locus-tag	class	description
XapA_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
XapA_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
XapA_00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
XapA_00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
XapA_00030	ENOG4108K0D	peptidase, M48
XapA_00060	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
XapA_00070	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
XapA_00105	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
XapA_00125	ENOG4105CN1	protease
XapA_00130	ENOG41063SB	peptidase
XapA_00140	ENOG4107VAM	peptidase, m28
XapA_00180	ENOG4105DQ4	alcohol dehydrogenase
XapA_00185	ENOG4105BZ8	glutamate synthase
XapA_00190	ENOG4105CBC	glutamate synthase
XapA_00220	ENOG4105EXG	Transcriptional regulator
XapA_00240	ENOG4105D3Q	Sugar transferase
XapA_00245	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
XapA_00270	ENOG4107RA4	Glycosyl transferase (Group 1
XapA_00305	ENOG4105CMR	udp-glucose 4-epimerase
XapA_00320	ENOG4105BZ1	(ABC) transporter
XapA_00350	ENOG4107W2Z	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) (By similarity)
XapA_00450	ENOG4108I5C	dEAD DEAH box helicase
XapA_00455	ENOG4108UT2	hemolysin iii
XapA_00475	ENOG4107FW0	short-chain dehydrogenase reductase
XapA_00480	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
XapA_00495	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
XapA_00530	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
XapA_00540	ENOG4105CSH	Transporter
XapA_00545	ENOG4105DR8	Membrane
XapA_00555	ENOG4105Y49	secretion protein, HlyD family
XapA_00560	ENOG4105ZQC	membrane protein AaeX
XapA_00570	ENOG4105EUJ	GTP cyclohydrolase i
XapA_00590	ENOG4105EJ9	Membrane
XapA_00595	ENOG4105K5B	UPF0225 protein
XapA_00605	ENOG4105DSB	aldose 1-epimerase
XapA_00630	ENOG4105DKK	Benzoate
XapA_00660	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
XapA_00680	ENOG4105C4R	Atp-dependent dna helicase
XapA_00685	ENOG4105KNA	-acetyltransferase
XapA_00695	ENOG4108YXG	UPF0502 protein
XapA_00705	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
XapA_00710	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
XapA_00715	ENOG4105QV4	Tryptophan halogenase
XapA_00730	ENOG4105ETE	Transcriptional regulator (LacI family
XapA_00745	ENOG4105E55	glycerol-3-phosphate acyltransferase
XapA_00780	ENOG4105RKW	reductase (By
XapA_00865	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
XapA_00870	ENOG4105CG3	alpha amylase, catalytic region
XapA_00875	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
XapA_00890	ENOG4105EBR	Carboxylesterase
XapA_00905	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
XapA_00915	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
XapA_00920	ENOG4105DSG	hydrolase family 43
XapA_00925	ENOG4105ETE	Transcriptional regulator (LacI family
XapA_00935	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
XapA_00940	ENOG4105CHR	reductase
XapA_00950	ENOG4107TDE	lipolytic protein G-D-S-L family
XapA_00965	ENOG4105MIR	Phenylalanine 4-monooxygenase
XapA_00970	ENOG4108YXU	transcriptional regulator AsnC family
XapA_00975	ENOG4105CNM	Receptor
XapA_00980	ENOG4105D78	K07001 NTE family protein
XapA_00990	ENOG4105DKW	ABC transporter
XapA_01005	ENOG4108IJ8	ABC transporter
XapA_01010	ENOG4105E90	ABC transporter
XapA_01075	ENOG4105D1F	ATP-binding protein
XapA_01080	ENOG4105M4E	phosphohistidine phosphatase, SixA
XapA_01090	ENOG4107RZC	phospholipase d
XapA_01100	ENOG4105KA0	thioesterase Superfamily protein
XapA_01140	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
XapA_01150	ENOG4105C5F	glutamine synthetase
XapA_01160	ENOG4105BZU	Histidine kinase
XapA_01165	ENOG4105CUX	Signal transduction histidine kinase
XapA_01170	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
XapA_01175	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
XapA_01180	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
XapA_01195	ENOG4105CHU	acetyl-coa acetyltransferase
XapA_01230	ENOG4107YZP	Rhodanese domain protein
XapA_01235	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
XapA_01240	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
XapA_01295	ENOG4105D00	flagellar biosynthetic protein flhB
XapA_01300	ENOG4105D7B	Flagellar biosynthesis protein flha
XapA_01305	ENOG4108JQA	flagellar
XapA_01310	ENOG4105CGA	flagellar basal-body rod protein FlgG
XapA_01320	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
XapA_01325	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
XapA_01340	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
XapA_01345	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
XapA_01385	ENOG410822I	Flagellar hook capping protein
XapA_01390	ENOG4105BZE	flagellar hook protein, FlgE
XapA_01400	ENOG4105DD5	Flagellar motor switch protein
XapA_01410	ENOG4105CN7	Flagellar biosynthetic protein FliP
XapA_01415	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
XapA_01420	ENOG4105C7K	acetolactate synthase
XapA_01425	ENOG4108TQ9	Histidine kinase
XapA_01430	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
XapA_01450	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
XapA_01465	ENOG4105E2T	synthase III
XapA_01470	ENOG4107R3N	Filamentation induced by cAMP protein fic
XapA_01475	ENOG4108J2P	Alpha beta hydrolase fold
XapA_01480	ENOG4105PI0	Ferredoxin
XapA_01485	ENOG410680H	amp-dependent synthetase and ligase
XapA_01490	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
XapA_01505	ENOG4105CPF	Cell wall formation (By similarity)
XapA_01515	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
XapA_01525	ENOG4105DR9	pseudouridine synthase
XapA_01535	ENOG4108YZN	class I peptide chain release factor
XapA_01545	ENOG4105D44	asparaginase
XapA_01550	ENOG4105DGW	oligopeptidase A
XapA_01585	ENOG4107R11	Transcriptional regulator
XapA_01590	ENOG4107QP3	malate synthase g
XapA_01600	ENOG4105BZU	Histidine kinase
XapA_01640	ENOG4107QX3	carboxylase
XapA_01645	ENOG4105C1G	acyl-Coa dehydrogenase
XapA_01650	ENOG4108RZE	Tetr family transcriptional regulator
XapA_01705	ENOG4105CKI	cobalamin synthesis protein
XapA_01725	ENOG4105D6Z	AFG1 family ATPase
XapA_01730	ENOG4105K56	Transcriptional regulator
XapA_01735	ENOG4108ZHJ	Organic hydroperoxide resistance protein
XapA_01765	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
XapA_01780	ENOG4108R99	pseudouridine synthase
XapA_01795	ENOG4105CQ7	ATP-dependent helicase
XapA_01800	ENOG4108W15	Protein of unknown function (DUF1456)
XapA_01805	ENOG4105VT2	5-hydroxyisourate hydrolase
XapA_01810	ENOG4105E1J	oxidoreductase
XapA_01830	ENOG4105C5R	Aminotransferase
XapA_01840	ENOG4105EQ2	LysR family Transcriptional regulator
XapA_01845	ENOG4107RTG	Major Facilitator superfamily
XapA_01855	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
XapA_01865	ENOG4105DU0	nucleoside hydrolase
XapA_01875	ENOG4105C7N	Xanthine uracil vitamin C permease
XapA_01895	ENOG4105ETT	transcriptional Regulator, LysR family
XapA_01900	ENOG4105F8V	Hydrolase, tatD family
XapA_01920	ENOG4106NZI	LysR family Transcriptional regulator
XapA_01925	ENOG4105D94	Major Facilitator Superfamily
XapA_01940	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
XapA_01945	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
XapA_01965	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
XapA_01970	ENOG4105EB3	Histidine kinase
XapA_01975	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
XapA_01980	ENOG4105BZS	acriflavin resistance protein
XapA_01985	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
XapA_02000	ENOG4105WPN	DNA integration recombination invertion protein
XapA_02005	ENOG4105DZ2	Transcriptional regulator
XapA_02010	ENOG4108UZX	fmn reductase
XapA_02025	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
XapA_02040	ENOG4105ECR	NmrA family
XapA_02090	ENOG4105C01	Dihydroxy-acid dehydratase
XapA_02105	ENOG4108Z0R	Transferase
XapA_02115	ENOG4105D2S	major facilitator superfamily
XapA_02120	ENOG4105CPI	Metal Dependent Phosphohydrolase
XapA_02155	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
XapA_02165	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
XapA_02170	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
XapA_02175	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
XapA_02180	ENOG4105E98	transcriptional regulator DeoR family
XapA_02210	ENOG4105CHU	acetyl-coa acetyltransferase
XapA_02225	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
XapA_02230	ENOG4105F2Z	3-oxoadipate enol-lactonase
XapA_02235	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
XapA_02245	ENOG4107HP6	Transcriptional regulator
XapA_02260	ENOG4105MH3	Protein of unknown function (DUF2490)
XapA_02265	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
XapA_02300	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
XapA_02305	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
XapA_02315	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
XapA_02320	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
XapA_02325	ENOG41081UC	Inherit from COG: Competence protein
XapA_02330	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
XapA_02395	ENOG4105VS8	Flagellar biosynthetic protein fliq
XapA_02415	ENOG4108HR8	type iii secretion
XapA_02435	ENOG4107Y59	type iii secretion
XapA_02450	ENOG4108JIR	Flagellum-specific ATP synthase
XapA_02460	ENOG4108TN6	type iii secretion
XapA_02475	ENOG4105FTC	Lytic transglycosylase catalytic
XapA_02490	ENOG4105EGS	Mechanosensitive ion channel
XapA_02495	ENOG4107RES	phosphoglycerol transferase I
XapA_02510	ENOG4105CKW	Inner membrane protein yedI
XapA_02520	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
XapA_02525	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
XapA_02530	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
XapA_02555	ENOG4105K4T	epimerase
XapA_02560	ENOG4107ZQV	short-chain dehydrogenase reductase
XapA_02595	ENOG4105BZS	acriflavin resistance protein
XapA_02600	ENOG4105CHR	reductase
XapA_02615	ENOG4105C1J	atp-dependent rna helicase
XapA_02630	ENOG4105CPP	Dehydrogenase, E1 component
XapA_02635	ENOG4107RUY	(E1 component), alpha subunit
XapA_02650	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
XapA_02655	ENOG4105DUX	Transporter
XapA_02670	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
XapA_02680	ENOG4105F1J	Homogentisate 1,2-dioxygenase
XapA_02700	ENOG4105KJM	monovalent cation h antiporter subunit g
XapA_02705	ENOG4105W4C	monovalent cation H antiporter subunit F
XapA_02715	ENOG4107R4Z	monovalent cation h antiporter subunit d
XapA_02720	ENOG4108ZE9	Monovalent cation H antiporter subunit C
XapA_02725	ENOG4105D65	subunit l
XapA_02750	ENOG4105NVB	glycoside hydrolase, family 19
XapA_02770	ENOG4105C8V	SAICAR synthetase
XapA_02775	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
XapA_02790	ENOG4105KD7	acetyltransferase
XapA_02795	ENOG4107TE5	Lipid kinase
XapA_02800	ENOG4105CRQ	synthase (Component I)
XapA_02810	ENOG4105DDQ	anthranilate synthase
XapA_02820	ENOG4108I0Q	anthranilate phosphoribosyltransferase
XapA_02825	ENOG4105DK0	Indole-3-glycerol phosphate synthase
XapA_02835	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
XapA_02840	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
XapA_02850	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
XapA_02860	ENOG4108UJD	30S ribosomal protein S9
XapA_02875	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
XapA_02885	ENOG4108UQY	Iron-storage protein
XapA_02890	ENOG4105BZU	Histidine kinase
XapA_02915	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
XapA_02935	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
XapA_02955	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
XapA_02970	ENOG4105EM2	membrane
XapA_02980	ENOG4105C12	Phosphoribosylglycinamide synthetase
XapA_02990	ENOG4105DC1	bifunctional purine biosynthesis protein purh
XapA_02995	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
XapA_03000	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
XapA_03005	ENOG41077RS	Phosphatase
XapA_03030	ENOG4108HPI	phosphatidate Cytidylyltransferase
XapA_03035	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
XapA_03060	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
XapA_03080	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
XapA_03090	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
XapA_03095	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
XapA_03100	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
XapA_03105	ENOG4105VF7	tolerance protein
XapA_03120	ENOG4105VV6	START domain-containing protein
XapA_03135	ENOG4105E1F	short-chain dehydrogenase reductase
XapA_03145	ENOG4108K8S	endonuclease I
XapA_03155	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
XapA_03170	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
XapA_03195	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
XapA_03200	ENOG4105EX9	Membrane
XapA_03220	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
XapA_03225	ENOG4108YYC	ycei family
XapA_03255	ENOG4105WSE	Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity)
XapA_03270	ENOG41065ZS	Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme- A to the apo- acyl-carrier-protein of the malonate decarboxylase to yield holo- acyl-carrier-protein (By similarity)
XapA_03290	ENOG4105DRR	Transcriptional regulator, GntR family
XapA_03330	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
XapA_03365	ENOG4107GJV	short-chain dehydrogenase reductase
XapA_03380	ENOG4105PDP	Short chain dehydrogenase
XapA_03395	ENOG4105CHF	Glutathione S-transferase
XapA_03420	ENOG4105EYF	MMPL domain protein
XapA_03430	ENOG4105C5Z	peptidase
XapA_03440	ENOG4107QS8	(LipO)protein
XapA_03450	ENOG4105BZU	Histidine kinase
XapA_03475	ENOG4105DFI	Membrane
XapA_03480	ENOG4105F87	Dehydratase
XapA_03510	ENOG4105E53	ec 3.2.1.28
XapA_03570	ENOG4105C8Q	Methyl-accepting chemotaxis
XapA_03575	ENOG4106R7G	Glycoside hydrolase family 5
XapA_03580	ENOG4105CHH	sulfate transporter
XapA_03590	ENOG4105BZU	Histidine kinase
XapA_03610	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
XapA_03620	ENOG4108HRK	Histidine kinase
XapA_03625	ENOG4108NEV	two component transcriptional regulator, LytTR family
XapA_03630	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
XapA_03690	ENOG4105WD1	Membrane
XapA_03700	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
XapA_03710	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
XapA_03715	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
XapA_03720	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
XapA_03745	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
XapA_03750	ENOG41064RH	membrane protein YliF
XapA_03755	ENOG4105CD8	aminopeptidase N
XapA_03790	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
XapA_03805	ENOG4107QW3	Sucrose phosphorylase
XapA_03820	ENOG4105ETE	Transcriptional regulator (LacI family
XapA_03825	ENOG4105CHR	reductase
XapA_03830	ENOG4105D4T	Citrate transporter
XapA_03850	ENOG4105DHQ	Histidine kinase
XapA_03855	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
XapA_03865	ENOG4105WH1	Two component transcriptional regulator luxr family
XapA_03885	ENOG4105CPC	Aldo Keto reductase
XapA_03895	ENOG4105F04	LysR family Transcriptional regulator
XapA_03905	ENOG4105CSH	Transporter
XapA_03915	ENOG4105CQZ	Histidine kinase
XapA_03925	ENOG4105CK2	sodium dicarboxylate symporter
XapA_03930	ENOG4105C6K	Malic enzyme
XapA_03955	ENOG4105D1S	lipid A biosynthesis
XapA_03960	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
XapA_03965	ENOG4105DFG	type I secretion outer membrane protein
XapA_03970	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
XapA_03985	ENOG4108MP6	LysR family Transcriptional regulator
XapA_03990	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
XapA_03995	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
XapA_04000	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
XapA_04005	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
XapA_04010	ENOG4105C7B	Threonine dehydratase
XapA_04025	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
XapA_04035	ENOG4105C8Q	Methyl-accepting chemotaxis
XapA_04050	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
XapA_04055	ENOG4108M3R	transcriptional activator CadC
XapA_04060	ENOG4105ECQ	AraC Family Transcriptional Regulator
XapA_04085	ENOG4105F0N	pyrophosphate phospho-hydrolase
XapA_04095	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
XapA_04120	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
XapA_04125	ENOG4105DFU	Cell wall formation (By similarity)
XapA_04135	ENOG4105FFC	UPF0187 protein
XapA_04140	ENOG410841Q	phosphoesterase PA-phosphatase related protein
XapA_04160	ENOG4105EYW	Ion transport protein
XapA_04165	ENOG4105C8Y	Acetylornithine aminotransferase
XapA_04195	ENOG4105CIH	Imidazole acetol-phosphate transaminase
XapA_04205	ENOG41061ZR	Transcriptional regulator
XapA_04210	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
XapA_04225	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
XapA_04230	ENOG4105VCQ	rubredoxin
XapA_04235	ENOG41063JG	Transcriptional regulator
XapA_04245	ENOG4105E66	phosphoriboisomerase A
XapA_04255	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
XapA_04265	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
XapA_04280	ENOG4107RAQ	aminopeptidase
XapA_04290	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
XapA_04305	ENOG4105CSA	Coproporphyrinogen iii oxidase
XapA_04310	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
XapA_04320	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
XapA_04325	ENOG4105DSJ	YicC domain protein
XapA_04330	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
XapA_04340	ENOG4108EMV	Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity)
XapA_04345	ENOG4105CHR	reductase
XapA_04350	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
XapA_04365	ENOG4105TW1	Carbohydrate-selective porin OprB
XapA_04380	ENOG4105DKT	Transcriptional regulator
XapA_04385	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
XapA_04390	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
XapA_04395	ENOG4105KME	endoribonuclease L-psp
XapA_04400	ENOG4105CB5	ATP-dependent DNA helicase recG
XapA_04405	ENOG4105DU0	nucleoside hydrolase
XapA_04430	ENOG4108JQC	penicillin-binding protein 1A
XapA_04460	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
XapA_04480	ENOG4107QVM	von Willebrand factor, type A
XapA_04495	ENOG4105CK2	sodium dicarboxylate symporter
XapA_04500	ENOG4105CV1	Transketolase (EC 2.2.1.1)
XapA_04505	ENOG4107SKW	Inherit from COG: Alpha beta hydrolase
XapA_04510	ENOG4105CNM	Receptor
XapA_04520	ENOG4105DR5	peptidase
XapA_04530	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
XapA_04565	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
XapA_04570	ENOG4105E0C	molybdate abc transporter
XapA_04575	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
XapA_04580	ENOG4107S76	domain protein
XapA_04590	ENOG4105EIF	outer membrane protein W
XapA_04595	ENOG4105EIF	outer membrane protein W
XapA_04610	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
XapA_04635	ENOG4105BZA	Phosphoglycerate kinase
XapA_04645	ENOG4105CA9	Pyruvate kinase
XapA_04650	ENOG4107R1Y	fructose-bisphosphate aldolase
XapA_04655	ENOG4108UVJ	appr-1-p processing domain protein
XapA_04670	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
XapA_04675	ENOG4107R11	Transcriptional regulator
XapA_04690	ENOG4105BZU	Histidine kinase
XapA_04710	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
XapA_04715	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
XapA_04720	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
XapA_04725	ENOG4105C11	sulfate adenylyltransferase), subunit 2
XapA_04730	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
XapA_04735	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
XapA_04740	ENOG4105BZS	acriflavin resistance protein
XapA_04790	ENOG4105EIB	trna rrna methyltransferase
XapA_04820	ENOG4105ETE	Transcriptional regulator (LacI family
XapA_04830	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
XapA_04860	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
XapA_04870	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
XapA_04915	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
XapA_04925	ENOG4105ETX	regulatoR
XapA_04930	ENOG4105BZU	Histidine kinase
XapA_05040	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
XapA_05060	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
XapA_05065	ENOG4107T4Z	adenosine kinase
XapA_05075	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
XapA_05090	ENOG4105CNI	cell division protein FtsW
XapA_05100	ENOG4105CVE	Lytic murein transglycosylase
XapA_05105	ENOG4105K6T	rare lipoprotein A
XapA_05115	ENOG4105DZ1	carboxypeptidase
XapA_05130	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
XapA_05135	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
XapA_05140	ENOG4105CN1	protease
XapA_05150	ENOG4105EGI	Transcriptional regulator
XapA_05195	ENOG4108J5G	6-phosphogluconate dehydrogenase
XapA_05200	ENOG4105D9R	oxidoreductase
XapA_05205	ENOG4105W4M	Transport-associated protein
XapA_05210	ENOG4105BZU	Histidine kinase
XapA_05220	ENOG4105BZU	Histidine kinase
XapA_05230	ENOG4105CHR	reductase
XapA_05275	ENOG4105GVR	general secretion pathway protein D
XapA_05280	ENOG4107QHF	type ii secretion system protein e
XapA_05285	ENOG4105D7Q	type ii secretion system
XapA_05290	ENOG4108VAU	general secretion pathway protein G
XapA_05295	ENOG4105VWV	general secretion pathway protein h
XapA_05300	ENOG4105X5Z	General secretion pathway protein I
XapA_05310	ENOG4108RTD	type II secretion system protein K
XapA_05335	ENOG4105CNT	hydrolase family 2
XapA_05360	ENOG4105ETE	Transcriptional regulator (LacI family
XapA_05365	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
XapA_05370	ENOG4105CE4	GlcNAc 6-P deacetylase
XapA_05380	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
XapA_05385	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
XapA_05390	ENOG4105C26	Dehydrogenase
XapA_05395	ENOG4105C94	Transporter
XapA_05410	ENOG4108Z33	Thiol disulfide Interchange Protein
XapA_05420	ENOG4106RE7	Cytochrome
XapA_05425	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
XapA_05430	ENOG4105CY0	Metallo-Beta-Lactamase
XapA_05450	ENOG4105JJR	Histidine kinase
XapA_05480	ENOG4108QBQ	Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione (By similarity)
XapA_05495	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
XapA_05500	ENOG4105JAB	phenazine biosynthesis protein, phzf family
XapA_05515	ENOG4105C5H	ABC transporter
XapA_05525	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
XapA_05530	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
XapA_05540	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
XapA_05555	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
XapA_05560	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
XapA_05565	ENOG4107YIM	Involved in the transcription termination process (By similarity)
XapA_05570	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
XapA_05595	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
XapA_05600	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
XapA_05605	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
XapA_05610	ENOG4105C08	Histidine kinase
XapA_05615	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
XapA_05645	ENOG4105CQB	FAD linked oxidase domain protein
XapA_05650	ENOG4105S2T	inner membrane protein YbcI
XapA_05655	ENOG41082RQ	UPF0102 protein
XapA_05695	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
XapA_05700	ENOG4106932	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
XapA_05705	ENOG4105CJN	penicillin-binding protein
XapA_05710	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
XapA_05715	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
XapA_05720	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
XapA_05730	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
XapA_05735	ENOG4105DFU	Cell wall formation (By similarity)
XapA_05740	ENOG4105CPF	Cell wall formation (By similarity)
XapA_05745	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
XapA_05750	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
XapA_05755	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
XapA_05760	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
XapA_05775	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
XapA_05780	ENOG4105M6F	mutator MutT protein
XapA_05790	ENOG4105SYT	Methylenetetrahydrofolate reductase
XapA_05870	ENOG4105DXX	methyltransferase
XapA_05875	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
XapA_05885	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
XapA_05930	ENOG4105D6F	Phosphatase
XapA_05945	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
XapA_05950	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
XapA_05960	ENOG4108RVA	ribokinase
XapA_05965	ENOG4105D9N	nucleoside
XapA_05975	ENOG4105CPC	Aldo Keto reductase
XapA_05985	ENOG4105D05	Receptor
XapA_06005	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
XapA_06020	ENOG4105E2B	Taurine dioxygenase
XapA_06030	ENOG4108I0Y	(ABC) transporter
XapA_06035	ENOG4108UJV	acyl-CoA thioesterase i
XapA_06045	ENOG4105DHQ	Histidine kinase
XapA_06065	ENOG41080IJ	Diacylglycerol kinase
XapA_06080	ENOG4107RZC	phospholipase d
XapA_06085	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
XapA_06090	ENOG4105BZU	Histidine kinase
XapA_06095	ENOG4105BZU	Histidine kinase
XapA_06100	ENOG4108V3W	Chemotaxis protein, CheW
XapA_06105	ENOG4105C8Q	Methyl-accepting chemotaxis
XapA_06110	ENOG4105CBS	Chea signal transduction histidine kinase
XapA_06120	ENOG4108JA2	transcriptioN-repair coupling factor
XapA_06130	ENOG4105D6S	protein involved in catabolism of external DNA
XapA_06140	ENOG4105EB3	Histidine kinase
XapA_06145	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
XapA_06155	ENOG4105CT7	inner membrane cred family protein
XapA_06180	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
XapA_06185	ENOG4105MYN	Zinc uptake regulation protein
XapA_06195	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
XapA_06200	ENOG4105BZS	acriflavin resistance protein
XapA_06205	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
XapA_06220	ENOG4105CF7	AraC family transcriptional regulator
XapA_06230	ENOG4105CC0	LysR family Transcriptional regulator
XapA_06235	ENOG4105F27	Major Facilitator
XapA_06280	ENOG4105UGU	tonB-dependent Receptor
XapA_06305	ENOG4105CMQ	Chloride channel
XapA_06320	ENOG4105D03	DNA-3-methyladenine glycosylase II
XapA_06370	ENOG4105BZU	Histidine kinase
XapA_06375	ENOG4105FE9	pseudouridine synthase
XapA_06400	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
XapA_06405	ENOG4105FQP	Beta-lactamase
XapA_06415	ENOG4105BZU	Histidine kinase
XapA_06420	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
XapA_06425	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
XapA_06455	ENOG4105BZ1	(ABC) transporter
XapA_06500	ENOG4105WG9	Conserved Protein
XapA_06540	ENOG4107QR8	Thioredoxin
XapA_06550	ENOG4105C8T	Leucyl-tRNA synthetase
XapA_06565	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
XapA_06580	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
XapA_06600	ENOG4105MPN	Membrane
XapA_06605	ENOG4108Z03	MAF-like protein
XapA_06610	ENOG4105C03	ribonuclease
XapA_06615	ENOG4105QD6	exported protein
XapA_06625	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
XapA_06630	ENOG4105N42	UPF0307 protein
XapA_06635	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
XapA_06650	ENOG4106RHG	Yeca family
XapA_06670	ENOG4108C33	Resolvase
XapA_06680	ENOG4105CTB	Polyprenyl synthetase
XapA_06685	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
XapA_06690	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
XapA_06700	ENOG4105G6Z	alkaline phosphatase
XapA_06710	ENOG41082K6	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
XapA_06720	ENOG4105K4H	Nlp p60 protein
XapA_06725	ENOG4105K4H	Nlp p60 protein
XapA_06730	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
XapA_06740	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
XapA_06745	ENOG4105DC8	reductase
XapA_06770	ENOG4105C9K	Endothelin-converting enzyme 1
XapA_06780	ENOG4105C9K	Endothelin-converting enzyme 1
XapA_06840	ENOG4105CNA	YD repeat protein
XapA_06870	ENOG4105CMM	transposase
XapA_06890	ENOG4105CNT	hydrolase family 2
XapA_06895	ENOG4106FKC	arabinogalactan endo-1,4-beta-galactosidase
XapA_06910	ENOG4105C26	Dehydrogenase
XapA_06915	ENOG4105C1G	acyl-Coa dehydrogenase
XapA_06920	ENOG4105E39	Enoyl-CoA hydratase
XapA_06925	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
XapA_06945	ENOG4105EMN	RNA polymerase sigma factor
XapA_06955	ENOG4105C0H	protease
XapA_06960	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
XapA_06965	ENOG4105C3F	Signal peptidase i
XapA_06975	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
XapA_06980	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
XapA_06995	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
XapA_07010	ENOG4107ZXU	DSBA oxidoreductase
XapA_07015	ENOG4108QDE	fad dependent oxidoreductase
XapA_07020	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
XapA_07025	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
XapA_07030	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
XapA_07035	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
XapA_07045	ENOG4105VEQ	Cold shock protein
XapA_07060	ENOG4107QRT	dEAD DEAH box helicase
XapA_07065	ENOG4107T0X	DNA ligase
XapA_07075	ENOG4107T0X	DNA ligase
XapA_07105	ENOG4105CHU	acetyl-coa acetyltransferase
XapA_07130	ENOG4108VKG	metal-dependent hydrolase
XapA_07145	ENOG4105KSC	Transcriptional regulator, TraR DksA family
XapA_07165	ENOG4108YZY	peptidylprolyl cis-trans isomerase
XapA_07175	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
XapA_07190	ENOG4105F27	Major Facilitator
XapA_07230	ENOG4105M4H	endoribonuclease L-psp
XapA_07235	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
XapA_07250	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
XapA_07275	ENOG4105K6V	RNA polymerase
XapA_07295	ENOG4108R3D	Electron transport complex
XapA_07305	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
XapA_07320	ENOG4105DA5	(ABC) transporter
XapA_07325	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
XapA_07330	ENOG4108IQI	permease
XapA_07335	ENOG4107QK5	Homocysteine s-methyltransferase
XapA_07385	ENOG4108YXA	Membrane
XapA_07400	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
XapA_07410	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
XapA_07415	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
XapA_07420	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
XapA_07425	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
XapA_07430	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
XapA_07445	ENOG4105DZP	Membrane-associated zinc metalloprotease
XapA_07450	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
XapA_07455	ENOG4105KNE	Phosphatidate cytidylyltransferase
XapA_07460	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
XapA_07465	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
XapA_07470	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
XapA_07480	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
XapA_07485	ENOG4105CE9	30S ribosomal protein S2
XapA_07520	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
XapA_07525	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
XapA_07535	ENOG4105KUZ	arsenate reductase
XapA_07540	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
XapA_07545	ENOG4105CAQ	asparagine synthetase
XapA_07555	ENOG4108ESX	Receptor
XapA_07565	ENOG4108UWD	Iron-storage protein
XapA_07580	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
XapA_07600	ENOG4105CW7	secretion protein, HlyD family
XapA_07605	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
XapA_07630	ENOG4105DUX	Transporter
XapA_07660	ENOG4105DGW	oligopeptidase A
XapA_07670	ENOG4108V06	Glutathione peroxidase
XapA_07675	ENOG4105DP0	ferredoxin-NADP reductase
XapA_07685	ENOG4107GFK	fumarate
XapA_07705	ENOG4105HDD	phospholipase
XapA_07715	ENOG4105VEQ	Cold shock protein
XapA_07730	ENOG4105CUZ	uba thif-type nad fad binding protein
XapA_07735	ENOG4105F8V	Hydrolase, tatD family
XapA_07750	ENOG4105C1G	acyl-Coa dehydrogenase
XapA_07760	ENOG4108K3A	Glutathione S-transferase
XapA_07770	ENOG4105CAQ	asparagine synthetase
XapA_07780	ENOG4105CDU	Replicative dna helicase
XapA_07785	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
XapA_07795	ENOG4105CDV	Ompa motb domain protein
XapA_07805	ENOG4105CR8	Transcriptional regulator
XapA_07845	ENOG4105BZU	Histidine kinase
XapA_07855	ENOG4106TD9	Diguanylate cyclase
XapA_07885	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
XapA_07890	ENOG4108Z1B	Cyclase dehydrase
XapA_07900	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
XapA_07905	ENOG41090R7	Ferric uptake
XapA_07910	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
XapA_07915	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
XapA_07920	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XapA_07925	ENOG4105CFG	Acts as a chaperone (By similarity)
XapA_07930	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
XapA_07970	ENOG4105C5Q	Transcriptional regulator
XapA_07975	ENOG4105BZ1	(ABC) transporter
XapA_07985	ENOG4108URH	decarboxylase
XapA_07995	ENOG4105C7S	Dehydrogenase
XapA_08000	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
XapA_08010	ENOG4105EZE	Cupin 4 family protein
XapA_08020	ENOG4107QTF	adenylosuccinate lyase
XapA_08030	ENOG4105C37	(CBS) domain
XapA_08060	ENOG4105CZV	ABC transporter
XapA_08065	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
XapA_08080	ENOG4108V1T	peptidylprolyl cis-trans isomerase
XapA_08085	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
XapA_08090	ENOG41069P5	Protein slyX homolog
XapA_08105	ENOG4105ETE	Transcriptional regulator (LacI family
XapA_08115	ENOG4105D7K	pfkb domain protein
XapA_08140	ENOG4105C3R	Methionine synthase
XapA_08145	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
XapA_08150	ENOG4105C1G	acyl-Coa dehydrogenase
XapA_08155	ENOG4105C1G	acyl-Coa dehydrogenase
XapA_08175	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
XapA_08185	ENOG4105C2N	RNA methyltransferase TrmH family group 3
XapA_08190	ENOG4105BZU	Histidine kinase
XapA_08195	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
XapA_08205	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
XapA_08210	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
XapA_08215	ENOG4105E2Z	phosphate ABC transporter (Permease
XapA_08220	ENOG4105C8U	phosphate abc transporter
XapA_08225	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
XapA_08250	ENOG4105CHH	sulfate transporter
XapA_08255	ENOG4105CSM	endonuclease III
XapA_08265	ENOG4105E39	Enoyl-CoA hydratase
XapA_08270	ENOG4108V1T	peptidylprolyl cis-trans isomerase
XapA_08275	ENOG4105P8F	nudix hydrolase
XapA_08280	ENOG4105KHC	sulfurtransferase
XapA_08325	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
XapA_08350	ENOG4105CJB	Exodeoxyribonuclease I
XapA_08360	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
XapA_08365	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
XapA_08375	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
XapA_08380	ENOG41077A9	carbonic anhydrase
XapA_08425	ENOG4105WH1	Two component transcriptional regulator luxr family
XapA_08465	ENOG4105C5S	asparaginyl-tRNA synthetase
XapA_08475	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
XapA_08480	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
XapA_08485	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
XapA_08490	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
XapA_08500	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
XapA_08510	ENOG4105CIH	Imidazole acetol-phosphate transaminase
XapA_08515	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
XapA_08520	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
XapA_08535	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
XapA_08540	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
XapA_08545	ENOG4105DZG	Dehydrogenase
XapA_08555	ENOG4105CGP	Urocanate hydratase
XapA_08565	ENOG4105C84	Histidine ammonia-lyase
XapA_08570	ENOG4105CI2	imidazolone-5-propionate hydrolase
XapA_08610	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
XapA_08615	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
XapA_08620	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
XapA_08630	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
XapA_08645	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
XapA_08650	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
XapA_08655	ENOG4105CC0	LysR family Transcriptional regulator
XapA_08680	ENOG4105C8Q	Methyl-accepting chemotaxis
XapA_08705	ENOG4105BZU	Histidine kinase
XapA_08730	ENOG4105KWW	Biogenesis protein
XapA_08735	ENOG4107QX9	Thiol disulfide interChange protein
XapA_08740	ENOG4105DA4	cytochrome c-type biogenesis protein
XapA_08745	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
XapA_08755	ENOG41060IM	Heme exporter protein
XapA_08770	ENOG4105EMN	RNA polymerase sigma factor
XapA_08825	ENOG4105EGZ	biosynthesis protein
XapA_08860	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
XapA_08885	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
XapA_08890	ENOG4105BZ1	(ABC) transporter
XapA_08895	ENOG41079KZ	Major Facilitator Superfamily
XapA_08900	ENOG4105DEN	Luciferase family
XapA_08930	ENOG4105CJ3	phosphate transporter
XapA_08945	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
XapA_08955	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
XapA_08960	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
XapA_08970	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
XapA_08975	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
XapA_08980	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
XapA_08985	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
XapA_08990	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
XapA_08995	ENOG4108DG9	Smr protein MutS2
XapA_09000	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
XapA_09005	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
XapA_09010	ENOG4108UM1	dedA family
XapA_09015	ENOG4108K5P	(LipO)protein
XapA_09025	ENOG4105HBR	Rna-binding protein
XapA_09030	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
XapA_09035	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
XapA_09040	ENOG4105EEI	dihydropteroate synthase
XapA_09045	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
XapA_09055	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
XapA_09060	ENOG4107TH8	cina domain protein
XapA_09070	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
XapA_09075	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
XapA_09085	ENOG4105Y3E	Modulates RecA activity (By similarity)
XapA_09090	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
XapA_09110	ENOG4107SDU	Methyl-accepting chemotaxis
XapA_09120	ENOG4105CWB	LysR family transcriptional Regulator
XapA_09160	ENOG4108IAB	Phoh family
XapA_09165	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XapA_09180	ENOG4107TUS	Dihydrodipicolinate synthase
XapA_09190	ENOG4108Z4U	Ferredoxin
XapA_09195	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
XapA_09205	ENOG4105CXK	mandelate racemase muconate lactonizing
XapA_09210	ENOG4108RTU	Aldolase
XapA_09260	ENOG4105CMG	Carbohydrate kinase
XapA_09265	ENOG4105C93	Xylose Isomerase
XapA_09290	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
XapA_09295	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
XapA_09305	ENOG4105DJ0	Poly(A) Polymerase
XapA_09310	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XapA_09315	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
XapA_09320	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
XapA_09325	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
XapA_09330	ENOG4107QP8	phosphohexose isomerase
XapA_09380	ENOG4105KU2	hydrolase family 5
XapA_09385	ENOG4108UYB	regulatoR
XapA_09400	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
XapA_09405	ENOG410841Q	phosphoesterase PA-phosphatase related protein
XapA_09435	ENOG4105D4A	Cell wall formation (By similarity)
XapA_09440	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
XapA_09460	ENOG4105C26	Dehydrogenase
XapA_09485	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
XapA_09490	ENOG4106H78	methyltransferase
XapA_09495	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
XapA_09510	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
XapA_09515	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
XapA_09520	ENOG4105E08	Glycoside hydrolase, family 9
XapA_09525	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
XapA_09565	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
XapA_09570	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
XapA_09575	ENOG4105VIE	preprotein translocase, subunit YajC
XapA_09580	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
XapA_09585	ENOG4107QT7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
XapA_09625	ENOG4105DM4	PTS System
XapA_09630	ENOG4105DE4	1-phosphofructokinase
XapA_09635	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
XapA_09640	ENOG4108M60	Transcriptional regulator
XapA_09650	ENOG4105BZS	acriflavin resistance protein
XapA_09655	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
XapA_09665	ENOG4105C7I	Dehydrogenase
XapA_09700	ENOG4105W39	Membrane
XapA_09715	ENOG4108RCM	Nitroreductase
XapA_09720	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
XapA_09755	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
XapA_09850	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
XapA_09855	ENOG41090A4	Pterin carbinolamine dehydratase
XapA_09865	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
XapA_09870	ENOG4108NST	exported protein
XapA_09875	ENOG4105EI2	Pseudouridine synthase
XapA_09880	ENOG4105C03	ribonuclease
XapA_09890	ENOG4105C72	UPF0176 protein
XapA_09900	ENOG4108V1T	peptidylprolyl cis-trans isomerase
XapA_09910	ENOG4107QQG	Dehydrogenase
XapA_09935	ENOG4105CEY	Amp-dependent synthetase and ligase
XapA_10015	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
XapA_10020	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
XapA_10035	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
XapA_10040	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
XapA_10045	ENOG4105BZ1	(ABC) transporter
XapA_10060	ENOG4108EC8	DNA internalization-related competence protein ComEC
XapA_10070	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
XapA_10075	ENOG4105D60	lipoprotein releasing system transmembrane protein
XapA_10085	ENOG410681N	tpr repeat protein
XapA_10090	ENOG4105E33	succinate dehydrogenase
XapA_10110	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
XapA_10135	ENOG4105CHC	glucokinase (EC 2.7.1.2)
XapA_10140	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
XapA_10145	ENOG4105C01	Dihydroxy-acid dehydratase
XapA_10150	ENOG4108UHU	Aldolase
XapA_10180	ENOG4105N7H	Cytochrome
XapA_10225	ENOG4105BZU	Histidine kinase
XapA_10230	ENOG4105BZM	domain protein
XapA_10255	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
XapA_10265	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
XapA_10285	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
XapA_10315	ENOG4105XMH	SpoVT AbrB domain protein
XapA_10380	ENOG4106RHG	Yeca family
XapA_10400	ENOG4108C33	Resolvase
XapA_10430	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
XapA_10435	ENOG4108Z6B	deaminase
XapA_10440	ENOG4105KST	dependent repressor
XapA_10445	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
XapA_10465	ENOG4107SFI	Major Facilitator superfamily
XapA_10490	ENOG4105CHJ	isochorismatase hydrolase
XapA_10505	ENOG4105WH1	Two component transcriptional regulator luxr family
XapA_10525	ENOG4105DND	Transcriptional regulator
XapA_10535	ENOG4105EVH	UPF0753 protein
XapA_10540	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
XapA_10545	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
XapA_10550	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
XapA_10560	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
XapA_10570	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
XapA_10580	ENOG4105ESV	Glycosyl transferase, family 4
XapA_10585	ENOG4105CFV	Tetratricopeptide repeat protein
XapA_10595	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
XapA_10600	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
XapA_10605	ENOG4105CAT	Cytidine monophosphate kinase
XapA_10625	ENOG4105DWY	Agmatine deiminase
XapA_10655	ENOG4105DRS	transport system, permease
XapA_10660	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
XapA_10690	ENOG4105K9H	YciI-like protein
XapA_10695	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
XapA_10700	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
XapA_10705	ENOG4105FE9	pseudouridine synthase
XapA_10725	ENOG4105CHM	Aminotransferase
XapA_10730	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
XapA_10735	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
XapA_10740	ENOG41060IM	Heme exporter protein
XapA_10750	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
XapA_10755	ENOG4105DA4	cytochrome c-type biogenesis protein
XapA_10765	ENOG4105KWW	Biogenesis protein
XapA_10785	ENOG4108JJ8	(ABC) transporter
XapA_10790	ENOG4108JJ9	ABC, transporter
XapA_10795	ENOG4105C4M	(Ubiquinol oxidase) subunit I
XapA_10800	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
XapA_10810	ENOG4105EKQ	RNA-directed DNA polymerase
XapA_10835	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
XapA_10840	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
XapA_10850	ENOG4105CH7	arginosuccinase
XapA_10855	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
XapA_10865	ENOG4105CAS	nag kinase
XapA_10880	ENOG4105CDH	Citrulline--aspartate ligase
XapA_10885	ENOG4105DBV	ornithine carbamoyltransferase
XapA_10895	ENOG4105C8N	cysteinyl-tRNA synthetase
XapA_10900	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
XapA_10915	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
XapA_10920	ENOG4105CD3	dihydroorotase
XapA_10945	ENOG4105CPD	ethanolamine ammonia-lyase
XapA_10950	ENOG4107FQ9	ethanolamine ammonia-lyase
XapA_11015	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
XapA_11020	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
XapA_11025	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
XapA_11035	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
XapA_11040	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
XapA_11045	ENOG4105BZU	Histidine kinase
XapA_11060	ENOG4105ECY	inositol monophosphatase
XapA_11065	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
XapA_11085	ENOG4105C5H	ABC transporter
XapA_11090	ENOG4105C1J	atp-dependent rna helicase
XapA_11095	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
XapA_11100	ENOG4105CNG	UPF0061 protein
XapA_11110	ENOG4108RXX	maleylacetoacetate isomerase
XapA_11115	ENOG4105VEQ	Cold shock protein
XapA_11120	ENOG4108VWS	Yaeq family
XapA_11125	ENOG4105CBX	hi0933 family
XapA_11160	ENOG4108C33	Resolvase
XapA_11170	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
XapA_11175	ENOG4105CHR	reductase
XapA_11200	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
XapA_11205	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
XapA_11210	ENOG4105K8N	protein family UPF0079, ATPase
XapA_11215	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
XapA_11220	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
XapA_11225	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
XapA_11240	ENOG4105E6M	Sulphatase-modifying factor protein
XapA_11280	ENOG4108V3W	Chemotaxis protein, CheW
XapA_11285	ENOG4105C8Q	Methyl-accepting chemotaxis
XapA_11290	ENOG4108VX5	3-methyladenine DNA glycosylase
XapA_11295	ENOG4107QRT	dEAD DEAH box helicase
XapA_11315	ENOG4105KB2	stringent starvation protein b
XapA_11320	ENOG4107MKT	Stringent starvation protein a
XapA_11325	ENOG4105EIX	cytochrome c1
XapA_11330	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
XapA_11345	ENOG4105E4C	Lytic transglycosylase catalytic
XapA_11360	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
XapA_11365	ENOG4105C9A	Phoh family
XapA_11375	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
XapA_11385	ENOG4108JU5	Magnesium and cobalt efflux protein
XapA_11405	ENOG4105D38	putrescine abc transporter
XapA_11410	ENOG4105F38	ABC transporter, permease
XapA_11415	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
XapA_11435	ENOG4107RUE	extracellular solute-binding protein family 1
XapA_11440	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
XapA_11455	ENOG4105CFQ	glutamine synthetase
XapA_11460	ENOG4105CJP	fad dependent oxidoreductase
XapA_11470	ENOG4105W3S	hemerythrin-like, metal-binding protein
XapA_11485	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
XapA_11490	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
XapA_11515	ENOG4106BRA	Membrane
XapA_11520	ENOG4105BZU	Histidine kinase
XapA_11525	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
XapA_11530	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
XapA_11560	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
XapA_11580	ENOG4108ZXC	Two component transcriptional regulator, luxr family
XapA_11610	ENOG4108N8X	transition metal ion binding
XapA_11650	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
XapA_11660	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
XapA_11675	ENOG4105CGK	Exodeoxyribonuclease III
XapA_11715	ENOG4105D06	uba thif-type nad fad binding protein
XapA_11725	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
XapA_11730	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
XapA_11735	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
XapA_11745	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
XapA_11755	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
XapA_11775	ENOG4105CHU	acetyl-coa acetyltransferase
XapA_11785	ENOG41082MI	Protein CrcB homolog
XapA_11790	ENOG4105D1H	recombination factor protein RarA
XapA_11800	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
XapA_11810	ENOG4105CNU	cell division protein FtsK
XapA_11815	ENOG4105C3M	thioredoxin reductase
XapA_11825	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
XapA_11835	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
XapA_11850	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
XapA_11880	ENOG4105BZU	Histidine kinase
XapA_11885	ENOG4105BZU	Histidine kinase
XapA_11915	ENOG4108ZC9	flagellar basal-body rod protein flgc
XapA_11920	ENOG410822I	Flagellar hook capping protein
XapA_11925	ENOG4105BZE	flagellar hook protein, FlgE
XapA_11935	ENOG4108KPB	Flagellar basal-body rod protein FlgF
XapA_11945	ENOG4105CGA	flagellar basal-body rod protein FlgG
XapA_11950	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
XapA_11955	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
XapA_11960	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
XapA_11970	ENOG4105DTJ	flagellar hook-associated protein
XapA_11980	ENOG4107W9T	flagellar hook-associated
XapA_11985	ENOG4105MQ3	flagellar protein FliS
XapA_12005	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
XapA_12010	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
XapA_12055	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
XapA_12060	ENOG4105CHR	reductase
XapA_12100	ENOG4107RGC	Glycosyl transferase, family 2
XapA_12105	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
XapA_12110	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
XapA_12115	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
XapA_12125	ENOG4108JIR	Flagellum-specific ATP synthase
XapA_12145	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
XapA_12150	ENOG4105DD5	Flagellar motor switch protein
XapA_12155	ENOG4105K0P	flagellar biosynthesis protein
XapA_12160	ENOG4105CN7	Flagellar biosynthetic protein FliP
XapA_12170	ENOG4105VS8	Flagellar biosynthetic protein fliq
XapA_12175	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
XapA_12180	ENOG4105BZU	Histidine kinase
XapA_12200	ENOG4105D00	flagellar biosynthetic protein flhB
XapA_12205	ENOG4105D7B	Flagellar biosynthesis protein flha
XapA_12210	ENOG4105FZW	flagellar biosynthesis regulator FlhF
XapA_12220	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
XapA_12225	ENOG4108VYJ	response regulator receiver protein
XapA_12250	ENOG4105C4X	radical SAM domain protein
XapA_12285	ENOG4105E14	MotA TolQ exbB proton channel
XapA_12290	ENOG4105ER2	Ompa motb domain protein
XapA_12300	ENOG4108V3W	Chemotaxis protein, CheW
XapA_12310	ENOG4108VYJ	response regulator receiver protein
XapA_12315	ENOG4105CBS	Chea signal transduction histidine kinase
XapA_12320	ENOG4105C8Q	Methyl-accepting chemotaxis
XapA_12335	ENOG4105C8Q	Methyl-accepting chemotaxis
XapA_12350	ENOG4105C8Q	Methyl-accepting chemotaxis
XapA_12355	ENOG4105C8Q	Methyl-accepting chemotaxis
XapA_12365	ENOG4105C8Q	Methyl-accepting chemotaxis
XapA_12370	ENOG4105C8Q	Methyl-accepting chemotaxis
XapA_12380	ENOG4105C8Q	Methyl-accepting chemotaxis
XapA_12385	ENOG4105C8Q	Methyl-accepting chemotaxis
XapA_12390	ENOG4105C8Q	Methyl-accepting chemotaxis
XapA_12395	ENOG4105C8Q	Methyl-accepting chemotaxis
XapA_12400	ENOG4105C8Q	Methyl-accepting chemotaxis
XapA_12410	ENOG4108V3W	Chemotaxis protein, CheW
XapA_12420	ENOG4105C8Q	Methyl-accepting chemotaxis
XapA_12425	ENOG4105BZU	Histidine kinase
XapA_12430	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
XapA_12435	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
XapA_12440	ENOG4105BZU	Histidine kinase
XapA_12445	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
XapA_12450	ENOG4107QIJ	Aconitate hydratase 2
XapA_12465	ENOG4107QM5	aconitate hydratase
XapA_12475	ENOG4105CEY	Amp-dependent synthetase and ligase
XapA_12510	ENOG4105E39	Enoyl-CoA hydratase
XapA_12515	ENOG4105BZU	Histidine kinase
XapA_12520	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
XapA_12525	ENOG4105CRK	lysyL-tRNA synthetase
XapA_12535	ENOG4105DY9	regulatoR
XapA_12585	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
XapA_12595	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
XapA_12600	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
XapA_12610	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
XapA_12615	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
XapA_12620	ENOG4108RPX	mosc domain containing protein
XapA_12640	ENOG4105CE1	Ferrous iron transport protein b
XapA_12660	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
XapA_12670	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
XapA_12690	ENOG4105CQB	FAD linked oxidase domain protein
XapA_12695	ENOG4108JQ1	Dehydrogenase
XapA_12705	ENOG4105CUB	amino acid
XapA_12715	ENOG4106S9K	Transcriptional regulator
XapA_12770	ENOG4105CUB	amino acid
XapA_12775	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
XapA_12780	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
XapA_12785	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
XapA_12800	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
XapA_12805	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
XapA_12810	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
XapA_12815	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
XapA_12820	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
XapA_12825	ENOG4105CIH	Imidazole acetol-phosphate transaminase
XapA_12830	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
XapA_12835	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
XapA_12845	ENOG4105CUT	histidyl-tRNA synthetase
XapA_12850	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
XapA_12945	ENOG4107BJW	polysaccharide deacetylase
XapA_13090	ENOG4107QTZ	amino acid
XapA_13105	ENOG4105DC7	peptidase M24
XapA_13115	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
XapA_13130	ENOG41080HI	glycine oxidase
XapA_13135	ENOG4105CTU	Proline racemase
XapA_13145	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
XapA_13155	ENOG4105CEN	a g-specific adenine glycosylase
XapA_13160	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
XapA_13165	ENOG4105CQZ	Histidine kinase
XapA_13210	ENOG4105QNF	Outer membrane lipoprotein
XapA_13225	ENOG4105CSU	acyl-Coa dehydrogenase
XapA_13235	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
XapA_13255	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
XapA_13260	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
XapA_13265	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
XapA_13290	ENOG4108NQK	Catalyzes the transfer of a glucuronic acid (GlcA) residue from UDP-glucuronate to mannose-alpha-1,3-glucose-beta- 1,4-glucose-P-P-polyisoprenyl to form the lipid-linked tetrasaccharide GlcA-Man-Glc(2)-PP-Pol, with a glucuronic acid- beta-mannose linkage. Is involved in the biosynthesis of the exopolysaccharide xanthan, since it catalyzes the fourth glycosylation step in the assembly of the pentasaccharide-P-P- polyisoprenyl repeating unit of xanthan. Is unable to use the trisaccharide acceptor freed from the pyrophosphate lipid moiety. Does not show specificity for the lipidic portion of the acceptor. Shows diminished activity when tested with 6-O-acetyl-mannose- alpha-1,3-glucose-beta-1,4-glucose-P-P-polyisoprenyl, a
XapA_13300	ENOG4107Y2G	Glycosyl transferase (Group 1
XapA_13325	ENOG4105D3Q	Sugar transferase
XapA_13345	ENOG4105WJX	transcriptional regulator MERR family
XapA_13355	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
XapA_13360	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
XapA_13375	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
XapA_13380	ENOG4105C22	threonyL-tRNA synthetase
XapA_13385	ENOG4105ETE	Transcriptional regulator (LacI family
XapA_13430	ENOG4105CMA	conjugation trbi family protein
XapA_13470	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
XapA_13525	ENOG4105EWT	decarboxylase family
XapA_13530	ENOG4108KPZ	tonB-dependent Receptor
XapA_13540	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
XapA_13550	ENOG4105M2J	Glutaredoxin
XapA_13555	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
XapA_13560	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
XapA_13565	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
XapA_13575	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
XapA_13585	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
XapA_13595	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
XapA_13600	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
XapA_13605	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
XapA_13610	ENOG4105CHV	Transcription elongation factor NusA
XapA_13615	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
XapA_13625	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
XapA_13630	ENOG4105C8S	subunit m
XapA_13635	ENOG4105D65	subunit l
XapA_13650	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
XapA_13655	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
XapA_13660	ENOG4107R0R	NADH dehydrogenase subunit g
XapA_13665	ENOG4107QIZ	NADH dehydrogenase
XapA_13670	ENOG4105GKE	subunit e
XapA_13675	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
XapA_13680	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XapA_13685	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
XapA_13690	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XapA_13705	ENOG4105CP7	Triose-phosphate isomerase
XapA_13710	ENOG4107FW0	short-chain dehydrogenase reductase
XapA_13725	ENOG4105BZU	Histidine kinase
XapA_13740	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
XapA_13745	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
XapA_13750	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
XapA_13760	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
XapA_13770	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
XapA_13775	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
XapA_13795	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
XapA_13800	ENOG4105C5I	Dehydrogenase
XapA_13805	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
XapA_13810	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
XapA_13820	ENOG4105DJ4	phosphatidylserine decarboxylase
XapA_13835	ENOG4105D7A	ATP-binding protein
XapA_13840	ENOG4107VIJ	nudix hydrolase
XapA_13860	ENOG4108RRZ	Transcription elongation factor GreB
XapA_13865	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
XapA_13880	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
XapA_13910	ENOG4105ED4	portal protein
XapA_13955	ENOG4105NVB	glycoside hydrolase, family 19
XapA_14150	ENOG4105DHP	deoxycytidine triphosphate deaminase
XapA_14185	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
XapA_14195	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
XapA_14200	ENOG4105VEJ	Heat shock protein
XapA_14215	ENOG4107QJQ	Mate efflux family protein
XapA_14220	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
XapA_14225	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
XapA_14230	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
XapA_14235	ENOG4105K5M	30s ribosomal protein S16
XapA_14245	ENOG4107QWG	2-Nitropropane dioxygenase
XapA_14250	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XapA_14255	ENOG4105CRE	cytochrome C
XapA_14260	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
XapA_14265	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
XapA_14295	ENOG4105BZU	Histidine kinase
XapA_14300	ENOG4105BZU	Histidine kinase
XapA_14305	ENOG4107Z5C	methylesterase
XapA_14310	ENOG4105C08	Histidine kinase
XapA_14315	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
XapA_14340	ENOG4105BZU	Histidine kinase
XapA_14350	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
XapA_14355	ENOG4105FUA	antagonist
XapA_14360	ENOG4107MMM	Anti-sigma-factor antagonist
XapA_14370	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
XapA_14385	ENOG4105KAF	membrAne
XapA_14390	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
XapA_14400	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
XapA_14405	ENOG4105CCU	oxidase (Subunit III)
XapA_14410	ENOG4105BZ9	Cytochrome C oxidase, subunit I
XapA_14415	ENOG4105E2S	oxidase) subunit II
XapA_14425	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
XapA_14430	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
XapA_14435	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
XapA_14440	ENOG4105DTN	riboflavin biosynthesis protein ribF
XapA_14445	ENOG4105CJR	Integral membrane protein (MviN
XapA_14455	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
XapA_14460	ENOG4105K46	50S ribosomal protein l27
XapA_14465	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
XapA_14470	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
XapA_14475	ENOG4108TGP	Thioesterase superfamily protein
XapA_14525	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
XapA_14535	ENOG4107SPG	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
XapA_14580	ENOG4105WH1	Two component transcriptional regulator luxr family
XapA_14585	ENOG4105BZU	Histidine kinase
XapA_14600	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
XapA_14605	ENOG4107QMS	site-determining protein
XapA_14620	ENOG4105DHQ	Histidine kinase
XapA_14625	ENOG4105ETX	regulatoR
XapA_14640	ENOG4105DIJ	Phosphoethanolamine transferase
XapA_14655	ENOG4105C2C	drug resistance transporter, Bcr CflA
XapA_14660	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XapA_14665	ENOG4105EBR	Carboxylesterase
XapA_14670	ENOG4105CV8	reductase
XapA_14700	ENOG4106AXJ	AraC family transcriptional regulator
XapA_14760	ENOG4105C3M	thioredoxin reductase
XapA_14770	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
XapA_14775	ENOG4105CWX	Alpha-1,2-mannosidase
XapA_14785	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
XapA_14790	ENOG4105BZP	glycoside hydrolase 15-related
XapA_14800	ENOG4107Z4K	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
XapA_14840	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
XapA_14865	ENOG4107XZC	Restriction modification system DNA (Specificity
XapA_14895	ENOG4108XFH	Transcriptional regulator
XapA_14900	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
XapA_14905	ENOG4105CD8	aminopeptidase N
XapA_14910	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
XapA_14920	ENOG4105EPW	hflc protein
XapA_14925	ENOG4107QJR	hflk protein
XapA_14930	ENOG4105M3Z	response regulator
XapA_14955	ENOG4108JQB	penicillin-binding protein 1C
XapA_14975	ENOG4105DN3	alpha-2-macroglobulin domain protein
XapA_14995	ENOG4105C7F	AcnD-accessory protein PrpF
XapA_15010	ENOG4105YAJ	CopG Arc MetJ
XapA_15015	ENOG4108I0Z	Aconitate hydratase
XapA_15020	ENOG4105BZN	citrate synthase
XapA_15025	ENOG4105CR4	methylisocitrate lyase
XapA_15030	ENOG4108JU7	Transcriptional regulator
XapA_15050	ENOG4107QRG	dna polymerase iii
XapA_15055	ENOG4105HHA	aminodeoxychorismate lyase
XapA_15065	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
XapA_15075	ENOG4105CHR	reductase
XapA_15080	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
XapA_15090	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
XapA_15095	ENOG4105VGS	50s ribosomal protein l32
XapA_15100	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
XapA_15105	ENOG4108UHJ	MAF-like protein
XapA_15135	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
XapA_15145	ENOG4105F8C	transglutaminase domain-containing protein
XapA_15155	ENOG4105K59	histidine triad (HIT) protein
XapA_15160	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
XapA_15165	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
XapA_15170	ENOG4107QMP	dna polymerase iii subunits gamma and tau
XapA_15185	ENOG4108ZAF	Molybdopterin
XapA_15190	ENOG4105M00	molybdopterin converting factor, subunit 1
XapA_15195	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
XapA_15200	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
XapA_15205	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
XapA_15210	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
XapA_15215	ENOG4105DKP	glycosyl transferase, family 9
XapA_15230	ENOG4108ZF3	Phosphatase
XapA_15235	ENOG4107RZZ	dna polymerase iii epsilon subunit
XapA_15240	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
XapA_15250	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
XapA_15255	ENOG41068JE	domain protein
XapA_15260	ENOG4105EIN	peptidylprolyl cis-trans isomerase
XapA_15285	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
XapA_15295	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
XapA_15305	ENOG4105BZU	Histidine kinase
XapA_15335	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
XapA_15345	ENOG4105VW4	glutaredoxin 3
XapA_15350	ENOG4105ERG	peptidase m48, ste24p
XapA_15355	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
XapA_15360	ENOG4105BZU	Histidine kinase
XapA_15365	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
XapA_15370	ENOG4105C9X	ppx gppa phosphatase
XapA_15375	ENOG4105BZF	Glycosyl transferase (Group 1
XapA_15380	ENOG4105EYK	Phosphatidylglycerophosphatase B
XapA_15385	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
XapA_15405	ENOG4105ED9	Protein of unknown function (DUF455)
XapA_15410	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
XapA_15425	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
XapA_15435	ENOG4105CVJ	phosphoglycerate mutase
XapA_15470	ENOG4105CPQ	Dehydrogenase
XapA_15480	ENOG4108IJ6	ABC transporter
XapA_15490	ENOG4108I5D	sulfate abc transporter
XapA_15495	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
XapA_15500	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
XapA_15510	ENOG4108R99	pseudouridine synthase
XapA_15520	ENOG4105CDV	Ompa motb domain protein
XapA_15535	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
XapA_15555	ENOG4108K3A	Glutathione S-transferase
XapA_15565	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
XapA_15570	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
XapA_15575	ENOG4105CI3	gtp-binding protein typa
XapA_15585	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
XapA_15595	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
XapA_15615	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
XapA_15645	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
XapA_15650	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
XapA_15665	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
XapA_15670	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
XapA_15675	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
XapA_15685	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
XapA_15690	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
XapA_15715	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
XapA_15725	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
XapA_15730	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XapA_15740	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
XapA_15745	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
XapA_15750	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
XapA_15755	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
XapA_15760	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
XapA_15765	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
XapA_15775	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
XapA_15780	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
XapA_15785	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
XapA_15790	ENOG4108VZM	50s ribosomal protein L10
XapA_15795	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
XapA_15800	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
XapA_15805	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
XapA_15810	ENOG4105PM1	preprotein translocase subunit SecE
XapA_15820	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
XapA_15840	ENOG4105C3G	gtp-binding protein
XapA_15845	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
XapA_15850	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
XapA_15855	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
XapA_15865	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
XapA_15870	ENOG4105QVB	outer membrane lipoprotein LolB
XapA_15875	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
XapA_15880	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
XapA_15885	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
XapA_15905	ENOG4105CSR	polyphosphate kinase 2
XapA_15925	ENOG4107S2Z	UPF0761 membrane protein
XapA_15930	ENOG4105CS1	NAD(P)H quinone oxidoreductase
XapA_15950	ENOG4108Z66	YbaK ebsC protein
XapA_15955	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
XapA_15965	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
XapA_15975	ENOG4105CM2	brancheD-chain amino acid aminotransferase
XapA_15990	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
XapA_15995	ENOG4105W8H	transhydrogenase (subunit alpha
XapA_16015	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
XapA_16045	ENOG4105C2M	dna polymerase I
XapA_16065	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
XapA_16080	ENOG4105C5Q	Transcriptional regulator
XapA_16090	ENOG4105NXH	GreA GreB family elongation factor
XapA_16095	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
XapA_16105	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
XapA_16120	ENOG4105BZU	Histidine kinase
XapA_16140	ENOG4105CX6	glutaminyL-tRNA synthetase
XapA_16150	ENOG4105DXC	membrane
XapA_16170	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
XapA_16205	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
XapA_16215	ENOG4105CEY	Amp-dependent synthetase and ligase
XapA_16220	ENOG4105DDW	LysR family Transcriptional regulator
XapA_16255	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
XapA_16260	ENOG4105D0A	hydroxylase
XapA_16275	ENOG4108WBT	adenosyltransferase
XapA_16285	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
XapA_16290	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
XapA_16295	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
XapA_16300	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
XapA_16305	ENOG4105NWN	ApaG protein
XapA_16310	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
XapA_16320	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
XapA_16330	ENOG4105DEF	Extracellular solute-binding protein, family 5
XapA_16355	ENOG4108UZX	fmn reductase
XapA_16360	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
XapA_16370	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
XapA_16375	ENOG4105D7T	ABC transporter
XapA_16380	ENOG4107T8P	acyl-Coa dehydrogenase
XapA_16385	ENOG4107SM7	Transcriptional regulator
XapA_16400	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
XapA_16405	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
XapA_16440	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
XapA_16445	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
XapA_16455	ENOG4105EUB	pirin domain protein
XapA_16470	ENOG4105EUB	pirin domain protein
XapA_16475	ENOG4105D22	carbon starvation protein
XapA_16480	ENOG4105VCD	cytoplasmic protein
XapA_16530	ENOG4107XAN	XdhC and CoxI family
XapA_16535	ENOG4105C7W	Xanthine dehydrogenase
XapA_16540	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
XapA_16545	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
XapA_16560	ENOG4108UUM	single-stranded DNA-binding protein
XapA_16565	ENOG4105EAH	synthase
XapA_16580	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
XapA_16595	ENOG4105CFH	Aspartokinase
XapA_16600	ENOG4105JAB	phenazine biosynthesis protein, phzf family
XapA_16615	ENOG4108Z9K	Osmotically inducible protein
XapA_16620	ENOG4105CXT	aspartate transcarbamylase
XapA_16625	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
XapA_16630	ENOG4108UJU	UPF0301 protein
XapA_16640	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
XapA_16650	ENOG4108E16	pectate lyase
XapA_16655	ENOG4105CZX	twitching motility protein
XapA_16660	ENOG4105CZX	twitching motility protein
XapA_16665	ENOG4105DFA	alanine racemase domain protein
XapA_16670	ENOG4105II7	pyrroline-5-carboxylate reductase
XapA_16680	ENOG4105FAA	peptidase M23
XapA_16700	ENOG4108Z0Z	intracellular protease Pfpi family
XapA_16720	ENOG4105C3K	feS assembly ATPase SufC
XapA_16725	ENOG4105JRK	feS assembly protein SufD
XapA_16730	ENOG4105C9B	Cysteine desulfurase
XapA_16740	ENOG4105VQD	rieske 2fe-2S domain-containing protein
XapA_16745	ENOG4108IU3	tonb-dependent siderophore receptor
XapA_16750	ENOG4107E2E	PKHD-type hydroxylase
XapA_16775	ENOG4105CJ2	(LipO)protein
XapA_16780	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
XapA_16795	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
XapA_16810	ENOG4105EHM	Aminoglycoside phosphotransferase
XapA_16815	ENOG4108S0S	Nucleotidyl transferase
XapA_16825	ENOG4105C02	permease
XapA_16835	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
XapA_16845	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
XapA_16865	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
XapA_16875	ENOG4105C2X	Arabinose 5-phosphate isomerase
XapA_16880	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
XapA_16890	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
XapA_16895	ENOG4108IUZ	ABC transporter
XapA_16900	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
XapA_16905	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
XapA_16910	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
XapA_16915	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
XapA_16920	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
XapA_16930	ENOG41080Z8	PHOSPHOCARRIER protein
XapA_16935	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
XapA_16945	ENOG4105CJW	magnesium transporter
XapA_16950	ENOG4107UWA	esterase
XapA_16960	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
XapA_16965	ENOG4105C4M	(Ubiquinol oxidase) subunit I
XapA_16985	ENOG4105C85	amino acid
XapA_16995	ENOG4108NFF	pectate lyase
XapA_17020	ENOG4105CUB	amino acid
XapA_17040	ENOG4108MHS	Lysyl endopeptidase
XapA_17050	ENOG4107XDQ	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
XapA_17110	ENOG4108Z4X	TRANSCRIPTIONal
XapA_17125	ENOG4106032	Glutathionylspermidine synthase
XapA_17150	ENOG4108P9J	Phage shock protein A
XapA_17160	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
XapA_17165	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
XapA_17170	ENOG4105D49	3-dehydroquinate synthase
XapA_17180	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
XapA_17185	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
XapA_17190	ENOG4105BZU	Histidine kinase
XapA_17195	ENOG4105BZU	Histidine kinase
XapA_17205	ENOG4105BZU	Histidine kinase
XapA_17210	ENOG4108YYC	ycei family
XapA_17230	ENOG4105EJQ	L-serine dehydratase
XapA_17245	ENOG4105CFH	Aspartokinase
XapA_17250	ENOG4105C28	cystathionine
XapA_17255	ENOG4106TYC	homoserine o-acetyltransferase (EC 2.3.1.31)
XapA_17260	ENOG4105DR5	peptidase
XapA_17265	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
XapA_17270	ENOG4108UT2	hemolysin iii
XapA_17275	ENOG41066T0	asmA family
XapA_17280	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
XapA_17290	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
XapA_17295	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
XapA_17305	ENOG4105D05	Receptor
XapA_17320	ENOG4108IG5	Transcriptional regulator
XapA_17330	ENOG4107QPN	acyl-Coa dehydrogenase
XapA_17360	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
XapA_17365	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
XapA_17385	ENOG4105KK4	UPF0060 membrane protein
XapA_17390	ENOG4105DXN	mazG family
XapA_17395	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
XapA_17400	ENOG4107RK2	ADP-ribose diphosphatase NudE
XapA_17410	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
XapA_17415	ENOG4105CHC	glucokinase (EC 2.7.1.2)
XapA_17430	ENOG4105VRS	hydrolase family 18
XapA_17450	ENOG4108JJA	ABC, transporter
XapA_17480	ENOG4105CWX	Alpha-1,2-mannosidase
XapA_17520	ENOG4106N3A	copper homeostasis protein cutc
XapA_17540	ENOG4105D9U	N-acetyltransferase
XapA_17560	ENOG4105C8Q	Methyl-accepting chemotaxis
XapA_17570	ENOG4105M3Z	response regulator
XapA_17575	ENOG4108UNF	response regulator
XapA_17580	ENOG4105D7Z	glutathione synthase
XapA_17590	ENOG41065RQ	ADP-ribosylation crystallin J1
XapA_17595	ENOG41072GX	Peptidase M22 Glycoprotease
XapA_17600	ENOG4105DVT	helicase
XapA_17610	ENOG4105BZ4	penicillin-binding protein
XapA_17630	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
XapA_17635	ENOG410698T	Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide (By similarity)
XapA_17640	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
XapA_17645	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
XapA_17650	ENOG4105Z85	coenzyme PQQ synthesis
XapA_17655	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
XapA_17680	ENOG4105CQ7	ATP-dependent helicase
XapA_17695	ENOG4105C9U	ATP-dependent DNA helicase RecQ
XapA_17730	ENOG4105C8Q	Methyl-accepting chemotaxis
XapA_17750	ENOG410903D	sensor protein
XapA_17755	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
XapA_17765	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
XapA_17775	ENOG4105KCK	Peptidoglycan-associated lipoprotein
XapA_17780	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
XapA_17795	ENOG4105E02	MotA TolQ exbB proton channel
XapA_17800	ENOG4107YD3	Thioesterase
XapA_17805	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
XapA_17815	ENOG4105DFH	Transport of potassium into the cell (By similarity)
XapA_17820	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
XapA_17825	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
XapA_17830	ENOG4105CDY	transcriptional regulatory protein
XapA_17845	ENOG4105C9M	aspartyl-trna synthetase
XapA_17860	ENOG4108ISG	Major Facilitator
XapA_17875	ENOG4105HSS	phospholipase C
XapA_17895	ENOG4105ETT	transcriptional Regulator, LysR family
XapA_17905	ENOG4105C5H	ABC transporter
XapA_17910	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
XapA_17930	ENOG4107RNH	Outer membrane receptor FepA
XapA_17945	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
XapA_17970	ENOG4105GAV	receptor
XapA_17995	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
XapA_18025	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
XapA_18030	ENOG4108YZT	Adenosylcobinamide kinase
XapA_18035	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
XapA_18040	ENOG4105EFT	decarboxylase
XapA_18050	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
XapA_18065	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
XapA_18070	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
XapA_18075	ENOG4105E2Y	ABC, transporter
XapA_18080	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
XapA_18085	ENOG4105GVF	(ABC) transporter
XapA_18090	ENOG4105CPC	Aldo Keto reductase
XapA_18100	ENOG4107ZSV	Receptor
XapA_18110	ENOG41082IR	Excinuclease ABC C subunit domain protein
XapA_18145	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
XapA_18155	ENOG4108K4C	ec 3.1.3.12
XapA_18160	ENOG4105BZP	glycoside hydrolase 15-related
XapA_18165	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
XapA_18170	ENOG4105DZG	Dehydrogenase
XapA_18180	ENOG4105C8Q	Methyl-accepting chemotaxis
XapA_18185	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
XapA_18200	ENOG4105C34	Pseudouridine synthase
XapA_18205	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XapA_18215	ENOG4105C4K	Nad synthetase
XapA_18225	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
XapA_18230	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
XapA_18235	ENOG4107TUY	Histidine kinase
XapA_18240	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
XapA_18250	ENOG4107QHF	type ii secretion system protein e
XapA_18260	ENOG4107QHF	type ii secretion system protein e
XapA_18275	ENOG4105D7Q	type ii secretion system
XapA_18280	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
XapA_18285	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
XapA_18295	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
XapA_18300	ENOG4108JJA	ABC, transporter
XapA_18305	ENOG4105CHM	Aminotransferase
XapA_18355	ENOG41069H0	dihydroorotase EC 3.5.2.3
XapA_18360	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
XapA_18395	ENOG4108RMV	DegV Family
XapA_18400	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
XapA_18430	ENOG4105EJG	cellulose synthase
XapA_18435	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
XapA_18440	ENOG4107EEX	Cellulose synthase regulator protein
XapA_18445	ENOG4107QZ7	Cellulose synthase catalytic subunit
XapA_18460	ENOG4107RH7	Nicotinate phosphoribosyltransferase
XapA_18525	ENOG4106S9K	Transcriptional regulator
XapA_18540	ENOG4105GVR	general secretion pathway protein D
XapA_18550	ENOG410678M	general secretion pathway protein M
XapA_18555	ENOG41090VX	general secretion pathway protein L
XapA_18560	ENOG4105UV2	general secretion pathway protein K
XapA_18565	ENOG41069G9	General secretion pathway protein J
XapA_18575	ENOG4105WMT	general secretion pathway protein h
XapA_18585	ENOG4105D7Q	type ii secretion system
XapA_18595	ENOG4107QHF	type ii secretion system protein e
XapA_18600	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
XapA_18605	ENOG4105EUR	Domain-Containing protein
XapA_18610	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
XapA_18615	ENOG4105EUR	Domain-Containing protein
XapA_18620	ENOG4108ETH	Formylglycinamide ribotide synthetase
XapA_18630	ENOG4105T95	Thiol disulfide interChange protein
XapA_18640	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
XapA_18655	ENOG4108K5H	permease YjgP YjgQ family protein
XapA_18665	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
XapA_18680	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
XapA_18695	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
XapA_18700	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
XapA_18720	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
XapA_18730	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
XapA_18735	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
XapA_18750	ENOG4105DHJ	ABC, transporter
XapA_18755	ENOG4108SNX	Mammalian cell entry related domain protein
XapA_18770	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
XapA_18790	ENOG4107QKV	phosphomannomutase
XapA_18795	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
XapA_18805	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
XapA_18810	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
XapA_18825	ENOG4105BZJ	Electron transfer flavoprotein
XapA_18830	ENOG4105C10	Electron transfer flavoprotein
XapA_18845	ENOG4105IQ5	FAD linked oxidase domain protein
XapA_18860	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
XapA_18905	ENOG4105EY8	ABC transporter
XapA_18915	ENOG4105C28	cystathionine
XapA_18940	ENOG4105CZX	twitching motility protein
XapA_18945	ENOG4108RXX	maleylacetoacetate isomerase
XapA_18960	ENOG4105C1J	atp-dependent rna helicase
XapA_18970	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
XapA_18980	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
XapA_18990	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
XapA_19010	ENOG4105NIV	Esterase
XapA_19015	ENOG4107RNH	Outer membrane receptor FepA
XapA_19020	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
XapA_19025	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
XapA_19030	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
XapA_19045	ENOG4105DGW	oligopeptidase A
XapA_19060	ENOG4105E3B	Multicopper oxidase
XapA_19100	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
XapA_19105	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
XapA_19110	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
XapA_19115	ENOG4107RBB	ABC transporter, permease
XapA_19120	ENOG4107RBB	ABC transporter, permease
XapA_19135	ENOG4105BZU	Histidine kinase
XapA_19140	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
XapA_19155	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
XapA_19160	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
XapA_19165	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
XapA_19170	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
XapA_19175	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
XapA_19180	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
XapA_19185	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
XapA_19190	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
XapA_19210	ENOG4107QN2	dihydrolipoyl dehydrogenase
XapA_19220	ENOG4107QSN	dihydrolipoamide acetyltransferase
XapA_19260	ENOG4105D01	(LipO)protein
XapA_19265	ENOG4108UMI	ABC transporter, permease
XapA_19270	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
XapA_19275	ENOG4108EHX	EamA-like transporter family
XapA_19280	ENOG4108VPT	UPF0234 protein
XapA_19290	ENOG4105BZU	Histidine kinase
XapA_19310	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
XapA_19315	ENOG4107YBY	Hydrolase
XapA_19320	ENOG4105I08	Pseudouridine synthase
XapA_19325	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
XapA_19345	ENOG4105BZU	Histidine kinase
XapA_19365	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
XapA_19370	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
XapA_19375	ENOG4105EW9	transcriptional regulator AsnC family
XapA_19395	ENOG4107RD7	Flagellar Motor Protein, MotA
XapA_19400	ENOG4105ER2	Ompa motb domain protein
XapA_19435	ENOG4105E3A	(ABC) transporter
XapA_19445	ENOG4105EEQ	Na H antiporter
XapA_19460	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
XapA_19470	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
XapA_19490	ENOG4105CPC	Aldo Keto reductase
XapA_19500	ENOG4106WTF	Glycosyl transferase, family 2
XapA_19505	ENOG4105C9K	Endothelin-converting enzyme 1
XapA_19525	ENOG4107QTZ	amino acid
XapA_19535	ENOG4108VAC	response regulator
XapA_19540	ENOG4105C2F	Histidine kinase
XapA_19565	ENOG4108Z9Z	response to DNA damage stimulus
XapA_19570	ENOG4105WEF	catalase
XapA_19590	ENOG4105BZU	Histidine kinase
XapA_19605	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
XapA_19620	ENOG4105C4M	(Ubiquinol oxidase) subunit I
XapA_19625	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
XapA_19645	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
XapA_19650	ENOG4105CMR	udp-glucose 4-epimerase
XapA_19680	ENOG4105BZ1	(ABC) transporter
XapA_19705	ENOG4105E2A	Dehydrogenase
XapA_19765	ENOG4105CIG	ABC transporter
XapA_19780	ENOG4108UQ8	endoribonuclease L-psp
XapA_19795	ENOG4105C8Q	Methyl-accepting chemotaxis
XapA_19810	ENOG4105HEI	LysR family (Transcriptional regulator
XapA_19815	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
XapA_19890	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
XapA_19895	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
XapA_19900	ENOG4105D1S	lipid A biosynthesis
XapA_19910	ENOG4108Z7F	N-acetyltransferase
XapA_19955	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
XapA_19960	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
XapA_19965	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
XapA_19970	ENOG4108WZM	domain protein
XapA_19975	ENOG4105C79	DNA protecting protein DprA
XapA_19995	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
XapA_20000	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
XapA_20015	ENOG4107ZQV	short-chain dehydrogenase reductase
XapA_20025	ENOG4105D07	Signal peptide peptidase, SppA
XapA_20030	ENOG4107QI1	Mate efflux family protein
XapA_20050	ENOG4105C25	Primosomal protein n'
XapA_20055	ENOG4108TGY	Glutathione S-transferase
XapA_20080	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
XapA_20085	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
XapA_20090	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
XapA_20095	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
XapA_20100	ENOG4105CAK	Cell division ATP-binding protein ftsE
XapA_20105	ENOG4105C1J	atp-dependent rna helicase
XapA_20115	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
XapA_20120	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
XapA_20125	ENOG4105ETT	transcriptional Regulator, LysR family
XapA_20135	ENOG4105E9K	Isocitrate dehydrogenase
XapA_20150	ENOG4105FB9	CRISPR-associated protein
XapA_20170	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
XapA_20175	ENOG4105KCF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
XapA_20185	ENOG4109066	lysm domain bon superfamily protein
XapA_20190	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
XapA_20195	ENOG4105CH2	amidohydrolase
XapA_20200	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
XapA_20205	ENOG4105BZS	acriflavin resistance protein
XapA_20215	ENOG4105E32	cytoplasmic protein
XapA_20270	ENOG4108UQS	dipeptidase
XapA_20275	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
XapA_20285	ENOG4105DTQ	mandelate racemase muconate lactonizing
XapA_20295	ENOG4105D5Q	Arginine ornithine antiporter
XapA_20310	ENOG4108Z12	YiaAB two helix domain-containing protein
XapA_20320	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
XapA_20325	ENOG4107ZVW	dihydroneopterin aldolase
XapA_20330	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
XapA_20340	ENOG4105KTH	gatB Yqey
XapA_20350	ENOG4107S2Z	UPF0761 membrane protein
XapA_20355	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
XapA_20360	ENOG4105DHU	Bile acid
XapA_20370	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
XapA_20395	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
XapA_20400	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
XapA_20415	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
XapA_20425	ENOG4105C26	Dehydrogenase
XapA_20455	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
XapA_20460	ENOG4105DR5	peptidase
XapA_20465	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
XapA_20475	ENOG4105EYM	Major Facilitator superfamily
XapA_20480	ENOG4105CGK	Exodeoxyribonuclease III
XapA_20485	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
XapA_20495	ENOG4107QJE	Chromosome Partitioning Protein
XapA_20500	ENOG4105FA0	parb-like partition protein
XapA_20520	ENOG4105CKK	Glycosyl transferase, family 2
XapA_20535	ENOG4107QKV	phosphomannomutase
XapA_20540	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
XapA_20545	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
XapA_20550	ENOG4105W5Q	DNA repair protein (RadC
XapA_20555	ENOG4105C75	arginyL-tRNA synthetase
XapA_20570	ENOG4105EMU	Dehydrogenase
XapA_20575	ENOG4105EXC	Acyl-transferase
XapA_20585	ENOG4105CEY	Amp-dependent synthetase and ligase
XapA_20590	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
XapA_20595	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
XapA_20640	ENOG4108YZA	Nitrogen regulatory protein pii
XapA_20645	ENOG4105W0Z	cytoplasmic protein
XapA_20650	ENOG4105C0P	Mg chelatase subunit ChlI
XapA_20665	ENOG41066DG	(EAL) domain protein
XapA_20680	ENOG4105EJ2	Transcriptional regulator
XapA_20700	ENOG4105E0Y	RtcB Protein
XapA_20735	ENOG4105ECP	epimerase
XapA_20740	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
XapA_20745	ENOG4105DHQ	Histidine kinase
XapA_20775	ENOG4105C0H	protease
XapA_20795	ENOG4105DSF	transport protein
XapA_20800	ENOG4107URF	beta-phospho-glucomutase
XapA_20805	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
XapA_20820	ENOG4107VGR	Catalase
XapA_20845	ENOG4108S01	response regulator
XapA_20850	ENOG4108ZGX	Histidine kinase
XapA_20855	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
XapA_20860	ENOG4105C19	ABC transporter
XapA_20885	ENOG4105FDR	Membrane
XapA_20905	ENOG4108NNI	Beta-lactamase domain-containing protein
XapA_20910	ENOG4105C31	Tryptophanyl-tRNA synthetase
XapA_20915	ENOG4105VDW	Csbd family
XapA_21015	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
XapA_21045	ENOG4105EB3	Histidine kinase
XapA_21050	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
XapA_21060	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
XapA_21080	ENOG4105CH6	catalase
XapA_21090	ENOG4105DVT	helicase
XapA_21105	ENOG4105E2X	shikimate dehydrogenase
XapA_21115	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
XapA_21140	ENOG4105D52	delta-aminolevulinic acid dehydratase
XapA_21170	ENOG4105CYM	Glutathione S-transferase
XapA_21210	ENOG4108IUW	ABC transporter
XapA_21220	ENOG4105VZ8	Transcriptional regulator
XapA_21240	ENOG4105PGM	cation diffusion facilitator family transporter
XapA_21250	ENOG4105E0K	tonB-dependent siderophore receptor
XapA_21260	ENOG4105ECQ	AraC Family Transcriptional Regulator
XapA_21265	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
XapA_21270	ENOG4105DA5	(ABC) transporter
XapA_21275	ENOG4105E3A	(ABC) transporter
XapA_21285	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
XapA_21320	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
XapA_21330	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
XapA_21345	ENOG4105CD5	CoA-binding domain protein
XapA_21350	ENOG4105CJW	magnesium transporter
XapA_21370	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
XapA_21375	ENOG4105BZP	glycoside hydrolase 15-related
XapA_21395	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
XapA_21405	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
XapA_21455	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
XapA_21460	ENOG4105E9Q	Acyl-transferase
XapA_21470	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
XapA_21500	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
XapA_21520	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
XapA_21530	ENOG4105C2M	dna polymerase I
XapA_21560	ENOG4107TPY	serine threonine protein kinase
XapA_21565	ENOG4108ZF3	Phosphatase
XapA_21600	ENOG4105CS6	Rhs element vgr protein
XapA_21645	ENOG4105D6F	Phosphatase
XapA_21715	ENOG4108WC9	type VI secretion system effector, hcp1 family
XapA_21760	ENOG4105C4R	Atp-dependent dna helicase
XapA_21775	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
XapA_21780	ENOG4108KB2	LysR family Transcriptional regulator
XapA_21785	ENOG4105JSC	dimethylmenaquinone methyltransferase
XapA_21800	ENOG4105KHM	amidohydrolase 2
XapA_21830	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
XapA_21850	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
XapA_21855	ENOG4105DGI	Alkaline phosphatase
XapA_21880	ENOG4105CGK	Exodeoxyribonuclease III
XapA_21885	ENOG4105E2R	ROK family
XapA_21895	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
XapA_21905	ENOG4107QN1	sodium solute
XapA_21910	ENOG41062QD	Membrane
XapA_21920	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
XapA_21960	ENOG4105DSG	hydrolase family 43
XapA_21980	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
XapA_21985	ENOG4105ERH	Fumarylacetoacetate hydrolase
XapA_21995	ENOG4105DIA	mandelate racemase muconate lactonizing
XapA_22000	ENOG4105QJH	Domain of unknown function (DUF718)
XapA_22005	ENOG4105EDR	glucose galactose transporter
XapA_22010	ENOG4108K2P	TRANSCRIPTIONal
XapA_22020	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
XapA_22025	ENOG4105BZU	Histidine kinase
XapA_22040	ENOG4105E2V	Glycosyltransferase 36
XapA_22045	ENOG4105CT4	transporter
XapA_22050	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
XapA_22080	ENOG4105MA0	exported protein
XapA_22085	ENOG4105CFU	surface antigen
XapA_22135	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
XapA_22155	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
XapA_22165	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
XapA_22170	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
XapA_22185	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
XapA_22210	ENOG4105DH7	May be involved in recombination (By similarity)
XapA_22215	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
XapA_22225	ENOG4105C93	Xylose Isomerase
XapA_22230	ENOG4105ETE	Transcriptional regulator (LacI family
XapA_22245	ENOG4105CXK	mandelate racemase muconate lactonizing
XapA_22260	ENOG4105DEI	Mannitol dehydrogenase
XapA_22305	ENOG4105EVH	UPF0753 protein
XapA_22360	ENOG4108C33	Resolvase
XapA_22410	ENOG4106RHG	Yeca family
XapA_22430	ENOG4108C33	Resolvase
XapA_22450	ENOG41082W1	Cupin 2, conserved barrel domain protein
XapA_22465	ENOG4105CGF	Aromatic amino acid aminotransferase
XapA_22470	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
XapA_22500	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
XapA_22540	ENOG4105CSH	Transporter
XapA_22550	ENOG4105K63	Thioredoxin
XapA_22575	ENOG4105D4Y	metalloprotease
XapA_22595	ENOG41067RQ	csbd family
XapA_22695	ENOG4108SIC	Transcriptional regulator
XapA_22705	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
XapA_22755	ENOG4105F2I	Transposase
XapA_22775	ENOG4107QKA	exodeoxyribonuclease V beta
XapA_22780	ENOG4105DSY	exodeoxyribonuclease V, gamma
XapA_22795	ENOG4105DHJ	ABC, transporter
XapA_22800	ENOG4105CY3	ABC transporter, permease
XapA_22805	ENOG4107PE3	Mammalian cell entry related domain protein
XapA_22820	ENOG410903C	(LipO)protein
XapA_22830	ENOG4108V06	Glutathione peroxidase
XapA_22840	ENOG4107QSV	RmuC domain protein
XapA_22845	ENOG4105CIS	alcohol dehydrogenase
XapA_22850	ENOG4105EJC	lysr family transcriptional regulator
XapA_22865	ENOG4108TGY	Glutathione S-transferase
XapA_22875	ENOG4105CUB	amino acid
XapA_22890	ENOG4105NRM	Membrane
XapA_22920	ENOG4105DR4	Methyltransferase
XapA_22930	ENOG4105DU1	integral membrane protein, terc
XapA_22945	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
XapA_22960	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
XapA_22965	ENOG4108ZJ4	polysaccharide deacetylase
XapA_22970	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
XapA_22975	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
XapA_23075	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
XapA_23190	ENOG4105C26	Dehydrogenase
XapA_23255	ENOG4108NSC	Pfam:DUF88
XapA_23315	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
XapA_23390	ENOG4105C26	Dehydrogenase
XapA_23430	ENOG4105C0H	protease
XapA_23725	ENOG4105CMA	conjugation trbi family protein