemase Muconate Lactonizing
CAI14_09955	COG3734	2-keto-3-deoxy-galactonokinase
CAI14_09960	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CAI14_09970	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CAI14_09985	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CAI14_09990	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CAI14_10005	COG0351	phosphomethylpyrimidine kinase
CAI14_10030	COG0583	DNA-binding transcription factor activity
CAI14_10035	COG1741	Belongs to the pirin family
CAI14_10055	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CAI14_10060	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CAI14_10065	COG2137	regulation of response to DNA damage stimulus
CAI14_10075	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CAI14_10080	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CAI14_10090	COG1546	Belongs to the CinA family
CAI14_10095	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CAI14_10105	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CAI14_10110	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CAI14_10120	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CAI14_10125	COG1534	Rna-binding protein
CAI14_10140	COG1238	metal cluster binding
CAI14_10145	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CAI14_10150	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CAI14_10155	COG2840	Smr protein MutS2
CAI14_10160	COG0585	pseudouridine synthase activity
CAI14_10165	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CAI14_10170	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CAI14_10175	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CAI14_10180	COG0148	phosphopyruvate hydratase activity
CAI14_10190	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CAI14_10195	COG0504	CTP synthase activity
CAI14_10220	COG0306	phosphate transporter
CAI14_10235	COG1253	flavin adenine dinucleotide binding
CAI14_10250	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CAI14_10255	COG0477	Major facilitator Superfamily
CAI14_10260	COG1132	(ABC) transporter
CAI14_10265	COG1136	(ABC) transporter
CAI14_10290	COG2264	protein methyltransferase activity
CAI14_10325	COG2244	polysaccharide biosynthetic process
CAI14_10380	COG1595	DNA-templated transcription, initiation
CAI14_10395	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CAI14_10405	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CAI14_10415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CAI14_10430	COG4191	Histidine kinase
CAI14_10430	COG0784	Response regulator, receiver
CAI14_10435	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
CAI14_10470	COG0840	transmembrane signaling receptor activity
CAI14_10495	COG0583	DNA-binding transcription factor activity
CAI14_10500	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CAI14_10505	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CAI14_10520	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CAI14_10525	COG1605	Chorismate mutase
CAI14_10525	COG0077	Prephenate dehydratase
CAI14_10530	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CAI14_10535	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CAI14_10540	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CAI14_10580	COG1228	amidohydrolase
CAI14_10585	COG2986	histidine ammonia-lyase
CAI14_10595	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CAI14_10610	COG4993	Dehydrogenase
CAI14_10620	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CAI14_10635	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CAI14_10640	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CAI14_10645	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CAI14_10655	COG3115	cell septum assembly
CAI14_10665	COG0359	binds to the 23S rRNA
CAI14_10670	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CAI14_10675	COG0360	Binds together with S18 to 16S ribosomal RNA
CAI14_10680	COG0316	Belongs to the HesB IscA family
CAI14_10690	COG0017	Asparaginyl-tRNA synthetase
CAI14_10710	COG2808	Putative FMN-binding domain
CAI14_10775	COG0288	reversible hydration of carbon dioxide
CAI14_10780	COG0662	Cupin 2, conserved barrel domain protein
CAI14_10790	COG3844	kynureninase activity
CAI14_10795	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CAI14_10805	COG2925	Exonuclease
CAI14_10830	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CAI14_10835	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CAI14_10835	COG0116	Belongs to the methyltransferase superfamily
CAI14_10880	COG0494	nUDIX hydrolase
CAI14_10890	COG1024	Enoyl-CoA hydratase
CAI14_10900	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CAI14_10905	COG0659	secondary active sulfate transmembrane transporter activity
CAI14_10930	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CAI14_10935	COG0573	inorganic phosphate transmembrane transporter activity
CAI14_10940	COG0581	inorganic phosphate transmembrane transporter activity
CAI14_10945	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CAI14_10950	COG0704	Plays a role in the regulation of phosphate uptake
CAI14_10960	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CAI14_10965	COG3706	GGDEF domain
CAI14_10970	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CAI14_10980	COG0557	exoribonuclease II activity
CAI14_11000	COG1960	acyl-CoA dehydrogenase activity
CAI14_11005	COG1960	acyl-CoA dehydrogenase activity
CAI14_11010	COG2226	methyltransferase
CAI14_11015	COG0646	methionine synthase
CAI14_11015	COG1410	methionine synthase
CAI14_11040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CAI14_11065	COG2900	Belongs to the SlyX family
CAI14_11080	COG0386	Belongs to the glutathione peroxidase family
CAI14_11090	COG1725	Transcriptional regulator
CAI14_11095	COG1131	(ABC) transporter
CAI14_11125	COG1253	flavin adenine dinucleotide binding
CAI14_11180	COG1132	(ABC) transporter
CAI14_11185	COG0583	DNA-binding transcription factor activity
CAI14_11225	COG0484	heat shock protein binding
CAI14_11230	COG0443	Heat shock 70 kDa protein
CAI14_11235	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CAI14_11240	COG1420	regulation of RNA biosynthetic process
CAI14_11245	COG0497	DNA recombination
CAI14_11255	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CAI14_11270	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CAI14_11300	COG3706	GGDEF domain
CAI14_11310	COG3706	GGDEF domain
CAI14_11350	COG0583	DNA-binding transcription factor activity
CAI14_11370	COG0415	Belongs to the DNA photolyase family
CAI14_11375	COG0305	Participates in initiation and elongation during chromosome replication
CAI14_11385	COG0367	asparagine synthase
CAI14_11405	COG1960	acyl-CoA dehydrogenase activity
CAI14_11420	COG0084	hydrolase, TatD family'
CAI14_11425	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CAI14_11485	COG0386	Belongs to the glutathione peroxidase family
CAI14_11495	COG0339	signal peptide processing
CAI14_11525	COG3104	oligopeptide transport
CAI14_11550	COG2814	Major facilitator Superfamily
CAI14_11555	COG1566	PFAM secretion protein HlyD family protein
CAI14_11600	COG4774	siderophore transport
CAI14_11610	COG0367	asparagine synthase
CAI14_11615	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CAI14_11620	COG1393	Belongs to the ArsC family
CAI14_11630	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CAI14_11670	COG0052	Belongs to the universal ribosomal protein uS2 family
CAI14_11675	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CAI14_11685	COG0528	UMP kinase activity
CAI14_11690	COG0233	cytoplasmic translational termination
CAI14_11695	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CAI14_11700	COG0575	Belongs to the CDS family
CAI14_11705	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CAI14_11710	COG0750	zinc metalloprotease
CAI14_11725	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CAI14_11730	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CAI14_11735	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CAI14_11740	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CAI14_11745	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CAI14_11755	COG0825	malonyl-CoA metabolic process
CAI14_11790	COG1695	Transcriptional regulator
CAI14_11810	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CAI14_11820	COG2040	homocysteine
CAI14_11825	COG0833	amino acid
CAI14_11830	COG0346	lactoylglutathione lyase activity
CAI14_11835	COG1131	(ABC) transporter
CAI14_11850	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CAI14_11850	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CAI14_11860	COG2878	Part of a membrane complex involved in electron transport
CAI14_11880	COG1595	DNA-templated transcription, initiation
CAI14_11905	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CAI14_11920	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CAI14_11925	COG0251	oxidation-reduction process
CAI14_11935	COG0392	lysyltransferase activity
CAI14_11935	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CAI14_11965	COG2814	Major facilitator Superfamily
CAI14_11980	COG2824	Alkylphosphonate utilization operon protein PhnA
CAI14_11990	COG1047	Peptidyl-prolyl cis-trans
CAI14_12010	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CAI14_12020	COG5487	UPF0391 membrane protein
CAI14_12025	COG1451	nucleotide metabolic process
CAI14_12050	COG0183	Belongs to the thiolase family
CAI14_12080	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CAI14_12080	COG1793	dna ligase
CAI14_12090	COG1793	dna ligase
CAI14_12095	COG1201	RNA secondary structure unwinding
CAI14_12110	COG1278	Cold shock
CAI14_12120	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CAI14_12130	COG1472	Belongs to the glycosyl hydrolase 3 family
CAI14_12135	COG3046	protein related to deoxyribodipyrimidine photolyase
CAI14_12140	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
CAI14_12145	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CAI14_12150	COG2954	triphosphatase activity
CAI14_12160	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CAI14_12170	COG1381	Involved in DNA repair and RecF pathway recombination
CAI14_12175	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CAI14_12180	COG0571	ribonuclease III activity
CAI14_12195	COG0481	GTPase activity
CAI14_12200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CAI14_12235	COG1024	Enoyl-CoA hydratase
CAI14_12240	COG1960	acyl-CoA dehydrogenase activity
CAI14_12260	COG3867	Arabinogalactan endo-beta-1,4-galactanase
CAI14_12265	COG3250	beta-galactosidase activity
CAI14_12310	COG3209	COG3209 Rhs family protein
CAI14_12315	COG3209	COG3209 Rhs family protein
CAI14_12370	COG3590	peptidase
CAI14_12380	COG3590	peptidase
CAI14_12405	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CAI14_12410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CAI14_12415	COG2311	Membrane
CAI14_12420	COG1047	Peptidyl-prolyl cis-trans
CAI14_12425	COG0791	NLP P60 protein
CAI14_12430	COG0791	NLP P60 protein
CAI14_12440	COG4106	trans-aconitate 2-methyltransferase activity
CAI14_12445	COG1301	dicarboxylic acid transport
CAI14_12450	COG1785	Belongs to the alkaline phosphatase family
CAI14_12460	COG0037	tRNA processing
CAI14_12465	COG1722	exodeoxyribonuclease VII activity
CAI14_12470	COG0142	geranyltranstransferase activity
CAI14_12515	COG0312	modulator of DNA gyrase
CAI14_12520	COG3028	Belongs to the UPF0307 family
CAI14_12525	COG0312	modulator of DNA gyrase
CAI14_12535	COG3164	Protein of unknown function
CAI14_12540	COG1530	ribonuclease E activity
CAI14_12545	COG0424	maF-like protein
CAI14_12550	COG2968	Membrane
CAI14_12570	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CAI14_12585	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CAI14_12600	COG0495	leucyl-tRNA aminoacylation
CAI14_12610	COG3118	belongs to the thioredoxin family
CAI14_12650	COG2155	Conserved Protein
CAI14_12695	COG1132	(ABC) transporter
CAI14_12725	COG1538	Outer membrane efflux protein
CAI14_12730	COG0745	RESPONSE REGULATOR receiver
CAI14_12735	COG5002	protein histidine kinase activity
CAI14_12735	COG5000	phosphorelay sensor kinase activity
CAI14_12740	COG0475	glutathione-regulated potassium exporter activity
CAI14_12750	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CAI14_12775	COG1187	pseudouridine synthase activity
CAI14_12780	COG5001	Diguanylate cyclase
CAI14_12780	COG5002	protein histidine kinase activity
CAI14_12830	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CAI14_12915	COG2814	Major facilitator Superfamily
CAI14_12950	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CAI14_12965	COG0735	belongs to the Fur family
CAI14_12970	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CAI14_12995	COG4452	Inner membrane protein CreD
CAI14_13005	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CAI14_13020	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CAI14_13030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CAI14_13045	COG2198	Histidine kinase
CAI14_13045	COG0643	Histidine kinase
CAI14_13050	COG0840	transmembrane signaling receptor activity
CAI14_13055	COG0835	chemotaxis
CAI14_13060	COG2199	diguanylate cyclase activity
CAI14_13060	COG2200	EAL domain
CAI14_13060	COG2202	Pas domain
CAI14_13065	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CAI14_13070	COG2201	protein-glutamate methylesterase activity
CAI14_13075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CAI14_13090	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CAI14_13125	COG4181	ATPase activity
CAI14_13135	COG2175	clavaminate synthase activity
CAI14_13145	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CAI14_13150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CAI14_13170	COG4771	TonB-dependent receptor
CAI14_13180	COG0667	Aldo Keto reductase
CAI14_13190	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CAI14_13195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CAI14_13205	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CAI14_13210	COG4106	trans-aconitate 2-methyltransferase activity
CAI14_13220	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CAI14_13270	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CAI14_13280	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CAI14_13285	COG2226	methyltransferase
CAI14_13320	COG0366	Alpha amylase catalytic
CAI14_13350	COG0604	alcohol dehydrogenase
CAI14_13350	COG1028	Short-chain dehydrogenase reductase Sdr
CAI14_13350	COG3321	synthase
CAI14_13365	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CAI14_13375	COG0494	nUDIX hydrolase
CAI14_13380	COG0653	protein targeting
CAI14_13395	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CAI14_13410	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CAI14_13415	COG1181	Belongs to the D-alanine--D-alanine ligase family
CAI14_13420	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CAI14_13425	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CAI14_13435	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CAI14_13440	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CAI14_13445	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CAI14_13455	COG3116	cell division
CAI14_13460	COG0275	rRNA processing
CAI14_13500	COG0792	nuclease activity
CAI14_13505	COG1988	membrane-bound metal-dependent
CAI14_13510	COG0277	FAD linked oxidase domain protein
CAI14_13540	COG0745	RESPONSE REGULATOR receiver
CAI14_13545	COG2205	protein histidine kinase activity
CAI14_13550	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CAI14_13555	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CAI14_13560	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CAI14_13585	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CAI14_13590	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CAI14_13595	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CAI14_13615	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CAI14_13615	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CAI14_13625	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CAI14_13630	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CAI14_13640	COG0488	(ABC) transporter
CAI14_13650	COG0697	spore germination
CAI14_13660	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CAI14_13675	COG3791	Glutathione-dependent formaldehyde-activating
CAI14_13700	COG0745	RESPONSE REGULATOR receiver
CAI14_13705	COG2205	protein histidine kinase activity
CAI14_13725	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CAI14_13730	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CAI14_13760	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CAI14_13765	COG1012	belongs to the aldehyde dehydrogenase family
CAI14_13770	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CAI14_13775	COG0617	tRNA 3'-terminal CCA addition
CAI14_13785	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CAI14_13790	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CAI14_13795	COG1609	Transcriptional regulator
CAI14_13805	COG2188	Transcriptional regulator
CAI14_13820	COG3250	beta-galactosidase activity
CAI14_13850	COG4795	General secretion pathway protein
CAI14_13870	COG1459	type II secretion system
CAI14_13930	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CAI14_13935	COG4191	Histidine kinase
CAI14_13940	COG0784	Response regulator, receiver
CAI14_13945	COG4251	negative regulation of phosphorylation
CAI14_13950	COG2823	Periplasmic or secreted lipoprotein
CAI14_13955	COG0673	inositol 2-dehydrogenase activity
CAI14_13960	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CAI14_13995	COG1051	belongs to the nudix hydrolase family
CAI14_13995	COG1056	cytidyltransferase-related domain
CAI14_14005	COG0583	DNA-binding transcription factor activity
CAI14_14020	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CAI14_14025	COG0321	lipoyl(octanoyl) transferase activity
CAI14_14030	COG2921	Belongs to the UPF0250 family
CAI14_14040	COG1686	Belongs to the peptidase S11 family
CAI14_14050	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CAI14_14055	COG2951	lytic endotransglycosylase activity
CAI14_14065	COG0772	Belongs to the SEDS family
CAI14_14080	COG1792	Involved in formation and maintenance of cell shape
CAI14_14085	COG1077	Cell shape determining protein MreB Mrl
CAI14_14090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CAI14_14095	COG3284	Transcriptional regulator
CAI14_14115	COG2010	Cytochrome c
CAI14_14210	COG5002	protein histidine kinase activity
CAI14_14215	COG0745	RESPONSE REGULATOR receiver
CAI14_14225	COG0189	ligase activity
CAI14_14270	COG2022	thiamine diphosphate biosynthetic process
CAI14_14280	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CAI14_14285	COG0471	metal ion transport
CAI14_14285	COG3273	potassium ion transport
CAI14_14310	COG1970	mechanosensitive ion channel activity
CAI14_14320	COG1609	Transcriptional regulator
CAI14_14330	COG3250	beta-galactosidase activity
CAI14_14335	COG4948	Mandelate Racemase Muconate Lactonizing
CAI14_14350	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CAI14_14400	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CAI14_14405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CAI14_14410	COG0529	Catalyzes the synthesis of activated sulfate
CAI14_14410	COG2895	sulfate adenylyltransferase (ATP) activity
CAI14_14415	COG0175	sulfate reduction
CAI14_14420	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CAI14_14425	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CAI14_14430	COG0175	sulfate reduction
CAI14_14450	COG2198	Histidine kinase
CAI14_14450	COG0784	Response regulator, receiver
CAI14_14450	COG2205	protein histidine kinase activity
CAI14_14470	COG1648	precorrin-2 dehydrogenase activity
CAI14_14470	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CAI14_14485	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CAI14_14490	COG3588	fructose-bisphosphate aldolase
CAI14_14495	COG0469	pyruvate kinase activity
CAI14_14505	COG0126	phosphoglycerate kinase activity
CAI14_14530	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CAI14_14545	COG3047	cAMP biosynthetic process
CAI14_14550	COG3047	cAMP biosynthetic process
CAI14_14560	COG3453	Protein conserved in bacteria
CAI14_14560	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CAI14_14565	COG0725	ABC transporter, periplasmic molybdate-binding protein
CAI14_14570	COG4149	molybdate abc transporter
CAI14_14575	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CAI14_14610	COG1376	ErfK ybiS ycfS ynhG family protein
CAI14_14620	COG0739	heme binding
CAI14_14630	COG4773	Receptor
CAI14_14635	COG0596	Alpha beta hydrolase
CAI14_14640	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CAI14_14645	COG1301	dicarboxylic acid transport
CAI14_14660	COG2304	oxidoreductase activity
CAI14_14680	COG0714	Associated with various cellular activities
CAI14_14710	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CAI14_14740	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CAI14_14750	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CAI14_14755	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CAI14_14760	COG2390	Transcriptional regulator
CAI14_14775	COG3659	wide pore channel activity
CAI14_14795	COG1028	Short-chain dehydrogenase reductase Sdr
CAI14_14800	COG1070	Carbohydrate kinase
CAI14_14810	COG0194	GDP metabolic process
CAI14_14815	COG1561	YicC-like family, N-terminal region
CAI14_14820	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CAI14_14830	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CAI14_14835	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CAI14_14850	COG0006	proline dipeptidase activity
CAI14_14860	COG0006	proline dipeptidase activity
CAI14_14865	COG3079	Belongs to the UPF0149 family
CAI14_14885	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CAI14_14895	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CAI14_14905	COG2912	Transglutaminase-like superfamily
CAI14_14910	COG1773	rubredoxin
CAI14_14915	COG0352	thiamine-phosphate diphosphorylase activity
CAI14_14930	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CAI14_14945	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CAI14_14975	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CAI14_14980	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CAI14_14990	COG1028	Short-chain dehydrogenase reductase Sdr
CAI14_15000	COG0671	phosphoesterase, PA-phosphatase related
CAI14_15005	COG3781	membrane
CAI14_15015	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CAI14_15020	COG0563	adenylate kinase activity
CAI14_15045	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CAI14_15055	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CAI14_15085	COG3710	Transcriptional regulator
CAI14_15090	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CAI14_15105	COG0840	transmembrane signaling receptor activity
CAI14_15115	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CAI14_15135	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CAI14_15140	COG0473	3-isopropylmalate dehydrogenase activity
CAI14_15145	COG0066	3-isopropylmalate dehydratase activity
CAI14_15150	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CAI14_15170	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CAI14_15175	COG1538	Outer membrane efflux protein
CAI14_15180	COG1519	Transferase
CAI14_15185	COG1560	Kdo2-lipid A biosynthetic process
CAI14_15210	COG0281	malic enzyme
CAI14_15210	COG0280	phosphate acetyltransferase
CAI14_15215	COG1301	dicarboxylic acid transport
CAI14_15245	COG0583	DNA-binding transcription factor activity
CAI14_15255	COG0667	Aldo Keto reductase
CAI14_15275	COG2197	response regulator
CAI14_15290	COG0642	Histidine kinase
CAI14_15310	COG2851	Citrate transporter
CAI14_15315	COG1028	Short-chain dehydrogenase reductase Sdr
CAI14_15320	COG1609	Transcriptional regulator
CAI14_15350	COG1162	GTPase activity
CAI14_15385	COG0308	aminopeptidase N
CAI14_15390	COG2199	diguanylate cyclase activity
CAI14_15395	COG2226	methyltransferase
CAI14_15420	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CAI14_15425	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CAI14_15430	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CAI14_15440	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CAI14_15450	COG2832	Protein of unknown function (DUF454)
CAI14_15470	COG1505	serine-type exopeptidase activity
CAI14_15510	COG0181	hydroxymethylbilane synthase activity
CAI14_15520	COG3275	phosphorelay sensor kinase activity
CAI14_15530	COG2943	transferase activity, transferring hexosyl groups
CAI14_15550	COG3706	GGDEF domain
CAI14_15560	COG0659	secondary active sulfate transmembrane transporter activity
CAI14_15565	COG5297	Belongs to the glycosyl hydrolase family 6
CAI14_15565	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CAI14_15570	COG0840	transmembrane signaling receptor activity
CAI14_15580	COG5001	Diguanylate cyclase
CAI14_15630	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
CAI14_15650	COG1113	amino acid transport
CAI14_15665	COG0697	spore germination
CAI14_15690	COG3706	GGDEF domain
CAI14_15710	COG0823	Involved in the tonB-independent uptake of proteins
CAI14_15710	COG1506	peptidase
CAI14_15720	COG2409	Drug exporters of the RND superfamily
CAI14_15745	COG0435	Glutathione S-transferase
CAI14_15760	COG4221	oxidoreductase activity
CAI14_15775	COG4221	oxidoreductase activity
CAI14_15850	COG1802	Transcriptional regulator
CAI14_15885	COG3052	prosthetic group binding
CAI14_15915	COG2353	YceI-like domain
CAI14_15920	COG0778	Nitroreductase
CAI14_15940	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CAI14_15945	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CAI14_15955	COG3386	PFAM SMP-30 Gluconolaconase
CAI14_15970	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CAI14_15985	COG0459	protein refolding
CAI14_15995	COG2356	endonuclease I
CAI14_16005	COG0300	oxidoreductase activity
CAI14_16035	COG1324	tolerance protein
CAI14_16045	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CAI14_16050	COG0511	ligase activity, forming carbon-carbon bonds
CAI14_16060	COG0439	Biotin carboxylase
CAI14_16080	COG2264	protein methyltransferase activity
CAI14_16105	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CAI14_16110	COG4589	Belongs to the CDS family
CAI14_16135	COG2453	phosphatase
CAI14_16135	COG0671	phosphoesterase, PA-phosphatase related
CAI14_16140	COG2267	carboxylic ester hydrolase activity
CAI14_16145	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CAI14_16150	COG0138	bifunctional purine biosynthesis protein purh
CAI14_16160	COG0151	Belongs to the GarS family
CAI14_16170	COG1289	transmembrane transporter activity
CAI14_16175	COG2814	Major facilitator Superfamily
CAI14_16185	COG2814	Major facilitator Superfamily
CAI14_16205	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CAI14_16225	COG0316	Belongs to the HesB IscA family
CAI14_16265	COG1051	belongs to the nudix hydrolase family
CAI14_16280	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CAI14_16290	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
CAI14_16300	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CAI14_16305	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CAI14_16315	COG0134	indole-3-glycerol-phosphate synthase activity
CAI14_16320	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CAI14_16345	COG1597	lipid kinase activity
CAI14_16350	COG0456	acetyltransferase
CAI14_16365	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CAI14_16370	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CAI14_16390	COG3179	chitinase
CAI14_16415	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CAI14_16415	COG2111	Na H antiporter
CAI14_16420	COG1006	Multisubunit Na H antiporter MnhC subunit
CAI14_16425	COG0651	ATP synthesis coupled electron transport
CAI14_16435	COG2212	antiporter activity
CAI14_16440	COG1320	monovalent cation:proton antiporter activity
CAI14_16460	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CAI14_16485	COG3104	oligopeptide transport
CAI14_16490	COG3483	tryptophan 2,3-dioxygenase activity
CAI14_16505	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CAI14_16525	COG0513	Belongs to the DEAD box helicase family
CAI14_16540	COG1028	Short-chain dehydrogenase reductase Sdr
CAI14_16545	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CAI14_16580	COG1028	Short-chain dehydrogenase reductase Sdr
CAI14_16585	COG0702	epimerase
CAI14_16610	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CAI14_16615	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CAI14_16620	COG0297	glycogen (starch) synthase activity
CAI14_16630	COG2354	Protein conserved in bacteria
CAI14_16635	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CAI14_16645	COG1368	sulfuric ester hydrolase activity
CAI14_16650	COG3264	Mechanosensitive ion channel
CAI14_16650	COG1511	domain protein
CAI14_16720	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CAI14_16810	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CAI14_16815	COG1040	competence protein
CAI14_16820	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CAI14_16825	COG0156	8-amino-7-oxononanoate synthase activity
CAI14_16835	COG2267	carboxylic ester hydrolase activity
CAI14_16875	COG0445	tRNA wobble uridine modification
CAI14_16895	COG1414	Transcriptional regulator
CAI14_16905	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CAI14_16910	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CAI14_16925	COG3485	protocatechuate 3,4-dioxygenase
CAI14_16935	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CAI14_16940	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CAI14_16970	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CAI14_16975	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CAI14_17035	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CAI14_17050	COG0129	dihydroxy-acid dehydratase activity
CAI14_17095	COG1733	regulation of RNA biosynthetic process
CAI14_17100	COG0702	epimerase
CAI14_17135	COG0583	DNA-binding transcription factor activity
CAI14_17140	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CAI14_17165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CAI14_17170	COG2205	protein histidine kinase activity
CAI14_17175	COG0745	RESPONSE REGULATOR receiver
CAI14_17195	COG1902	pentaerythritol trinitrate reductase activity
CAI14_17200	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CAI14_17215	COG2814	Major facilitator Superfamily
CAI14_17220	COG0583	DNA-binding transcription factor activity
CAI14_17240	COG0084	hydrolase, TatD family'
CAI14_17265	COG2252	PERMEase
CAI14_17275	COG1957	nucleoside hydrolase
CAI14_17310	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CAI14_17330	COG2072	flavoprotein involved in K transport
CAI14_17335	COG2351	hydroxyisourate hydrolase activity
CAI14_17340	COG4807	Protein conserved in bacteria
CAI14_17345	COG1643	Atp-dependent helicase
CAI14_17360	COG1187	pseudouridine synthase activity
CAI14_17375	COG2130	NADP-dependent
CAI14_17405	COG1764	response to oxidative stress
CAI14_17410	COG1846	Transcriptional regulator
CAI14_17415	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CAI14_17435	COG0523	cobalamin synthesis protein
CAI14_17490	COG1309	transcriptional regulator
CAI14_17495	COG1960	acyl-CoA dehydrogenase activity
CAI14_17500	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CAI14_17505	COG4770	biotin carboxylase activity
CAI14_17540	COG3706	GGDEF domain
CAI14_17545	COG2224	Isocitrate lyase
CAI14_17550	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CAI14_17555	COG0583	DNA-binding transcription factor activity
CAI14_17560	COG0475	glutathione-regulated potassium exporter activity
CAI14_17590	COG0339	signal peptide processing
CAI14_17595	COG1446	asparaginase
CAI14_17615	COG0564	pseudouridine synthase activity
CAI14_17625	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CAI14_17650	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CAI14_17655	COG0318	PFAM AMP-dependent synthetase and ligase
CAI14_17660	COG0727	PFAM Uncharacterised protein family (UPF0153)
CAI14_17665	COG0596	Alpha beta hydrolase
CAI14_17675	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CAI14_17690	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CAI14_17715	COG2205	protein histidine kinase activity
CAI14_17720	COG0028	Belongs to the TPP enzyme family
CAI14_17755	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CAI14_17780	COG1157	protein secretion by the type III secretion system
CAI14_17795	COG1766	The M ring may be actively involved in energy transduction
CAI14_17800	COG1677	Flagellar hook-basal body complex protein FliE
CAI14_17815	COG1706	bacterial-type flagellum-dependent cell motility
CAI14_17830	COG4786	Flagellar basal body rod
CAI14_17835	COG4786	Flagellar basal body rod
CAI14_17840	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CAI14_17845	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CAI14_17900	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CAI14_17905	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CAI14_17910	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CAI14_17945	COG0183	Belongs to the thiolase family
CAI14_17960	COG2032	superoxide dismutase activity
CAI14_17965	COG2032	superoxide dismutase activity
CAI14_17970	COG2204	response regulator
CAI14_17975	COG3852	Histidine kinase
CAI14_17980	COG0004	ammonium transporteR
CAI14_17985	COG0347	Belongs to the P(II) protein family
CAI14_17990	COG0174	glutamine synthetase
CAI14_18000	COG1968	undecaprenyl-diphosphatase activity
CAI14_18045	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CAI14_18055	COG2062	phosphohistidine phosphatase, SixA
CAI14_18060	COG0489	protein tyrosine kinase activity
CAI14_18115	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CAI14_18130	COG1125	glycine betaine transport
CAI14_18145	COG1119	ATPase activity
CAI14_18155	COG1752	Esterase of the alpha-beta hydrolase superfamily
CAI14_18165	COG1522	sequence-specific DNA binding
CAI14_18170	COG3186	Phenylalanine-4-hydroxylase
CAI14_18185	COG2755	lipolytic protein G-D-S-L family
CAI14_18195	COG1028	Short-chain dehydrogenase reductase Sdr
CAI14_18200	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CAI14_18215	COG1609	Transcriptional regulator
CAI14_18220	COG3507	Belongs to the glycosyl hydrolase 43 family
CAI14_18235	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CAI14_18245	COG0657	acetylesterase activity
CAI14_18245	COG2755	lipolytic protein G-D-S-L family
CAI14_18265	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CAI14_18270	COG0366	Alpha amylase catalytic
CAI14_18275	COG0366	Alpha amylase catalytic
CAI14_18360	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CAI14_18395	COG2937	Belongs to the GPAT DAPAT family
CAI14_18430	COG0284	orotidine-5'-phosphate decarboxylase activity
CAI14_18435	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
CAI14_18445	COG3132	Protein of unknown function, DUF480
CAI14_18460	COG0210	DNA helicase
CAI14_18480	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CAI14_18510	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CAI14_18515	COG0739	heme binding
CAI14_18520	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CAI14_18530	COG2211	Major facilitator Superfamily
CAI14_18535	COG0708	Exodeoxyribonuclease III
CAI14_18540	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CAI14_18550	COG1192	Involved in chromosome partitioning
CAI14_18555	COG1475	DNA binding
CAI14_18575	COG0463	Glycosyl transferase, family 2
CAI14_18595	COG0756	dUTP diphosphatase activity
CAI14_18600	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CAI14_18605	COG2003	Belongs to the UPF0758 family
CAI14_18610	COG0018	arginyl-trna synthetase
CAI14_18625	COG4221	oxidoreductase activity
CAI14_18630	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CAI14_18630	COG2755	lipolytic protein G-D-S-L family
CAI14_18640	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CAI14_18645	COG1166	arginine decarboxylase activity
CAI14_18650	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CAI14_18695	COG2960	long-chain fatty acid transporting porin activity
CAI14_18700	COG0606	chelatase, subunit chli
CAI14_18715	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CAI14_18750	COG1690	Belongs to the RtcB family
CAI14_18785	COG1090	epimerase
CAI14_18790	COG0745	RESPONSE REGULATOR receiver
CAI14_18795	COG0642	Histidine kinase
CAI14_18825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CAI14_18850	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CAI14_18855	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CAI14_18870	COG0753	catalase activity
CAI14_18895	COG2197	response regulator
CAI14_18900	COG4585	Histidine kinase
CAI14_18905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CAI14_18910	COG1136	(ABC) transporter
CAI14_18940	COG0697	spore germination
CAI14_18960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CAI14_18965	COG0180	Tryptophanyl-tRNA synthetase
CAI14_18970	COG3237	CsbD-like
CAI14_19015	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CAI14_19065	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CAI14_19070	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CAI14_19070	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CAI14_19100	COG2205	protein histidine kinase activity
CAI14_19105	COG0745	RESPONSE REGULATOR receiver
CAI14_19115	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CAI14_19145	COG1199	ATP-dependent helicase activity
CAI14_19160	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CAI14_19225	COG0625	glutathione transferase activity
CAI14_19265	COG4555	ABC transporter
CAI14_19275	COG1476	TRANSCRIPTIONal
CAI14_19320	COG0633	Ferredoxin
CAI14_19320	COG0543	2 iron, 2 sulfur cluster binding
CAI14_19325	COG1131	(ABC) transporter
CAI14_19330	COG0842	Transport permease protein
CAI14_19340	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CAI14_19375	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CAI14_19385	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CAI14_19400	COG0045	succinate-CoA ligase (ADP-forming) activity
CAI14_19400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CAI14_19400	COG1042	CoA-binding domain protein
CAI14_19425	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CAI14_19430	COG3387	PFAM Glycoside hydrolase 15-related
CAI14_19445	COG3100	YcgL domain-containing protein
CAI14_19450	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CAI14_19470	COG1028	Short-chain dehydrogenase reductase Sdr
CAI14_19510	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CAI14_19525	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CAI14_19555	COG1506	peptidase
CAI14_19555	COG4946	Tricorn protease homolog
CAI14_19555	COG0823	Involved in the tonB-independent uptake of proteins
CAI14_19575	COG0408	coproporphyrinogen oxidase activity
CAI14_19620	COG0631	protein serine/threonine phosphatase activity
CAI14_19655	COG3501	Rhs element vgr protein
CAI14_19815	COG0210	DNA helicase
CAI14_19830	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CAI14_19835	COG0583	DNA-binding transcription factor activity
CAI14_19840	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CAI14_19855	COG2159	amidohydrolase
CAI14_19885	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CAI14_19905	COG0357	Ribosomal RNA small subunit methyltransferase G
CAI14_19910	COG3540	Alkaline phosphatase
CAI14_19920	COG2091	lysine biosynthetic process via aminoadipic acid
CAI14_19935	COG0708	Exodeoxyribonuclease III
CAI14_19940	COG1846	Transcriptional regulator
CAI14_19940	COG1940	carbohydrate kinase activity
CAI14_19950	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CAI14_19960	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CAI14_19965	COG3162	membrane
CAI14_19975	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CAI14_20015	COG3507	Belongs to the glycosyl hydrolase 43 family
CAI14_20035	COG1028	Short-chain dehydrogenase reductase Sdr
CAI14_20040	COG0179	Fumarylacetoacetate (FAA) hydrolase
CAI14_20050	COG4948	Mandelate Racemase Muconate Lactonizing
CAI14_20055	COG3254	rhamnose metabolic process
CAI14_20060	COG0738	Major facilitator superfamily
CAI14_20065	COG1414	Transcriptional regulator
CAI14_20075	COG1971	Probably functions as a manganese efflux pump
CAI14_20080	COG2205	protein histidine kinase activity
CAI14_20095	COG3459	Glycosyltransferase 36 associated
CAI14_20100	COG2211	Major facilitator Superfamily
CAI14_20105	COG3265	gluconokinase activity
CAI14_20115	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CAI14_20135	COG2911	Protein conserved in bacteria
CAI14_20140	COG0729	surface antigen
CAI14_20190	COG0752	glycyl-tRNA synthetase alpha subunit
CAI14_20210	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CAI14_20210	COG0519	Catalyzes the synthesis of GMP from XMP
CAI14_20220	COG0805	protein transport
CAI14_20225	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CAI14_20230	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CAI14_20240	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CAI14_20265	COG2974	May be involved in recombination
CAI14_20270	COG0037	tRNA processing
CAI14_20280	COG2115	Belongs to the xylose isomerase family
CAI14_20300	COG4948	Mandelate Racemase Muconate Lactonizing
CAI14_20310	COG1472	Belongs to the glycosyl hydrolase 3 family
CAI14_20315	COG0246	Mannitol dehydrogenase
CAI14_20360	COG3002	Belongs to the UPF0753 family
CAI14_20415	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CAI14_20465	COG3318	Belongs to the UPF0149 family
CAI14_20465	COG3012	SEC-C Motif Domain Protein
CAI14_20485	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CAI14_20505	COG0662	Cupin 2, conserved barrel domain protein
CAI14_20525	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CAI14_20555	COG0714	Associated with various cellular activities
CAI14_20595	COG0477	Major facilitator Superfamily
CAI14_20605	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CAI14_20650	COG3237	CsbD-like
CAI14_20675	COG2249	NAD(P)H dehydrogenase (quinone) activity
CAI14_20690	COG1028	Short-chain dehydrogenase reductase Sdr
CAI14_20695	COG0300	oxidoreductase activity
CAI14_20715	COG1272	protein, Hemolysin III
CAI14_20720	COG1111	helicase
CAI14_20720	COG1205	dead DEAH box helicase
CAI14_20820	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CAI14_20850	COG1132	(ABC) transporter
CAI14_20900	COG0297	glycogen (starch) synthase activity
CAI14_20900	COG0438	transferase activity, transferring glycosyl groups
CAI14_20930	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CAI14_20980	COG0070	glutamate synthase
CAI14_20980	COG0069	glutamate synthase activity
CAI14_20980	COG0067	glutamate synthase
CAI14_20985	COG0493	'glutamate synthase
CAI14_20990	COG1064	alcohol dehydrogenase
CAI14_21000	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CAI14_21010	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CAI14_21020	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CAI14_21030	COG2234	aminopeptidase activity
CAI14_21040	COG4942	peptidase
CAI14_21045	COG0793	Belongs to the peptidase S41A family
CAI14_21100	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CAI14_21110	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CAI14_21140	COG0501	Belongs to the peptidase M48B family
CAI14_21150	COG0187	DNA topoisomerase II activity
CAI14_21155	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CAI14_21165	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CAI14_21175	COG0594	ribonuclease P activity
CAI14_21180	COG0706	membrane insertase activity
CAI14_21185	COG0726	polysaccharide deacetylase
CAI14_21190	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CAI14_21205	COG0584	glycerophosphoryl diester phosphodiesterase
CAI14_21220	COG0861	Integral membrane protein TerC family
CAI14_21230	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CAI14_21275	COG0531	amino acid
CAI14_21285	COG0625	glutathione transferase activity
CAI14_21300	COG0583	DNA-binding transcription factor activity
CAI14_21305	COG0604	alcohol dehydrogenase
CAI14_21310	COG1322	Protein conserved in bacteria
CAI14_21320	COG0386	Belongs to the glutathione peroxidase family
CAI14_21330	COG2853	Lipoprotein
CAI14_21345	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CAI14_21350	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CAI14_21355	COG1127	ABC transporter
CAI14_21370	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CAI14_21375	COG1074	ATP-dependent DNA helicase activity
CAI14_21395	COG3039	Transposase
CAI14_21470	COG0564	pseudouridine synthase activity
CAI14_21510	COG1309	transcriptional regulator
CAI14_21520	COG1028	Short-chain dehydrogenase reductase Sdr
CAI14_21540	COG1487	ribonuclease activity
CAI14_21545	COG4691	Plasmid stability protein
CAI14_21565	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CAI14_21575	COG0477	Major facilitator Superfamily
CAI14_21580	COG1289	transmembrane transporter activity
CAI14_21590	COG1566	PFAM secretion protein HlyD family protein
CAI14_21605	COG0302	gtp cyclohydrolase
CAI14_21625	COG0730	response to heat
CAI14_21630	COG3012	SEC-C Motif Domain Protein
CAI14_21640	COG0676	glucose-6-phosphate 1-epimerase activity
CAI14_21665	COG3135	benzoate transporter
CAI14_21705	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CAI14_21720	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
CAI14_21750	COG0109	protoheme IX farnesyltransferase activity
CAI14_21765	COG0358	DNA primase activity
CAI14_21770	COG1295	ribonuclease BN
CAI14_21780	COG1610	YqeY-like protein
CAI14_21790	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CAI14_21795	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CAI14_21805	COG2133	pyrroloquinoline quinone binding
CAI14_21810	COG4682	membrane
CAI14_21825	COG0531	amino acid
CAI14_21835	COG4948	Mandelate Racemase Muconate Lactonizing
CAI14_21845	COG3023	N-Acetylmuramoyl-L-alanine amidase
CAI14_21850	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CAI14_21900	COG5383	Protein conserved in bacteria
CAI14_21910	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CAI14_21915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CAI14_21920	COG1473	amidohydrolase
CAI14_21925	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CAI14_21925	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CAI14_21930	COG1652	LysM domain
CAI14_21940	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CAI14_21945	COG1518	maintenance of DNA repeat elements
CAI14_21990	COG0583	DNA-binding transcription factor activity
CAI14_21995	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
CAI14_22000	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CAI14_22005	COG3118	belongs to the thioredoxin family
CAI14_22010	COG0513	Belongs to the DEAD box helicase family
CAI14_22015	COG2884	Cell division ATP-binding protein ftsE
CAI14_22020	COG2177	Part of the ABC transporter FtsEX involved in
CAI14_22025	COG3437	response regulator, receiver
CAI14_22030	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CAI14_22035	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CAI14_22045	COG1252	NADH dehydrogenase
CAI14_22060	COG0625	glutathione transferase activity
CAI14_22065	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CAI14_22085	COG0534	Mate efflux family protein
CAI14_22090	COG0616	signal peptide processing
CAI14_22100	COG1028	Short-chain dehydrogenase reductase Sdr
CAI14_22115	COG0009	L-threonylcarbamoyladenylate synthase
CAI14_22120	COG1754	DNA topoisomerase type I activity
CAI14_22120	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CAI14_22140	COG0758	DNA mediated transformation
CAI14_22145	COG1652	LysM domain
CAI14_22150	COG0242	peptide deformylase activity
CAI14_22155	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CAI14_22160	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CAI14_22160	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CAI14_22215	COG1560	Kdo2-lipid A biosynthetic process
CAI14_22220	COG1490	D-aminoacyl-tRNA deacylase activity
CAI14_22225	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CAI14_22300	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CAI14_22305	COG0583	DNA-binding transcription factor activity
CAI14_22320	COG0840	transmembrane signaling receptor activity
CAI14_22335	COG0251	oxidation-reduction process
CAI14_22410	COG1063	alcohol dehydrogenase
CAI14_22435	COG1132	(ABC) transporter
CAI14_22465	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CAI14_22470	COG1028	Short-chain dehydrogenase reductase Sdr
CAI14_22490	COG1294	oxidase, subunit
CAI14_22495	COG1271	oxidase subunit
CAI14_22545	COG3546	catalase activity
CAI14_22550	COG3685	Protein conserved in bacteria
CAI14_22575	COG2972	Histidine kinase
CAI14_22590	COG0531	amino acid
CAI14_22610	COG3590	peptidase
CAI14_22625	COG0667	Aldo Keto reductase
CAI14_22645	COG3384	dioxygenase
CAI14_22655	COG1573	uracil-dna glycosylase
CAI14_22660	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CAI14_22670	COG0025	NhaP-type Na H and K H
CAI14_22675	COG1131	(ABC) transporter
CAI14_22680	COG0842	Transport permease protein
CAI14_22740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CAI14_22745	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CAI14_22765	COG2205	protein histidine kinase activity
CAI14_22765	COG2202	Pas domain
CAI14_22785	COG2813	Specifically methylates the guanine in position
CAI14_22790	COG1187	pseudouridine synthase activity
CAI14_22795	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CAI14_22820	COG5002	protein histidine kinase activity
CAI14_22820	COG2198	Histidine kinase
CAI14_22820	COG0784	Response regulator, receiver
CAI14_22830	COG1666	GTP binding
CAI14_22835	COG0697	spore germination
CAI14_22845	COG2011	ABC-type metal ion transport system permease component
CAI14_22890	COG0508	dehydrogenase complex catalyzes the overall conversion of
CAI14_22900	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CAI14_22920	COG0356	it plays a direct role in the translocation of protons across the membrane
CAI14_22930	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CAI14_22980	COG1192	Involved in chromosome partitioning
CAI14_23080	COG3704	protein secretion by the type IV secretion system
CAI14_23090	COG3504	Conjugal transfer protein
CAI14_23095	COG2948	multi-organism process
CAI14_23310	COG4691	Plasmid stability protein
CAI14_23315	COG1487	ribonuclease activity
CAI14_23375	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CAI14_23390	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CAI14_23505	COG1192	Involved in chromosome partitioning
CAI14_23650	COG3012	SEC-C Motif Domain Protein
CAI14_23650	COG3318	Belongs to the UPF0149 family