locus-tag	class	description
DOO79_00050	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DOO79_00050	COG0546	phosphoglycolate phosphatase activity
DOO79_00070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DOO79_00105	COG1216	Glycosyl transferase, family 2
DOO79_00105	COG0438	transferase activity, transferring glycosyl groups
DOO79_00125	COG0626	cystathionine gamma-synthase activity
DOO79_00155	COG0625	glutathione transferase activity
DOO79_00170	COG0513	Belongs to the DEAD box helicase family
DOO79_00180	COG4206	TonB-dependent receptor
DOO79_00190	COG0720	synthase
DOO79_00200	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DOO79_00210	COG1956	GAF domain-containing protein
DOO79_00220	COG2819	hydrolase of the alpha beta superfamily
DOO79_00235	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DOO79_00240	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DOO79_00255	COG0339	signal peptide processing
DOO79_00270	COG2132	Multicopper oxidase
DOO79_00310	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DOO79_00315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DOO79_00320	COG4591	ABC-type transport system involved in lipoprotein release permease component
DOO79_00320	COG1136	(ABC) transporter
DOO79_00325	COG0577	efflux transmembrane transporter activity
DOO79_00330	COG0577	efflux transmembrane transporter activity
DOO79_00345	COG4191	Histidine kinase
DOO79_00350	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DOO79_00365	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DOO79_00370	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DOO79_00375	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DOO79_00380	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DOO79_00385	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DOO79_00390	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DOO79_00400	COG0356	it plays a direct role in the translocation of protons across the membrane
DOO79_00420	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DOO79_00430	COG0508	dehydrogenase complex catalyzes the overall conversion of
DOO79_00475	COG2011	ABC-type metal ion transport system permease component
DOO79_00480	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DOO79_00485	COG0697	spore germination
DOO79_00490	COG1666	GTP binding
DOO79_00500	COG2198	Histidine kinase
DOO79_00500	COG5002	protein histidine kinase activity
DOO79_00500	COG0784	Response regulator, receiver
DOO79_00525	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DOO79_00530	COG1187	pseudouridine synthase activity
DOO79_00535	COG2813	Specifically methylates the guanine in position
DOO79_00555	COG2205	protein histidine kinase activity
DOO79_00555	COG2202	Pas domain
DOO79_00575	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DOO79_00580	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DOO79_00645	COG0842	Transport permease protein
DOO79_00655	COG0025	NhaP-type Na H and K H
DOO79_00665	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
DOO79_00670	COG1573	uracil-dna glycosylase
DOO79_00680	COG3384	dioxygenase
DOO79_00700	COG0667	Aldo Keto reductase
DOO79_00715	COG3590	peptidase
DOO79_00735	COG0531	amino acid
DOO79_00750	COG2972	Histidine kinase
DOO79_00775	COG3685	Protein conserved in bacteria
DOO79_00780	COG3546	catalase activity
DOO79_00830	COG1271	oxidase subunit
DOO79_00835	COG1294	oxidase, subunit
DOO79_00855	COG1028	Short-chain dehydrogenase reductase Sdr
DOO79_00860	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DOO79_00890	COG1132	(ABC) transporter
DOO79_00915	COG1063	alcohol dehydrogenase
DOO79_00990	COG0251	oxidation-reduction process
DOO79_01005	COG0840	transmembrane signaling receptor activity
DOO79_01020	COG0583	DNA-binding transcription factor activity
DOO79_01025	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DOO79_01100	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DOO79_01105	COG1490	D-aminoacyl-tRNA deacylase activity
DOO79_01110	COG1560	Kdo2-lipid A biosynthetic process
DOO79_01165	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DOO79_01165	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DOO79_01170	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DOO79_01175	COG0242	peptide deformylase activity
DOO79_01180	COG1652	LysM domain
DOO79_01185	COG0758	DNA mediated transformation
DOO79_01205	COG1754	DNA topoisomerase type I activity
DOO79_01205	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DOO79_01210	COG0009	L-threonylcarbamoyladenylate synthase
DOO79_01225	COG1028	Short-chain dehydrogenase reductase Sdr
DOO79_01240	COG0616	signal peptide processing
DOO79_01245	COG0534	Mate efflux family protein
DOO79_01265	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DOO79_01270	COG0625	glutathione transferase activity
DOO79_01285	COG1252	NADH dehydrogenase
DOO79_01295	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DOO79_01300	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DOO79_01305	COG3437	response regulator, receiver
DOO79_01310	COG2177	Part of the ABC transporter FtsEX involved in
DOO79_01315	COG2884	Cell division ATP-binding protein ftsE
DOO79_01320	COG0513	Belongs to the DEAD box helicase family
DOO79_01325	COG3118	belongs to the thioredoxin family
DOO79_01330	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DOO79_01335	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
DOO79_01340	COG0583	DNA-binding transcription factor activity
DOO79_01385	COG1518	maintenance of DNA repeat elements
DOO79_01390	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DOO79_01400	COG1652	LysM domain
DOO79_01405	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DOO79_01405	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DOO79_01410	COG1473	amidohydrolase
DOO79_01415	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DOO79_01420	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DOO79_01430	COG5383	Protein conserved in bacteria
DOO79_01485	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
DOO79_01490	COG3023	N-Acetylmuramoyl-L-alanine amidase
DOO79_01500	COG4948	Mandelate Racemase Muconate Lactonizing
DOO79_01510	COG0531	amino acid
DOO79_01525	COG4682	membrane
DOO79_01530	COG2133	pyrroloquinoline quinone binding
DOO79_01540	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DOO79_01545	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DOO79_01555	COG1610	YqeY-like protein
DOO79_01565	COG1295	ribonuclease BN
DOO79_01570	COG0358	DNA primase activity
DOO79_01585	COG0109	protoheme IX farnesyltransferase activity
DOO79_01615	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
DOO79_01630	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DOO79_01670	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DOO79_01675	COG0739	heme binding
DOO79_01680	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
DOO79_01690	COG2211	Major facilitator Superfamily
DOO79_01695	COG0708	Exodeoxyribonuclease III
DOO79_01700	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DOO79_01710	COG1192	Involved in chromosome partitioning
DOO79_01715	COG1475	DNA binding
DOO79_01735	COG0463	Glycosyl transferase, family 2
DOO79_01755	COG0756	dUTP diphosphatase activity
DOO79_01760	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DOO79_01765	COG2003	Belongs to the UPF0758 family
DOO79_01770	COG0018	arginyl-trna synthetase
DOO79_01785	COG4221	oxidoreductase activity
DOO79_01790	COG2755	lipolytic protein G-D-S-L family
DOO79_01790	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DOO79_01800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DOO79_01805	COG1166	arginine decarboxylase activity
DOO79_01810	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DOO79_01860	COG2960	long-chain fatty acid transporting porin activity
DOO79_01865	COG0606	chelatase, subunit chli
DOO79_01880	COG4943	cyclic-guanylate-specific phosphodiesterase activity
DOO79_01915	COG1690	Belongs to the RtcB family
DOO79_01950	COG1090	epimerase
DOO79_01955	COG0745	RESPONSE REGULATOR receiver
DOO79_01960	COG0642	Histidine kinase
DOO79_01990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DOO79_02015	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DOO79_02020	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DOO79_02035	COG0753	catalase activity
DOO79_02060	COG2197	response regulator
DOO79_02065	COG4585	Histidine kinase
DOO79_02070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DOO79_02075	COG1136	(ABC) transporter
DOO79_02100	COG0697	spore germination
DOO79_02120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DOO79_02125	COG0180	Tryptophanyl-tRNA synthetase
DOO79_02130	COG3237	CsbD-like
DOO79_02175	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DOO79_02225	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DOO79_02230	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
DOO79_02230	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
DOO79_02260	COG2205	protein histidine kinase activity
DOO79_02265	COG0745	RESPONSE REGULATOR receiver
DOO79_02275	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DOO79_02305	COG1199	ATP-dependent helicase activity
DOO79_02320	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DOO79_02385	COG0625	glutathione transferase activity
DOO79_02425	COG4555	ABC transporter
DOO79_02435	COG1476	TRANSCRIPTIONal
DOO79_02480	COG0543	2 iron, 2 sulfur cluster binding
DOO79_02480	COG0633	Ferredoxin
DOO79_02485	COG1131	(ABC) transporter
DOO79_02490	COG0842	Transport permease protein
DOO79_02500	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DOO79_02535	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DOO79_02545	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DOO79_02560	COG0045	succinate-CoA ligase (ADP-forming) activity
DOO79_02560	COG1042	CoA-binding domain protein
DOO79_02560	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DOO79_02565	COG2239	Acts as a magnesium transporter
DOO79_02585	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DOO79_02590	COG3387	PFAM Glycoside hydrolase 15-related
DOO79_02605	COG3100	YcgL domain-containing protein
DOO79_02610	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DOO79_02620	COG0463	Glycosyl transferase, family 2
DOO79_02630	COG1028	Short-chain dehydrogenase reductase Sdr
DOO79_02670	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DOO79_02685	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DOO79_02715	COG4946	Tricorn protease homolog
DOO79_02715	COG1506	peptidase
DOO79_02715	COG0823	Involved in the tonB-independent uptake of proteins
DOO79_02735	COG0408	coproporphyrinogen oxidase activity
DOO79_02780	COG0631	protein serine/threonine phosphatase activity
DOO79_02815	COG3501	Rhs element vgr protein
DOO79_02975	COG0210	DNA helicase
DOO79_02990	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DOO79_02995	COG0583	DNA-binding transcription factor activity
DOO79_03000	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DOO79_03015	COG2159	amidohydrolase
DOO79_03045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DOO79_03065	COG0357	Ribosomal RNA small subunit methyltransferase G
DOO79_03070	COG3540	Alkaline phosphatase
DOO79_03080	COG2091	lysine biosynthetic process via aminoadipic acid
DOO79_03095	COG0708	Exodeoxyribonuclease III
DOO79_03100	COG1940	carbohydrate kinase activity
DOO79_03100	COG1846	Transcriptional regulator
DOO79_03110	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DOO79_03120	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DOO79_03125	COG3162	membrane
DOO79_03135	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DOO79_03175	COG3507	Belongs to the glycosyl hydrolase 43 family
DOO79_03195	COG1028	Short-chain dehydrogenase reductase Sdr
DOO79_03200	COG0179	Fumarylacetoacetate (FAA) hydrolase
DOO79_03210	COG4948	Mandelate Racemase Muconate Lactonizing
DOO79_03215	COG3254	rhamnose metabolic process
DOO79_03220	COG0738	Major facilitator superfamily
DOO79_03225	COG1414	Transcriptional regulator
DOO79_03235	COG1971	Probably functions as a manganese efflux pump
DOO79_03240	COG2205	protein histidine kinase activity
DOO79_03255	COG3459	Glycosyltransferase 36 associated
DOO79_03260	COG2211	Major facilitator Superfamily
DOO79_03265	COG3265	gluconokinase activity
DOO79_03295	COG2911	Protein conserved in bacteria
DOO79_03300	COG0729	surface antigen
DOO79_03350	COG0752	glycyl-tRNA synthetase alpha subunit
DOO79_03370	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DOO79_03370	COG0519	Catalyzes the synthesis of GMP from XMP
DOO79_03380	COG0805	protein transport
DOO79_03385	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DOO79_03390	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DOO79_03400	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DOO79_03425	COG2974	May be involved in recombination
DOO79_03430	COG0037	tRNA processing
DOO79_03440	COG2115	Belongs to the xylose isomerase family
DOO79_03460	COG4948	Mandelate Racemase Muconate Lactonizing
DOO79_03470	COG1472	Belongs to the glycosyl hydrolase 3 family
DOO79_03475	COG0246	Mannitol dehydrogenase
DOO79_03520	COG3002	Belongs to the UPF0753 family
DOO79_03575	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DOO79_03625	COG3012	SEC-C Motif Domain Protein
DOO79_03625	COG3318	Belongs to the UPF0149 family
DOO79_03665	COG0662	Cupin 2, conserved barrel domain protein
DOO79_03685	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
DOO79_03715	COG0714	Associated with various cellular activities
DOO79_03755	COG0477	Major facilitator Superfamily
DOO79_03765	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DOO79_03810	COG3237	CsbD-like
DOO79_03870	COG0564	pseudouridine synthase activity
DOO79_03910	COG1309	transcriptional regulator
DOO79_03920	COG1028	Short-chain dehydrogenase reductase Sdr
DOO79_03970	COG3039	Transposase
DOO79_03995	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
DOO79_04010	COG1127	ABC transporter
DOO79_04015	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DOO79_04020	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DOO79_04035	COG2853	Lipoprotein
DOO79_04045	COG0386	Belongs to the glutathione peroxidase family
DOO79_04055	COG1322	Protein conserved in bacteria
DOO79_04060	COG0604	alcohol dehydrogenase
DOO79_04065	COG0583	DNA-binding transcription factor activity
DOO79_04080	COG0625	glutathione transferase activity
DOO79_04090	COG0531	amino acid
DOO79_04135	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DOO79_04145	COG0861	Integral membrane protein TerC family
DOO79_04160	COG0584	glycerophosphoryl diester phosphodiesterase
DOO79_04175	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DOO79_04180	COG0726	polysaccharide deacetylase
DOO79_04185	COG0706	membrane insertase activity
DOO79_04190	COG0594	ribonuclease P activity
DOO79_04200	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DOO79_04210	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DOO79_04215	COG0187	DNA topoisomerase II activity
DOO79_04225	COG0501	Belongs to the peptidase M48B family
DOO79_04255	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DOO79_04265	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DOO79_04320	COG0793	Belongs to the peptidase S41A family
DOO79_04325	COG4942	peptidase
DOO79_04335	COG2234	aminopeptidase activity
DOO79_04345	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DOO79_04355	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DOO79_04365	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DOO79_04375	COG1064	alcohol dehydrogenase
DOO79_04380	COG0493	'glutamate synthase
DOO79_04385	COG0067	glutamate synthase
DOO79_04385	COG0070	glutamate synthase
DOO79_04385	COG0069	glutamate synthase activity
DOO79_04435	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DOO79_04465	COG0297	glycogen (starch) synthase activity
DOO79_04465	COG0438	transferase activity, transferring glycosyl groups
DOO79_04515	COG1132	(ABC) transporter
DOO79_04545	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DOO79_04645	COG1205	dead DEAH box helicase
DOO79_04645	COG1111	helicase
DOO79_04650	COG1272	protein, Hemolysin III
DOO79_04670	COG0300	oxidoreductase activity
DOO79_04675	COG1028	Short-chain dehydrogenase reductase Sdr
DOO79_04690	COG2249	NAD(P)H dehydrogenase (quinone) activity
DOO79_04700	COG1487	ribonuclease activity
DOO79_04705	COG4691	Plasmid stability protein
DOO79_04725	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DOO79_04735	COG0477	Major facilitator Superfamily
DOO79_04740	COG1289	transmembrane transporter activity
DOO79_04750	COG1566	PFAM secretion protein HlyD family protein
DOO79_04765	COG0302	gtp cyclohydrolase
DOO79_04800	COG0676	glucose-6-phosphate 1-epimerase activity
DOO79_04825	COG3135	benzoate transporter
DOO79_04855	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DOO79_04875	COG0210	DNA helicase
DOO79_04890	COG3132	Protein of unknown function, DUF480
DOO79_04900	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
DOO79_04905	COG0284	orotidine-5'-phosphate decarboxylase activity
DOO79_04940	COG2937	Belongs to the GPAT DAPAT family
DOO79_04975	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DOO79_05060	COG0366	Alpha amylase catalytic
DOO79_05065	COG0366	Alpha amylase catalytic
DOO79_05070	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DOO79_05090	COG0657	acetylesterase activity
DOO79_05090	COG2755	lipolytic protein G-D-S-L family
DOO79_05100	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DOO79_05115	COG3507	Belongs to the glycosyl hydrolase 43 family
DOO79_05120	COG1609	Transcriptional regulator
DOO79_05130	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
DOO79_05135	COG1028	Short-chain dehydrogenase reductase Sdr
DOO79_05145	COG2755	lipolytic protein G-D-S-L family
DOO79_05160	COG3186	Phenylalanine-4-hydroxylase
DOO79_05165	COG1522	sequence-specific DNA binding
DOO79_05175	COG1752	Esterase of the alpha-beta hydrolase superfamily
DOO79_05185	COG1119	ATPase activity
DOO79_05200	COG1125	glycine betaine transport
DOO79_05215	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DOO79_05270	COG0489	protein tyrosine kinase activity
DOO79_05275	COG2062	phosphohistidine phosphatase, SixA
DOO79_05285	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DOO79_05335	COG1968	undecaprenyl-diphosphatase activity
DOO79_05345	COG0174	glutamine synthetase
DOO79_05350	COG0347	Belongs to the P(II) protein family
DOO79_05355	COG0004	ammonium transporteR
DOO79_05360	COG3852	Histidine kinase
DOO79_05365	COG2204	response regulator
DOO79_05370	COG2032	superoxide dismutase activity
DOO79_05375	COG2032	superoxide dismutase activity
DOO79_05390	COG0183	Belongs to the thiolase family
DOO79_05425	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DOO79_05430	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
DOO79_05435	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DOO79_05490	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DOO79_05495	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DOO79_05500	COG4786	Flagellar basal body rod
DOO79_05505	COG4786	Flagellar basal body rod
DOO79_05520	COG1706	bacterial-type flagellum-dependent cell motility
DOO79_05535	COG1677	Flagellar hook-basal body complex protein FliE
DOO79_05540	COG1766	The M ring may be actively involved in energy transduction
DOO79_05555	COG1157	protein secretion by the type III secretion system
DOO79_05580	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DOO79_05615	COG0028	Belongs to the TPP enzyme family
DOO79_05620	COG2205	protein histidine kinase activity
DOO79_05645	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DOO79_05660	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DOO79_05670	COG0596	Alpha beta hydrolase
DOO79_05675	COG0727	PFAM Uncharacterised protein family (UPF0153)
DOO79_05680	COG0318	PFAM AMP-dependent synthetase and ligase
DOO79_05685	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DOO79_05700	COG1181	Belongs to the D-alanine--D-alanine ligase family
DOO79_05710	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DOO79_05720	COG0564	pseudouridine synthase activity
DOO79_05740	COG1446	asparaginase
DOO79_05745	COG0339	signal peptide processing
DOO79_05775	COG0475	glutathione-regulated potassium exporter activity
DOO79_05780	COG0583	DNA-binding transcription factor activity
DOO79_05785	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DOO79_05790	COG2224	Isocitrate lyase
DOO79_05795	COG3706	GGDEF domain
DOO79_05830	COG4770	biotin carboxylase activity
DOO79_05835	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DOO79_05840	COG1960	acyl-CoA dehydrogenase activity
DOO79_05845	COG1309	transcriptional regulator
DOO79_05900	COG0523	cobalamin synthesis protein
DOO79_05920	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DOO79_05925	COG1846	Transcriptional regulator
DOO79_05930	COG1764	response to oxidative stress
DOO79_05960	COG2130	NADP-dependent
DOO79_05975	COG1187	pseudouridine synthase activity
DOO79_05990	COG1643	Atp-dependent helicase
DOO79_05995	COG4807	Protein conserved in bacteria
DOO79_06000	COG2351	hydroxyisourate hydrolase activity
DOO79_06005	COG2072	flavoprotein involved in K transport
DOO79_06025	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DOO79_06060	COG1957	nucleoside hydrolase
DOO79_06070	COG2252	PERMEase
DOO79_06095	COG0084	hydrolase, TatD family'
DOO79_06120	COG2814	Major facilitator Superfamily
DOO79_06135	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DOO79_06140	COG1902	pentaerythritol trinitrate reductase activity
DOO79_06160	COG0745	RESPONSE REGULATOR receiver
DOO79_06165	COG2205	protein histidine kinase activity
DOO79_06170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DOO79_06195	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DOO79_06200	COG0583	DNA-binding transcription factor activity
DOO79_06235	COG0702	epimerase
DOO79_06240	COG1733	regulation of RNA biosynthetic process
DOO79_06360	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DOO79_06365	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DOO79_06395	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DOO79_06400	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DOO79_06410	COG3485	protocatechuate 3,4-dioxygenase
DOO79_06425	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DOO79_06430	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DOO79_06440	COG1414	Transcriptional regulator
DOO79_06460	COG0445	tRNA wobble uridine modification
DOO79_06500	COG2267	carboxylic ester hydrolase activity
DOO79_06510	COG0156	8-amino-7-oxononanoate synthase activity
DOO79_06515	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DOO79_06520	COG1040	competence protein
DOO79_06525	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DOO79_06615	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DOO79_06685	COG3264	Mechanosensitive ion channel
DOO79_06685	COG1511	domain protein
DOO79_06690	COG1368	sulfuric ester hydrolase activity
DOO79_06700	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DOO79_06705	COG2354	Protein conserved in bacteria
DOO79_06715	COG0297	glycogen (starch) synthase activity
DOO79_06720	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DOO79_06725	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DOO79_06750	COG0702	epimerase
DOO79_06755	COG1028	Short-chain dehydrogenase reductase Sdr
DOO79_06790	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DOO79_06795	COG1028	Short-chain dehydrogenase reductase Sdr
DOO79_06810	COG0513	Belongs to the DEAD box helicase family
DOO79_06830	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DOO79_06845	COG3483	tryptophan 2,3-dioxygenase activity
DOO79_06850	COG3104	oligopeptide transport
DOO79_06875	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
DOO79_06895	COG1320	monovalent cation:proton antiporter activity
DOO79_06900	COG2212	antiporter activity
DOO79_06910	COG0651	ATP synthesis coupled electron transport
DOO79_06915	COG1006	Multisubunit Na H antiporter MnhC subunit
DOO79_06920	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DOO79_06920	COG2111	Na H antiporter
DOO79_06945	COG3179	chitinase
DOO79_06965	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DOO79_06970	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
DOO79_06985	COG0456	acetyltransferase
DOO79_06990	COG1597	lipid kinase activity
DOO79_07015	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DOO79_07020	COG0134	indole-3-glycerol-phosphate synthase activity
DOO79_07030	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DOO79_07035	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
DOO79_07045	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
DOO79_07055	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DOO79_07070	COG1051	belongs to the nudix hydrolase family
DOO79_07110	COG0316	Belongs to the HesB IscA family
DOO79_07130	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DOO79_07150	COG2814	Major facilitator Superfamily
DOO79_07160	COG2814	Major facilitator Superfamily
DOO79_07165	COG1289	transmembrane transporter activity
DOO79_07175	COG0151	Belongs to the GarS family
DOO79_07185	COG0138	bifunctional purine biosynthesis protein purh
DOO79_07190	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DOO79_07195	COG2267	carboxylic ester hydrolase activity
DOO79_07200	COG2453	phosphatase
DOO79_07200	COG0671	phosphoesterase, PA-phosphatase related
DOO79_07225	COG4589	Belongs to the CDS family
DOO79_07230	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
DOO79_07255	COG2264	protein methyltransferase activity
DOO79_07275	COG0439	Biotin carboxylase
DOO79_07285	COG0511	ligase activity, forming carbon-carbon bonds
DOO79_07290	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DOO79_07300	COG1324	tolerance protein
DOO79_07330	COG0300	oxidoreductase activity
DOO79_07340	COG2356	endonuclease I
DOO79_07350	COG0459	protein refolding
DOO79_07365	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DOO79_07380	COG3386	PFAM SMP-30 Gluconolaconase
DOO79_07395	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DOO79_07415	COG0778	Nitroreductase
DOO79_07420	COG2353	YceI-like domain
DOO79_07450	COG3052	prosthetic group binding
DOO79_07485	COG1802	Transcriptional regulator
DOO79_07560	COG4221	oxidoreductase activity
DOO79_07575	COG4221	oxidoreductase activity
DOO79_07590	COG0435	Glutathione S-transferase
DOO79_07615	COG2409	Drug exporters of the RND superfamily
DOO79_07625	COG1506	peptidase
DOO79_07625	COG0823	Involved in the tonB-independent uptake of proteins
DOO79_07645	COG3706	GGDEF domain
DOO79_07670	COG0697	spore germination
DOO79_07685	COG1113	amino acid transport
DOO79_07705	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
DOO79_07755	COG5001	Diguanylate cyclase
DOO79_07765	COG0840	transmembrane signaling receptor activity
DOO79_07770	COG5297	Belongs to the glycosyl hydrolase family 6
DOO79_07770	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DOO79_07775	COG0659	secondary active sulfate transmembrane transporter activity
DOO79_07785	COG3706	GGDEF domain
DOO79_07805	COG2943	transferase activity, transferring hexosyl groups
DOO79_07815	COG3275	phosphorelay sensor kinase activity
DOO79_07825	COG0181	hydroxymethylbilane synthase activity
DOO79_07865	COG1505	serine-type exopeptidase activity
DOO79_07885	COG2832	Protein of unknown function (DUF454)
DOO79_07895	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DOO79_07905	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DOO79_07910	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DOO79_07915	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DOO79_07940	COG2226	methyltransferase
DOO79_07945	COG2199	diguanylate cyclase activity
DOO79_07950	COG0308	aminopeptidase N
DOO79_07985	COG1162	GTPase activity
DOO79_08010	COG2211	Major facilitator Superfamily
DOO79_08015	COG1609	Transcriptional regulator
DOO79_08020	COG1028	Short-chain dehydrogenase reductase Sdr
DOO79_08025	COG2851	Citrate transporter
DOO79_08045	COG0642	Histidine kinase
DOO79_08060	COG2197	response regulator
DOO79_08080	COG0667	Aldo Keto reductase
DOO79_08090	COG0583	DNA-binding transcription factor activity
DOO79_08120	COG1301	dicarboxylic acid transport
DOO79_08125	COG0281	malic enzyme
DOO79_08125	COG0280	phosphate acetyltransferase
DOO79_08150	COG1560	Kdo2-lipid A biosynthetic process
DOO79_08155	COG1519	Transferase
DOO79_08160	COG1538	Outer membrane efflux protein
DOO79_08165	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DOO79_08185	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DOO79_08190	COG0066	3-isopropylmalate dehydratase activity
DOO79_08195	COG0473	3-isopropylmalate dehydrogenase activity
DOO79_08200	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DOO79_08220	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DOO79_08230	COG0840	transmembrane signaling receptor activity
DOO79_08245	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DOO79_08250	COG3710	Transcriptional regulator
DOO79_08280	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DOO79_08290	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DOO79_08315	COG0563	adenylate kinase activity
DOO79_08320	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DOO79_08330	COG3781	membrane
DOO79_08335	COG0671	phosphoesterase, PA-phosphatase related
DOO79_08345	COG1028	Short-chain dehydrogenase reductase Sdr
DOO79_08355	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DOO79_08360	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DOO79_08390	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DOO79_08405	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DOO79_08420	COG0352	thiamine-phosphate diphosphorylase activity
DOO79_08425	COG1773	rubredoxin
DOO79_08430	COG2912	Transglutaminase-like superfamily
DOO79_08440	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DOO79_08450	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DOO79_08470	COG3079	Belongs to the UPF0149 family
DOO79_08475	COG0006	proline dipeptidase activity
DOO79_08485	COG0006	proline dipeptidase activity
DOO79_08500	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DOO79_08505	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DOO79_08515	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DOO79_08520	COG1561	YicC-like family, N-terminal region
DOO79_08525	COG0194	GDP metabolic process
DOO79_08535	COG1070	Carbohydrate kinase
DOO79_08540	COG1028	Short-chain dehydrogenase reductase Sdr
DOO79_08560	COG3659	wide pore channel activity
DOO79_08575	COG2390	Transcriptional regulator
DOO79_08580	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DOO79_08585	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DOO79_08595	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DOO79_08625	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DOO79_08655	COG0714	Associated with various cellular activities
DOO79_08675	COG2304	oxidoreductase activity
DOO79_08690	COG1301	dicarboxylic acid transport
DOO79_08695	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DOO79_08700	COG0596	Alpha beta hydrolase
DOO79_08705	COG4773	Receptor
DOO79_08715	COG0739	heme binding
DOO79_08725	COG1376	ErfK ybiS ycfS ynhG family protein
DOO79_08760	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
DOO79_08765	COG4149	molybdate abc transporter
DOO79_08770	COG0725	ABC transporter, periplasmic molybdate-binding protein
DOO79_08775	COG3453	Protein conserved in bacteria
DOO79_08775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DOO79_08785	COG3047	cAMP biosynthetic process
DOO79_08790	COG3047	cAMP biosynthetic process
DOO79_08805	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DOO79_08830	COG0126	phosphoglycerate kinase activity
DOO79_08840	COG0469	pyruvate kinase activity
DOO79_08850	COG3588	fructose-bisphosphate aldolase
DOO79_08855	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
DOO79_08890	COG0784	Response regulator, receiver
DOO79_08890	COG2205	protein histidine kinase activity
DOO79_08890	COG2198	Histidine kinase
DOO79_08910	COG0175	sulfate reduction
DOO79_08915	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DOO79_08920	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DOO79_08925	COG0175	sulfate reduction
DOO79_08930	COG2895	sulfate adenylyltransferase (ATP) activity
DOO79_08930	COG0529	Catalyzes the synthesis of activated sulfate
DOO79_08935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DOO79_08940	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DOO79_08990	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DOO79_09005	COG4948	Mandelate Racemase Muconate Lactonizing
DOO79_09010	COG3250	beta-galactosidase activity
DOO79_09020	COG1609	Transcriptional regulator
DOO79_09030	COG1970	mechanosensitive ion channel activity
DOO79_09055	COG3273	potassium ion transport
DOO79_09055	COG0471	metal ion transport
DOO79_09060	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DOO79_09070	COG2022	thiamine diphosphate biosynthetic process
DOO79_09115	COG0189	ligase activity
DOO79_09125	COG0745	RESPONSE REGULATOR receiver
DOO79_09130	COG5002	protein histidine kinase activity
DOO79_09240	COG2010	Cytochrome c
DOO79_09260	COG3284	Transcriptional regulator
DOO79_09265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DOO79_09270	COG1077	Cell shape determining protein MreB Mrl
DOO79_09275	COG1792	Involved in formation and maintenance of cell shape
DOO79_09290	COG0772	Belongs to the SEDS family
DOO79_09305	COG2951	lytic endotransglycosylase activity
DOO79_09310	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DOO79_09320	COG1686	Belongs to the peptidase S11 family
DOO79_09330	COG2921	Belongs to the UPF0250 family
DOO79_09335	COG0321	lipoyl(octanoyl) transferase activity
DOO79_09340	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DOO79_09355	COG0583	DNA-binding transcription factor activity
DOO79_09365	COG1056	cytidyltransferase-related domain
DOO79_09365	COG1051	belongs to the nudix hydrolase family
DOO79_09400	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
DOO79_09405	COG0673	inositol 2-dehydrogenase activity
DOO79_09410	COG2823	Periplasmic or secreted lipoprotein
DOO79_09415	COG4251	negative regulation of phosphorylation
DOO79_09420	COG0784	Response regulator, receiver
DOO79_09425	COG4191	Histidine kinase
DOO79_09430	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DOO79_09490	COG1459	type II secretion system
DOO79_09510	COG4795	General secretion pathway protein
DOO79_09540	COG3250	beta-galactosidase activity
DOO79_09555	COG2188	Transcriptional regulator
DOO79_09565	COG1609	Transcriptional regulator
DOO79_09570	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DOO79_09575	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DOO79_09585	COG0617	tRNA 3'-terminal CCA addition
DOO79_09590	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
DOO79_09595	COG1012	belongs to the aldehyde dehydrogenase family
DOO79_09600	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DOO79_09615	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DOO79_09630	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DOO79_09635	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DOO79_09655	COG2205	protein histidine kinase activity
DOO79_09660	COG0745	RESPONSE REGULATOR receiver
DOO79_09685	COG3791	Glutathione-dependent formaldehyde-activating
DOO79_09700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DOO79_09710	COG0697	spore germination
DOO79_09720	COG0488	(ABC) transporter
DOO79_09730	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DOO79_09735	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DOO79_09745	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DOO79_09745	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DOO79_09765	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DOO79_09770	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DOO79_09775	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DOO79_09800	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DOO79_09805	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DOO79_09810	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DOO79_09815	COG2205	protein histidine kinase activity
DOO79_09820	COG0745	RESPONSE REGULATOR receiver
DOO79_09850	COG0277	FAD linked oxidase domain protein
DOO79_09855	COG1988	membrane-bound metal-dependent
DOO79_09860	COG0792	nuclease activity
DOO79_09900	COG0275	rRNA processing
DOO79_09905	COG3116	cell division
DOO79_09915	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DOO79_09920	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DOO79_09925	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DOO79_09935	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DOO79_09940	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DOO79_09945	COG1181	Belongs to the D-alanine--D-alanine ligase family
DOO79_09950	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DOO79_09965	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
DOO79_09980	COG0653	protein targeting
DOO79_09985	COG0494	nUDIX hydrolase
DOO79_09995	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DOO79_10010	COG0604	alcohol dehydrogenase
DOO79_10010	COG3321	synthase
DOO79_10010	COG1028	Short-chain dehydrogenase reductase Sdr
DOO79_10040	COG0366	Alpha amylase catalytic
DOO79_10075	COG2226	methyltransferase
DOO79_10080	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DOO79_10090	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DOO79_10140	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DOO79_10150	COG4106	trans-aconitate 2-methyltransferase activity
DOO79_10155	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DOO79_10165	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DOO79_10170	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DOO79_10180	COG0667	Aldo Keto reductase
DOO79_10190	COG4771	TonB-dependent receptor
DOO79_10210	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DOO79_10215	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DOO79_10225	COG2175	clavaminate synthase activity
DOO79_10235	COG4181	ATPase activity
DOO79_10250	COG0642	Histidine kinase
DOO79_10270	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DOO79_10285	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DOO79_10290	COG2201	protein-glutamate methylesterase activity
DOO79_10295	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DOO79_10300	COG2200	EAL domain
DOO79_10300	COG2199	diguanylate cyclase activity
DOO79_10300	COG2202	Pas domain
DOO79_10305	COG0835	chemotaxis
DOO79_10310	COG0840	transmembrane signaling receptor activity
DOO79_10315	COG0643	Histidine kinase
DOO79_10315	COG2198	Histidine kinase
DOO79_10325	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DOO79_10335	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
DOO79_10345	COG2205	protein histidine kinase activity
DOO79_10350	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DOO79_10360	COG4452	Inner membrane protein CreD
DOO79_10385	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DOO79_10390	COG0735	belongs to the Fur family
DOO79_10405	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DOO79_10425	COG2207	Transcriptional regulator
DOO79_10435	COG0583	DNA-binding transcription factor activity
DOO79_10440	COG2814	Major facilitator Superfamily
DOO79_10525	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
DOO79_10575	COG5002	protein histidine kinase activity
DOO79_10575	COG5001	Diguanylate cyclase
DOO79_10580	COG1187	pseudouridine synthase activity
DOO79_10605	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DOO79_10615	COG0475	glutathione-regulated potassium exporter activity
DOO79_10620	COG5002	protein histidine kinase activity
DOO79_10620	COG5000	phosphorelay sensor kinase activity
DOO79_10625	COG0745	RESPONSE REGULATOR receiver
DOO79_10630	COG1538	Outer membrane efflux protein
DOO79_10660	COG1132	(ABC) transporter
DOO79_10705	COG2155	Conserved Protein
DOO79_10745	COG3118	belongs to the thioredoxin family
DOO79_10770	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DOO79_10785	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DOO79_10805	COG2968	Membrane
DOO79_10810	COG0424	maF-like protein
DOO79_10815	COG1530	ribonuclease E activity
DOO79_10820	COG3164	Protein of unknown function
DOO79_10830	COG0312	modulator of DNA gyrase
DOO79_10835	COG3028	Belongs to the UPF0307 family
DOO79_10840	COG0312	modulator of DNA gyrase
DOO79_10855	COG3318	Belongs to the UPF0149 family
DOO79_10855	COG3012	SEC-C Motif Domain Protein
DOO79_10885	COG0142	geranyltranstransferase activity
DOO79_10890	COG1722	exodeoxyribonuclease VII activity
DOO79_10895	COG0037	tRNA processing
DOO79_10905	COG1785	Belongs to the alkaline phosphatase family
DOO79_10910	COG1301	dicarboxylic acid transport
DOO79_10915	COG4106	trans-aconitate 2-methyltransferase activity
DOO79_10925	COG0791	NLP P60 protein
DOO79_10930	COG0791	NLP P60 protein
DOO79_10935	COG1047	Peptidyl-prolyl cis-trans
DOO79_10940	COG2311	Membrane
DOO79_10945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DOO79_10950	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DOO79_10975	COG3590	peptidase
DOO79_10985	COG3590	peptidase
DOO79_11045	COG3209	COG3209 Rhs family protein
DOO79_11095	COG3250	beta-galactosidase activity
DOO79_11100	COG3867	Arabinogalactan endo-beta-1,4-galactanase
DOO79_11120	COG1960	acyl-CoA dehydrogenase activity
DOO79_11125	COG1024	Enoyl-CoA hydratase
DOO79_11160	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DOO79_11165	COG0481	GTPase activity
DOO79_11180	COG0571	ribonuclease III activity
DOO79_11185	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DOO79_11190	COG1381	Involved in DNA repair and RecF pathway recombination
DOO79_11200	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DOO79_11210	COG2954	triphosphatase activity
DOO79_11215	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DOO79_11220	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
DOO79_11225	COG3046	protein related to deoxyribodipyrimidine photolyase
DOO79_11230	COG1472	Belongs to the glycosyl hydrolase 3 family
DOO79_11240	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DOO79_11250	COG1278	Cold shock
DOO79_11265	COG1201	RNA secondary structure unwinding
DOO79_11270	COG1793	dna ligase
DOO79_11280	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DOO79_11280	COG1793	dna ligase
DOO79_11310	COG0183	Belongs to the thiolase family
DOO79_11335	COG1451	nucleotide metabolic process
DOO79_11340	COG5487	UPF0391 membrane protein
DOO79_11350	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DOO79_11370	COG1047	Peptidyl-prolyl cis-trans
DOO79_11380	COG2824	Alkylphosphonate utilization operon protein PhnA
DOO79_11395	COG2814	Major facilitator Superfamily
DOO79_11425	COG0392	lysyltransferase activity
DOO79_11425	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DOO79_11435	COG0251	oxidation-reduction process
DOO79_11440	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DOO79_11455	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DOO79_11480	COG1595	DNA-templated transcription, initiation
DOO79_11500	COG2878	Part of a membrane complex involved in electron transport
DOO79_11510	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DOO79_11510	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DOO79_11525	COG1131	(ABC) transporter
DOO79_11530	COG0346	lactoylglutathione lyase activity
DOO79_11535	COG0833	amino acid
DOO79_11540	COG2040	homocysteine
DOO79_11550	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DOO79_11570	COG1695	Transcriptional regulator
DOO79_11605	COG0825	malonyl-CoA metabolic process
DOO79_11615	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DOO79_11620	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DOO79_11625	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DOO79_11630	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DOO79_11635	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DOO79_11650	COG0750	zinc metalloprotease
DOO79_11655	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DOO79_11660	COG0575	Belongs to the CDS family
DOO79_11665	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DOO79_11670	COG0233	cytoplasmic translational termination
DOO79_11675	COG0528	UMP kinase activity
DOO79_11685	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DOO79_11690	COG0052	Belongs to the universal ribosomal protein uS2 family
DOO79_11730	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
DOO79_11740	COG1393	Belongs to the ArsC family
DOO79_11745	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DOO79_11750	COG0367	asparagine synthase
DOO79_11760	COG4774	siderophore transport
DOO79_11805	COG1566	PFAM secretion protein HlyD family protein
DOO79_11810	COG2814	Major facilitator Superfamily
DOO79_11835	COG3104	oligopeptide transport
DOO79_11865	COG0339	signal peptide processing
DOO79_11875	COG0386	Belongs to the glutathione peroxidase family
DOO79_11935	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DOO79_11940	COG0084	hydrolase, TatD family'
DOO79_11955	COG1960	acyl-CoA dehydrogenase activity
DOO79_11975	COG0367	asparagine synthase
DOO79_11985	COG0305	Participates in initiation and elongation during chromosome replication
DOO79_11990	COG0415	Belongs to the DNA photolyase family
DOO79_12010	COG0583	DNA-binding transcription factor activity
DOO79_12045	COG3706	GGDEF domain
DOO79_12055	COG3706	GGDEF domain
DOO79_12085	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DOO79_12100	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DOO79_12110	COG0497	DNA recombination
DOO79_12115	COG1420	regulation of RNA biosynthetic process
DOO79_12120	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DOO79_12125	COG0443	Heat shock 70 kDa protein
DOO79_12130	COG0484	heat shock protein binding
DOO79_12170	COG0583	DNA-binding transcription factor activity
DOO79_12175	COG1132	(ABC) transporter
DOO79_12210	COG2850	peptidyl-arginine hydroxylation
DOO79_12230	COG1253	flavin adenine dinucleotide binding
DOO79_12260	COG1131	(ABC) transporter
DOO79_12265	COG1725	Transcriptional regulator
DOO79_12275	COG0386	Belongs to the glutathione peroxidase family
DOO79_12290	COG2900	Belongs to the SlyX family
DOO79_12315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DOO79_12340	COG0646	methionine synthase
DOO79_12340	COG1410	methionine synthase
DOO79_12345	COG2226	methyltransferase
DOO79_12350	COG1960	acyl-CoA dehydrogenase activity
DOO79_12355	COG1960	acyl-CoA dehydrogenase activity
DOO79_12375	COG0557	exoribonuclease II activity
DOO79_12385	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DOO79_12390	COG3706	GGDEF domain
DOO79_12395	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DOO79_12405	COG0704	Plays a role in the regulation of phosphate uptake
DOO79_12410	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DOO79_12415	COG0581	inorganic phosphate transmembrane transporter activity
DOO79_12420	COG0573	inorganic phosphate transmembrane transporter activity
DOO79_12425	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DOO79_12450	COG0659	secondary active sulfate transmembrane transporter activity
DOO79_12455	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DOO79_12465	COG1024	Enoyl-CoA hydratase
DOO79_12475	COG0494	nUDIX hydrolase
DOO79_12525	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DOO79_12550	COG2925	Exonuclease
DOO79_12560	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DOO79_12565	COG3844	kynureninase activity
DOO79_12575	COG0662	Cupin 2, conserved barrel domain protein
DOO79_12580	COG0288	reversible hydration of carbon dioxide
DOO79_12645	COG2808	Putative FMN-binding domain
DOO79_12665	COG0017	Asparaginyl-tRNA synthetase
DOO79_12675	COG0316	Belongs to the HesB IscA family
DOO79_12680	COG0360	Binds together with S18 to 16S ribosomal RNA
DOO79_12685	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DOO79_12690	COG0359	binds to the 23S rRNA
DOO79_12700	COG3115	cell septum assembly
DOO79_12710	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DOO79_12715	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DOO79_12720	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
DOO79_12735	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DOO79_12745	COG4993	Dehydrogenase
DOO79_12755	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DOO79_12765	COG2986	histidine ammonia-lyase
DOO79_12770	COG1228	amidohydrolase
DOO79_12810	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
DOO79_12815	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DOO79_12820	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DOO79_12825	COG0077	Prephenate dehydratase
DOO79_12825	COG1605	Chorismate mutase
DOO79_12830	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DOO79_12845	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DOO79_12850	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DOO79_12855	COG0583	DNA-binding transcription factor activity
DOO79_12880	COG0840	transmembrane signaling receptor activity
DOO79_12915	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
DOO79_12920	COG0784	Response regulator, receiver
DOO79_12920	COG4191	Histidine kinase
DOO79_12935	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DOO79_12945	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
DOO79_12955	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DOO79_12970	COG1595	DNA-templated transcription, initiation
DOO79_13025	COG2244	polysaccharide biosynthetic process
DOO79_13060	COG2264	protein methyltransferase activity
DOO79_13085	COG1136	(ABC) transporter
DOO79_13090	COG1132	(ABC) transporter
DOO79_13095	COG0477	Major facilitator Superfamily
DOO79_13100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DOO79_13115	COG1253	flavin adenine dinucleotide binding
DOO79_13130	COG0306	phosphate transporter
DOO79_13160	COG0504	CTP synthase activity
DOO79_13165	COG2877	3-deoxy-8-phosphooctulonate synthase activity
DOO79_13175	COG0148	phosphopyruvate hydratase activity
DOO79_13180	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DOO79_13185	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DOO79_13190	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DOO79_13195	COG0585	pseudouridine synthase activity
DOO79_13200	COG2840	Smr protein MutS2
DOO79_13205	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
DOO79_13210	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DOO79_13215	COG1238	metal cluster binding
DOO79_13230	COG1534	Rna-binding protein
DOO79_13235	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
DOO79_13245	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DOO79_13250	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DOO79_13260	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DOO79_13265	COG1546	Belongs to the CinA family
DOO79_13275	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DOO79_13280	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DOO79_13290	COG2137	regulation of response to DNA damage stimulus
DOO79_13295	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DOO79_13300	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
DOO79_13320	COG1741	Belongs to the pirin family
DOO79_13325	COG0583	DNA-binding transcription factor activity
DOO79_13350	COG0351	phosphomethylpyrimidine kinase
DOO79_13365	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DOO79_13370	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DOO79_13385	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DOO79_13395	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DOO79_13400	COG3734	2-keto-3-deoxy-galactonokinase
DOO79_13410	COG4948	Mandelate Racemase Muconate Lactonizing
DOO79_13415	COG0800	Aldolase
DOO79_13455	COG1501	Belongs to the glycosyl hydrolase 31 family
DOO79_13465	COG1070	Carbohydrate kinase
DOO79_13470	COG2115	Belongs to the xylose isomerase family
DOO79_13475	COG0477	Major facilitator Superfamily
DOO79_13495	COG0860	N-Acetylmuramoyl-L-alanine amidase
DOO79_13500	COG1469	GTP cyclohydrolase I activity
DOO79_13520	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DOO79_13525	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DOO79_13530	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DOO79_13535	COG0166	Belongs to the GPI family
DOO79_13560	COG1472	Belongs to the glycosyl hydrolase 3 family
DOO79_13575	COG3706	GGDEF domain
DOO79_13575	COG2203	Gaf domain
DOO79_13575	COG5001	Diguanylate cyclase
DOO79_13575	COG4251	negative regulation of phosphorylation
DOO79_13585	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DOO79_13590	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
DOO79_13605	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DOO79_13610	COG0671	phosphoesterase, PA-phosphatase related
DOO79_13640	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DOO79_13645	COG0167	dihydroorotate dehydrogenase activity
DOO79_13665	COG1012	belongs to the aldehyde dehydrogenase family
DOO79_13690	COG0326	Molecular chaperone. Has ATPase activity
DOO79_13695	COG0742	ribosomal rna small subunit methyltransferase
DOO79_13700	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DOO79_13715	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DOO79_13720	COG0405	Gamma-glutamyltransferase
DOO79_13725	COG3291	Pkd domain containing protein
DOO79_13730	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DOO79_13770	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DOO79_13775	COG0343	queuine tRNA-ribosyltransferase activity
DOO79_13780	COG1862	Preprotein translocase
DOO79_13790	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DOO79_13830	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DOO79_13830	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DOO79_13835	COG1105	Belongs to the carbohydrate kinase PfkB family
DOO79_13840	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DOO79_13840	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DOO79_13845	COG1609	Transcriptional regulator
DOO79_13855	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DOO79_13860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DOO79_13870	COG2902	Dehydrogenase
DOO79_13905	COG1238	metal cluster binding
DOO79_13925	COG1028	Short-chain dehydrogenase reductase Sdr
DOO79_13960	COG1073	alpha beta
DOO79_13960	COG2226	methyltransferase
DOO79_14055	COG0316	Belongs to the HesB IscA family
DOO79_14055	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
DOO79_14060	COG2154	pterin-4-alpha-carbinolamine dehydratase
DOO79_14070	COG0428	transporter
DOO79_14075	COG3064	Membrane
DOO79_14085	COG1530	ribonuclease E activity
DOO79_14115	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
DOO79_14140	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DOO79_14220	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DOO79_14225	COG0322	excinuclease ABC activity
DOO79_14235	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DOO79_14240	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
DOO79_14245	COG1663	tetraacyldisaccharide 4'-kinase activity
DOO79_14250	COG1132	(ABC) transporter
DOO79_14260	COG0811	peptide transport
DOO79_14275	COG1136	(ABC) transporter
DOO79_14280	COG4591	ABC-type transport system involved in lipoprotein release permease component
DOO79_14290	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
DOO79_14310	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
DOO79_14335	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DOO79_14340	COG0837	glucose binding
DOO79_14345	COG0363	glucosamine-6-phosphate deaminase activity
DOO79_14350	COG0129	dihydroxy-acid dehydratase activity
DOO79_14355	COG0800	Aldolase
DOO79_14430	COG2205	protein histidine kinase activity
DOO79_14430	COG0784	Response regulator, receiver
DOO79_14435	COG2183	response to ionizing radiation
DOO79_14445	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DOO79_14445	COG0723	plastoquinol--plastocyanin reductase activity
DOO79_14460	COG3243	poly(R)-hydroxyalkanoic acid synthase
DOO79_14470	COG1183	phosphatidylcholine synthase activity
DOO79_14475	COG1028	Short-chain dehydrogenase reductase Sdr
DOO79_14490	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DOO79_14500	COG0668	transmembrane transport
DOO79_14520	COG4456	Virulence-associated protein
DOO79_14585	COG3012	SEC-C Motif Domain Protein
DOO79_14585	COG3318	Belongs to the UPF0149 family
DOO79_14605	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DOO79_14635	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
DOO79_14650	COG1914	H( )-stimulated, divalent metal cation uptake system
DOO79_14670	COG2814	Major facilitator Superfamily
DOO79_14695	COG1335	isochorismatase
DOO79_14710	COG2197	response regulator
DOO79_14730	COG0583	DNA-binding transcription factor activity
DOO79_14735	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DOO79_14740	COG3002	Belongs to the UPF0753 family
DOO79_14745	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DOO79_14745	COG0519	Catalyzes the synthesis of GMP from XMP
DOO79_14755	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DOO79_14765	COG0475	glutathione-regulated potassium exporter activity
DOO79_14765	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DOO79_14775	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DOO79_14785	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DOO79_14790	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
DOO79_14800	COG0776	regulation of translation
DOO79_14805	COG0539	negative regulation of cytoplasmic translation
DOO79_14810	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DOO79_14830	COG2957	Belongs to the agmatine deiminase family
DOO79_14835	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DOO79_14860	COG0395	ABC-type sugar transport system, permease component
DOO79_14865	COG1175	transmembrane transport
DOO79_14895	COG2350	Protein conserved in bacteria
DOO79_14900	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DOO79_14905	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DOO79_14910	COG1187	pseudouridine synthase activity
DOO79_14930	COG0436	Aminotransferase
DOO79_14935	COG4133	protoheme IX ABC transporter activity
DOO79_14955	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
DOO79_14960	COG1138	Cytochrome C-type biogenesis protein
DOO79_14980	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DOO79_14985	COG1278	Cold shock
DOO79_14990	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DOO79_14995	COG4988	ABC transporter
DOO79_15005	COG1294	oxidase, subunit
DOO79_15015	COG3344	reverse transcriptase
DOO79_15040	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DOO79_15045	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DOO79_15055	COG0165	Argininosuccinate lyase
DOO79_15060	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DOO79_15070	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DOO79_15075	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DOO79_15085	COG0137	argininosuccinate synthase activity
DOO79_15090	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DOO79_15100	COG0215	cysteine-tRNA ligase activity
DOO79_15105	COG2166	iron-sulfur cluster assembly
DOO79_15120	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DOO79_15125	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DOO79_15155	COG4302	ethanolamine ammonia-lyase activity
DOO79_15225	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DOO79_15230	COG0402	S-adenosylhomocysteine deaminase activity
DOO79_15240	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DOO79_15245	COG1509	lysine 2,3-aminomutase activity
DOO79_15250	COG3300	MHYT domain
DOO79_15250	COG5001	Diguanylate cyclase
DOO79_15265	COG0483	inositol monophosphate 1-phosphatase activity
DOO79_15270	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DOO79_15295	COG0513	Belongs to the DEAD box helicase family
DOO79_15300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DOO79_15305	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
DOO79_15315	COG0625	glutathione transferase activity
DOO79_15325	COG4681	YaeQ
DOO79_15330	COG2081	HI0933 family
DOO79_15375	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DOO79_15380	COG1028	Short-chain dehydrogenase reductase Sdr
DOO79_15405	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DOO79_15410	COG0860	N-Acetylmuramoyl-L-alanine amidase
DOO79_15415	COG0802	atpase or kinase
DOO79_15420	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DOO79_15420	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DOO79_15425	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DOO79_15430	COG1570	exodeoxyribonuclease VII activity
DOO79_15445	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DOO79_15485	COG0835	chemotaxis
DOO79_15490	COG0840	transmembrane signaling receptor activity
DOO79_15495	COG2094	Belongs to the DNA glycosylase MPG family
DOO79_15500	COG1201	RNA secondary structure unwinding
DOO79_15520	COG2969	positive regulation of protein catabolic process
DOO79_15525	COG0625	glutathione transferase activity
DOO79_15530	COG2857	Cytochrome c1
DOO79_15535	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DOO79_15550	COG0741	lytic transglycosylase activity
DOO79_15565	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DOO79_15570	COG1702	phosphate starvation-inducible protein PhoH
DOO79_15580	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DOO79_15590	COG4535	Mg2 and Co2 transporter CorC
DOO79_15605	COG1012	belongs to the aldehyde dehydrogenase family
DOO79_15610	COG1177	transmembrane transport
DOO79_15615	COG1176	ABC-type spermidine putrescine transport system, permease component I
DOO79_15620	COG3842	ATPase activity
DOO79_15640	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DOO79_15655	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DOO79_15660	COG0174	glutamine synthetase
DOO79_15665	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DOO79_15675	COG2703	oxygen carrier activity
DOO79_15680	COG0477	Major facilitator Superfamily
DOO79_15690	COG0243	molybdopterin cofactor binding
DOO79_15695	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DOO79_15700	COG2223	nitrite transmembrane transporter activity
DOO79_15725	COG2733	membrane
DOO79_15730	COG0784	Response regulator, receiver
DOO79_15730	COG5002	protein histidine kinase activity
DOO79_15730	COG2205	protein histidine kinase activity
DOO79_15740	COG0477	Major facilitator Superfamily
DOO79_15770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DOO79_15790	COG4566	intracellular signal transduction
DOO79_15820	COG3685	Protein conserved in bacteria
DOO79_15860	COG1648	precorrin-2 dehydrogenase activity
DOO79_15860	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DOO79_15870	COG0746	molybdenum cofactor guanylyltransferase activity
DOO79_15885	COG0708	Exodeoxyribonuclease III
DOO79_15925	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DOO79_15935	COG0303	'Molybdopterin
DOO79_15940	COG1160	GTP binding
DOO79_15945	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DOO79_15955	COG1426	Protein conserved in bacteria
DOO79_15965	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DOO79_15980	COG1250	3-hydroxyacyl-CoA dehydrogenase
DOO79_15980	COG1024	Enoyl-CoA hydratase
DOO79_15985	COG0183	Belongs to the thiolase family
DOO79_15995	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DOO79_16000	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DOO79_16010	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DOO79_16020	COG1674	ftsk spoiiie
DOO79_16025	COG0492	ferredoxin-NADP+ reductase activity
DOO79_16045	COG0542	response to heat
DOO79_16060	COG0482	sulfurtransferase activity
DOO79_16065	COG2915	High frequency lysogenization protein hflD homolog
DOO79_16095	COG5002	protein histidine kinase activity
DOO79_16115	COG0784	Response regulator, receiver
DOO79_16115	COG0835	chemotaxis
DOO79_16125	COG1558	bacterial-type flagellum-dependent cell motility
DOO79_16130	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DOO79_16140	COG4787	bacterial-type flagellum-dependent cell motility
DOO79_16155	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
DOO79_16160	COG1706	bacterial-type flagellum-dependent cell motility
DOO79_16165	COG1705	Flagellar rod assembly protein muramidase FlgJ
DOO79_16165	COG3951	Flagellar rod assembly protein muramidase FlgJ
DOO79_16175	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DOO79_16180	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DOO79_16185	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
DOO79_16215	COG2201	protein-glutamate methylesterase activity
DOO79_16260	COG1028	Short-chain dehydrogenase reductase Sdr
DOO79_16265	COG1028	Short-chain dehydrogenase reductase Sdr
DOO79_16310	COG1677	Flagellar hook-basal body complex protein FliE
DOO79_16360	COG3190	flagellar
DOO79_16380	COG1684	flagellar biosynthetic protein fliR
DOO79_16385	COG3300	MHYT domain
DOO79_16385	COG5001	Diguanylate cyclase
DOO79_16410	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DOO79_16440	COG0784	Response regulator, receiver
DOO79_16440	COG0643	Histidine kinase
DOO79_16440	COG2198	Histidine kinase
DOO79_16455	COG0641	radical SAM
DOO79_16490	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DOO79_16495	COG1360	Flagellar Motor Protein
DOO79_16515	COG0745	RESPONSE REGULATOR receiver
DOO79_16520	COG2198	Histidine kinase
DOO79_16520	COG0643	Histidine kinase
DOO79_16525	COG0840	transmembrane signaling receptor activity
DOO79_16540	COG0840	transmembrane signaling receptor activity
DOO79_16555	COG0840	transmembrane signaling receptor activity
DOO79_16560	COG0840	transmembrane signaling receptor activity
DOO79_16570	COG0840	transmembrane signaling receptor activity
DOO79_16575	COG0840	transmembrane signaling receptor activity
DOO79_16585	COG0840	transmembrane signaling receptor activity
DOO79_16590	COG0840	transmembrane signaling receptor activity
DOO79_16595	COG0840	transmembrane signaling receptor activity
DOO79_16600	COG0840	transmembrane signaling receptor activity
DOO79_16605	COG0840	transmembrane signaling receptor activity
DOO79_16615	COG0835	chemotaxis
DOO79_16625	COG0840	transmembrane signaling receptor activity
DOO79_16635	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
DOO79_16640	COG2201	protein-glutamate methylesterase activity
DOO79_16650	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DOO79_16680	COG0318	PFAM AMP-dependent synthetase and ligase
DOO79_16715	COG1024	Enoyl-CoA hydratase
DOO79_16720	COG2205	protein histidine kinase activity
DOO79_16720	COG2198	Histidine kinase
DOO79_16720	COG0784	Response regulator, receiver
DOO79_16730	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DOO79_16740	COG3279	Response regulator of the LytR AlgR family
DOO79_16790	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DOO79_16800	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DOO79_16805	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DOO79_16815	COG0505	Belongs to the CarA family
DOO79_16820	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DOO79_16825	COG2258	MOSC domain
DOO79_16875	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DOO79_16895	COG0277	FAD linked oxidase domain protein
DOO79_16900	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DOO79_16910	COG0531	amino acid
DOO79_16920	COG2188	Transcriptional regulator
DOO79_16985	COG0531	amino acid
DOO79_16990	COG0235	Class ii aldolase
DOO79_16995	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
DOO79_17000	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
DOO79_17015	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DOO79_17015	COG0140	phosphoribosyl-ATP diphosphatase activity
DOO79_17020	COG0107	imidazoleglycerol-phosphate synthase activity
DOO79_17025	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DOO79_17030	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DOO79_17035	COG0131	Imidazoleglycerol-phosphate dehydratase
DOO79_17035	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DOO79_17040	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DOO79_17045	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DOO79_17050	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DOO79_17060	COG0124	histidyl-tRNA synthetase
DOO79_17065	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DOO79_17160	COG0726	polysaccharide deacetylase
DOO79_17160	COG1649	PFAM Uncharacterised BCR, COG1649
DOO79_17305	COG0531	amino acid
DOO79_17325	COG0006	proline dipeptidase activity
DOO79_17335	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DOO79_17350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DOO79_17355	COG3938	Belongs to the proline racemase family
DOO79_17365	COG0552	protein localization to endoplasmic reticulum
DOO79_17375	COG1194	a g-specific adenine glycosylase
DOO79_17380	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
DOO79_17385	COG0784	Response regulator, receiver
DOO79_17385	COG4191	Histidine kinase
DOO79_17430	COG3040	lipid binding
DOO79_17445	COG1960	acyl-CoA dehydrogenase activity
DOO79_17455	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DOO79_17475	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DOO79_17480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DOO79_17485	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DOO79_17510	COG0438	transferase activity, transferring glycosyl groups
DOO79_17520	COG0438	transferase activity, transferring glycosyl groups
DOO79_17525	COG0438	transferase activity, transferring glycosyl groups
DOO79_17575	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DOO79_17575	COG0072	phenylalanine-tRNA ligase activity
DOO79_17580	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DOO79_17595	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DOO79_17600	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DOO79_17650	COG2948	multi-organism process
DOO79_17670	COG3505	Type IV secretory pathway VirD4
DOO79_17685	COG0556	nucleotide-excision repair
DOO79_17740	COG1611	Belongs to the LOG family
DOO79_17755	COG2095	MarC family integral membrane protein
DOO79_17765	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DOO79_17800	COG1185	polyribonucleotide nucleotidyltransferase activity
DOO79_17805	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DOO79_17810	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DOO79_17815	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DOO79_17820	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DOO79_17825	COG0195	Participates in both transcription termination and antitermination
DOO79_17830	COG0779	Required for maturation of 30S ribosomal subunits
DOO79_17840	COG1007	ATP synthesis coupled electron transport
DOO79_17860	COG0839	Belongs to the complex I subunit 6 family
DOO79_17865	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DOO79_17870	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DOO79_17880	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DOO79_17885	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
DOO79_17890	COG0649	NAD binding
DOO79_17895	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DOO79_17900	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DOO79_17905	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DOO79_17920	COG0149	triose-phosphate isomerase activity
DOO79_17925	COG0300	oxidoreductase activity
DOO79_17955	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DOO79_17960	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DOO79_17965	COG0159	tryptophan synthase activity
DOO79_17975	COG0133	tryptophan synthase activity
DOO79_17985	COG0135	phosphoribosylanthranilate isomerase activity
DOO79_17990	COG0101	tRNA pseudouridine synthase activity
DOO79_18010	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DOO79_18015	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DOO79_18020	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DOO79_18025	COG2890	protein-(glutamine-N5) methyltransferase activity
DOO79_18035	COG0688	phosphatidylethanolamine metabolic process
DOO79_18050	COG0433	COG0433 Predicted ATPase
DOO79_18055	COG0494	nUDIX hydrolase
DOO79_18075	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DOO79_18080	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DOO79_18095	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DOO79_18125	COG4695	Portal protein
DOO79_18170	COG3179	chitinase
DOO79_18365	COG0717	Belongs to the dCTP deaminase family
DOO79_18375	COG0489	protein tyrosine kinase activity
DOO79_18400	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DOO79_18410	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
DOO79_18430	COG0534	Mate efflux family protein
DOO79_18435	COG0335	large ribosomal subunit rRNA binding
DOO79_18440	COG0336	Belongs to the RNA methyltransferase TrmD family
DOO79_18445	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DOO79_18450	COG0228	four-way junction DNA binding
DOO79_18455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DOO79_18465	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DOO79_18470	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DOO79_18510	COG3437	response regulator, receiver
DOO79_18510	COG2205	protein histidine kinase activity
DOO79_18510	COG3850	Histidine kinase
DOO79_18510	COG4999	Histidine kinase
DOO79_18515	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DOO79_18525	COG2205	protein histidine kinase activity
DOO79_18530	COG5507	3-demethylubiquinone-9 3-methyltransferase
DOO79_18540	COG4771	TonB-dependent receptor
DOO79_18565	COG2172	sigma factor antagonist activity
DOO79_18570	COG1366	Belongs to the anti-sigma-factor antagonist family
DOO79_18575	COG1366	Belongs to the anti-sigma-factor antagonist family
DOO79_18585	COG0326	Molecular chaperone. Has ATPase activity
DOO79_18590	COG2207	Transcriptional regulator
DOO79_18600	COG3152	Membrane
DOO79_18615	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DOO79_18620	COG1845	cytochrome c oxidase, subunit III
DOO79_18625	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DOO79_18640	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DOO79_18645	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DOO79_18650	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DOO79_18655	COG0196	riboflavin kinase activity
DOO79_18665	COG0268	Binds directly to 16S ribosomal RNA
DOO79_18670	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DOO79_18675	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DOO79_18680	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DOO79_18685	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DOO79_18690	COG0824	Thioesterase
DOO79_18740	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
DOO79_18750	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DOO79_18780	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
DOO79_18795	COG2197	response regulator
DOO79_18800	COG4585	Histidine kinase
DOO79_18815	COG0850	regulation of cytokinetic process
DOO79_18820	COG2894	cell division
DOO79_18825	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
DOO79_18835	COG0642	Histidine kinase
DOO79_18840	COG0745	RESPONSE REGULATOR receiver
DOO79_18855	COG2194	sulfuric ester hydrolase activity
DOO79_18870	COG2814	Major facilitator Superfamily
DOO79_18875	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DOO79_18875	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DOO79_18885	COG0656	L-ascorbic acid biosynthetic process
DOO79_18890	COG0753	catalase activity
DOO79_18915	COG1917	Cupin 2, conserved barrel domain protein
DOO79_18915	COG2207	Transcriptional regulator
DOO79_18975	COG0492	ferredoxin-NADP+ reductase activity
DOO79_18985	COG1028	Short-chain dehydrogenase reductase Sdr
DOO79_18990	COG3537	Alpha-1,2-mannosidase
DOO79_19000	COG1028	Short-chain dehydrogenase reductase Sdr
DOO79_19005	COG3387	PFAM Glycoside hydrolase 15-related
DOO79_19015	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DOO79_19055	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
DOO79_19080	COG0732	type I restriction modification DNA specificity domain
DOO79_19110	COG1309	transcriptional regulator
DOO79_19115	COG1028	Short-chain dehydrogenase reductase Sdr
DOO79_19120	COG0308	aminopeptidase N
DOO79_19125	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DOO79_19135	COG0330	HflC and HflK could
DOO79_19140	COG0330	HflC and HflK could
DOO79_19160	COG0678	peroxiredoxin activity
DOO79_19170	COG4953	penicillin-binding protein 1C
DOO79_19190	COG2373	Large extracellular alpha-helical protein
DOO79_19225	COG3609	addiction module antidote protein, CC2985 family
DOO79_19245	COG3829	transcription factor binding
DOO79_19270	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DOO79_19275	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DOO79_19290	COG1028	Short-chain dehydrogenase reductase Sdr
DOO79_19305	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DOO79_19310	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DOO79_19315	COG1399	metal-binding, possibly nucleic acid-binding protein
DOO79_19320	COG0424	maF-like protein
DOO79_19350	COG0714	Associated with various cellular activities
DOO79_19370	COG0537	adenosine 5'-monophosphoramidase activity
DOO79_19375	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DOO79_19380	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DOO79_19400	COG0314	molybdopterin synthase activity
DOO79_19405	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DOO79_19410	COG0315	cyclic pyranopterin monophosphate synthase activity
DOO79_19415	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DOO79_19420	COG1234	tRNA 3'-trailer cleavage
DOO79_19425	COG3642	lipopolysaccharide core region biosynthetic process
DOO79_19430	COG0859	PFAM glycosyl transferase family 9
DOO79_19445	COG0631	protein serine/threonine phosphatase activity
DOO79_19450	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DOO79_19455	COG0328	RNA-DNA hybrid ribonuclease activity
DOO79_19465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DOO79_19475	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DOO79_19500	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DOO79_19510	COG0544	peptidyl-prolyl cis-trans isomerase activity
DOO79_19520	COG3852	Histidine kinase
DOO79_19550	COG0473	3-isopropylmalate dehydrogenase activity
DOO79_19565	COG4783	chaperone-mediated protein folding
DOO79_19580	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DOO79_19590	COG0438	transferase activity, transferring glycosyl groups
DOO79_19595	COG0671	phosphoesterase, PA-phosphatase related
DOO79_19600	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DOO79_19620	COG2833	Protein of unknown function (DUF455)
DOO79_19640	COG0285	dihydrofolate synthase activity
DOO79_19650	COG0406	alpha-ribazole phosphatase activity
DOO79_19685	COG1063	alcohol dehydrogenase
DOO79_19695	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DOO79_19700	COG4208	sulfate ABC transporter
DOO79_19705	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DOO79_19710	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DOO79_19715	COG0156	8-amino-7-oxononanoate synthase activity
DOO79_19750	COG0446	pyridine nucleotide-disulphide oxidoreductase
DOO79_19750	COG1902	pentaerythritol trinitrate reductase activity
DOO79_19770	COG0625	glutathione transferase activity
DOO79_19780	COG0039	L-malate dehydrogenase activity
DOO79_19785	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DOO79_19800	COG0154	amidase activity
DOO79_19810	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
DOO79_19830	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
DOO79_19835	COG0203	ribosomal protein L17
DOO79_19860	COG0201	protein transport
DOO79_19865	COG0200	Binds to the 23S rRNA
DOO79_19870	COG1841	ribosomal large subunit assembly
DOO79_19880	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DOO79_19885	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DOO79_19890	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DOO79_19900	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DOO79_19905	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DOO79_19915	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DOO79_19920	COG0255	Belongs to the universal ribosomal protein uL29 family
DOO79_19925	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DOO79_19930	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DOO79_19940	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DOO79_19945	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DOO79_19950	COG0089	rRNA binding
DOO79_19955	COG0088	Forms part of the polypeptide exit tunnel
DOO79_19960	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DOO79_19965	COG0051	transcription antitermination factor activity, RNA binding
DOO79_19970	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DOO79_19975	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DOO79_19980	COG0049	tRNA binding
DOO79_19985	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DOO79_19990	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DOO79_19995	COG0085	RNA polymerase activity
DOO79_20000	COG0222	ribosome binding
DOO79_20005	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DOO79_20010	COG0081	regulation of translation
DOO79_20015	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DOO79_20020	COG0250	Participates in transcription elongation, termination and antitermination
DOO79_20035	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DOO79_20055	COG0012	GTP binding
DOO79_20060	COG0193	aminoacyl-tRNA hydrolase activity
DOO79_20065	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DOO79_20070	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DOO79_20080	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DOO79_20085	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
DOO79_20095	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DOO79_20100	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DOO79_20130	COG1254	Belongs to the acylphosphatase family
DOO79_20140	COG1295	ribonuclease BN
DOO79_20165	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DOO79_20170	COG1404	Belongs to the peptidase S8 family
DOO79_20180	COG1404	Belongs to the peptidase S8 family
DOO79_20190	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DOO79_20210	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
DOO79_20230	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
DOO79_20260	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DOO79_20260	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DOO79_20280	COG2890	protein-(glutamine-N5) methyltransferase activity
DOO79_20290	COG3634	alkyl hydroperoxide reductase activity
DOO79_20295	COG0583	DNA-binding transcription factor activity
DOO79_20305	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DOO79_20310	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DOO79_20320	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DOO79_20355	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DOO79_20365	COG0697	spore germination
DOO79_20385	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
DOO79_20400	COG3386	PFAM SMP-30 Gluconolaconase
DOO79_20420	COG1024	Enoyl-CoA hydratase
DOO79_20430	COG0318	PFAM AMP-dependent synthetase and ligase
DOO79_20435	COG0583	DNA-binding transcription factor activity
DOO79_20440	COG3384	dioxygenase
DOO79_20470	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DOO79_20475	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DOO79_20490	COG2096	Adenosyltransferase
DOO79_20495	COG0123	including yeast histone deacetylase and acetoin utilization protein
DOO79_20500	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
DOO79_20505	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DOO79_20510	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DOO79_20515	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DOO79_20520	COG2967	ApaG domain
DOO79_20525	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DOO79_20545	COG0747	negative chemotaxis
DOO79_20570	COG0431	NADPH-dependent FMN reductase
DOO79_20575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DOO79_20585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DOO79_20590	COG1116	anion transmembrane transporter activity
DOO79_20600	COG3829	transcription factor binding
DOO79_20615	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DOO79_20620	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DOO79_20650	COG0588	phosphoglycerate mutase activity
DOO79_20655	COG1515	deoxyribonuclease V activity
DOO79_20665	COG1741	Belongs to the pirin family
DOO79_20680	COG1741	Belongs to the pirin family
DOO79_20685	COG1966	Carbon starvation protein
DOO79_20690	COG2879	small protein
DOO79_20740	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DOO79_20745	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DOO79_20750	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
DOO79_20755	COG2080	2 iron, 2 sulfur cluster binding
DOO79_20760	COG0604	alcohol dehydrogenase
DOO79_20760	COG1028	Short-chain dehydrogenase reductase Sdr
DOO79_20760	COG3321	synthase
DOO79_20765	COG4251	negative regulation of phosphorylation
DOO79_20765	COG3706	GGDEF domain
DOO79_20765	COG2203	Gaf domain
DOO79_20765	COG5001	Diguanylate cyclase
DOO79_20770	COG0629	single-stranded DNA binding
DOO79_20775	COG0142	geranyltranstransferase activity
DOO79_20790	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DOO79_20805	COG0527	aspartate kinase activity
DOO79_20810	COG0384	phenazine biosynthesis protein PhzF
DOO79_20825	COG1764	response to oxidative stress
DOO79_20830	COG0540	Belongs to the ATCase OTCase family
DOO79_20835	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DOO79_20840	COG1678	Uncharacterized ACR, COG1678
DOO79_20850	COG0519	Catalyzes the synthesis of GMP from XMP
DOO79_20860	COG5297	Belongs to the glycosyl hydrolase family 6
DOO79_20875	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DOO79_20890	COG0739	heme binding
DOO79_20910	COG0693	protein deglycase activity
DOO79_20920	COG1959	2 iron, 2 sulfur cluster binding
DOO79_20925	COG0719	Fe-S assembly protein
DOO79_20930	COG0396	ATPase activity
DOO79_20935	COG0719	Fe-S assembly protein
DOO79_20940	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DOO79_20950	COG2146	nitrite reductase [NAD(P)H] activity
DOO79_20955	COG4774	siderophore transport
DOO79_20960	COG3128	pkhd-type hydroxylase
DOO79_20985	COG1477	protein flavinylation
DOO79_20990	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DOO79_21005	COG1555	photosystem II stabilization
DOO79_21020	COG3178	'Phosphotransferase
DOO79_21025	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DOO79_21035	COG0628	permease
DOO79_21045	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DOO79_21055	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DOO79_21075	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DOO79_21080	COG0271	Belongs to the BolA IbaG family
DOO79_21090	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DOO79_21100	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
DOO79_21105	COG1137	ATPase activity
DOO79_21120	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DOO79_21125	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DOO79_21130	COG1660	Displays ATPase and GTPase activities
DOO79_21140	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DOO79_21145	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DOO79_21155	COG2239	Acts as a magnesium transporter
DOO79_21170	COG1294	oxidase, subunit
DOO79_21175	COG1271	oxidase subunit
DOO79_21195	COG1113	amino acid transport
DOO79_21225	COG2197	response regulator
DOO79_21230	COG0531	amino acid
DOO79_21260	COG1234	tRNA 3'-trailer cleavage
DOO79_21325	COG2814	Major facilitator Superfamily
DOO79_21335	COG0754	glutathionylspermidine amidase activity
DOO79_21360	COG1842	Phage shock protein A
DOO79_21370	COG0259	pyridoxamine-phosphate oxidase activity
DOO79_21375	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DOO79_21380	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DOO79_21390	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DOO79_21395	COG0477	Major facilitator Superfamily
DOO79_21415	COG2205	protein histidine kinase activity
DOO79_21415	COG2198	Histidine kinase
DOO79_21415	COG0784	Response regulator, receiver
DOO79_21420	COG2353	YceI-like domain
DOO79_21440	COG1760	l-serine dehydratase
DOO79_21455	COG0527	aspartate kinase activity
DOO79_21455	COG0460	homoserine dehydrogenase
DOO79_21460	COG0626	cystathionine gamma-synthase activity
DOO79_21465	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DOO79_21470	COG0739	heme binding
DOO79_21475	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DOO79_21480	COG1272	protein, Hemolysin III
DOO79_21485	COG2982	Protein involved in outer membrane biogenesis
DOO79_21490	COG0517	IMP dehydrogenase activity
DOO79_21490	COG0516	GMP reductase activity
DOO79_21495	COG0463	Glycosyl transferase, family 2
DOO79_21500	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DOO79_21505	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DOO79_21515	COG4771	TonB-dependent receptor
DOO79_21530	COG1309	transcriptional regulator
DOO79_21540	COG1960	acyl-CoA dehydrogenase activity
DOO79_21570	COG0509	glycine decarboxylation via glycine cleavage system
DOO79_21575	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DOO79_21595	COG1742	UPF0060 membrane protein
DOO79_21600	COG3956	TIGRFAM MazG family protein
DOO79_21610	COG0494	nUDIX hydrolase
DOO79_21620	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DOO79_21625	COG0837	glucose binding
DOO79_21640	COG3858	chitin binding
DOO79_21640	COG1388	LysM domain
DOO79_21655	COG1472	Belongs to the glycosyl hydrolase 3 family
DOO79_21690	COG3537	Alpha-1,2-mannosidase
DOO79_21730	COG3142	Participates in the control of copper homeostasis
DOO79_21735	COG1446	asparaginase
DOO79_21765	COG2198	Histidine kinase
DOO79_21765	COG0643	Histidine kinase
DOO79_21765	COG0784	Response regulator, receiver
DOO79_21770	COG0840	transmembrane signaling receptor activity
DOO79_21775	COG0835	chemotaxis
DOO79_21790	COG0189	ligase activity
DOO79_21800	COG1397	ADP-ribosylglycohydrolase
DOO79_21810	COG1199	ATP-dependent helicase activity
DOO79_21820	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DOO79_21825	COG1215	transferase activity, transferring glycosyl groups
DOO79_21840	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DOO79_21850	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DOO79_21855	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
DOO79_21860	COG0535	radical SAM domain protein
DOO79_21865	COG0535	radical SAM domain protein
DOO79_21890	COG1643	Atp-dependent helicase
DOO79_21895	COG0783	Belongs to the Dps family
DOO79_21905	COG0514	ATP-dependent DNA helicase (RecQ)
DOO79_21940	COG0840	transmembrane signaling receptor activity
DOO79_21960	COG3920	Histidine kinase
DOO79_21965	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DOO79_21975	COG0602	queuosine metabolic process
DOO79_21985	COG2885	chlorophyll binding
DOO79_21990	COG0823	Involved in the tonB-independent uptake of proteins
DOO79_22000	COG0848	biopolymer transport protein
DOO79_22010	COG0824	Thioesterase
DOO79_22015	COG2255	four-way junction helicase activity
DOO79_22025	COG3158	transport of potassium into the cell
DOO79_22030	COG0632	four-way junction helicase activity
DOO79_22035	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DOO79_22040	COG0217	transcriptional regulatory protein
DOO79_22055	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DOO79_22070	COG0477	Major facilitator Superfamily
DOO79_22115	COG0488	(ABC) transporter
DOO79_22155	COG4651	solute:proton antiporter activity
DOO79_22155	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DOO79_22180	COG4772	TonB-dependent receptor
DOO79_22190	COG4264	IucA IucC family
DOO79_22205	COG0019	diaminopimelate decarboxylase activity
DOO79_22235	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DOO79_22245	COG1492	cobalamin metabolic process
DOO79_22275	COG4206	TonB-dependent receptor
DOO79_22280	COG0542	response to heat
DOO79_22285	COG1116	anion transmembrane transporter activity
DOO79_22290	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DOO79_22295	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DOO79_22300	COG0667	Aldo Keto reductase
DOO79_22305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DOO79_22310	COG4771	TonB-dependent receptor
DOO79_22320	COG2827	Endonuclease containing a URI domain
DOO79_22365	COG1877	trehalose-phosphatase activity
DOO79_22370	COG3387	PFAM Glycoside hydrolase 15-related
DOO79_22390	COG0840	transmembrane signaling receptor activity
DOO79_22395	COG3011	Protein conserved in bacteria
DOO79_22410	COG0564	pseudouridine synthase activity
DOO79_22415	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DOO79_22425	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DOO79_22425	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DOO79_22435	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DOO79_22440	COG0045	succinate-CoA ligase (ADP-forming) activity
DOO79_22485	COG1459	type II secretion system
DOO79_22490	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DOO79_22495	COG0237	dephospho-CoA kinase activity
DOO79_22515	COG0436	Aminotransferase
DOO79_22545	COG0726	polysaccharide deacetylase
DOO79_22550	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DOO79_22565	COG3964	amidohydrolase
DOO79_22570	COG0402	S-adenosylhomocysteine deaminase activity
DOO79_22605	COG1307	EDD domain protein, DegV family
DOO79_22610	COG0242	peptide deformylase activity
DOO79_22640	COG0457	Tetratricopeptide repeat
DOO79_22645	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
DOO79_22650	COG1215	transferase activity, transferring glycosyl groups
DOO79_22655	COG1215	transferase activity, transferring glycosyl groups
DOO79_22670	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DOO79_22735	COG2188	Transcriptional regulator
DOO79_22750	COG1450	Type ii and iii secretion system protein
DOO79_22765	COG3166	PFAM Fimbrial assembly family protein
DOO79_22770	COG3156	type II secretion system protein K
DOO79_22775	COG4795	General secretion pathway protein
DOO79_22780	COG2165	general secretion pathway protein
DOO79_22785	COG4970	Tfp pilus assembly protein FimT
DOO79_22790	COG2165	general secretion pathway protein
DOO79_22795	COG1459	type II secretion system
DOO79_22805	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DOO79_22810	COG1404	Belongs to the peptidase S8 family
DOO79_22815	COG5295	Hep Hag repeat protein
DOO79_22820	COG1404	Belongs to the peptidase S8 family
DOO79_22825	COG5295	Hep Hag repeat protein
DOO79_22830	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DOO79_22830	COG0047	phosphoribosylformylglycinamidine synthase activity
DOO79_22840	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DOO79_22850	COG4974	Belongs to the 'phage' integrase family
DOO79_22865	COG0795	lipopolysaccharide-transporting ATPase activity
DOO79_22875	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DOO79_22890	COG0525	valine-tRNA ligase activity
DOO79_22910	COG0741	lytic transglycosylase activity
DOO79_22930	COG1183	phosphatidylcholine synthase activity
DOO79_22940	COG0442	prolyl-tRNA aminoacylation
DOO79_22955	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DOO79_22960	COG1127	ABC transporter
DOO79_22965	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DOO79_22965	COG3218	ABC-type transport auxiliary lipoprotein component
DOO79_23000	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DOO79_23005	COG0662	Cupin 2, conserved barrel domain protein
DOO79_23005	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
DOO79_23035	COG2086	electron transfer activity
DOO79_23050	COG0546	phosphoglycolate phosphatase activity
DOO79_23050	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DOO79_23055	COG0277	FAD linked oxidase domain protein
DOO79_23070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DOO79_23200	COG4691	Plasmid stability protein
DOO79_23210	COG3318	Belongs to the UPF0149 family
DOO79_23210	COG3012	SEC-C Motif Domain Protein
DOO79_23265	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DOO79_23280	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DOO79_23395	COG1192	Involved in chromosome partitioning
DOO79_23535	COG3318	Belongs to the UPF0149 family
DOO79_23535	COG3012	SEC-C Motif Domain Protein
DOO79_23730	COG3704	protein secretion by the type IV secretion system
DOO79_23740	COG3504	Conjugal transfer protein
DOO79_23745	COG2948	multi-organism process
DOO79_23895	COG1192	Involved in chromosome partitioning
DOO79_23965	COG4691	Plasmid stability protein
DOO79_23970	COG1487	ribonuclease activity
DOO79_23980	COG3318	Belongs to the UPF0149 family
DOO79_23980	COG3012	SEC-C Motif Domain Protein