locus-tag	class	description
XcvCFBP7112P_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
XcvCFBP7112P_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
XcvCFBP7112P_00020	COG0187	DNA topoisomerase II activity
XcvCFBP7112P_00030	COG0501	Belongs to the peptidase M48B family
XcvCFBP7112P_00065	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
XcvCFBP7112P_00075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XcvCFBP7112P_00125	COG0793	Belongs to the peptidase S41A family
XcvCFBP7112P_00130	COG4942	peptidase
XcvCFBP7112P_00140	COG2234	aminopeptidase activity
XcvCFBP7112P_00150	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XcvCFBP7112P_00155	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XcvCFBP7112P_00165	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XcvCFBP7112P_00175	COG1064	alcohol dehydrogenase
XcvCFBP7112P_00190	COG0493	'glutamate synthase
XcvCFBP7112P_00195	COG0070	glutamate synthase
XcvCFBP7112P_00195	COG0069	glutamate synthase activity
XcvCFBP7112P_00195	COG0067	glutamate synthase
XcvCFBP7112P_00285	COG1111	helicase
XcvCFBP7112P_00285	COG1205	dead DEAH box helicase
XcvCFBP7112P_00310	COG0300	oxidoreductase activity
XcvCFBP7112P_00315	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7112P_00340	COG2249	NAD(P)H dehydrogenase (quinone) activity
XcvCFBP7112P_00410	COG3237	CsbD-like
XcvCFBP7112P_00460	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XcvCFBP7112P_00470	COG0477	Major facilitator Superfamily
XcvCFBP7112P_00505	COG4221	oxidoreductase activity
XcvCFBP7112P_00515	COG4221	oxidoreductase activity
XcvCFBP7112P_00520	COG1012	belongs to the aldehyde dehydrogenase family
XcvCFBP7112P_00550	COG0714	Associated with various cellular activities
XcvCFBP7112P_00585	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
XcvCFBP7112P_00595	COG4772	TonB-dependent receptor
XcvCFBP7112P_00610	COG1012	belongs to the aldehyde dehydrogenase family
XcvCFBP7112P_00635	COG1304	FMN binding
XcvCFBP7112P_00650	COG4585	Histidine kinase
XcvCFBP7112P_00655	COG2197	response regulator
XcvCFBP7112P_00680	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
XcvCFBP7112P_00790	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XcvCFBP7112P_00790	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
XcvCFBP7112P_00805	COG0366	Alpha amylase catalytic
XcvCFBP7112P_00815	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XcvCFBP7112P_00830	COG2272	Belongs to the type-B carboxylesterase lipase family
XcvCFBP7112P_00835	COG2755	lipolytic protein G-D-S-L family
XcvCFBP7112P_00835	COG0657	acetylesterase activity
XcvCFBP7112P_00845	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XcvCFBP7112P_00860	COG3507	Belongs to the glycosyl hydrolase 43 family
XcvCFBP7112P_00865	COG1609	Transcriptional regulator
XcvCFBP7112P_00880	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
XcvCFBP7112P_00885	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7112P_00895	COG2755	lipolytic protein G-D-S-L family
XcvCFBP7112P_00905	COG3186	Phenylalanine-4-hydroxylase
XcvCFBP7112P_00910	COG1522	sequence-specific DNA binding
XcvCFBP7112P_00920	COG1752	Esterase of the alpha-beta hydrolase superfamily
XcvCFBP7112P_00930	COG1119	ATPase activity
XcvCFBP7112P_00945	COG1125	glycine betaine transport
XcvCFBP7112P_00960	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XcvCFBP7112P_00995	COG0489	protein tyrosine kinase activity
XcvCFBP7112P_01000	COG2062	phosphohistidine phosphatase, SixA
XcvCFBP7112P_01010	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XcvCFBP7112P_01055	COG1968	undecaprenyl-diphosphatase activity
XcvCFBP7112P_01065	COG0174	glutamine synthetase
XcvCFBP7112P_01070	COG0347	Belongs to the P(II) protein family
XcvCFBP7112P_01075	COG0004	ammonium transporteR
XcvCFBP7112P_01080	COG3852	Histidine kinase
XcvCFBP7112P_01085	COG2204	response regulator
XcvCFBP7112P_01090	COG2032	superoxide dismutase activity
XcvCFBP7112P_01095	COG2032	superoxide dismutase activity
XcvCFBP7112P_01110	COG0183	Belongs to the thiolase family
XcvCFBP7112P_01145	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XcvCFBP7112P_01150	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
XcvCFBP7112P_01155	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
XcvCFBP7112P_01170	COG0028	Belongs to the TPP enzyme family
XcvCFBP7112P_01175	COG2205	protein histidine kinase activity
XcvCFBP7112P_01200	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
XcvCFBP7112P_01215	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XcvCFBP7112P_01225	COG0596	Alpha beta hydrolase
XcvCFBP7112P_01235	COG0318	PFAM AMP-dependent synthetase and ligase
XcvCFBP7112P_01250	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XcvCFBP7112P_01265	COG1181	Belongs to the D-alanine--D-alanine ligase family
XcvCFBP7112P_01280	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XcvCFBP7112P_01290	COG0564	pseudouridine synthase activity
XcvCFBP7112P_01310	COG1446	asparaginase
XcvCFBP7112P_01315	COG0339	signal peptide processing
XcvCFBP7112P_01355	COG0475	glutathione-regulated potassium exporter activity
XcvCFBP7112P_01360	COG0583	DNA-binding transcription factor activity
XcvCFBP7112P_01365	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
XcvCFBP7112P_01370	COG2224	Isocitrate lyase
XcvCFBP7112P_01375	COG3706	GGDEF domain
XcvCFBP7112P_01405	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XcvCFBP7112P_01410	COG1960	acyl-CoA dehydrogenase activity
XcvCFBP7112P_01480	COG0697	spore germination
XcvCFBP7112P_01490	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
XcvCFBP7112P_01495	COG1846	Transcriptional regulator
XcvCFBP7112P_01500	COG1764	response to oxidative stress
XcvCFBP7112P_01530	COG2130	NADP-dependent
XcvCFBP7112P_01545	COG1187	pseudouridine synthase activity
XcvCFBP7112P_01560	COG1643	Atp-dependent helicase
XcvCFBP7112P_01565	COG4807	Protein conserved in bacteria
XcvCFBP7112P_01570	COG2351	hydroxyisourate hydrolase activity
XcvCFBP7112P_01575	COG2072	flavoprotein involved in K transport
XcvCFBP7112P_01595	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
XcvCFBP7112P_01640	COG2252	PERMEase
XcvCFBP7112P_01665	COG0084	hydrolase, TatD family'
XcvCFBP7112P_01675	COG0583	DNA-binding transcription factor activity
XcvCFBP7112P_01680	COG2814	Major facilitator Superfamily
XcvCFBP7112P_01690	COG2267	carboxylic ester hydrolase activity
XcvCFBP7112P_01695	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
XcvCFBP7112P_01700	COG1902	pentaerythritol trinitrate reductase activity
XcvCFBP7112P_01720	COG0745	RESPONSE REGULATOR receiver
XcvCFBP7112P_01725	COG2205	protein histidine kinase activity
XcvCFBP7112P_01730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcvCFBP7112P_01740	COG1538	Outer membrane efflux protein
XcvCFBP7112P_01755	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XcvCFBP7112P_01760	COG0583	DNA-binding transcription factor activity
XcvCFBP7112P_01795	COG0702	epimerase
XcvCFBP7112P_01800	COG1733	regulation of RNA biosynthetic process
XcvCFBP7112P_01845	COG0129	dihydroxy-acid dehydratase activity
XcvCFBP7112P_01860	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
XcvCFBP7112P_01915	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
XcvCFBP7112P_01920	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
XcvCFBP7112P_01945	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
XcvCFBP7112P_01950	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
XcvCFBP7112P_01960	COG3485	protocatechuate 3,4-dioxygenase
XcvCFBP7112P_01965	COG3485	protocatechuate 3,4-dioxygenase
XcvCFBP7112P_01975	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XcvCFBP7112P_01980	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XcvCFBP7112P_01990	COG1414	Transcriptional regulator
XcvCFBP7112P_02010	COG0445	tRNA wobble uridine modification
XcvCFBP7112P_02045	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7112P_02050	COG2267	carboxylic ester hydrolase activity
XcvCFBP7112P_02060	COG0156	8-amino-7-oxononanoate synthase activity
XcvCFBP7112P_02065	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
XcvCFBP7112P_02070	COG1040	competence protein
XcvCFBP7112P_02075	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
XcvCFBP7112P_02115	COG5297	Belongs to the glycosyl hydrolase family 6
XcvCFBP7112P_02165	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XcvCFBP7112P_02240	COG1511	domain protein
XcvCFBP7112P_02240	COG3264	Mechanosensitive ion channel
XcvCFBP7112P_02245	COG1368	sulfuric ester hydrolase activity
XcvCFBP7112P_02255	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XcvCFBP7112P_02260	COG2354	Protein conserved in bacteria
XcvCFBP7112P_02265	COG3706	GGDEF domain
XcvCFBP7112P_02265	COG0745	RESPONSE REGULATOR receiver
XcvCFBP7112P_02270	COG0297	glycogen (starch) synthase activity
XcvCFBP7112P_02275	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XcvCFBP7112P_02280	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XcvCFBP7112P_02305	COG0702	epimerase
XcvCFBP7112P_02345	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcvCFBP7112P_02360	COG0513	Belongs to the DEAD box helicase family
XcvCFBP7112P_02365	COG0508	dehydrogenase complex catalyzes the overall conversion of
XcvCFBP7112P_02390	COG3483	tryptophan 2,3-dioxygenase activity
XcvCFBP7112P_02395	COG3104	oligopeptide transport
XcvCFBP7112P_02415	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
XcvCFBP7112P_02435	COG1320	monovalent cation:proton antiporter activity
XcvCFBP7112P_02440	COG2212	antiporter activity
XcvCFBP7112P_02450	COG0651	ATP synthesis coupled electron transport
XcvCFBP7112P_02455	COG1006	Multisubunit Na H antiporter MnhC subunit
XcvCFBP7112P_02460	COG2111	Na H antiporter
XcvCFBP7112P_02460	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XcvCFBP7112P_02485	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
XcvCFBP7112P_02490	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
XcvCFBP7112P_02505	COG0456	acetyltransferase
XcvCFBP7112P_02510	COG1597	lipid kinase activity
XcvCFBP7112P_02535	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
XcvCFBP7112P_02540	COG0134	indole-3-glycerol-phosphate synthase activity
XcvCFBP7112P_02550	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XcvCFBP7112P_02555	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
XcvCFBP7112P_02565	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
XcvCFBP7112P_02570	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
XcvCFBP7112P_02575	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
XcvCFBP7112P_02590	COG1051	belongs to the nudix hydrolase family
XcvCFBP7112P_02630	COG0316	Belongs to the HesB IscA family
XcvCFBP7112P_02650	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XcvCFBP7112P_02670	COG2814	Major facilitator Superfamily
XcvCFBP7112P_02680	COG2814	Major facilitator Superfamily
XcvCFBP7112P_02685	COG1289	transmembrane transporter activity
XcvCFBP7112P_02690	COG0151	Belongs to the GarS family
XcvCFBP7112P_02700	COG0138	bifunctional purine biosynthesis protein purh
XcvCFBP7112P_02705	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XcvCFBP7112P_02710	COG2267	carboxylic ester hydrolase activity
XcvCFBP7112P_02715	COG2453	phosphatase
XcvCFBP7112P_02715	COG0671	phosphoesterase, PA-phosphatase related
XcvCFBP7112P_02740	COG4589	Belongs to the CDS family
XcvCFBP7112P_02745	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
XcvCFBP7112P_02770	COG2264	protein methyltransferase activity
XcvCFBP7112P_02790	COG0439	Biotin carboxylase
XcvCFBP7112P_02800	COG0511	ligase activity, forming carbon-carbon bonds
XcvCFBP7112P_02805	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
XcvCFBP7112P_02815	COG1324	tolerance protein
XcvCFBP7112P_02845	COG0300	oxidoreductase activity
XcvCFBP7112P_02850	COG2356	endonuclease I
XcvCFBP7112P_02855	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
XcvCFBP7112P_02860	COG0459	protein refolding
XcvCFBP7112P_02865	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
XcvCFBP7112P_02895	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XcvCFBP7112P_02910	COG3386	PFAM SMP-30 Gluconolaconase
XcvCFBP7112P_02920	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
XcvCFBP7112P_02950	COG0778	Nitroreductase
XcvCFBP7112P_02955	COG2353	YceI-like domain
XcvCFBP7112P_02985	COG3052	prosthetic group binding
XcvCFBP7112P_03005	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
XcvCFBP7112P_03010	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XcvCFBP7112P_03020	COG1802	Transcriptional regulator
XcvCFBP7112P_03140	COG1082	Xylose isomerase domain protein TIM barrel
XcvCFBP7112P_03150	COG4221	oxidoreductase activity
XcvCFBP7112P_03160	COG0435	Glutathione S-transferase
XcvCFBP7112P_03195	COG1506	peptidase
XcvCFBP7112P_03195	COG0823	Involved in the tonB-independent uptake of proteins
XcvCFBP7112P_03215	COG3706	GGDEF domain
XcvCFBP7112P_03240	COG0697	spore germination
XcvCFBP7112P_03245	COG4305	rare lipoprotein A
XcvCFBP7112P_03250	COG5297	Belongs to the glycosyl hydrolase family 6
XcvCFBP7112P_03260	COG1113	amino acid transport
XcvCFBP7112P_03270	COG0598	Magnesium transport protein CorA
XcvCFBP7112P_03280	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
XcvCFBP7112P_03330	COG0840	transmembrane signaling receptor activity
XcvCFBP7112P_03335	COG5297	Belongs to the glycosyl hydrolase family 6
XcvCFBP7112P_03335	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XcvCFBP7112P_03340	COG0659	secondary active sulfate transmembrane transporter activity
XcvCFBP7112P_03345	COG3706	GGDEF domain
XcvCFBP7112P_03365	COG2943	transferase activity, transferring hexosyl groups
XcvCFBP7112P_03375	COG3275	phosphorelay sensor kinase activity
XcvCFBP7112P_03385	COG0181	hydroxymethylbilane synthase activity
XcvCFBP7112P_03415	COG1505	serine-type exopeptidase activity
XcvCFBP7112P_03430	COG2832	Protein of unknown function (DUF454)
XcvCFBP7112P_03440	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
XcvCFBP7112P_03450	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XcvCFBP7112P_03455	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
XcvCFBP7112P_03460	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
XcvCFBP7112P_03485	COG2226	methyltransferase
XcvCFBP7112P_03490	COG3300	MHYT domain
XcvCFBP7112P_03490	COG5001	Diguanylate cyclase
XcvCFBP7112P_03495	COG0308	aminopeptidase N
XcvCFBP7112P_03545	COG3284	Transcriptional regulator
XcvCFBP7112P_03555	COG1077	Cell shape determining protein MreB Mrl
XcvCFBP7112P_03560	COG1792	Involved in formation and maintenance of cell shape
XcvCFBP7112P_03575	COG0772	Belongs to the SEDS family
XcvCFBP7112P_03585	COG2951	lytic endotransglycosylase activity
XcvCFBP7112P_03590	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XcvCFBP7112P_03600	COG1686	Belongs to the peptidase S11 family
XcvCFBP7112P_03610	COG2921	Belongs to the UPF0250 family
XcvCFBP7112P_03615	COG0321	lipoyl(octanoyl) transferase activity
XcvCFBP7112P_03620	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
XcvCFBP7112P_03635	COG0583	DNA-binding transcription factor activity
XcvCFBP7112P_03645	COG1051	belongs to the nudix hydrolase family
XcvCFBP7112P_03645	COG1056	cytidyltransferase-related domain
XcvCFBP7112P_03680	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
XcvCFBP7112P_03685	COG0673	inositol 2-dehydrogenase activity
XcvCFBP7112P_03690	COG2823	Periplasmic or secreted lipoprotein
XcvCFBP7112P_03695	COG4251	negative regulation of phosphorylation
XcvCFBP7112P_03700	COG0784	Response regulator, receiver
XcvCFBP7112P_03705	COG4191	Histidine kinase
XcvCFBP7112P_03710	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XcvCFBP7112P_03765	COG1459	type II secretion system
XcvCFBP7112P_03770	COG2165	general secretion pathway protein
XcvCFBP7112P_03785	COG4795	General secretion pathway protein
XcvCFBP7112P_03815	COG3250	beta-galactosidase activity
XcvCFBP7112P_03840	COG1609	Transcriptional regulator
XcvCFBP7112P_03845	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XcvCFBP7112P_03850	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
XcvCFBP7112P_03865	COG0617	tRNA 3'-terminal CCA addition
XcvCFBP7112P_03870	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
XcvCFBP7112P_03875	COG1012	belongs to the aldehyde dehydrogenase family
XcvCFBP7112P_03895	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XcvCFBP7112P_03910	COG0218	Necessary for normal cell division and for the maintenance of normal septation
XcvCFBP7112P_03915	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XcvCFBP7112P_03935	COG2205	protein histidine kinase activity
XcvCFBP7112P_03940	COG0745	RESPONSE REGULATOR receiver
XcvCFBP7112P_03965	COG3791	Glutathione-dependent formaldehyde-activating
XcvCFBP7112P_03980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XcvCFBP7112P_03990	COG0697	spore germination
XcvCFBP7112P_04000	COG0488	(ABC) transporter
XcvCFBP7112P_04010	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
XcvCFBP7112P_04015	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
XcvCFBP7112P_04025	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XcvCFBP7112P_04025	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XcvCFBP7112P_04045	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
XcvCFBP7112P_04050	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XcvCFBP7112P_04055	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
XcvCFBP7112P_04085	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
XcvCFBP7112P_04090	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
XcvCFBP7112P_04095	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
XcvCFBP7112P_04100	COG2205	protein histidine kinase activity
XcvCFBP7112P_04105	COG0745	RESPONSE REGULATOR receiver
XcvCFBP7112P_04110	COG0277	FAD linked oxidase domain protein
XcvCFBP7112P_04115	COG1988	membrane-bound metal-dependent
XcvCFBP7112P_04120	COG0792	nuclease activity
XcvCFBP7112P_04145	COG2001	Belongs to the MraZ family
XcvCFBP7112P_04150	COG0275	rRNA processing
XcvCFBP7112P_04155	COG3116	cell division
XcvCFBP7112P_04165	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
XcvCFBP7112P_04170	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
XcvCFBP7112P_04175	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XcvCFBP7112P_04185	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
XcvCFBP7112P_04190	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XcvCFBP7112P_04195	COG1181	Belongs to the D-alanine--D-alanine ligase family
XcvCFBP7112P_04200	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
XcvCFBP7112P_04215	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
XcvCFBP7112P_04225	COG0739	heme binding
XcvCFBP7112P_04230	COG0653	protein targeting
XcvCFBP7112P_04235	COG0494	nUDIX hydrolase
XcvCFBP7112P_04245	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XcvCFBP7112P_04260	COG0604	alcohol dehydrogenase
XcvCFBP7112P_04260	COG3321	synthase
XcvCFBP7112P_04260	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7112P_04285	COG0366	Alpha amylase catalytic
XcvCFBP7112P_04325	COG2226	methyltransferase
XcvCFBP7112P_04330	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
XcvCFBP7112P_04340	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
XcvCFBP7112P_04380	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
XcvCFBP7112P_04390	COG4106	trans-aconitate 2-methyltransferase activity
XcvCFBP7112P_04395	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XcvCFBP7112P_04405	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XcvCFBP7112P_04410	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
XcvCFBP7112P_04420	COG0667	Aldo Keto reductase
XcvCFBP7112P_04430	COG4771	TonB-dependent receptor
XcvCFBP7112P_04450	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XcvCFBP7112P_04455	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
XcvCFBP7112P_04465	COG2175	clavaminate synthase activity
XcvCFBP7112P_04475	COG4181	ATPase activity
XcvCFBP7112P_04490	COG0642	Histidine kinase
XcvCFBP7112P_04500	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
XcvCFBP7112P_04520	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
XcvCFBP7112P_04525	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
XcvCFBP7112P_04540	COG3829	transcription factor binding
XcvCFBP7112P_04550	COG1116	anion transmembrane transporter activity
XcvCFBP7112P_04555	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XcvCFBP7112P_04565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XcvCFBP7112P_04570	COG0431	NADPH-dependent FMN reductase
XcvCFBP7112P_04590	COG0747	negative chemotaxis
XcvCFBP7112P_04610	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
XcvCFBP7112P_04615	COG2967	ApaG domain
XcvCFBP7112P_04620	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
XcvCFBP7112P_04625	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
XcvCFBP7112P_04630	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XcvCFBP7112P_04635	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
XcvCFBP7112P_04640	COG0123	including yeast histone deacetylase and acetoin utilization protein
XcvCFBP7112P_04645	COG2096	Adenosyltransferase
XcvCFBP7112P_04660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XcvCFBP7112P_04665	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XcvCFBP7112P_04695	COG3384	dioxygenase
XcvCFBP7112P_04700	COG0583	DNA-binding transcription factor activity
XcvCFBP7112P_04715	COG1024	Enoyl-CoA hydratase
XcvCFBP7112P_04745	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
XcvCFBP7112P_04770	COG0697	spore germination
XcvCFBP7112P_04780	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XcvCFBP7112P_04800	COG3706	GGDEF domain
XcvCFBP7112P_04800	COG0745	RESPONSE REGULATOR receiver
XcvCFBP7112P_04810	COG2197	response regulator
XcvCFBP7112P_04820	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XcvCFBP7112P_04830	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
XcvCFBP7112P_04835	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XcvCFBP7112P_04845	COG0583	DNA-binding transcription factor activity
XcvCFBP7112P_04850	COG3634	alkyl hydroperoxide reductase activity
XcvCFBP7112P_04860	COG2890	protein-(glutamine-N5) methyltransferase activity
XcvCFBP7112P_04880	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XcvCFBP7112P_04880	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XcvCFBP7112P_04910	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
XcvCFBP7112P_04930	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
XcvCFBP7112P_04950	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XcvCFBP7112P_04955	COG1404	Belongs to the peptidase S8 family
XcvCFBP7112P_04965	COG1404	Belongs to the peptidase S8 family
XcvCFBP7112P_04970	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
XcvCFBP7112P_04995	COG1295	ribonuclease BN
XcvCFBP7112P_05000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XcvCFBP7112P_05005	COG1254	Belongs to the acylphosphatase family
XcvCFBP7112P_05020	COG0521	Mo-molybdopterin cofactor biosynthetic process
XcvCFBP7112P_05030	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
XcvCFBP7112P_05035	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
XcvCFBP7112P_05045	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
XcvCFBP7112P_05050	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
XcvCFBP7112P_05060	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
XcvCFBP7112P_05065	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
XcvCFBP7112P_05070	COG0193	aminoacyl-tRNA hydrolase activity
XcvCFBP7112P_05075	COG0012	GTP binding
XcvCFBP7112P_05095	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XcvCFBP7112P_05105	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
XcvCFBP7112P_05110	COG0250	Participates in transcription elongation, termination and antitermination
XcvCFBP7112P_05115	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
XcvCFBP7112P_05120	COG0081	regulation of translation
XcvCFBP7112P_05125	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
XcvCFBP7112P_05130	COG0222	ribosome binding
XcvCFBP7112P_05135	COG0085	RNA polymerase activity
XcvCFBP7112P_05140	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
XcvCFBP7112P_05145	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
XcvCFBP7112P_05150	COG0049	tRNA binding
XcvCFBP7112P_05155	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
XcvCFBP7112P_05160	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XcvCFBP7112P_05165	COG0051	transcription antitermination factor activity, RNA binding
XcvCFBP7112P_05170	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
XcvCFBP7112P_05175	COG0088	Forms part of the polypeptide exit tunnel
XcvCFBP7112P_05185	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XcvCFBP7112P_05190	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
XcvCFBP7112P_05195	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
XcvCFBP7112P_05200	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
XcvCFBP7112P_05205	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
XcvCFBP7112P_05210	COG0255	Belongs to the universal ribosomal protein uL29 family
XcvCFBP7112P_05215	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
XcvCFBP7112P_05220	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
XcvCFBP7112P_05225	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
XcvCFBP7112P_05230	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
XcvCFBP7112P_05235	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
XcvCFBP7112P_05240	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
XcvCFBP7112P_05245	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
XcvCFBP7112P_05250	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
XcvCFBP7112P_05255	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
XcvCFBP7112P_05260	COG1841	ribosomal large subunit assembly
XcvCFBP7112P_05265	COG0200	Binds to the 23S rRNA
XcvCFBP7112P_05270	COG0201	protein transport
XcvCFBP7112P_05275	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
XcvCFBP7112P_05280	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
XcvCFBP7112P_05285	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
XcvCFBP7112P_05290	COG0202	RNA polymerase activity
XcvCFBP7112P_05295	COG0203	ribosomal protein L17
XcvCFBP7112P_05300	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
XcvCFBP7112P_05320	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
XcvCFBP7112P_05335	COG0154	amidase activity
XcvCFBP7112P_05350	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XcvCFBP7112P_05355	COG0039	L-malate dehydrogenase activity
XcvCFBP7112P_05360	COG0625	glutathione transferase activity
XcvCFBP7112P_05375	COG0446	pyridine nucleotide-disulphide oxidoreductase
XcvCFBP7112P_05375	COG1902	pentaerythritol trinitrate reductase activity
XcvCFBP7112P_05410	COG0156	8-amino-7-oxononanoate synthase activity
XcvCFBP7112P_05420	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
XcvCFBP7112P_05425	COG4208	sulfate ABC transporter
XcvCFBP7112P_05430	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
XcvCFBP7112P_05440	COG1063	alcohol dehydrogenase
XcvCFBP7112P_05460	COG0406	alpha-ribazole phosphatase activity
XcvCFBP7112P_05465	COG0285	dihydrofolate synthase activity
XcvCFBP7112P_05485	COG2833	Protein of unknown function (DUF455)
XcvCFBP7112P_05505	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XcvCFBP7112P_05510	COG0671	phosphoesterase, PA-phosphatase related
XcvCFBP7112P_05515	COG0438	transferase activity, transferring glycosyl groups
XcvCFBP7112P_05525	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
XcvCFBP7112P_05540	COG4783	chaperone-mediated protein folding
XcvCFBP7112P_05555	COG0473	3-isopropylmalate dehydrogenase activity
XcvCFBP7112P_05785	COG3179	chitinase
XcvCFBP7112P_05830	COG4695	Portal protein
XcvCFBP7112P_05840	COG0863	Belongs to the N(4) N(6)-methyltransferase family
XcvCFBP7112P_05845	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
XcvCFBP7112P_05875	COG0544	peptidyl-prolyl cis-trans isomerase activity
XcvCFBP7112P_05880	COG0740	serine-type endopeptidase activity
XcvCFBP7112P_05885	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
XcvCFBP7112P_05915	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XcvCFBP7112P_05925	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XcvCFBP7112P_05935	COG0328	RNA-DNA hybrid ribonuclease activity
XcvCFBP7112P_05940	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XcvCFBP7112P_05945	COG0631	protein serine/threonine phosphatase activity
XcvCFBP7112P_05960	COG0859	PFAM glycosyl transferase family 9
XcvCFBP7112P_05965	COG3642	lipopolysaccharide core region biosynthetic process
XcvCFBP7112P_05970	COG1234	tRNA 3'-trailer cleavage
XcvCFBP7112P_05975	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
XcvCFBP7112P_05985	COG0315	cyclic pyranopterin monophosphate synthase activity
XcvCFBP7112P_05990	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
XcvCFBP7112P_05995	COG0314	molybdopterin synthase activity
XcvCFBP7112P_06015	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
XcvCFBP7112P_06020	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
XcvCFBP7112P_06025	COG0537	adenosine 5'-monophosphoramidase activity
XcvCFBP7112P_06045	COG0714	Associated with various cellular activities
XcvCFBP7112P_06070	COG0424	maF-like protein
XcvCFBP7112P_06075	COG1399	metal-binding, possibly nucleic acid-binding protein
XcvCFBP7112P_06085	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XcvCFBP7112P_06095	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XcvCFBP7112P_06105	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XcvCFBP7112P_06115	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
XcvCFBP7112P_06120	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XcvCFBP7112P_06145	COG3829	transcription factor binding
XcvCFBP7112P_06190	COG2373	Large extracellular alpha-helical protein
XcvCFBP7112P_06210	COG4953	penicillin-binding protein 1C
XcvCFBP7112P_06220	COG0678	peroxiredoxin activity
XcvCFBP7112P_06240	COG0330	HflC and HflK could
XcvCFBP7112P_06245	COG0330	HflC and HflK could
XcvCFBP7112P_06255	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
XcvCFBP7112P_06260	COG0308	aminopeptidase N
XcvCFBP7112P_06270	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7112P_06275	COG1309	transcriptional regulator
XcvCFBP7112P_06330	COG0732	type I restriction modification DNA specificity domain
XcvCFBP7112P_06335	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
XcvCFBP7112P_06375	COG0328	RNA-DNA hybrid ribonuclease activity
XcvCFBP7112P_06375	COG0406	alpha-ribazole phosphatase activity
XcvCFBP7112P_06380	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XcvCFBP7112P_06395	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7112P_06400	COG3537	Alpha-1,2-mannosidase
XcvCFBP7112P_06405	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7112P_06420	COG0492	ferredoxin-NADP+ reductase activity
XcvCFBP7112P_06465	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XcvCFBP7112P_06470	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XcvCFBP7112P_06475	COG2080	2 iron, 2 sulfur cluster binding
XcvCFBP7112P_06510	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XcvCFBP7112P_06525	COG0587	DNA-directed DNA polymerase activity
XcvCFBP7112P_06555	COG0823	Involved in the tonB-independent uptake of proteins
XcvCFBP7112P_06555	COG1506	peptidase
XcvCFBP7112P_06575	COG1917	Cupin 2, conserved barrel domain protein
XcvCFBP7112P_06575	COG2207	Transcriptional regulator
XcvCFBP7112P_06595	COG0753	catalase activity
XcvCFBP7112P_06600	COG0656	L-ascorbic acid biosynthetic process
XcvCFBP7112P_06610	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XcvCFBP7112P_06610	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XcvCFBP7112P_06615	COG2814	Major facilitator Superfamily
XcvCFBP7112P_06630	COG2194	sulfuric ester hydrolase activity
XcvCFBP7112P_06645	COG0745	RESPONSE REGULATOR receiver
XcvCFBP7112P_06650	COG0642	Histidine kinase
XcvCFBP7112P_06660	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
XcvCFBP7112P_06665	COG2894	cell division
XcvCFBP7112P_06670	COG0850	regulation of cytokinetic process
XcvCFBP7112P_06685	COG4585	Histidine kinase
XcvCFBP7112P_06690	COG2197	response regulator
XcvCFBP7112P_06705	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
XcvCFBP7112P_06730	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
XcvCFBP7112P_06740	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
XcvCFBP7112P_06760	COG1946	Acyl-CoA thioesterase
XcvCFBP7112P_06775	COG0824	Thioesterase
XcvCFBP7112P_06780	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
XcvCFBP7112P_06785	COG0261	This protein binds to 23S rRNA in the presence of protein L20
XcvCFBP7112P_06790	COG0211	Belongs to the bacterial ribosomal protein bL27 family
XcvCFBP7112P_06795	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
XcvCFBP7112P_06800	COG0268	Binds directly to 16S ribosomal RNA
XcvCFBP7112P_06810	COG0196	riboflavin kinase activity
XcvCFBP7112P_06815	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
XcvCFBP7112P_06820	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
XcvCFBP7112P_06825	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
XcvCFBP7112P_06860	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XcvCFBP7112P_06865	COG1845	cytochrome c oxidase, subunit III
XcvCFBP7112P_06870	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
XcvCFBP7112P_06895	COG2207	Transcriptional regulator
XcvCFBP7112P_06900	COG0326	Molecular chaperone. Has ATPase activity
XcvCFBP7112P_06910	COG1366	Belongs to the anti-sigma-factor antagonist family
XcvCFBP7112P_06920	COG2172	sigma factor antagonist activity
XcvCFBP7112P_06945	COG4771	TonB-dependent receptor
XcvCFBP7112P_06955	COG5507	3-demethylubiquinone-9 3-methyltransferase
XcvCFBP7112P_06965	COG2205	protein histidine kinase activity
XcvCFBP7112P_06975	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XcvCFBP7112P_06980	COG4999	Histidine kinase
XcvCFBP7112P_06980	COG2205	protein histidine kinase activity
XcvCFBP7112P_06980	COG3437	response regulator, receiver
XcvCFBP7112P_06980	COG3850	Histidine kinase
XcvCFBP7112P_06985	COG4191	Histidine kinase
XcvCFBP7112P_06985	COG0784	Response regulator, receiver
XcvCFBP7112P_07010	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XcvCFBP7112P_07020	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XcvCFBP7112P_07030	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XcvCFBP7112P_07035	COG0228	four-way junction DNA binding
XcvCFBP7112P_07040	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
XcvCFBP7112P_07045	COG0336	Belongs to the RNA methyltransferase TrmD family
XcvCFBP7112P_07050	COG0335	large ribosomal subunit rRNA binding
XcvCFBP7112P_07055	COG0534	Mate efflux family protein
XcvCFBP7112P_07080	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
XcvCFBP7112P_07090	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
XcvCFBP7112P_07120	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
XcvCFBP7112P_07190	COG3483	tryptophan 2,3-dioxygenase activity
XcvCFBP7112P_07230	COG3250	beta-galactosidase activity
XcvCFBP7112P_07235	COG3867	Arabinogalactan endo-beta-1,4-galactanase
XcvCFBP7112P_07255	COG1960	acyl-CoA dehydrogenase activity
XcvCFBP7112P_07260	COG1024	Enoyl-CoA hydratase
XcvCFBP7112P_07265	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
XcvCFBP7112P_07305	COG1250	3-hydroxyacyl-CoA dehydrogenase
XcvCFBP7112P_07305	COG1024	Enoyl-CoA hydratase
XcvCFBP7112P_07320	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XcvCFBP7112P_07325	COG0481	GTPase activity
XcvCFBP7112P_07340	COG0571	ribonuclease III activity
XcvCFBP7112P_07345	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
XcvCFBP7112P_07350	COG1381	Involved in DNA repair and RecF pathway recombination
XcvCFBP7112P_07360	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
XcvCFBP7112P_07370	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
XcvCFBP7112P_07375	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
XcvCFBP7112P_07380	COG3046	protein related to deoxyribodipyrimidine photolyase
XcvCFBP7112P_07385	COG1472	Belongs to the glycosyl hydrolase 3 family
XcvCFBP7112P_07395	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
XcvCFBP7112P_07400	COG1278	Cold shock
XcvCFBP7112P_07405	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XcvCFBP7112P_07415	COG1201	RNA secondary structure unwinding
XcvCFBP7112P_07420	COG1793	dna ligase
XcvCFBP7112P_07430	COG1793	dna ligase
XcvCFBP7112P_07430	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XcvCFBP7112P_07445	COG0745	RESPONSE REGULATOR receiver
XcvCFBP7112P_07445	COG3706	GGDEF domain
XcvCFBP7112P_07460	COG0183	Belongs to the thiolase family
XcvCFBP7112P_07480	COG1451	nucleotide metabolic process
XcvCFBP7112P_07485	COG5487	UPF0391 membrane protein
XcvCFBP7112P_07495	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XcvCFBP7112P_07510	COG1077	Cell shape determining protein MreB Mrl
XcvCFBP7112P_07515	COG1047	Peptidyl-prolyl cis-trans
XcvCFBP7112P_07525	COG2824	Alkylphosphonate utilization operon protein PhnA
XcvCFBP7112P_07535	COG1902	pentaerythritol trinitrate reductase activity
XcvCFBP7112P_07540	COG2814	Major facilitator Superfamily
XcvCFBP7112P_07575	COG0392	lysyltransferase activity
XcvCFBP7112P_07575	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
XcvCFBP7112P_07585	COG0251	oxidation-reduction process
XcvCFBP7112P_07590	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XcvCFBP7112P_07605	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XcvCFBP7112P_07630	COG1595	DNA-templated transcription, initiation
XcvCFBP7112P_07655	COG2878	Part of a membrane complex involved in electron transport
XcvCFBP7112P_07665	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XcvCFBP7112P_07665	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XcvCFBP7112P_07680	COG1131	(ABC) transporter
XcvCFBP7112P_07685	COG0346	lactoylglutathione lyase activity
XcvCFBP7112P_07690	COG0833	amino acid
XcvCFBP7112P_07695	COG2040	homocysteine
XcvCFBP7112P_07705	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XcvCFBP7112P_07725	COG1695	Transcriptional regulator
XcvCFBP7112P_07760	COG0825	malonyl-CoA metabolic process
XcvCFBP7112P_07775	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XcvCFBP7112P_07780	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XcvCFBP7112P_07785	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XcvCFBP7112P_07790	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XcvCFBP7112P_07805	COG0750	zinc metalloprotease
XcvCFBP7112P_07810	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
XcvCFBP7112P_07820	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
XcvCFBP7112P_07825	COG0233	cytoplasmic translational termination
XcvCFBP7112P_07830	COG0528	UMP kinase activity
XcvCFBP7112P_07835	COG0745	RESPONSE REGULATOR receiver
XcvCFBP7112P_07835	COG3706	GGDEF domain
XcvCFBP7112P_07840	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
XcvCFBP7112P_07845	COG0052	Belongs to the universal ribosomal protein uS2 family
XcvCFBP7112P_07880	COG0024	Methionine aminopeptidase
XcvCFBP7112P_07885	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
XcvCFBP7112P_07895	COG1393	Belongs to the ArsC family
XcvCFBP7112P_07900	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XcvCFBP7112P_07905	COG0367	asparagine synthase
XcvCFBP7112P_07915	COG4774	siderophore transport
XcvCFBP7112P_07955	COG1566	PFAM secretion protein HlyD family protein
XcvCFBP7112P_07960	COG2814	Major facilitator Superfamily
XcvCFBP7112P_08015	COG0339	signal peptide processing
XcvCFBP7112P_08020	COG0386	Belongs to the glutathione peroxidase family
XcvCFBP7112P_08040	COG0625	glutathione transferase activity
XcvCFBP7112P_08075	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
XcvCFBP7112P_08080	COG0084	hydrolase, TatD family'
XcvCFBP7112P_08095	COG1960	acyl-CoA dehydrogenase activity
XcvCFBP7112P_08115	COG0367	asparagine synthase
XcvCFBP7112P_08125	COG0305	Participates in initiation and elongation during chromosome replication
XcvCFBP7112P_08130	COG0415	Belongs to the DNA photolyase family
XcvCFBP7112P_08145	COG0583	DNA-binding transcription factor activity
XcvCFBP7112P_08180	COG3706	GGDEF domain
XcvCFBP7112P_08190	COG3706	GGDEF domain
XcvCFBP7112P_08215	COG0582	viral genome integration into host DNA
XcvCFBP7112P_08230	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
XcvCFBP7112P_08245	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XcvCFBP7112P_08255	COG0497	DNA recombination
XcvCFBP7112P_08260	COG1420	regulation of RNA biosynthetic process
XcvCFBP7112P_08265	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XcvCFBP7112P_08270	COG0443	Heat shock 70 kDa protein
XcvCFBP7112P_08275	COG0484	heat shock protein binding
XcvCFBP7112P_08285	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
XcvCFBP7112P_08315	COG0583	DNA-binding transcription factor activity
XcvCFBP7112P_08320	COG1132	(ABC) transporter
XcvCFBP7112P_08355	COG2850	peptidyl-arginine hydroxylation
XcvCFBP7112P_08375	COG1253	flavin adenine dinucleotide binding
XcvCFBP7112P_08410	COG1131	(ABC) transporter
XcvCFBP7112P_08415	COG1725	Transcriptional regulator
XcvCFBP7112P_08425	COG0386	Belongs to the glutathione peroxidase family
XcvCFBP7112P_08440	COG2900	Belongs to the SlyX family
XcvCFBP7112P_08465	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XcvCFBP7112P_08475	COG1410	methionine synthase
XcvCFBP7112P_08475	COG0646	methionine synthase
XcvCFBP7112P_08480	COG0646	methionine synthase
XcvCFBP7112P_08480	COG1410	methionine synthase
XcvCFBP7112P_08490	COG1960	acyl-CoA dehydrogenase activity
XcvCFBP7112P_08495	COG1960	acyl-CoA dehydrogenase activity
XcvCFBP7112P_08525	COG0557	exoribonuclease II activity
XcvCFBP7112P_08535	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XcvCFBP7112P_08540	COG3706	GGDEF domain
XcvCFBP7112P_08545	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XcvCFBP7112P_08555	COG0704	Plays a role in the regulation of phosphate uptake
XcvCFBP7112P_08560	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
XcvCFBP7112P_08565	COG0581	inorganic phosphate transmembrane transporter activity
XcvCFBP7112P_08570	COG0573	inorganic phosphate transmembrane transporter activity
XcvCFBP7112P_08575	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XcvCFBP7112P_08600	COG0659	secondary active sulfate transmembrane transporter activity
XcvCFBP7112P_08605	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
XcvCFBP7112P_08615	COG1024	Enoyl-CoA hydratase
XcvCFBP7112P_08625	COG0494	nUDIX hydrolase
XcvCFBP7112P_08670	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XcvCFBP7112P_08670	COG0116	Belongs to the methyltransferase superfamily
XcvCFBP7112P_08675	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
XcvCFBP7112P_08695	COG2925	Exonuclease
XcvCFBP7112P_08700	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XcvCFBP7112P_08705	COG3844	kynureninase activity
XcvCFBP7112P_08715	COG0662	Cupin 2, conserved barrel domain protein
XcvCFBP7112P_08720	COG0288	reversible hydration of carbon dioxide
XcvCFBP7112P_08800	COG0017	Asparaginyl-tRNA synthetase
XcvCFBP7112P_08810	COG0316	Belongs to the HesB IscA family
XcvCFBP7112P_08815	COG0360	Binds together with S18 to 16S ribosomal RNA
XcvCFBP7112P_08820	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
XcvCFBP7112P_08825	COG0359	binds to the 23S rRNA
XcvCFBP7112P_08840	COG3115	cell septum assembly
XcvCFBP7112P_08850	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XcvCFBP7112P_08855	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
XcvCFBP7112P_08860	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
XcvCFBP7112P_08875	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
XcvCFBP7112P_08885	COG4993	Dehydrogenase
XcvCFBP7112P_08895	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
XcvCFBP7112P_08905	COG2986	histidine ammonia-lyase
XcvCFBP7112P_08910	COG1228	amidohydrolase
XcvCFBP7112P_08955	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
XcvCFBP7112P_08960	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XcvCFBP7112P_08965	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
XcvCFBP7112P_08970	COG0077	Prephenate dehydratase
XcvCFBP7112P_08970	COG1605	Chorismate mutase
XcvCFBP7112P_08975	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
XcvCFBP7112P_08990	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
XcvCFBP7112P_08995	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XcvCFBP7112P_09000	COG0583	DNA-binding transcription factor activity
XcvCFBP7112P_09015	COG0840	transmembrane signaling receptor activity
XcvCFBP7112P_09050	COG0784	Response regulator, receiver
XcvCFBP7112P_09050	COG4191	Histidine kinase
XcvCFBP7112P_09065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XcvCFBP7112P_09075	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
XcvCFBP7112P_09085	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XcvCFBP7112P_09100	COG1595	DNA-templated transcription, initiation
XcvCFBP7112P_09155	COG2244	polysaccharide biosynthetic process
XcvCFBP7112P_09185	COG2264	protein methyltransferase activity
XcvCFBP7112P_09210	COG1136	(ABC) transporter
XcvCFBP7112P_09225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XcvCFBP7112P_09240	COG1253	flavin adenine dinucleotide binding
XcvCFBP7112P_09255	COG0306	phosphate transporter
XcvCFBP7112P_09280	COG0504	CTP synthase activity
XcvCFBP7112P_09295	COG0148	phosphopyruvate hydratase activity
XcvCFBP7112P_09300	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
XcvCFBP7112P_09305	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
XcvCFBP7112P_09310	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
XcvCFBP7112P_09315	COG0585	pseudouridine synthase activity
XcvCFBP7112P_09320	COG2840	Smr protein MutS2
XcvCFBP7112P_09325	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
XcvCFBP7112P_09330	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XcvCFBP7112P_09335	COG1238	metal cluster binding
XcvCFBP7112P_09350	COG1534	Rna-binding protein
XcvCFBP7112P_09355	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
XcvCFBP7112P_09360	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
XcvCFBP7112P_09365	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
XcvCFBP7112P_09370	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
XcvCFBP7112P_09375	COG1923	regulation of RNA biosynthetic process
XcvCFBP7112P_09380	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
XcvCFBP7112P_09385	COG1546	Belongs to the CinA family
XcvCFBP7112P_09395	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XcvCFBP7112P_09400	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
XcvCFBP7112P_09410	COG2137	regulation of response to DNA damage stimulus
XcvCFBP7112P_09415	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
XcvCFBP7112P_09420	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
XcvCFBP7112P_09440	COG1741	Belongs to the pirin family
XcvCFBP7112P_09445	COG0583	DNA-binding transcription factor activity
XcvCFBP7112P_09470	COG0351	phosphomethylpyrimidine kinase
XcvCFBP7112P_09485	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
XcvCFBP7112P_09490	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XcvCFBP7112P_09505	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XcvCFBP7112P_09515	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
XcvCFBP7112P_09520	COG3734	2-keto-3-deoxy-galactonokinase
XcvCFBP7112P_09530	COG4948	Mandelate Racemase Muconate Lactonizing
XcvCFBP7112P_09535	COG0800	Aldolase
XcvCFBP7112P_09590	COG1501	Belongs to the glycosyl hydrolase 31 family
XcvCFBP7112P_09600	COG1070	Carbohydrate kinase
XcvCFBP7112P_09605	COG2115	Belongs to the xylose isomerase family
XcvCFBP7112P_09610	COG0477	Major facilitator Superfamily
XcvCFBP7112P_09635	COG0860	N-Acetylmuramoyl-L-alanine amidase
XcvCFBP7112P_09640	COG1469	GTP cyclohydrolase I activity
XcvCFBP7112P_09660	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
XcvCFBP7112P_09665	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
XcvCFBP7112P_09670	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
XcvCFBP7112P_09695	COG1472	Belongs to the glycosyl hydrolase 3 family
XcvCFBP7112P_09710	COG2203	Gaf domain
XcvCFBP7112P_09710	COG3706	GGDEF domain
XcvCFBP7112P_09710	COG5001	Diguanylate cyclase
XcvCFBP7112P_09710	COG4251	negative regulation of phosphorylation
XcvCFBP7112P_09725	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
XcvCFBP7112P_09735	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
XcvCFBP7112P_09740	COG0671	phosphoesterase, PA-phosphatase related
XcvCFBP7112P_09750	COG1794	racemase activity, acting on amino acids and derivatives
XcvCFBP7112P_09760	COG0697	spore germination
XcvCFBP7112P_09765	COG0812	UDP-N-acetylmuramate dehydrogenase activity
XcvCFBP7112P_09770	COG0167	dihydroorotate dehydrogenase activity
XcvCFBP7112P_09785	COG1012	belongs to the aldehyde dehydrogenase family
XcvCFBP7112P_09795	COG2963	transposase activity
XcvCFBP7112P_09810	COG1215	transferase activity, transferring glycosyl groups
XcvCFBP7112P_09815	COG1649	PFAM Uncharacterised BCR, COG1649
XcvCFBP7112P_09815	COG0726	polysaccharide deacetylase
XcvCFBP7112P_09870	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
XcvCFBP7112P_09905	COG0124	histidyl-tRNA synthetase
XcvCFBP7112P_09915	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
XcvCFBP7112P_09920	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
XcvCFBP7112P_09925	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XcvCFBP7112P_09930	COG0131	Imidazoleglycerol-phosphate dehydratase
XcvCFBP7112P_09930	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
XcvCFBP7112P_09935	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
XcvCFBP7112P_09940	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
XcvCFBP7112P_09945	COG0107	imidazoleglycerol-phosphate synthase activity
XcvCFBP7112P_09950	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
XcvCFBP7112P_09950	COG0140	phosphoribosyl-ATP diphosphatase activity
XcvCFBP7112P_09965	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
XcvCFBP7112P_09970	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
XcvCFBP7112P_09975	COG0235	Class ii aldolase
XcvCFBP7112P_09980	COG0531	amino acid
XcvCFBP7112P_09985	COG0531	amino acid
XcvCFBP7112P_09995	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XcvCFBP7112P_10000	COG0277	FAD linked oxidase domain protein
XcvCFBP7112P_10020	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XcvCFBP7112P_10065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XcvCFBP7112P_10070	COG2258	MOSC domain
XcvCFBP7112P_10075	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
XcvCFBP7112P_10080	COG0505	Belongs to the CarA family
XcvCFBP7112P_10090	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
XcvCFBP7112P_10095	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XcvCFBP7112P_10140	COG2963	transposase activity
XcvCFBP7112P_10150	COG3279	Response regulator of the LytR AlgR family
XcvCFBP7112P_10155	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
XcvCFBP7112P_10160	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
XcvCFBP7112P_10175	COG0784	Response regulator, receiver
XcvCFBP7112P_10175	COG2198	Histidine kinase
XcvCFBP7112P_10175	COG2205	protein histidine kinase activity
XcvCFBP7112P_10180	COG1024	Enoyl-CoA hydratase
XcvCFBP7112P_10185	COG0318	PFAM AMP-dependent synthetase and ligase
XcvCFBP7112P_10215	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XcvCFBP7112P_10225	COG2201	protein-glutamate methylesterase activity
XcvCFBP7112P_10230	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
XcvCFBP7112P_10240	COG0840	transmembrane signaling receptor activity
XcvCFBP7112P_10255	COG0835	chemotaxis
XcvCFBP7112P_10280	COG0840	transmembrane signaling receptor activity
XcvCFBP7112P_10285	COG0840	transmembrane signaling receptor activity
XcvCFBP7112P_10295	COG0840	transmembrane signaling receptor activity
XcvCFBP7112P_10305	COG0840	transmembrane signaling receptor activity
XcvCFBP7112P_10315	COG0840	transmembrane signaling receptor activity
XcvCFBP7112P_10320	COG0840	transmembrane signaling receptor activity
XcvCFBP7112P_10325	COG0840	transmembrane signaling receptor activity
XcvCFBP7112P_10340	COG0840	transmembrane signaling receptor activity
XcvCFBP7112P_10345	COG0840	transmembrane signaling receptor activity
XcvCFBP7112P_10365	COG0745	RESPONSE REGULATOR receiver
XcvCFBP7112P_10375	COG0835	chemotaxis
XcvCFBP7112P_10380	COG1192	Involved in chromosome partitioning
XcvCFBP7112P_10385	COG1360	Flagellar Motor Protein
XcvCFBP7112P_10390	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
XcvCFBP7112P_10465	COG0643	Histidine kinase
XcvCFBP7112P_10465	COG2198	Histidine kinase
XcvCFBP7112P_10485	COG0455	bacterial-type flagellum organization
XcvCFBP7112P_10510	COG5001	Diguanylate cyclase
XcvCFBP7112P_10510	COG3300	MHYT domain
XcvCFBP7112P_10520	COG5001	Diguanylate cyclase
XcvCFBP7112P_10520	COG3300	MHYT domain
XcvCFBP7112P_10525	COG1684	flagellar biosynthetic protein fliR
XcvCFBP7112P_10530	COG1987	bacterial-type flagellum assembly
XcvCFBP7112P_10540	COG3190	flagellar
XcvCFBP7112P_10590	COG1677	Flagellar hook-basal body complex protein FliE
XcvCFBP7112P_10630	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7112P_10635	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7112P_10640	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XcvCFBP7112P_10655	COG2204	response regulator
XcvCFBP7112P_10660	COG2201	protein-glutamate methylesterase activity
XcvCFBP7112P_10690	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
XcvCFBP7112P_10695	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XcvCFBP7112P_10700	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XcvCFBP7112P_10710	COG3951	Flagellar rod assembly protein muramidase FlgJ
XcvCFBP7112P_10710	COG1705	Flagellar rod assembly protein muramidase FlgJ
XcvCFBP7112P_10715	COG1706	bacterial-type flagellum-dependent cell motility
XcvCFBP7112P_10720	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
XcvCFBP7112P_10725	COG4786	Flagellar basal body rod
XcvCFBP7112P_10735	COG4787	bacterial-type flagellum-dependent cell motility
XcvCFBP7112P_10740	COG1749	Flagellar hook protein flgE
XcvCFBP7112P_10745	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
XcvCFBP7112P_10750	COG1558	bacterial-type flagellum-dependent cell motility
XcvCFBP7112P_10760	COG0835	chemotaxis
XcvCFBP7112P_10760	COG0784	Response regulator, receiver
XcvCFBP7112P_10780	COG5002	protein histidine kinase activity
XcvCFBP7112P_10810	COG2915	High frequency lysogenization protein hflD homolog
XcvCFBP7112P_10815	COG0482	sulfurtransferase activity
XcvCFBP7112P_10825	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
XcvCFBP7112P_10830	COG0542	response to heat
XcvCFBP7112P_10835	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
XcvCFBP7112P_10840	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
XcvCFBP7112P_10850	COG0492	ferredoxin-NADP+ reductase activity
XcvCFBP7112P_10855	COG1674	ftsk spoiiie
XcvCFBP7112P_10865	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
XcvCFBP7112P_10875	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
XcvCFBP7112P_10880	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
XcvCFBP7112P_10890	COG0183	Belongs to the thiolase family
XcvCFBP7112P_10895	COG1250	3-hydroxyacyl-CoA dehydrogenase
XcvCFBP7112P_10895	COG1024	Enoyl-CoA hydratase
XcvCFBP7112P_10905	COG0105	UTP biosynthetic process
XcvCFBP7112P_10910	COG0820	rRNA (adenine-C2-)-methyltransferase activity
XcvCFBP7112P_10920	COG1426	Protein conserved in bacteria
XcvCFBP7112P_10930	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XcvCFBP7112P_10935	COG1160	GTP binding
XcvCFBP7112P_10940	COG0303	'Molybdopterin
XcvCFBP7112P_10945	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XcvCFBP7112P_10985	COG0708	Exodeoxyribonuclease III
XcvCFBP7112P_10995	COG0303	'Molybdopterin
XcvCFBP7112P_11000	COG0746	molybdenum cofactor guanylyltransferase activity
XcvCFBP7112P_11020	COG2072	flavoprotein involved in K transport
XcvCFBP7112P_11030	COG1914	H( )-stimulated, divalent metal cation uptake system
XcvCFBP7112P_11035	COG1321	iron dependent repressor
XcvCFBP7112P_11040	COG0590	tRNA wobble adenosine to inosine editing
XcvCFBP7112P_11045	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
XcvCFBP7112P_11050	COG0668	transmembrane transport
XcvCFBP7112P_11060	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
XcvCFBP7112P_11075	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7112P_11080	COG1183	phosphatidylcholine synthase activity
XcvCFBP7112P_11090	COG3243	poly(R)-hydroxyalkanoic acid synthase
XcvCFBP7112P_11105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XcvCFBP7112P_11105	COG0723	plastoquinol--plastocyanin reductase activity
XcvCFBP7112P_11115	COG2183	response to ionizing radiation
XcvCFBP7112P_11120	COG0784	Response regulator, receiver
XcvCFBP7112P_11120	COG2205	protein histidine kinase activity
XcvCFBP7112P_11185	COG0800	Aldolase
XcvCFBP7112P_11190	COG0129	dihydroxy-acid dehydratase activity
XcvCFBP7112P_11195	COG0363	glucosamine-6-phosphate deaminase activity
XcvCFBP7112P_11200	COG0837	glucose binding
XcvCFBP7112P_11205	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XcvCFBP7112P_11215	COG0354	folic acid binding
XcvCFBP7112P_11230	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
XcvCFBP7112P_11245	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
XcvCFBP7112P_11250	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
XcvCFBP7112P_11260	COG4591	ABC-type transport system involved in lipoprotein release permease component
XcvCFBP7112P_11265	COG1136	(ABC) transporter
XcvCFBP7112P_11280	COG0811	peptide transport
XcvCFBP7112P_11285	COG0848	biopolymer transport protein
XcvCFBP7112P_11290	COG1132	(ABC) transporter
XcvCFBP7112P_11295	COG1663	tetraacyldisaccharide 4'-kinase activity
XcvCFBP7112P_11300	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
XcvCFBP7112P_11305	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
XcvCFBP7112P_11315	COG0322	excinuclease ABC activity
XcvCFBP7112P_11320	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XcvCFBP7112P_11345	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
XcvCFBP7112P_11375	COG1530	ribonuclease E activity
XcvCFBP7112P_11385	COG3064	Membrane
XcvCFBP7112P_11390	COG0428	transporter
XcvCFBP7112P_11400	COG2154	pterin-4-alpha-carbinolamine dehydratase
XcvCFBP7112P_11405	COG0316	Belongs to the HesB IscA family
XcvCFBP7112P_11405	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
XcvCFBP7112P_11435	COG1073	alpha beta
XcvCFBP7112P_11435	COG2226	methyltransferase
XcvCFBP7112P_11440	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
XcvCFBP7112P_11495	COG3318	Belongs to the UPF0149 family
XcvCFBP7112P_11495	COG3012	SEC-C Motif Domain Protein
XcvCFBP7112P_11515	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XcvCFBP7112P_11635	COG2133	pyrroloquinoline quinone binding
XcvCFBP7112P_11640	COG1408	metallophosphoesterase
XcvCFBP7112P_11645	COG0300	oxidoreductase activity
XcvCFBP7112P_11650	COG0583	DNA-binding transcription factor activity
XcvCFBP7112P_11660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcvCFBP7112P_11665	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcvCFBP7112P_11670	COG1538	Outer membrane efflux protein
XcvCFBP7112P_11680	COG0300	oxidoreductase activity
XcvCFBP7112P_11685	COG2814	Major facilitator Superfamily
XcvCFBP7112P_11695	COG0583	DNA-binding transcription factor activity
XcvCFBP7112P_11705	COG4221	oxidoreductase activity
XcvCFBP7112P_11710	COG0300	oxidoreductase activity
XcvCFBP7112P_11740	COG1136	(ABC) transporter
XcvCFBP7112P_11745	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XcvCFBP7112P_11750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XcvCFBP7112P_11750	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7112P_11750	COG3321	synthase
XcvCFBP7112P_11750	COG4221	oxidoreductase activity
XcvCFBP7112P_11785	COG3220	belongs to the UPF0276 family
XcvCFBP7112P_11805	COG3920	Histidine kinase
XcvCFBP7112P_11815	COG1238	metal cluster binding
XcvCFBP7112P_11845	COG3279	Response regulator of the LytR AlgR family
XcvCFBP7112P_11850	COG3275	phosphorelay sensor kinase activity
XcvCFBP7112P_11890	COG4566	intracellular signal transduction
XcvCFBP7112P_11900	COG5001	Diguanylate cyclase
XcvCFBP7112P_11920	COG3685	Protein conserved in bacteria
XcvCFBP7112P_11945	COG1648	precorrin-2 dehydrogenase activity
XcvCFBP7112P_11945	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XcvCFBP7112P_11960	COG2814	Major facilitator Superfamily
XcvCFBP7112P_11975	COG1335	isochorismatase
XcvCFBP7112P_11990	COG2197	response regulator
XcvCFBP7112P_12005	COG0583	DNA-binding transcription factor activity
XcvCFBP7112P_12010	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XcvCFBP7112P_12015	COG3002	Belongs to the UPF0753 family
XcvCFBP7112P_12020	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XcvCFBP7112P_12020	COG0519	Catalyzes the synthesis of GMP from XMP
XcvCFBP7112P_12030	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
XcvCFBP7112P_12045	COG0475	glutathione-regulated potassium exporter activity
XcvCFBP7112P_12045	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XcvCFBP7112P_12050	COG1210	Utp--glucose-1-phosphate uridylyltransferase
XcvCFBP7112P_12060	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XcvCFBP7112P_12065	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
XcvCFBP7112P_12075	COG0776	regulation of translation
XcvCFBP7112P_12080	COG0539	negative regulation of cytoplasmic translation
XcvCFBP7112P_12085	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
XcvCFBP7112P_12090	COG0257	Belongs to the bacterial ribosomal protein bL36 family
XcvCFBP7112P_12100	COG2957	Belongs to the agmatine deiminase family
XcvCFBP7112P_12105	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XcvCFBP7112P_12130	COG0395	ABC-type sugar transport system, permease component
XcvCFBP7112P_12135	COG1175	transmembrane transport
XcvCFBP7112P_12165	COG2350	Protein conserved in bacteria
XcvCFBP7112P_12170	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
XcvCFBP7112P_12175	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
XcvCFBP7112P_12180	COG1187	pseudouridine synthase activity
XcvCFBP7112P_12195	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XcvCFBP7112P_12200	COG0436	Aminotransferase
XcvCFBP7112P_12205	COG4133	protoheme IX ABC transporter activity
XcvCFBP7112P_12225	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
XcvCFBP7112P_12230	COG1138	Cytochrome C-type biogenesis protein
XcvCFBP7112P_12250	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XcvCFBP7112P_12255	COG1278	Cold shock
XcvCFBP7112P_12260	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
XcvCFBP7112P_12265	COG4988	ABC transporter
XcvCFBP7112P_12275	COG1294	oxidase, subunit
XcvCFBP7112P_12305	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
XcvCFBP7112P_12310	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
XcvCFBP7112P_12320	COG0165	Argininosuccinate lyase
XcvCFBP7112P_12325	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
XcvCFBP7112P_12335	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XcvCFBP7112P_12350	COG0137	argininosuccinate synthase activity
XcvCFBP7112P_12355	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
XcvCFBP7112P_12365	COG0215	cysteine-tRNA ligase activity
XcvCFBP7112P_12370	COG2166	iron-sulfur cluster assembly
XcvCFBP7112P_12380	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XcvCFBP7112P_12385	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
XcvCFBP7112P_12390	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XcvCFBP7112P_12410	COG4302	ethanolamine ammonia-lyase activity
XcvCFBP7112P_12460	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XcvCFBP7112P_12465	COG0402	S-adenosylhomocysteine deaminase activity
XcvCFBP7112P_12475	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XcvCFBP7112P_12480	COG1509	lysine 2,3-aminomutase activity
XcvCFBP7112P_12485	COG5001	Diguanylate cyclase
XcvCFBP7112P_12485	COG3300	MHYT domain
XcvCFBP7112P_12500	COG0483	inositol monophosphate 1-phosphatase activity
XcvCFBP7112P_12530	COG0513	Belongs to the DEAD box helicase family
XcvCFBP7112P_12535	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
XcvCFBP7112P_12540	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
XcvCFBP7112P_12550	COG0625	glutathione transferase activity
XcvCFBP7112P_12560	COG4681	YaeQ
XcvCFBP7112P_12565	COG2081	HI0933 family
XcvCFBP7112P_12575	COG0501	Belongs to the peptidase M48B family
XcvCFBP7112P_12580	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XcvCFBP7112P_12585	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7112P_12610	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
XcvCFBP7112P_12615	COG0860	N-Acetylmuramoyl-L-alanine amidase
XcvCFBP7112P_12620	COG0802	atpase or kinase
XcvCFBP7112P_12625	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XcvCFBP7112P_12625	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
XcvCFBP7112P_12630	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XcvCFBP7112P_12635	COG1570	exodeoxyribonuclease VII activity
XcvCFBP7112P_12645	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XcvCFBP7112P_12690	COG0835	chemotaxis
XcvCFBP7112P_12695	COG0840	transmembrane signaling receptor activity
XcvCFBP7112P_12700	COG2094	Belongs to the DNA glycosylase MPG family
XcvCFBP7112P_12705	COG1201	RNA secondary structure unwinding
XcvCFBP7112P_12725	COG2969	positive regulation of protein catabolic process
XcvCFBP7112P_12730	COG0625	glutathione transferase activity
XcvCFBP7112P_12735	COG2857	Cytochrome c1
XcvCFBP7112P_12740	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
XcvCFBP7112P_12745	COG0723	plastoquinol--plastocyanin reductase activity
XcvCFBP7112P_12755	COG0741	lytic transglycosylase activity
XcvCFBP7112P_12770	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XcvCFBP7112P_12775	COG1702	phosphate starvation-inducible protein PhoH
XcvCFBP7112P_12785	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
XcvCFBP7112P_12795	COG4535	Mg2 and Co2 transporter CorC
XcvCFBP7112P_12810	COG1012	belongs to the aldehyde dehydrogenase family
XcvCFBP7112P_12815	COG1177	transmembrane transport
XcvCFBP7112P_12820	COG1176	ABC-type spermidine putrescine transport system, permease component I
XcvCFBP7112P_12830	COG3842	ATPase activity
XcvCFBP7112P_12850	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
XcvCFBP7112P_12865	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
XcvCFBP7112P_12870	COG0174	glutamine synthetase
XcvCFBP7112P_12875	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XcvCFBP7112P_12880	COG0745	RESPONSE REGULATOR receiver
XcvCFBP7112P_12880	COG3706	GGDEF domain
XcvCFBP7112P_12885	COG2703	oxygen carrier activity
XcvCFBP7112P_12890	COG0477	Major facilitator Superfamily
XcvCFBP7112P_12900	COG0243	molybdopterin cofactor binding
XcvCFBP7112P_12905	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
XcvCFBP7112P_12935	COG2733	membrane
XcvCFBP7112P_12940	COG5002	protein histidine kinase activity
XcvCFBP7112P_12940	COG2205	protein histidine kinase activity
XcvCFBP7112P_12940	COG0784	Response regulator, receiver
XcvCFBP7112P_12960	COG0477	Major facilitator Superfamily
XcvCFBP7112P_12965	COG2902	Dehydrogenase
XcvCFBP7112P_12975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcvCFBP7112P_12980	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcvCFBP7112P_12985	COG1609	Transcriptional regulator
XcvCFBP7112P_12990	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XcvCFBP7112P_12990	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
XcvCFBP7112P_12995	COG1105	Belongs to the carbohydrate kinase PfkB family
XcvCFBP7112P_13000	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XcvCFBP7112P_13000	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XcvCFBP7112P_13020	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XcvCFBP7112P_13030	COG1862	Preprotein translocase
XcvCFBP7112P_13035	COG0343	queuine tRNA-ribosyltransferase activity
XcvCFBP7112P_13040	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
XcvCFBP7112P_13075	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
XcvCFBP7112P_13080	COG3291	Pkd domain containing protein
XcvCFBP7112P_13085	COG0405	Gamma-glutamyltransferase
XcvCFBP7112P_13090	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XcvCFBP7112P_13105	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
XcvCFBP7112P_13110	COG0742	ribosomal rna small subunit methyltransferase
XcvCFBP7112P_13115	COG0326	Molecular chaperone. Has ATPase activity
XcvCFBP7112P_13205	COG0531	amino acid
XcvCFBP7112P_13220	COG0006	proline dipeptidase activity
XcvCFBP7112P_13230	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XcvCFBP7112P_13245	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XcvCFBP7112P_13250	COG3938	Belongs to the proline racemase family
XcvCFBP7112P_13260	COG0552	protein localization to endoplasmic reticulum
XcvCFBP7112P_13265	COG1194	a g-specific adenine glycosylase
XcvCFBP7112P_13270	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
XcvCFBP7112P_13275	COG0784	Response regulator, receiver
XcvCFBP7112P_13275	COG4191	Histidine kinase
XcvCFBP7112P_13290	COG0322	excinuclease ABC activity
XcvCFBP7112P_13305	COG3040	lipid binding
XcvCFBP7112P_13315	COG1960	acyl-CoA dehydrogenase activity
XcvCFBP7112P_13325	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
XcvCFBP7112P_13345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XcvCFBP7112P_13350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XcvCFBP7112P_13355	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XcvCFBP7112P_13390	COG0438	transferase activity, transferring glycosyl groups
XcvCFBP7112P_13395	COG0438	transferase activity, transferring glycosyl groups
XcvCFBP7112P_13440	COG0776	regulation of translation
XcvCFBP7112P_13445	COG0072	phenylalanine-tRNA ligase activity
XcvCFBP7112P_13445	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XcvCFBP7112P_13450	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
XcvCFBP7112P_13455	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
XcvCFBP7112P_13460	COG0291	Belongs to the bacterial ribosomal protein bL35 family
XcvCFBP7112P_13465	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
XcvCFBP7112P_13470	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
XcvCFBP7112P_13495	COG1082	Xylose isomerase domain protein TIM barrel
XcvCFBP7112P_13545	COG3702	type iv secretory pathway
XcvCFBP7112P_13565	COG2948	multi-organism process
XcvCFBP7112P_13585	COG3505	Type IV secretory pathway VirD4
XcvCFBP7112P_13600	COG0556	nucleotide-excision repair
XcvCFBP7112P_13670	COG3275	phosphorelay sensor kinase activity
XcvCFBP7112P_13675	COG1611	Belongs to the LOG family
XcvCFBP7112P_13690	COG2095	MarC family integral membrane protein
XcvCFBP7112P_13700	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XcvCFBP7112P_13705	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XcvCFBP7112P_13735	COG1185	polyribonucleotide nucleotidyltransferase activity
XcvCFBP7112P_13740	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
XcvCFBP7112P_13745	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
XcvCFBP7112P_13750	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
XcvCFBP7112P_13755	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
XcvCFBP7112P_13760	COG0195	Participates in both transcription termination and antitermination
XcvCFBP7112P_13765	COG0779	Required for maturation of 30S ribosomal subunits
XcvCFBP7112P_13775	COG1007	ATP synthesis coupled electron transport
XcvCFBP7112P_13790	COG0713	ATP synthesis coupled electron transport
XcvCFBP7112P_13800	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XcvCFBP7112P_13805	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
XcvCFBP7112P_13815	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XcvCFBP7112P_13820	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
XcvCFBP7112P_13825	COG0649	NAD binding
XcvCFBP7112P_13830	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XcvCFBP7112P_13835	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XcvCFBP7112P_13840	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XcvCFBP7112P_13855	COG0149	triose-phosphate isomerase activity
XcvCFBP7112P_13860	COG0300	oxidoreductase activity
XcvCFBP7112P_13890	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XcvCFBP7112P_13895	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
XcvCFBP7112P_13900	COG0159	tryptophan synthase activity
XcvCFBP7112P_13910	COG0133	tryptophan synthase activity
XcvCFBP7112P_13920	COG0135	phosphoribosylanthranilate isomerase activity
XcvCFBP7112P_13925	COG0101	tRNA pseudouridine synthase activity
XcvCFBP7112P_13940	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XcvCFBP7112P_13945	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XcvCFBP7112P_13950	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
XcvCFBP7112P_13955	COG2890	protein-(glutamine-N5) methyltransferase activity
XcvCFBP7112P_13965	COG0688	phosphatidylethanolamine metabolic process
XcvCFBP7112P_13980	COG0433	COG0433 Predicted ATPase
XcvCFBP7112P_13985	COG0494	nUDIX hydrolase
XcvCFBP7112P_14005	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XcvCFBP7112P_14010	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XcvCFBP7112P_14035	COG0717	Belongs to the dCTP deaminase family
XcvCFBP7112P_14045	COG0489	protein tyrosine kinase activity
XcvCFBP7112P_14065	COG3590	peptidase
XcvCFBP7112P_14070	COG3590	peptidase
XcvCFBP7112P_14090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XcvCFBP7112P_14095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XcvCFBP7112P_14100	COG2311	Membrane
XcvCFBP7112P_14105	COG1047	Peptidyl-prolyl cis-trans
XcvCFBP7112P_14110	COG0791	NLP P60 protein
XcvCFBP7112P_14115	COG0791	NLP P60 protein
XcvCFBP7112P_14125	COG4106	trans-aconitate 2-methyltransferase activity
XcvCFBP7112P_14130	COG1301	dicarboxylic acid transport
XcvCFBP7112P_14135	COG1785	Belongs to the alkaline phosphatase family
XcvCFBP7112P_14145	COG0037	tRNA processing
XcvCFBP7112P_14150	COG1722	exodeoxyribonuclease VII activity
XcvCFBP7112P_14155	COG0142	geranyltranstransferase activity
XcvCFBP7112P_14170	COG0312	modulator of DNA gyrase
XcvCFBP7112P_14175	COG3028	Belongs to the UPF0307 family
XcvCFBP7112P_14180	COG0312	modulator of DNA gyrase
XcvCFBP7112P_14190	COG3164	Protein of unknown function
XcvCFBP7112P_14195	COG1530	ribonuclease E activity
XcvCFBP7112P_14200	COG0424	maF-like protein
XcvCFBP7112P_14205	COG2968	Membrane
XcvCFBP7112P_14220	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
XcvCFBP7112P_14235	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
XcvCFBP7112P_14250	COG0495	leucyl-tRNA aminoacylation
XcvCFBP7112P_14260	COG3118	belongs to the thioredoxin family
XcvCFBP7112P_14295	COG2155	Conserved Protein
XcvCFBP7112P_14300	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XcvCFBP7112P_14340	COG1132	(ABC) transporter
XcvCFBP7112P_14365	COG1538	Outer membrane efflux protein
XcvCFBP7112P_14370	COG0745	RESPONSE REGULATOR receiver
XcvCFBP7112P_14375	COG5002	protein histidine kinase activity
XcvCFBP7112P_14375	COG5000	phosphorelay sensor kinase activity
XcvCFBP7112P_14380	COG0475	glutathione-regulated potassium exporter activity
XcvCFBP7112P_14385	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
XcvCFBP7112P_14390	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XcvCFBP7112P_14410	COG0745	RESPONSE REGULATOR receiver
XcvCFBP7112P_14410	COG3706	GGDEF domain
XcvCFBP7112P_14415	COG1187	pseudouridine synthase activity
XcvCFBP7112P_14420	COG5002	protein histidine kinase activity
XcvCFBP7112P_14420	COG5001	Diguanylate cyclase
XcvCFBP7112P_14430	COG1595	DNA-templated transcription, initiation
XcvCFBP7112P_14540	COG0667	Aldo Keto reductase
XcvCFBP7112P_14550	COG0583	DNA-binding transcription factor activity
XcvCFBP7112P_14560	COG2207	Transcriptional regulator
XcvCFBP7112P_14570	COG1309	transcriptional regulator
XcvCFBP7112P_14575	COG1538	Outer membrane efflux protein
XcvCFBP7112P_14580	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcvCFBP7112P_14595	COG0735	belongs to the Fur family
XcvCFBP7112P_14600	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XcvCFBP7112P_14625	COG4452	Inner membrane protein CreD
XcvCFBP7112P_14635	COG2205	protein histidine kinase activity
XcvCFBP7112P_14640	COG0745	RESPONSE REGULATOR receiver
XcvCFBP7112P_14645	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
XcvCFBP7112P_14660	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
XcvCFBP7112P_14710	COG0643	Histidine kinase
XcvCFBP7112P_14710	COG2198	Histidine kinase
XcvCFBP7112P_14715	COG0840	transmembrane signaling receptor activity
XcvCFBP7112P_14720	COG0835	chemotaxis
XcvCFBP7112P_14725	COG2199	diguanylate cyclase activity
XcvCFBP7112P_14725	COG2200	EAL domain
XcvCFBP7112P_14725	COG2202	Pas domain
XcvCFBP7112P_14730	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XcvCFBP7112P_14735	COG2201	protein-glutamate methylesterase activity
XcvCFBP7112P_14740	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XcvCFBP7112P_14745	COG3590	peptidase
XcvCFBP7112P_14755	COG0588	phosphoglycerate mutase activity
XcvCFBP7112P_14760	COG1515	deoxyribonuclease V activity
XcvCFBP7112P_14770	COG1741	Belongs to the pirin family
XcvCFBP7112P_14785	COG1741	Belongs to the pirin family
XcvCFBP7112P_14790	COG1966	Carbon starvation protein
XcvCFBP7112P_14795	COG2879	small protein
XcvCFBP7112P_14845	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
XcvCFBP7112P_14850	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XcvCFBP7112P_14855	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XcvCFBP7112P_14860	COG2080	2 iron, 2 sulfur cluster binding
XcvCFBP7112P_14865	COG3321	synthase
XcvCFBP7112P_14865	COG0604	alcohol dehydrogenase
XcvCFBP7112P_14865	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7112P_14870	COG3706	GGDEF domain
XcvCFBP7112P_14870	COG5001	Diguanylate cyclase
XcvCFBP7112P_14870	COG2203	Gaf domain
XcvCFBP7112P_14870	COG4251	negative regulation of phosphorylation
XcvCFBP7112P_14875	COG0629	single-stranded DNA binding
XcvCFBP7112P_14880	COG0142	geranyltranstransferase activity
XcvCFBP7112P_14895	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
XcvCFBP7112P_14910	COG0527	aspartate kinase activity
XcvCFBP7112P_14915	COG0384	phenazine biosynthesis protein PhzF
XcvCFBP7112P_14920	COG0384	phenazine biosynthesis protein PhzF
XcvCFBP7112P_14930	COG1764	response to oxidative stress
XcvCFBP7112P_14935	COG0540	Belongs to the ATCase OTCase family
XcvCFBP7112P_14940	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
XcvCFBP7112P_14945	COG1678	Uncharacterized ACR, COG1678
XcvCFBP7112P_14955	COG0519	Catalyzes the synthesis of GMP from XMP
XcvCFBP7112P_14980	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
XcvCFBP7112P_14995	COG0739	heme binding
XcvCFBP7112P_15015	COG0693	protein deglycase activity
XcvCFBP7112P_15025	COG1959	2 iron, 2 sulfur cluster binding
XcvCFBP7112P_15030	COG0719	Fe-S assembly protein
XcvCFBP7112P_15035	COG0396	ATPase activity
XcvCFBP7112P_15040	COG0719	Fe-S assembly protein
XcvCFBP7112P_15045	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XcvCFBP7112P_15065	COG3128	pkhd-type hydroxylase
XcvCFBP7112P_15090	COG1477	protein flavinylation
XcvCFBP7112P_15095	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XcvCFBP7112P_15105	COG1555	photosystem II stabilization
XcvCFBP7112P_15120	COG3178	'Phosphotransferase
XcvCFBP7112P_15125	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XcvCFBP7112P_15140	COG0628	permease
XcvCFBP7112P_15150	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
XcvCFBP7112P_15160	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
XcvCFBP7112P_15180	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
XcvCFBP7112P_15185	COG0271	Belongs to the BolA IbaG family
XcvCFBP7112P_15195	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
XcvCFBP7112P_15205	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
XcvCFBP7112P_15210	COG1137	ATPase activity
XcvCFBP7112P_15225	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
XcvCFBP7112P_15230	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
XcvCFBP7112P_15235	COG1660	Displays ATPase and GTPase activities
XcvCFBP7112P_15245	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XcvCFBP7112P_15250	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XcvCFBP7112P_15255	COG2239	Acts as a magnesium transporter
XcvCFBP7112P_15265	COG1294	oxidase, subunit
XcvCFBP7112P_15270	COG1271	oxidase subunit
XcvCFBP7112P_15280	COG1113	amino acid transport
XcvCFBP7112P_15310	COG2197	response regulator
XcvCFBP7112P_15315	COG0531	amino acid
XcvCFBP7112P_15410	COG2814	Major facilitator Superfamily
XcvCFBP7112P_15425	COG0754	glutathionylspermidine amidase activity
XcvCFBP7112P_15450	COG1842	Phage shock protein A
XcvCFBP7112P_15460	COG0259	pyridoxamine-phosphate oxidase activity
XcvCFBP7112P_15465	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
XcvCFBP7112P_15470	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
XcvCFBP7112P_15480	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
XcvCFBP7112P_15485	COG0477	Major facilitator Superfamily
XcvCFBP7112P_15500	COG0745	RESPONSE REGULATOR receiver
XcvCFBP7112P_15510	COG2205	protein histidine kinase activity
XcvCFBP7112P_15510	COG2198	Histidine kinase
XcvCFBP7112P_15510	COG0784	Response regulator, receiver
XcvCFBP7112P_15515	COG2353	YceI-like domain
XcvCFBP7112P_15535	COG1760	l-serine dehydratase
XcvCFBP7112P_15550	COG0460	homoserine dehydrogenase
XcvCFBP7112P_15550	COG0527	aspartate kinase activity
XcvCFBP7112P_15555	COG0626	cystathionine gamma-synthase activity
XcvCFBP7112P_15560	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XcvCFBP7112P_15565	COG0739	heme binding
XcvCFBP7112P_15570	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
XcvCFBP7112P_15575	COG1272	protein, Hemolysin III
XcvCFBP7112P_15580	COG2982	Protein involved in outer membrane biogenesis
XcvCFBP7112P_15585	COG0516	GMP reductase activity
XcvCFBP7112P_15585	COG0517	IMP dehydrogenase activity
XcvCFBP7112P_15590	COG0463	Glycosyl transferase, family 2
XcvCFBP7112P_15595	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XcvCFBP7112P_15600	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
XcvCFBP7112P_15610	COG4771	TonB-dependent receptor
XcvCFBP7112P_15620	COG1309	transcriptional regulator
XcvCFBP7112P_15625	COG2267	carboxylic ester hydrolase activity
XcvCFBP7112P_15630	COG1960	acyl-CoA dehydrogenase activity
XcvCFBP7112P_15660	COG0509	glycine decarboxylation via glycine cleavage system
XcvCFBP7112P_15665	COG0404	The glycine cleavage system catalyzes the degradation of glycine
XcvCFBP7112P_15680	COG1742	UPF0060 membrane protein
XcvCFBP7112P_15685	COG3956	TIGRFAM MazG family protein
XcvCFBP7112P_15690	COG1218	3'(2'),5'-bisphosphate nucleotidase
XcvCFBP7112P_15695	COG0494	nUDIX hydrolase
XcvCFBP7112P_15705	COG1385	rRNA (uridine-N3-)-methyltransferase activity
XcvCFBP7112P_15710	COG0837	glucose binding
XcvCFBP7112P_15725	COG1388	LysM domain
XcvCFBP7112P_15725	COG3858	chitin binding
XcvCFBP7112P_15740	COG1472	Belongs to the glycosyl hydrolase 3 family
XcvCFBP7112P_15755	COG0531	amino acid
XcvCFBP7112P_15765	COG1486	melibiose metabolic process
XcvCFBP7112P_15775	COG3537	Alpha-1,2-mannosidase
XcvCFBP7112P_15815	COG3142	Participates in the control of copper homeostasis
XcvCFBP7112P_15820	COG1446	asparaginase
XcvCFBP7112P_15850	COG0840	transmembrane signaling receptor activity
XcvCFBP7112P_15855	COG0835	chemotaxis
XcvCFBP7112P_15870	COG0189	ligase activity
XcvCFBP7112P_15880	COG1397	ADP-ribosylglycohydrolase
XcvCFBP7112P_15890	COG1199	ATP-dependent helicase activity
XcvCFBP7112P_15900	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XcvCFBP7112P_15905	COG1442	glycosyl transferase family 8
XcvCFBP7112P_15905	COG1216	Glycosyl transferase, family 2
XcvCFBP7112P_15920	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XcvCFBP7112P_15930	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
XcvCFBP7112P_15935	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
XcvCFBP7112P_15940	COG0535	radical SAM domain protein
XcvCFBP7112P_15945	COG0535	radical SAM domain protein
XcvCFBP7112P_15960	COG0837	glucose binding
XcvCFBP7112P_15975	COG1643	Atp-dependent helicase
XcvCFBP7112P_15980	COG0783	Belongs to the Dps family
XcvCFBP7112P_15985	COG0514	ATP-dependent DNA helicase (RecQ)
XcvCFBP7112P_16030	COG0840	transmembrane signaling receptor activity
XcvCFBP7112P_16050	COG3920	Histidine kinase
XcvCFBP7112P_16065	COG0602	queuosine metabolic process
XcvCFBP7112P_16075	COG2885	chlorophyll binding
XcvCFBP7112P_16080	COG0823	Involved in the tonB-independent uptake of proteins
XcvCFBP7112P_16090	COG0848	biopolymer transport protein
XcvCFBP7112P_16100	COG0824	Thioesterase
XcvCFBP7112P_16105	COG2255	four-way junction helicase activity
XcvCFBP7112P_16110	COG3158	transport of potassium into the cell
XcvCFBP7112P_16115	COG0632	four-way junction helicase activity
XcvCFBP7112P_16120	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
XcvCFBP7112P_16125	COG0217	transcriptional regulatory protein
XcvCFBP7112P_16140	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
XcvCFBP7112P_16155	COG0477	Major facilitator Superfamily
XcvCFBP7112P_16195	COG0488	(ABC) transporter
XcvCFBP7112P_16235	COG4651	solute:proton antiporter activity
XcvCFBP7112P_16235	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XcvCFBP7112P_16245	COG4772	TonB-dependent receptor
XcvCFBP7112P_16255	COG4264	IucA IucC family
XcvCFBP7112P_16270	COG0019	diaminopimelate decarboxylase activity
XcvCFBP7112P_16295	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
XcvCFBP7112P_16305	COG1492	cobalamin metabolic process
XcvCFBP7112P_16315	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XcvCFBP7112P_16340	COG4206	TonB-dependent receptor
XcvCFBP7112P_16345	COG0542	response to heat
XcvCFBP7112P_16350	COG1116	anion transmembrane transporter activity
XcvCFBP7112P_16355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XcvCFBP7112P_16360	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XcvCFBP7112P_16365	COG0667	Aldo Keto reductase
XcvCFBP7112P_16375	COG4771	TonB-dependent receptor
XcvCFBP7112P_16380	COG2827	Endonuclease containing a URI domain
XcvCFBP7112P_16420	COG1877	trehalose-phosphatase activity
XcvCFBP7112P_16425	COG3387	PFAM Glycoside hydrolase 15-related
XcvCFBP7112P_16445	COG0840	transmembrane signaling receptor activity
XcvCFBP7112P_16450	COG3011	Protein conserved in bacteria
XcvCFBP7112P_16465	COG0564	pseudouridine synthase activity
XcvCFBP7112P_16470	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XcvCFBP7112P_16480	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XcvCFBP7112P_16480	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
XcvCFBP7112P_16495	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
XcvCFBP7112P_16500	COG0045	succinate-CoA ligase (ADP-forming) activity
XcvCFBP7112P_16540	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
XcvCFBP7112P_16545	COG0237	dephospho-CoA kinase activity
XcvCFBP7112P_16555	COG0745	RESPONSE REGULATOR receiver
XcvCFBP7112P_16565	COG0189	ligase activity
XcvCFBP7112P_16625	COG3209	COG3209 Rhs family protein
XcvCFBP7112P_16670	COG2022	thiamine diphosphate biosynthetic process
XcvCFBP7112P_16675	COG0220	tRNA (guanine-N7-)-methyltransferase activity
XcvCFBP7112P_16680	COG0471	metal ion transport
XcvCFBP7112P_16680	COG3273	potassium ion transport
XcvCFBP7112P_16705	COG1970	mechanosensitive ion channel activity
XcvCFBP7112P_16715	COG1609	Transcriptional regulator
XcvCFBP7112P_16725	COG3250	beta-galactosidase activity
XcvCFBP7112P_16730	COG4948	Mandelate Racemase Muconate Lactonizing
XcvCFBP7112P_16740	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XcvCFBP7112P_16750	COG0308	aminopeptidase N
XcvCFBP7112P_16755	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcvCFBP7112P_16765	COG2895	sulfate adenylyltransferase (ATP) activity
XcvCFBP7112P_16765	COG0529	Catalyzes the synthesis of activated sulfate
XcvCFBP7112P_16770	COG0175	sulfate reduction
XcvCFBP7112P_16775	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XcvCFBP7112P_16780	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XcvCFBP7112P_16785	COG0175	sulfate reduction
XcvCFBP7112P_16825	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XcvCFBP7112P_16825	COG1648	precorrin-2 dehydrogenase activity
XcvCFBP7112P_16840	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
XcvCFBP7112P_16845	COG3588	fructose-bisphosphate aldolase
XcvCFBP7112P_16860	COG0469	pyruvate kinase activity
XcvCFBP7112P_16870	COG0126	phosphoglycerate kinase activity
XcvCFBP7112P_16895	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
XcvCFBP7112P_16905	COG3047	cAMP biosynthetic process
XcvCFBP7112P_16910	COG3047	cAMP biosynthetic process
XcvCFBP7112P_16920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XcvCFBP7112P_16920	COG3453	Protein conserved in bacteria
XcvCFBP7112P_16925	COG0725	ABC transporter, periplasmic molybdate-binding protein
XcvCFBP7112P_16930	COG4149	molybdate abc transporter
XcvCFBP7112P_16935	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
XcvCFBP7112P_16970	COG1376	ErfK ybiS ycfS ynhG family protein
XcvCFBP7112P_16975	COG0739	heme binding
XcvCFBP7112P_16980	COG4773	Receptor
XcvCFBP7112P_16985	COG0596	Alpha beta hydrolase
XcvCFBP7112P_16990	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
XcvCFBP7112P_16995	COG1301	dicarboxylic acid transport
XcvCFBP7112P_17005	COG2304	oxidoreductase activity
XcvCFBP7112P_17025	COG0714	Associated with various cellular activities
XcvCFBP7112P_17055	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XcvCFBP7112P_17070	COG0254	rRNA binding
XcvCFBP7112P_17080	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
XcvCFBP7112P_17090	COG2721	sulfolactate sulfo-lyase activity
XcvCFBP7112P_17105	COG2271	Major facilitator Superfamily
XcvCFBP7112P_17120	COG0583	DNA-binding transcription factor activity
XcvCFBP7112P_17125	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XcvCFBP7112P_17130	COG1758	RNA polymerase activity
XcvCFBP7112P_17140	COG1561	YicC-like family, N-terminal region
XcvCFBP7112P_17145	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
XcvCFBP7112P_17155	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
XcvCFBP7112P_17160	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XcvCFBP7112P_17175	COG0006	proline dipeptidase activity
XcvCFBP7112P_17185	COG0006	proline dipeptidase activity
XcvCFBP7112P_17190	COG3079	Belongs to the UPF0149 family
XcvCFBP7112P_17210	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
XcvCFBP7112P_17220	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
XcvCFBP7112P_17230	COG2912	Transglutaminase-like superfamily
XcvCFBP7112P_17235	COG1773	rubredoxin
XcvCFBP7112P_17240	COG0352	thiamine-phosphate diphosphorylase activity
XcvCFBP7112P_17260	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XcvCFBP7112P_17275	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XcvCFBP7112P_17305	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XcvCFBP7112P_17310	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XcvCFBP7112P_17325	COG0671	phosphoesterase, PA-phosphatase related
XcvCFBP7112P_17330	COG3781	membrane
XcvCFBP7112P_17340	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XcvCFBP7112P_17345	COG0563	adenylate kinase activity
XcvCFBP7112P_17360	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
XcvCFBP7112P_17370	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
XcvCFBP7112P_17390	COG3710	Transcriptional regulator
XcvCFBP7112P_17395	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
XcvCFBP7112P_17410	COG0840	transmembrane signaling receptor activity
XcvCFBP7112P_17415	COG0405	Gamma-glutamyltransferase
XcvCFBP7112P_17420	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
XcvCFBP7112P_17440	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
XcvCFBP7112P_17445	COG0473	3-isopropylmalate dehydrogenase activity
XcvCFBP7112P_17450	COG0066	3-isopropylmalate dehydratase activity
XcvCFBP7112P_17455	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
XcvCFBP7112P_17475	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XcvCFBP7112P_17480	COG1538	Outer membrane efflux protein
XcvCFBP7112P_17485	COG1519	Transferase
XcvCFBP7112P_17495	COG1560	Kdo2-lipid A biosynthetic process
XcvCFBP7112P_17550	COG0280	phosphate acetyltransferase
XcvCFBP7112P_17550	COG0281	malic enzyme
XcvCFBP7112P_17555	COG1301	dicarboxylic acid transport
XcvCFBP7112P_17580	COG0583	DNA-binding transcription factor activity
XcvCFBP7112P_17590	COG0667	Aldo Keto reductase
XcvCFBP7112P_17605	COG2197	response regulator
XcvCFBP7112P_17615	COG1840	ABC-type Fe3 transport system, periplasmic component
XcvCFBP7112P_17620	COG0642	Histidine kinase
XcvCFBP7112P_17640	COG2851	Citrate transporter
XcvCFBP7112P_17645	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7112P_17650	COG1609	Transcriptional regulator
XcvCFBP7112P_17655	COG2211	Major facilitator Superfamily
XcvCFBP7112P_17685	COG1162	GTPase activity
XcvCFBP7112P_17690	COG0436	Aminotransferase
XcvCFBP7112P_17705	COG0726	polysaccharide deacetylase
XcvCFBP7112P_17710	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XcvCFBP7112P_17725	COG3964	amidohydrolase
XcvCFBP7112P_17730	COG0402	S-adenosylhomocysteine deaminase activity
XcvCFBP7112P_17755	COG1307	EDD domain protein, DegV family
XcvCFBP7112P_17760	COG0242	peptide deformylase activity
XcvCFBP7112P_17785	COG0457	Tetratricopeptide repeat
XcvCFBP7112P_17790	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
XcvCFBP7112P_17795	COG1215	transferase activity, transferring glycosyl groups
XcvCFBP7112P_17800	COG1215	transferase activity, transferring glycosyl groups
XcvCFBP7112P_17815	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
XcvCFBP7112P_17870	COG2188	Transcriptional regulator
XcvCFBP7112P_17880	COG1450	Type ii and iii secretion system protein
XcvCFBP7112P_17895	COG3166	PFAM Fimbrial assembly family protein
XcvCFBP7112P_17900	COG3156	type II secretion system protein K
XcvCFBP7112P_17905	COG4795	General secretion pathway protein
XcvCFBP7112P_17910	COG2165	general secretion pathway protein
XcvCFBP7112P_17915	COG4970	Tfp pilus assembly protein FimT
XcvCFBP7112P_17920	COG2165	general secretion pathway protein
XcvCFBP7112P_17925	COG1459	type II secretion system
XcvCFBP7112P_17935	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XcvCFBP7112P_17940	COG1404	Belongs to the peptidase S8 family
XcvCFBP7112P_17945	COG5295	Hep Hag repeat protein
XcvCFBP7112P_17950	COG1404	Belongs to the peptidase S8 family
XcvCFBP7112P_17955	COG5295	Hep Hag repeat protein
XcvCFBP7112P_17960	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XcvCFBP7112P_17960	COG0047	phosphoribosylformylglycinamidine synthase activity
XcvCFBP7112P_17975	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XcvCFBP7112P_17990	COG4974	Belongs to the 'phage' integrase family
XcvCFBP7112P_18005	COG0795	lipopolysaccharide-transporting ATPase activity
XcvCFBP7112P_18015	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XcvCFBP7112P_18030	COG0525	valine-tRNA ligase activity
XcvCFBP7112P_18065	COG1183	phosphatidylcholine synthase activity
XcvCFBP7112P_18075	COG0442	prolyl-tRNA aminoacylation
XcvCFBP7112P_18090	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XcvCFBP7112P_18095	COG1127	ABC transporter
XcvCFBP7112P_18100	COG3218	ABC-type transport auxiliary lipoprotein component
XcvCFBP7112P_18100	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XcvCFBP7112P_18130	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XcvCFBP7112P_18135	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
XcvCFBP7112P_18135	COG0662	Cupin 2, conserved barrel domain protein
XcvCFBP7112P_18165	COG2086	electron transfer activity
XcvCFBP7112P_18180	COG2226	methyltransferase
XcvCFBP7112P_18185	COG0463	Glycosyl transferase, family 2
XcvCFBP7112P_18195	COG0463	Glycosyl transferase, family 2
XcvCFBP7112P_18210	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
XcvCFBP7112P_18235	COG0626	cystathionine gamma-synthase activity
XcvCFBP7112P_18265	COG0625	glutathione transferase activity
XcvCFBP7112P_18280	COG0513	Belongs to the DEAD box helicase family
XcvCFBP7112P_18290	COG4206	TonB-dependent receptor
XcvCFBP7112P_18300	COG0720	synthase
XcvCFBP7112P_18310	COG2015	COG2015, Alkyl sulfatase and related hydrolases
XcvCFBP7112P_18320	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
XcvCFBP7112P_18325	COG1956	GAF domain-containing protein
XcvCFBP7112P_18335	COG2819	hydrolase of the alpha beta superfamily
XcvCFBP7112P_18345	COG0546	phosphoglycolate phosphatase activity
XcvCFBP7112P_18350	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
XcvCFBP7112P_18355	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XcvCFBP7112P_18370	COG0339	signal peptide processing
XcvCFBP7112P_18420	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XcvCFBP7112P_18425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcvCFBP7112P_18430	COG1136	(ABC) transporter
XcvCFBP7112P_18435	COG0577	efflux transmembrane transporter activity
XcvCFBP7112P_18440	COG0577	efflux transmembrane transporter activity
XcvCFBP7112P_18440	COG1136	(ABC) transporter
XcvCFBP7112P_18450	COG2204	response regulator
XcvCFBP7112P_18455	COG4191	Histidine kinase
XcvCFBP7112P_18460	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
XcvCFBP7112P_18480	COG0355	proton-transporting ATP synthase activity, rotational mechanism
XcvCFBP7112P_18485	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
XcvCFBP7112P_18490	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
XcvCFBP7112P_18495	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
XcvCFBP7112P_18500	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
XcvCFBP7112P_18505	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
XcvCFBP7112P_18515	COG0356	it plays a direct role in the translocation of protons across the membrane
XcvCFBP7112P_18535	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XcvCFBP7112P_18585	COG2011	ABC-type metal ion transport system permease component
XcvCFBP7112P_18590	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
XcvCFBP7112P_18595	COG0697	spore germination
XcvCFBP7112P_18600	COG1666	GTP binding
XcvCFBP7112P_18630	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XcvCFBP7112P_18635	COG1187	pseudouridine synthase activity
XcvCFBP7112P_18640	COG2813	Specifically methylates the guanine in position
XcvCFBP7112P_18660	COG2202	Pas domain
XcvCFBP7112P_18660	COG2205	protein histidine kinase activity
XcvCFBP7112P_18680	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
XcvCFBP7112P_18685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XcvCFBP7112P_18690	COG1522	sequence-specific DNA binding
XcvCFBP7112P_18740	COG0842	Transport permease protein
XcvCFBP7112P_18745	COG1131	(ABC) transporter
XcvCFBP7112P_18750	COG0025	NhaP-type Na H and K H
XcvCFBP7112P_18760	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
XcvCFBP7112P_18765	COG1573	uracil-dna glycosylase
XcvCFBP7112P_18775	COG3384	dioxygenase
XcvCFBP7112P_18785	COG0583	DNA-binding transcription factor activity
XcvCFBP7112P_18795	COG0667	Aldo Keto reductase
XcvCFBP7112P_18805	COG3590	peptidase
XcvCFBP7112P_18820	COG0531	amino acid
XcvCFBP7112P_18835	COG2972	Histidine kinase
XcvCFBP7112P_18860	COG3685	Protein conserved in bacteria
XcvCFBP7112P_18865	COG3546	catalase activity
XcvCFBP7112P_18900	COG2204	response regulator
XcvCFBP7112P_18915	COG1271	oxidase subunit
XcvCFBP7112P_18920	COG1294	oxidase, subunit
XcvCFBP7112P_18935	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7112P_18960	COG1132	(ABC) transporter
XcvCFBP7112P_18975	COG1063	alcohol dehydrogenase
XcvCFBP7112P_19050	COG0251	oxidation-reduction process
XcvCFBP7112P_19065	COG0840	transmembrane signaling receptor activity
XcvCFBP7112P_19080	COG0583	DNA-binding transcription factor activity
XcvCFBP7112P_19085	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XcvCFBP7112P_19115	COG0659	secondary active sulfate transmembrane transporter activity
XcvCFBP7112P_19150	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XcvCFBP7112P_19155	COG1490	D-aminoacyl-tRNA deacylase activity
XcvCFBP7112P_19160	COG1560	Kdo2-lipid A biosynthetic process
XcvCFBP7112P_19215	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XcvCFBP7112P_19215	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
XcvCFBP7112P_19220	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
XcvCFBP7112P_19225	COG0242	peptide deformylase activity
XcvCFBP7112P_19230	COG1652	LysM domain
XcvCFBP7112P_19235	COG0758	DNA mediated transformation
XcvCFBP7112P_19255	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XcvCFBP7112P_19255	COG1754	DNA topoisomerase type I activity
XcvCFBP7112P_19260	COG0009	L-threonylcarbamoyladenylate synthase
XcvCFBP7112P_19275	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7112P_19285	COG0616	signal peptide processing
XcvCFBP7112P_19290	COG0534	Mate efflux family protein
XcvCFBP7112P_19310	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
XcvCFBP7112P_19315	COG0625	glutathione transferase activity
XcvCFBP7112P_19330	COG1252	NADH dehydrogenase
XcvCFBP7112P_19335	COG2860	membrane
XcvCFBP7112P_19340	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XcvCFBP7112P_19345	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
XcvCFBP7112P_19350	COG3437	response regulator, receiver
XcvCFBP7112P_19355	COG2177	Part of the ABC transporter FtsEX involved in
XcvCFBP7112P_19360	COG2884	Cell division ATP-binding protein ftsE
XcvCFBP7112P_19365	COG0513	Belongs to the DEAD box helicase family
XcvCFBP7112P_19370	COG3118	belongs to the thioredoxin family
XcvCFBP7112P_19375	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
XcvCFBP7112P_19380	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
XcvCFBP7112P_19385	COG0583	DNA-binding transcription factor activity
XcvCFBP7112P_19405	COG1652	LysM domain
XcvCFBP7112P_19410	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XcvCFBP7112P_19410	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XcvCFBP7112P_19415	COG1473	amidohydrolase
XcvCFBP7112P_19420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcvCFBP7112P_19425	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XcvCFBP7112P_19445	COG5383	Protein conserved in bacteria
XcvCFBP7112P_19490	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
XcvCFBP7112P_19495	COG3023	N-Acetylmuramoyl-L-alanine amidase
XcvCFBP7112P_19505	COG4948	Mandelate Racemase Muconate Lactonizing
XcvCFBP7112P_19515	COG0531	amino acid
XcvCFBP7112P_19530	COG4682	membrane
XcvCFBP7112P_19535	COG2133	pyrroloquinoline quinone binding
XcvCFBP7112P_19545	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
XcvCFBP7112P_19550	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
XcvCFBP7112P_19555	COG0828	Belongs to the bacterial ribosomal protein bS21 family
XcvCFBP7112P_19560	COG1610	YqeY-like protein
XcvCFBP7112P_19570	COG1295	ribonuclease BN
XcvCFBP7112P_19575	COG0358	DNA primase activity
XcvCFBP7112P_19590	COG0109	protoheme IX farnesyltransferase activity
XcvCFBP7112P_19620	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
XcvCFBP7112P_19635	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XcvCFBP7112P_19680	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
XcvCFBP7112P_19685	COG0739	heme binding
XcvCFBP7112P_19690	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
XcvCFBP7112P_19700	COG2211	Major facilitator Superfamily
XcvCFBP7112P_19705	COG0708	Exodeoxyribonuclease III
XcvCFBP7112P_19710	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
XcvCFBP7112P_19720	COG1192	Involved in chromosome partitioning
XcvCFBP7112P_19725	COG1475	DNA binding
XcvCFBP7112P_19745	COG0463	Glycosyl transferase, family 2
XcvCFBP7112P_19765	COG0756	dUTP diphosphatase activity
XcvCFBP7112P_19770	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
XcvCFBP7112P_19775	COG2003	Belongs to the UPF0758 family
XcvCFBP7112P_19780	COG0018	arginyl-trna synthetase
XcvCFBP7112P_19795	COG4221	oxidoreductase activity
XcvCFBP7112P_19800	COG2755	lipolytic protein G-D-S-L family
XcvCFBP7112P_19800	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
XcvCFBP7112P_19810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XcvCFBP7112P_19815	COG1166	arginine decarboxylase activity
XcvCFBP7112P_19820	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
XcvCFBP7112P_19840	COG3525	Glycosyl hydrolase, family 20, catalytic domain
XcvCFBP7112P_19840	COG3291	Pkd domain containing protein
XcvCFBP7112P_19860	COG0606	chelatase, subunit chli
XcvCFBP7112P_19895	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
XcvCFBP7112P_19915	COG0210	DNA helicase
XcvCFBP7112P_19925	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
XcvCFBP7112P_19970	COG0606	chelatase, subunit chli
XcvCFBP7112P_19985	COG4943	cyclic-guanylate-specific phosphodiesterase activity
XcvCFBP7112P_20025	COG1690	Belongs to the RtcB family
XcvCFBP7112P_20060	COG1090	epimerase
XcvCFBP7112P_20065	COG0745	RESPONSE REGULATOR receiver
XcvCFBP7112P_20070	COG0642	Histidine kinase
XcvCFBP7112P_20095	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XcvCFBP7112P_20120	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XcvCFBP7112P_20125	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XcvCFBP7112P_20140	COG0753	catalase activity
XcvCFBP7112P_20155	COG2197	response regulator
XcvCFBP7112P_20160	COG4585	Histidine kinase
XcvCFBP7112P_20165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcvCFBP7112P_20170	COG1136	(ABC) transporter
XcvCFBP7112P_20195	COG0697	spore germination
XcvCFBP7112P_20215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XcvCFBP7112P_20220	COG0180	Tryptophanyl-tRNA synthetase
XcvCFBP7112P_20225	COG3237	CsbD-like
XcvCFBP7112P_20265	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
XcvCFBP7112P_20280	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
XcvCFBP7112P_20285	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
XcvCFBP7112P_20285	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
XcvCFBP7112P_20315	COG2205	protein histidine kinase activity
XcvCFBP7112P_20320	COG0745	RESPONSE REGULATOR receiver
XcvCFBP7112P_20330	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XcvCFBP7112P_20360	COG1199	ATP-dependent helicase activity
XcvCFBP7112P_20375	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
XcvCFBP7112P_20445	COG0625	glutathione transferase activity
XcvCFBP7112P_20480	COG4555	ABC transporter
XcvCFBP7112P_20490	COG1476	TRANSCRIPTIONal
XcvCFBP7112P_20510	COG1230	cation diffusion facilitator family transporter
XcvCFBP7112P_20520	COG4774	siderophore transport
XcvCFBP7112P_20535	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XcvCFBP7112P_20540	COG1131	(ABC) transporter
XcvCFBP7112P_20545	COG0842	Transport permease protein
XcvCFBP7112P_20550	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XcvCFBP7112P_20565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XcvCFBP7112P_20580	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XcvCFBP7112P_20590	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XcvCFBP7112P_20605	COG0045	succinate-CoA ligase (ADP-forming) activity
XcvCFBP7112P_20605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XcvCFBP7112P_20605	COG1042	CoA-binding domain protein
XcvCFBP7112P_20610	COG2239	Acts as a magnesium transporter
XcvCFBP7112P_20630	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XcvCFBP7112P_20635	COG3387	PFAM Glycoside hydrolase 15-related
XcvCFBP7112P_20650	COG3100	YcgL domain-containing protein
XcvCFBP7112P_20655	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XcvCFBP7112P_20665	COG0463	Glycosyl transferase, family 2
XcvCFBP7112P_20675	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7112P_20730	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XcvCFBP7112P_20745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XcvCFBP7112P_20775	COG4946	Tricorn protease homolog
XcvCFBP7112P_20775	COG1506	peptidase
XcvCFBP7112P_20775	COG0823	Involved in the tonB-independent uptake of proteins
XcvCFBP7112P_20795	COG0408	coproporphyrinogen oxidase activity
XcvCFBP7112P_20835	COG0515	serine threonine protein kinase
XcvCFBP7112P_20840	COG0631	protein serine/threonine phosphatase activity
XcvCFBP7112P_20865	COG0667	Aldo Keto reductase
XcvCFBP7112P_20870	COG0583	DNA-binding transcription factor activity
XcvCFBP7112P_20885	COG3501	Rhs element vgr protein
XcvCFBP7112P_20910	COG1595	DNA-templated transcription, initiation
XcvCFBP7112P_21025	COG0210	DNA helicase
XcvCFBP7112P_21035	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XcvCFBP7112P_21045	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XcvCFBP7112P_21060	COG2159	amidohydrolase
XcvCFBP7112P_21065	COG0267	Belongs to the bacterial ribosomal protein bL33 family
XcvCFBP7112P_21070	COG0227	Belongs to the bacterial ribosomal protein bL28 family
XcvCFBP7112P_21090	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XcvCFBP7112P_21110	COG0357	Ribosomal RNA small subunit methyltransferase G
XcvCFBP7112P_21115	COG3540	Alkaline phosphatase
XcvCFBP7112P_21125	COG2091	lysine biosynthetic process via aminoadipic acid
XcvCFBP7112P_21140	COG0708	Exodeoxyribonuclease III
XcvCFBP7112P_21145	COG1940	carbohydrate kinase activity
XcvCFBP7112P_21145	COG1846	Transcriptional regulator
XcvCFBP7112P_21155	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XcvCFBP7112P_21170	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XcvCFBP7112P_21175	COG3162	membrane
XcvCFBP7112P_21185	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XcvCFBP7112P_21215	COG3507	Belongs to the glycosyl hydrolase 43 family
XcvCFBP7112P_21235	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7112P_21240	COG0179	Fumarylacetoacetate (FAA) hydrolase
XcvCFBP7112P_21245	COG4948	Mandelate Racemase Muconate Lactonizing
XcvCFBP7112P_21250	COG3254	rhamnose metabolic process
XcvCFBP7112P_21255	COG0738	Major facilitator superfamily
XcvCFBP7112P_21260	COG1414	Transcriptional regulator
XcvCFBP7112P_21265	COG1971	Probably functions as a manganese efflux pump
XcvCFBP7112P_21270	COG2205	protein histidine kinase activity
XcvCFBP7112P_21285	COG3459	Glycosyltransferase 36 associated
XcvCFBP7112P_21290	COG2211	Major facilitator Superfamily
XcvCFBP7112P_21295	COG3265	gluconokinase activity
XcvCFBP7112P_21305	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XcvCFBP7112P_21325	COG2911	Protein conserved in bacteria
XcvCFBP7112P_21330	COG0729	surface antigen
XcvCFBP7112P_21365	COG0752	glycyl-tRNA synthetase alpha subunit
XcvCFBP7112P_21370	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XcvCFBP7112P_21385	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XcvCFBP7112P_21385	COG0519	Catalyzes the synthesis of GMP from XMP
XcvCFBP7112P_21395	COG0805	protein transport
XcvCFBP7112P_21400	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XcvCFBP7112P_21405	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XcvCFBP7112P_21415	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
XcvCFBP7112P_21435	COG2974	May be involved in recombination
XcvCFBP7112P_21440	COG0037	tRNA processing
XcvCFBP7112P_21445	COG2115	Belongs to the xylose isomerase family
XcvCFBP7112P_21455	COG3661	Belongs to the glycosyl hydrolase 67 family
XcvCFBP7112P_21465	COG4948	Mandelate Racemase Muconate Lactonizing
XcvCFBP7112P_21475	COG1472	Belongs to the glycosyl hydrolase 3 family
XcvCFBP7112P_21480	COG0246	Mannitol dehydrogenase
XcvCFBP7112P_21530	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XcvCFBP7112P_21540	COG1070	Carbohydrate kinase
XcvCFBP7112P_21560	COG3386	PFAM SMP-30 Gluconolaconase
XcvCFBP7112P_21570	COG3250	beta-galactosidase activity
XcvCFBP7112P_21575	COG1904	glucuronate isomerase
XcvCFBP7112P_21590	COG3693	PFAM glycoside hydrolase, family 10
XcvCFBP7112P_21605	COG2211	Major facilitator Superfamily
XcvCFBP7112P_21650	COG0604	alcohol dehydrogenase
XcvCFBP7112P_21650	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7112P_21650	COG3321	synthase
XcvCFBP7112P_21655	COG2937	Belongs to the GPAT DAPAT family
XcvCFBP7112P_21690	COG0284	orotidine-5'-phosphate decarboxylase activity
XcvCFBP7112P_21695	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
XcvCFBP7112P_21700	COG3132	Protein of unknown function, DUF480
XcvCFBP7112P_21715	COG0210	DNA helicase
XcvCFBP7112P_21720	COG1435	thymidine kinase activity
XcvCFBP7112P_21730	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
XcvCFBP7112P_21740	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
XcvCFBP7112P_21770	COG3135	benzoate transporter
XcvCFBP7112P_21790	COG0676	glucose-6-phosphate 1-epimerase activity
XcvCFBP7112P_21800	COG3012	SEC-C Motif Domain Protein
XcvCFBP7112P_21805	COG0730	response to heat
XcvCFBP7112P_21825	COG0302	gtp cyclohydrolase
XcvCFBP7112P_21840	COG1566	PFAM secretion protein HlyD family protein
XcvCFBP7112P_21850	COG1289	transmembrane transporter activity
XcvCFBP7112P_21855	COG0477	Major facilitator Superfamily
XcvCFBP7112P_21865	COG0583	DNA-binding transcription factor activity
XcvCFBP7112P_21870	COG4221	oxidoreductase activity
XcvCFBP7112P_21880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XcvCFBP7112P_21935	COG0564	pseudouridine synthase activity
XcvCFBP7112P_21980	COG1028	Short-chain dehydrogenase reductase Sdr
XcvCFBP7112P_22025	COG1074	ATP-dependent DNA helicase activity
XcvCFBP7112P_22030	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
XcvCFBP7112P_22070	COG1127	ABC transporter
XcvCFBP7112P_22075	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XcvCFBP7112P_22080	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XcvCFBP7112P_22095	COG2853	Lipoprotein
XcvCFBP7112P_22105	COG0386	Belongs to the glutathione peroxidase family
XcvCFBP7112P_22115	COG1322	Protein conserved in bacteria
XcvCFBP7112P_22130	COG0625	glutathione transferase activity
XcvCFBP7112P_22140	COG0531	amino acid
XcvCFBP7112P_22145	COG3537	Alpha-1,2-mannosidase
XcvCFBP7112P_22160	COG3706	GGDEF domain
XcvCFBP7112P_22165	COG3835	regulator
XcvCFBP7112P_22170	COG1929	Belongs to the glycerate kinase type-1 family
XcvCFBP7112P_22175	COG2271	Major facilitator Superfamily
XcvCFBP7112P_22190	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XcvCFBP7112P_22195	COG0861	Integral membrane protein TerC family
XcvCFBP7112P_22205	COG0584	glycerophosphoryl diester phosphodiesterase
XcvCFBP7112P_22220	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
XcvCFBP7112P_22230	COG0706	membrane insertase activity
XcvCFBP7112P_22235	COG0594	ribonuclease P activity
XcvCFBP7112P_22240	COG0230	Belongs to the bacterial ribosomal protein bL34 family
XcvCFBP7112P_22290	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XcvCFBP7112P_22345	COG2951	lytic endotransglycosylase activity
XcvCFBP7112P_22460	COG0489	protein tyrosine kinase activity
XcvCFBP7112P_22635	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XcvCFBP7112P_22700	COG3318	Belongs to the UPF0149 family
XcvCFBP7112P_22700	COG3012	SEC-C Motif Domain Protein
XcvCFBP7112P_22720	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs