locus-tag	class	description
BI317_00005	COG1074	ATP-dependent DNA helicase activity
BI317_00010	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BI317_00015	COG1127	ABC transporter
BI317_00020	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BI317_00025	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BI317_00040	COG2853	Lipoprotein
BI317_00065	COG0386	Belongs to the glutathione peroxidase family
BI317_00075	COG1322	Protein conserved in bacteria
BI317_00080	COG0625	glutathione transferase activity
BI317_00085	COG0531	amino acid
BI317_00090	COG3537	Alpha-1,2-mannosidase
BI317_00105	COG2199	diguanylate cyclase activity
BI317_00105	COG2203	Gaf domain
BI317_00110	COG3835	regulator
BI317_00115	COG1929	Belongs to the glycerate kinase type-1 family
BI317_00120	COG2271	Major facilitator Superfamily
BI317_00160	COG1126	abc transporter atp-binding protein
BI317_00170	COG1473	amidohydrolase
BI317_00175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BI317_00180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BI317_00190	COG4206	TonB-dependent receptor
BI317_00210	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BI317_00220	COG0861	Integral membrane protein TerC family
BI317_00240	COG0584	glycerophosphoryl diester phosphodiesterase
BI317_00265	COG0706	membrane insertase activity
BI317_00275	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BI317_00300	COG0187	DNA topoisomerase II activity
BI317_00310	COG0501	Belongs to the peptidase M48B family
BI317_00345	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BI317_00355	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BI317_00385	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BI317_00390	COG0793	Belongs to the peptidase S41A family
BI317_00395	COG4942	peptidase
BI317_00405	COG2234	aminopeptidase activity
BI317_00415	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BI317_00425	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BI317_00430	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BI317_00435	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BI317_00440	COG1064	alcohol dehydrogenase
BI317_00450	COG0493	'glutamate synthase
BI317_00455	COG0070	glutamate synthase
BI317_00455	COG0067	glutamate synthase
BI317_00455	COG0069	glutamate synthase activity
BI317_00485	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BI317_00500	COG3459	Glycosyltransferase 36 associated
BI317_00525	COG1028	Short-chain dehydrogenase reductase Sdr
BI317_00610	COG1111	helicase
BI317_00610	COG1205	dead DEAH box helicase
BI317_00620	COG1272	protein, Hemolysin III
BI317_00645	COG1028	Short-chain dehydrogenase reductase Sdr
BI317_00665	COG0583	DNA-binding transcription factor activity
BI317_00670	COG1028	Short-chain dehydrogenase reductase Sdr
BI317_00685	COG2249	NAD(P)H dehydrogenase (quinone) activity
BI317_00700	COG1733	regulation of RNA biosynthetic process
BI317_00715	COG3039	Transposase
BI317_00725	COG2963	transposase activity
BI317_00745	COG3237	CsbD-like
BI317_00780	COG2816	NAD+ diphosphatase activity
BI317_00795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BI317_00905	COG4772	TonB-dependent receptor
BI317_00915	COG0662	Cupin 2, conserved barrel domain protein
BI317_00925	COG1012	belongs to the aldehyde dehydrogenase family
BI317_00980	COG1755	Isoprenylcysteine carboxyl methyltransferase
BI317_00985	COG4585	Histidine kinase
BI317_00990	COG2197	response regulator
BI317_01005	COG3710	Transcriptional regulator
BI317_01010	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BI317_01020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BI317_01025	COG4771	TonB-dependent receptor
BI317_01155	COG3550	peptidyl-serine autophosphorylation
BI317_01205	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BI317_01215	COG4221	oxidoreductase activity
BI317_01220	COG0583	DNA-binding transcription factor activity
BI317_01225	COG0477	Major facilitator Superfamily
BI317_01230	COG1289	transmembrane transporter activity
BI317_01240	COG1566	PFAM secretion protein HlyD family protein
BI317_01255	COG0302	gtp cyclohydrolase
BI317_01285	COG0730	response to heat
BI317_01290	COG3012	SEC-C Motif Domain Protein
BI317_01300	COG0676	glucose-6-phosphate 1-epimerase activity
BI317_01350	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BI317_01360	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
BI317_01370	COG1435	thymidine kinase activity
BI317_01375	COG0210	DNA helicase
BI317_01395	COG3132	Protein of unknown function, DUF480
BI317_01400	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BI317_01405	COG0284	orotidine-5'-phosphate decarboxylase activity
BI317_01430	COG2937	Belongs to the GPAT DAPAT family
BI317_01475	COG2211	Major facilitator Superfamily
BI317_01490	COG3693	PFAM glycoside hydrolase, family 10
BI317_01495	COG1904	glucuronate isomerase
BI317_01500	COG3250	beta-galactosidase activity
BI317_01510	COG3386	PFAM SMP-30 Gluconolaconase
BI317_01520	COG1620	l-lactate permease
BI317_01525	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BI317_01550	COG0246	Mannitol dehydrogenase
BI317_01555	COG1472	Belongs to the glycosyl hydrolase 3 family
BI317_01565	COG4948	Mandelate Racemase Muconate Lactonizing
BI317_01585	COG2115	Belongs to the xylose isomerase family
BI317_01590	COG0037	tRNA processing
BI317_01595	COG2974	May be involved in recombination
BI317_01615	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BI317_01625	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BI317_01630	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BI317_01635	COG0805	protein transport
BI317_01645	COG0519	Catalyzes the synthesis of GMP from XMP
BI317_01645	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BI317_01660	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BI317_01675	COG0729	surface antigen
BI317_01680	COG2911	Protein conserved in bacteria
BI317_01715	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BI317_01720	COG3265	gluconokinase activity
BI317_01725	COG2211	Major facilitator Superfamily
BI317_01730	COG3459	Glycosyltransferase 36 associated
BI317_01740	COG2205	protein histidine kinase activity
BI317_01745	COG1971	Probably functions as a manganese efflux pump
BI317_01760	COG1414	Transcriptional regulator
BI317_01765	COG0738	Major facilitator superfamily
BI317_01770	COG3254	rhamnose metabolic process
BI317_01775	COG4948	Mandelate Racemase Muconate Lactonizing
BI317_01785	COG1028	Short-chain dehydrogenase reductase Sdr
BI317_01855	COG3162	membrane
BI317_01860	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BI317_01880	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BI317_01890	COG1940	carbohydrate kinase activity
BI317_01905	COG0708	Exodeoxyribonuclease III
BI317_01920	COG2091	lysine biosynthetic process via aminoadipic acid
BI317_01930	COG3540	Alkaline phosphatase
BI317_01965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BI317_01975	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BI317_01980	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BI317_01985	COG2159	amidohydrolase
BI317_01995	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BI317_02005	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BI317_02020	COG0210	DNA helicase
BI317_02075	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BI317_02075	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BI317_02125	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BI317_02140	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BI317_02170	COG1028	Short-chain dehydrogenase reductase Sdr
BI317_02210	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BI317_02215	COG3100	YcgL domain-containing protein
BI317_02230	COG3387	PFAM Glycoside hydrolase 15-related
BI317_02235	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BI317_02250	COG2239	Acts as a magnesium transporter
BI317_02255	COG4771	TonB-dependent receptor
BI317_02255	COG1629	transport
BI317_02270	COG0045	succinate-CoA ligase (ADP-forming) activity
BI317_02270	COG1042	CoA-binding domain protein
BI317_02270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BI317_02290	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BI317_02300	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BI317_02315	COG1607	acyl-coa hydrolase
BI317_02335	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BI317_02345	COG0842	Transport permease protein
BI317_02350	COG1131	(ABC) transporter
BI317_02355	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BI317_02380	COG1476	TRANSCRIPTIONal
BI317_02390	COG4555	ABC transporter
BI317_02425	COG0625	glutathione transferase activity
BI317_02465	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BI317_02470	COG3293	Transposase
BI317_02510	COG1199	ATP-dependent helicase activity
BI317_02535	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BI317_02545	COG0745	RESPONSE REGULATOR receiver
BI317_02550	COG2205	protein histidine kinase activity
BI317_02565	COG3228	Belongs to the MtfA family
BI317_02575	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BI317_02575	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BI317_02580	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BI317_02595	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BI317_02635	COG3237	CsbD-like
BI317_02640	COG0180	Tryptophanyl-tRNA synthetase
BI317_02680	COG0697	spore germination
BI317_02705	COG1136	(ABC) transporter
BI317_02710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BI317_02715	COG4585	Histidine kinase
BI317_02720	COG2197	response regulator
BI317_02745	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BI317_02750	COG1011	Hydrolase
BI317_02775	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BI317_02795	COG0642	Histidine kinase
BI317_02805	COG1090	epimerase
BI317_02855	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BI317_02870	COG0606	chelatase, subunit chli
BI317_02875	COG2960	long-chain fatty acid transporting porin activity
BI317_02910	COG1166	arginine decarboxylase activity
BI317_02915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BI317_02925	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BI317_02925	COG2755	lipolytic protein G-D-S-L family
BI317_02930	COG4221	oxidoreductase activity
BI317_02940	COG0018	arginyl-trna synthetase
BI317_02950	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BI317_02955	COG0756	dUTP diphosphatase activity
BI317_02975	COG0463	Glycosyl transferase, family 2
BI317_02990	COG1475	DNA binding
BI317_02995	COG1192	Involved in chromosome partitioning
BI317_03010	COG0708	Exodeoxyribonuclease III
BI317_03015	COG2807	transmembrane transport
BI317_03030	COG0739	heme binding
BI317_03075	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BI317_03085	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
BI317_03115	COG0109	protoheme IX farnesyltransferase activity
BI317_03130	COG0358	DNA primase activity
BI317_03135	COG1295	ribonuclease BN
BI317_03140	COG1610	YqeY-like protein
BI317_03145	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BI317_03155	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BI317_03170	COG3293	Transposase
BI317_03175	COG2133	pyrroloquinoline quinone binding
BI317_03180	COG4682	membrane
BI317_03195	COG0531	amino acid
BI317_03210	COG5383	Protein conserved in bacteria
BI317_03250	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
BI317_03255	COG3023	N-Acetylmuramoyl-L-alanine amidase
BI317_03265	COG4948	Mandelate Racemase Muconate Lactonizing
BI317_03280	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BI317_03285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BI317_03290	COG1473	amidohydrolase
BI317_03295	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BI317_03295	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BI317_03325	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
BI317_03345	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BI317_03350	COG3118	belongs to the thioredoxin family
BI317_03360	COG2884	Cell division ATP-binding protein ftsE
BI317_03365	COG2177	Part of the ABC transporter FtsEX involved in
BI317_03370	COG2201	protein-glutamate methylesterase activity
BI317_03375	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BI317_03380	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BI317_03385	COG2860	membrane
BI317_03405	COG0625	glutathione transferase activity
BI317_03410	COG3293	Transposase
BI317_03420	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BI317_03435	COG0534	Mate efflux family protein
BI317_03440	COG0616	signal peptide processing
BI317_03450	COG1028	Short-chain dehydrogenase reductase Sdr
BI317_03465	COG0009	L-threonylcarbamoyladenylate synthase
BI317_03470	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BI317_03470	COG1754	DNA topoisomerase type I activity
BI317_03490	COG0758	DNA mediated transformation
BI317_03495	COG1652	LysM domain
BI317_03500	COG0242	peptide deformylase activity
BI317_03505	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BI317_03510	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BI317_03510	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BI317_03550	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BI317_03560	COG1560	Kdo2-lipid A biosynthetic process
BI317_03565	COG1490	D-aminoacyl-tRNA deacylase activity
BI317_03570	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BI317_03590	COG3039	Transposase
BI317_03645	COG1522	sequence-specific DNA binding
BI317_03650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BI317_03655	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BI317_03675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BI317_03675	COG2205	protein histidine kinase activity
BI317_03675	COG2198	Histidine kinase
BI317_03675	COG0784	Response regulator, receiver
BI317_03700	COG2813	Specifically methylates the guanine in position
BI317_03705	COG1187	pseudouridine synthase activity
BI317_03725	COG1666	GTP binding
BI317_03730	COG0697	spore germination
BI317_03735	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BI317_03740	COG2011	ABC-type metal ion transport system permease component
BI317_03770	COG0508	dehydrogenase complex catalyzes the overall conversion of
BI317_03780	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BI317_03795	COG0356	it plays a direct role in the translocation of protons across the membrane
BI317_03805	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BI317_03810	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BI317_03830	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BI317_03845	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BI317_03855	COG3293	Transposase
BI317_03865	COG4191	Histidine kinase
BI317_03870	COG2204	response regulator
BI317_03875	COG0577	efflux transmembrane transporter activity
BI317_03885	COG1136	(ABC) transporter
BI317_03895	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BI317_03900	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BI317_03945	COG0339	signal peptide processing
BI317_03960	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BI317_03965	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BI317_03970	COG0546	phosphoglycolate phosphatase activity
BI317_03980	COG2819	hydrolase of the alpha beta superfamily
BI317_03990	COG1956	GAF domain-containing protein
BI317_03995	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BI317_04005	COG0720	synthase
BI317_04010	COG4771	TonB-dependent receptor
BI317_04020	COG0513	Belongs to the DEAD box helicase family
BI317_04035	COG0625	glutathione transferase activity
BI317_04105	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
BI317_04130	COG0463	Glycosyl transferase, family 2
BI317_04150	COG2086	electron transfer activity
BI317_04175	COG0662	Cupin 2, conserved barrel domain protein
BI317_04175	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BI317_04180	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BI317_04225	COG3218	ABC-type transport auxiliary lipoprotein component
BI317_04225	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BI317_04230	COG1127	ABC transporter
BI317_04235	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BI317_04260	COG1183	phosphatidylcholine synthase activity
BI317_04290	COG0525	valine-tRNA ligase activity
BI317_04310	COG0795	lipopolysaccharide-transporting ATPase activity
BI317_04325	COG4974	Belongs to the 'phage' integrase family
BI317_04330	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BI317_04335	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BI317_04335	COG0047	phosphoribosylformylglycinamidine synthase activity
BI317_04345	COG1404	Belongs to the peptidase S8 family
BI317_04350	COG5295	Hep Hag repeat protein
BI317_04355	COG1404	Belongs to the peptidase S8 family
BI317_04360	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BI317_04365	COG1459	type II secretion system
BI317_04370	COG2165	general secretion pathway protein
BI317_04375	COG4970	Tfp pilus assembly protein FimT
BI317_04380	COG2165	general secretion pathway protein
BI317_04385	COG4795	General secretion pathway protein
BI317_04390	COG3156	type II secretion system protein K
BI317_04395	COG3166	PFAM Fimbrial assembly family protein
BI317_04410	COG1450	Type ii and iii secretion system protein
BI317_04455	COG2188	Transcriptional regulator
BI317_04500	COG3293	Transposase
BI317_04510	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BI317_04525	COG0242	peptide deformylase activity
BI317_04530	COG0488	(ABC) transporter
BI317_04540	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BI317_04555	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BI317_04555	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BI317_04595	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BI317_04620	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BI317_04625	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BI317_04635	COG2205	protein histidine kinase activity
BI317_04640	COG0745	RESPONSE REGULATOR receiver
BI317_04645	COG0277	FAD linked oxidase domain protein
BI317_04650	COG1988	membrane-bound metal-dependent
BI317_04700	COG3116	cell division
BI317_04710	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BI317_04715	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BI317_04735	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BI317_04740	COG1181	Belongs to the D-alanine--D-alanine ligase family
BI317_04745	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BI317_04770	COG0739	heme binding
BI317_04775	COG0653	protein targeting
BI317_04785	COG0494	nUDIX hydrolase
BI317_04805	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BI317_04815	COG0604	alcohol dehydrogenase
BI317_04815	COG1028	Short-chain dehydrogenase reductase Sdr
BI317_04815	COG3321	synthase
BI317_04880	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BI317_04900	COG2885	chlorophyll binding
BI317_04915	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BI317_04925	COG4106	trans-aconitate 2-methyltransferase activity
BI317_04930	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BI317_04945	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BI317_04950	COG0667	Aldo Keto reductase
BI317_04960	COG4771	TonB-dependent receptor
BI317_05005	COG2963	transposase activity
BI317_05020	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BI317_05025	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BI317_05045	COG4181	ATPase activity
BI317_05060	COG0642	Histidine kinase
BI317_05070	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BI317_05090	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BI317_05110	COG1116	anion transmembrane transporter activity
BI317_05115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BI317_05125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BI317_05130	COG0431	NADPH-dependent FMN reductase
BI317_05135	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BI317_05140	COG2967	ApaG domain
BI317_05145	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BI317_05150	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BI317_05160	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BI317_05165	COG0123	including yeast histone deacetylase and acetoin utilization protein
BI317_05170	COG2096	Adenosyltransferase
BI317_05180	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BI317_05185	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BI317_05215	COG3384	dioxygenase
BI317_05220	COG0583	DNA-binding transcription factor activity
BI317_05225	COG0318	PFAM AMP-dependent synthetase and ligase
BI317_05235	COG1024	Enoyl-CoA hydratase
BI317_05260	COG3386	PFAM SMP-30 Gluconolaconase
BI317_05290	COG0697	spore germination
BI317_05295	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BI317_05310	COG3706	GGDEF domain
BI317_05310	COG0745	RESPONSE REGULATOR receiver
BI317_05315	COG0784	Response regulator, receiver
BI317_05315	COG5002	protein histidine kinase activity
BI317_05315	COG2205	protein histidine kinase activity
BI317_05320	COG2197	response regulator
BI317_05330	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BI317_05340	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BI317_05345	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BI317_05350	COG0583	DNA-binding transcription factor activity
BI317_05355	COG3634	alkyl hydroperoxide reductase activity
BI317_05365	COG2890	protein-(glutamine-N5) methyltransferase activity
BI317_05385	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BI317_05385	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BI317_05435	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BI317_05440	COG1404	Belongs to the peptidase S8 family
BI317_05445	COG1404	Belongs to the peptidase S8 family
BI317_05450	COG1404	Belongs to the peptidase S8 family
BI317_05475	COG1295	ribonuclease BN
BI317_05480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BI317_05500	COG0521	Mo-molybdopterin cofactor biosynthetic process
BI317_05520	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BI317_05530	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BI317_05545	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BI317_05550	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BI317_05555	COG0193	aminoacyl-tRNA hydrolase activity
BI317_05560	COG0012	GTP binding
BI317_05580	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BI317_05590	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BI317_05595	COG0250	Participates in transcription elongation, termination and antitermination
BI317_05600	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BI317_05605	COG0081	regulation of translation
BI317_05610	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BI317_05615	COG0222	ribosome binding
BI317_05630	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BI317_05645	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BI317_05650	COG0051	transcription antitermination factor activity, RNA binding
BI317_05670	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BI317_05695	COG0255	Belongs to the universal ribosomal protein uL29 family
BI317_05700	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BI317_05705	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BI317_05710	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BI317_05720	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BI317_05740	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BI317_05755	COG0201	protein transport
BI317_05760	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BI317_05765	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BI317_05770	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BI317_05775	COG0202	RNA polymerase activity
BI317_05780	COG0203	ribosomal protein L17
BI317_05795	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BI317_05805	COG0154	amidase activity
BI317_05820	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BI317_05830	COG0625	glutathione transferase activity
BI317_05845	COG1902	pentaerythritol trinitrate reductase activity
BI317_05845	COG0446	pyridine nucleotide-disulphide oxidoreductase
BI317_05850	COG0604	alcohol dehydrogenase
BI317_05855	COG2885	chlorophyll binding
BI317_05875	COG0156	8-amino-7-oxononanoate synthase activity
BI317_05880	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BI317_05885	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BI317_05890	COG4208	sulfate ABC transporter
BI317_05895	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BI317_05905	COG1063	alcohol dehydrogenase
BI317_05925	COG0406	alpha-ribazole phosphatase activity
BI317_05935	COG0285	dihydrofolate synthase activity
BI317_05955	COG2833	Protein of unknown function (DUF455)
BI317_05960	COG3291	Pkd domain containing protein
BI317_05970	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BI317_05975	COG0671	phosphoesterase, PA-phosphatase related
BI317_05990	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BI317_06000	COG0745	RESPONSE REGULATOR receiver
BI317_06005	COG4783	chaperone-mediated protein folding
BI317_06020	COG0473	3-isopropylmalate dehydrogenase activity
BI317_06065	COG3293	Transposase
BI317_06300	COG4695	Portal protein
BI317_06350	COG0544	peptidyl-prolyl cis-trans isomerase activity
BI317_06355	COG0740	serine-type endopeptidase activity
BI317_06360	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BI317_06390	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BI317_06400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BI317_06415	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BI317_06420	COG0631	protein serine/threonine phosphatase activity
BI317_06435	COG0859	PFAM glycosyl transferase family 9
BI317_06445	COG1234	tRNA 3'-trailer cleavage
BI317_06450	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BI317_06460	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BI317_06465	COG0314	molybdopterin synthase activity
BI317_06485	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BI317_06495	COG0537	adenosine 5'-monophosphoramidase activity
BI317_06515	COG0714	Associated with various cellular activities
BI317_06535	COG0424	maF-like protein
BI317_06540	COG1399	metal-binding, possibly nucleic acid-binding protein
BI317_06545	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BI317_06550	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BI317_06560	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BI317_06570	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BI317_06580	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BI317_06585	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BI317_06605	COG4115	mRNA cleavage
BI317_06610	COG2161	toxin-antitoxin pair type II binding
BI317_06620	COG3829	transcription factor binding
BI317_06660	COG2373	Large extracellular alpha-helical protein
BI317_06680	COG4953	penicillin-binding protein 1C
BI317_06690	COG0678	peroxiredoxin activity
BI317_06710	COG0330	HflC and HflK could
BI317_06715	COG0330	HflC and HflK could
BI317_06760	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BI317_06775	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BI317_06785	COG2801	Transposase and inactivated derivatives
BI317_06790	COG2963	transposase activity
BI317_06850	COG0328	RNA-DNA hybrid ribonuclease activity
BI317_06850	COG0406	alpha-ribazole phosphatase activity
BI317_06855	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BI317_06870	COG1028	Short-chain dehydrogenase reductase Sdr
BI317_06880	COG3537	Alpha-1,2-mannosidase
BI317_06935	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BI317_06940	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BI317_06945	COG2080	2 iron, 2 sulfur cluster binding
BI317_07000	COG0587	DNA-directed DNA polymerase activity
BI317_07015	COG1297	OPT oligopeptide transporter protein
BI317_07025	COG0823	Involved in the tonB-independent uptake of proteins
BI317_07025	COG1506	peptidase
BI317_07035	COG1917	Cupin 2, conserved barrel domain protein
BI317_07035	COG2207	Transcriptional regulator
BI317_07045	COG0753	catalase activity
BI317_07055	COG0656	L-ascorbic acid biosynthetic process
BI317_07065	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BI317_07065	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BI317_07070	COG2814	Major facilitator Superfamily
BI317_07095	COG2194	sulfuric ester hydrolase activity
BI317_07110	COG0745	RESPONSE REGULATOR receiver
BI317_07115	COG5002	protein histidine kinase activity
BI317_07125	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BI317_07130	COG2894	cell division
BI317_07145	COG4585	Histidine kinase
BI317_07150	COG2197	response regulator
BI317_07165	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BI317_07215	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BI317_07230	COG1595	DNA-templated transcription, initiation
BI317_07240	COG1946	Acyl-CoA thioesterase
BI317_07245	COG1024	Enoyl-CoA hydratase
BI317_07255	COG0824	Thioesterase
BI317_07260	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BI317_07290	COG0196	riboflavin kinase activity
BI317_07300	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BI317_07320	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BI317_07325	COG1845	cytochrome c oxidase, subunit III
BI317_07330	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BI317_07345	COG3152	Membrane
BI317_07355	COG2207	Transcriptional regulator
BI317_07360	COG0326	Molecular chaperone. Has ATPase activity
BI317_07375	COG1902	pentaerythritol trinitrate reductase activity
BI317_07380	COG1366	Belongs to the anti-sigma-factor antagonist family
BI317_07385	COG1366	Belongs to the anti-sigma-factor antagonist family
BI317_07390	COG2172	sigma factor antagonist activity
BI317_07415	COG4771	TonB-dependent receptor
BI317_07425	COG5507	3-demethylubiquinone-9 3-methyltransferase
BI317_07430	COG2205	protein histidine kinase activity
BI317_07435	COG2201	protein-glutamate methylesterase activity
BI317_07440	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BI317_07445	COG3437	response regulator, receiver
BI317_07445	COG3850	Histidine kinase
BI317_07445	COG4999	Histidine kinase
BI317_07445	COG2205	protein histidine kinase activity
BI317_07450	COG4191	Histidine kinase
BI317_07450	COG0784	Response regulator, receiver
BI317_07475	COG3534	alpha-L-arabinofuranosidase
BI317_07495	COG3039	Transposase
BI317_07515	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BI317_07545	COG0336	Belongs to the RNA methyltransferase TrmD family
BI317_07555	COG0534	Mate efflux family protein
BI317_07570	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
BI317_07580	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BI317_07640	COG1301	dicarboxylic acid transport
BI317_07645	COG4948	Mandelate Racemase Muconate Lactonizing
BI317_07650	COG3250	beta-galactosidase activity
BI317_07655	COG3867	Arabinogalactan endo-beta-1,4-galactanase
BI317_07675	COG1960	acyl-CoA dehydrogenase activity
BI317_07680	COG1024	Enoyl-CoA hydratase
BI317_07720	COG0457	Tetratricopeptide repeat
BI317_07730	COG1250	3-hydroxyacyl-CoA dehydrogenase
BI317_07730	COG1024	Enoyl-CoA hydratase
BI317_07745	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BI317_07770	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BI317_07775	COG1381	Involved in DNA repair and RecF pathway recombination
BI317_07805	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BI317_07810	COG1233	COG1233 Phytoene dehydrogenase and related
BI317_07815	COG3046	protein related to deoxyribodipyrimidine photolyase
BI317_07820	COG1472	Belongs to the glycosyl hydrolase 3 family
BI317_07830	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BI317_07835	COG1278	Cold shock
BI317_07840	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BI317_07850	COG1201	RNA secondary structure unwinding
BI317_07855	COG1793	dna ligase
BI317_07865	COG1793	dna ligase
BI317_07865	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BI317_07880	COG3706	GGDEF domain
BI317_07880	COG0745	RESPONSE REGULATOR receiver
BI317_07895	COG0183	Belongs to the thiolase family
BI317_07915	COG1451	nucleotide metabolic process
BI317_07920	COG5487	UPF0391 membrane protein
BI317_07930	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BI317_07970	COG1047	Peptidyl-prolyl cis-trans
BI317_07980	COG2824	Alkylphosphonate utilization operon protein PhnA
BI317_07995	COG1902	pentaerythritol trinitrate reductase activity
BI317_08035	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BI317_08035	COG0392	lysyltransferase activity
BI317_08045	COG0251	oxidation-reduction process
BI317_08090	COG1595	DNA-templated transcription, initiation
BI317_08105	COG2878	Part of a membrane complex involved in electron transport
BI317_08115	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BI317_08115	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BI317_08130	COG1131	(ABC) transporter
BI317_08135	COG0346	lactoylglutathione lyase activity
BI317_08140	COG0833	amino acid
BI317_08145	COG2040	homocysteine
BI317_08165	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BI317_08205	COG1695	Transcriptional regulator
BI317_08225	COG3293	Transposase
BI317_08250	COG0825	malonyl-CoA metabolic process
BI317_08265	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BI317_08270	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BI317_08275	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BI317_08280	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BI317_08295	COG0750	zinc metalloprotease
BI317_08300	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BI317_08305	COG0575	Belongs to the CDS family
BI317_08310	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BI317_08320	COG0528	UMP kinase activity
BI317_08325	COG3706	GGDEF domain
BI317_08325	COG0745	RESPONSE REGULATOR receiver
BI317_08330	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BI317_08335	COG0052	Belongs to the universal ribosomal protein uS2 family
BI317_08375	COG0024	Methionine aminopeptidase
BI317_08380	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BI317_08395	COG1393	Belongs to the ArsC family
BI317_08400	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BI317_08405	COG0367	asparagine synthase
BI317_08415	COG4774	siderophore transport
BI317_08440	COG3293	Transposase
BI317_08470	COG1566	PFAM secretion protein HlyD family protein
BI317_08475	COG2814	Major facilitator Superfamily
BI317_08535	COG0339	signal peptide processing
BI317_08540	COG0386	Belongs to the glutathione peroxidase family
BI317_08570	COG0288	reversible hydration of carbon dioxide
BI317_08605	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BI317_08610	COG0084	hydrolase, TatD family'
BI317_08625	COG1960	acyl-CoA dehydrogenase activity
BI317_08640	COG0367	asparagine synthase
BI317_08650	COG0305	Participates in initiation and elongation during chromosome replication
BI317_08660	COG0415	Belongs to the DNA photolyase family
BI317_08675	COG3118	belongs to the thioredoxin family
BI317_08685	COG0495	leucyl-tRNA aminoacylation
BI317_08700	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BI317_08720	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BI317_08740	COG1530	ribonuclease E activity
BI317_08745	COG3164	Protein of unknown function
BI317_08755	COG0312	modulator of DNA gyrase
BI317_08765	COG0312	modulator of DNA gyrase
BI317_08775	COG4104	PAAR repeat-containing protein
BI317_08780	COG0142	geranyltranstransferase activity
BI317_08785	COG1722	exodeoxyribonuclease VII activity
BI317_08790	COG0037	tRNA processing
BI317_08795	COG1785	Belongs to the alkaline phosphatase family
BI317_08800	COG1301	dicarboxylic acid transport
BI317_08815	COG0791	NLP P60 protein
BI317_08820	COG0791	NLP P60 protein
BI317_08825	COG1047	Peptidyl-prolyl cis-trans
BI317_08830	COG2311	Membrane
BI317_08835	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BI317_08860	COG3590	peptidase
BI317_08880	COG3039	Transposase
BI317_08895	COG0489	protein tyrosine kinase activity
BI317_08905	COG0717	Belongs to the dCTP deaminase family
BI317_08930	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BI317_08955	COG3039	Transposase
BI317_08980	COG0494	nUDIX hydrolase
BI317_08990	COG0433	COG0433 Predicted ATPase
BI317_09000	COG0688	phosphatidylethanolamine metabolic process
BI317_09010	COG2890	protein-(glutamine-N5) methyltransferase activity
BI317_09025	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BI317_09030	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BI317_09050	COG0135	phosphoribosylanthranilate isomerase activity
BI317_09060	COG0133	tryptophan synthase activity
BI317_09080	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BI317_09115	COG4221	oxidoreductase activity
BI317_09135	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BI317_09145	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BI317_09155	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BI317_09160	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BI317_09170	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BI317_09180	COG0839	Belongs to the complex I subunit 6 family
BI317_09185	COG0713	ATP synthesis coupled electron transport
BI317_09200	COG1007	ATP synthesis coupled electron transport
BI317_09210	COG0779	Required for maturation of 30S ribosomal subunits
BI317_09215	COG0195	Participates in both transcription termination and antitermination
BI317_09225	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BI317_09230	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BI317_09235	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BI317_09275	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BI317_09280	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BI317_09285	COG1028	Short-chain dehydrogenase reductase Sdr
BI317_09290	COG2095	MarC family integral membrane protein
BI317_09300	COG1611	Belongs to the LOG family
BI317_09345	COG0556	nucleotide-excision repair
BI317_09360	COG3505	Type IV secretory pathway VirD4
BI317_09380	COG2948	multi-organism process
BI317_09400	COG3702	type iv secretory pathway
BI317_09460	COG2963	transposase activity
BI317_09470	COG2801	Transposase and inactivated derivatives
BI317_09475	COG2963	transposase activity
BI317_09485	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BI317_09490	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BI317_09495	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BI317_09505	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BI317_09510	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BI317_09510	COG0072	phenylalanine-tRNA ligase activity
BI317_09515	COG0776	regulation of translation
BI317_09560	COG0438	transferase activity, transferring glycosyl groups
BI317_09565	COG0438	transferase activity, transferring glycosyl groups
BI317_09600	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BI317_09605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BI317_09610	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BI317_09635	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BI317_09655	COG3040	lipid binding
BI317_09800	COG3039	Transposase
BI317_09820	COG0740	serine-type endopeptidase activity
BI317_09885	COG2801	Transposase and inactivated derivatives
BI317_09890	COG2963	transposase activity
BI317_09990	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BI317_10025	COG1194	a g-specific adenine glycosylase
BI317_10030	COG0552	protein localization to endoplasmic reticulum
BI317_10040	COG3938	Belongs to the proline racemase family
BI317_10045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BI317_10060	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BI317_10070	COG0006	proline dipeptidase activity
BI317_10085	COG0531	amino acid
BI317_10190	COG0742	ribosomal rna small subunit methyltransferase
BI317_10210	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BI317_10215	COG0405	Gamma-glutamyltransferase
BI317_10225	COG3291	Pkd domain containing protein
BI317_10265	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BI317_10275	COG1862	Preprotein translocase
BI317_10285	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BI317_10315	COG3039	Transposase
BI317_10325	COG2963	transposase activity
BI317_10330	COG3293	Transposase
BI317_10345	COG2963	transposase activity
BI317_10350	COG2801	Transposase and inactivated derivatives
BI317_10370	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BI317_10370	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BI317_10375	COG1105	Belongs to the carbohydrate kinase PfkB family
BI317_10380	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BI317_10380	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BI317_10385	COG1609	Transcriptional regulator
BI317_10390	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BI317_10395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BI317_10405	COG2902	Dehydrogenase
BI317_10445	COG1064	alcohol dehydrogenase
BI317_10455	COG1902	pentaerythritol trinitrate reductase activity
BI317_10465	COG3293	Transposase
BI317_10475	COG0300	oxidoreductase activity
BI317_10480	COG0604	alcohol dehydrogenase
BI317_10490	COG0477	Major facilitator Superfamily
BI317_10500	COG0784	Response regulator, receiver
BI317_10500	COG2205	protein histidine kinase activity
BI317_10500	COG5002	protein histidine kinase activity
BI317_10505	COG2733	membrane
BI317_10530	COG0243	molybdopterin cofactor binding
BI317_10560	COG3706	GGDEF domain
BI317_10560	COG0745	RESPONSE REGULATOR receiver
BI317_10570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BI317_10575	COG0174	glutamine synthetase
BI317_10580	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BI317_10615	COG3842	ATPase activity
BI317_10625	COG1176	ABC-type spermidine putrescine transport system, permease component I
BI317_10630	COG1177	transmembrane transport
BI317_10640	COG1012	belongs to the aldehyde dehydrogenase family
BI317_10660	COG4535	Mg2 and Co2 transporter CorC
BI317_10680	COG1702	phosphate starvation-inducible protein PhoH
BI317_10685	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BI317_10700	COG0741	lytic transglycosylase activity
BI317_10705	COG0723	plastoquinol--plastocyanin reductase activity
BI317_10710	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BI317_10715	COG2857	Cytochrome c1
BI317_10725	COG0625	glutathione transferase activity
BI317_10730	COG2969	positive regulation of protein catabolic process
BI317_10740	COG1201	RNA secondary structure unwinding
BI317_10750	COG0840	transmembrane signaling receptor activity
BI317_10755	COG0835	chemotaxis
BI317_10760	COG2199	diguanylate cyclase activity
BI317_10780	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BI317_10800	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BI317_10805	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BI317_10805	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BI317_10815	COG0860	N-Acetylmuramoyl-L-alanine amidase
BI317_10820	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BI317_10840	COG1028	Short-chain dehydrogenase reductase Sdr
BI317_10845	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BI317_10850	COG0501	Belongs to the peptidase M48B family
BI317_10860	COG3300	MHYT domain
BI317_10860	COG5001	Diguanylate cyclase
BI317_10865	COG2081	HI0933 family
BI317_10870	COG4681	YaeQ
BI317_10885	COG0625	glutathione transferase activity
BI317_10895	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BI317_10900	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BI317_10905	COG0513	Belongs to the DEAD box helicase family
BI317_10920	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BI317_10930	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BI317_10935	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BI317_10940	COG0259	pyridoxamine-phosphate oxidase activity
BI317_10955	COG1842	Phage shock protein A
BI317_10980	COG0754	glutathionylspermidine amidase activity
BI317_10985	COG2814	Major facilitator Superfamily
BI317_11040	COG0531	amino acid
BI317_11045	COG2197	response regulator
BI317_11060	COG1113	amino acid transport
BI317_11070	COG1271	oxidase subunit
BI317_11075	COG1294	oxidase, subunit
BI317_11085	COG2239	Acts as a magnesium transporter
BI317_11090	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BI317_11095	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BI317_11115	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BI317_11130	COG1137	ATPase activity
BI317_11135	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BI317_11145	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BI317_11155	COG0271	Belongs to the BolA IbaG family
BI317_11160	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BI317_11190	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BI317_11205	COG0628	permease
BI317_11235	COG0483	inositol monophosphate 1-phosphatase activity
BI317_11250	COG3300	MHYT domain
BI317_11250	COG5001	Diguanylate cyclase
BI317_11255	COG1509	lysine 2,3-aminomutase activity
BI317_11270	COG0402	S-adenosylhomocysteine deaminase activity
BI317_11275	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BI317_11340	COG4302	ethanolamine ammonia-lyase activity
BI317_11345	COG4303	Ethanolamine ammonia lyase large subunit
BI317_11360	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BI317_11370	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BI317_11380	COG2166	iron-sulfur cluster assembly
BI317_11390	COG0215	cysteine-tRNA ligase activity
BI317_11400	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BI317_11405	COG0137	argininosuccinate synthase activity
BI317_11415	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BI317_11445	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BI317_11490	COG4988	ABC transporter
BI317_11495	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BI317_11535	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
BI317_11560	COG0436	Aminotransferase
BI317_11565	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BI317_11580	COG1187	pseudouridine synthase activity
BI317_11585	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BI317_11590	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BI317_11595	COG2350	Protein conserved in bacteria
BI317_11620	COG1653	transport
BI317_11625	COG1175	transmembrane transport
BI317_11630	COG0395	ABC-type sugar transport system, permease component
BI317_11655	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BI317_11660	COG2957	Belongs to the agmatine deiminase family
BI317_11670	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BI317_11675	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BI317_11685	COG0776	regulation of translation
BI317_11695	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BI317_11700	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BI317_11715	COG0475	glutathione-regulated potassium exporter activity
BI317_11715	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BI317_11725	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BI317_11755	COG3039	Transposase
BI317_11765	COG2801	Transposase and inactivated derivatives
BI317_11785	COG1914	H( )-stimulated, divalent metal cation uptake system
BI317_11790	COG1321	iron dependent repressor
BI317_11795	COG0590	tRNA wobble adenosine to inosine editing
BI317_11800	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BI317_11805	COG0668	transmembrane transport
BI317_11830	COG1028	Short-chain dehydrogenase reductase Sdr
BI317_11835	COG1183	phosphatidylcholine synthase activity
BI317_11845	COG3243	poly(R)-hydroxyalkanoic acid synthase
BI317_11870	COG2183	response to ionizing radiation
BI317_11875	COG2205	protein histidine kinase activity
BI317_11875	COG5002	protein histidine kinase activity
BI317_11875	COG0784	Response regulator, receiver
BI317_11940	COG2801	Transposase and inactivated derivatives
BI317_11945	COG2963	transposase activity
BI317_11950	COG0800	Aldolase
BI317_11955	COG0129	dihydroxy-acid dehydratase activity
BI317_11960	COG0363	glucosamine-6-phosphate deaminase activity
BI317_11965	COG0837	glucose binding
BI317_11970	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BI317_11980	COG0354	folic acid binding
BI317_11990	COG2009	succinate dehydrogenase
BI317_11995	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BI317_12010	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BI317_12015	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BI317_12025	COG4591	ABC-type transport system involved in lipoprotein release permease component
BI317_12030	COG1136	(ABC) transporter
BI317_12045	COG0811	peptide transport
BI317_12055	COG1132	(ABC) transporter
BI317_12060	COG1663	tetraacyldisaccharide 4'-kinase activity
BI317_12070	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BI317_12075	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BI317_12115	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BI317_12145	COG1530	ribonuclease E activity
BI317_12155	COG0428	transporter
BI317_12230	COG0428	transporter
BI317_12240	COG2154	pterin-4-alpha-carbinolamine dehydratase
BI317_12375	COG2963	transposase activity
BI317_12380	COG3039	Transposase
BI317_12385	COG2801	Transposase and inactivated derivatives
BI317_12420	COG2197	response regulator
BI317_12425	COG4191	Histidine kinase
BI317_12430	COG3781	membrane
BI317_12460	COG2205	protein histidine kinase activity
BI317_12465	COG0784	Response regulator, receiver
BI317_12465	COG4191	Histidine kinase
BI317_12495	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BI317_12535	COG5001	Diguanylate cyclase
BI317_12550	COG3685	Protein conserved in bacteria
BI317_12560	COG0579	oxidoreductase
BI317_12570	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BI317_12580	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
BI317_12600	COG0243	molybdopterin cofactor binding
BI317_12610	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BI317_12615	COG2223	nitrite transmembrane transporter activity
BI317_12625	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BI317_12635	COG1648	precorrin-2 dehydrogenase activity
BI317_12635	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BI317_12645	COG0746	molybdenum cofactor guanylyltransferase activity
BI317_12650	COG0303	'Molybdopterin
BI317_12660	COG0708	Exodeoxyribonuclease III
BI317_12670	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BI317_12675	COG0303	'Molybdopterin
BI317_12680	COG1160	GTP binding
BI317_12685	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BI317_12705	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BI317_12710	COG0105	UTP biosynthetic process
BI317_12720	COG1250	3-hydroxyacyl-CoA dehydrogenase
BI317_12720	COG1024	Enoyl-CoA hydratase
BI317_12725	COG0183	Belongs to the thiolase family
BI317_12730	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BI317_12735	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BI317_12750	COG1674	ftsk spoiiie
BI317_12755	COG0492	ferredoxin-NADP+ reductase activity
BI317_12765	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BI317_12770	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BI317_12775	COG0542	response to heat
BI317_12780	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BI317_12790	COG0482	sulfurtransferase activity
BI317_12795	COG2915	High frequency lysogenization protein hflD homolog
BI317_12825	COG3293	Transposase
BI317_12850	COG4191	Histidine kinase
BI317_12870	COG0784	Response regulator, receiver
BI317_12870	COG0835	chemotaxis
BI317_12880	COG1558	bacterial-type flagellum-dependent cell motility
BI317_12885	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BI317_12890	COG1749	Flagellar hook protein flgE
BI317_12895	COG4787	bacterial-type flagellum-dependent cell motility
BI317_12910	COG4786	Flagellar basal body rod
BI317_12925	COG1705	Flagellar rod assembly protein muramidase FlgJ
BI317_12925	COG3951	Flagellar rod assembly protein muramidase FlgJ
BI317_12940	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BI317_12945	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BI317_12975	COG2201	protein-glutamate methylesterase activity
BI317_12995	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BI317_13000	COG1028	Short-chain dehydrogenase reductase Sdr
BI317_13005	COG1028	Short-chain dehydrogenase reductase Sdr
BI317_13035	COG3039	Transposase
BI317_13045	COG3039	Transposase
BI317_13060	COG1677	Flagellar hook-basal body complex protein FliE
BI317_13110	COG3190	flagellar
BI317_13120	COG1987	bacterial-type flagellum assembly
BI317_13130	COG5001	Diguanylate cyclase
BI317_13130	COG3300	MHYT domain
BI317_13160	COG0455	bacterial-type flagellum organization
BI317_13180	COG0643	Histidine kinase
BI317_13180	COG2198	Histidine kinase
BI317_13195	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BI317_13205	COG1192	Involved in chromosome partitioning
BI317_13210	COG0835	chemotaxis
BI317_13220	COG0745	RESPONSE REGULATOR receiver
BI317_13225	COG2198	Histidine kinase
BI317_13225	COG0643	Histidine kinase
BI317_13240	COG0840	transmembrane signaling receptor activity
BI317_13240	COG0840	transmembrane signaling receptor activity
BI317_13245	COG0840	transmembrane signaling receptor activity
BI317_13250	COG0840	transmembrane signaling receptor activity
BI317_13255	COG0840	transmembrane signaling receptor activity
BI317_13260	COG0840	transmembrane signaling receptor activity
BI317_13265	COG0840	transmembrane signaling receptor activity
BI317_13270	COG0840	transmembrane signaling receptor activity
BI317_13275	COG0840	transmembrane signaling receptor activity
BI317_13295	COG0835	chemotaxis
BI317_13305	COG0840	transmembrane signaling receptor activity
BI317_13320	COG2201	protein-glutamate methylesterase activity
BI317_13335	COG2267	carboxylic ester hydrolase activity
BI317_13365	COG0318	PFAM AMP-dependent synthetase and ligase
BI317_13375	COG2198	Histidine kinase
BI317_13375	COG2205	protein histidine kinase activity
BI317_13375	COG0784	Response regulator, receiver
BI317_13390	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BI317_13420	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BI317_13430	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BI317_13435	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BI317_13445	COG0505	Belongs to the CarA family
BI317_13455	COG2258	MOSC domain
BI317_13460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BI317_13480	COG1024	Enoyl-CoA hydratase
BI317_13495	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BI317_13515	COG0277	FAD linked oxidase domain protein
BI317_13520	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BI317_13535	COG0531	amino acid
BI317_13540	COG0531	amino acid
BI317_13565	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
BI317_13585	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BI317_13585	COG0140	phosphoribosyl-ATP diphosphatase activity
BI317_13590	COG0107	imidazoleglycerol-phosphate synthase activity
BI317_13610	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BI317_13615	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BI317_13640	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BI317_13665	COG0527	aspartate kinase activity
BI317_13665	COG0460	homoserine dehydrogenase
BI317_13670	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
BI317_13680	COG3039	Transposase
BI317_13715	COG0726	polysaccharide deacetylase
BI317_13715	COG1649	PFAM Uncharacterised BCR, COG1649
BI317_13725	COG2963	transposase activity
BI317_13730	COG2801	Transposase and inactivated derivatives
BI317_13765	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
BI317_13765	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
BI317_13775	COG3039	Transposase
BI317_13785	COG2963	transposase activity
BI317_13790	COG2801	Transposase and inactivated derivatives
BI317_13850	COG0210	DNA helicase
BI317_13855	COG3039	Transposase
BI317_13885	COG2801	Transposase and inactivated derivatives
BI317_13890	COG2963	transposase activity
BI317_13940	COG2003	Belongs to the UPF0758 family
BI317_13980	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BI317_14025	COG1012	belongs to the aldehyde dehydrogenase family
BI317_14040	COG0167	dihydroorotate dehydrogenase activity
BI317_14045	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BI317_14050	COG0697	spore germination
BI317_14065	COG0671	phosphoesterase, PA-phosphatase related
BI317_14070	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BI317_14080	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BI317_14090	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BI317_14095	COG2203	Gaf domain
BI317_14095	COG5001	Diguanylate cyclase
BI317_14095	COG3706	GGDEF domain
BI317_14095	COG4251	negative regulation of phosphorylation
BI317_14105	COG1472	Belongs to the glycosyl hydrolase 3 family
BI317_14140	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BI317_14145	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BI317_14150	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BI317_14155	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BI317_14175	COG0860	N-Acetylmuramoyl-L-alanine amidase
BI317_14195	COG0477	Major facilitator Superfamily
BI317_14200	COG2115	Belongs to the xylose isomerase family
BI317_14205	COG1070	Carbohydrate kinase
BI317_14215	COG1501	Belongs to the glycosyl hydrolase 31 family
BI317_14250	COG0800	Aldolase
BI317_14275	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BI317_14285	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BI317_14300	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BI317_14305	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BI317_14320	COG0352	thiamine-phosphate diphosphorylase activity
BI317_14320	COG0351	phosphomethylpyrimidine kinase
BI317_14345	COG1741	Belongs to the pirin family
BI317_14360	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BI317_14365	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BI317_14370	COG2137	regulation of response to DNA damage stimulus
BI317_14385	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BI317_14390	COG4771	TonB-dependent receptor
BI317_14395	COG1546	Belongs to the CinA family
BI317_14400	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BI317_14405	COG1923	regulation of RNA biosynthetic process
BI317_14410	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BI317_14415	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BI317_14420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BI317_14425	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BI317_14430	COG1534	Rna-binding protein
BI317_14445	COG1238	metal cluster binding
BI317_14450	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BI317_14455	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BI317_14460	COG2840	Smr protein MutS2
BI317_14485	COG0148	phosphopyruvate hydratase activity
BI317_14500	COG0504	CTP synthase activity
BI317_14540	COG1253	flavin adenine dinucleotide binding
BI317_14555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BI317_14560	COG0477	Major facilitator Superfamily
BI317_14575	COG1132	(ABC) transporter
BI317_14605	COG0438	transferase activity, transferring glycosyl groups
BI317_14610	COG0297	glycogen (starch) synthase activity
BI317_14615	COG2264	protein methyltransferase activity
BI317_14645	COG2244	polysaccharide biosynthetic process
BI317_14695	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BI317_14705	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
BI317_14715	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BI317_14755	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BI317_14785	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BI317_14790	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BI317_14795	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BI317_14800	COG2080	2 iron, 2 sulfur cluster binding
BI317_14820	COG0629	single-stranded DNA binding
BI317_14825	COG0142	geranyltranstransferase activity
BI317_14845	COG0527	aspartate kinase activity
BI317_14850	COG0384	phenazine biosynthesis protein PhzF
BI317_14855	COG0384	phenazine biosynthesis protein PhzF
BI317_14865	COG1764	response to oxidative stress
BI317_14875	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BI317_14880	COG1678	Uncharacterized ACR, COG1678
BI317_14885	COG0519	Catalyzes the synthesis of GMP from XMP
BI317_14910	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BI317_14925	COG4942	peptidase
BI317_14950	COG1959	2 iron, 2 sulfur cluster binding
BI317_14955	COG0719	Fe-S assembly protein
BI317_14960	COG0396	ATPase activity
BI317_14965	COG0719	Fe-S assembly protein
BI317_14970	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BI317_14975	COG0456	acetyltransferase
BI317_14990	COG4774	siderophore transport
BI317_14995	COG3128	pkhd-type hydroxylase
BI317_15020	COG1477	protein flavinylation
BI317_15025	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BI317_15035	COG1555	photosystem II stabilization
BI317_15040	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BI317_15050	COG3178	'Phosphotransferase
BI317_15055	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BI317_15090	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BI317_15105	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
BI317_15110	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BI317_15115	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BI317_15120	COG3115	cell septum assembly
BI317_15145	COG0316	Belongs to the HesB IscA family
BI317_15155	COG0017	Asparaginyl-tRNA synthetase
BI317_15170	COG2808	Putative FMN-binding domain
BI317_15175	COG0288	reversible hydration of carbon dioxide
BI317_15195	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BI317_15200	COG2925	Exonuclease
BI317_15225	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BI317_15285	COG1024	Enoyl-CoA hydratase
BI317_15295	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BI317_15300	COG3039	Transposase
BI317_15305	COG3039	Transposase
BI317_15315	COG3293	Transposase
BI317_15320	COG0659	secondary active sulfate transmembrane transporter activity
BI317_15345	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BI317_15350	COG0573	inorganic phosphate transmembrane transporter activity
BI317_15355	COG0581	inorganic phosphate transmembrane transporter activity
BI317_15360	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BI317_15365	COG0704	Plays a role in the regulation of phosphate uptake
BI317_15375	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BI317_15380	COG3706	GGDEF domain
BI317_15385	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BI317_15395	COG0557	exoribonuclease II activity
BI317_15410	COG3039	Transposase
BI317_15415	COG1960	acyl-CoA dehydrogenase activity
BI317_15430	COG0646	methionine synthase
BI317_15430	COG1410	methionine synthase
BI317_15445	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BI317_15485	COG0386	Belongs to the glutathione peroxidase family
BI317_15495	COG1725	Transcriptional regulator
BI317_15500	COG1131	(ABC) transporter
BI317_15530	COG1253	flavin adenine dinucleotide binding
BI317_15550	COG2850	peptidyl-arginine hydroxylation
BI317_15585	COG1132	(ABC) transporter
BI317_15590	COG0583	DNA-binding transcription factor activity
BI317_15595	COG2274	protein secretion by the type I secretion system
BI317_15620	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BI317_15635	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BI317_15640	COG1420	regulation of RNA biosynthetic process
BI317_15645	COG0497	DNA recombination
BI317_15655	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BI317_15670	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BI317_15685	COG0582	viral genome integration into host DNA
BI317_15755	COG1196	nuclear chromosome segregation
BI317_15915	COG0305	Participates in initiation and elongation during chromosome replication
BI317_15940	COG4197	protein conserved in bacteria, prophage-related
BI317_16085	COG3706	GGDEF domain
BI317_16095	COG3706	GGDEF domain
BI317_16115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BI317_16130	COG0583	DNA-binding transcription factor activity
BI317_16140	COG2155	Conserved Protein
BI317_16180	COG1132	(ABC) transporter
BI317_16195	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BI317_16200	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BI317_16215	COG3706	GGDEF domain
BI317_16215	COG0745	RESPONSE REGULATOR receiver
BI317_16220	COG1187	pseudouridine synthase activity
BI317_16225	COG5001	Diguanylate cyclase
BI317_16225	COG5002	protein histidine kinase activity
BI317_16235	COG1595	DNA-templated transcription, initiation
BI317_16255	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BI317_16330	COG1404	Belongs to the peptidase S8 family
BI317_16340	COG1404	Belongs to the peptidase S8 family
BI317_16345	COG0667	Aldo Keto reductase
BI317_16350	COG2814	Major facilitator Superfamily
BI317_16355	COG0583	DNA-binding transcription factor activity
BI317_16385	COG0667	Aldo Keto reductase
BI317_16390	COG1309	transcriptional regulator
BI317_16395	COG1538	Outer membrane efflux protein
BI317_16400	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BI317_16420	COG0735	belongs to the Fur family
BI317_16425	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BI317_16450	COG4452	Inner membrane protein CreD
BI317_16460	COG2205	protein histidine kinase activity
BI317_16465	COG0745	RESPONSE REGULATOR receiver
BI317_16470	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BI317_16485	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BI317_16495	COG2198	Histidine kinase
BI317_16495	COG0643	Histidine kinase
BI317_16500	COG0840	transmembrane signaling receptor activity
BI317_16505	COG0835	chemotaxis
BI317_16515	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BI317_16525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BI317_16530	COG3590	peptidase
BI317_16545	COG1515	deoxyribonuclease V activity
BI317_16550	COG1741	Belongs to the pirin family
BI317_16565	COG1741	Belongs to the pirin family
BI317_16570	COG1966	Carbon starvation protein
BI317_16575	COG2879	small protein
BI317_16590	COG4191	Histidine kinase
BI317_16590	COG0784	Response regulator, receiver
BI317_16595	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
BI317_16600	COG5002	protein histidine kinase activity
BI317_16600	COG2205	protein histidine kinase activity
BI317_16600	COG0784	Response regulator, receiver
BI317_16620	COG0840	transmembrane signaling receptor activity
BI317_16705	COG3039	Transposase
BI317_16745	COG2003	Belongs to the UPF0758 family
BI317_16775	COG3293	Transposase
BI317_16790	COG0758	DNA mediated transformation
BI317_16850	COG2815	serine threonine protein kinase
BI317_16850	COG0515	serine threonine protein kinase
BI317_16915	COG0210	DNA helicase
BI317_16920	COG1752	Esterase of the alpha-beta hydrolase superfamily
BI317_16950	COG0583	DNA-binding transcription factor activity
BI317_16960	COG3293	Transposase
BI317_16965	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BI317_16980	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BI317_16985	COG1605	Chorismate mutase
BI317_16985	COG0077	Prephenate dehydratase
BI317_16990	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BI317_16995	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BI317_17000	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BI317_17035	COG1228	amidohydrolase
BI317_17040	COG2986	histidine ammonia-lyase
BI317_17050	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BI317_17060	COG0477	Major facilitator Superfamily
BI317_17090	COG2205	protein histidine kinase activity
BI317_17090	COG2198	Histidine kinase
BI317_17090	COG0784	Response regulator, receiver
BI317_17095	COG2353	YceI-like domain
BI317_17100	COG3038	cytochrome b561
BI317_17110	COG1278	Cold shock
BI317_17120	COG1760	l-serine dehydratase
BI317_17130	COG0460	homoserine dehydrogenase
BI317_17130	COG0527	aspartate kinase activity
BI317_17135	COG0626	cystathionine gamma-synthase activity
BI317_17140	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BI317_17150	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BI317_17155	COG1272	protein, Hemolysin III
BI317_17160	COG2982	Protein involved in outer membrane biogenesis
BI317_17170	COG0516	GMP reductase activity
BI317_17170	COG0517	IMP dehydrogenase activity
BI317_17175	COG0463	Glycosyl transferase, family 2
BI317_17180	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BI317_17185	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BI317_17195	COG4206	TonB-dependent receptor
BI317_17200	COG1309	transcriptional regulator
BI317_17205	COG2267	carboxylic ester hydrolase activity
BI317_17210	COG1960	acyl-CoA dehydrogenase activity
BI317_17245	COG0509	glycine decarboxylation via glycine cleavage system
BI317_17250	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BI317_17255	COG1742	UPF0060 membrane protein
BI317_17260	COG3956	TIGRFAM MazG family protein
BI317_17265	COG1218	3'(2'),5'-bisphosphate nucleotidase
BI317_17270	COG0494	nUDIX hydrolase
BI317_17280	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BI317_17300	COG3858	chitin binding
BI317_17300	COG1388	LysM domain
BI317_17320	COG1472	Belongs to the glycosyl hydrolase 3 family
BI317_17345	COG0531	amino acid
BI317_17355	COG1486	melibiose metabolic process
BI317_17365	COG3537	Alpha-1,2-mannosidase
BI317_17380	COG3039	Transposase
BI317_17395	COG2963	transposase activity
BI317_17455	COG3142	Participates in the control of copper homeostasis
BI317_17460	COG1446	asparaginase
BI317_17465	COG2304	oxidoreductase activity
BI317_17470	COG1595	DNA-templated transcription, initiation
BI317_17495	COG2201	protein-glutamate methylesterase activity
BI317_17505	COG0840	transmembrane signaling receptor activity
BI317_17510	COG0835	chemotaxis
BI317_17525	COG0189	ligase activity
BI317_17540	COG1199	ATP-dependent helicase activity
BI317_17550	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BI317_17565	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BI317_17575	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BI317_17580	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
BI317_17600	COG0837	glucose binding
BI317_17610	COG1643	Atp-dependent helicase
BI317_17615	COG0783	Belongs to the Dps family
BI317_17620	COG0514	ATP-dependent DNA helicase (RecQ)
BI317_17635	COG1187	pseudouridine synthase activity
BI317_17670	COG3920	Histidine kinase
BI317_17715	COG0667	Aldo Keto reductase
BI317_17720	COG0602	queuosine metabolic process
BI317_17730	COG2885	chlorophyll binding
BI317_17745	COG0848	biopolymer transport protein
BI317_17755	COG0824	Thioesterase
BI317_17805	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BI317_17825	COG0477	Major facilitator Superfamily
BI317_17865	COG0488	(ABC) transporter
BI317_17895	COG4651	solute:proton antiporter activity
BI317_17895	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BI317_17905	COG4772	TonB-dependent receptor
BI317_17915	COG4264	IucA IucC family
BI317_17925	COG4264	IucA IucC family
BI317_17930	COG0019	diaminopimelate decarboxylase activity
BI317_17945	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BI317_17955	COG4206	TonB-dependent receptor
BI317_17965	COG0542	response to heat
BI317_17970	COG1116	anion transmembrane transporter activity
BI317_17975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BI317_17980	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BI317_17985	COG0667	Aldo Keto reductase
BI317_17995	COG4771	TonB-dependent receptor
BI317_18045	COG1877	trehalose-phosphatase activity
BI317_18050	COG3387	PFAM Glycoside hydrolase 15-related
BI317_18065	COG0840	transmembrane signaling receptor activity
BI317_18070	COG3011	Protein conserved in bacteria
BI317_18085	COG0564	pseudouridine synthase activity
BI317_18090	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BI317_18100	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BI317_18100	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BI317_18135	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BI317_18140	COG0045	succinate-CoA ligase (ADP-forming) activity
BI317_18170	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BI317_18200	COG0745	RESPONSE REGULATOR receiver
BI317_18205	COG0189	ligase activity
BI317_18240	COG0840	transmembrane signaling receptor activity
BI317_18245	COG1238	metal cluster binding
BI317_18255	COG2963	transposase activity
BI317_18260	COG2801	Transposase and inactivated derivatives
BI317_18305	COG2801	Transposase and inactivated derivatives
BI317_18310	COG2963	transposase activity
BI317_18330	COG2801	Transposase and inactivated derivatives
BI317_18335	COG2963	transposase activity
BI317_18340	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BI317_18395	COG2801	Transposase and inactivated derivatives
BI317_18400	COG2963	transposase activity
BI317_18410	COG2963	transposase activity
BI317_18415	COG2801	Transposase and inactivated derivatives
BI317_18490	COG3039	Transposase
BI317_18505	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BI317_18530	COG3077	Addiction module antitoxin, RelB DinJ family
BI317_18560	COG0583	DNA-binding transcription factor activity
BI317_18565	COG1396	sequence-specific DNA binding
BI317_18595	COG2963	transposase activity
BI317_18600	COG2801	Transposase and inactivated derivatives
BI317_18635	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BI317_18640	COG3273	potassium ion transport
BI317_18640	COG0471	metal ion transport
BI317_18670	COG1609	Transcriptional regulator
BI317_18680	COG3250	beta-galactosidase activity
BI317_18685	COG4948	Mandelate Racemase Muconate Lactonizing
BI317_18695	COG2272	Belongs to the type-B carboxylesterase lipase family
BI317_18700	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BI317_18720	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BI317_18725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BI317_18730	COG2895	sulfate adenylyltransferase (ATP) activity
BI317_18730	COG0529	Catalyzes the synthesis of activated sulfate
BI317_18745	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BI317_18770	COG2205	protein histidine kinase activity
BI317_18770	COG2198	Histidine kinase
BI317_18770	COG0784	Response regulator, receiver
BI317_18785	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BI317_18785	COG1648	precorrin-2 dehydrogenase activity
BI317_18800	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BI317_18805	COG3588	fructose-bisphosphate aldolase
BI317_18815	COG0469	pyruvate kinase activity
BI317_18825	COG0126	phosphoglycerate kinase activity
BI317_18845	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BI317_18860	COG3047	cAMP biosynthetic process
BI317_18870	COG3453	Protein conserved in bacteria
BI317_18870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BI317_18875	COG0725	ABC transporter, periplasmic molybdate-binding protein
BI317_18880	COG4149	molybdate abc transporter
BI317_18885	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BI317_18900	COG3682	Transcriptional regulator
BI317_18920	COG1376	ErfK ybiS ycfS ynhG family protein
BI317_18935	COG1028	Short-chain dehydrogenase reductase Sdr
BI317_18940	COG0583	DNA-binding transcription factor activity
BI317_18945	COG4773	Receptor
BI317_18960	COG1301	dicarboxylic acid transport
BI317_18995	COG0714	Associated with various cellular activities
BI317_19025	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BI317_19050	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BI317_19060	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BI317_19065	COG1758	RNA polymerase activity
BI317_19075	COG1561	YicC-like family, N-terminal region
BI317_19080	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BI317_19085	COG0346	lactoylglutathione lyase activity
BI317_19095	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BI317_19110	COG0006	proline dipeptidase activity
BI317_19115	COG0006	proline dipeptidase activity
BI317_19140	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BI317_19160	COG2912	Transglutaminase-like superfamily
BI317_19165	COG1773	rubredoxin
BI317_19170	COG0352	thiamine-phosphate diphosphorylase activity
BI317_19185	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BI317_19195	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
BI317_19200	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BI317_19230	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BI317_19235	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BI317_19255	COG1028	Short-chain dehydrogenase reductase Sdr
BI317_19265	COG0671	phosphoesterase, PA-phosphatase related
BI317_19275	COG3781	membrane
BI317_19285	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BI317_19290	COG0563	adenylate kinase activity
BI317_19310	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BI317_19320	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BI317_19340	COG3710	Transcriptional regulator
BI317_19355	COG1506	peptidase
BI317_19355	COG4946	Tricorn protease homolog
BI317_19355	COG0823	Involved in the tonB-independent uptake of proteins
BI317_19360	COG0840	transmembrane signaling receptor activity
BI317_19390	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BI317_19395	COG0473	3-isopropylmalate dehydrogenase activity
BI317_19400	COG2226	methyltransferase
BI317_19405	COG0066	3-isopropylmalate dehydratase activity
BI317_19410	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BI317_19430	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BI317_19435	COG1538	Outer membrane efflux protein
BI317_19445	COG1519	Transferase
BI317_19450	COG1560	Kdo2-lipid A biosynthetic process
BI317_19475	COG0280	phosphate acetyltransferase
BI317_19475	COG0281	malic enzyme
BI317_19490	COG4191	Histidine kinase
BI317_19505	COG2197	response regulator
BI317_19510	COG1840	ABC-type Fe3 transport system, periplasmic component
BI317_19515	COG0642	Histidine kinase
BI317_19530	COG2851	Citrate transporter
BI317_19535	COG1028	Short-chain dehydrogenase reductase Sdr
BI317_19540	COG1609	Transcriptional regulator
BI317_19545	COG2211	Major facilitator Superfamily
BI317_19595	COG3039	Transposase
BI317_19640	COG2963	transposase activity
BI317_19660	COG3293	Transposase
BI317_19675	COG4773	Receptor
BI317_19680	COG0726	polysaccharide deacetylase
BI317_19685	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BI317_19705	COG0402	S-adenosylhomocysteine deaminase activity
BI317_19735	COG1307	EDD domain protein, DegV family
BI317_19740	COG1307	EDD domain protein, DegV family
BI317_19755	COG3293	Transposase
BI317_19765	COG0697	spore germination
BI317_19775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BI317_19815	COG0745	RESPONSE REGULATOR receiver
BI317_19820	COG2205	protein histidine kinase activity
BI317_19830	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BI317_19845	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BI317_19855	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BI317_19865	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
BI317_19905	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BI317_19910	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BI317_19915	COG1609	Transcriptional regulator
BI317_19940	COG3250	beta-galactosidase activity
BI317_19965	COG3156	type II secretion system protein K
BI317_19990	COG1459	type II secretion system
BI317_20040	COG1028	Short-chain dehydrogenase reductase Sdr
BI317_20045	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BI317_20050	COG4191	Histidine kinase
BI317_20055	COG0784	Response regulator, receiver
BI317_20060	COG4251	negative regulation of phosphorylation
BI317_20065	COG2823	Periplasmic or secreted lipoprotein
BI317_20070	COG0673	inositol 2-dehydrogenase activity
BI317_20075	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BI317_20110	COG1051	belongs to the nudix hydrolase family
BI317_20110	COG1056	cytidyltransferase-related domain
BI317_20130	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BI317_20135	COG0321	lipoyl(octanoyl) transferase activity
BI317_20140	COG2921	Belongs to the UPF0250 family
BI317_20150	COG1686	Belongs to the peptidase S11 family
BI317_20155	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BI317_20160	COG2951	lytic endotransglycosylase activity
BI317_20170	COG0772	Belongs to the SEDS family
BI317_20180	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BI317_20185	COG1792	Involved in formation and maintenance of cell shape
BI317_20190	COG1077	Cell shape determining protein MreB Mrl
BI317_20200	COG3284	Transcriptional regulator
BI317_20255	COG0308	aminopeptidase N
BI317_20260	COG5001	Diguanylate cyclase
BI317_20260	COG3300	MHYT domain
BI317_20265	COG2226	methyltransferase
BI317_20295	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BI317_20300	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BI317_20305	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BI317_20310	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BI317_20320	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BI317_20330	COG2832	Protein of unknown function (DUF454)
BI317_20345	COG3039	Transposase
BI317_20365	COG1505	serine-type exopeptidase activity
BI317_20390	COG0181	hydroxymethylbilane synthase activity
BI317_20400	COG3275	phosphorelay sensor kinase activity
BI317_20435	COG3706	GGDEF domain
BI317_20440	COG0659	secondary active sulfate transmembrane transporter activity
BI317_20445	COG5297	Belongs to the glycosyl hydrolase family 6
BI317_20445	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BI317_20515	COG3507	Belongs to the glycosyl hydrolase 43 family
BI317_20525	COG0598	Magnesium transport protein CorA
BI317_20530	COG1113	amino acid transport
BI317_20550	COG0697	spore germination
BI317_20575	COG3706	GGDEF domain
BI317_20620	COG0435	Glutathione S-transferase
BI317_20750	COG0210	DNA helicase
BI317_20845	COG1802	Transcriptional regulator
BI317_20860	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
BI317_20880	COG3052	prosthetic group binding
BI317_20905	COG2353	YceI-like domain
BI317_20910	COG0778	Nitroreductase
BI317_20930	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BI317_20935	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BI317_20965	COG3712	iron ion homeostasis
BI317_20990	COG3293	Transposase
BI317_21000	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BI317_21005	COG3550	peptidyl-serine autophosphorylation
BI317_21020	COG3293	Transposase
BI317_21050	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BI317_21055	COG2356	endonuclease I
BI317_21060	COG1324	tolerance protein
BI317_21070	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BI317_21075	COG0511	ligase activity, forming carbon-carbon bonds
BI317_21085	COG0439	Biotin carboxylase
BI317_21100	COG2264	protein methyltransferase activity
BI317_21125	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BI317_21135	COG3039	Transposase
BI317_21160	COG0138	bifunctional purine biosynthesis protein purh
BI317_21165	COG0151	Belongs to the GarS family
BI317_21170	COG1289	transmembrane transporter activity
BI317_21175	COG2814	Major facilitator Superfamily
BI317_21195	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BI317_21200	COG2816	NAD+ diphosphatase activity
BI317_21210	COG0316	Belongs to the HesB IscA family
BI317_21270	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BI317_21280	COG2076	Multidrug Resistance protein
BI317_21290	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BI317_21300	COG0134	indole-3-glycerol-phosphate synthase activity
BI317_21305	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BI317_21320	COG0840	transmembrane signaling receptor activity
BI317_21330	COG3293	Transposase
BI317_21345	COG3550	peptidyl-serine autophosphorylation
BI317_21350	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BI317_21360	COG3293	Transposase
BI317_21430	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BI317_21500	COG2963	transposase activity
BI317_21505	COG2801	Transposase and inactivated derivatives
BI317_21515	COG2267	carboxylic ester hydrolase activity
BI317_21555	COG1597	lipid kinase activity
BI317_21575	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BI317_21640	COG2111	Na H antiporter
BI317_21640	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BI317_21645	COG1006	Multisubunit Na H antiporter MnhC subunit
BI317_21650	COG0651	ATP synthesis coupled electron transport
BI317_21660	COG2212	antiporter activity
BI317_21665	COG1320	monovalent cation:proton antiporter activity
BI317_21685	COG2852	Protein conserved in bacteria
BI317_21705	COG3104	oligopeptide transport
BI317_21720	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BI317_21735	COG0508	dehydrogenase complex catalyzes the overall conversion of
BI317_21745	COG0513	Belongs to the DEAD box helicase family
BI317_21755	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BI317_21795	COG1028	Short-chain dehydrogenase reductase Sdr
BI317_21800	COG0702	epimerase
BI317_21825	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BI317_21830	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BI317_21835	COG0297	glycogen (starch) synthase activity
BI317_21840	COG3706	GGDEF domain
BI317_21850	COG2354	Protein conserved in bacteria
BI317_21855	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BI317_21860	COG1368	sulfuric ester hydrolase activity
BI317_21870	COG1511	domain protein
BI317_21870	COG3264	Mechanosensitive ion channel
BI317_21890	COG3590	peptidase
BI317_21895	COG3293	Transposase
BI317_21905	COG0582	viral genome integration into host DNA
BI317_21930	COG1040	competence protein
BI317_21935	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BI317_21940	COG0156	8-amino-7-oxononanoate synthase activity
BI317_22010	COG1414	Transcriptional regulator
BI317_22020	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BI317_22025	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BI317_22040	COG3485	protocatechuate 3,4-dioxygenase
BI317_22050	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BI317_22055	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BI317_22085	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BI317_22090	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BI317_22145	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BI317_22155	COG0129	dihydroxy-acid dehydratase activity
BI317_22185	COG2963	transposase activity
BI317_22190	COG2801	Transposase and inactivated derivatives
BI317_22205	COG2801	Transposase and inactivated derivatives
BI317_22210	COG2963	transposase activity
BI317_22255	COG2963	transposase activity
BI317_22260	COG2801	Transposase and inactivated derivatives
BI317_22270	COG1733	regulation of RNA biosynthetic process
BI317_22275	COG0702	epimerase
BI317_22290	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BI317_22305	COG0583	DNA-binding transcription factor activity
BI317_22310	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BI317_22315	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BI317_22350	COG1902	pentaerythritol trinitrate reductase activity
BI317_22355	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BI317_22390	COG2814	Major facilitator Superfamily
BI317_22395	COG0583	DNA-binding transcription factor activity
BI317_22410	COG0084	hydrolase, TatD family'
BI317_22430	COG2252	PERMEase
BI317_22470	COG3293	Transposase
BI317_22520	COG3039	Transposase
BI317_22525	COG3039	Transposase
BI317_22535	COG2801	Transposase and inactivated derivatives
BI317_22540	COG2963	transposase activity
BI317_22565	COG3039	Transposase
BI317_22600	COG2801	Transposase and inactivated derivatives
BI317_22605	COG2963	transposase activity
BI317_22680	COG4695	Portal protein
BI317_22715	COG2963	transposase activity
BI317_22720	COG2801	Transposase and inactivated derivatives
BI317_22755	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
BI317_22755	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BI317_22760	COG3039	Transposase
BI317_22770	COG3039	Transposase
BI317_22785	COG1487	ribonuclease activity
BI317_22790	COG1902	pentaerythritol trinitrate reductase activity
BI317_22795	COG0583	DNA-binding transcription factor activity
BI317_22800	COG1309	transcriptional regulator
BI317_22815	COG4977	sequence-specific DNA binding
BI317_22835	COG0659	secondary active sulfate transmembrane transporter activity
BI317_22865	COG0251	oxidation-reduction process
BI317_22920	COG2814	Major facilitator Superfamily
BI317_22925	COG0583	DNA-binding transcription factor activity
BI317_22945	COG1063	alcohol dehydrogenase
BI317_22960	COG1132	(ABC) transporter
BI317_22980	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BI317_22990	COG3039	Transposase
BI317_23000	COG1028	Short-chain dehydrogenase reductase Sdr
BI317_23015	COG2204	response regulator
BI317_23045	COG3546	catalase activity
BI317_23050	COG3685	Protein conserved in bacteria
BI317_23070	COG2972	Histidine kinase
BI317_23085	COG0531	amino acid
BI317_23110	COG3590	peptidase
BI317_23120	COG0667	Aldo Keto reductase
BI317_23130	COG0583	DNA-binding transcription factor activity
BI317_23140	COG3384	dioxygenase
BI317_23155	COG1573	uracil-dna glycosylase
BI317_23160	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
BI317_23175	COG0025	NhaP-type Na H and K H
BI317_23180	COG1131	(ABC) transporter
BI317_23185	COG0842	Transport permease protein
BI317_23225	COG0596	Alpha beta hydrolase
BI317_23250	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BI317_23270	COG2072	flavoprotein involved in K transport
BI317_23275	COG2351	hydroxyisourate hydrolase activity
BI317_23280	COG4807	Protein conserved in bacteria
BI317_23290	COG0840	transmembrane signaling receptor activity
BI317_23295	COG1643	Atp-dependent helicase
BI317_23310	COG1187	pseudouridine synthase activity
BI317_23325	COG2130	NADP-dependent
BI317_23330	COG0656	L-ascorbic acid biosynthetic process
BI317_23355	COG1764	response to oxidative stress
BI317_23360	COG1846	Transcriptional regulator
BI317_23375	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BI317_23385	COG0697	spore germination
BI317_23400	COG0523	cobalamin synthesis protein
BI317_23455	COG1960	acyl-CoA dehydrogenase activity
BI317_23460	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BI317_23490	COG5001	Diguanylate cyclase
BI317_23495	COG2224	Isocitrate lyase
BI317_23500	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BI317_23505	COG0583	DNA-binding transcription factor activity
BI317_23525	COG0339	signal peptide processing
BI317_23530	COG1446	asparaginase
BI317_23550	COG0564	pseudouridine synthase activity
BI317_23565	COG1181	Belongs to the D-alanine--D-alanine ligase family
BI317_23575	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BI317_23595	COG0318	PFAM AMP-dependent synthetase and ligase
BI317_23605	COG0596	Alpha beta hydrolase
BI317_23610	COG3177	Filamentation induced by cAMP protein fic
BI317_23615	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BI317_23630	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BI317_23660	COG0028	Belongs to the TPP enzyme family
BI317_23670	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BI317_23680	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BI317_23720	COG0183	Belongs to the thiolase family
BI317_23730	COG2032	superoxide dismutase activity
BI317_23735	COG2032	superoxide dismutase activity
BI317_23740	COG2204	response regulator
BI317_23745	COG3852	Histidine kinase
BI317_23750	COG0004	ammonium transporteR
BI317_23755	COG0347	Belongs to the P(II) protein family
BI317_23760	COG0174	glutamine synthetase
BI317_23775	COG1881	PFAM PEBP family protein
BI317_23810	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BI317_23820	COG2062	phosphohistidine phosphatase, SixA
BI317_23825	COG0489	protein tyrosine kinase activity
BI317_23850	COG1396	sequence-specific DNA binding
BI317_23855	COG3550	peptidyl-serine autophosphorylation
BI317_23865	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BI317_23880	COG1125	glycine betaine transport
BI317_23880	COG0517	IMP dehydrogenase activity
BI317_23895	COG1119	ATPase activity
BI317_23900	COG1752	Esterase of the alpha-beta hydrolase superfamily
BI317_23910	COG1522	sequence-specific DNA binding
BI317_23915	COG3186	Phenylalanine-4-hydroxylase
BI317_23935	COG2755	lipolytic protein G-D-S-L family
BI317_23945	COG1028	Short-chain dehydrogenase reductase Sdr
BI317_23950	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BI317_23960	COG1609	Transcriptional regulator
BI317_23965	COG3507	Belongs to the glycosyl hydrolase 43 family
BI317_23980	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BI317_24000	COG2755	lipolytic protein G-D-S-L family
BI317_24030	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BI317_24035	COG0366	Alpha amylase catalytic
BI317_24040	COG0366	Alpha amylase catalytic
BI317_24090	COG2801	Transposase and inactivated derivatives
BI317_24095	COG2963	transposase activity
BI317_24100	COG3039	Transposase
BI317_24155	COG3293	Transposase
BI317_24180	COG2207	Transcriptional regulator
BI317_24185	COG1028	Short-chain dehydrogenase reductase Sdr
BI317_24195	COG3549	Plasmid maintenance system killer
BI317_24280	COG4232	protein-disulfide reductase activity
BI317_24285	COG0210	DNA helicase
BI317_24365	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BI317_24400	COG4644	lycopene metabolic process
BI317_24445	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BI317_24450	COG0431	NADPH-dependent FMN reductase
BI317_24455	COG1393	Belongs to the ArsC family
BI317_24475	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BI317_24500	COG2132	Multicopper oxidase
BI317_24555	COG0010	Belongs to the arginase family
BI317_24570	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BI317_24980	COG1199	ATP-dependent helicase activity
BI317_24990	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BI317_25000	COG0745	RESPONSE REGULATOR receiver
BI317_25080	COG1525	nuclease
BI317_25135	COG1475	DNA binding
BI317_25170	COG0629	single-stranded DNA binding
BI317_25200	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BI317_25375	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BI317_25420	COG2963	transposase activity
BI317_25520	COG3328	transposase activity
BI317_25585	COG3039	Transposase
BI317_25605	COG5599	Phosphatase
BI317_25675	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BI317_25690	COG2801	Transposase and inactivated derivatives
BI317_25695	COG2963	transposase activity
BI317_25720	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BI317_25870	COG4962	Type ii secretion system protein e