locus-tag	class	description
CAI18_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
CAI18_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
CAI18_00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
CAI18_00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CAI18_00030	ENOG4108K0D	peptidase, M48
CAI18_00060	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
CAI18_00070	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
CAI18_00105	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
CAI18_00125	ENOG4105CN1	protease
CAI18_00130	ENOG41063SB	peptidase
CAI18_00140	ENOG4107VAM	peptidase, m28
CAI18_00180	ENOG4105DQ4	alcohol dehydrogenase
CAI18_00185	ENOG4105BZ8	glutamate synthase
CAI18_00190	ENOG4105CBC	glutamate synthase
CAI18_00220	ENOG4105EXG	Transcriptional regulator
CAI18_00240	ENOG4105D3Q	Sugar transferase
CAI18_00245	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
CAI18_00270	ENOG4107RA4	Glycosyl transferase (Group 1
CAI18_00305	ENOG4105CMR	udp-glucose 4-epimerase
CAI18_00320	ENOG4105BZ1	(ABC) transporter
CAI18_00350	ENOG4107W2Z	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) (By similarity)
CAI18_00450	ENOG4108I5C	dEAD DEAH box helicase
CAI18_00455	ENOG4108UT2	hemolysin iii
CAI18_00475	ENOG4107FW0	short-chain dehydrogenase reductase
CAI18_00480	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
CAI18_00495	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
CAI18_00520	ENOG41067RQ	csbd family
CAI18_00540	ENOG4105D4Y	metalloprotease
CAI18_00565	ENOG4105K63	Thioredoxin
CAI18_00575	ENOG4105CSH	Transporter
CAI18_00615	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
CAI18_00645	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CAI18_00650	ENOG4105CGF	Aromatic amino acid aminotransferase
CAI18_00665	ENOG41082W1	Cupin 2, conserved barrel domain protein
CAI18_00685	ENOG4108C33	Resolvase
CAI18_00705	ENOG4106RHG	Yeca family
CAI18_00755	ENOG4108C33	Resolvase
CAI18_00810	ENOG4105EVH	UPF0753 protein
CAI18_00855	ENOG4105DEI	Mannitol dehydrogenase
CAI18_00870	ENOG4105CXK	mandelate racemase muconate lactonizing
CAI18_00885	ENOG4105ETE	Transcriptional regulator (LacI family
CAI18_00890	ENOG4105C93	Xylose Isomerase
CAI18_00900	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
CAI18_00905	ENOG4105DH7	May be involved in recombination (By similarity)
CAI18_00930	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
CAI18_00945	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
CAI18_00950	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
CAI18_00960	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
CAI18_00980	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
CAI18_01030	ENOG4105CFU	surface antigen
CAI18_01035	ENOG4105MA0	exported protein
CAI18_01065	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
CAI18_01070	ENOG4105CT4	transporter
CAI18_01075	ENOG4105E2V	Glycosyltransferase 36
CAI18_01090	ENOG4105BZU	Histidine kinase
CAI18_01095	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
CAI18_01105	ENOG4108K2P	TRANSCRIPTIONal
CAI18_01110	ENOG4105EDR	glucose galactose transporter
CAI18_01115	ENOG4105QJH	Domain of unknown function (DUF718)
CAI18_01120	ENOG4105DIA	mandelate racemase muconate lactonizing
CAI18_01130	ENOG4105ERH	Fumarylacetoacetate hydrolase
CAI18_01135	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
CAI18_01155	ENOG4105DSG	hydrolase family 43
CAI18_01195	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
CAI18_01205	ENOG41062QD	Membrane
CAI18_01210	ENOG4107QN1	sodium solute
CAI18_01220	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
CAI18_01230	ENOG4105E2R	ROK family
CAI18_01235	ENOG4105CGK	Exodeoxyribonuclease III
CAI18_01260	ENOG4105DGI	Alkaline phosphatase
CAI18_01265	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
CAI18_01285	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
CAI18_01315	ENOG4105KHM	amidohydrolase 2
CAI18_01330	ENOG4105JSC	dimethylmenaquinone methyltransferase
CAI18_01335	ENOG4108KB2	LysR family Transcriptional regulator
CAI18_01340	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
CAI18_01355	ENOG4105C4R	Atp-dependent dna helicase
CAI18_01400	ENOG4108WC9	type VI secretion system effector, hcp1 family
CAI18_01470	ENOG4105D6F	Phosphatase
CAI18_01515	ENOG4105CS6	Rhs element vgr protein
CAI18_01550	ENOG4108ZF3	Phosphatase
CAI18_01555	ENOG4107TPY	serine threonine protein kinase
CAI18_01585	ENOG4105C2M	dna polymerase I
CAI18_01595	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
CAI18_01615	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
CAI18_01645	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
CAI18_01655	ENOG4105E9Q	Acyl-transferase
CAI18_01660	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
CAI18_01710	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
CAI18_01720	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
CAI18_01740	ENOG4105BZP	glycoside hydrolase 15-related
CAI18_01745	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
CAI18_01765	ENOG4105CJW	magnesium transporter
CAI18_01770	ENOG4105CD5	CoA-binding domain protein
CAI18_01785	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CAI18_01795	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CAI18_01830	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
CAI18_01840	ENOG4105E3A	(ABC) transporter
CAI18_01845	ENOG4105DA5	(ABC) transporter
CAI18_01850	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
CAI18_01855	ENOG4105ECQ	AraC Family Transcriptional Regulator
CAI18_01865	ENOG4105E0K	tonB-dependent siderophore receptor
CAI18_01875	ENOG4105PGM	cation diffusion facilitator family transporter
CAI18_01895	ENOG4105VZ8	Transcriptional regulator
CAI18_01905	ENOG4108IUW	ABC transporter
CAI18_01945	ENOG4105CYM	Glutathione S-transferase
CAI18_01975	ENOG4105D52	delta-aminolevulinic acid dehydratase
CAI18_02000	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
CAI18_02010	ENOG4105E2X	shikimate dehydrogenase
CAI18_02025	ENOG4105DVT	helicase
CAI18_02035	ENOG4105CH6	catalase
CAI18_02055	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
CAI18_02065	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
CAI18_02070	ENOG4105EB3	Histidine kinase
CAI18_02100	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
CAI18_02200	ENOG4105VDW	Csbd family
CAI18_02205	ENOG4105C31	Tryptophanyl-tRNA synthetase
CAI18_02210	ENOG4108NNI	Beta-lactamase domain-containing protein
CAI18_02230	ENOG4105FDR	Membrane
CAI18_02260	ENOG4105C19	ABC transporter
CAI18_02265	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
CAI18_02270	ENOG4108ZGX	Histidine kinase
CAI18_02275	ENOG4108S01	response regulator
CAI18_02300	ENOG4107VGR	Catalase
CAI18_02315	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
CAI18_02320	ENOG4107URF	beta-phospho-glucomutase
CAI18_02325	ENOG4105DSF	transport protein
CAI18_02345	ENOG4105C0H	protease
CAI18_02375	ENOG4105DHQ	Histidine kinase
CAI18_02380	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
CAI18_02385	ENOG4105ECP	epimerase
CAI18_02420	ENOG4105E0Y	RtcB Protein
CAI18_02440	ENOG4105EJ2	Transcriptional regulator
CAI18_02455	ENOG41066DG	(EAL) domain protein
CAI18_02470	ENOG4105C0P	Mg chelatase subunit ChlI
CAI18_02475	ENOG4105W0Z	cytoplasmic protein
CAI18_02480	ENOG4108YZA	Nitrogen regulatory protein pii
CAI18_02520	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
CAI18_02525	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
CAI18_02530	ENOG4105CEY	Amp-dependent synthetase and ligase
CAI18_02540	ENOG4105EXC	Acyl-transferase
CAI18_02545	ENOG4105EMU	Dehydrogenase
CAI18_02560	ENOG4105C75	arginyL-tRNA synthetase
CAI18_02565	ENOG4105W5Q	DNA repair protein (RadC
CAI18_02570	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
CAI18_02575	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
CAI18_02580	ENOG4107QKV	phosphomannomutase
CAI18_02595	ENOG4105CKK	Glycosyl transferase, family 2
CAI18_02615	ENOG4105FA0	parb-like partition protein
CAI18_02620	ENOG4107QJE	Chromosome Partitioning Protein
CAI18_02630	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
CAI18_02635	ENOG4105CGK	Exodeoxyribonuclease III
CAI18_02640	ENOG4105EYM	Major Facilitator superfamily
CAI18_02650	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
CAI18_02655	ENOG4105DR5	peptidase
CAI18_02660	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
CAI18_02690	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
CAI18_02710	ENOG4105C4R	Atp-dependent dna helicase
CAI18_02715	ENOG4105KNA	-acetyltransferase
CAI18_02725	ENOG4108YXG	UPF0502 protein
CAI18_02735	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
CAI18_02740	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
CAI18_02745	ENOG4105QV4	Tryptophan halogenase
CAI18_02760	ENOG4105ETE	Transcriptional regulator (LacI family
CAI18_02775	ENOG4105E55	glycerol-3-phosphate acyltransferase
CAI18_02810	ENOG4105RKW	reductase (By
CAI18_02895	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
CAI18_02900	ENOG4105CG3	alpha amylase, catalytic region
CAI18_02905	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
CAI18_02920	ENOG4105EBR	Carboxylesterase
CAI18_02935	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
CAI18_02945	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CAI18_02950	ENOG4105DSG	hydrolase family 43
CAI18_02955	ENOG4105ETE	Transcriptional regulator (LacI family
CAI18_02965	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
CAI18_02970	ENOG4105CHR	reductase
CAI18_02980	ENOG4107TDE	lipolytic protein G-D-S-L family
CAI18_02995	ENOG4105MIR	Phenylalanine 4-monooxygenase
CAI18_03000	ENOG4108YXU	transcriptional regulator AsnC family
CAI18_03005	ENOG4105CNM	Receptor
CAI18_03010	ENOG4105D78	K07001 NTE family protein
CAI18_03020	ENOG4105DKW	ABC transporter
CAI18_03035	ENOG4108IJ8	ABC transporter
CAI18_03040	ENOG4105E90	ABC transporter
CAI18_03105	ENOG4105D1F	ATP-binding protein
CAI18_03110	ENOG4105M4E	phosphohistidine phosphatase, SixA
CAI18_03120	ENOG4107RZC	phospholipase d
CAI18_03125	ENOG4105KA0	thioesterase Superfamily protein
CAI18_03165	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
CAI18_03175	ENOG4105C5F	glutamine synthetase
CAI18_03185	ENOG4105BZU	Histidine kinase
CAI18_03190	ENOG4105CUX	Signal transduction histidine kinase
CAI18_03195	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CAI18_03200	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
CAI18_03205	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
CAI18_03220	ENOG4105CHU	acetyl-coa acetyltransferase
CAI18_03255	ENOG4107YZP	Rhodanese domain protein
CAI18_03260	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
CAI18_03265	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
CAI18_03320	ENOG4105D00	flagellar biosynthetic protein flhB
CAI18_03325	ENOG4105D7B	Flagellar biosynthesis protein flha
CAI18_03330	ENOG4108JQA	flagellar
CAI18_03335	ENOG4105CGA	flagellar basal-body rod protein FlgG
CAI18_03345	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
CAI18_03350	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
CAI18_03365	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
CAI18_03370	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
CAI18_03410	ENOG410822I	Flagellar hook capping protein
CAI18_03415	ENOG4105BZE	flagellar hook protein, FlgE
CAI18_03425	ENOG4105DD5	Flagellar motor switch protein
CAI18_03435	ENOG4105CN7	Flagellar biosynthetic protein FliP
CAI18_03440	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CAI18_03445	ENOG4105C7K	acetolactate synthase
CAI18_03450	ENOG4108TQ9	Histidine kinase
CAI18_03455	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CAI18_03475	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
CAI18_03490	ENOG4105E2T	synthase III
CAI18_03495	ENOG4107R3N	Filamentation induced by cAMP protein fic
CAI18_03500	ENOG4108J2P	Alpha beta hydrolase fold
CAI18_03505	ENOG4105PI0	Ferredoxin
CAI18_03510	ENOG410680H	amp-dependent synthetase and ligase
CAI18_03515	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
CAI18_03540	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
CAI18_03550	ENOG4105DR9	pseudouridine synthase
CAI18_03560	ENOG4108YZN	class I peptide chain release factor
CAI18_03570	ENOG4105D44	asparaginase
CAI18_03575	ENOG4105DGW	oligopeptidase A
CAI18_03610	ENOG4107R11	Transcriptional regulator
CAI18_03615	ENOG4107QP3	malate synthase g
CAI18_03625	ENOG4105BZU	Histidine kinase
CAI18_03665	ENOG4107QX3	carboxylase
CAI18_03670	ENOG4105C1G	acyl-Coa dehydrogenase
CAI18_03675	ENOG4108RZE	Tetr family transcriptional regulator
CAI18_03730	ENOG4105CKI	cobalamin synthesis protein
CAI18_03750	ENOG4105D6Z	AFG1 family ATPase
CAI18_03755	ENOG4105K56	Transcriptional regulator
CAI18_03760	ENOG4108ZHJ	Organic hydroperoxide resistance protein
CAI18_03790	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
CAI18_03805	ENOG4108R99	pseudouridine synthase
CAI18_03820	ENOG4105CQ7	ATP-dependent helicase
CAI18_03825	ENOG4108W15	Protein of unknown function (DUF1456)
CAI18_03830	ENOG4105VT2	5-hydroxyisourate hydrolase
CAI18_03835	ENOG4105E1J	oxidoreductase
CAI18_03855	ENOG4105C5R	Aminotransferase
CAI18_03865	ENOG4105EQ2	LysR family Transcriptional regulator
CAI18_03870	ENOG4107RTG	Major Facilitator superfamily
CAI18_03880	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
CAI18_03890	ENOG4105DU0	nucleoside hydrolase
CAI18_03900	ENOG4105C7N	Xanthine uracil vitamin C permease
CAI18_03920	ENOG4105ETT	transcriptional Regulator, LysR family
CAI18_03925	ENOG4105F8V	Hydrolase, tatD family
CAI18_03945	ENOG4106NZI	LysR family Transcriptional regulator
CAI18_03950	ENOG4105D94	Major Facilitator Superfamily
CAI18_03965	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
CAI18_03970	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
CAI18_03990	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
CAI18_03995	ENOG4105EB3	Histidine kinase
CAI18_04000	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
CAI18_04005	ENOG4105BZS	acriflavin resistance protein
CAI18_04010	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
CAI18_04025	ENOG4105WPN	DNA integration recombination invertion protein
CAI18_04030	ENOG4105DZ2	Transcriptional regulator
CAI18_04035	ENOG4108UZX	fmn reductase
CAI18_04050	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
CAI18_04065	ENOG4105ECR	NmrA family
CAI18_04115	ENOG4105C01	Dihydroxy-acid dehydratase
CAI18_04130	ENOG4108Z0R	Transferase
CAI18_04140	ENOG4105D2S	major facilitator superfamily
CAI18_04145	ENOG4105CPI	Metal Dependent Phosphohydrolase
CAI18_04180	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
CAI18_04190	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
CAI18_04195	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
CAI18_04200	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
CAI18_04205	ENOG4105E98	transcriptional regulator DeoR family
CAI18_04235	ENOG4105CHU	acetyl-coa acetyltransferase
CAI18_04250	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
CAI18_04255	ENOG4105F2Z	3-oxoadipate enol-lactonase
CAI18_04260	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
CAI18_04270	ENOG4107HP6	Transcriptional regulator
CAI18_04285	ENOG4105MH3	Protein of unknown function (DUF2490)
CAI18_04290	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
CAI18_04325	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
CAI18_04330	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
CAI18_04340	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
CAI18_04345	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
CAI18_04350	ENOG41081UC	Inherit from COG: Competence protein
CAI18_04355	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
CAI18_04425	ENOG4105VS8	Flagellar biosynthetic protein fliq
CAI18_04445	ENOG4108HR8	type iii secretion
CAI18_04465	ENOG4107Y59	type iii secretion
CAI18_04480	ENOG4108JIR	Flagellum-specific ATP synthase
CAI18_04490	ENOG4108TN6	type iii secretion
CAI18_04505	ENOG4105FTC	Lytic transglycosylase catalytic
CAI18_04520	ENOG4105EGS	Mechanosensitive ion channel
CAI18_04525	ENOG4107RES	phosphoglycerol transferase I
CAI18_04540	ENOG4105CKW	Inner membrane protein yedI
CAI18_04550	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
CAI18_04555	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
CAI18_04560	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
CAI18_04585	ENOG4105K4T	epimerase
CAI18_04590	ENOG4107ZQV	short-chain dehydrogenase reductase
CAI18_04625	ENOG4105BZS	acriflavin resistance protein
CAI18_04630	ENOG4105CHR	reductase
CAI18_04645	ENOG4105C1J	atp-dependent rna helicase
CAI18_04660	ENOG4105CPP	Dehydrogenase, E1 component
CAI18_04665	ENOG4107RUY	(E1 component), alpha subunit
CAI18_04680	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
CAI18_04685	ENOG4105DUX	Transporter
CAI18_04700	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
CAI18_04710	ENOG4105F1J	Homogentisate 1,2-dioxygenase
CAI18_04730	ENOG4105KJM	monovalent cation h antiporter subunit g
CAI18_04735	ENOG4105W4C	monovalent cation H antiporter subunit F
CAI18_04745	ENOG4107R4Z	monovalent cation h antiporter subunit d
CAI18_04750	ENOG4108ZE9	Monovalent cation H antiporter subunit C
CAI18_04755	ENOG4105D65	subunit l
CAI18_04780	ENOG4105NVB	glycoside hydrolase, family 19
CAI18_04800	ENOG4105C8V	SAICAR synthetase
CAI18_04805	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
CAI18_04820	ENOG4105KD7	acetyltransferase
CAI18_04825	ENOG4107TE5	Lipid kinase
CAI18_04830	ENOG4105CRQ	synthase (Component I)
CAI18_04840	ENOG4105DDQ	anthranilate synthase
CAI18_04850	ENOG4108I0Q	anthranilate phosphoribosyltransferase
CAI18_04855	ENOG4105DK0	Indole-3-glycerol phosphate synthase
CAI18_04865	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
CAI18_04870	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
CAI18_04880	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
CAI18_04890	ENOG4108UJD	30S ribosomal protein S9
CAI18_04905	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
CAI18_04915	ENOG4108UQY	Iron-storage protein
CAI18_04920	ENOG4105BZU	Histidine kinase
CAI18_04945	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
CAI18_04965	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
CAI18_04985	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
CAI18_05000	ENOG4105EM2	membrane
CAI18_05010	ENOG4105C12	Phosphoribosylglycinamide synthetase
CAI18_05020	ENOG4105DC1	bifunctional purine biosynthesis protein purh
CAI18_05025	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
CAI18_05030	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
CAI18_05035	ENOG41077RS	Phosphatase
CAI18_05060	ENOG4108HPI	phosphatidate Cytidylyltransferase
CAI18_05065	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
CAI18_05090	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
CAI18_05110	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
CAI18_05120	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
CAI18_05125	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
CAI18_05130	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
CAI18_05135	ENOG4105VF7	tolerance protein
CAI18_05150	ENOG4105VV6	START domain-containing protein
CAI18_05165	ENOG4105E1F	short-chain dehydrogenase reductase
CAI18_05175	ENOG4108K8S	endonuclease I
CAI18_05185	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
CAI18_05200	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
CAI18_05225	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
CAI18_05230	ENOG4105EX9	Membrane
CAI18_05250	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
CAI18_05255	ENOG4108YYC	ycei family
CAI18_05285	ENOG4105WSE	Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity)
CAI18_05300	ENOG41065ZS	Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme- A to the apo- acyl-carrier-protein of the malonate decarboxylase to yield holo- acyl-carrier-protein (By similarity)
CAI18_05320	ENOG4105DRR	Transcriptional regulator, GntR family
CAI18_05360	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
CAI18_05395	ENOG4107GJV	short-chain dehydrogenase reductase
CAI18_05410	ENOG4105PDP	Short chain dehydrogenase
CAI18_05425	ENOG4105CHF	Glutathione S-transferase
CAI18_05450	ENOG4105EYF	MMPL domain protein
CAI18_05460	ENOG4105C5Z	peptidase
CAI18_05470	ENOG4107QS8	(LipO)protein
CAI18_05480	ENOG4105BZU	Histidine kinase
CAI18_05505	ENOG4105DFI	Membrane
CAI18_05510	ENOG4105F87	Dehydratase
CAI18_05540	ENOG4105E53	ec 3.2.1.28
CAI18_05600	ENOG4105C8Q	Methyl-accepting chemotaxis
CAI18_05605	ENOG4106R7G	Glycoside hydrolase family 5
CAI18_05610	ENOG4105CHH	sulfate transporter
CAI18_05620	ENOG4105BZU	Histidine kinase
CAI18_05640	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
CAI18_05650	ENOG4108HRK	Histidine kinase
CAI18_05655	ENOG4108NEV	two component transcriptional regulator, LytTR family
CAI18_05660	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
CAI18_05720	ENOG4105WD1	Membrane
CAI18_05730	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
CAI18_05740	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CAI18_05745	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
CAI18_05750	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
CAI18_05775	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CAI18_05780	ENOG41064RH	membrane protein YliF
CAI18_05785	ENOG4105CD8	aminopeptidase N
CAI18_05820	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
CAI18_05835	ENOG4107QW3	Sucrose phosphorylase
CAI18_05850	ENOG4105ETE	Transcriptional regulator (LacI family
CAI18_05855	ENOG4105CHR	reductase
CAI18_05860	ENOG4105D4T	Citrate transporter
CAI18_05880	ENOG4105DHQ	Histidine kinase
CAI18_05885	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
CAI18_05895	ENOG4105WH1	Two component transcriptional regulator luxr family
CAI18_05915	ENOG4105CPC	Aldo Keto reductase
CAI18_05925	ENOG4105F04	LysR family Transcriptional regulator
CAI18_05935	ENOG4105CSH	Transporter
CAI18_05945	ENOG4105CQZ	Histidine kinase
CAI18_05955	ENOG4105CK2	sodium dicarboxylate symporter
CAI18_05960	ENOG4105C6K	Malic enzyme
CAI18_05985	ENOG4105D1S	lipid A biosynthesis
CAI18_05990	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
CAI18_05995	ENOG4105DFG	type I secretion outer membrane protein
CAI18_06000	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
CAI18_06015	ENOG4108MP6	LysR family Transcriptional regulator
CAI18_06020	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CAI18_06025	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CAI18_06030	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
CAI18_06035	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
CAI18_06040	ENOG4105C7B	Threonine dehydratase
CAI18_06055	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
CAI18_06065	ENOG4105C8Q	Methyl-accepting chemotaxis
CAI18_06080	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
CAI18_06085	ENOG4108M3R	transcriptional activator CadC
CAI18_06090	ENOG4105ECQ	AraC Family Transcriptional Regulator
CAI18_06115	ENOG4105F0N	pyrophosphate phospho-hydrolase
CAI18_06125	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CAI18_06150	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
CAI18_06165	ENOG4105FFC	UPF0187 protein
CAI18_06170	ENOG410841Q	phosphoesterase PA-phosphatase related protein
CAI18_06190	ENOG4105EYW	Ion transport protein
CAI18_06195	ENOG4105C8Y	Acetylornithine aminotransferase
CAI18_06225	ENOG4105CIH	Imidazole acetol-phosphate transaminase
CAI18_06235	ENOG41061ZR	Transcriptional regulator
CAI18_06240	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
CAI18_06250	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
CAI18_06255	ENOG4105VCQ	rubredoxin
CAI18_06260	ENOG41063JG	Transcriptional regulator
CAI18_06270	ENOG4105E66	phosphoriboisomerase A
CAI18_06280	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
CAI18_06290	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
CAI18_06305	ENOG4107RAQ	aminopeptidase
CAI18_06315	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
CAI18_06330	ENOG4105CSA	Coproporphyrinogen iii oxidase
CAI18_06335	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
CAI18_06345	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
CAI18_06350	ENOG4105DSJ	YicC domain protein
CAI18_06355	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
CAI18_06365	ENOG4108EMV	Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity)
CAI18_06370	ENOG4105CHR	reductase
CAI18_06375	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CAI18_06390	ENOG4105TW1	Carbohydrate-selective porin OprB
CAI18_06405	ENOG4105DKT	Transcriptional regulator
CAI18_06410	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
CAI18_06415	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
CAI18_06420	ENOG4105KME	endoribonuclease L-psp
CAI18_06425	ENOG4105CB5	ATP-dependent DNA helicase recG
CAI18_06430	ENOG4105DU0	nucleoside hydrolase
CAI18_06455	ENOG4108JQC	penicillin-binding protein 1A
CAI18_06485	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
CAI18_06505	ENOG4107QVM	von Willebrand factor, type A
CAI18_06520	ENOG4105CK2	sodium dicarboxylate symporter
CAI18_06525	ENOG4105CV1	Transketolase (EC 2.2.1.1)
CAI18_06530	ENOG4107SKW	Inherit from COG: Alpha beta hydrolase
CAI18_06535	ENOG4105CNM	Receptor
CAI18_06545	ENOG4105DR5	peptidase
CAI18_06555	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
CAI18_06590	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
CAI18_06595	ENOG4105E0C	molybdate abc transporter
CAI18_06600	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
CAI18_06605	ENOG4107S76	domain protein
CAI18_06615	ENOG4105EIF	outer membrane protein W
CAI18_06620	ENOG4105EIF	outer membrane protein W
CAI18_06635	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
CAI18_06660	ENOG4105BZA	Phosphoglycerate kinase
CAI18_06670	ENOG4105CA9	Pyruvate kinase
CAI18_06675	ENOG4107R1Y	fructose-bisphosphate aldolase
CAI18_06680	ENOG4108UVJ	appr-1-p processing domain protein
CAI18_06695	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
CAI18_06700	ENOG4107R11	Transcriptional regulator
CAI18_06715	ENOG4105BZU	Histidine kinase
CAI18_06735	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
CAI18_06740	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
CAI18_06745	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
CAI18_06750	ENOG4105C11	sulfate adenylyltransferase), subunit 2
CAI18_06755	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
CAI18_06760	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
CAI18_06765	ENOG4105BZS	acriflavin resistance protein
CAI18_06835	ENOG4105EIB	trna rrna methyltransferase
CAI18_06865	ENOG4105ETE	Transcriptional regulator (LacI family
CAI18_06875	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
CAI18_06905	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
CAI18_06915	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
CAI18_06960	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
CAI18_06970	ENOG4105ETX	regulatoR
CAI18_06975	ENOG4105BZU	Histidine kinase
CAI18_07070	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
CAI18_07090	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
CAI18_07095	ENOG4107T4Z	adenosine kinase
CAI18_07105	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
CAI18_07120	ENOG4105CNI	cell division protein FtsW
CAI18_07130	ENOG4105CVE	Lytic murein transglycosylase
CAI18_07135	ENOG4105K6T	rare lipoprotein A
CAI18_07145	ENOG4105DZ1	carboxypeptidase
CAI18_07160	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
CAI18_07165	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
CAI18_07170	ENOG4105CN1	protease
CAI18_07180	ENOG4105EGI	Transcriptional regulator
CAI18_07225	ENOG4108J5G	6-phosphogluconate dehydrogenase
CAI18_07230	ENOG4105D9R	oxidoreductase
CAI18_07235	ENOG4105W4M	Transport-associated protein
CAI18_07240	ENOG4105BZU	Histidine kinase
CAI18_07250	ENOG4105BZU	Histidine kinase
CAI18_07260	ENOG4105CHR	reductase
CAI18_07305	ENOG4105GVR	general secretion pathway protein D
CAI18_07310	ENOG4107QHF	type ii secretion system protein e
CAI18_07315	ENOG4105D7Q	type ii secretion system
CAI18_07320	ENOG4108VAU	general secretion pathway protein G
CAI18_07325	ENOG4105VWV	general secretion pathway protein h
CAI18_07330	ENOG4105X5Z	General secretion pathway protein I
CAI18_07340	ENOG4108RTD	type II secretion system protein K
CAI18_07365	ENOG4105CNT	hydrolase family 2
CAI18_07390	ENOG4105ETE	Transcriptional regulator (LacI family
CAI18_07395	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
CAI18_07400	ENOG4105CE4	GlcNAc 6-P deacetylase
CAI18_07410	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CAI18_07415	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
CAI18_07420	ENOG4105C26	Dehydrogenase
CAI18_07425	ENOG4105C94	Transporter
CAI18_07450	ENOG4106RE7	Cytochrome
CAI18_07455	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
CAI18_07460	ENOG4105CY0	Metallo-Beta-Lactamase
CAI18_07480	ENOG4105JJR	Histidine kinase
CAI18_07510	ENOG4108QBQ	Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione (By similarity)
CAI18_07525	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
CAI18_07530	ENOG4105JAB	phenazine biosynthesis protein, phzf family
CAI18_07545	ENOG4105C5H	ABC transporter
CAI18_07555	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
CAI18_07560	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
CAI18_07570	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
CAI18_07585	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
CAI18_07590	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
CAI18_07595	ENOG4107YIM	Involved in the transcription termination process (By similarity)
CAI18_07600	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
CAI18_07625	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
CAI18_07630	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
CAI18_07635	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
CAI18_07640	ENOG4105C08	Histidine kinase
CAI18_07645	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
CAI18_07675	ENOG4105CQB	FAD linked oxidase domain protein
CAI18_07680	ENOG4105S2T	inner membrane protein YbcI
CAI18_07685	ENOG41082RQ	UPF0102 protein
CAI18_07725	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
CAI18_07730	ENOG4106932	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
CAI18_07735	ENOG4105CJN	penicillin-binding protein
CAI18_07740	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
CAI18_07745	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
CAI18_07750	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
CAI18_07760	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
CAI18_07765	ENOG4105DFU	Cell wall formation (By similarity)
CAI18_07770	ENOG4105CPF	Cell wall formation (By similarity)
CAI18_07775	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
CAI18_07780	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
CAI18_07785	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
CAI18_07790	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CAI18_07805	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
CAI18_07810	ENOG4105M6F	mutator MutT protein
CAI18_07820	ENOG4105SYT	Methylenetetrahydrofolate reductase
CAI18_07900	ENOG4105DXX	methyltransferase
CAI18_07905	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
CAI18_07915	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
CAI18_07960	ENOG4105D6F	Phosphatase
CAI18_07975	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
CAI18_07980	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
CAI18_07990	ENOG4108RVA	ribokinase
CAI18_07995	ENOG4105D9N	nucleoside
CAI18_08005	ENOG4105CPC	Aldo Keto reductase
CAI18_08015	ENOG4105D05	Receptor
CAI18_08035	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
CAI18_08050	ENOG4105E2B	Taurine dioxygenase
CAI18_08060	ENOG4108I0Y	(ABC) transporter
CAI18_08065	ENOG4108UJV	acyl-CoA thioesterase i
CAI18_08075	ENOG4105DHQ	Histidine kinase
CAI18_08095	ENOG41080IJ	Diacylglycerol kinase
CAI18_08110	ENOG4107RZC	phospholipase d
CAI18_08115	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
CAI18_08120	ENOG4105BZU	Histidine kinase
CAI18_08125	ENOG4105BZU	Histidine kinase
CAI18_08130	ENOG4108V3W	Chemotaxis protein, CheW
CAI18_08135	ENOG4105C8Q	Methyl-accepting chemotaxis
CAI18_08140	ENOG4105CBS	Chea signal transduction histidine kinase
CAI18_08155	ENOG4108JA2	transcriptioN-repair coupling factor
CAI18_08165	ENOG4105D6S	protein involved in catabolism of external DNA
CAI18_08175	ENOG4105EB3	Histidine kinase
CAI18_08180	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
CAI18_08190	ENOG4105CT7	inner membrane cred family protein
CAI18_08215	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
CAI18_08220	ENOG4105MYN	Zinc uptake regulation protein
CAI18_08230	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
CAI18_08235	ENOG4105BZS	acriflavin resistance protein
CAI18_08240	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
CAI18_08265	ENOG4105CC0	LysR family Transcriptional regulator
CAI18_08270	ENOG4105F27	Major Facilitator
CAI18_08315	ENOG4105UGU	tonB-dependent Receptor
CAI18_08340	ENOG4105CMQ	Chloride channel
CAI18_08355	ENOG4105D03	DNA-3-methyladenine glycosylase II
CAI18_08405	ENOG4105BZU	Histidine kinase
CAI18_08410	ENOG4105FE9	pseudouridine synthase
CAI18_08435	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
CAI18_08440	ENOG4105FQP	Beta-lactamase
CAI18_08450	ENOG4105BZU	Histidine kinase
CAI18_08455	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CAI18_08460	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
CAI18_08490	ENOG4105BZ1	(ABC) transporter
CAI18_08535	ENOG4105WG9	Conserved Protein
CAI18_08575	ENOG4107QR8	Thioredoxin
CAI18_08585	ENOG4105C8T	Leucyl-tRNA synthetase
CAI18_08600	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
CAI18_08615	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
CAI18_08635	ENOG4105MPN	Membrane
CAI18_08640	ENOG4108Z03	MAF-like protein
CAI18_08645	ENOG4105C03	ribonuclease
CAI18_08650	ENOG4105QD6	exported protein
CAI18_08660	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
CAI18_08665	ENOG4105N42	UPF0307 protein
CAI18_08670	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
CAI18_08685	ENOG4106RHG	Yeca family
CAI18_08705	ENOG4108C33	Resolvase
CAI18_08715	ENOG4105CTB	Polyprenyl synthetase
CAI18_08720	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
CAI18_08725	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
CAI18_08735	ENOG4105G6Z	alkaline phosphatase
CAI18_08745	ENOG41082K6	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
CAI18_08755	ENOG4105K4H	Nlp p60 protein
CAI18_08760	ENOG4105K4H	Nlp p60 protein
CAI18_08765	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
CAI18_08775	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
CAI18_08780	ENOG4105DC8	reductase
CAI18_08805	ENOG4105C9K	Endothelin-converting enzyme 1
CAI18_08815	ENOG4105C9K	Endothelin-converting enzyme 1
CAI18_08875	ENOG4105CNA	YD repeat protein
CAI18_08900	ENOG4105CMM	transposase
CAI18_08920	ENOG4105CNT	hydrolase family 2
CAI18_08925	ENOG4106FKC	arabinogalactan endo-1,4-beta-galactosidase
CAI18_08940	ENOG4105C26	Dehydrogenase
CAI18_08945	ENOG4105C1G	acyl-Coa dehydrogenase
CAI18_08950	ENOG4105E39	Enoyl-CoA hydratase
CAI18_08955	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
CAI18_08975	ENOG4105EMN	RNA polymerase sigma factor
CAI18_08985	ENOG4105C0H	protease
CAI18_08990	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
CAI18_08995	ENOG4105C3F	Signal peptidase i
CAI18_09005	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
CAI18_09010	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
CAI18_09025	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
CAI18_09040	ENOG4107ZXU	DSBA oxidoreductase
CAI18_09045	ENOG4108QDE	fad dependent oxidoreductase
CAI18_09050	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
CAI18_09055	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
CAI18_09060	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
CAI18_09065	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
CAI18_09075	ENOG4105VEQ	Cold shock protein
CAI18_09090	ENOG4107QRT	dEAD DEAH box helicase
CAI18_09095	ENOG4107T0X	DNA ligase
CAI18_09105	ENOG4107T0X	DNA ligase
CAI18_09135	ENOG4105CHU	acetyl-coa acetyltransferase
CAI18_09160	ENOG4108VKG	metal-dependent hydrolase
CAI18_09175	ENOG4105KSC	Transcriptional regulator, TraR DksA family
CAI18_09195	ENOG4108YZY	peptidylprolyl cis-trans isomerase
CAI18_09205	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
CAI18_09220	ENOG4105F27	Major Facilitator
CAI18_09260	ENOG4105M4H	endoribonuclease L-psp
CAI18_09265	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
CAI18_09280	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
CAI18_09305	ENOG4105K6V	RNA polymerase
CAI18_09325	ENOG4108R3D	Electron transport complex
CAI18_09335	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
CAI18_09350	ENOG4105DA5	(ABC) transporter
CAI18_09355	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
CAI18_09360	ENOG4108IQI	permease
CAI18_09365	ENOG4107QK5	Homocysteine s-methyltransferase
CAI18_09415	ENOG4108YXA	Membrane
CAI18_09430	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
CAI18_09440	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CAI18_09445	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CAI18_09450	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CAI18_09455	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
CAI18_09460	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CAI18_09475	ENOG4105DZP	Membrane-associated zinc metalloprotease
CAI18_09480	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
CAI18_09485	ENOG4105KNE	Phosphatidate cytidylyltransferase
CAI18_09490	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
CAI18_09495	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
CAI18_09500	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
CAI18_09510	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
CAI18_09515	ENOG4105CE9	30S ribosomal protein S2
CAI18_09550	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
CAI18_09565	ENOG4105KUZ	arsenate reductase
CAI18_09570	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
CAI18_09575	ENOG4105CAQ	asparagine synthetase
CAI18_09585	ENOG4108ESX	Receptor
CAI18_09595	ENOG4108UWD	Iron-storage protein
CAI18_09610	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CAI18_09630	ENOG4105CW7	secretion protein, HlyD family
CAI18_09635	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
CAI18_09660	ENOG4105DUX	Transporter
CAI18_09690	ENOG4105DGW	oligopeptidase A
CAI18_09700	ENOG4108V06	Glutathione peroxidase
CAI18_09705	ENOG4105DP0	ferredoxin-NADP reductase
CAI18_09715	ENOG4107GFK	fumarate
CAI18_09735	ENOG4105HDD	phospholipase
CAI18_09745	ENOG4105VEQ	Cold shock protein
CAI18_09760	ENOG4105CUZ	uba thif-type nad fad binding protein
CAI18_09765	ENOG4105F8V	Hydrolase, tatD family
CAI18_09780	ENOG4105C1G	acyl-Coa dehydrogenase
CAI18_09790	ENOG4108K3A	Glutathione S-transferase
CAI18_09800	ENOG4105CAQ	asparagine synthetase
CAI18_09810	ENOG4105CDU	Replicative dna helicase
CAI18_09815	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
CAI18_09825	ENOG4105CDV	Ompa motb domain protein
CAI18_09835	ENOG4105CR8	Transcriptional regulator
CAI18_09875	ENOG4105BZU	Histidine kinase
CAI18_09885	ENOG4106TD9	Diguanylate cyclase
CAI18_09915	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
CAI18_09920	ENOG4108Z1B	Cyclase dehydrase
CAI18_09930	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
CAI18_09935	ENOG41090R7	Ferric uptake
CAI18_09940	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
CAI18_09945	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
CAI18_09950	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CAI18_09955	ENOG4105CFG	Acts as a chaperone (By similarity)
CAI18_09960	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CAI18_10000	ENOG4105C5Q	Transcriptional regulator
CAI18_10005	ENOG4105BZ1	(ABC) transporter
CAI18_10015	ENOG4108URH	decarboxylase
CAI18_10025	ENOG4105C7S	Dehydrogenase
CAI18_10030	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
CAI18_10040	ENOG4105EZE	Cupin 4 family protein
CAI18_10050	ENOG4107QTF	adenylosuccinate lyase
CAI18_10060	ENOG4105C37	(CBS) domain
CAI18_10090	ENOG4105CZV	ABC transporter
CAI18_10095	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
CAI18_10110	ENOG4108V1T	peptidylprolyl cis-trans isomerase
CAI18_10115	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
CAI18_10120	ENOG41069P5	Protein slyX homolog
CAI18_10135	ENOG4105ETE	Transcriptional regulator (LacI family
CAI18_10145	ENOG4105D7K	pfkb domain protein
CAI18_10170	ENOG4105C3R	Methionine synthase
CAI18_10175	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CAI18_10180	ENOG4105C1G	acyl-Coa dehydrogenase
CAI18_10185	ENOG4105C1G	acyl-Coa dehydrogenase
CAI18_10205	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
CAI18_10215	ENOG4105C2N	RNA methyltransferase TrmH family group 3
CAI18_10220	ENOG4105BZU	Histidine kinase
CAI18_10225	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
CAI18_10235	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
CAI18_10240	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
CAI18_10245	ENOG4105E2Z	phosphate ABC transporter (Permease
CAI18_10250	ENOG4105C8U	phosphate abc transporter
CAI18_10255	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
CAI18_10280	ENOG4105CHH	sulfate transporter
CAI18_10285	ENOG4105CSM	endonuclease III
CAI18_10295	ENOG4105E39	Enoyl-CoA hydratase
CAI18_10300	ENOG4108V1T	peptidylprolyl cis-trans isomerase
CAI18_10305	ENOG4105P8F	nudix hydrolase
CAI18_10310	ENOG4105KHC	sulfurtransferase
CAI18_10350	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
CAI18_10355	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
CAI18_10380	ENOG4105CJB	Exodeoxyribonuclease I
CAI18_10390	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
CAI18_10395	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
CAI18_10405	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
CAI18_10410	ENOG41077A9	carbonic anhydrase
CAI18_10455	ENOG4105WH1	Two component transcriptional regulator luxr family
CAI18_10495	ENOG4105C5S	asparaginyl-tRNA synthetase
CAI18_10505	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
CAI18_10510	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
CAI18_10515	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
CAI18_10520	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
CAI18_10530	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
CAI18_10540	ENOG4105CIH	Imidazole acetol-phosphate transaminase
CAI18_10545	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
CAI18_10550	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
CAI18_10565	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
CAI18_10570	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CAI18_10575	ENOG4105DZG	Dehydrogenase
CAI18_10590	ENOG4105CGP	Urocanate hydratase
CAI18_10600	ENOG4105C84	Histidine ammonia-lyase
CAI18_10605	ENOG4105CI2	imidazolone-5-propionate hydrolase
CAI18_10645	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
CAI18_10650	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
CAI18_10655	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
CAI18_10665	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
CAI18_10680	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
CAI18_10685	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
CAI18_10690	ENOG4105CC0	LysR family Transcriptional regulator
CAI18_10715	ENOG4105C8Q	Methyl-accepting chemotaxis
CAI18_10740	ENOG4105BZU	Histidine kinase
CAI18_10765	ENOG4105KWW	Biogenesis protein
CAI18_10770	ENOG4107QX9	Thiol disulfide interChange protein
CAI18_10775	ENOG4105DA4	cytochrome c-type biogenesis protein
CAI18_10780	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
CAI18_10790	ENOG41060IM	Heme exporter protein
CAI18_10805	ENOG4105EMN	RNA polymerase sigma factor
CAI18_10860	ENOG4105EGZ	biosynthesis protein
CAI18_10895	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
CAI18_10920	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CAI18_10925	ENOG4105BZ1	(ABC) transporter
CAI18_10930	ENOG41079KZ	Major Facilitator Superfamily
CAI18_10935	ENOG4105DEN	Luciferase family
CAI18_10965	ENOG4105CJ3	phosphate transporter
CAI18_10980	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CAI18_10990	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
CAI18_10995	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
CAI18_11005	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
CAI18_11010	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
CAI18_11015	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
CAI18_11020	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
CAI18_11025	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
CAI18_11030	ENOG4108DG9	Smr protein MutS2
CAI18_11035	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
CAI18_11040	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
CAI18_11045	ENOG4108UM1	dedA family
CAI18_11050	ENOG4108K5P	(LipO)protein
CAI18_11060	ENOG4105HBR	Rna-binding protein
CAI18_11065	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
CAI18_11070	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
CAI18_11075	ENOG4105EEI	dihydropteroate synthase
CAI18_11080	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
CAI18_11090	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
CAI18_11095	ENOG4107TH8	cina domain protein
CAI18_11105	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
CAI18_11110	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
CAI18_11120	ENOG4105Y3E	Modulates RecA activity (By similarity)
CAI18_11125	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
CAI18_11145	ENOG4107SDU	Methyl-accepting chemotaxis
CAI18_11155	ENOG4105CWB	LysR family transcriptional Regulator
CAI18_11195	ENOG4108IAB	Phoh family
CAI18_11200	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CAI18_11215	ENOG4107TUS	Dihydrodipicolinate synthase
CAI18_11225	ENOG4108Z4U	Ferredoxin
CAI18_11230	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
CAI18_11240	ENOG4105CXK	mandelate racemase muconate lactonizing
CAI18_11245	ENOG4108RTU	Aldolase
CAI18_11295	ENOG4105CMG	Carbohydrate kinase
CAI18_11300	ENOG4105C93	Xylose Isomerase
CAI18_11325	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
CAI18_11330	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
CAI18_11340	ENOG4105DJ0	Poly(A) Polymerase
CAI18_11345	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CAI18_11350	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
CAI18_11355	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
CAI18_11360	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
CAI18_11365	ENOG4107QP8	phosphohexose isomerase
CAI18_11415	ENOG4105KU2	hydrolase family 5
CAI18_11420	ENOG4108UYB	regulatoR
CAI18_11435	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
CAI18_11440	ENOG410841Q	phosphoesterase PA-phosphatase related protein
CAI18_11470	ENOG4105D4A	Cell wall formation (By similarity)
CAI18_11475	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
CAI18_11495	ENOG4105C26	Dehydrogenase
CAI18_11525	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
CAI18_11530	ENOG4106H78	methyltransferase
CAI18_11535	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
CAI18_11550	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
CAI18_11555	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
CAI18_11560	ENOG4105E08	Glycoside hydrolase, family 9
CAI18_11565	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
CAI18_11605	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
CAI18_11610	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
CAI18_11615	ENOG4105VIE	preprotein translocase, subunit YajC
CAI18_11620	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CAI18_11625	ENOG4107QT7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CAI18_11665	ENOG4105DM4	PTS System
CAI18_11670	ENOG4105DE4	1-phosphofructokinase
CAI18_11675	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
CAI18_11680	ENOG4108M60	Transcriptional regulator
CAI18_11690	ENOG4105BZS	acriflavin resistance protein
CAI18_11695	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
CAI18_11705	ENOG4105C7I	Dehydrogenase
CAI18_11740	ENOG4105W39	Membrane
CAI18_11755	ENOG4108RCM	Nitroreductase
CAI18_11760	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
CAI18_11795	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
CAI18_11885	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
CAI18_11890	ENOG41090A4	Pterin carbinolamine dehydratase
CAI18_11900	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
CAI18_11905	ENOG4108NST	exported protein
CAI18_11910	ENOG4105EI2	Pseudouridine synthase
CAI18_11915	ENOG4105C03	ribonuclease
CAI18_11925	ENOG4105C72	UPF0176 protein
CAI18_11935	ENOG4108V1T	peptidylprolyl cis-trans isomerase
CAI18_11945	ENOG4107QQG	Dehydrogenase
CAI18_11970	ENOG4105CEY	Amp-dependent synthetase and ligase
CAI18_12050	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
CAI18_12055	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
CAI18_12070	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
CAI18_12075	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
CAI18_12080	ENOG4105BZ1	(ABC) transporter
CAI18_12095	ENOG4108EC8	DNA internalization-related competence protein ComEC
CAI18_12105	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CAI18_12110	ENOG4105D60	lipoprotein releasing system transmembrane protein
CAI18_12120	ENOG410681N	tpr repeat protein
CAI18_12125	ENOG4105E33	succinate dehydrogenase
CAI18_12145	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
CAI18_12170	ENOG4105CHC	glucokinase (EC 2.7.1.2)
CAI18_12175	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
CAI18_12180	ENOG4105C01	Dihydroxy-acid dehydratase
CAI18_12185	ENOG4108UHU	Aldolase
CAI18_12215	ENOG4105N7H	Cytochrome
CAI18_12260	ENOG4105BZU	Histidine kinase
CAI18_12265	ENOG4105BZM	domain protein
CAI18_12290	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
CAI18_12300	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
CAI18_12320	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
CAI18_12350	ENOG4105XMH	SpoVT AbrB domain protein
CAI18_12465	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
CAI18_12470	ENOG4108Z6B	deaminase
CAI18_12475	ENOG4105KST	dependent repressor
CAI18_12480	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
CAI18_12500	ENOG4107SFI	Major Facilitator superfamily
CAI18_12525	ENOG4105CHJ	isochorismatase hydrolase
CAI18_12540	ENOG4105WH1	Two component transcriptional regulator luxr family
CAI18_12560	ENOG4105DND	Transcriptional regulator
CAI18_12570	ENOG4105EVH	UPF0753 protein
CAI18_12575	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
CAI18_12580	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
CAI18_12585	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
CAI18_12595	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
CAI18_12605	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
CAI18_12615	ENOG4105ESV	Glycosyl transferase, family 4
CAI18_12620	ENOG4105CFV	Tetratricopeptide repeat protein
CAI18_12630	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
CAI18_12635	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
CAI18_12640	ENOG4105CAT	Cytidine monophosphate kinase
CAI18_12660	ENOG4105DWY	Agmatine deiminase
CAI18_12690	ENOG4105DRS	transport system, permease
CAI18_12695	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
CAI18_12725	ENOG4105K9H	YciI-like protein
CAI18_12730	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
CAI18_12735	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
CAI18_12740	ENOG4105FE9	pseudouridine synthase
CAI18_12760	ENOG4105CHM	Aminotransferase
CAI18_12765	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
CAI18_12770	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
CAI18_12775	ENOG41060IM	Heme exporter protein
CAI18_12785	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
CAI18_12790	ENOG4105DA4	cytochrome c-type biogenesis protein
CAI18_12800	ENOG4105KWW	Biogenesis protein
CAI18_12820	ENOG4108JJ8	(ABC) transporter
CAI18_12825	ENOG4108JJ9	ABC, transporter
CAI18_12830	ENOG4105C4M	(Ubiquinol oxidase) subunit I
CAI18_12835	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
CAI18_12845	ENOG4105EKQ	RNA-directed DNA polymerase
CAI18_12870	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
CAI18_12875	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
CAI18_12885	ENOG4105CH7	arginosuccinase
CAI18_12890	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
CAI18_12900	ENOG4105CAS	nag kinase
CAI18_12915	ENOG4105CDH	Citrulline--aspartate ligase
CAI18_12920	ENOG4105DBV	ornithine carbamoyltransferase
CAI18_12930	ENOG4105C8N	cysteinyl-tRNA synthetase
CAI18_12935	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
CAI18_12950	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
CAI18_12955	ENOG4105CD3	dihydroorotase
CAI18_12980	ENOG4105CPD	ethanolamine ammonia-lyase
CAI18_12985	ENOG4107FQ9	ethanolamine ammonia-lyase
CAI18_13050	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
CAI18_13055	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
CAI18_13060	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
CAI18_13070	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
CAI18_13075	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
CAI18_13080	ENOG4105BZU	Histidine kinase
CAI18_13095	ENOG4105ECY	inositol monophosphatase
CAI18_13100	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
CAI18_13120	ENOG4105C5H	ABC transporter
CAI18_13125	ENOG4105C1J	atp-dependent rna helicase
CAI18_13130	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
CAI18_13135	ENOG4105CNG	UPF0061 protein
CAI18_13145	ENOG4108RXX	maleylacetoacetate isomerase
CAI18_13150	ENOG4105VEQ	Cold shock protein
CAI18_13155	ENOG4108VWS	Yaeq family
CAI18_13160	ENOG4105CBX	hi0933 family
CAI18_13195	ENOG4108C33	Resolvase
CAI18_13205	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
CAI18_13235	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
CAI18_13240	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
CAI18_13245	ENOG4105K8N	protein family UPF0079, ATPase
CAI18_13250	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
CAI18_13255	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
CAI18_13260	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
CAI18_13275	ENOG4105E6M	Sulphatase-modifying factor protein
CAI18_13315	ENOG4108V3W	Chemotaxis protein, CheW
CAI18_13320	ENOG4105C8Q	Methyl-accepting chemotaxis
CAI18_13325	ENOG4108VX5	3-methyladenine DNA glycosylase
CAI18_13330	ENOG4107QRT	dEAD DEAH box helicase
CAI18_13350	ENOG4105KB2	stringent starvation protein b
CAI18_13355	ENOG4107MKT	Stringent starvation protein a
CAI18_13360	ENOG4105EIX	cytochrome c1
CAI18_13365	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
CAI18_13380	ENOG4105E4C	Lytic transglycosylase catalytic
CAI18_13395	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
CAI18_13400	ENOG4105C9A	Phoh family
CAI18_13410	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
CAI18_13420	ENOG4108JU5	Magnesium and cobalt efflux protein
CAI18_13440	ENOG4105D38	putrescine abc transporter
CAI18_13445	ENOG4105F38	ABC transporter, permease
CAI18_13450	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CAI18_13470	ENOG4107RUE	extracellular solute-binding protein family 1
CAI18_13475	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
CAI18_13490	ENOG4105CFQ	glutamine synthetase
CAI18_13495	ENOG4105CJP	fad dependent oxidoreductase
CAI18_13505	ENOG4105W3S	hemerythrin-like, metal-binding protein
CAI18_13510	ENOG4105CSH	Transporter
CAI18_13520	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
CAI18_13525	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
CAI18_13555	ENOG4106BRA	Membrane
CAI18_13560	ENOG4105BZU	Histidine kinase
CAI18_13565	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CAI18_13570	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
CAI18_13600	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
CAI18_13620	ENOG4108ZXC	Two component transcriptional regulator, luxr family
CAI18_13650	ENOG4108N8X	transition metal ion binding
CAI18_13690	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
CAI18_13700	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
CAI18_13715	ENOG4105CGK	Exodeoxyribonuclease III
CAI18_13755	ENOG4105D06	uba thif-type nad fad binding protein
CAI18_13765	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
CAI18_13770	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
CAI18_13775	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
CAI18_13785	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
CAI18_13795	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
CAI18_13815	ENOG4105CHU	acetyl-coa acetyltransferase
CAI18_13825	ENOG41082MI	Protein CrcB homolog
CAI18_13830	ENOG4105D1H	recombination factor protein RarA
CAI18_13840	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
CAI18_13850	ENOG4105CNU	cell division protein FtsK
CAI18_13855	ENOG4105C3M	thioredoxin reductase
CAI18_13875	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CAI18_13890	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
CAI18_13920	ENOG4105BZU	Histidine kinase
CAI18_13925	ENOG4105BZU	Histidine kinase
CAI18_13955	ENOG4108ZC9	flagellar basal-body rod protein flgc
CAI18_13960	ENOG410822I	Flagellar hook capping protein
CAI18_13965	ENOG4105BZE	flagellar hook protein, FlgE
CAI18_13975	ENOG4108KPB	Flagellar basal-body rod protein FlgF
CAI18_13985	ENOG4105CGA	flagellar basal-body rod protein FlgG
CAI18_13990	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
CAI18_13995	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
CAI18_14010	ENOG4105DTJ	flagellar hook-associated protein
CAI18_14020	ENOG4107W9T	flagellar hook-associated
CAI18_14025	ENOG4105MQ3	flagellar protein FliS
CAI18_14045	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CAI18_14050	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
CAI18_14095	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
CAI18_14100	ENOG4105CHR	reductase
CAI18_14140	ENOG4107RGC	Glycosyl transferase, family 2
CAI18_14145	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
CAI18_14150	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
CAI18_14155	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
CAI18_14165	ENOG4108JIR	Flagellum-specific ATP synthase
CAI18_14185	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
CAI18_14190	ENOG4105DD5	Flagellar motor switch protein
CAI18_14200	ENOG4105CN7	Flagellar biosynthetic protein FliP
CAI18_14205	ENOG4105VS8	Flagellar biosynthetic protein fliq
CAI18_14210	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
CAI18_14215	ENOG4105BZU	Histidine kinase
CAI18_14235	ENOG4105D00	flagellar biosynthetic protein flhB
CAI18_14240	ENOG4105D7B	Flagellar biosynthesis protein flha
CAI18_14245	ENOG4105FZW	flagellar biosynthesis regulator FlhF
CAI18_14255	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CAI18_14260	ENOG4108VYJ	response regulator receiver protein
CAI18_14280	ENOG4105C4X	radical SAM domain protein
CAI18_14315	ENOG4105E14	MotA TolQ exbB proton channel
CAI18_14320	ENOG4105ER2	Ompa motb domain protein
CAI18_14330	ENOG4108V3W	Chemotaxis protein, CheW
CAI18_14340	ENOG4108VYJ	response regulator receiver protein
CAI18_14345	ENOG4105CBS	Chea signal transduction histidine kinase
CAI18_14350	ENOG4105C8Q	Methyl-accepting chemotaxis
CAI18_14365	ENOG4105C8Q	Methyl-accepting chemotaxis
CAI18_14380	ENOG4105C8Q	Methyl-accepting chemotaxis
CAI18_14385	ENOG4105C8Q	Methyl-accepting chemotaxis
CAI18_14395	ENOG4105C8Q	Methyl-accepting chemotaxis
CAI18_14400	ENOG4105C8Q	Methyl-accepting chemotaxis
CAI18_14410	ENOG4105C8Q	Methyl-accepting chemotaxis
CAI18_14415	ENOG4105C8Q	Methyl-accepting chemotaxis
CAI18_14420	ENOG4105C8Q	Methyl-accepting chemotaxis
CAI18_14425	ENOG4105C8Q	Methyl-accepting chemotaxis
CAI18_14430	ENOG4105C8Q	Methyl-accepting chemotaxis
CAI18_14440	ENOG4108V3W	Chemotaxis protein, CheW
CAI18_14450	ENOG4105C8Q	Methyl-accepting chemotaxis
CAI18_14455	ENOG4105BZU	Histidine kinase
CAI18_14460	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
CAI18_14465	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
CAI18_14470	ENOG4105BZU	Histidine kinase
CAI18_14475	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
CAI18_14480	ENOG4107QIJ	Aconitate hydratase 2
CAI18_14495	ENOG4107QM5	aconitate hydratase
CAI18_14505	ENOG4105CEY	Amp-dependent synthetase and ligase
CAI18_14540	ENOG4105E39	Enoyl-CoA hydratase
CAI18_14545	ENOG4105BZU	Histidine kinase
CAI18_14550	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CAI18_14555	ENOG4105CRK	lysyL-tRNA synthetase
CAI18_14565	ENOG4105DY9	regulatoR
CAI18_14615	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
CAI18_14625	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
CAI18_14630	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
CAI18_14640	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
CAI18_14645	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
CAI18_14650	ENOG4108RPX	mosc domain containing protein
CAI18_14670	ENOG4105CE1	Ferrous iron transport protein b
CAI18_14690	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
CAI18_14700	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
CAI18_14720	ENOG4105CQB	FAD linked oxidase domain protein
CAI18_14725	ENOG4108JQ1	Dehydrogenase
CAI18_14735	ENOG4105CUB	amino acid
CAI18_14740	ENOG4105CUB	amino acid
CAI18_14745	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
CAI18_14750	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
CAI18_14755	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
CAI18_14770	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
CAI18_14775	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
CAI18_14780	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
CAI18_14785	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
CAI18_14790	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
CAI18_14795	ENOG4105CIH	Imidazole acetol-phosphate transaminase
CAI18_14800	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
CAI18_14805	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
CAI18_14815	ENOG4105CUT	histidyl-tRNA synthetase
CAI18_14820	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
CAI18_14915	ENOG4107BJW	polysaccharide deacetylase
CAI18_15060	ENOG4107QTZ	amino acid
CAI18_15080	ENOG4105DC7	peptidase M24
CAI18_15090	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
CAI18_15105	ENOG41080HI	glycine oxidase
CAI18_15110	ENOG4105CTU	Proline racemase
CAI18_15120	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CAI18_15130	ENOG4105CEN	a g-specific adenine glycosylase
CAI18_15135	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
CAI18_15140	ENOG4105CQZ	Histidine kinase
CAI18_15185	ENOG4105QNF	Outer membrane lipoprotein
CAI18_15200	ENOG4105CSU	acyl-Coa dehydrogenase
CAI18_15210	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
CAI18_15230	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
CAI18_15235	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
CAI18_15240	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
CAI18_15265	ENOG4108NQK	Catalyzes the transfer of a glucuronic acid (GlcA) residue from UDP-glucuronate to mannose-alpha-1,3-glucose-beta- 1,4-glucose-P-P-polyisoprenyl to form the lipid-linked tetrasaccharide GlcA-Man-Glc(2)-PP-Pol, with a glucuronic acid- beta-mannose linkage. Is involved in the biosynthesis of the exopolysaccharide xanthan, since it catalyzes the fourth glycosylation step in the assembly of the pentasaccharide-P-P- polyisoprenyl repeating unit of xanthan. Is unable to use the trisaccharide acceptor freed from the pyrophosphate lipid moiety. Does not show specificity for the lipidic portion of the acceptor. Shows diminished activity when tested with 6-O-acetyl-mannose- alpha-1,3-glucose-beta-1,4-glucose-P-P-polyisoprenyl, a
CAI18_15275	ENOG4107Y2G	Glycosyl transferase (Group 1
CAI18_15300	ENOG4105D3Q	Sugar transferase
CAI18_15320	ENOG4105WJX	transcriptional regulator MERR family
CAI18_15330	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
CAI18_15335	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
CAI18_15350	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
CAI18_15355	ENOG4105C22	threonyL-tRNA synthetase
CAI18_15360	ENOG4105ETE	Transcriptional regulator (LacI family
CAI18_15405	ENOG4105CMA	conjugation trbi family protein
CAI18_15445	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
CAI18_15500	ENOG4105EWT	decarboxylase family
CAI18_15505	ENOG4108KPZ	tonB-dependent Receptor
CAI18_15515	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
CAI18_15525	ENOG4105M2J	Glutaredoxin
CAI18_15530	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
CAI18_15535	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
CAI18_15540	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
CAI18_15550	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
CAI18_15560	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
CAI18_15570	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
CAI18_15575	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
CAI18_15580	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
CAI18_15585	ENOG4105CHV	Transcription elongation factor NusA
CAI18_15590	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
CAI18_15600	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CAI18_15605	ENOG4105C8S	subunit m
CAI18_15610	ENOG4105D65	subunit l
CAI18_15625	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CAI18_15630	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
CAI18_15635	ENOG4107R0R	NADH dehydrogenase subunit g
CAI18_15640	ENOG4107QIZ	NADH dehydrogenase
CAI18_15645	ENOG4105GKE	subunit e
CAI18_15650	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CAI18_15655	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CAI18_15660	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CAI18_15665	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CAI18_15680	ENOG4105CP7	Triose-phosphate isomerase
CAI18_15685	ENOG4107FW0	short-chain dehydrogenase reductase
CAI18_15700	ENOG4105BZU	Histidine kinase
CAI18_15715	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
CAI18_15720	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
CAI18_15725	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
CAI18_15735	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
CAI18_15745	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
CAI18_15750	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
CAI18_15775	ENOG4105C5I	Dehydrogenase
CAI18_15780	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
CAI18_15785	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
CAI18_15795	ENOG4105DJ4	phosphatidylserine decarboxylase
CAI18_15810	ENOG4105D7A	ATP-binding protein
CAI18_15815	ENOG4107VIJ	nudix hydrolase
CAI18_15835	ENOG4108RRZ	Transcription elongation factor GreB
CAI18_15840	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
CAI18_15855	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
CAI18_15885	ENOG4105ED4	portal protein
CAI18_15930	ENOG4105NVB	glycoside hydrolase, family 19
CAI18_16135	ENOG4105DHP	deoxycytidine triphosphate deaminase
CAI18_16170	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
CAI18_16180	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
CAI18_16185	ENOG4105VEJ	Heat shock protein
CAI18_16200	ENOG4107QJQ	Mate efflux family protein
CAI18_16205	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
CAI18_16210	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
CAI18_16215	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
CAI18_16220	ENOG4105K5M	30s ribosomal protein S16
CAI18_16230	ENOG4107QWG	2-Nitropropane dioxygenase
CAI18_16235	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CAI18_16240	ENOG4105CRE	cytochrome C
CAI18_16245	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
CAI18_16250	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
CAI18_16280	ENOG4105BZU	Histidine kinase
CAI18_16285	ENOG4105BZU	Histidine kinase
CAI18_16290	ENOG4107Z5C	methylesterase
CAI18_16295	ENOG4105C08	Histidine kinase
CAI18_16300	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
CAI18_16325	ENOG4105BZU	Histidine kinase
CAI18_16335	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
CAI18_16340	ENOG4105FUA	antagonist
CAI18_16345	ENOG4107MMM	Anti-sigma-factor antagonist
CAI18_16355	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
CAI18_16370	ENOG4105KAF	membrAne
CAI18_16375	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
CAI18_16385	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
CAI18_16390	ENOG4105CCU	oxidase (Subunit III)
CAI18_16395	ENOG4105BZ9	Cytochrome C oxidase, subunit I
CAI18_16400	ENOG4105E2S	oxidase) subunit II
CAI18_16410	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
CAI18_16415	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
CAI18_16420	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
CAI18_16425	ENOG4105DTN	riboflavin biosynthesis protein ribF
CAI18_16430	ENOG4105CJR	Integral membrane protein (MviN
CAI18_16440	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CAI18_16445	ENOG4105K46	50S ribosomal protein l27
CAI18_16450	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
CAI18_16455	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
CAI18_16460	ENOG4108TGP	Thioesterase superfamily protein
CAI18_16510	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
CAI18_16520	ENOG4107SPG	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
CAI18_16565	ENOG4105WH1	Two component transcriptional regulator luxr family
CAI18_16570	ENOG4105BZU	Histidine kinase
CAI18_16585	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
CAI18_16590	ENOG4107QMS	site-determining protein
CAI18_16605	ENOG4105DHQ	Histidine kinase
CAI18_16610	ENOG4105ETX	regulatoR
CAI18_16625	ENOG4105DIJ	Phosphoethanolamine transferase
CAI18_16640	ENOG4105C2C	drug resistance transporter, Bcr CflA
CAI18_16645	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CAI18_16650	ENOG4105EBR	Carboxylesterase
CAI18_16655	ENOG4105CV8	reductase
CAI18_16685	ENOG4106AXJ	AraC family transcriptional regulator
CAI18_16745	ENOG4105C3M	thioredoxin reductase
CAI18_16755	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
CAI18_16760	ENOG4105CWX	Alpha-1,2-mannosidase
CAI18_16770	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
CAI18_16775	ENOG4105BZP	glycoside hydrolase 15-related
CAI18_16785	ENOG4107Z4K	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
CAI18_16825	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
CAI18_16850	ENOG4107XZC	Restriction modification system DNA (Specificity
CAI18_16880	ENOG4108XFH	Transcriptional regulator
CAI18_16885	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
CAI18_16890	ENOG4105CD8	aminopeptidase N
CAI18_16895	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
CAI18_16905	ENOG4105EPW	hflc protein
CAI18_16910	ENOG4107QJR	hflk protein
CAI18_16915	ENOG4105M3Z	response regulator
CAI18_16940	ENOG4108JQB	penicillin-binding protein 1C
CAI18_16960	ENOG4105DN3	alpha-2-macroglobulin domain protein
CAI18_16980	ENOG4105C7F	AcnD-accessory protein PrpF
CAI18_16995	ENOG4105YAJ	CopG Arc MetJ
CAI18_17000	ENOG4108I0Z	Aconitate hydratase
CAI18_17005	ENOG4105BZN	citrate synthase
CAI18_17010	ENOG4105CR4	methylisocitrate lyase
CAI18_17015	ENOG4108JU7	Transcriptional regulator
CAI18_17035	ENOG4107QRG	dna polymerase iii
CAI18_17040	ENOG4105HHA	aminodeoxychorismate lyase
CAI18_17050	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
CAI18_17060	ENOG4105CHR	reductase
CAI18_17065	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
CAI18_17075	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
CAI18_17080	ENOG4105VGS	50s ribosomal protein l32
CAI18_17085	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
CAI18_17090	ENOG4108UHJ	MAF-like protein
CAI18_17120	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
CAI18_17130	ENOG4105F8C	transglutaminase domain-containing protein
CAI18_17140	ENOG4105K59	histidine triad (HIT) protein
CAI18_17145	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
CAI18_17150	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
CAI18_17155	ENOG4107QMP	dna polymerase iii subunits gamma and tau
CAI18_17170	ENOG4108ZAF	Molybdopterin
CAI18_17175	ENOG4105M00	molybdopterin converting factor, subunit 1
CAI18_17180	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
CAI18_17185	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
CAI18_17190	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
CAI18_17195	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
CAI18_17200	ENOG4105DKP	glycosyl transferase, family 9
CAI18_17215	ENOG4108ZF3	Phosphatase
CAI18_17220	ENOG4107RZZ	dna polymerase iii epsilon subunit
CAI18_17225	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CAI18_17235	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
CAI18_17240	ENOG41068JE	domain protein
CAI18_17245	ENOG4105EIN	peptidylprolyl cis-trans isomerase
CAI18_17270	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
CAI18_17280	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
CAI18_17290	ENOG4105BZU	Histidine kinase
CAI18_17320	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
CAI18_17330	ENOG4105VW4	glutaredoxin 3
CAI18_17335	ENOG4105ERG	peptidase m48, ste24p
CAI18_17340	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CAI18_17345	ENOG4105BZU	Histidine kinase
CAI18_17350	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
CAI18_17355	ENOG4105C9X	ppx gppa phosphatase
CAI18_17360	ENOG4105BZF	Glycosyl transferase (Group 1
CAI18_17365	ENOG4105EYK	Phosphatidylglycerophosphatase B
CAI18_17370	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
CAI18_17390	ENOG4105ED9	Protein of unknown function (DUF455)
CAI18_17395	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
CAI18_17410	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
CAI18_17420	ENOG4105CVJ	phosphoglycerate mutase
CAI18_17455	ENOG4105CPQ	Dehydrogenase
CAI18_17465	ENOG4108IJ6	ABC transporter
CAI18_17475	ENOG4108I5D	sulfate abc transporter
CAI18_17480	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
CAI18_17485	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
CAI18_17495	ENOG4108R99	pseudouridine synthase
CAI18_17505	ENOG4105CDV	Ompa motb domain protein
CAI18_17520	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
CAI18_17540	ENOG4108K3A	Glutathione S-transferase
CAI18_17550	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
CAI18_17555	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
CAI18_17560	ENOG4105CI3	gtp-binding protein typa
CAI18_17570	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
CAI18_17580	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
CAI18_17600	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
CAI18_17630	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
CAI18_17635	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
CAI18_17650	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
CAI18_17655	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
CAI18_17660	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
CAI18_17670	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CAI18_17675	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
CAI18_17700	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
CAI18_17710	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
CAI18_17715	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CAI18_17725	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
CAI18_17730	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
CAI18_17735	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
CAI18_17740	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
CAI18_17745	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
CAI18_17750	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
CAI18_17760	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CAI18_17765	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CAI18_17770	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
CAI18_17775	ENOG4108VZM	50s ribosomal protein L10
CAI18_17780	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
CAI18_17785	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
CAI18_17790	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
CAI18_17795	ENOG4105PM1	preprotein translocase subunit SecE
CAI18_17805	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
CAI18_17825	ENOG4105C3G	gtp-binding protein
CAI18_17830	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
CAI18_17835	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
CAI18_17840	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
CAI18_17850	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
CAI18_17855	ENOG4105QVB	outer membrane lipoprotein LolB
CAI18_17860	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
CAI18_17865	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
CAI18_17870	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
CAI18_17890	ENOG4105CSR	polyphosphate kinase 2
CAI18_17910	ENOG4107S2Z	UPF0761 membrane protein
CAI18_17915	ENOG4105CS1	NAD(P)H quinone oxidoreductase
CAI18_17935	ENOG4108Z66	YbaK ebsC protein
CAI18_17940	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
CAI18_17950	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
CAI18_17960	ENOG4105CM2	brancheD-chain amino acid aminotransferase
CAI18_17975	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
CAI18_17980	ENOG4105W8H	transhydrogenase (subunit alpha
CAI18_18000	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
CAI18_18030	ENOG4105C2M	dna polymerase I
CAI18_18050	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
CAI18_18065	ENOG4105C5Q	Transcriptional regulator
CAI18_18075	ENOG4105NXH	GreA GreB family elongation factor
CAI18_18080	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
CAI18_18090	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
CAI18_18105	ENOG4105BZU	Histidine kinase
CAI18_18125	ENOG4105CX6	glutaminyL-tRNA synthetase
CAI18_18135	ENOG4105DXC	membrane
CAI18_18155	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
CAI18_18190	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
CAI18_18200	ENOG4105CEY	Amp-dependent synthetase and ligase
CAI18_18205	ENOG4105DDW	LysR family Transcriptional regulator
CAI18_18240	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
CAI18_18245	ENOG4105D0A	hydroxylase
CAI18_18260	ENOG4108WBT	adenosyltransferase
CAI18_18270	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
CAI18_18275	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
CAI18_18280	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
CAI18_18285	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
CAI18_18290	ENOG4105NWN	ApaG protein
CAI18_18295	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
CAI18_18305	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CAI18_18315	ENOG4105DEF	Extracellular solute-binding protein, family 5
CAI18_18340	ENOG4108UZX	fmn reductase
CAI18_18345	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
CAI18_18355	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
CAI18_18360	ENOG4105D7T	ABC transporter
CAI18_18365	ENOG4107T8P	acyl-Coa dehydrogenase
CAI18_18370	ENOG4107SM7	Transcriptional regulator
CAI18_18385	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
CAI18_18390	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
CAI18_18425	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
CAI18_18430	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
CAI18_18440	ENOG4105EUB	pirin domain protein
CAI18_18455	ENOG4105EUB	pirin domain protein
CAI18_18460	ENOG4105D22	carbon starvation protein
CAI18_18465	ENOG4105VCD	cytoplasmic protein
CAI18_18515	ENOG4107XAN	XdhC and CoxI family
CAI18_18520	ENOG4105C7W	Xanthine dehydrogenase
CAI18_18525	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
CAI18_18530	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
CAI18_18545	ENOG4108UUM	single-stranded DNA-binding protein
CAI18_18550	ENOG4105EAH	synthase
CAI18_18565	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
CAI18_18580	ENOG4105CFH	Aspartokinase
CAI18_18585	ENOG4105JAB	phenazine biosynthesis protein, phzf family
CAI18_18600	ENOG4108Z9K	Osmotically inducible protein
CAI18_18605	ENOG4105CXT	aspartate transcarbamylase
CAI18_18610	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
CAI18_18615	ENOG4108UJU	UPF0301 protein
CAI18_18625	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
CAI18_18635	ENOG4108E16	pectate lyase
CAI18_18640	ENOG4105CZX	twitching motility protein
CAI18_18645	ENOG4105CZX	twitching motility protein
CAI18_18650	ENOG4105DFA	alanine racemase domain protein
CAI18_18655	ENOG4105II7	pyrroline-5-carboxylate reductase
CAI18_18665	ENOG4105FAA	peptidase M23
CAI18_18685	ENOG4108Z0Z	intracellular protease Pfpi family
CAI18_18705	ENOG4105C3K	feS assembly ATPase SufC
CAI18_18710	ENOG4105JRK	feS assembly protein SufD
CAI18_18715	ENOG4105C9B	Cysteine desulfurase
CAI18_18725	ENOG4105VQD	rieske 2fe-2S domain-containing protein
CAI18_18730	ENOG4108IU3	tonb-dependent siderophore receptor
CAI18_18735	ENOG4107E2E	PKHD-type hydroxylase
CAI18_18760	ENOG4105CJ2	(LipO)protein
CAI18_18765	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
CAI18_18780	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
CAI18_18795	ENOG4105EHM	Aminoglycoside phosphotransferase
CAI18_18800	ENOG4108S0S	Nucleotidyl transferase
CAI18_18810	ENOG4105C02	permease
CAI18_18820	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
CAI18_18830	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
CAI18_18850	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
CAI18_18860	ENOG4105C2X	Arabinose 5-phosphate isomerase
CAI18_18865	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
CAI18_18875	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
CAI18_18880	ENOG4108IUZ	ABC transporter
CAI18_18885	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CAI18_18890	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
CAI18_18895	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
CAI18_18900	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
CAI18_18905	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
CAI18_18915	ENOG41080Z8	PHOSPHOCARRIER protein
CAI18_18920	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
CAI18_18930	ENOG4105CJW	magnesium transporter
CAI18_18935	ENOG4107UWA	esterase
CAI18_18945	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
CAI18_18950	ENOG4105C4M	(Ubiquinol oxidase) subunit I
CAI18_18970	ENOG4105C85	amino acid
CAI18_18980	ENOG4108NFF	pectate lyase
CAI18_19005	ENOG4105CUB	amino acid
CAI18_19025	ENOG4108MHS	Lysyl endopeptidase
CAI18_19035	ENOG4107XDQ	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
CAI18_19095	ENOG4108Z4X	TRANSCRIPTIONal
CAI18_19110	ENOG4106032	Glutathionylspermidine synthase
CAI18_19135	ENOG4108P9J	Phage shock protein A
CAI18_19145	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
CAI18_19150	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
CAI18_19155	ENOG4105D49	3-dehydroquinate synthase
CAI18_19165	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
CAI18_19170	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
CAI18_19175	ENOG4105BZU	Histidine kinase
CAI18_19180	ENOG4105BZU	Histidine kinase
CAI18_19190	ENOG4105BZU	Histidine kinase
CAI18_19195	ENOG4108YYC	ycei family
CAI18_19215	ENOG4105EJQ	L-serine dehydratase
CAI18_19230	ENOG4105CFH	Aspartokinase
CAI18_19235	ENOG4105C28	cystathionine
CAI18_19240	ENOG4106TYC	homoserine o-acetyltransferase (EC 2.3.1.31)
CAI18_19245	ENOG4105DR5	peptidase
CAI18_19250	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
CAI18_19255	ENOG4108UT2	hemolysin iii
CAI18_19260	ENOG41066T0	asmA family
CAI18_19265	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
CAI18_19275	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
CAI18_19280	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
CAI18_19305	ENOG4108IG5	Transcriptional regulator
CAI18_19315	ENOG4107QPN	acyl-Coa dehydrogenase
CAI18_19340	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
CAI18_19345	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
CAI18_19365	ENOG4105KK4	UPF0060 membrane protein
CAI18_19370	ENOG4105DXN	mazG family
CAI18_19375	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
CAI18_19380	ENOG4107RK2	ADP-ribose diphosphatase NudE
CAI18_19390	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
CAI18_19395	ENOG4105CHC	glucokinase (EC 2.7.1.2)
CAI18_19410	ENOG4105VRS	hydrolase family 18
CAI18_19430	ENOG4108JJA	ABC, transporter
CAI18_19460	ENOG4105CWX	Alpha-1,2-mannosidase
CAI18_19500	ENOG4106N3A	copper homeostasis protein cutc
CAI18_19520	ENOG4105D9U	N-acetyltransferase
CAI18_19540	ENOG4105C8Q	Methyl-accepting chemotaxis
CAI18_19550	ENOG4105M3Z	response regulator
CAI18_19555	ENOG4108UNF	response regulator
CAI18_19560	ENOG4105D7Z	glutathione synthase
CAI18_19570	ENOG41065RQ	ADP-ribosylation crystallin J1
CAI18_19575	ENOG41072GX	Peptidase M22 Glycoprotease
CAI18_19580	ENOG4105DVT	helicase
CAI18_19590	ENOG4105BZ4	penicillin-binding protein
CAI18_19620	ENOG410698T	Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide (By similarity)
CAI18_19625	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
CAI18_19630	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
CAI18_19635	ENOG4105Z85	coenzyme PQQ synthesis
CAI18_19640	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
CAI18_19665	ENOG4105CQ7	ATP-dependent helicase
CAI18_19680	ENOG4105C9U	ATP-dependent DNA helicase RecQ
CAI18_19715	ENOG4105C8Q	Methyl-accepting chemotaxis
CAI18_19735	ENOG410903D	sensor protein
CAI18_19740	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
CAI18_19750	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
CAI18_19760	ENOG4105KCK	Peptidoglycan-associated lipoprotein
CAI18_19765	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
CAI18_19780	ENOG4105E02	MotA TolQ exbB proton channel
CAI18_19785	ENOG4107YD3	Thioesterase
CAI18_19790	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
CAI18_19800	ENOG4105DFH	Transport of potassium into the cell (By similarity)
CAI18_19805	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
CAI18_19810	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
CAI18_19815	ENOG4105CDY	transcriptional regulatory protein
CAI18_19830	ENOG4105C9M	aspartyl-trna synthetase
CAI18_19845	ENOG4108ISG	Major Facilitator
CAI18_19860	ENOG4105HSS	phospholipase C
CAI18_19880	ENOG4105ETT	transcriptional Regulator, LysR family
CAI18_19890	ENOG4105C5H	ABC transporter
CAI18_19895	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
CAI18_19915	ENOG4107RNH	Outer membrane receptor FepA
CAI18_19930	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
CAI18_19955	ENOG4105GAV	receptor
CAI18_19980	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
CAI18_20010	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
CAI18_20015	ENOG4108YZT	Adenosylcobinamide kinase
CAI18_20020	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
CAI18_20025	ENOG4105EFT	decarboxylase
CAI18_20035	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
CAI18_20050	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
CAI18_20055	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CAI18_20060	ENOG4105E2Y	ABC, transporter
CAI18_20065	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
CAI18_20070	ENOG4105GVF	(ABC) transporter
CAI18_20075	ENOG4105CPC	Aldo Keto reductase
CAI18_20085	ENOG4107ZSV	Receptor
CAI18_20095	ENOG41082IR	Excinuclease ABC C subunit domain protein
CAI18_20130	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
CAI18_20140	ENOG4108K4C	ec 3.1.3.12
CAI18_20145	ENOG4105BZP	glycoside hydrolase 15-related
CAI18_20150	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
CAI18_20155	ENOG4105DZG	Dehydrogenase
CAI18_20165	ENOG4105C8Q	Methyl-accepting chemotaxis
CAI18_20170	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
CAI18_20185	ENOG4105C34	Pseudouridine synthase
CAI18_20190	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CAI18_20200	ENOG4105C4K	Nad synthetase
CAI18_20210	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
CAI18_20215	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
CAI18_20220	ENOG4107TUY	Histidine kinase
CAI18_20225	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CAI18_20235	ENOG4107QHF	type ii secretion system protein e
CAI18_20245	ENOG4107QHF	type ii secretion system protein e
CAI18_20260	ENOG4105D7Q	type ii secretion system
CAI18_20265	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
CAI18_20270	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
CAI18_20280	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
CAI18_20285	ENOG4108JJA	ABC, transporter
CAI18_20290	ENOG4105CHM	Aminotransferase
CAI18_20340	ENOG41069H0	dihydroorotase EC 3.5.2.3
CAI18_20345	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
CAI18_20380	ENOG4108RMV	DegV Family
CAI18_20385	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
CAI18_20415	ENOG4105EJG	cellulose synthase
CAI18_20420	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
CAI18_20425	ENOG4107EEX	Cellulose synthase regulator protein
CAI18_20430	ENOG4107QZ7	Cellulose synthase catalytic subunit
CAI18_20445	ENOG4107RH7	Nicotinate phosphoribosyltransferase
CAI18_20510	ENOG4106S9K	Transcriptional regulator
CAI18_20525	ENOG4105GVR	general secretion pathway protein D
CAI18_20535	ENOG410678M	general secretion pathway protein M
CAI18_20540	ENOG41090VX	general secretion pathway protein L
CAI18_20545	ENOG4105UV2	general secretion pathway protein K
CAI18_20550	ENOG41069G9	General secretion pathway protein J
CAI18_20560	ENOG4105WMT	general secretion pathway protein h
CAI18_20570	ENOG4105D7Q	type ii secretion system
CAI18_20580	ENOG4107QHF	type ii secretion system protein e
CAI18_20585	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
CAI18_20590	ENOG4105EUR	Domain-Containing protein
CAI18_20595	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
CAI18_20600	ENOG4105EUR	Domain-Containing protein
CAI18_20605	ENOG4108ETH	Formylglycinamide ribotide synthetase
CAI18_20615	ENOG4105T95	Thiol disulfide interChange protein
CAI18_20625	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CAI18_20640	ENOG4108K5H	permease YjgP YjgQ family protein
CAI18_20650	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
CAI18_20665	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
CAI18_20680	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
CAI18_20685	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
CAI18_20705	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
CAI18_20715	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
CAI18_20720	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
CAI18_20735	ENOG4105DHJ	ABC, transporter
CAI18_20740	ENOG4108SNX	Mammalian cell entry related domain protein
CAI18_20755	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
CAI18_20775	ENOG4107QKV	phosphomannomutase
CAI18_20780	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
CAI18_20790	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
CAI18_20795	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
CAI18_20810	ENOG4105BZJ	Electron transfer flavoprotein
CAI18_20815	ENOG4105C10	Electron transfer flavoprotein
CAI18_20830	ENOG4105IQ5	FAD linked oxidase domain protein
CAI18_20845	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
CAI18_20890	ENOG4105EY8	ABC transporter
CAI18_20900	ENOG4105C28	cystathionine
CAI18_20925	ENOG4105CZX	twitching motility protein
CAI18_20930	ENOG4108RXX	maleylacetoacetate isomerase
CAI18_20945	ENOG4105C1J	atp-dependent rna helicase
CAI18_20955	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
CAI18_20965	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
CAI18_20975	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
CAI18_20995	ENOG4105NIV	Esterase
CAI18_21000	ENOG4107RNH	Outer membrane receptor FepA
CAI18_21005	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
CAI18_21010	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
CAI18_21015	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
CAI18_21030	ENOG4105DGW	oligopeptidase A
CAI18_21045	ENOG4105E3B	Multicopper oxidase
CAI18_21085	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
CAI18_21090	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
CAI18_21095	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CAI18_21100	ENOG4107RBB	ABC transporter, permease
CAI18_21105	ENOG4107RBB	ABC transporter, permease
CAI18_21120	ENOG4105BZU	Histidine kinase
CAI18_21125	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
CAI18_21140	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
CAI18_21145	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
CAI18_21150	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
CAI18_21155	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
CAI18_21160	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CAI18_21165	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CAI18_21170	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CAI18_21175	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
CAI18_21195	ENOG4107QN2	dihydrolipoyl dehydrogenase
CAI18_21205	ENOG4107QSN	dihydrolipoamide acetyltransferase
CAI18_21245	ENOG4105D01	(LipO)protein
CAI18_21250	ENOG4108UMI	ABC transporter, permease
CAI18_21255	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
CAI18_21260	ENOG4108EHX	EamA-like transporter family
CAI18_21265	ENOG4108VPT	UPF0234 protein
CAI18_21275	ENOG4105BZU	Histidine kinase
CAI18_21295	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
CAI18_21300	ENOG4107YBY	Hydrolase
CAI18_21305	ENOG4105I08	Pseudouridine synthase
CAI18_21310	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
CAI18_21330	ENOG4105BZU	Histidine kinase
CAI18_21350	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
CAI18_21355	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
CAI18_21360	ENOG4105EW9	transcriptional regulator AsnC family
CAI18_21380	ENOG4107RD7	Flagellar Motor Protein, MotA
CAI18_21385	ENOG4105ER2	Ompa motb domain protein
CAI18_21415	ENOG4105E3A	(ABC) transporter
CAI18_21420	ENOG4105DA5	(ABC) transporter
CAI18_21425	ENOG4105EEQ	Na H antiporter
CAI18_21440	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
CAI18_21450	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
CAI18_21470	ENOG4105CPC	Aldo Keto reductase
CAI18_21480	ENOG4106WTF	Glycosyl transferase, family 2
CAI18_21485	ENOG4105C9K	Endothelin-converting enzyme 1
CAI18_21505	ENOG4107QTZ	amino acid
CAI18_21515	ENOG4108VAC	response regulator
CAI18_21520	ENOG4105C2F	Histidine kinase
CAI18_21545	ENOG4108Z9Z	response to DNA damage stimulus
CAI18_21550	ENOG4105WEF	catalase
CAI18_21570	ENOG4105BZU	Histidine kinase
CAI18_21585	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CAI18_21600	ENOG4105C4M	(Ubiquinol oxidase) subunit I
CAI18_21605	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
CAI18_21625	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
CAI18_21630	ENOG4105CMR	udp-glucose 4-epimerase
CAI18_21660	ENOG4105BZ1	(ABC) transporter
CAI18_21685	ENOG4105E2A	Dehydrogenase
CAI18_21745	ENOG4105CIG	ABC transporter
CAI18_21760	ENOG4108UQ8	endoribonuclease L-psp
CAI18_21775	ENOG4105C8Q	Methyl-accepting chemotaxis
CAI18_21790	ENOG4105HEI	LysR family (Transcriptional regulator
CAI18_21795	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
CAI18_21870	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CAI18_21875	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
CAI18_21880	ENOG4105D1S	lipid A biosynthesis
CAI18_21890	ENOG4108Z7F	N-acetyltransferase
CAI18_21935	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
CAI18_21940	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
CAI18_21945	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
CAI18_21950	ENOG4108WZM	domain protein
CAI18_21955	ENOG4105C79	DNA protecting protein DprA
CAI18_21975	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
CAI18_21980	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CAI18_21995	ENOG4107ZQV	short-chain dehydrogenase reductase
CAI18_22010	ENOG4105D07	Signal peptide peptidase, SppA
CAI18_22015	ENOG4107QI1	Mate efflux family protein
CAI18_22035	ENOG4105C25	Primosomal protein n'
CAI18_22040	ENOG4108TGY	Glutathione S-transferase
CAI18_22065	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CAI18_22070	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
CAI18_22075	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CAI18_22080	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
CAI18_22085	ENOG4105CAK	Cell division ATP-binding protein ftsE
CAI18_22090	ENOG4105C1J	atp-dependent rna helicase
CAI18_22100	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
CAI18_22105	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
CAI18_22110	ENOG4105ETT	transcriptional Regulator, LysR family
CAI18_22120	ENOG4105E9K	Isocitrate dehydrogenase
CAI18_22135	ENOG4105FB9	CRISPR-associated protein
CAI18_22155	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
CAI18_22160	ENOG4105KCF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
CAI18_22170	ENOG4109066	lysm domain bon superfamily protein
CAI18_22175	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
CAI18_22180	ENOG4105CH2	amidohydrolase
CAI18_22185	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
CAI18_22190	ENOG4105BZS	acriflavin resistance protein
CAI18_22200	ENOG4105E32	cytoplasmic protein
CAI18_22250	ENOG4108UQS	dipeptidase
CAI18_22255	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
CAI18_22265	ENOG4105DTQ	mandelate racemase muconate lactonizing
CAI18_22275	ENOG4105D5Q	Arginine ornithine antiporter
CAI18_22290	ENOG4108Z12	YiaAB two helix domain-containing protein
CAI18_22300	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
CAI18_22305	ENOG4107ZVW	dihydroneopterin aldolase
CAI18_22310	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CAI18_22320	ENOG4105KTH	gatB Yqey
CAI18_22330	ENOG4107S2Z	UPF0761 membrane protein
CAI18_22335	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
CAI18_22340	ENOG4105DHU	Bile acid
CAI18_22350	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
CAI18_22375	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
CAI18_22380	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
CAI18_22395	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
CAI18_22405	ENOG4105C26	Dehydrogenase
CAI18_22435	ENOG4105DKK	Benzoate
CAI18_22455	ENOG4105DSB	aldose 1-epimerase
CAI18_22465	ENOG4105K5B	UPF0225 protein
CAI18_22470	ENOG4105EJ9	Membrane
CAI18_22490	ENOG4105EUJ	GTP cyclohydrolase i
CAI18_22500	ENOG4105ZQC	membrane protein AaeX
CAI18_22505	ENOG4105Y49	secretion protein, HlyD family
CAI18_22515	ENOG4105DR8	Membrane
CAI18_22520	ENOG4105CSH	Transporter
CAI18_22530	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
CAI18_22575	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
CAI18_22585	ENOG4108SIC	Transcriptional regulator
CAI18_22700	ENOG4105F2I	Transposase
CAI18_22720	ENOG4107QKA	exodeoxyribonuclease V beta
CAI18_22725	ENOG4105DSY	exodeoxyribonuclease V, gamma
CAI18_22740	ENOG4105DHJ	ABC, transporter
CAI18_22745	ENOG4105CY3	ABC transporter, permease
CAI18_22750	ENOG4107PE3	Mammalian cell entry related domain protein
CAI18_22765	ENOG410903C	(LipO)protein
CAI18_22775	ENOG4108V06	Glutathione peroxidase
CAI18_22785	ENOG4107QSV	RmuC domain protein
CAI18_22790	ENOG4105CIS	alcohol dehydrogenase
CAI18_22795	ENOG4105EJC	lysr family transcriptional regulator
CAI18_22810	ENOG4108TGY	Glutathione S-transferase
CAI18_22820	ENOG4105CUB	amino acid
CAI18_22835	ENOG4105NRM	Membrane
CAI18_22865	ENOG4105DR4	Methyltransferase
CAI18_22875	ENOG4105DU1	integral membrane protein, terc
CAI18_22890	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
CAI18_22905	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
CAI18_22910	ENOG4108ZJ4	polysaccharide deacetylase
CAI18_22915	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CAI18_22920	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
CAI18_22980	ENOG4106RHG	Yeca family
CAI18_23210	ENOG4105CMA	conjugation trbi family protein
CAI18_23325	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
CAI18_23430	ENOG4106RHG	Yeca family
CAI18_23445	ENOG4105C26	Dehydrogenase
CAI18_23510	ENOG4108NSC	Pfam:DUF88
CAI18_23570	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
CAI18_23645	ENOG4105C26	Dehydrogenase
CAI18_23685	ENOG4105C0H	protease