locus-tag class description DYQ48_00005 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) DYQ48_00010 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) DYQ48_00015 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) DYQ48_00025 ENOG4108K0D peptidase, M48 DYQ48_00060 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) DYQ48_00070 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) DYQ48_00085 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation DYQ48_00100 ENOG4105C5I Dehydrogenase DYQ48_00105 ENOG4105CN1 protease DYQ48_00110 ENOG41063SB peptidase DYQ48_00120 ENOG4107VAM peptidase, m28 DYQ48_00150 ENOG4105DQ4 alcohol dehydrogenase DYQ48_00160 ENOG4105BZ8 glutamate synthase DYQ48_00165 ENOG4105CBC glutamate synthase DYQ48_00205 ENOG4105EXG Transcriptional regulator DYQ48_00215 ENOG4105E2V Glycosyltransferase 36 DYQ48_00240 ENOG4105CBZ Short-chain dehydrogenase reductase Sdr DYQ48_00245 ENOG4105KVH Transcriptional regulator DYQ48_00325 ENOG4108I5C dEAD DEAH box helicase DYQ48_00335 ENOG4108UT2 hemolysin iii DYQ48_00380 ENOG4105CC0 LysR family Transcriptional regulator DYQ48_00400 ENOG4105DYS nad(p)h dehydrogenase (quinone) DYQ48_00405 ENOG4108NSC Pfam:DUF88 DYQ48_00415 ENOG4105KVH Transcriptional regulator DYQ48_00490 ENOG4105D4Y metalloprotease DYQ48_00500 ENOG4105E09 nadh pyrophosphatase DYQ48_00515 ENOG4105K63 Thioredoxin DYQ48_00520 ENOG4105CSH Transporter DYQ48_00560 ENOG4105C7R Atpase associated with various cellular activities aaa_3 DYQ48_00605 ENOG4105CZI D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 DYQ48_00610 ENOG4105CGF Aromatic amino acid aminotransferase DYQ48_00615 ENOG4105CHB tonB-dependent Receptor DYQ48_00625 ENOG41082W1 Cupin 2, conserved barrel domain protein DYQ48_00635 ENOG4105C26 Dehydrogenase DYQ48_00660 ENOG4105DQE DNA ligase DYQ48_00675 ENOG4105DMF Dehydrogenase DYQ48_00695 ENOG4105BZU Histidine kinase DYQ48_00700 ENOG4105WH1 Two component transcriptional regulator luxr family DYQ48_00715 ENOG4108M3R transcriptional activator CadC DYQ48_00720 ENOG4105RKW reductase (By DYQ48_00730 ENOG4105D7K pfkb domain protein DYQ48_00735 ENOG4105D05 Receptor DYQ48_00780 ENOG4107RRE RNA-directed DNA polymerase DYQ48_00850 ENOG4105F2I Transposase DYQ48_00910 ENOG4105EP6 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity) DYQ48_00915 ENOG4105CG3 alpha amylase, catalytic region DYQ48_00920 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) DYQ48_00950 ENOG4107TDE lipolytic protein G-D-S-L family DYQ48_00955 ENOG4105EBR Carboxylesterase DYQ48_00970 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit DYQ48_00980 ENOG4105CG6 trap dicarboxylate transporter dctm subunit DYQ48_00985 ENOG4105DSG hydrolase family 43 DYQ48_00990 ENOG4105ETE Transcriptional regulator (LacI family DYQ48_01000 ENOG4105D50 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity) DYQ48_01005 ENOG4105CHR reductase DYQ48_01015 ENOG4107TDE lipolytic protein G-D-S-L family DYQ48_01035 ENOG4105MIR Phenylalanine 4-monooxygenase DYQ48_01040 ENOG4108YXU transcriptional regulator AsnC family DYQ48_01045 ENOG4105CNM Receptor DYQ48_01050 ENOG4105D78 K07001 NTE family protein DYQ48_01060 ENOG4105DKW ABC transporter DYQ48_01075 ENOG4108IJ8 ABC transporter DYQ48_01080 ENOG4105E90 ABC transporter DYQ48_01090 ENOG4105E46 N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process DYQ48_01100 ENOG4105CAF HipA N-terminal domain protein DYQ48_01140 ENOG4105D1F ATP-binding protein DYQ48_01145 ENOG4105M4E phosphohistidine phosphatase, SixA DYQ48_01155 ENOG4107RZC phospholipase d DYQ48_01160 ENOG4105KA0 thioesterase Superfamily protein DYQ48_01185 ENOG4108V1U phospholipid-binding protein DYQ48_01195 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) DYQ48_01200 ENOG4105C5F glutamine synthetase DYQ48_01210 ENOG4105BZU Histidine kinase DYQ48_01215 ENOG4105CUX Signal transduction histidine kinase DYQ48_01220 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family DYQ48_01225 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) DYQ48_01230 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) DYQ48_01240 ENOG4105CHU acetyl-coa acetyltransferase DYQ48_01285 ENOG4107YZP Rhodanese domain protein DYQ48_01290 ENOG4105IX2 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity) DYQ48_01295 ENOG4105CSF NADPH-dependent glycerol-3-phosphate dehydrogenase DYQ48_01305 ENOG4105C7K acetolactate synthase DYQ48_01310 ENOG4105BZU Histidine kinase DYQ48_01335 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) DYQ48_01350 ENOG4105E2T synthase III DYQ48_01355 ENOG4107R3N Filamentation induced by cAMP protein fic DYQ48_01360 ENOG4108J2P Alpha beta hydrolase fold DYQ48_01365 ENOG4105PI0 Ferredoxin DYQ48_01370 ENOG410680H amp-dependent synthetase and ligase DYQ48_01385 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase DYQ48_01400 ENOG4105CPF Cell wall formation (By similarity) DYQ48_01410 ENOG4105CNK Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity) DYQ48_01415 ENOG4105DR9 pseudouridine synthase DYQ48_01425 ENOG4108YZN class I peptide chain release factor DYQ48_01435 ENOG4105D44 asparaginase DYQ48_01440 ENOG4105DGW oligopeptidase A DYQ48_01460 ENOG4107R11 Transcriptional regulator DYQ48_01465 ENOG4107QP3 malate synthase g DYQ48_01475 ENOG4105BZU Histidine kinase DYQ48_01505 ENOG4107QX3 carboxylase DYQ48_01510 ENOG4105C1G acyl-Coa dehydrogenase DYQ48_01565 ENOG4105CKI cobalamin synthesis protein DYQ48_01580 ENOG4108TZV Membrane DYQ48_01590 ENOG4105D6Z AFG1 family ATPase DYQ48_01605 ENOG4105K56 Transcriptional regulator DYQ48_01610 ENOG4108ZHJ Organic hydroperoxide resistance protein DYQ48_01635 ENOG4105CV8 reductase DYQ48_01640 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein DYQ48_01655 ENOG4108R99 pseudouridine synthase DYQ48_01660 ENOG4108KPZ tonB-dependent Receptor DYQ48_01670 ENOG4105CQ7 ATP-dependent helicase DYQ48_01675 ENOG4105C8Q Methyl-accepting chemotaxis DYQ48_01685 ENOG4108W15 Protein of unknown function (DUF1456) DYQ48_01690 ENOG4105VT2 5-hydroxyisourate hydrolase DYQ48_01695 ENOG4105E1J oxidoreductase DYQ48_01715 ENOG4105C5R Aminotransferase DYQ48_01725 ENOG4105EQ2 LysR family Transcriptional regulator DYQ48_01730 ENOG4107RTG Major Facilitator superfamily DYQ48_01735 ENOG4105EXG Transcriptional regulator DYQ48_01740 ENOG4105CPT Alpha beta hydrolase DYQ48_01795 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) DYQ48_01815 ENOG4105C7N Xanthine uracil vitamin C permease DYQ48_01830 ENOG4105ETT transcriptional Regulator, LysR family DYQ48_01835 ENOG4105F8V Hydrolase, tatD family DYQ48_01850 ENOG4106NZI LysR family Transcriptional regulator DYQ48_01855 ENOG4105D94 Major Facilitator Superfamily DYQ48_01880 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) DYQ48_01885 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase DYQ48_01920 ENOG4105DAE Methylenetetrahydrofolate reductase DYQ48_01925 ENOG4105WPN DNA integration recombination invertion protein DYQ48_01930 ENOG4105DZ2 Transcriptional regulator DYQ48_01935 ENOG4108UZX fmn reductase DYQ48_01945 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) DYQ48_01960 ENOG4105ECR NmrA family DYQ48_02070 ENOG4105C01 Dihydroxy-acid dehydratase DYQ48_02075 ENOG4105KRS Proteinase inhibitor DYQ48_02080 ENOG4108Z0R Transferase DYQ48_02085 ENOG4105D2S major facilitator superfamily DYQ48_02090 ENOG4105CPI Metal Dependent Phosphohydrolase DYQ48_02125 ENOG41072AC 4-hydroxybenzoate 3-monooxygenase DYQ48_02140 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) DYQ48_02145 ENOG4105C6V Glycerol-3-phosphate dehydrogenase DYQ48_02150 ENOG4105E98 transcriptional regulator DeoR family DYQ48_02180 ENOG4105CHU acetyl-coa acetyltransferase DYQ48_02195 ENOG4107RAW 3-carboxy-cis-cis-muconate cycloisomerase DYQ48_02200 ENOG4105F2Z 3-oxoadipate enol-lactonase DYQ48_02205 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase DYQ48_02220 ENOG4107HP6 Transcriptional regulator DYQ48_02235 ENOG4105MH3 Protein of unknown function (DUF2490) DYQ48_02240 ENOG4107RE5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity) DYQ48_02250 ENOG4105C7B Threonine dehydratase DYQ48_02280 ENOG4107EXU Short-chain dehydrogenase reductase Sdr DYQ48_02290 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) DYQ48_02295 ENOG4105CZF Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) DYQ48_02300 ENOG41081UC Inherit from COG: Competence protein DYQ48_02310 ENOG4105C4G Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity) DYQ48_02340 ENOG4105C9K Endothelin-converting enzyme 1 DYQ48_02360 ENOG4105EGS Mechanosensitive ion channel DYQ48_02370 ENOG4107RES phosphoglycerol transferase I DYQ48_02385 ENOG4105CKW Inner membrane protein yedI DYQ48_02390 ENOG4105F32 YngK protein DYQ48_02395 ENOG4105BZU Histidine kinase DYQ48_02400 ENOG4105CXW Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity) DYQ48_02405 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) DYQ48_02410 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) DYQ48_02435 ENOG4105K4T epimerase DYQ48_02480 ENOG4105BZS acriflavin resistance protein DYQ48_02490 ENOG4105C1J atp-dependent rna helicase DYQ48_02500 ENOG4105C7S Dehydrogenase DYQ48_02510 ENOG4105CPP Dehydrogenase, E1 component DYQ48_02515 ENOG4107RUY (E1 component), alpha subunit DYQ48_02525 ENOG4105HJ8 Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity) DYQ48_02530 ENOG4105DUX Transporter DYQ48_02545 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase DYQ48_02550 ENOG4105WDY DNA (cytosine-5-)-methyltransferase DYQ48_02555 ENOG4105F1J Homogentisate 1,2-dioxygenase DYQ48_02570 ENOG4105KJM monovalent cation h antiporter subunit g DYQ48_02575 ENOG4105W4C monovalent cation H antiporter subunit F DYQ48_02585 ENOG4107R4Z monovalent cation h antiporter subunit d DYQ48_02590 ENOG4108ZE9 Monovalent cation H antiporter subunit C DYQ48_02595 ENOG4105D65 subunit l DYQ48_02655 ENOG4105CRQ synthase (Component I) DYQ48_02660 ENOG4107TE5 Lipid kinase DYQ48_02680 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) DYQ48_02685 ENOG4105C8V SAICAR synthetase DYQ48_02710 ENOG4105D74 hydrolase DYQ48_02765 ENOG4105VS8 Flagellar biosynthetic protein fliq DYQ48_02785 ENOG4108HR8 type iii secretion DYQ48_02805 ENOG4107Y59 type iii secretion DYQ48_02820 ENOG4108JIR Flagellum-specific ATP synthase DYQ48_02835 ENOG4105K44 type iii secretion DYQ48_02845 ENOG4105FTC Lytic transglycosylase catalytic DYQ48_02860 ENOG4105C8Q Methyl-accepting chemotaxis DYQ48_02865 ENOG4105DDQ anthranilate synthase DYQ48_02875 ENOG4108I0Q anthranilate phosphoribosyltransferase DYQ48_02890 ENOG4107RYR Transcriptional regulator, Crp Fnr family DYQ48_02895 ENOG4105FDS Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) DYQ48_02900 ENOG4105KPY Small multidrug resistance protein DYQ48_02910 ENOG4108UM5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity) DYQ48_02915 ENOG4108UJD 30S ribosomal protein S9 DYQ48_02940 ENOG4108UQY Iron-storage protein DYQ48_02945 ENOG4105BZU Histidine kinase DYQ48_02970 ENOG4108YX9 iron--sulfur cluster insertion protein erpA DYQ48_02980 ENOG4105E09 nadh pyrophosphatase DYQ48_02985 ENOG4105DH2 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity) DYQ48_03015 ENOG4105EM2 membrane DYQ48_03020 ENOG4105C12 Phosphoribosylglycinamide synthetase DYQ48_03025 ENOG4105DC1 bifunctional purine biosynthesis protein purh DYQ48_03035 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) DYQ48_03060 ENOG4105F59 Methylates ribosomal protein L11 (By similarity) DYQ48_03075 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase DYQ48_03085 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein DYQ48_03090 ENOG4108Z38 Catalyzes a trans-dehydration via an enolate intermediate (By similarity) DYQ48_03100 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) DYQ48_03105 ENOG4105VF7 tolerance protein DYQ48_03110 ENOG4108K8S endonuclease I DYQ48_03115 ENOG4105K5Y Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity) DYQ48_03150 ENOG4105EUP HipA domain protein DYQ48_03155 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) DYQ48_03180 ENOG4108S3W Anti-feci sigma factor, fecr DYQ48_03205 ENOG4105CE6 Adenylation and deadenylation of glutamate--ammonia ligase (By similarity) DYQ48_03210 ENOG4105EX9 Membrane DYQ48_03230 ENOG4108RDT NADH dehydrogenase NAD(P)H nitroreductase) DYQ48_03235 ENOG4108YYC ycei family DYQ48_03255 ENOG4105WSE Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity) DYQ48_03270 ENOG41065ZS Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme- A to the apo- acyl-carrier-protein of the malonate decarboxylase to yield holo- acyl-carrier-protein (By similarity) DYQ48_03275 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase DYQ48_03290 ENOG4105DRR Transcriptional regulator, GntR family DYQ48_03330 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) DYQ48_03390 ENOG4105C4R Atp-dependent dna helicase DYQ48_03515 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) DYQ48_03560 ENOG4105CHF Glutathione S-transferase DYQ48_03595 ENOG4105C5Z peptidase DYQ48_03600 ENOG4107QS8 (LipO)protein DYQ48_03605 ENOG4105BZU Histidine kinase DYQ48_03630 ENOG4105DFI Membrane DYQ48_03635 ENOG4105F87 Dehydratase DYQ48_03655 ENOG4105D7N magnesium and cobalt transport protein CorA DYQ48_03670 ENOG4107PMW Arabinan endo-1,5-alpha-L-arabinosidase DYQ48_03725 ENOG4105BZU Histidine kinase DYQ48_03735 ENOG4105C8Q Methyl-accepting chemotaxis DYQ48_03740 ENOG4106R7G Glycoside hydrolase family 5 DYQ48_03745 ENOG4105CHH sulfate transporter DYQ48_03750 ENOG4105BZU Histidine kinase DYQ48_03770 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) DYQ48_03780 ENOG4108HRK Histidine kinase DYQ48_03785 ENOG4108NEV two component transcriptional regulator, LytTR family DYQ48_03790 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) DYQ48_03845 ENOG4105WD1 Membrane DYQ48_03855 ENOG4105E4Z Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity) DYQ48_03865 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) DYQ48_03870 ENOG4108R5P Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity) DYQ48_03875 ENOG4105C4N this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity) DYQ48_03880 ENOG4105KNM Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) DYQ48_03910 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) DYQ48_03915 ENOG4105BZU Histidine kinase DYQ48_03920 ENOG4105CD8 aminopeptidase N DYQ48_03940 ENOG4105DZG Dehydrogenase DYQ48_03945 ENOG4108Q1J Extracellular solute-binding protein, family 3 DYQ48_03975 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family DYQ48_03985 ENOG4105DFF Rod shape-determining protein mreb DYQ48_03990 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) DYQ48_03995 ENOG4105VQ7 Rod shape-determining protein MreD DYQ48_04005 ENOG4105CNI cell division protein FtsW DYQ48_04015 ENOG4107WN4 Polygalacturonase DYQ48_04020 ENOG4105CVE Lytic murein transglycosylase DYQ48_04025 ENOG4105K6T rare lipoprotein A DYQ48_04030 ENOG4105DZ1 carboxypeptidase DYQ48_04045 ENOG4108BDP Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) DYQ48_04050 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) DYQ48_04055 ENOG4105CN1 protease DYQ48_04100 ENOG4108J5G 6-phosphogluconate dehydrogenase DYQ48_04105 ENOG4105D9R oxidoreductase DYQ48_04110 ENOG4105W4M Transport-associated protein DYQ48_04115 ENOG4105BZU Histidine kinase DYQ48_04125 ENOG4105BZU Histidine kinase DYQ48_04135 ENOG410642E Short chain dehydrogenase DYQ48_04175 ENOG4105GVR general secretion pathway protein D DYQ48_04180 ENOG4107QHF type ii secretion system protein e DYQ48_04185 ENOG4105D7Q type ii secretion system DYQ48_04190 ENOG4108VAU general secretion pathway protein G DYQ48_04195 ENOG4105VWV general secretion pathway protein h DYQ48_04200 ENOG4105X5Z General secretion pathway protein I DYQ48_04210 ENOG4105R04 type II secretion system protein K DYQ48_04235 ENOG4105CNT hydrolase family 2 DYQ48_04250 ENOG4105FDP GntR family transcriptional regulator DYQ48_04260 ENOG4105ETE Transcriptional regulator (LacI family DYQ48_04265 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) DYQ48_04270 ENOG4105CE4 GlcNAc 6-P deacetylase DYQ48_04305 ENOG4105CZ6 Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity) DYQ48_04310 ENOG4105C26 Dehydrogenase DYQ48_04315 ENOG4105C94 Transporter DYQ48_04325 ENOG4108Z33 Thiol disulfide Interchange Protein DYQ48_04335 ENOG4106RE7 Cytochrome DYQ48_04340 ENOG4105WHM Necessary for normal cell division and for the maintenance of normal septation (By similarity) DYQ48_04350 ENOG4105JJR Histidine kinase DYQ48_04355 ENOG4105DPZ Two component transcriptional regulator (Winged helix family DYQ48_04370 ENOG410903D sensor protein DYQ48_04385 ENOG4108QBQ Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione (By similarity) DYQ48_04395 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family DYQ48_04400 ENOG4105JAB phenazine biosynthesis protein, phzf family DYQ48_04445 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) DYQ48_04450 ENOG4105CD3 dihydroorotase DYQ48_04475 ENOG4105CNM Receptor DYQ48_04510 ENOG4108JJA ABC, transporter DYQ48_04530 ENOG4105F2I Transposase DYQ48_04540 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) DYQ48_04565 ENOG4107QW3 Sucrose phosphorylase DYQ48_04580 ENOG4105ETE Transcriptional regulator (LacI family DYQ48_04585 ENOG4105CHR reductase DYQ48_04590 ENOG4105D4T Citrate transporter DYQ48_04605 ENOG4105DHQ Histidine kinase DYQ48_04610 ENOG4106JDA Phosphoglycerate transport regulatory protein PGTC DYQ48_04615 ENOG4105WH1 Two component transcriptional regulator luxr family DYQ48_04640 ENOG4105CK2 sodium dicarboxylate symporter DYQ48_04645 ENOG4105C6K Malic enzyme DYQ48_04670 ENOG4105D1S lipid A biosynthesis DYQ48_04675 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase DYQ48_04685 ENOG4105DFG type I secretion outer membrane protein DYQ48_04690 ENOG4105E26 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity) DYQ48_04700 ENOG4105BZU Histidine kinase DYQ48_04705 ENOG4108MP6 LysR family Transcriptional regulator DYQ48_04710 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) DYQ48_04715 ENOG4105MQS Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) DYQ48_04720 ENOG4105F2W methyltransferase DYQ48_04725 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) DYQ48_04735 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) DYQ48_04740 ENOG4105C7B Threonine dehydratase DYQ48_04760 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) DYQ48_04770 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein DYQ48_04785 ENOG4108M3R transcriptional activator CadC DYQ48_04790 ENOG4105ECQ AraC Family Transcriptional Regulator DYQ48_04805 ENOG4105F0N pyrophosphate phospho-hydrolase DYQ48_04815 ENOG4105EAY pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for DYQ48_04835 ENOG4105CC8 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity) DYQ48_04840 ENOG4105DFU Cell wall formation (By similarity) DYQ48_04850 ENOG4105FFC UPF0187 protein DYQ48_04860 ENOG410841Q phosphoesterase PA-phosphatase related protein DYQ48_04870 ENOG41061TZ Short-chain dehydrogenase reductase Sdr DYQ48_04885 ENOG4105EYW Ion transport protein DYQ48_04890 ENOG4105C8Y Acetylornithine aminotransferase DYQ48_04920 ENOG4105CIH Imidazole acetol-phosphate transaminase DYQ48_04925 ENOG41090JD Blue (Type 1) copper domain protein DYQ48_04930 ENOG41061ZR Transcriptional regulator DYQ48_04935 ENOG4105CDM Glutamate-1-semialdehyde aminotransferase DYQ48_04950 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) DYQ48_04955 ENOG4105VCQ rubredoxin DYQ48_04960 ENOG41063JG Transcriptional regulator DYQ48_04980 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase DYQ48_04990 ENOG4105W8B Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity) DYQ48_05005 ENOG4107RAQ aminopeptidase DYQ48_05010 ENOG4105D9Y Splits dipeptides with a prolyl residue in the C- terminal position (By similarity) DYQ48_05025 ENOG4105CSA Coproporphyrinogen iii oxidase DYQ48_05030 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) DYQ48_05035 ENOG4108ZI4 Glyoxalase Bleomycin resistance protein (Dioxygenase DYQ48_05040 ENOG4105ED0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity) DYQ48_05045 ENOG4105DSJ YicC domain protein DYQ48_05050 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) DYQ48_05055 ENOG4105VFG Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity) DYQ48_05060 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) DYQ48_05065 ENOG4105KME endoribonuclease L-psp DYQ48_05070 ENOG4105CB5 ATP-dependent DNA helicase recG DYQ48_05075 ENOG4105DU0 nucleoside hydrolase DYQ48_05085 ENOG4105BZN citrate synthase DYQ48_05095 ENOG4108JQC penicillin-binding protein 1A DYQ48_05120 ENOG4105E4G Type IV pilus DYQ48_05125 ENOG4105C7R Atpase associated with various cellular activities aaa_3 DYQ48_05160 ENOG4105CK2 sodium dicarboxylate symporter DYQ48_05165 ENOG4105CV1 Transketolase (EC 2.2.1.1) DYQ48_05175 ENOG4105CNM Receptor DYQ48_05180 ENOG4105CBN LysR family transcriptional regulator DYQ48_05185 ENOG4105CHR reductase DYQ48_05200 ENOG4107Y2H ErfK ybiS ycfS ynhG family protein DYQ48_05235 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) DYQ48_05240 ENOG4105E0C molybdate abc transporter DYQ48_05245 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein DYQ48_05250 ENOG4107S76 domain protein DYQ48_05260 ENOG4105EIF outer membrane protein W DYQ48_05275 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase DYQ48_05300 ENOG4105BZA Phosphoglycerate kinase DYQ48_05310 ENOG4105CA9 Pyruvate kinase DYQ48_05320 ENOG4107R1Y fructose-bisphosphate aldolase DYQ48_05325 ENOG4108UVJ appr-1-p processing domain protein DYQ48_05345 ENOG4107R11 Transcriptional regulator DYQ48_05365 ENOG4105BZU Histidine kinase DYQ48_05390 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) DYQ48_05395 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) DYQ48_05400 ENOG4105C11 sulfate adenylyltransferase), subunit 2 DYQ48_05405 ENOG4105C3T may be the GTPase, regulating ATP sulfurylase activity (By similarity) DYQ48_05410 ENOG4105C1P efflux transporter, rnd family, mfp subunit DYQ48_05415 ENOG4105BZS acriflavin resistance protein DYQ48_05435 ENOG4105C2N RNA methyltransferase TrmH family group 3 DYQ48_05440 ENOG4105EBR Carboxylesterase DYQ48_05465 ENOG4105ETE Transcriptional regulator (LacI family DYQ48_05475 ENOG4105M2E Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity) DYQ48_05500 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) DYQ48_05510 ENOG4105CA8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity) DYQ48_05560 ENOG4105W5Q DNA repair protein (RadC DYQ48_05730 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) DYQ48_05775 ENOG4105W39 Membrane DYQ48_05780 ENOG4105C8Q Methyl-accepting chemotaxis DYQ48_05815 ENOG4105D9I Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity) DYQ48_05820 ENOG4105ETX regulatoR DYQ48_05825 ENOG4105BZU Histidine kinase DYQ48_05850 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) DYQ48_05855 ENOG4105EHH Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity) DYQ48_05860 ENOG4105D7Q type ii secretion system DYQ48_05870 ENOG4105KHS type IV fimbrial pilin protein DYQ48_05875 ENOG4107QHF type ii secretion system protein e DYQ48_05880 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family DYQ48_05885 ENOG4107TUY Histidine kinase DYQ48_05890 ENOG4105CMV Succinyl-CoA synthetase subunit beta DYQ48_05895 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha DYQ48_05900 ENOG4105JQN Transcriptional regulator DYQ48_05925 ENOG4105C4K Nad synthetase DYQ48_05935 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane DYQ48_05940 ENOG4105C34 Pseudouridine synthase DYQ48_05955 ENOG4105KIR Thiol-disulfide oxidoreductase dcc DYQ48_05960 ENOG4105C8Q Methyl-accepting chemotaxis DYQ48_05965 ENOG4105DZG Dehydrogenase DYQ48_05970 ENOG4105C1K alpha-alpha-trehalose-phosphate synthase DYQ48_05975 ENOG4105BZP glycoside hydrolase 15-related DYQ48_05980 ENOG4108K4C ec 3.1.3.12 DYQ48_05985 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) DYQ48_06035 ENOG41082IR Excinuclease ABC C subunit domain protein DYQ48_06040 ENOG4107ZSV Receptor DYQ48_06050 ENOG4105CPC Aldo Keto reductase DYQ48_06055 ENOG4105GVF (ABC) transporter DYQ48_06060 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component DYQ48_06065 ENOG4105E2Y ABC, transporter DYQ48_06070 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit DYQ48_06080 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) DYQ48_06090 ENOG4108YZT Adenosylcobinamide kinase DYQ48_06095 ENOG4105CUP Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity) DYQ48_06110 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) DYQ48_06115 ENOG4105DBM Siderophore biosynthesis protein DYQ48_06135 ENOG4105GAV receptor DYQ48_06145 ENOG4105CKD glutathione-regulated potassium-efflux system protein DYQ48_06155 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) DYQ48_06160 ENOG4107RNH Outer membrane receptor FepA DYQ48_06165 ENOG4107RNH Outer membrane receptor FepA DYQ48_06170 ENOG4105C5H ABC transporter DYQ48_06180 ENOG4105ETT transcriptional Regulator, LysR family DYQ48_06195 ENOG4105HSS phospholipase C DYQ48_06210 ENOG4108ISG Major Facilitator DYQ48_06230 ENOG4105C9M aspartyl-trna synthetase DYQ48_06250 ENOG4105CDY transcriptional regulatory protein DYQ48_06255 ENOG4105NHU Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity) DYQ48_06260 ENOG4105KA4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity) DYQ48_06270 ENOG4105DFH Transport of potassium into the cell (By similarity) DYQ48_06280 ENOG4107YD3 Thioesterase DYQ48_06285 ENOG4105E02 MotA TolQ exbB proton channel DYQ48_06290 ENOG4105M8F Biopolymer transport protein exbD tolR DYQ48_06300 ENOG4107R6Y Involved in the TonB-independent uptake of proteins (By similarity) DYQ48_06305 ENOG4105KCK Peptidoglycan-associated lipoprotein DYQ48_06315 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) DYQ48_06320 ENOG4107S5I aldo keto reductase DYQ48_06380 ENOG4108P8R DYQ48_06410 ENOG410903D sensor protein DYQ48_06465 ENOG4105C9U ATP-dependent DNA helicase RecQ DYQ48_06475 ENOG4105CQ7 ATP-dependent helicase DYQ48_06485 ENOG4105CHC glucokinase (EC 2.7.1.2) DYQ48_06505 ENOG41086XE Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity) DYQ48_06510 ENOG4105JIE May be involved in the transport of PQQ or its precursor to the periplasm (By similarity) DYQ48_06515 ENOG410698T Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide (By similarity) DYQ48_06520 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) DYQ48_06535 ENOG4105BZ4 penicillin-binding protein DYQ48_06545 ENOG4105DVT helicase DYQ48_06550 ENOG41072GX Peptidase M22 Glycoprotease DYQ48_06560 ENOG4105D7Z glutathione synthase DYQ48_06565 ENOG4108UNF response regulator DYQ48_06570 ENOG4105M3Z response regulator DYQ48_06575 ENOG410807Z Modulation of CheA activity in response to attractants (Chemotaxis DYQ48_06580 ENOG4105C8Q Methyl-accepting chemotaxis DYQ48_06585 ENOG4105CBS Chea signal transduction histidine kinase DYQ48_06590 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) DYQ48_06600 ENOG4105D9U N-acetyltransferase DYQ48_06620 ENOG4105JVQ RNA Polymerase DYQ48_06625 ENOG4105CP2 von willebrand factor, type a DYQ48_06640 ENOG4106N3A copper homeostasis protein cutc DYQ48_06690 ENOG4105CWX Alpha-1,2-mannosidase DYQ48_06700 ENOG4105F8D glycoside hydrolase family 4 DYQ48_06710 ENOG4107QTZ amino acid DYQ48_06760 ENOG4105VRS hydrolase family 18 DYQ48_06775 ENOG4105CHC glucokinase (EC 2.7.1.2) DYQ48_06780 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) DYQ48_06790 ENOG4107RK2 ADP-ribose diphosphatase NudE DYQ48_06795 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase DYQ48_06800 ENOG4105DXN mazG family DYQ48_06805 ENOG4105KK4 UPF0060 membrane protein DYQ48_06810 ENOG4105D43 The glycine cleavage system catalyzes the degradation of glycine (By similarity) DYQ48_06815 ENOG4105KE9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity) DYQ48_06840 ENOG4105F2I Transposase DYQ48_06850 ENOG4107QPN acyl-Coa dehydrogenase DYQ48_06860 ENOG4108IG5 Transcriptional regulator DYQ48_06875 ENOG4105E0F Histidine kinase DYQ48_06910 ENOG4105F2I Transposase DYQ48_06940 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) DYQ48_06950 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) DYQ48_06955 ENOG4108VKV Monofunctional biosynthetic peptidoglycan transglycosylase DYQ48_06965 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) DYQ48_06970 ENOG41066T0 asmA family DYQ48_06975 ENOG4108UT2 hemolysin iii DYQ48_06980 ENOG4105C8A Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity) DYQ48_06990 ENOG4106TYC homoserine o-acetyltransferase (EC 2.3.1.31) DYQ48_06995 ENOG4105C28 cystathionine DYQ48_07000 ENOG4105CFH Aspartokinase DYQ48_07010 ENOG4105EJQ L-serine dehydratase DYQ48_07025 ENOG4105VEQ Cold shock protein DYQ48_07035 ENOG4105CPW cytochrome b561 DYQ48_07040 ENOG4108YYC ycei family DYQ48_07045 ENOG4105BZU Histidine kinase DYQ48_07050 ENOG4105BZU Histidine kinase DYQ48_07055 ENOG4105BZU Histidine kinase DYQ48_07060 ENOG4105BZU Histidine kinase DYQ48_07065 ENOG4105C0R drug resistance transporter emrb qaca subfamily DYQ48_07075 ENOG4105CGP Urocanate hydratase DYQ48_07085 ENOG4105C84 Histidine ammonia-lyase DYQ48_07090 ENOG4105CI2 imidazolone-5-propionate hydrolase DYQ48_07125 ENOG4105DQ2 Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity) DYQ48_07130 ENOG4105CCD The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity) DYQ48_07135 ENOG4107QM1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity) DYQ48_07140 ENOG4105CQC Prephenate dehydratase DYQ48_07145 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase DYQ48_07160 ENOG4105CGR Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity) DYQ48_07165 ENOG4105CC0 LysR family Transcriptional regulator DYQ48_07220 ENOG4105C8Q Methyl-accepting chemotaxis DYQ48_07240 ENOG4105BZU Histidine kinase DYQ48_07250 ENOG4105CQZ Histidine kinase DYQ48_07265 ENOG4105F2I Transposase DYQ48_07270 ENOG4105VCD cytoplasmic protein DYQ48_07275 ENOG4105D22 carbon starvation protein DYQ48_07280 ENOG4105EUB pirin domain protein DYQ48_07295 ENOG4105EUB pirin domain protein DYQ48_07300 ENOG4105Y7X Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity) DYQ48_07315 ENOG4105C9K Endothelin-converting enzyme 1 DYQ48_07320 ENOG4107RZC phospholipase d DYQ48_07330 ENOG4105BZU Histidine kinase DYQ48_07335 ENOG4105BZU Histidine kinase DYQ48_07340 ENOG4108V3W Chemotaxis protein, CheW DYQ48_07350 ENOG4105CBS Chea signal transduction histidine kinase DYQ48_07360 ENOG4108JA2 transcriptioN-repair coupling factor DYQ48_07375 ENOG4105D6S protein involved in catabolism of external DNA DYQ48_07380 ENOG4105E3W Two component transcriptional regulator (Winged helix family DYQ48_07385 ENOG4105EB3 Histidine kinase DYQ48_07395 ENOG4105CT7 inner membrane cred family protein DYQ48_07420 ENOG4105C20 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity) DYQ48_07425 ENOG4105MYN Zinc uptake regulation protein DYQ48_07440 ENOG4105C1P efflux transporter, rnd family, mfp subunit DYQ48_07445 ENOG4105BZS acriflavin resistance protein DYQ48_07450 ENOG4105ENJ RND efflux system, outer membrane lipoprotein DYQ48_07455 ENOG4108JGH Tetr family transcriptional regulator DYQ48_07460 ENOG4107SET aldo keto reductase DYQ48_07465 ENOG4105EQ2 LysR family Transcriptional regulator DYQ48_07485 ENOG4105CC0 LysR family Transcriptional regulator DYQ48_07490 ENOG4105F27 Major Facilitator DYQ48_07495 ENOG4105CPC Aldo Keto reductase DYQ48_07500 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin DYQ48_07510 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin DYQ48_07530 ENOG4105UGU tonB-dependent Receptor DYQ48_07585 ENOG4105D0A hydroxylase DYQ48_07605 ENOG4105EMN RNA polymerase sigma factor DYQ48_07615 ENOG4105BZU Histidine kinase DYQ48_07620 ENOG4105FE9 pseudouridine synthase DYQ48_07625 ENOG4105BZU Histidine kinase DYQ48_07640 ENOG4108YYX Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity) DYQ48_07645 ENOG4105FQP Beta-lactamase DYQ48_07660 ENOG4105BZ1 (ABC) transporter DYQ48_07705 ENOG4105WG9 Conserved Protein DYQ48_07715 ENOG4105CR8 Transcriptional regulator DYQ48_07730 ENOG4105C1P efflux transporter, rnd family, mfp subunit DYQ48_07750 ENOG4105BZU Histidine kinase DYQ48_07760 ENOG4105BZU Histidine kinase DYQ48_07815 ENOG4108UH4 Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity) DYQ48_07830 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) DYQ48_07835 ENOG41090R7 Ferric uptake DYQ48_07840 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) DYQ48_07845 ENOG4105CI8 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity) DYQ48_07850 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ DYQ48_07855 ENOG4105CFG Acts as a chaperone (By similarity) DYQ48_07890 ENOG4108JJA ABC, transporter DYQ48_07895 ENOG4105C5Q Transcriptional regulator DYQ48_07900 ENOG4105BZ1 (ABC) transporter DYQ48_07910 ENOG4108URH decarboxylase DYQ48_07920 ENOG4105C7S Dehydrogenase DYQ48_07925 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 DYQ48_07935 ENOG4105EZE Cupin 4 family protein DYQ48_07950 ENOG4107QTF adenylosuccinate lyase DYQ48_07955 ENOG4105C37 (CBS) domain DYQ48_07985 ENOG4105CZV ABC transporter DYQ48_07990 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family DYQ48_08005 ENOG4108V1T peptidylprolyl cis-trans isomerase DYQ48_08010 ENOG4105C6Y Udp-glucose 6-dehydrogenase DYQ48_08030 ENOG4105ETE Transcriptional regulator (LacI family DYQ48_08040 ENOG4105D7K pfkb domain protein DYQ48_08050 ENOG4105C3R Methionine synthase DYQ48_08055 ENOG4105C3R Methionine synthase DYQ48_08065 ENOG4105C1G acyl-Coa dehydrogenase DYQ48_08080 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) DYQ48_08090 ENOG4105C2N RNA methyltransferase TrmH family group 3 DYQ48_08095 ENOG4105BZU Histidine kinase DYQ48_08100 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) DYQ48_08110 ENOG4108UTW Plays a role in the regulation of phosphate uptake DYQ48_08115 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) DYQ48_08120 ENOG4105E2Z phosphate ABC transporter (Permease DYQ48_08125 ENOG4105C8U phosphate abc transporter DYQ48_08130 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) DYQ48_08150 ENOG4107B2H carbonic anhydrase DYQ48_08155 ENOG4105CHH sulfate transporter DYQ48_08165 ENOG4105CSM endonuclease III DYQ48_08175 ENOG4105E39 Enoyl-CoA hydratase DYQ48_08180 ENOG4108V1T peptidylprolyl cis-trans isomerase DYQ48_08185 ENOG4105P8F nudix hydrolase DYQ48_08190 ENOG4105KHC sulfurtransferase DYQ48_08220 ENOG4105C5H ABC transporter DYQ48_08230 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) DYQ48_08235 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) DYQ48_08245 ENOG4105IH7 synthase DYQ48_08260 ENOG4105CJB Exodeoxyribonuclease I DYQ48_08265 ENOG4107RQD Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity) DYQ48_08280 ENOG4105C3W Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity) DYQ48_08285 ENOG41077A9 carbonic anhydrase DYQ48_08305 ENOG4105C5S asparaginyl-tRNA synthetase DYQ48_08310 ENOG4108YX9 iron--sulfur cluster insertion protein erpA DYQ48_08315 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) DYQ48_08320 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) DYQ48_08325 ENOG4105K9Q Binds to the 23S rRNA (By similarity) DYQ48_08335 ENOG4107NPY receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity) DYQ48_08340 ENOG4105CIH Imidazole acetol-phosphate transaminase DYQ48_08345 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) DYQ48_08350 ENOG4105CAP With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity) DYQ48_08360 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) DYQ48_08365 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) DYQ48_08395 ENOG4108S0S Nucleotidyl transferase DYQ48_08400 ENOG4105EHM Aminoglycoside phosphotransferase DYQ48_08410 ENOG4105C9Y Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity) DYQ48_08415 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein DYQ48_08425 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) DYQ48_08430 ENOG4105CJ2 (LipO)protein DYQ48_08455 ENOG4107E2E PKHD-type hydroxylase DYQ48_08460 ENOG4108ESX Receptor DYQ48_08475 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) DYQ48_08480 ENOG4105C9B Cysteine desulfurase DYQ48_08485 ENOG4105JRK feS assembly protein SufD DYQ48_08490 ENOG4105C3K feS assembly ATPase SufC DYQ48_08525 ENOG4108K5P (LipO)protein DYQ48_08535 ENOG4105II7 pyrroline-5-carboxylate reductase DYQ48_08540 ENOG4105DFA alanine racemase domain protein DYQ48_08550 ENOG4105CZX twitching motility protein DYQ48_08555 ENOG4105CZX twitching motility protein DYQ48_08565 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) DYQ48_08575 ENOG4108UJU UPF0301 protein DYQ48_08580 ENOG4107Y66 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) DYQ48_08585 ENOG4105CXT aspartate transcarbamylase DYQ48_08590 ENOG4108Z9K Osmotically inducible protein DYQ48_08600 ENOG4105JAB phenazine biosynthesis protein, phzf family DYQ48_08610 ENOG4105CFH Aspartokinase DYQ48_08630 ENOG4105EAH synthase DYQ48_08635 ENOG4108UUM single-stranded DNA-binding protein DYQ48_08655 ENOG4107XKX isoquinoline 1-oxidoreductase, alpha subunit DYQ48_08660 ENOG4105DIP Molybdopterin dehydrogenase FAD-binding DYQ48_08665 ENOG4105C7W Xanthine dehydrogenase DYQ48_08670 ENOG4107XAN XdhC and CoxI family DYQ48_08700 ENOG4107YBY Hydrolase DYQ48_08730 ENOG4105KWW Biogenesis protein DYQ48_08735 ENOG4107QX9 Thiol disulfide interChange protein DYQ48_08740 ENOG4105DA4 cytochrome c-type biogenesis protein DYQ48_08745 ENOG4108ZKK Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity) DYQ48_08755 ENOG41060IM Heme exporter protein DYQ48_08770 ENOG4105EMN RNA polymerase sigma factor DYQ48_08805 ENOG4105EGZ biosynthesis protein DYQ48_08835 ENOG4105F59 Methylates ribosomal protein L11 (By similarity) DYQ48_08840 ENOG4107QPH glycogen) synthase DYQ48_08845 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) DYQ48_08860 ENOG4105EHU Circadian clock protein KaiC DYQ48_08865 ENOG4105BZ1 (ABC) transporter DYQ48_08870 ENOG41079KZ Major Facilitator Superfamily DYQ48_08880 ENOG4105DEN Luciferase family DYQ48_08925 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) DYQ48_08935 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) DYQ48_08940 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase DYQ48_08950 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) DYQ48_08955 ENOG4105XX3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) DYQ48_08975 ENOG4108DG9 Smr protein MutS2 DYQ48_08980 ENOG4105CV2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity) DYQ48_08985 ENOG4105E26 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity) DYQ48_08990 ENOG4108UM1 dedA family DYQ48_08995 ENOG4108K5P (LipO)protein DYQ48_09005 ENOG4105HBR Rna-binding protein DYQ48_09010 ENOG4105F7M Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity) DYQ48_09015 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) DYQ48_09020 ENOG4105EEI dihydropteroate synthase DYQ48_09025 ENOG4105DKX Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity) DYQ48_09030 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) DYQ48_09035 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) DYQ48_09040 ENOG4107TH8 cina domain protein DYQ48_09050 ENOG4105CNK Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity) DYQ48_09065 ENOG4105Y3E Modulates RecA activity (By similarity) DYQ48_09070 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) DYQ48_09075 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) DYQ48_09085 ENOG4107SDU Methyl-accepting chemotaxis DYQ48_09115 ENOG4105DWF phosphomethylpyrimidine kinase DYQ48_09130 ENOG4108IAB Phoh family DYQ48_09135 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen DYQ48_09150 ENOG4107TUS Dihydrodipicolinate synthase DYQ48_09160 ENOG4108Z4U Ferredoxin DYQ48_09180 ENOG4108RTU Aldolase DYQ48_09225 ENOG4105CMG Carbohydrate kinase DYQ48_09230 ENOG4105C93 Xylose Isomerase DYQ48_09255 ENOG4108KNB n-acetylmuramoyl-l-alanine amidase DYQ48_09270 ENOG4105DJ0 Poly(A) Polymerase DYQ48_09275 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase DYQ48_09280 ENOG4105CCG Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity) DYQ48_09285 ENOG4108IAA Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity) DYQ48_09290 ENOG4108Z2X Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity) DYQ48_09295 ENOG4107QP8 phosphohexose isomerase DYQ48_09345 ENOG4105KU2 hydrolase family 5 DYQ48_09355 ENOG4108UYB regulatoR DYQ48_09365 ENOG4105C4E Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity) DYQ48_09370 ENOG410841Q phosphoesterase PA-phosphatase related protein DYQ48_09385 ENOG4108SXK Transporter Drug Metabolite Exporter family DYQ48_09390 ENOG4105D4A Cell wall formation (By similarity) DYQ48_09395 ENOG4107QYT Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity) DYQ48_09410 ENOG4105C26 Dehydrogenase DYQ48_09455 ENOG4105CND Glycosyl transferase, family 2 DYQ48_09460 ENOG4107BJW polysaccharide deacetylase DYQ48_09490 ENOG4105KAV tspo and mbr like protein DYQ48_09495 ENOG4105CFH Aspartokinase DYQ48_09520 ENOG4105DS0 Transcriptional regulator, Crp Fnr family DYQ48_09545 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) DYQ48_09550 ENOG4105CIH Imidazole acetol-phosphate transaminase DYQ48_09555 ENOG4105ECC imidazole-glycerol-phosphate dehydratase DYQ48_09560 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) DYQ48_09565 ENOG4105CJV Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase DYQ48_09570 ENOG4105C0S IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) DYQ48_09575 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase DYQ48_09595 ENOG4106YVY Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity) DYQ48_09600 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) DYQ48_09605 ENOG4107QY0 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) DYQ48_09615 ENOG4105CUB amino acid DYQ48_09620 ENOG4105CUB amino acid DYQ48_09635 ENOG4108JQ1 Dehydrogenase DYQ48_09640 ENOG4105CQB FAD linked oxidase domain protein DYQ48_09660 ENOG4105FUQ Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) DYQ48_09670 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase DYQ48_09675 ENOG4105E39 Enoyl-CoA hydratase DYQ48_09685 ENOG4105CE1 Ferrous iron transport protein b DYQ48_09695 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family DYQ48_09700 ENOG4108RPX mosc domain containing protein DYQ48_09705 ENOG4105DUK Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity) DYQ48_09710 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain DYQ48_09720 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain DYQ48_09725 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) DYQ48_09735 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) DYQ48_09760 ENOG4105CRK lysyL-tRNA synthetase DYQ48_09765 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase DYQ48_09770 ENOG4105BZU Histidine kinase DYQ48_09775 ENOG4105BZU Histidine kinase DYQ48_09785 ENOG4105CEY Amp-dependent synthetase and ligase DYQ48_09795 ENOG4107QM5 aconitate hydratase DYQ48_09810 ENOG4107QIJ Aconitate hydratase 2 DYQ48_09815 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) DYQ48_09830 ENOG4105BZU Histidine kinase DYQ48_09835 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) DYQ48_09840 ENOG4108Z4W Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity) DYQ48_09845 ENOG4105BZU Histidine kinase DYQ48_09850 ENOG4105C8Q Methyl-accepting chemotaxis DYQ48_09860 ENOG4108V3W Chemotaxis protein, CheW DYQ48_09875 ENOG4105C8Q Methyl-accepting chemotaxis DYQ48_09880 ENOG4105C8Q Methyl-accepting chemotaxis DYQ48_09885 ENOG4105C8Q Methyl-accepting chemotaxis DYQ48_09890 ENOG4105C8Q Methyl-accepting chemotaxis DYQ48_09895 ENOG4105C8Q Methyl-accepting chemotaxis DYQ48_09905 ENOG4105C8Q Methyl-accepting chemotaxis DYQ48_09910 ENOG4105C8Q Methyl-accepting chemotaxis DYQ48_09930 ENOG4105C8Q Methyl-accepting chemotaxis DYQ48_09940 ENOG4105CBS Chea signal transduction histidine kinase DYQ48_09945 ENOG4108VYJ response regulator receiver protein DYQ48_09955 ENOG4108V3W Chemotaxis protein, CheW DYQ48_09960 ENOG4107QJE Chromosome Partitioning Protein DYQ48_09965 ENOG4106VK6 Flagellar motor protein DYQ48_09970 ENOG4105E14 MotA TolQ exbB proton channel DYQ48_09980 ENOG4105VDM plasmid maintenance system antidote protein, xre family DYQ48_09985 ENOG4105CBS Chea signal transduction histidine kinase DYQ48_09995 ENOG4108VYJ response regulator receiver protein DYQ48_10000 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) DYQ48_10005 ENOG4107R21 site-determining protein DYQ48_10010 ENOG4105FZW flagellar biosynthesis regulator FlhF DYQ48_10020 ENOG4105D7B Flagellar biosynthesis protein flha DYQ48_10025 ENOG4105D00 flagellar biosynthetic protein flhB DYQ48_10030 ENOG4105BZU Histidine kinase DYQ48_10035 ENOG4105BZU Histidine kinase DYQ48_10040 ENOG4105BZU Histidine kinase DYQ48_10045 ENOG4105D19 Role in flagellar biosynthesis (By similarity) DYQ48_10050 ENOG4105VS8 Flagellar biosynthetic protein fliq DYQ48_10055 ENOG4105CN7 Flagellar biosynthetic protein FliP DYQ48_10060 ENOG4105K0P flagellar biosynthesis protein DYQ48_10065 ENOG4105DD5 Flagellar motor switch protein DYQ48_10070 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) DYQ48_10090 ENOG4108JIR Flagellum-specific ATP synthase DYQ48_10100 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) DYQ48_10105 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) DYQ48_10110 ENOG4105VQ0 flagellar hook-basal body complex protein fliE DYQ48_10115 ENOG4105F2I Transposase DYQ48_10135 ENOG4107RGC Glycosyl transferase, family 2 DYQ48_10140 ENOG4105C74 pyruvyl transferase DYQ48_10165 ENOG4105CHR reductase DYQ48_10170 ENOG4105H9W Short-chain dehydrogenase reductase Sdr DYQ48_10175 ENOG4108P1X synthase DYQ48_10195 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) DYQ48_10200 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) DYQ48_10220 ENOG4105MQ3 flagellar protein FliS DYQ48_10225 ENOG4107W9T flagellar hook-associated DYQ48_10245 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj DYQ48_10255 ENOG4107W7W Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity) DYQ48_10260 ENOG4105CGA flagellar basal-body rod protein FlgG DYQ48_10265 ENOG4108KPB Flagellar basal-body rod protein FlgF DYQ48_10270 ENOG4105BZE flagellar hook protein, FlgE DYQ48_10275 ENOG410822I Flagellar hook capping protein DYQ48_10280 ENOG4108ZC9 flagellar basal-body rod protein flgc DYQ48_10290 ENOG4107R88 Chemotaxis protein (CheV) DYQ48_10310 ENOG4105BZU Histidine kinase DYQ48_10315 ENOG4105BZU Histidine kinase DYQ48_10325 ENOG4105BZU Histidine kinase DYQ48_10350 ENOG41075W9 High frequency lysogenization protein HflD homolog DYQ48_10355 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) DYQ48_10365 ENOG4105KAE Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) DYQ48_10370 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit DYQ48_10375 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) DYQ48_10380 ENOG4108R4Z Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity) DYQ48_10390 ENOG4105C3M thioredoxin reductase DYQ48_10395 ENOG4105CNU cell division protein FtsK DYQ48_10405 ENOG4107Y7W Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity) DYQ48_10410 ENOG4105D1H recombination factor protein RarA DYQ48_10415 ENOG41082MI Protein CrcB homolog DYQ48_10420 ENOG4105CHU acetyl-coa acetyltransferase DYQ48_10435 ENOG4108UGX Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity) DYQ48_10440 ENOG4105C55 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs DYQ48_10450 ENOG4105HSZ Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity) DYQ48_10460 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) DYQ48_10465 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) DYQ48_10470 ENOG4105CVM Molybdenum cofactor synthesis domain protein DYQ48_10475 ENOG4105D06 uba thif-type nad fad binding protein DYQ48_10485 ENOG4105CGK Exodeoxyribonuclease III DYQ48_10495 ENOG4105CVM Molybdenum cofactor synthesis domain protein DYQ48_10500 ENOG41085AN Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) DYQ48_10510 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) DYQ48_10520 ENOG4105I5W Transporter DYQ48_10535 ENOG4108IFG nitrite reductase, (NAD(P)H) DYQ48_10550 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) DYQ48_10575 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase DYQ48_10585 ENOG4105D5U fad dependent oxidoreductase DYQ48_10600 ENOG4108N8X transition metal ion binding DYQ48_10640 ENOG4105ETX regulatoR DYQ48_10650 ENOG4107SCK Monooxygenase DYQ48_10680 ENOG4105CQZ Histidine kinase DYQ48_10685 ENOG4105E0F Histidine kinase DYQ48_10715 ENOG4105FFC UPF0187 protein DYQ48_10755 ENOG4105C8Q Methyl-accepting chemotaxis DYQ48_10765 ENOG4105EXG Transcriptional regulator DYQ48_10780 ENOG4105EWI Short-chain dehydrogenase reductase Sdr DYQ48_10810 ENOG4105CGY Dna recombination protein DYQ48_10845 ENOG41090A4 Pterin carbinolamine dehydratase DYQ48_10915 ENOG4105EI2 Pseudouridine synthase DYQ48_10920 ENOG4105C03 ribonuclease DYQ48_10925 ENOG4105WH1 Two component transcriptional regulator luxr family DYQ48_10940 ENOG4108V1T peptidylprolyl cis-trans isomerase DYQ48_10950 ENOG4107QQG Dehydrogenase DYQ48_10995 ENOG4105CET Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity) DYQ48_11000 ENOG4105CHD Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity) DYQ48_11005 ENOG4105BZ1 (ABC) transporter DYQ48_11020 ENOG4108EC8 DNA internalization-related competence protein ComEC DYQ48_11030 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) DYQ48_11035 ENOG4105D60 lipoprotein releasing system transmembrane protein DYQ48_11045 ENOG410681N tpr repeat protein DYQ48_11070 ENOG410612Q succinate dehydrogenase (cytochrome b-556 subunit) DYQ48_11080 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) DYQ48_11095 ENOG4105CHC glucokinase (EC 2.7.1.2) DYQ48_11100 ENOG4108Q79 6-phosphogluconolactonase (EC 3.1.1.31) DYQ48_11105 ENOG4105C01 Dihydroxy-acid dehydratase DYQ48_11110 ENOG4108UHU Aldolase DYQ48_11145 ENOG4106RE7 Cytochrome DYQ48_11185 ENOG4105BZU Histidine kinase DYQ48_11195 ENOG4105BZM domain protein DYQ48_11220 ENOG4105D1N poly(r)-hydroxyalkanoic acid synthase, class DYQ48_11230 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase DYQ48_11250 ENOG4105CF9 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity) DYQ48_11265 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) DYQ48_11270 ENOG4108Z6B deaminase DYQ48_11275 ENOG4105KST dependent repressor DYQ48_11280 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) DYQ48_11330 ENOG4106F59 XRE family Transcriptional regulator DYQ48_11510 ENOG4105DFP Integrase DYQ48_11520 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) DYQ48_11525 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) DYQ48_11530 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) DYQ48_11540 ENOG4105CKD glutathione-regulated potassium-efflux system protein DYQ48_11545 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase DYQ48_11555 ENOG4105ESV Glycosyl transferase, family 4 DYQ48_11560 ENOG4105CFV Tetratricopeptide repeat protein DYQ48_11570 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) DYQ48_11575 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) DYQ48_11580 ENOG4105CAT Cytidine monophosphate kinase DYQ48_11585 ENOG4105YK5 50S ribosomal protein L36 DYQ48_11595 ENOG4105DWY Agmatine deiminase DYQ48_11625 ENOG4105DRS transport system, permease DYQ48_11630 ENOG4105F0P binding-protein-dependent transport systems inner membrane Component DYQ48_11635 ENOG4105XN3 extracellular solute-binding protein family 1 DYQ48_11660 ENOG4105K9H YciI-like protein DYQ48_11665 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) DYQ48_11670 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) DYQ48_11675 ENOG4105FE9 pseudouridine synthase DYQ48_11695 ENOG4105CZ7 nitrilase cyanide hydratase and apolipoprotein n-acyltransferase DYQ48_11700 ENOG4105CHM Aminotransferase DYQ48_11705 ENOG4107EV4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity) DYQ48_11710 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) DYQ48_11715 ENOG41060IM Heme exporter protein DYQ48_11725 ENOG4108ZKK Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity) DYQ48_11730 ENOG4105DA4 cytochrome c-type biogenesis protein DYQ48_11740 ENOG4105KWW Biogenesis protein DYQ48_11745 ENOG4108M1T Cytochrome c-type biogenesis protein DYQ48_11765 ENOG4108JJ8 (ABC) transporter DYQ48_11770 ENOG4108JJ9 ABC, transporter DYQ48_11775 ENOG4105C4M (Ubiquinol oxidase) subunit I DYQ48_11780 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii DYQ48_11815 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) DYQ48_11830 ENOG4105CH7 arginosuccinase DYQ48_11845 ENOG4105CAS nag kinase DYQ48_11855 ENOG4105CDH Citrulline--aspartate ligase DYQ48_11860 ENOG4105DBV ornithine carbamoyltransferase DYQ48_11875 ENOG4105C8N cysteinyl-tRNA synthetase DYQ48_11880 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) DYQ48_11890 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters DYQ48_11900 ENOG4105CD3 dihydroorotase DYQ48_11915 ENOG4105CPD ethanolamine ammonia-lyase DYQ48_11920 ENOG4107FQ9 ethanolamine ammonia-lyase DYQ48_11980 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) DYQ48_11985 ENOG4108HWB Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) DYQ48_11990 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) DYQ48_12005 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein DYQ48_12010 ENOG4105BZU Histidine kinase DYQ48_12025 ENOG4105ECY inositol monophosphatase DYQ48_12030 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) DYQ48_12055 ENOG4105C02 permease DYQ48_12065 ENOG4105CXB phosphoribosylaminoimidazole synthetase DYQ48_12070 ENOG4108V3E phosphoribosylglycinamide formyltransferase DYQ48_12100 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) DYQ48_12110 ENOG4105C2X Arabinose 5-phosphate isomerase DYQ48_12115 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase DYQ48_12125 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA DYQ48_12130 ENOG4108IUZ ABC transporter DYQ48_12135 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) DYQ48_12140 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA DYQ48_12145 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN DYQ48_12150 ENOG4105D1C Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity) DYQ48_12155 ENOG4105C21 Displays ATPase and GTPase activities (By similarity) DYQ48_12165 ENOG41080Z8 PHOSPHOCARRIER protein DYQ48_12170 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) DYQ48_12180 ENOG4105CJW magnesium transporter DYQ48_12185 ENOG4107UWA esterase DYQ48_12190 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii DYQ48_12195 ENOG4105C4M (Ubiquinol oxidase) subunit I DYQ48_12205 ENOG4105C85 amino acid DYQ48_12210 ENOG4108NFF pectate lyase DYQ48_12225 ENOG4105CUB amino acid DYQ48_12230 ENOG4108MHS Lysyl endopeptidase DYQ48_12275 ENOG4108Z4X TRANSCRIPTIONal DYQ48_12285 ENOG4106032 Glutathionylspermidine synthase DYQ48_12310 ENOG4108P9J Phage shock protein A DYQ48_12320 ENOG4105M4B Catalyzes the transfer of an acetyl group from acetyl- CoA to the 6'-amino group of aminoglycoside molecules conferring resistance to antibiotics containing the purpurosamine ring (By similarity) DYQ48_12325 ENOG4108S7T Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity) DYQ48_12330 ENOG4105KHV Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) DYQ48_12335 ENOG4105D49 3-dehydroquinate synthase DYQ48_12345 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) DYQ48_12350 ENOG4105C5H ABC transporter DYQ48_12355 ENOG4105C1J atp-dependent rna helicase DYQ48_12360 ENOG4109003 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity) DYQ48_12365 ENOG4105CNG UPF0061 protein DYQ48_12375 ENOG4108RXX maleylacetoacetate isomerase DYQ48_12380 ENOG4105VEQ Cold shock protein DYQ48_12390 ENOG4108VWS Yaeq family DYQ48_12395 ENOG4105CBX hi0933 family DYQ48_12400 ENOG4105BZU Histidine kinase DYQ48_12410 ENOG4105D0M Protease HtpX homolog DYQ48_12415 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) DYQ48_12420 ENOG4105CHR reductase DYQ48_12440 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) DYQ48_12445 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase DYQ48_12455 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) DYQ48_12460 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) DYQ48_12475 ENOG4105E6M Sulphatase-modifying factor protein DYQ48_12505 ENOG4108V3W Chemotaxis protein, CheW DYQ48_12510 ENOG4105C8Q Methyl-accepting chemotaxis DYQ48_12520 ENOG4107QRT dEAD DEAH box helicase DYQ48_12530 ENOG4105KB2 stringent starvation protein b DYQ48_12535 ENOG4107MKT Stringent starvation protein a DYQ48_12545 ENOG4105EIX cytochrome c1 DYQ48_12550 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) DYQ48_12555 ENOG4108R5F Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) DYQ48_12560 ENOG4105E4C Lytic transglycosylase catalytic DYQ48_12575 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) DYQ48_12580 ENOG4105C9A Phoh family DYQ48_12600 ENOG4108JU5 Magnesium and cobalt efflux protein DYQ48_12630 ENOG4105D38 putrescine abc transporter DYQ48_12635 ENOG4105F38 ABC transporter, permease DYQ48_12645 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) DYQ48_12670 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) DYQ48_12685 ENOG4105CFQ glutamine synthetase DYQ48_12690 ENOG4105CJP fad dependent oxidoreductase DYQ48_12700 ENOG4105BZU Histidine kinase DYQ48_12725 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit DYQ48_12730 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) DYQ48_12735 ENOG4105FCD Major Facilitator DYQ48_12750 ENOG4106BRA Membrane DYQ48_12755 ENOG4105BZU Histidine kinase DYQ48_12760 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase DYQ48_12765 ENOG4105C0R drug resistance transporter emrb qaca subfamily DYQ48_12775 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family DYQ48_12780 ENOG4105E1F short-chain dehydrogenase reductase DYQ48_12790 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase DYQ48_12800 ENOG4105DQ4 alcohol dehydrogenase DYQ48_12835 ENOG4105C7I Dehydrogenase DYQ48_12845 ENOG4105C1P efflux transporter, rnd family, mfp subunit DYQ48_12850 ENOG4105BZS acriflavin resistance protein DYQ48_12855 ENOG4105ETE Transcriptional regulator (LacI family DYQ48_12860 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) DYQ48_12865 ENOG4105DE4 1-phosphofructokinase DYQ48_12870 ENOG4105DM4 PTS System DYQ48_12935 ENOG4107QT7 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) DYQ48_12940 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) DYQ48_12945 ENOG4105VIE preprotein translocase, subunit YajC DYQ48_12950 ENOG4105C6U Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity) DYQ48_12955 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) DYQ48_12995 ENOG4105CZ5 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity) DYQ48_13000 ENOG4105E08 Glycoside hydrolase, family 9 DYQ48_13010 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) DYQ48_13015 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding DYQ48_13030 ENOG4108ZEF Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity) DYQ48_13035 ENOG4106H78 methyltransferase DYQ48_13040 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) DYQ48_13155 ENOG4107QTZ amino acid DYQ48_13170 ENOG4105DC7 peptidase M24 DYQ48_13180 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) DYQ48_13195 ENOG41080HI glycine oxidase DYQ48_13200 ENOG4105CTU Proline racemase DYQ48_13210 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) DYQ48_13215 ENOG4105CEN a g-specific adenine glycosylase DYQ48_13245 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) DYQ48_13265 ENOG4105QNF Outer membrane lipoprotein DYQ48_13275 ENOG4105CSU acyl-Coa dehydrogenase DYQ48_13285 ENOG4105C2V Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity) DYQ48_13305 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase DYQ48_13310 ENOG4108JMX Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) DYQ48_13315 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) DYQ48_13340 ENOG4108NQK Catalyzes the transfer of a glucuronic acid (GlcA) residue from UDP-glucuronate to mannose-alpha-1,3-glucose-beta- 1,4-glucose-P-P-polyisoprenyl to form the lipid-linked tetrasaccharide GlcA-Man-Glc(2)-PP-Pol, with a glucuronic acid- beta-mannose linkage. Is involved in the biosynthesis of the exopolysaccharide xanthan, since it catalyzes the fourth glycosylation step in the assembly of the pentasaccharide-P-P- polyisoprenyl repeating unit of xanthan. Is unable to use the trisaccharide acceptor freed from the pyrophosphate lipid moiety. Does not show specificity for the lipidic portion of the acceptor. Shows diminished activity when tested with 6-O-acetyl-mannose- alpha-1,3-glucose-beta-1,4-glucose-P-P-polyisoprenyl, a DYQ48_13350 ENOG4107Y2G Glycosyl transferase (Group 1 DYQ48_13375 ENOG4105D3Q Sugar transferase DYQ48_13395 ENOG4105WJX transcriptional regulator MERR family DYQ48_13400 ENOG4108ZUF This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) DYQ48_13405 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) DYQ48_13410 ENOG4105CSS phenylalanyl-tRNA synthetase (alpha subunit) DYQ48_13415 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) DYQ48_13420 ENOG41082NX 50s ribosomal protein l35 DYQ48_13425 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) DYQ48_13430 ENOG4105C22 threonyL-tRNA synthetase DYQ48_13495 ENOG4106E4H Type IV secretory pathway VirB3 family protein DYQ48_13515 ENOG4105CMA conjugation trbi family protein DYQ48_13555 ENOG4105X0D Fimbrial protein DYQ48_13595 ENOG4105EWT decarboxylase family DYQ48_13600 ENOG4108KPZ tonB-dependent Receptor DYQ48_13600 ENOG4108KPZ tonB-dependent Receptor DYQ48_13605 ENOG41076UM multiple antibiotic resistance (MarC)-related protein DYQ48_13615 ENOG4105M2J Glutaredoxin DYQ48_13620 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) DYQ48_13625 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit DYQ48_13630 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) DYQ48_13640 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase DYQ48_13660 ENOG4105K77 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity) DYQ48_13665 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) DYQ48_13670 ENOG4105KG7 Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity) DYQ48_13675 ENOG4107QHU One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity) DYQ48_13680 ENOG4105CHV Transcription elongation factor NusA DYQ48_13685 ENOG4105K7D Required for maturation of 30S ribosomal subunits (By similarity) DYQ48_13695 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) DYQ48_13700 ENOG4105C8S subunit m DYQ48_13725 ENOG4105CMZ NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity) DYQ48_13730 ENOG4107R0R NADH dehydrogenase subunit g DYQ48_13735 ENOG4107QIZ NADH dehydrogenase DYQ48_13740 ENOG4105GKE subunit e DYQ48_13750 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain DYQ48_13755 ENOG4105ES3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) DYQ48_13760 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain DYQ48_13775 ENOG4105CP7 Triose-phosphate isomerase DYQ48_13780 ENOG4105EMU Dehydrogenase DYQ48_13805 ENOG4105BZU Histidine kinase DYQ48_13820 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) DYQ48_13825 ENOG4107QTG Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity) DYQ48_13850 ENOG4108ZGB N-(5'-phosphoribosyl)anthranilate isomerase DYQ48_13870 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) DYQ48_13875 ENOG4105C5I Dehydrogenase DYQ48_13890 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) DYQ48_13900 ENOG4105DJ4 phosphatidylserine decarboxylase DYQ48_13910 ENOG4105D7A ATP-binding protein DYQ48_13955 ENOG4107QK4 glycoside hydrolase, family 3 domain protein DYQ48_13975 ENOG4108RRZ Transcription elongation factor GreB DYQ48_13980 ENOG4105CBM Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity) DYQ48_14005 ENOG4105DHP deoxycytidine triphosphate deaminase DYQ48_14015 ENOG4105D1F ATP-binding protein DYQ48_14040 ENOG4105C9K Endothelin-converting enzyme 1 DYQ48_14065 ENOG4105DC8 reductase DYQ48_14075 ENOG4108YZY peptidylprolyl cis-trans isomerase DYQ48_14080 ENOG4105K4H Nlp p60 protein DYQ48_14085 ENOG4105K4H Nlp p60 protein DYQ48_14100 ENOG4105CK2 sodium dicarboxylate symporter DYQ48_14105 ENOG4105G6Z alkaline phosphatase DYQ48_14110 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) DYQ48_14115 ENOG41067QG Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) DYQ48_14120 ENOG4105CTB Polyprenyl synthetase DYQ48_14135 ENOG4105CMS peptidase U62, modulator of DNA gyrase DYQ48_14140 ENOG4105N42 UPF0307 protein DYQ48_14145 ENOG4105D1U peptidase U62 modulator of DNA gyrase DYQ48_14155 ENOG4105QD6 exported protein DYQ48_14160 ENOG4105C03 ribonuclease DYQ48_14180 ENOG4108UXA Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity) DYQ48_14200 ENOG4108Z1W Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity) DYQ48_14215 ENOG4105C8T Leucyl-tRNA synthetase DYQ48_14225 ENOG4107QR8 Thioredoxin DYQ48_14235 ENOG4105CDV Ompa motb domain protein DYQ48_14240 ENOG4105CVP deoxyribo-dipyrimidine photolyase DYQ48_14250 ENOG4105CDU Replicative dna helicase DYQ48_14260 ENOG4105CAQ asparagine synthetase DYQ48_14265 ENOG4108K3A Glutathione S-transferase DYQ48_14275 ENOG4105C1G acyl-Coa dehydrogenase DYQ48_14290 ENOG4105F8V Hydrolase, tatD family DYQ48_14295 ENOG4105CUZ uba thif-type nad fad binding protein DYQ48_14310 ENOG4105VEQ Cold shock protein DYQ48_14320 ENOG4105HDD phospholipase DYQ48_14330 ENOG4108V9Q carbonic anhydrase DYQ48_14345 ENOG4107GFK fumarate DYQ48_14355 ENOG4105DP0 ferredoxin-NADP reductase DYQ48_14365 ENOG4105DGW oligopeptidase A DYQ48_14395 ENOG4105DUX Transporter DYQ48_14420 ENOG4105C0R drug resistance transporter emrb qaca subfamily DYQ48_14425 ENOG4105CW7 secretion protein, HlyD family DYQ48_14445 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) DYQ48_14450 ENOG4105FQ6 thiopurine methyltransferase DYQ48_14455 ENOG4108UWD Iron-storage protein DYQ48_14465 ENOG4108ESX Receptor DYQ48_14475 ENOG4105CAQ asparagine synthetase DYQ48_14480 ENOG4105C9Y Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity) DYQ48_14485 ENOG4105KUZ arsenate reductase DYQ48_14500 ENOG4105E1P Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity) DYQ48_14505 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) DYQ48_14545 ENOG4105CE9 30S ribosomal protein S2 DYQ48_14550 ENOG4105CU7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity) DYQ48_14555 ENOG4105BZU Histidine kinase DYQ48_14560 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) DYQ48_14565 ENOG4108VCV Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) DYQ48_14570 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) DYQ48_14575 ENOG4105KNE Phosphatidate cytidylyltransferase DYQ48_14580 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) DYQ48_14585 ENOG4105DZP Membrane-associated zinc metalloprotease DYQ48_14600 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) DYQ48_14605 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) DYQ48_14610 ENOG4105DAF Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) DYQ48_14615 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) DYQ48_14620 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) DYQ48_14630 ENOG4107QM9 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity) DYQ48_14640 ENOG4108YXA Membrane DYQ48_14715 ENOG4107QK5 Homocysteine s-methyltransferase DYQ48_14720 ENOG4108IQI permease DYQ48_14725 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase DYQ48_14730 ENOG4105DA5 (ABC) transporter DYQ48_14745 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) DYQ48_14755 ENOG4108R3D Electron transport complex DYQ48_14770 ENOG4105K6V RNA polymerase DYQ48_14815 ENOG4105M4H endoribonuclease L-psp DYQ48_14860 ENOG4105F27 Major Facilitator DYQ48_14865 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase DYQ48_14880 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA DYQ48_14890 ENOG4108YZY peptidylprolyl cis-trans isomerase DYQ48_14895 ENOG4105DFF Rod shape-determining protein mreb DYQ48_14915 ENOG4105EMN RNA polymerase sigma factor DYQ48_14930 ENOG4105KSC Transcriptional regulator, TraR DksA family DYQ48_14945 ENOG4108VKG metal-dependent hydrolase DYQ48_14965 ENOG4105CHU acetyl-coa acetyltransferase DYQ48_14980 ENOG4105BZU Histidine kinase DYQ48_14995 ENOG4107T0X DNA ligase DYQ48_15005 ENOG4107T0X DNA ligase DYQ48_15010 ENOG4107QRT dEAD DEAH box helicase DYQ48_15025 ENOG4105VEQ Cold shock protein DYQ48_15030 ENOG4107RHB Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity) DYQ48_15035 ENOG4108UGV hypoxanthine phosphoribosyltransferase DYQ48_15040 ENOG4107QPA Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity) DYQ48_15045 ENOG4105EXX Deoxyribodipyrimidine photolyase-related protein DYQ48_15050 ENOG4105EWK phytoene DYQ48_15055 ENOG4107ZXU DSBA oxidoreductase DYQ48_15060 ENOG41080ZE Adenylate cyclase DYQ48_15075 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) DYQ48_15080 ENOG4105EFQ Two component transcriptional regulator (Winged helix family DYQ48_15085 ENOG41071DT Involved in DNA repair and RecF pathway recombination (By similarity) DYQ48_15090 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) DYQ48_15095 ENOG4108ZBM Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity) DYQ48_15105 ENOG4105C3F Signal peptidase i DYQ48_15110 ENOG4105C4S Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity) DYQ48_15115 ENOG4105C0H protease DYQ48_15125 ENOG4105EMN RNA polymerase sigma factor DYQ48_15130 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase DYQ48_15140 ENOG4107RDJ Sulfotransferase DYQ48_15170 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase DYQ48_15175 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase DYQ48_15180 ENOG4105E39 Enoyl-CoA hydratase DYQ48_15185 ENOG4105C1G acyl-Coa dehydrogenase DYQ48_15190 ENOG4105C26 Dehydrogenase DYQ48_15205 ENOG4106FKC arabinogalactan endo-1,4-beta-galactosidase DYQ48_15210 ENOG4105CNT hydrolase family 2 DYQ48_15215 ENOG4105CMJ mandelate racemase muconate lactonizing DYQ48_15220 ENOG4105CK2 sodium dicarboxylate symporter DYQ48_15245 ENOG4105CPU Monooxygenase DYQ48_15280 ENOG4105D86 that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity) DYQ48_15290 ENOG4105C1X Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity) DYQ48_15300 ENOG4105VEJ Heat shock protein DYQ48_15305 ENOG4107QJQ Mate efflux family protein DYQ48_15310 ENOG4108YY1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity) DYQ48_15315 ENOG4105D6X Specifically methylates guanosine-37 in various tRNAs (By similarity) DYQ48_15325 ENOG4105K5M 30s ribosomal protein S16 DYQ48_15345 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY DYQ48_15355 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) DYQ48_15390 ENOG4105CZZ Alpha-N-arabinofuranosidase (EC 3.2.1.55) DYQ48_15420 ENOG4105BZU Histidine kinase DYQ48_15425 ENOG4105BZU Histidine kinase DYQ48_15430 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) DYQ48_15435 ENOG4105C08 Histidine kinase DYQ48_15440 ENOG4105KCV RNA signal recognition particle 4.5S RNA DYQ48_15465 ENOG4105BZU Histidine kinase DYQ48_15475 ENOG4105QD0 anti-sigma regulatory factor serine threonine protein kinase DYQ48_15480 ENOG4105FUA antagonist DYQ48_15485 ENOG4107MMM Anti-sigma-factor antagonist DYQ48_15490 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase DYQ48_15505 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) DYQ48_15520 ENOG4105KAF membrAne DYQ48_15525 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) DYQ48_15535 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) DYQ48_15540 ENOG4105CCU oxidase (Subunit III) DYQ48_15545 ENOG4105BZ9 Cytochrome C oxidase, subunit I DYQ48_15550 ENOG4105E2S oxidase) subunit II DYQ48_15560 ENOG4105C48 Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity) DYQ48_15565 ENOG4105M02 This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity) DYQ48_15575 ENOG4105DTN riboflavin biosynthesis protein ribF DYQ48_15580 ENOG4105CJR Integral membrane protein (MviN DYQ48_15585 ENOG4105KQV Binds directly to 16S ribosomal RNA (By similarity) DYQ48_15600 ENOG4105KK9 This protein binds to 23S rRNA in the presence of protein L20 (By similarity) DYQ48_15605 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) DYQ48_15610 ENOG4108TGP Thioesterase superfamily protein DYQ48_15620 ENOG4105UPE Enoyl-CoA hydratase DYQ48_15625 ENOG4105C29 acyl-CoA thioesterase DYQ48_15635 ENOG4105GFR rna polymerase sigma factor DYQ48_15655 ENOG4105DWA May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate DYQ48_15675 ENOG4108EF9 Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR DYQ48_15720 ENOG4105WH1 Two component transcriptional regulator luxr family DYQ48_15725 ENOG4105BZU Histidine kinase DYQ48_15745 ENOG4107QMS site-determining protein DYQ48_15750 ENOG4105VJP Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity) DYQ48_15760 ENOG4105US7 Histidine kinase DYQ48_15765 ENOG4105ETX regulatoR DYQ48_15780 ENOG4105DIJ Phosphoethanolamine transferase DYQ48_15805 ENOG4105C2C drug resistance transporter, Bcr CflA DYQ48_15810 ENOG4105CBI The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor DYQ48_15820 ENOG4105EBR Carboxylesterase DYQ48_15825 ENOG4105CV8 reductase DYQ48_15845 ENOG4106AXJ AraC family transcriptional regulator DYQ48_15855 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein DYQ48_15865 ENOG4105EPD Oligopeptide transporter, Opt family DYQ48_15915 ENOG4105D6F Phosphatase DYQ48_15935 ENOG4107XKX isoquinoline 1-oxidoreductase, alpha subunit DYQ48_15940 ENOG4105DIP Molybdopterin dehydrogenase FAD-binding DYQ48_15945 ENOG4105C7W Xanthine dehydrogenase DYQ48_15950 ENOG4107QK4 glycoside hydrolase, family 3 domain protein DYQ48_15995 ENOG4105CWX Alpha-1,2-mannosidase DYQ48_16005 ENOG4105CYX Short-chain dehydrogenase reductase Sdr DYQ48_16020 ENOG4107Z4K Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) DYQ48_16025 ENOG4105CVJ phosphoglycerate mutase DYQ48_16095 ENOG4105DZR Type I site-specific deoxyribonuclease DYQ48_16110 ENOG4105CVR type I restriction-modification system DYQ48_16140 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis DYQ48_16160 ENOG4105EPW hflc protein DYQ48_16165 ENOG4107QJR hflk protein DYQ48_16170 ENOG4105M3Z response regulator DYQ48_16195 ENOG4108JQB penicillin-binding protein 1C DYQ48_16215 ENOG4105DN3 alpha-2-macroglobulin domain protein DYQ48_16230 ENOG4105C7F AcnD-accessory protein PrpF DYQ48_16235 ENOG4108I0Z Aconitate hydratase DYQ48_16240 ENOG4105BZN citrate synthase DYQ48_16245 ENOG4105CR4 methylisocitrate lyase DYQ48_16250 ENOG4108JU7 Transcriptional regulator DYQ48_16260 ENOG4105VTW prevent-host-death family DYQ48_16265 ENOG4105KRQ Addiction module toxin, Txe YoeB family DYQ48_16280 ENOG4107QRG dna polymerase iii DYQ48_16285 ENOG4105HHA aminodeoxychorismate lyase DYQ48_16295 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) DYQ48_16300 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) DYQ48_16305 ENOG4105CHR reductase DYQ48_16310 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase DYQ48_16320 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) DYQ48_16325 ENOG4105VGS 50s ribosomal protein l32 DYQ48_16330 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein DYQ48_16335 ENOG4108UHJ MAF-like protein DYQ48_16350 ENOG4105C7R Atpase associated with various cellular activities aaa_3 DYQ48_16360 ENOG4105F8C transglutaminase domain-containing protein DYQ48_16370 ENOG4105K59 histidine triad (HIT) protein DYQ48_16380 ENOG4105KDX Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity) DYQ48_16385 ENOG4107QMP dna polymerase iii subunits gamma and tau DYQ48_16510 ENOG4108ZAF Molybdopterin DYQ48_16515 ENOG4105M00 molybdopterin converting factor, subunit 1 DYQ48_16525 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) DYQ48_16530 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) DYQ48_16535 ENOG4108W7E Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity) DYQ48_16540 ENOG4105DKP glycosyl transferase, family 9 DYQ48_16555 ENOG4108ZF3 Phosphatase DYQ48_16560 ENOG4108JDX DNA polymerase iii, epsilon subunit DYQ48_16565 ENOG4108UMW Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) DYQ48_16575 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) DYQ48_16585 ENOG4105EIN peptidylprolyl cis-trans isomerase DYQ48_16615 ENOG4105CHN ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity) DYQ48_16620 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) DYQ48_16625 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation DYQ48_16675 ENOG4105ED4 portal protein DYQ48_16940 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) DYQ48_16950 ENOG4105VW4 glutaredoxin 3 DYQ48_16955 ENOG4105ERG peptidase m48, ste24p DYQ48_16960 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DYQ48_16965 ENOG4105BZU Histidine kinase DYQ48_16970 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) DYQ48_16975 ENOG4105C9X ppx gppa phosphatase DYQ48_16980 ENOG4105BZF Glycosyl transferase (Group 1 DYQ48_16985 ENOG4105EYK Phosphatidylglycerophosphatase B DYQ48_16990 ENOG4105F10 Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity) DYQ48_17000 ENOG4108YP4 Metalloprotease, specifically cleaves on the N-terminal side of aspartyl, glutamyl and cysteic acid residues (By similarity) DYQ48_17005 ENOG4105ED9 Protein of unknown function (DUF455) DYQ48_17010 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase DYQ48_17025 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase DYQ48_17035 ENOG4105CVJ phosphoglycerate mutase DYQ48_17045 ENOG4105HSS phospholipase C DYQ48_17060 ENOG4105CPQ Dehydrogenase DYQ48_17070 ENOG4108IJ6 ABC transporter DYQ48_17080 ENOG4108I5D sulfate abc transporter DYQ48_17085 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein DYQ48_17090 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) DYQ48_17100 ENOG4108R99 pseudouridine synthase DYQ48_17110 ENOG4105F37 PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6 DYQ48_17120 ENOG4105CIS alcohol dehydrogenase DYQ48_17125 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase DYQ48_17140 ENOG4108K3A Glutathione S-transferase DYQ48_17145 ENOG4105D9Z Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) DYQ48_17150 ENOG4107XH4 PPIases accelerate the folding of proteins (By similarity) DYQ48_17165 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) DYQ48_17175 ENOG4105C7V phospho-2-dehydro-3-deoxyheptonate aldolase DYQ48_17180 ENOG41080I0 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity) DYQ48_17190 ENOG4108ZT0 50S ribosomal protein l17 DYQ48_17195 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) DYQ48_17200 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) DYQ48_17205 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) DYQ48_17210 ENOG4108Z04 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits DYQ48_17215 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) DYQ48_17220 ENOG4108UZ0 Binds to the 23S rRNA (By similarity) DYQ48_17230 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) DYQ48_17240 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) DYQ48_17245 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) DYQ48_17250 ENOG4105VBI Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity) DYQ48_17255 ENOG4105CW6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits DYQ48_17260 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) DYQ48_17265 ENOG4108UNN Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity) DYQ48_17270 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal DYQ48_17280 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) DYQ48_17285 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) DYQ48_17295 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) DYQ48_17300 ENOG4105CFD One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity DYQ48_17305 ENOG41080KG One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) DYQ48_17310 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) DYQ48_17315 ENOG4105EEE One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity) DYQ48_17320 ENOG4108Z10 Involved in the binding of tRNA to the ribosomes (By similarity) DYQ48_17325 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) DYQ48_17335 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) DYQ48_17340 ENOG4108UKE Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity) DYQ48_17355 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) DYQ48_17360 ENOG4108VZM 50s ribosomal protein L10 DYQ48_17365 ENOG4105C64 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity) DYQ48_17370 ENOG4108UIK This protein binds directly to 23S ribosomal RNA (By similarity) DYQ48_17375 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) DYQ48_17380 ENOG4105PM1 preprotein translocase subunit SecE DYQ48_17390 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) DYQ48_17455 ENOG4105DFP Integrase DYQ48_17460 ENOG4105C3G gtp-binding protein DYQ48_17465 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) DYQ48_17470 ENOG4105KW6 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity) DYQ48_17475 ENOG4105C5T Phosphoribosyl pyrophosphate synthase DYQ48_17485 ENOG4105CTR Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) DYQ48_17490 ENOG4105QVB outer membrane lipoprotein LolB DYQ48_17495 ENOG4105DJQ tetratricopeptide tpr_2 repeat protein DYQ48_17520 ENOG4108RIR Molybdenum cofactor biosynthesis protein DYQ48_17525 ENOG4105CSR polyphosphate kinase 2 DYQ48_17540 ENOG4107QX9 Thiol disulfide interChange protein DYQ48_17545 ENOG4107S2Z UPF0761 membrane protein DYQ48_17550 ENOG4105CS1 NAD(P)H quinone oxidoreductase DYQ48_17565 ENOG4108Z66 YbaK ebsC protein DYQ48_17570 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin DYQ48_17580 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin DYQ48_17585 ENOG4105CM2 brancheD-chain amino acid aminotransferase DYQ48_17635 ENOG4105C2M dna polymerase I DYQ48_17655 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) DYQ48_17670 ENOG4105C5Q Transcriptional regulator DYQ48_17675 ENOG4105NXH GreA GreB family elongation factor DYQ48_17680 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) DYQ48_17690 ENOG4107QXP Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) DYQ48_17700 ENOG4105WH1 Two component transcriptional regulator luxr family DYQ48_17705 ENOG4105BZU Histidine kinase DYQ48_17710 ENOG4105BZU Histidine kinase DYQ48_17725 ENOG4105CX6 glutaminyL-tRNA synthetase DYQ48_17730 ENOG4105DXC membrane DYQ48_17775 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase DYQ48_17785 ENOG4105CEY Amp-dependent synthetase and ligase DYQ48_17790 ENOG4105DDW LysR family Transcriptional regulator DYQ48_17825 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family DYQ48_17830 ENOG4105D0A hydroxylase DYQ48_17840 ENOG4108WBT adenosyltransferase DYQ48_17850 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) DYQ48_17855 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) DYQ48_17860 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) DYQ48_17865 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) DYQ48_17870 ENOG4105NWN ApaG protein DYQ48_17875 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) DYQ48_17880 ENOG4108UZX fmn reductase DYQ48_17885 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) DYQ48_17895 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component DYQ48_17900 ENOG4105D7T ABC transporter DYQ48_17905 ENOG4107T8P acyl-Coa dehydrogenase DYQ48_17920 ENOG4105C3B Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity) DYQ48_17940 ENOG41080IJ Diacylglycerol kinase DYQ48_17950 ENOG4105DHQ Histidine kinase DYQ48_17955 ENOG4105ETX regulatoR DYQ48_17960 ENOG4108UJV acyl-CoA thioesterase i DYQ48_17965 ENOG4108I0Y (ABC) transporter DYQ48_17990 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component DYQ48_18055 ENOG4105D05 Receptor DYQ48_18065 ENOG4105CPC Aldo Keto reductase DYQ48_18070 ENOG4105D9N nucleoside DYQ48_18085 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) DYQ48_18090 ENOG4107R6G Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity) DYQ48_18100 ENOG4105CPH Catalyzes the formation of S-adenosylmethionine from methionine and ATP DYQ48_18105 ENOG4105D6F Phosphatase DYQ48_18110 ENOG4105F37 PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6 DYQ48_18130 ENOG4105CCA Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity) DYQ48_18140 ENOG4105C3E May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity) DYQ48_18205 ENOG4105SYT Methylenetetrahydrofolate reductase DYQ48_18225 ENOG4105M6F mutator MutT protein DYQ48_18235 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving DYQ48_18240 ENOG4105DR5 peptidase DYQ48_18250 ENOG4105C7C involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) DYQ48_18255 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) DYQ48_18265 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) DYQ48_18270 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) DYQ48_18275 ENOG4105CPF Cell wall formation (By similarity) DYQ48_18280 ENOG4105DFU Cell wall formation (By similarity) DYQ48_18285 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) DYQ48_18295 ENOG4105CPY First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity) DYQ48_18300 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) DYQ48_18305 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) DYQ48_18310 ENOG4105CJN penicillin-binding protein DYQ48_18315 ENOG4106932 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) DYQ48_18365 ENOG4105S2T inner membrane protein YbcI DYQ48_18370 ENOG4105CQB FAD linked oxidase domain protein DYQ48_18375 ENOG4105EEX Two component transcriptional regulator (Winged helix family DYQ48_18380 ENOG4105C08 Histidine kinase DYQ48_18385 ENOG4108R80 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity) DYQ48_18390 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) DYQ48_18395 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) DYQ48_18425 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) DYQ48_18430 ENOG4107YIM Involved in the transcription termination process (By similarity) DYQ48_18435 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) DYQ48_18445 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) DYQ48_18465 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) DYQ48_18475 ENOG4108Z11 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity) DYQ48_18480 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) DYQ48_18490 ENOG4105C5H ABC transporter DYQ48_18495 ENOG4108RBJ Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) DYQ48_18510 ENOG4107RH7 Nicotinate phosphoribosyltransferase DYQ48_18555 ENOG4106S9K Transcriptional regulator DYQ48_18590 ENOG4105GVR general secretion pathway protein D DYQ48_18600 ENOG410678M general secretion pathway protein M DYQ48_18605 ENOG41090VX general secretion pathway protein L DYQ48_18610 ENOG4105UV2 general secretion pathway protein K DYQ48_18615 ENOG41069G9 General secretion pathway protein J DYQ48_18625 ENOG4105WMT general secretion pathway protein h DYQ48_18635 ENOG4105D7Q type ii secretion system DYQ48_18640 ENOG4107QHF type ii secretion system protein e DYQ48_18645 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin DYQ48_18650 ENOG4105EUR Domain-Containing protein DYQ48_18655 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin DYQ48_18660 ENOG4105EUR Domain-Containing protein DYQ48_18665 ENOG4108ETH Formylglycinamide ribotide synthetase DYQ48_18670 ENOG4105T95 Thiol disulfide interChange protein DYQ48_18675 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) DYQ48_18690 ENOG4108K5H permease YjgP YjgQ family protein DYQ48_18700 ENOG4105BZ6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity) DYQ48_18710 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) DYQ48_18740 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase DYQ48_18770 ENOG4105DHJ ABC, transporter DYQ48_18775 ENOG4108SNX Mammalian cell entry related domain protein DYQ48_18795 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase DYQ48_18820 ENOG4107QKV phosphomannomutase DYQ48_18825 ENOG4105CJT Mannose-1-phosphate guanylyltransferase DYQ48_18830 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase DYQ48_18835 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase DYQ48_18850 ENOG4105BZJ Electron transfer flavoprotein DYQ48_18855 ENOG4105C10 Electron transfer flavoprotein DYQ48_18870 ENOG4105CKK Glycosyl transferase, family 2 DYQ48_18890 ENOG4105FAW cDP-glucose 4,6-dehydratase DYQ48_18895 ENOG4105C0K Gdp-mannose 4,6-dehydratase DYQ48_18910 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) DYQ48_18920 ENOG4105EY8 ABC transporter DYQ48_18935 ENOG4105C28 cystathionine DYQ48_18960 ENOG4105CZX twitching motility protein DYQ48_18965 ENOG4108RXX maleylacetoacetate isomerase DYQ48_18980 ENOG4105C1J atp-dependent rna helicase DYQ48_18990 ENOG4105D05 Receptor DYQ48_18995 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase DYQ48_19005 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) DYQ48_19020 ENOG4105NIV Esterase DYQ48_19025 ENOG4107RNH Outer membrane receptor FepA DYQ48_19030 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) DYQ48_19035 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) DYQ48_19040 ENOG4108RKI Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity) DYQ48_19055 ENOG4105DGW oligopeptidase A DYQ48_19100 ENOG4105IJJ transcriptional regulator, crp fnr family DYQ48_19105 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) DYQ48_19115 ENOG4105C19 ABC transporter DYQ48_19125 ENOG4107RBB ABC transporter, permease DYQ48_19130 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family DYQ48_19145 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) DYQ48_19160 ENOG4105KNM Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) DYQ48_19165 ENOG4105C4J Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity) DYQ48_19170 ENOG4105J80 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity) DYQ48_19175 ENOG4105CDG Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity) DYQ48_19180 ENOG4107S15 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) DYQ48_19185 ENOG4107Z6K F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) DYQ48_19190 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) DYQ48_19195 ENOG4107RAZ it plays a direct role in the translocation of protons across the membrane (By similarity) DYQ48_19210 ENOG4107QN2 dihydrolipoyl dehydrogenase DYQ48_19220 ENOG4107QSN dihydrolipoamide acetyltransferase DYQ48_19245 ENOG4105D01 (LipO)protein DYQ48_19250 ENOG4108UMI ABC transporter, permease DYQ48_19255 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) DYQ48_19260 ENOG4108EHX EamA-like transporter family DYQ48_19280 ENOG4107EXU Short-chain dehydrogenase reductase Sdr DYQ48_19285 ENOG4105I08 Pseudouridine synthase DYQ48_19290 ENOG4105D8J Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity) DYQ48_19315 ENOG4105BZU Histidine kinase DYQ48_19335 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) DYQ48_19340 ENOG4105MWK D-amino acid dehydrogenase, small subunit DYQ48_19345 ENOG4105EW9 transcriptional regulator AsnC family DYQ48_19370 ENOG4107RD7 Flagellar Motor Protein, MotA DYQ48_19375 ENOG4105ER2 Ompa motb domain protein DYQ48_19405 ENOG4105F2I Transposase DYQ48_19435 ENOG4108JJA ABC, transporter DYQ48_19460 ENOG4105E3A (ABC) transporter DYQ48_19465 ENOG4105DA5 (ABC) transporter DYQ48_19475 ENOG4105EEQ Na H antiporter DYQ48_19495 ENOG4108UN4 phage SPO1 DNA polymerase-related protein DYQ48_19510 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b DYQ48_19520 ENOG4105EJC lysr family transcriptional regulator DYQ48_19530 ENOG4105CPC Aldo Keto reductase DYQ48_19540 ENOG4105C9K Endothelin-converting enzyme 1 DYQ48_19565 ENOG4107QTZ amino acid DYQ48_19575 ENOG4108VAC response regulator DYQ48_19580 ENOG4105C2F Histidine kinase DYQ48_19600 ENOG4108Z9Z response to DNA damage stimulus DYQ48_19605 ENOG4105WEF catalase DYQ48_19615 ENOG4105BZU Histidine kinase DYQ48_19630 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family DYQ48_19645 ENOG4105CYX Short-chain dehydrogenase reductase Sdr DYQ48_19655 ENOG4105CMR udp-glucose 4-epimerase DYQ48_19675 ENOG4105BZ1 (ABC) transporter DYQ48_19690 ENOG4105E2A Dehydrogenase DYQ48_19710 ENOG4105CC0 LysR family Transcriptional regulator DYQ48_19715 ENOG4105F27 Major Facilitator DYQ48_19755 ENOG4105DA5 (ABC) transporter DYQ48_19770 ENOG4108UQ8 endoribonuclease L-psp DYQ48_19800 ENOG4105CHH sulfate transporter DYQ48_19835 ENOG4108IND Tetr family transcriptional regulator DYQ48_19840 ENOG4105EJC lysr family transcriptional regulator DYQ48_19845 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase DYQ48_19865 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) DYQ48_19870 ENOG4108YYA Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity) DYQ48_19875 ENOG4105D1S lipid A biosynthesis DYQ48_19880 ENOG4108Z7F N-acetyltransferase DYQ48_19885 ENOG4107T1C Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity) DYQ48_19910 ENOG4106WTF Glycosyl transferase, family 2 DYQ48_19925 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B DYQ48_19930 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) DYQ48_19935 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) DYQ48_19940 ENOG4108WZM domain protein DYQ48_19945 ENOG4105C79 DNA protecting protein DprA DYQ48_19950 ENOG4108RPN Protein smg homolog DYQ48_19965 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) DYQ48_19970 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) DYQ48_19985 ENOG4107ZQV short-chain dehydrogenase reductase DYQ48_19995 ENOG4105D07 Signal peptide peptidase, SppA DYQ48_20000 ENOG4107QI1 Mate efflux family protein DYQ48_20015 ENOG4105C25 Primosomal protein n' DYQ48_20025 ENOG4108TGY Glutathione S-transferase DYQ48_20050 ENOG4105EN6 Membrane DYQ48_20055 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) DYQ48_20060 ENOG4105D5S Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity) DYQ48_20065 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase DYQ48_20070 ENOG4105CRP Part of the ABC transporter FtsEX involved in DYQ48_20075 ENOG4105CAK Cell division ATP-binding protein ftsE DYQ48_20080 ENOG4105C1J atp-dependent rna helicase DYQ48_20085 ENOG4105K63 Thioredoxin DYQ48_20090 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) DYQ48_20110 ENOG4105VS7 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity) DYQ48_20125 ENOG4105E9K Isocitrate dehydrogenase DYQ48_20140 ENOG4107R1K Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity) DYQ48_20145 ENOG4105CH2 amidohydrolase DYQ48_20150 ENOG4105ENT Efflux transporter rnd family, mfp subunit DYQ48_20155 ENOG4105BZS acriflavin resistance protein DYQ48_20170 ENOG4105DTQ mandelate racemase muconate lactonizing DYQ48_20180 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase DYQ48_20185 ENOG4108UQS dipeptidase DYQ48_20225 ENOG4105E32 cytoplasmic protein DYQ48_20245 ENOG4105D5Q Arginine ornithine antiporter DYQ48_20260 ENOG4108Z12 YiaAB two helix domain-containing protein DYQ48_20275 ENOG4107QK4 glycoside hydrolase, family 3 domain protein DYQ48_20280 ENOG4107ZVW dihydroneopterin aldolase DYQ48_20285 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) DYQ48_20290 ENOG4105VCC 30S ribosomal protein S21 DYQ48_20295 ENOG4105KTH gatB Yqey DYQ48_20300 ENOG4107S2Z UPF0761 membrane protein DYQ48_20305 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) DYQ48_20310 ENOG4105DHU Bile acid DYQ48_20320 ENOG4105F1R Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity) DYQ48_20345 ENOG4107QS1 Cytochrome C Oxidase, Subunit III DYQ48_20350 ENOG4105FT1 Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity) DYQ48_20365 ENOG4105CV4 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity) DYQ48_20375 ENOG4105C26 Dehydrogenase DYQ48_20405 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) DYQ48_20410 ENOG4105DR5 peptidase DYQ48_20425 ENOG4108E7F Transporter DYQ48_20430 ENOG4105CGK Exodeoxyribonuclease III DYQ48_20435 ENOG4107QP2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) DYQ48_20445 ENOG4107QJE Chromosome Partitioning Protein DYQ48_20450 ENOG4105FA0 parb-like partition protein DYQ48_20465 ENOG4105CKK Glycosyl transferase, family 2 DYQ48_20485 ENOG4108Z1K This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) DYQ48_20490 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase DYQ48_20500 ENOG4105C75 arginyL-tRNA synthetase DYQ48_20510 ENOG4105EMU Dehydrogenase DYQ48_20515 ENOG4105EXC Acyl-transferase DYQ48_20525 ENOG4105CEY Amp-dependent synthetase and ligase DYQ48_20530 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) DYQ48_20535 ENOG4105CCX Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) DYQ48_20560 ENOG4108YZA Nitrogen regulatory protein pii DYQ48_20565 ENOG4105W0Z cytoplasmic protein DYQ48_20570 ENOG4105C0P Mg chelatase subunit ChlI DYQ48_20590 ENOG41066DG (EAL) domain protein DYQ48_20605 ENOG4105EJ2 Transcriptional regulator DYQ48_20640 ENOG4105ECP epimerase DYQ48_20645 ENOG4105XJC Two component transcriptional regulator (Winged helix family DYQ48_20650 ENOG4105DHQ Histidine kinase DYQ48_20670 ENOG4105C0H protease DYQ48_20690 ENOG4105DSF transport protein DYQ48_20695 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant DYQ48_20700 ENOG4105BZ6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity) DYQ48_20725 ENOG4108S01 response regulator DYQ48_20730 ENOG4108ZGX Histidine kinase DYQ48_20735 ENOG4105DJY efflux transporter, rnd family, mfp subunit DYQ48_20740 ENOG4105C19 ABC transporter DYQ48_20765 ENOG4105FDR Membrane DYQ48_20795 ENOG4105C31 Tryptophanyl-tRNA synthetase DYQ48_20800 ENOG4105VDW Csbd family DYQ48_20860 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase DYQ48_20870 ENOG4105EXZ Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity) DYQ48_20885 ENOG4105EB3 Histidine kinase DYQ48_20890 ENOG4105XJC Two component transcriptional regulator (Winged helix family DYQ48_20900 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) DYQ48_20925 ENOG4105CH6 catalase DYQ48_20930 ENOG4105DVT helicase DYQ48_20945 ENOG4105E2X shikimate dehydrogenase DYQ48_20965 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) DYQ48_20970 ENOG4105D52 delta-aminolevulinic acid dehydratase DYQ48_21010 ENOG4105CYM Glutathione S-transferase DYQ48_21030 ENOG4105QV4 Tryptophan halogenase DYQ48_21045 ENOG4108IUW ABC transporter DYQ48_21055 ENOG4105VZ8 Transcriptional regulator DYQ48_21085 ENOG4105DA5 (ABC) transporter DYQ48_21090 ENOG4105E3A (ABC) transporter DYQ48_21100 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) DYQ48_21135 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) DYQ48_21145 ENOG4107QYD Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) DYQ48_21160 ENOG4105CD5 CoA-binding domain protein DYQ48_21180 ENOG4105CJW magnesium transporter DYQ48_21190 ENOG4105CKD glutathione-regulated potassium-efflux system protein DYQ48_21195 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase DYQ48_21200 ENOG4105BZP glycoside hydrolase 15-related DYQ48_21220 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) DYQ48_21260 ENOG4105C2D reductase DYQ48_21285 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) DYQ48_21290 ENOG4105E9Q Acyl-transferase DYQ48_21300 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) DYQ48_21315 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) DYQ48_21340 ENOG4105DBS Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity) DYQ48_21345 ENOG4105C2M dna polymerase I DYQ48_21400 ENOG4105C4R Atp-dependent dna helicase DYQ48_21415 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) DYQ48_21425 ENOG4105JSC dimethylmenaquinone methyltransferase DYQ48_21435 ENOG4105KHM amidohydrolase 2 DYQ48_21440 ENOG4105W0E 50S ribosomal protein L33 DYQ48_21445 ENOG4105KDC 50s ribosomal protein l28 DYQ48_21455 ENOG4105ENT Efflux transporter rnd family, mfp subunit DYQ48_21480 ENOG4105D28 Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity) DYQ48_21485 ENOG4105DGI Alkaline phosphatase DYQ48_21510 ENOG4105CGK Exodeoxyribonuclease III DYQ48_21525 ENOG41061DF Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P (By similarity) DYQ48_21535 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) DYQ48_21545 ENOG4107QN1 sodium solute DYQ48_21550 ENOG41062QD Membrane DYQ48_21620 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr DYQ48_21625 ENOG4105ERH Fumarylacetoacetate hydrolase DYQ48_21630 ENOG4105DIA mandelate racemase muconate lactonizing DYQ48_21645 ENOG4105QJH Domain of unknown function (DUF718) DYQ48_21650 ENOG4105EDR glucose galactose transporter DYQ48_21655 ENOG4108K2P TRANSCRIPTIONal DYQ48_21670 ENOG4108UI1 Probably functions as a manganese efflux pump (By similarity) DYQ48_21675 ENOG4105BZU Histidine kinase DYQ48_21685 ENOG4105E2V Glycosyltransferase 36 DYQ48_21690 ENOG4105CT4 transporter DYQ48_21695 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family DYQ48_21720 ENOG4105F2I Transposase DYQ48_21740 ENOG4105MA0 exported protein DYQ48_21745 ENOG4105CFU surface antigen DYQ48_21755 ENOG4108HMW glycyl-tRNA synthetase, alpha subunit DYQ48_21760 ENOG4107QHF type ii secretion system protein e DYQ48_21775 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) DYQ48_21785 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) DYQ48_21790 ENOG4105X8U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity) DYQ48_21805 ENOG4105CFX Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) DYQ48_21820 ENOG4105DH7 May be involved in recombination (By similarity) DYQ48_21825 ENOG4105CB3 Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity) DYQ48_21835 ENOG4105C93 Xylose Isomerase DYQ48_21840 ENOG4105ETE Transcriptional regulator (LacI family DYQ48_21845 ENOG4105D0H Alpha-glucuronidase (EC 3.2.1.139) DYQ48_21855 ENOG4105CXK mandelate racemase muconate lactonizing DYQ48_21870 ENOG4105DEI Mannitol dehydrogenase DYQ48_21895 ENOG4105C5I Dehydrogenase DYQ48_21915 ENOG4105D9F endo-1,4-beta-xylanase (EC 3.2.1.8) DYQ48_21920 ENOG4105CNT hydrolase family 2 DYQ48_21925 ENOG4105D2H Uronic isomerase DYQ48_21945 ENOG4105CT4 transporter DYQ48_21950 ENOG4105DT9 hydrolase family 43 DYQ48_22010 ENOG4105E55 glycerol-3-phosphate acyltransferase DYQ48_22020 ENOG4105ETE Transcriptional regulator (LacI family DYQ48_22030 ENOG4105QV4 Tryptophan halogenase DYQ48_22035 ENOG4106EG9 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity) DYQ48_22040 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family DYQ48_22045 ENOG4108YXG UPF0502 protein DYQ48_22060 ENOG4105KNA -acetyltransferase DYQ48_22065 ENOG4105C4R Atp-dependent dna helicase DYQ48_22070 ENOG4107104 thymidine kinase DYQ48_22075 ENOG4105BZU Histidine kinase DYQ48_22080 ENOG4105DJ9 glucan biosynthesis protein DYQ48_22090 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) DYQ48_22120 ENOG4105DKK Benzoate DYQ48_22140 ENOG4105DSB aldose 1-epimerase DYQ48_22150 ENOG4105K5B UPF0225 protein DYQ48_22155 ENOG4105EJ9 Membrane DYQ48_22160 ENOG4105E0K tonB-dependent siderophore receptor DYQ48_22185 ENOG4105EUJ GTP cyclohydrolase i DYQ48_22195 ENOG4105ZQC membrane protein AaeX DYQ48_22200 ENOG4105Y49 secretion protein, HlyD family DYQ48_22210 ENOG4105DR8 Membrane DYQ48_22215 ENOG4105CSH Transporter DYQ48_22220 ENOG4105EJC lysr family transcriptional regulator DYQ48_22225 ENOG4105EMU Dehydrogenase DYQ48_22235 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) DYQ48_22265 ENOG4108Q9H CobQ/CobB/MinD/ParA nucleotide binding domain DYQ48_22340 ENOG4105D3G Pseudouridine synthase DYQ48_22365 ENOG4105CF7 AraC family transcriptional regulator DYQ48_22370 ENOG4105CYX Short-chain dehydrogenase reductase Sdr DYQ48_22375 ENOG4105VDM plasmid maintenance system antidote protein, xre family DYQ48_22380 ENOG41080ET plasmid maintenance system killer protein DYQ48_22390 ENOG4107QYX exodeoxyribonuclease v alpha DYQ48_22395 ENOG4107QKA exodeoxyribonuclease V beta DYQ48_22400 ENOG4105DSY exodeoxyribonuclease V, gamma DYQ48_22405 ENOG4105DHJ ABC, transporter DYQ48_22410 ENOG4105CY3 ABC transporter, permease DYQ48_22415 ENOG4107PE3 Mammalian cell entry related domain protein DYQ48_22430 ENOG410903C (LipO)protein DYQ48_22460 ENOG4108V06 Glutathione peroxidase DYQ48_22470 ENOG4107QSV RmuC domain protein DYQ48_22475 ENOG4108TGY Glutathione S-transferase DYQ48_22480 ENOG4105CUB amino acid DYQ48_22485 ENOG4105CWX Alpha-1,2-mannosidase DYQ48_22500 ENOG4105BZU Histidine kinase DYQ48_22505 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR DYQ48_22510 ENOG4105BZW Glycerate kinase DYQ48_22515 ENOG4105CSP Major Facilitator Superfamily DYQ48_22535 ENOG4107RNH Outer membrane receptor FepA DYQ48_22550 ENOG4105EAB amino acid AbC transporter DYQ48_22555 ENOG4105CDA abc transporter atp-binding protein DYQ48_22565 ENOG4105CH2 amidohydrolase DYQ48_22575 ENOG4105DEN Luciferase family DYQ48_22585 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) DYQ48_22605 ENOG4105DR4 Methyltransferase DYQ48_22615 ENOG4105DU1 integral membrane protein, terc DYQ48_22625 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase DYQ48_22650 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins DYQ48_22760 ENOG4106H6R UPF0380 protein DYQ48_22850 ENOG4108C33 Resolvase DYQ48_22895 ENOG4108NSC Pfam:DUF88 DYQ48_22955 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving DYQ48_22995 ENOG4108NSC Pfam:DUF88