locus-tag	class	description
NMB96_00035	COG0583	DNA-binding transcription factor activity
NMB96_00075	COG2003	Belongs to the UPF0758 family
NMB96_00145	COG0784	Response regulator, receiver
NMB96_00145	COG4191	Histidine kinase
NMB96_00160	COG1484	DNA-dependent DNA replication
NMB96_00165	COG4584	PFAM Integrase catalytic
NMB96_00230	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NMB96_00235	COG3273	potassium ion transport
NMB96_00235	COG0471	metal ion transport
NMB96_00265	COG1609	Transcriptional regulator
NMB96_00275	COG3250	beta-galactosidase activity
NMB96_00280	COG4948	Mandelate Racemase Muconate Lactonizing
NMB96_00290	COG2272	Belongs to the type-B carboxylesterase lipase family
NMB96_00295	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NMB96_00315	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NMB96_00320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NMB96_00325	COG2895	sulfate adenylyltransferase (ATP) activity
NMB96_00325	COG0529	Catalyzes the synthesis of activated sulfate
NMB96_00335	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NMB96_00340	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NMB96_00345	COG0175	sulfate reduction
NMB96_00365	COG2198	Histidine kinase
NMB96_00365	COG2205	protein histidine kinase activity
NMB96_00365	COG0784	Response regulator, receiver
NMB96_00395	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
NMB96_00400	COG3588	fructose-bisphosphate aldolase
NMB96_00405	COG0469	pyruvate kinase activity
NMB96_00435	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NMB96_00450	COG3047	cAMP biosynthetic process
NMB96_00460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NMB96_00460	COG3453	Protein conserved in bacteria
NMB96_00465	COG0725	ABC transporter, periplasmic molybdate-binding protein
NMB96_00470	COG4149	molybdate abc transporter
NMB96_00475	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
NMB96_00510	COG1376	ErfK ybiS ycfS ynhG family protein
NMB96_00525	COG1028	Short-chain dehydrogenase reductase Sdr
NMB96_00530	COG0583	DNA-binding transcription factor activity
NMB96_00535	COG4773	Receptor
NMB96_00540	COG0596	Alpha beta hydrolase
NMB96_00550	COG1301	dicarboxylic acid transport
NMB96_00580	COG0714	Associated with various cellular activities
NMB96_00610	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
NMB96_00635	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NMB96_00645	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NMB96_00660	COG1561	YicC-like family, N-terminal region
NMB96_00665	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NMB96_00670	COG0346	lactoylglutathione lyase activity
NMB96_00680	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NMB96_00695	COG0006	proline dipeptidase activity
NMB96_00705	COG0006	proline dipeptidase activity
NMB96_00730	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NMB96_00750	COG2912	Transglutaminase-like superfamily
NMB96_00755	COG1773	rubredoxin
NMB96_00760	COG0352	thiamine-phosphate diphosphorylase activity
NMB96_00770	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NMB96_00780	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
NMB96_00785	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NMB96_00815	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NMB96_00820	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NMB96_00835	COG1028	Short-chain dehydrogenase reductase Sdr
NMB96_00845	COG0671	phosphoesterase, PA-phosphatase related
NMB96_00850	COG3781	membrane
NMB96_00860	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NMB96_00865	COG0563	adenylate kinase activity
NMB96_00880	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
NMB96_00890	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NMB96_00910	COG3710	Transcriptional regulator
NMB96_00915	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NMB96_00930	COG4946	Tricorn protease homolog
NMB96_00930	COG1506	peptidase
NMB96_00930	COG0823	Involved in the tonB-independent uptake of proteins
NMB96_00935	COG0840	transmembrane signaling receptor activity
NMB96_00940	COG0405	Gamma-glutamyltransferase
NMB96_00945	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NMB96_00965	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NMB96_00970	COG0473	3-isopropylmalate dehydrogenase activity
NMB96_00975	COG2226	methyltransferase
NMB96_00980	COG0066	3-isopropylmalate dehydratase activity
NMB96_00985	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NMB96_01005	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NMB96_01010	COG1538	Outer membrane efflux protein
NMB96_01020	COG1519	Transferase
NMB96_01025	COG1560	Kdo2-lipid A biosynthetic process
NMB96_01050	COG0281	malic enzyme
NMB96_01050	COG0280	phosphate acetyltransferase
NMB96_01065	COG4191	Histidine kinase
NMB96_01085	COG0583	DNA-binding transcription factor activity
NMB96_01095	COG2197	response regulator
NMB96_01155	COG0642	Histidine kinase
NMB96_01170	COG2851	Citrate transporter
NMB96_01175	COG1028	Short-chain dehydrogenase reductase Sdr
NMB96_01180	COG1609	Transcriptional regulator
NMB96_01185	COG2211	Major facilitator Superfamily
NMB96_01225	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
NMB96_01290	COG0436	Aminotransferase
NMB96_01315	COG4773	Receptor
NMB96_01320	COG0726	polysaccharide deacetylase
NMB96_01325	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NMB96_01340	COG1228	amidohydrolase
NMB96_01370	COG1307	EDD domain protein, DegV family
NMB96_01380	COG0697	spore germination
NMB96_01390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NMB96_01400	COG3791	Glutathione-dependent formaldehyde-activating
NMB96_01415	COG3920	Histidine kinase
NMB96_01445	COG2205	protein histidine kinase activity
NMB96_01460	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
NMB96_01465	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NMB96_01480	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NMB96_01490	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NMB96_01500	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
NMB96_01520	COG0617	tRNA 3'-terminal CCA addition
NMB96_01535	COG1132	(ABC) transporter
NMB96_01545	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NMB96_01550	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NMB96_01555	COG1609	Transcriptional regulator
NMB96_01565	COG2188	Transcriptional regulator
NMB96_01580	COG3250	beta-galactosidase activity
NMB96_01605	COG3156	type II secretion system protein K
NMB96_01630	COG1459	type II secretion system
NMB96_01675	COG1028	Short-chain dehydrogenase reductase Sdr
NMB96_01680	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NMB96_01685	COG4191	Histidine kinase
NMB96_01690	COG0784	Response regulator, receiver
NMB96_01695	COG4251	negative regulation of phosphorylation
NMB96_01700	COG2823	Periplasmic or secreted lipoprotein
NMB96_01705	COG0673	inositol 2-dehydrogenase activity
NMB96_01710	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
NMB96_01745	COG1051	belongs to the nudix hydrolase family
NMB96_01745	COG1056	cytidyltransferase-related domain
NMB96_01760	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NMB96_01765	COG0321	lipoyl(octanoyl) transferase activity
NMB96_01770	COG2921	Belongs to the UPF0250 family
NMB96_01780	COG1686	Belongs to the peptidase S11 family
NMB96_01785	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NMB96_01790	COG2951	lytic endotransglycosylase activity
NMB96_01825	COG0772	Belongs to the SEDS family
NMB96_01835	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
NMB96_01840	COG1792	Involved in formation and maintenance of cell shape
NMB96_01845	COG1077	Cell shape determining protein MreB Mrl
NMB96_01850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NMB96_01855	COG3284	Transcriptional regulator
NMB96_01885	COG0028	Belongs to the TPP enzyme family
NMB96_01885	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
NMB96_01895	COG1213	nucleotidyl transferase
NMB96_01900	COG0367	asparagine synthase
NMB96_01905	COG1012	belongs to the aldehyde dehydrogenase family
NMB96_01910	COG0730	response to heat
NMB96_01930	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
NMB96_01965	COG0308	aminopeptidase N
NMB96_01970	COG3300	MHYT domain
NMB96_01970	COG5001	Diguanylate cyclase
NMB96_01975	COG2226	methyltransferase
NMB96_02000	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NMB96_02005	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NMB96_02010	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NMB96_02025	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NMB96_02035	COG2832	Protein of unknown function (DUF454)
NMB96_02045	COG0436	Aminotransferase
NMB96_02055	COG1505	serine-type exopeptidase activity
NMB96_02080	COG0181	hydroxymethylbilane synthase activity
NMB96_02090	COG3275	phosphorelay sensor kinase activity
NMB96_02120	COG0659	secondary active sulfate transmembrane transporter activity
NMB96_02125	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NMB96_02125	COG5297	Belongs to the glycosyl hydrolase family 6
NMB96_02130	COG0840	transmembrane signaling receptor activity
NMB96_02175	COG3507	Belongs to the glycosyl hydrolase 43 family
NMB96_02190	COG1113	amino acid transport
NMB96_02195	COG4305	rare lipoprotein A
NMB96_02210	COG0697	spore germination
NMB96_02245	COG0823	Involved in the tonB-independent uptake of proteins
NMB96_02245	COG1506	peptidase
NMB96_02280	COG0435	Glutathione S-transferase
NMB96_02325	COG0823	Involved in the tonB-independent uptake of proteins
NMB96_02325	COG1506	peptidase
NMB96_02330	COG4206	TonB-dependent receptor
NMB96_02500	COG1802	Transcriptional regulator
NMB96_02535	COG3052	prosthetic group binding
NMB96_02560	COG2353	YceI-like domain
NMB96_02585	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NMB96_02620	COG3712	iron ion homeostasis
NMB96_02645	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NMB96_02670	COG2356	endonuclease I
NMB96_02675	COG1324	tolerance protein
NMB96_02695	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NMB96_02700	COG0511	ligase activity, forming carbon-carbon bonds
NMB96_02705	COG0439	Biotin carboxylase
NMB96_02720	COG2264	protein methyltransferase activity
NMB96_02740	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
NMB96_02755	COG0138	bifunctional purine biosynthesis protein purh
NMB96_02760	COG0151	Belongs to the GarS family
NMB96_02765	COG1289	transmembrane transporter activity
NMB96_02770	COG2814	Major facilitator Superfamily
NMB96_02795	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
NMB96_02810	COG0316	Belongs to the HesB IscA family
NMB96_02875	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
NMB96_02890	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NMB96_02900	COG0134	indole-3-glycerol-phosphate synthase activity
NMB96_02905	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NMB96_03010	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NMB96_03110	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NMB96_03115	COG0625	glutathione transferase activity
NMB96_03125	COG0583	DNA-binding transcription factor activity
NMB96_03130	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
NMB96_03145	COG0655	NAD(P)H dehydrogenase (quinone) activity
NMB96_03150	COG0583	DNA-binding transcription factor activity
NMB96_03155	COG0583	DNA-binding transcription factor activity
NMB96_03175	COG1597	lipid kinase activity
NMB96_03195	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
NMB96_03220	COG3179	chitinase
NMB96_03240	COG2111	Na H antiporter
NMB96_03240	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NMB96_03245	COG1006	Multisubunit Na H antiporter MnhC subunit
NMB96_03250	COG0651	ATP synthesis coupled electron transport
NMB96_03260	COG2212	antiporter activity
NMB96_03265	COG1320	monovalent cation:proton antiporter activity
NMB96_03285	COG2852	Protein conserved in bacteria
NMB96_03305	COG3104	oligopeptide transport
NMB96_03320	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NMB96_03335	COG0508	dehydrogenase complex catalyzes the overall conversion of
NMB96_03340	COG0513	Belongs to the DEAD box helicase family
NMB96_03350	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NMB96_03395	COG1028	Short-chain dehydrogenase reductase Sdr
NMB96_03400	COG0702	epimerase
NMB96_03425	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NMB96_03430	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NMB96_03435	COG0297	glycogen (starch) synthase activity
NMB96_03445	COG1649	PFAM Uncharacterised BCR, COG1649
NMB96_03450	COG2354	Protein conserved in bacteria
NMB96_03455	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NMB96_03460	COG1368	sulfuric ester hydrolase activity
NMB96_03470	COG1511	domain protein
NMB96_03470	COG3264	Mechanosensitive ion channel
NMB96_03490	COG3590	peptidase
NMB96_03500	COG0582	viral genome integration into host DNA
NMB96_03505	COG0582	viral genome integration into host DNA
NMB96_03520	COG1040	competence protein
NMB96_03525	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NMB96_03530	COG0156	8-amino-7-oxononanoate synthase activity
NMB96_03575	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NMB96_03595	COG0657	acetylesterase activity
NMB96_03605	COG1414	Transcriptional regulator
NMB96_03615	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NMB96_03620	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NMB96_03625	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NMB96_03630	COG3485	protocatechuate 3,4-dioxygenase
NMB96_03635	COG3485	protocatechuate 3,4-dioxygenase
NMB96_03640	COG0183	Belongs to the thiolase family
NMB96_03645	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NMB96_03650	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NMB96_03685	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NMB96_03690	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NMB96_03740	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NMB96_03750	COG0129	dihydroxy-acid dehydratase activity
NMB96_03775	COG0270	DNA (cytosine-5-)-methyltransferase activity
NMB96_03780	COG0270	DNA (cytosine-5-)-methyltransferase activity
NMB96_03855	COG0840	transmembrane signaling receptor activity
NMB96_03865	COG1733	regulation of RNA biosynthetic process
NMB96_03870	COG0702	epimerase
NMB96_03895	COG0583	DNA-binding transcription factor activity
NMB96_03900	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NMB96_03920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NMB96_03925	COG2205	protein histidine kinase activity
NMB96_03930	COG0745	RESPONSE REGULATOR receiver
NMB96_03935	COG2223	nitrite transmembrane transporter activity
NMB96_03955	COG1902	pentaerythritol trinitrate reductase activity
NMB96_03960	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NMB96_03990	COG2814	Major facilitator Superfamily
NMB96_03995	COG0583	DNA-binding transcription factor activity
NMB96_04010	COG0084	hydrolase, TatD family'
NMB96_04030	COG2252	PERMEase
NMB96_04040	COG1957	nucleoside hydrolase
NMB96_04155	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NMB96_04175	COG2072	flavoprotein involved in K transport
NMB96_04180	COG2351	hydroxyisourate hydrolase activity
NMB96_04185	COG4807	Protein conserved in bacteria
NMB96_04190	COG0840	transmembrane signaling receptor activity
NMB96_04195	COG1643	Atp-dependent helicase
NMB96_04205	COG1187	pseudouridine synthase activity
NMB96_04220	COG2130	NADP-dependent
NMB96_04225	COG0656	L-ascorbic acid biosynthetic process
NMB96_04250	COG1764	response to oxidative stress
NMB96_04255	COG1846	Transcriptional regulator
NMB96_04265	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
NMB96_04275	COG0697	spore germination
NMB96_04290	COG0523	cobalamin synthesis protein
NMB96_04345	COG1960	acyl-CoA dehydrogenase activity
NMB96_04350	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NMB96_04355	COG4770	biotin carboxylase activity
NMB96_04385	COG2224	Isocitrate lyase
NMB96_04390	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NMB96_04395	COG0583	DNA-binding transcription factor activity
NMB96_04400	COG0475	glutathione-regulated potassium exporter activity
NMB96_04430	COG0339	signal peptide processing
NMB96_04435	COG1446	asparaginase
NMB96_04480	COG1181	Belongs to the D-alanine--D-alanine ligase family
NMB96_04490	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NMB96_04505	COG0318	PFAM AMP-dependent synthetase and ligase
NMB96_04510	COG0727	PFAM Uncharacterised protein family (UPF0153)
NMB96_04515	COG0596	Alpha beta hydrolase
NMB96_04520	COG3177	Filamentation induced by cAMP protein fic
NMB96_04525	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NMB96_04540	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NMB96_04570	COG4191	Histidine kinase
NMB96_04575	COG0028	Belongs to the TPP enzyme family
NMB96_04585	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NMB96_04595	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NMB96_04630	COG0183	Belongs to the thiolase family
NMB96_04640	COG2032	superoxide dismutase activity
NMB96_04645	COG2032	superoxide dismutase activity
NMB96_04650	COG2204	response regulator
NMB96_04655	COG3852	Histidine kinase
NMB96_04660	COG0004	ammonium transporteR
NMB96_04665	COG0347	Belongs to the P(II) protein family
NMB96_04670	COG0174	glutamine synthetase
NMB96_04685	COG1881	PFAM PEBP family protein
NMB96_04715	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NMB96_04725	COG2062	phosphohistidine phosphatase, SixA
NMB96_04730	COG0489	protein tyrosine kinase activity
NMB96_04750	COG1396	sequence-specific DNA binding
NMB96_04755	COG3550	peptidyl-serine autophosphorylation
NMB96_04765	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NMB96_04780	COG0517	IMP dehydrogenase activity
NMB96_04780	COG1125	glycine betaine transport
NMB96_04795	COG1119	ATPase activity
NMB96_04800	COG1752	Esterase of the alpha-beta hydrolase superfamily
NMB96_04810	COG1522	sequence-specific DNA binding
NMB96_04815	COG3186	Phenylalanine-4-hydroxylase
NMB96_04840	COG2755	lipolytic protein G-D-S-L family
NMB96_04855	COG1028	Short-chain dehydrogenase reductase Sdr
NMB96_04860	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NMB96_04865	COG1609	Transcriptional regulator
NMB96_04870	COG3507	Belongs to the glycosyl hydrolase 43 family
NMB96_04885	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
NMB96_04895	COG0657	acetylesterase activity
NMB96_04895	COG2755	lipolytic protein G-D-S-L family
NMB96_04905	COG2755	lipolytic protein G-D-S-L family
NMB96_04950	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NMB96_04955	COG0366	Alpha amylase catalytic
NMB96_04960	COG0366	Alpha amylase catalytic
NMB96_05095	COG4771	TonB-dependent receptor
NMB96_05110	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NMB96_05115	COG3710	Transcriptional regulator
NMB96_05130	COG2197	response regulator
NMB96_05135	COG4585	Histidine kinase
NMB96_05140	COG1755	Isoprenylcysteine carboxyl methyltransferase
NMB96_05195	COG1028	Short-chain dehydrogenase reductase Sdr
NMB96_05200	COG1012	belongs to the aldehyde dehydrogenase family
NMB96_05215	COG0662	Cupin 2, conserved barrel domain protein
NMB96_05225	COG4772	TonB-dependent receptor
NMB96_05235	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
NMB96_05285	COG0714	Associated with various cellular activities
NMB96_05330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NMB96_05340	COG0657	acetylesterase activity
NMB96_05380	COG3237	CsbD-like
NMB96_05390	COG3275	phosphorelay sensor kinase activity
NMB96_05395	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NMB96_05505	COG1733	regulation of RNA biosynthetic process
NMB96_05515	COG1028	Short-chain dehydrogenase reductase Sdr
NMB96_05520	COG0583	DNA-binding transcription factor activity
NMB96_05545	COG1272	protein, Hemolysin III
NMB96_05550	COG1205	dead DEAH box helicase
NMB96_05550	COG1111	helicase
NMB96_05615	COG1484	DNA-dependent DNA replication
NMB96_05620	COG4584	PFAM Integrase catalytic
NMB96_05720	COG3459	Glycosyltransferase 36 associated
NMB96_05735	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NMB96_05740	COG1741	Belongs to the pirin family
NMB96_05780	COG0067	glutamate synthase
NMB96_05780	COG0069	glutamate synthase activity
NMB96_05780	COG0070	glutamate synthase
NMB96_05785	COG0493	'glutamate synthase
NMB96_05795	COG1064	alcohol dehydrogenase
NMB96_05800	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NMB96_05805	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NMB96_05810	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NMB96_05815	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NMB96_05830	COG2234	aminopeptidase activity
NMB96_05840	COG4942	peptidase
NMB96_05845	COG0793	Belongs to the peptidase S41A family
NMB96_05850	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NMB96_05880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NMB96_05890	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
NMB96_05925	COG0501	Belongs to the peptidase M48B family
NMB96_05935	COG0187	DNA topoisomerase II activity
NMB96_05965	COG0706	membrane insertase activity
NMB96_05990	COG0584	glycerophosphoryl diester phosphodiesterase
NMB96_06000	COG0861	Integral membrane protein TerC family
NMB96_06005	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NMB96_06050	COG2271	Major facilitator Superfamily
NMB96_06055	COG1929	Belongs to the glycerate kinase type-1 family
NMB96_06060	COG3835	regulator
NMB96_06065	COG2199	diguanylate cyclase activity
NMB96_06065	COG2203	Gaf domain
NMB96_06075	COG3537	Alpha-1,2-mannosidase
NMB96_06080	COG0531	amino acid
NMB96_06085	COG0625	glutathione transferase activity
NMB96_06090	COG1322	Protein conserved in bacteria
NMB96_06100	COG0386	Belongs to the glutathione peroxidase family
NMB96_06120	COG2853	Lipoprotein
NMB96_06135	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NMB96_06140	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NMB96_06145	COG1127	ABC transporter
NMB96_06180	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
NMB96_06185	COG1074	ATP-dependent DNA helicase activity
NMB96_06190	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NMB96_06275	COG3039	Transposase
NMB96_06280	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NMB96_06310	COG3039	Transposase
NMB96_06325	COG3549	Plasmid maintenance system killer
NMB96_06475	COG1487	ribonuclease activity
NMB96_06480	COG4691	Plasmid stability protein
NMB96_06500	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NMB96_06515	COG4221	oxidoreductase activity
NMB96_06525	COG0477	Major facilitator Superfamily
NMB96_06530	COG1289	transmembrane transporter activity
NMB96_06540	COG1566	PFAM secretion protein HlyD family protein
NMB96_06555	COG0302	gtp cyclohydrolase
NMB96_06580	COG0730	response to heat
NMB96_06595	COG0676	glucose-6-phosphate 1-epimerase activity
NMB96_06615	COG3135	benzoate transporter
NMB96_06645	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NMB96_06655	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
NMB96_06665	COG1435	thymidine kinase activity
NMB96_06670	COG0210	DNA helicase
NMB96_06690	COG3132	Protein of unknown function, DUF480
NMB96_06695	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
NMB96_06700	COG0284	orotidine-5'-phosphate decarboxylase activity
NMB96_06730	COG2937	Belongs to the GPAT DAPAT family
NMB96_06795	COG2211	Major facilitator Superfamily
NMB96_06810	COG3693	PFAM glycoside hydrolase, family 10
NMB96_06815	COG1904	glucuronate isomerase
NMB96_06820	COG3250	beta-galactosidase activity
NMB96_06830	COG3386	PFAM SMP-30 Gluconolaconase
NMB96_06845	COG1620	l-lactate permease
NMB96_06850	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NMB96_06880	COG0246	Mannitol dehydrogenase
NMB96_06885	COG1472	Belongs to the glycosyl hydrolase 3 family
NMB96_06895	COG4948	Mandelate Racemase Muconate Lactonizing
NMB96_06905	COG3661	Belongs to the glycosyl hydrolase 67 family
NMB96_06915	COG2115	Belongs to the xylose isomerase family
NMB96_06920	COG0037	tRNA processing
NMB96_06925	COG2974	May be involved in recombination
NMB96_06940	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NMB96_06950	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NMB96_06955	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NMB96_06960	COG0805	protein transport
NMB96_06970	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NMB96_06970	COG0519	Catalyzes the synthesis of GMP from XMP
NMB96_06980	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NMB96_06995	COG0457	Tetratricopeptide repeat
NMB96_07000	COG4771	TonB-dependent receptor
NMB96_07005	COG0729	surface antigen
NMB96_07010	COG2911	Protein conserved in bacteria
NMB96_07030	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NMB96_07035	COG3265	gluconokinase activity
NMB96_07040	COG2211	Major facilitator Superfamily
NMB96_07045	COG3459	Glycosyltransferase 36 associated
NMB96_07050	COG2205	protein histidine kinase activity
NMB96_07055	COG1971	Probably functions as a manganese efflux pump
NMB96_07070	COG1414	Transcriptional regulator
NMB96_07075	COG0738	Major facilitator superfamily
NMB96_07080	COG3254	rhamnose metabolic process
NMB96_07085	COG4948	Mandelate Racemase Muconate Lactonizing
NMB96_07090	COG0179	Fumarylacetoacetate (FAA) hydrolase
NMB96_07095	COG1028	Short-chain dehydrogenase reductase Sdr
NMB96_07145	COG3162	membrane
NMB96_07150	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NMB96_07170	COG1940	carbohydrate kinase activity
NMB96_07185	COG0708	Exodeoxyribonuclease III
NMB96_07200	COG2091	lysine biosynthetic process via aminoadipic acid
NMB96_07260	COG3540	Alkaline phosphatase
NMB96_07285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NMB96_07310	COG2159	amidohydrolase
NMB96_07320	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NMB96_07330	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NMB96_07345	COG0210	DNA helicase
NMB96_07365	COG3621	Patatin-like phospholipase
NMB96_07465	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NMB96_07510	COG1028	Short-chain dehydrogenase reductase Sdr
NMB96_07525	COG0463	Glycosyl transferase, family 2
NMB96_07535	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NMB96_07540	COG3100	YcgL domain-containing protein
NMB96_07550	COG3387	PFAM Glycoside hydrolase 15-related
NMB96_07555	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NMB96_07565	COG2239	Acts as a magnesium transporter
NMB96_07570	COG1629	transport
NMB96_07570	COG4771	TonB-dependent receptor
NMB96_07585	COG1042	CoA-binding domain protein
NMB96_07585	COG0045	succinate-CoA ligase (ADP-forming) activity
NMB96_07585	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NMB96_07595	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NMB96_07600	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NMB96_07615	COG1607	acyl-coa hydrolase
NMB96_07630	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NMB96_07640	COG0842	Transport permease protein
NMB96_07645	COG1131	(ABC) transporter
NMB96_07690	COG1476	TRANSCRIPTIONal
NMB96_07695	COG0596	Alpha beta hydrolase
NMB96_07700	COG4555	ABC transporter
NMB96_07735	COG0625	glutathione transferase activity
NMB96_07775	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NMB96_07800	COG1199	ATP-dependent helicase activity
NMB96_07845	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NMB96_07875	COG3228	Belongs to the MtfA family
NMB96_07885	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
NMB96_07885	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
NMB96_07890	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NMB96_07905	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NMB96_07945	COG3237	CsbD-like
NMB96_07950	COG0180	Tryptophanyl-tRNA synthetase
NMB96_07975	COG0697	spore germination
NMB96_08000	COG1136	(ABC) transporter
NMB96_08005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NMB96_08015	COG2197	response regulator
NMB96_08035	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NMB96_08040	COG1011	Hydrolase
NMB96_08065	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NMB96_08085	COG0642	Histidine kinase
NMB96_08095	COG1090	epimerase
NMB96_08150	COG4943	cyclic-guanylate-specific phosphodiesterase activity
NMB96_08165	COG0606	chelatase, subunit chli
NMB96_08205	COG1166	arginine decarboxylase activity
NMB96_08210	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NMB96_08220	COG2755	lipolytic protein G-D-S-L family
NMB96_08220	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NMB96_08225	COG4221	oxidoreductase activity
NMB96_08235	COG0018	arginyl-trna synthetase
NMB96_08245	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NMB96_08250	COG0756	dUTP diphosphatase activity
NMB96_08270	COG0463	Glycosyl transferase, family 2
NMB96_08285	COG1475	DNA binding
NMB96_08290	COG1192	Involved in chromosome partitioning
NMB96_08305	COG0708	Exodeoxyribonuclease III
NMB96_08310	COG2211	Major facilitator Superfamily
NMB96_08325	COG0739	heme binding
NMB96_08370	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NMB96_08385	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
NMB96_08415	COG0109	protoheme IX farnesyltransferase activity
NMB96_08430	COG0358	DNA primase activity
NMB96_08435	COG1295	ribonuclease BN
NMB96_08440	COG1610	YqeY-like protein
NMB96_08455	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NMB96_08470	COG2133	pyrroloquinoline quinone binding
NMB96_08475	COG4682	membrane
NMB96_08490	COG0531	amino acid
NMB96_08500	COG4948	Mandelate Racemase Muconate Lactonizing
NMB96_08510	COG3023	N-Acetylmuramoyl-L-alanine amidase
NMB96_08515	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
NMB96_08550	COG5383	Protein conserved in bacteria
NMB96_08560	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NMB96_08565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NMB96_08570	COG1473	amidohydrolase
NMB96_08575	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NMB96_08575	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NMB96_08595	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
NMB96_08630	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NMB96_08635	COG3118	belongs to the thioredoxin family
NMB96_08645	COG2884	Cell division ATP-binding protein ftsE
NMB96_08650	COG2177	Part of the ABC transporter FtsEX involved in
NMB96_08655	COG2201	protein-glutamate methylesterase activity
NMB96_08660	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NMB96_08665	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NMB96_08670	COG2860	membrane
NMB96_08675	COG1252	NADH dehydrogenase
NMB96_08690	COG0625	glutathione transferase activity
NMB96_08695	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NMB96_08710	COG0534	Mate efflux family protein
NMB96_08715	COG0616	signal peptide processing
NMB96_08725	COG1028	Short-chain dehydrogenase reductase Sdr
NMB96_08740	COG0009	L-threonylcarbamoyladenylate synthase
NMB96_08745	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NMB96_08745	COG1754	DNA topoisomerase type I activity
NMB96_08765	COG0758	DNA mediated transformation
NMB96_08770	COG1652	LysM domain
NMB96_08775	COG0242	peptide deformylase activity
NMB96_08780	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NMB96_08785	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NMB96_08785	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NMB96_08820	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NMB96_08830	COG1560	Kdo2-lipid A biosynthetic process
NMB96_08835	COG1490	D-aminoacyl-tRNA deacylase activity
NMB96_08840	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NMB96_08855	COG0582	viral genome integration into host DNA
NMB96_08875	COG4584	PFAM Integrase catalytic
NMB96_08880	COG1484	DNA-dependent DNA replication
NMB96_08950	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NMB96_08970	COG4584	PFAM Integrase catalytic
NMB96_08975	COG1484	DNA-dependent DNA replication
NMB96_08995	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NMB96_09015	COG0840	transmembrane signaling receptor activity
NMB96_09035	COG0251	oxidation-reduction process
NMB96_09050	COG1131	(ABC) transporter
NMB96_09090	COG2814	Major facilitator Superfamily
NMB96_09095	COG0583	DNA-binding transcription factor activity
NMB96_09120	COG1063	alcohol dehydrogenase
NMB96_09135	COG1271	oxidase subunit
NMB96_09140	COG1294	oxidase, subunit
NMB96_09155	COG1028	Short-chain dehydrogenase reductase Sdr
NMB96_09160	COG2204	response regulator
NMB96_09180	COG3546	catalase activity
NMB96_09185	COG3685	Protein conserved in bacteria
NMB96_09210	COG2972	Histidine kinase
NMB96_09225	COG0531	amino acid
NMB96_09240	COG3590	peptidase
NMB96_09250	COG0667	Aldo Keto reductase
NMB96_09260	COG0583	DNA-binding transcription factor activity
NMB96_09270	COG3384	dioxygenase
NMB96_09280	COG1573	uracil-dna glycosylase
NMB96_09285	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
NMB96_09295	COG0025	NhaP-type Na H and K H
NMB96_09300	COG1131	(ABC) transporter
NMB96_09305	COG0842	Transport permease protein
NMB96_09365	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NMB96_09370	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NMB96_09390	COG0784	Response regulator, receiver
NMB96_09390	COG2205	protein histidine kinase activity
NMB96_09390	COG2198	Histidine kinase
NMB96_09390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NMB96_09410	COG2813	Specifically methylates the guanine in position
NMB96_09415	COG1187	pseudouridine synthase activity
NMB96_09435	COG1666	GTP binding
NMB96_09440	COG0697	spore germination
NMB96_09445	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NMB96_09450	COG2011	ABC-type metal ion transport system permease component
NMB96_09480	COG0508	dehydrogenase complex catalyzes the overall conversion of
NMB96_09490	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NMB96_09505	COG0356	it plays a direct role in the translocation of protons across the membrane
NMB96_09515	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NMB96_09555	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NMB96_09565	COG4191	Histidine kinase
NMB96_09575	COG0577	efflux transmembrane transporter activity
NMB96_09580	COG0577	efflux transmembrane transporter activity
NMB96_09580	COG1136	(ABC) transporter
NMB96_09585	COG1136	(ABC) transporter
NMB96_09590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NMB96_09595	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NMB96_09600	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NMB96_09650	COG0339	signal peptide processing
NMB96_09665	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NMB96_09675	COG0546	phosphoglycolate phosphatase activity
NMB96_09685	COG2819	hydrolase of the alpha beta superfamily
NMB96_09695	COG1956	GAF domain-containing protein
NMB96_09700	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NMB96_09710	COG0720	synthase
NMB96_09715	COG4771	TonB-dependent receptor
NMB96_09725	COG0513	Belongs to the DEAD box helicase family
NMB96_09735	COG0625	glutathione transferase activity
NMB96_09765	COG0626	cystathionine gamma-synthase activity
NMB96_09825	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NMB96_09835	COG0277	FAD linked oxidase domain protein
NMB96_09840	COG0546	phosphoglycolate phosphatase activity
NMB96_09840	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NMB96_09855	COG2086	electron transfer activity
NMB96_09880	COG0662	Cupin 2, conserved barrel domain protein
NMB96_09880	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
NMB96_09885	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NMB96_09925	COG3218	ABC-type transport auxiliary lipoprotein component
NMB96_09925	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NMB96_09930	COG1127	ABC transporter
NMB96_09935	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NMB96_09950	COG0442	prolyl-tRNA aminoacylation
NMB96_09960	COG1183	phosphatidylcholine synthase activity
NMB96_09985	COG0525	valine-tRNA ligase activity
NMB96_10010	COG0795	lipopolysaccharide-transporting ATPase activity
NMB96_10025	COG4974	Belongs to the 'phage' integrase family
NMB96_10030	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NMB96_10035	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NMB96_10035	COG0047	phosphoribosylformylglycinamidine synthase activity
NMB96_10045	COG1404	Belongs to the peptidase S8 family
NMB96_10055	COG5295	Hep Hag repeat protein
NMB96_10060	COG1404	Belongs to the peptidase S8 family
NMB96_10065	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NMB96_10070	COG1459	type II secretion system
NMB96_10075	COG2165	general secretion pathway protein
NMB96_10080	COG4970	Tfp pilus assembly protein FimT
NMB96_10085	COG2165	general secretion pathway protein
NMB96_10090	COG4795	General secretion pathway protein
NMB96_10095	COG3156	type II secretion system protein K
NMB96_10100	COG3166	PFAM Fimbrial assembly family protein
NMB96_10115	COG1450	Type ii and iii secretion system protein
NMB96_10130	COG2188	Transcriptional regulator
NMB96_10175	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NMB96_10190	COG0242	peptide deformylase activity
NMB96_10195	COG0488	(ABC) transporter
NMB96_10205	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NMB96_10220	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NMB96_10220	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NMB96_10260	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NMB96_10275	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NMB96_10280	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NMB96_10290	COG2205	protein histidine kinase activity
NMB96_10295	COG0745	RESPONSE REGULATOR receiver
NMB96_10310	COG0277	FAD linked oxidase domain protein
NMB96_10315	COG1988	membrane-bound metal-dependent
NMB96_10320	COG0792	nuclease activity
NMB96_10360	COG0275	rRNA processing
NMB96_10365	COG3116	cell division
NMB96_10375	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NMB96_10380	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NMB96_10395	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NMB96_10400	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NMB96_10405	COG1181	Belongs to the D-alanine--D-alanine ligase family
NMB96_10410	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NMB96_10420	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NMB96_10435	COG0739	heme binding
NMB96_10440	COG0653	protein targeting
NMB96_10450	COG0494	nUDIX hydrolase
NMB96_10465	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NMB96_10475	COG3321	synthase
NMB96_10475	COG1028	Short-chain dehydrogenase reductase Sdr
NMB96_10475	COG0604	alcohol dehydrogenase
NMB96_10520	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NMB96_10555	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NMB96_10565	COG4106	trans-aconitate 2-methyltransferase activity
NMB96_10570	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NMB96_10580	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NMB96_10585	COG0667	Aldo Keto reductase
NMB96_10595	COG4771	TonB-dependent receptor
NMB96_10615	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NMB96_10620	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
NMB96_10630	COG2175	clavaminate synthase activity
NMB96_10640	COG4181	ATPase activity
NMB96_10655	COG0642	Histidine kinase
NMB96_10665	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NMB96_10690	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NMB96_10710	COG1116	anion transmembrane transporter activity
NMB96_10715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NMB96_10725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NMB96_10730	COG0431	NADPH-dependent FMN reductase
NMB96_10735	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NMB96_10740	COG2967	ApaG domain
NMB96_10745	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NMB96_10750	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NMB96_10765	COG0123	including yeast histone deacetylase and acetoin utilization protein
NMB96_10770	COG2096	Adenosyltransferase
NMB96_10780	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NMB96_10785	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NMB96_10815	COG3384	dioxygenase
NMB96_10820	COG0583	DNA-binding transcription factor activity
NMB96_10825	COG0318	PFAM AMP-dependent synthetase and ligase
NMB96_10835	COG1024	Enoyl-CoA hydratase
NMB96_10855	COG3386	PFAM SMP-30 Gluconolaconase
NMB96_10880	COG0697	spore germination
NMB96_10885	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NMB96_10910	COG2197	response regulator
NMB96_10920	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NMB96_10930	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NMB96_10935	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NMB96_10940	COG0583	DNA-binding transcription factor activity
NMB96_10945	COG3634	alkyl hydroperoxide reductase activity
NMB96_10955	COG2890	protein-(glutamine-N5) methyltransferase activity
NMB96_10980	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NMB96_10980	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NMB96_11030	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NMB96_11035	COG1404	Belongs to the peptidase S8 family
NMB96_11045	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NMB96_11065	COG1295	ribonuclease BN
NMB96_11070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NMB96_11090	COG0521	Mo-molybdopterin cofactor biosynthetic process
NMB96_11110	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NMB96_11120	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
NMB96_11135	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NMB96_11140	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NMB96_11145	COG0193	aminoacyl-tRNA hydrolase activity
NMB96_11150	COG0012	GTP binding
NMB96_11185	COG0250	Participates in transcription elongation, termination and antitermination
NMB96_11190	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NMB96_11195	COG0081	regulation of translation
NMB96_11200	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NMB96_11205	COG0222	ribosome binding
NMB96_11215	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NMB96_11220	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NMB96_11235	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NMB96_11240	COG0051	transcription antitermination factor activity, RNA binding
NMB96_11260	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NMB96_11270	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NMB96_11285	COG0255	Belongs to the universal ribosomal protein uL29 family
NMB96_11290	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NMB96_11300	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NMB96_11345	COG0201	protein transport
NMB96_11370	COG0203	ribosomal protein L17
NMB96_11380	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
NMB96_11390	COG0154	amidase activity
NMB96_11400	COG1217	gtp-binding protein TYPA
NMB96_11405	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NMB96_11415	COG0625	glutathione transferase activity
NMB96_11435	COG1902	pentaerythritol trinitrate reductase activity
NMB96_11435	COG0446	pyridine nucleotide-disulphide oxidoreductase
NMB96_11440	COG0604	alcohol dehydrogenase
NMB96_11445	COG2885	chlorophyll binding
NMB96_11465	COG0156	8-amino-7-oxononanoate synthase activity
NMB96_11470	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
NMB96_11475	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
NMB96_11480	COG4208	sulfate ABC transporter
NMB96_11485	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NMB96_11495	COG1063	alcohol dehydrogenase
NMB96_11515	COG0406	alpha-ribazole phosphatase activity
NMB96_11525	COG0285	dihydrofolate synthase activity
NMB96_11545	COG2833	Protein of unknown function (DUF455)
NMB96_11550	COG3291	Pkd domain containing protein
NMB96_11560	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NMB96_11565	COG0671	phosphoesterase, PA-phosphatase related
NMB96_11570	COG0438	transferase activity, transferring glycosyl groups
NMB96_11580	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NMB96_11590	COG0745	RESPONSE REGULATOR receiver
NMB96_11595	COG4783	chaperone-mediated protein folding
NMB96_11610	COG0473	3-isopropylmalate dehydrogenase activity
NMB96_11665	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NMB96_11695	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NMB96_11705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NMB96_11725	COG0631	protein serine/threonine phosphatase activity
NMB96_11740	COG0859	PFAM glycosyl transferase family 9
NMB96_11755	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NMB96_11760	COG0315	cyclic pyranopterin monophosphate synthase activity
NMB96_11765	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NMB96_11770	COG0314	molybdopterin synthase activity
NMB96_11790	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NMB96_11800	COG0537	adenosine 5'-monophosphoramidase activity
NMB96_11820	COG0714	Associated with various cellular activities
NMB96_11840	COG1399	metal-binding, possibly nucleic acid-binding protein
NMB96_11845	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NMB96_11850	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NMB96_11855	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NMB96_11875	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NMB96_11880	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NMB96_11900	COG4115	mRNA cleavage
NMB96_11905	COG2161	toxin-antitoxin pair type II binding
NMB96_11915	COG3829	transcription factor binding
NMB96_11930	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NMB96_11935	COG3609	addiction module antidote protein, CC2985 family
NMB96_11960	COG2373	Large extracellular alpha-helical protein
NMB96_11990	COG0577	efflux transmembrane transporter activity
NMB96_11990	COG1136	(ABC) transporter
NMB96_12000	COG2204	response regulator
NMB96_12020	COG0678	peroxiredoxin activity
NMB96_12040	COG0330	HflC and HflK could
NMB96_12045	COG0330	HflC and HflK could
NMB96_12115	COG0732	type I restriction modification DNA specificity domain
NMB96_12170	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NMB96_12180	COG1028	Short-chain dehydrogenase reductase Sdr
NMB96_12190	COG3537	Alpha-1,2-mannosidase
NMB96_12250	COG2271	Major facilitator Superfamily
NMB96_12275	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NMB96_12280	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
NMB96_12285	COG2080	2 iron, 2 sulfur cluster binding
NMB96_12340	COG0587	DNA-directed DNA polymerase activity
NMB96_12350	COG1297	OPT oligopeptide transporter protein
NMB96_12370	COG1506	peptidase
NMB96_12370	COG0823	Involved in the tonB-independent uptake of proteins
NMB96_12385	COG1917	Cupin 2, conserved barrel domain protein
NMB96_12385	COG2207	Transcriptional regulator
NMB96_12395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NMB96_12435	COG0753	catalase activity
NMB96_12445	COG0656	L-ascorbic acid biosynthetic process
NMB96_12460	COG2814	Major facilitator Superfamily
NMB96_12480	COG2194	sulfuric ester hydrolase activity
NMB96_12495	COG0745	RESPONSE REGULATOR receiver
NMB96_12500	COG5002	protein histidine kinase activity
NMB96_12510	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
NMB96_12515	COG2894	cell division
NMB96_12530	COG4585	Histidine kinase
NMB96_12535	COG2197	response regulator
NMB96_12550	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NMB96_12590	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
NMB96_12605	COG1595	DNA-templated transcription, initiation
NMB96_12615	COG1946	Acyl-CoA thioesterase
NMB96_12620	COG1024	Enoyl-CoA hydratase
NMB96_12630	COG0824	Thioesterase
NMB96_12635	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NMB96_12645	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NMB96_12650	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NMB96_12660	COG0728	peptidoglycan biosynthetic process
NMB96_12665	COG0196	riboflavin kinase activity
NMB96_12675	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NMB96_12695	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NMB96_12700	COG1845	cytochrome c oxidase, subunit III
NMB96_12705	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NMB96_12720	COG3152	Membrane
NMB96_12730	COG2207	Transcriptional regulator
NMB96_12735	COG0326	Molecular chaperone. Has ATPase activity
NMB96_12745	COG1902	pentaerythritol trinitrate reductase activity
NMB96_12750	COG1366	Belongs to the anti-sigma-factor antagonist family
NMB96_12755	COG1366	Belongs to the anti-sigma-factor antagonist family
NMB96_12760	COG2172	sigma factor antagonist activity
NMB96_12785	COG4771	TonB-dependent receptor
NMB96_12795	COG5507	3-demethylubiquinone-9 3-methyltransferase
NMB96_12800	COG2205	protein histidine kinase activity
NMB96_12805	COG2201	protein-glutamate methylesterase activity
NMB96_12810	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NMB96_12815	COG2205	protein histidine kinase activity
NMB96_12815	COG3437	response regulator, receiver
NMB96_12815	COG3850	Histidine kinase
NMB96_12815	COG4999	Histidine kinase
NMB96_12820	COG0784	Response regulator, receiver
NMB96_12820	COG4191	Histidine kinase
NMB96_12850	COG3534	alpha-L-arabinofuranosidase
NMB96_12905	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NMB96_12930	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NMB96_12935	COG0336	Belongs to the RNA methyltransferase TrmD family
NMB96_12945	COG0534	Mate efflux family protein
NMB96_12955	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
NMB96_12965	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NMB96_13005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NMB96_13025	COG0583	DNA-binding transcription factor activity
NMB96_13030	COG1301	dicarboxylic acid transport
NMB96_13035	COG4948	Mandelate Racemase Muconate Lactonizing
NMB96_13040	COG3250	beta-galactosidase activity
NMB96_13045	COG3867	Arabinogalactan endo-beta-1,4-galactanase
NMB96_13065	COG1960	acyl-CoA dehydrogenase activity
NMB96_13070	COG1024	Enoyl-CoA hydratase
NMB96_13090	COG1250	3-hydroxyacyl-CoA dehydrogenase
NMB96_13090	COG1024	Enoyl-CoA hydratase
NMB96_13105	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NMB96_13130	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NMB96_13135	COG1381	Involved in DNA repair and RecF pathway recombination
NMB96_13155	COG2954	triphosphatase activity
NMB96_13160	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NMB96_13170	COG3046	protein related to deoxyribodipyrimidine photolyase
NMB96_13175	COG1472	Belongs to the glycosyl hydrolase 3 family
NMB96_13180	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NMB96_13185	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NMB96_13190	COG1278	Cold shock
NMB96_13195	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NMB96_13205	COG1201	RNA secondary structure unwinding
NMB96_13210	COG1793	dna ligase
NMB96_13220	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
NMB96_13220	COG1793	dna ligase
NMB96_13250	COG0183	Belongs to the thiolase family
NMB96_13270	COG1451	nucleotide metabolic process
NMB96_13275	COG5487	UPF0391 membrane protein
NMB96_13285	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NMB96_13325	COG1047	Peptidyl-prolyl cis-trans
NMB96_13335	COG2824	Alkylphosphonate utilization operon protein PhnA
NMB96_13355	COG2814	Major facilitator Superfamily
NMB96_13390	COG0392	lysyltransferase activity
NMB96_13390	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NMB96_13400	COG0251	oxidation-reduction process
NMB96_13405	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NMB96_13420	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NMB96_13445	COG1595	DNA-templated transcription, initiation
NMB96_13460	COG2878	Part of a membrane complex involved in electron transport
NMB96_13470	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NMB96_13470	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NMB96_13485	COG1131	(ABC) transporter
NMB96_13490	COG0346	lactoylglutathione lyase activity
NMB96_13495	COG0833	amino acid
NMB96_13500	COG2040	homocysteine
NMB96_13520	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NMB96_13535	COG3039	Transposase
NMB96_13545	COG1695	Transcriptional regulator
NMB96_13565	COG1981	membrane
NMB96_13575	COG0825	malonyl-CoA metabolic process
NMB96_13590	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NMB96_13595	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NMB96_13600	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NMB96_13605	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NMB96_13620	COG0750	zinc metalloprotease
NMB96_13625	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NMB96_13630	COG0575	Belongs to the CDS family
NMB96_13635	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NMB96_13645	COG0528	UMP kinase activity
NMB96_13655	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NMB96_13660	COG0052	Belongs to the universal ribosomal protein uS2 family
NMB96_13705	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
NMB96_13720	COG1393	Belongs to the ArsC family
NMB96_13725	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NMB96_13735	COG0367	asparagine synthase
NMB96_13745	COG4774	siderophore transport
NMB96_13785	COG1566	PFAM secretion protein HlyD family protein
NMB96_13790	COG2814	Major facilitator Superfamily
NMB96_13795	COG1537	nuclear-transcribed mRNA catabolic process, no-go decay
NMB96_13845	COG0339	signal peptide processing
NMB96_13850	COG0386	Belongs to the glutathione peroxidase family
NMB96_13880	COG0288	reversible hydration of carbon dioxide
NMB96_13915	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NMB96_13920	COG0084	hydrolase, TatD family'
NMB96_13935	COG1960	acyl-CoA dehydrogenase activity
NMB96_13950	COG0367	asparagine synthase
NMB96_13960	COG0305	Participates in initiation and elongation during chromosome replication
NMB96_13965	COG0415	Belongs to the DNA photolyase family
NMB96_13975	COG0583	DNA-binding transcription factor activity
NMB96_13985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NMB96_14015	COG3706	GGDEF domain
NMB96_14115	COG1484	DNA-dependent DNA replication
NMB96_14120	COG4584	PFAM Integrase catalytic
NMB96_14145	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NMB96_14160	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NMB96_14170	COG0497	DNA recombination
NMB96_14175	COG1420	regulation of RNA biosynthetic process
NMB96_14180	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NMB96_14195	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
NMB96_14220	COG2274	protein secretion by the type I secretion system
NMB96_14225	COG0583	DNA-binding transcription factor activity
NMB96_14230	COG1132	(ABC) transporter
NMB96_14265	COG2850	peptidyl-arginine hydroxylation
NMB96_14280	COG1253	flavin adenine dinucleotide binding
NMB96_14310	COG1131	(ABC) transporter
NMB96_14315	COG1725	Transcriptional regulator
NMB96_14325	COG0386	Belongs to the glutathione peroxidase family
NMB96_14340	COG2900	Belongs to the SlyX family
NMB96_14365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NMB96_14375	COG0646	methionine synthase
NMB96_14375	COG1410	methionine synthase
NMB96_14390	COG2226	methyltransferase
NMB96_14395	COG1960	acyl-CoA dehydrogenase activity
NMB96_14410	COG0557	exoribonuclease II activity
NMB96_14420	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NMB96_14430	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NMB96_14440	COG0704	Plays a role in the regulation of phosphate uptake
NMB96_14450	COG0581	inorganic phosphate transmembrane transporter activity
NMB96_14455	COG0573	inorganic phosphate transmembrane transporter activity
NMB96_14460	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NMB96_14485	COG0659	secondary active sulfate transmembrane transporter activity
NMB96_14490	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NMB96_14500	COG1024	Enoyl-CoA hydratase
NMB96_14550	COG0488	(ABC) transporter
NMB96_14565	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NMB96_14575	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NMB96_14590	COG2925	Exonuclease
NMB96_14595	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NMB96_14615	COG0288	reversible hydration of carbon dioxide
NMB96_14620	COG2808	Putative FMN-binding domain
NMB96_14640	COG0017	Asparaginyl-tRNA synthetase
NMB96_14645	COG0316	Belongs to the HesB IscA family
NMB96_14670	COG3115	cell septum assembly
NMB96_14680	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NMB96_14685	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NMB96_14690	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
NMB96_14700	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NMB96_14710	COG4993	Dehydrogenase
NMB96_14725	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NMB96_14735	COG2986	histidine ammonia-lyase
NMB96_14740	COG1228	amidohydrolase
NMB96_14775	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
NMB96_14780	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NMB96_14785	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NMB96_14790	COG0077	Prephenate dehydratase
NMB96_14790	COG1605	Chorismate mutase
NMB96_14795	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NMB96_14810	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NMB96_14815	COG0583	DNA-binding transcription factor activity
NMB96_14935	COG0840	transmembrane signaling receptor activity
NMB96_14940	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NMB96_14945	COG0840	transmembrane signaling receptor activity
NMB96_14970	COG2003	Belongs to the UPF0758 family
NMB96_15005	COG0084	hydrolase, TatD family'
NMB96_15075	COG0840	transmembrane signaling receptor activity
NMB96_15095	COG5002	protein histidine kinase activity
NMB96_15095	COG0784	Response regulator, receiver
NMB96_15095	COG2205	protein histidine kinase activity
NMB96_15100	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
NMB96_15105	COG4191	Histidine kinase
NMB96_15105	COG0784	Response regulator, receiver
NMB96_15120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NMB96_15130	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
NMB96_15140	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NMB96_15205	COG2244	polysaccharide biosynthetic process
NMB96_15235	COG2264	protein methyltransferase activity
NMB96_15245	COG0438	transferase activity, transferring glycosyl groups
NMB96_15260	COG1136	(ABC) transporter
NMB96_15265	COG1132	(ABC) transporter
NMB96_15270	COG0477	Major facilitator Superfamily
NMB96_15275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NMB96_15290	COG1253	flavin adenine dinucleotide binding
NMB96_15325	COG0504	CTP synthase activity
NMB96_15340	COG0148	phosphopyruvate hydratase activity
NMB96_15350	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NMB96_15355	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NMB96_15365	COG2840	Smr protein MutS2
NMB96_15370	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NMB96_15375	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NMB96_15380	COG1238	metal cluster binding
NMB96_15395	COG1534	Rna-binding protein
NMB96_15400	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
NMB96_15410	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NMB96_15415	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NMB96_15425	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NMB96_15430	COG1546	Belongs to the CinA family
NMB96_15440	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NMB96_15450	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NMB96_15455	COG2137	regulation of response to DNA damage stimulus
NMB96_15460	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NMB96_15465	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NMB96_15480	COG1741	Belongs to the pirin family
NMB96_15485	COG0583	DNA-binding transcription factor activity
NMB96_15505	COG0351	phosphomethylpyrimidine kinase
NMB96_15505	COG0352	thiamine-phosphate diphosphorylase activity
NMB96_15520	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NMB96_15525	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NMB96_15540	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NMB96_15550	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
NMB96_15565	COG4948	Mandelate Racemase Muconate Lactonizing
NMB96_15570	COG0800	Aldolase
NMB96_15605	COG1501	Belongs to the glycosyl hydrolase 31 family
NMB96_15615	COG1070	Carbohydrate kinase
NMB96_15620	COG2115	Belongs to the xylose isomerase family
NMB96_15625	COG0477	Major facilitator Superfamily
NMB96_15645	COG0860	N-Acetylmuramoyl-L-alanine amidase
NMB96_15665	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NMB96_15670	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NMB96_15675	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NMB96_15680	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NMB96_15705	COG1472	Belongs to the glycosyl hydrolase 3 family
NMB96_15715	COG3706	GGDEF domain
NMB96_15715	COG2203	Gaf domain
NMB96_15715	COG4251	negative regulation of phosphorylation
NMB96_15715	COG5001	Diguanylate cyclase
NMB96_15720	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NMB96_15725	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
NMB96_15735	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NMB96_15740	COG0671	phosphoesterase, PA-phosphatase related
NMB96_15755	COG0697	spore germination
NMB96_15760	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NMB96_15765	COG0167	dihydroorotate dehydrogenase activity
NMB96_15780	COG1012	belongs to the aldehyde dehydrogenase family
NMB96_15830	COG1215	transferase activity, transferring glycosyl groups
NMB96_15835	COG1649	PFAM Uncharacterised BCR, COG1649
NMB96_15835	COG0726	polysaccharide deacetylase
NMB96_15845	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
NMB96_15850	COG0527	aspartate kinase activity
NMB96_15850	COG0460	homoserine dehydrogenase
NMB96_15875	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NMB96_15880	COG0124	histidyl-tRNA synthetase
NMB96_15890	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NMB96_15895	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NMB96_15900	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NMB96_15905	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
NMB96_15905	COG0131	Imidazoleglycerol-phosphate dehydratase
NMB96_15915	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NMB96_15925	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NMB96_15925	COG0140	phosphoribosyl-ATP diphosphatase activity
NMB96_15940	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
NMB96_15955	COG0531	amino acid
NMB96_15960	COG0531	amino acid
NMB96_15970	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NMB96_15975	COG0277	FAD linked oxidase domain protein
NMB96_15995	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NMB96_16010	COG1024	Enoyl-CoA hydratase
NMB96_16030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NMB96_16040	COG0505	Belongs to the CarA family
NMB96_16050	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NMB96_16055	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NMB96_16065	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NMB96_16090	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NMB96_16100	COG2198	Histidine kinase
NMB96_16100	COG2205	protein histidine kinase activity
NMB96_16100	COG0784	Response regulator, receiver
NMB96_16105	COG1024	Enoyl-CoA hydratase
NMB96_16140	COG0318	PFAM AMP-dependent synthetase and ligase
NMB96_16170	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NMB96_16180	COG2201	protein-glutamate methylesterase activity
NMB96_16195	COG0840	transmembrane signaling receptor activity
NMB96_16205	COG0835	chemotaxis
NMB96_16215	COG0840	transmembrane signaling receptor activity
NMB96_16220	COG0840	transmembrane signaling receptor activity
NMB96_16225	COG0840	transmembrane signaling receptor activity
NMB96_16230	COG0840	transmembrane signaling receptor activity
NMB96_16235	COG0840	transmembrane signaling receptor activity
NMB96_16240	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
NMB96_16240	COG3264	Mechanosensitive ion channel
NMB96_16245	COG0840	transmembrane signaling receptor activity
NMB96_16250	COG0840	transmembrane signaling receptor activity
NMB96_16275	COG0840	transmembrane signaling receptor activity
NMB96_16275	COG0840	transmembrane signaling receptor activity
NMB96_16285	COG0840	transmembrane signaling receptor activity
NMB96_16300	COG2198	Histidine kinase
NMB96_16300	COG0643	Histidine kinase
NMB96_16305	COG0745	RESPONSE REGULATOR receiver
NMB96_16315	COG0835	chemotaxis
NMB96_16320	COG1192	Involved in chromosome partitioning
NMB96_16330	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NMB96_16390	COG0643	Histidine kinase
NMB96_16390	COG0784	Response regulator, receiver
NMB96_16390	COG2198	Histidine kinase
NMB96_16440	COG3300	MHYT domain
NMB96_16440	COG5001	Diguanylate cyclase
NMB96_16460	COG3190	flagellar
NMB96_16510	COG1677	Flagellar hook-basal body complex protein FliE
NMB96_16550	COG1028	Short-chain dehydrogenase reductase Sdr
NMB96_16560	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NMB96_16580	COG2201	protein-glutamate methylesterase activity
NMB96_16610	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NMB96_16615	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NMB96_16640	COG1705	Flagellar rod assembly protein muramidase FlgJ
NMB96_16640	COG3951	Flagellar rod assembly protein muramidase FlgJ
NMB96_16660	COG4787	bacterial-type flagellum-dependent cell motility
NMB96_16670	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
NMB96_16675	COG1558	bacterial-type flagellum-dependent cell motility
NMB96_16685	COG0784	Response regulator, receiver
NMB96_16685	COG0835	chemotaxis
NMB96_16705	COG4191	Histidine kinase
NMB96_16745	COG0482	sulfurtransferase activity
NMB96_16760	COG0542	response to heat
NMB96_16770	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
NMB96_16780	COG0492	ferredoxin-NADP+ reductase activity
NMB96_16785	COG1674	ftsk spoiiie
NMB96_16800	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NMB96_16805	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NMB96_16810	COG0183	Belongs to the thiolase family
NMB96_16815	COG1024	Enoyl-CoA hydratase
NMB96_16815	COG1250	3-hydroxyacyl-CoA dehydrogenase
NMB96_16830	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NMB96_16840	COG1426	Protein conserved in bacteria
NMB96_16850	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NMB96_16855	COG1160	GTP binding
NMB96_16860	COG0303	'Molybdopterin
NMB96_16865	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NMB96_16875	COG0708	Exodeoxyribonuclease III
NMB96_16885	COG0303	'Molybdopterin
NMB96_16890	COG0746	molybdenum cofactor guanylyltransferase activity
NMB96_16900	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NMB96_16900	COG1648	precorrin-2 dehydrogenase activity
NMB96_16920	COG2223	nitrite transmembrane transporter activity
NMB96_16925	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NMB96_16935	COG0243	molybdopterin cofactor binding
NMB96_16955	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
NMB96_16965	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NMB96_16985	COG3685	Protein conserved in bacteria
NMB96_17005	COG1484	DNA-dependent DNA replication
NMB96_17010	COG4584	PFAM Integrase catalytic
NMB96_17050	COG2205	protein histidine kinase activity
NMB96_17065	COG3713	MltA-interacting MipA family protein
NMB96_17105	COG4191	Histidine kinase
NMB96_17105	COG0784	Response regulator, receiver
NMB96_17140	COG3781	membrane
NMB96_17145	COG4191	Histidine kinase
NMB96_17150	COG2197	response regulator
NMB96_17180	COG0840	transmembrane signaling receptor activity
NMB96_17290	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
NMB96_17310	COG1054	Belongs to the UPF0176 family
NMB96_17320	COG1530	ribonuclease E activity
NMB96_17330	COG0428	transporter
NMB96_17340	COG2154	pterin-4-alpha-carbinolamine dehydratase
NMB96_17530	COG5599	Phosphatase
NMB96_17545	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NMB96_17550	COG1061	Type III restriction enzyme res subunit
NMB96_17555	COG1002	Type II restriction enzyme, methylase subunits
NMB96_17615	COG0629	single-stranded DNA binding
NMB96_17620	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NMB96_17625	COG0270	DNA (cytosine-5-)-methyltransferase activity
NMB96_17800	COG2003	Belongs to the UPF0758 family
NMB96_17835	COG0560	Phosphoserine phosphatase
NMB96_17835	COG3830	Belongs to the UPF0237 family
NMB96_17845	COG4221	oxidoreductase activity
NMB96_17865	COG1028	Short-chain dehydrogenase reductase Sdr
NMB96_17970	COG0583	DNA-binding transcription factor activity
NMB96_17985	COG0582	viral genome integration into host DNA
NMB96_18030	COG1247	-acetyltransferase
NMB96_18050	COG0322	excinuclease ABC activity
NMB96_18060	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NMB96_18065	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
NMB96_18070	COG1663	tetraacyldisaccharide 4'-kinase activity
NMB96_18075	COG1132	(ABC) transporter
NMB96_18085	COG0811	peptide transport
NMB96_18100	COG1136	(ABC) transporter
NMB96_18105	COG4591	ABC-type transport system involved in lipoprotein release permease component
NMB96_18115	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
NMB96_18120	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NMB96_18135	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
NMB96_18140	COG2009	succinate dehydrogenase
NMB96_18150	COG0354	folic acid binding
NMB96_18160	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NMB96_18165	COG0837	glucose binding
NMB96_18170	COG0363	glucosamine-6-phosphate deaminase activity
NMB96_18175	COG0129	dihydroxy-acid dehydratase activity
NMB96_18180	COG0800	Aldolase
NMB96_18245	COG0784	Response regulator, receiver
NMB96_18245	COG2205	protein histidine kinase activity
NMB96_18245	COG5002	protein histidine kinase activity
NMB96_18250	COG2183	response to ionizing radiation
NMB96_18260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NMB96_18260	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
NMB96_18275	COG3243	poly(R)-hydroxyalkanoic acid synthase
NMB96_18285	COG1183	phosphatidylcholine synthase activity
NMB96_18290	COG1028	Short-chain dehydrogenase reductase Sdr
NMB96_18315	COG0668	transmembrane transport
NMB96_18320	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
NMB96_18335	COG1914	H( )-stimulated, divalent metal cation uptake system
NMB96_18360	COG2814	Major facilitator Superfamily
NMB96_18375	COG1335	isochorismatase
NMB96_18385	COG4585	Histidine kinase
NMB96_18390	COG2197	response regulator
NMB96_18425	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NMB96_18435	COG0475	glutathione-regulated potassium exporter activity
NMB96_18435	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NMB96_18440	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NMB96_18450	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NMB96_18455	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
NMB96_18465	COG0776	regulation of translation
NMB96_18475	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NMB96_18490	COG2957	Belongs to the agmatine deiminase family
NMB96_18495	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NMB96_18520	COG0395	ABC-type sugar transport system, permease component
NMB96_18525	COG1175	transmembrane transport
NMB96_18530	COG1653	transport
NMB96_18555	COG2350	Protein conserved in bacteria
NMB96_18560	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NMB96_18565	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NMB96_18570	COG1187	pseudouridine synthase activity
NMB96_18585	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NMB96_18590	COG0436	Aminotransferase
NMB96_18615	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
NMB96_18650	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NMB96_18655	COG4988	ABC transporter
NMB96_18665	COG1294	oxidase, subunit
NMB96_18700	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NMB96_18715	COG0165	Argininosuccinate lyase
NMB96_18730	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NMB96_18735	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NMB96_18740	COG0137	argininosuccinate synthase activity
NMB96_18745	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NMB96_18760	COG2166	iron-sulfur cluster assembly
NMB96_18780	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NMB96_18795	COG4303	Ethanolamine ammonia lyase large subunit
NMB96_18800	COG4302	ethanolamine ammonia-lyase activity
NMB96_18820	COG4677	pectinesterase activity
NMB96_18845	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NMB96_18850	COG0402	S-adenosylhomocysteine deaminase activity
NMB96_18870	COG3300	MHYT domain
NMB96_18870	COG5001	Diguanylate cyclase
NMB96_18885	COG0483	inositol monophosphate 1-phosphatase activity
NMB96_18890	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NMB96_18905	COG0488	(ABC) transporter
NMB96_18910	COG0513	Belongs to the DEAD box helicase family
NMB96_18920	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
NMB96_18930	COG0625	glutathione transferase activity
NMB96_18945	COG4681	YaeQ
NMB96_18950	COG2081	HI0933 family
NMB96_18955	COG3300	MHYT domain
NMB96_18955	COG5001	Diguanylate cyclase
NMB96_18960	COG0501	Belongs to the peptidase M48B family
NMB96_18965	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NMB96_18970	COG1028	Short-chain dehydrogenase reductase Sdr
NMB96_18990	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NMB96_18995	COG0860	N-Acetylmuramoyl-L-alanine amidase
NMB96_19005	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NMB96_19005	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NMB96_19010	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NMB96_19025	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NMB96_19060	COG0835	chemotaxis
NMB96_19065	COG0840	transmembrane signaling receptor activity
NMB96_19070	COG2094	Belongs to the DNA glycosylase MPG family
NMB96_19075	COG1201	RNA secondary structure unwinding
NMB96_19085	COG2969	positive regulation of protein catabolic process
NMB96_19090	COG0625	glutathione transferase activity
NMB96_19095	COG2857	Cytochrome c1
NMB96_19100	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NMB96_19105	COG0723	plastoquinol--plastocyanin reductase activity
NMB96_19110	COG0741	lytic transglycosylase activity
NMB96_19125	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NMB96_19130	COG1702	phosphate starvation-inducible protein PhoH
NMB96_19140	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NMB96_19150	COG4535	Mg2 and Co2 transporter CorC
NMB96_19165	COG1012	belongs to the aldehyde dehydrogenase family
NMB96_19175	COG1177	transmembrane transport
NMB96_19180	COG1176	ABC-type spermidine putrescine transport system, permease component I
NMB96_19190	COG3842	ATPase activity
NMB96_19225	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NMB96_19230	COG0174	glutamine synthetase
NMB96_19235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NMB96_19245	COG0477	Major facilitator Superfamily
NMB96_19255	COG0243	molybdopterin cofactor binding
NMB96_19265	COG2223	nitrite transmembrane transporter activity
NMB96_19270	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NMB96_19280	COG2733	membrane
NMB96_19285	COG5002	protein histidine kinase activity
NMB96_19285	COG2205	protein histidine kinase activity
NMB96_19285	COG0784	Response regulator, receiver
NMB96_19295	COG0477	Major facilitator Superfamily
NMB96_19305	COG0604	alcohol dehydrogenase
NMB96_19310	COG0300	oxidoreductase activity
NMB96_19330	COG3321	synthase
NMB96_19330	COG0604	alcohol dehydrogenase
NMB96_19335	COG2902	Dehydrogenase
NMB96_19345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NMB96_19350	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NMB96_19355	COG1609	Transcriptional regulator
NMB96_19360	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NMB96_19360	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NMB96_19365	COG1105	Belongs to the carbohydrate kinase PfkB family
NMB96_19370	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NMB96_19370	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NMB96_19415	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NMB96_19425	COG1862	Preprotein translocase
NMB96_19475	COG3291	Pkd domain containing protein
NMB96_19490	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NMB96_19505	COG0742	ribosomal rna small subunit methyltransferase
NMB96_19605	COG0531	amino acid
NMB96_19620	COG0006	proline dipeptidase activity
NMB96_19630	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NMB96_19645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NMB96_19650	COG3938	Belongs to the proline racemase family
NMB96_19660	COG0552	protein localization to endoplasmic reticulum
NMB96_19665	COG1194	a g-specific adenine glycosylase
NMB96_19680	COG4191	Histidine kinase
NMB96_19680	COG0784	Response regulator, receiver
NMB96_19690	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NMB96_19755	COG3040	lipid binding
NMB96_19765	COG1960	acyl-CoA dehydrogenase activity
NMB96_19775	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NMB96_19795	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NMB96_19800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NMB96_19805	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NMB96_19830	COG0438	transferase activity, transferring glycosyl groups
NMB96_19840	COG0438	transferase activity, transferring glycosyl groups
NMB96_19845	COG0438	transferase activity, transferring glycosyl groups
NMB96_19895	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NMB96_19895	COG0072	phenylalanine-tRNA ligase activity
NMB96_19900	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NMB96_19915	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NMB96_19920	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NMB96_20010	COG3702	type iv secretory pathway
NMB96_20030	COG2948	multi-organism process
NMB96_20050	COG3505	Type IV secretory pathway VirD4
NMB96_20060	COG0582	viral genome integration into host DNA
NMB96_20150	COG0556	nucleotide-excision repair
NMB96_20155	COG4969	Belongs to the N-Me-Phe pilin family
NMB96_20195	COG1611	Belongs to the LOG family
NMB96_20205	COG2095	MarC family integral membrane protein
NMB96_20210	COG1028	Short-chain dehydrogenase reductase Sdr
NMB96_20215	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NMB96_20260	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NMB96_20265	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NMB96_20270	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NMB96_20280	COG0195	Participates in both transcription termination and antitermination
NMB96_20285	COG0779	Required for maturation of 30S ribosomal subunits
NMB96_20295	COG1007	ATP synthesis coupled electron transport
NMB96_20315	COG0839	Belongs to the complex I subunit 6 family
NMB96_20325	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NMB96_20335	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
NMB96_20340	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
NMB96_20345	COG0649	NAD binding
NMB96_20350	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NMB96_20360	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NMB96_20380	COG4221	oxidoreductase activity
NMB96_20410	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NMB96_20420	COG0159	tryptophan synthase activity
NMB96_20430	COG0133	tryptophan synthase activity
NMB96_20445	COG0101	tRNA pseudouridine synthase activity
NMB96_20460	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NMB96_20465	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NMB96_20480	COG2890	protein-(glutamine-N5) methyltransferase activity
NMB96_20490	COG0688	phosphatidylethanolamine metabolic process
NMB96_20500	COG0433	COG0433 Predicted ATPase
NMB96_20510	COG0494	nUDIX hydrolase
NMB96_20530	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NMB96_20580	COG4695	Portal protein
NMB96_20625	COG3179	chitinase
NMB96_20825	COG0717	Belongs to the dCTP deaminase family
NMB96_20830	COG0489	protein tyrosine kinase activity
NMB96_20855	COG3590	peptidase
NMB96_20860	COG3590	peptidase
NMB96_20880	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NMB96_20890	COG2311	Membrane
NMB96_20895	COG1047	Peptidyl-prolyl cis-trans
NMB96_20905	COG0791	NLP P60 protein
NMB96_20920	COG1301	dicarboxylic acid transport
NMB96_20925	COG1785	Belongs to the alkaline phosphatase family
NMB96_20930	COG0037	tRNA processing
NMB96_20935	COG1722	exodeoxyribonuclease VII activity
NMB96_20940	COG0142	geranyltranstransferase activity
NMB96_20945	COG4104	PAAR repeat-containing protein
NMB96_20955	COG0312	modulator of DNA gyrase
NMB96_20960	COG3028	Belongs to the UPF0307 family
NMB96_20965	COG0312	modulator of DNA gyrase
NMB96_20975	COG3164	Protein of unknown function
NMB96_21000	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NMB96_21035	COG0495	leucyl-tRNA aminoacylation
NMB96_21045	COG3118	belongs to the thioredoxin family
NMB96_21055	COG2155	Conserved Protein
NMB96_21095	COG1132	(ABC) transporter
NMB96_21105	COG0475	glutathione-regulated potassium exporter activity
NMB96_21115	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NMB96_21135	COG1187	pseudouridine synthase activity
NMB96_21140	COG5002	protein histidine kinase activity
NMB96_21140	COG5001	Diguanylate cyclase
NMB96_21150	COG1595	DNA-templated transcription, initiation
NMB96_21270	COG2814	Major facilitator Superfamily
NMB96_21275	COG0583	DNA-binding transcription factor activity
NMB96_21310	COG0667	Aldo Keto reductase
NMB96_21315	COG1309	transcriptional regulator
NMB96_21325	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NMB96_21340	COG0735	belongs to the Fur family
NMB96_21345	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NMB96_21370	COG4452	Inner membrane protein CreD
NMB96_21375	COG2205	protein histidine kinase activity
NMB96_21380	COG0745	RESPONSE REGULATOR receiver
NMB96_21385	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
NMB96_21395	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NMB96_21435	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NMB96_21440	COG1309	transcriptional regulator
NMB96_21460	COG2198	Histidine kinase
NMB96_21460	COG0643	Histidine kinase
NMB96_21465	COG0840	transmembrane signaling receptor activity
NMB96_21470	COG0835	chemotaxis
NMB96_21475	COG2202	Pas domain
NMB96_21475	COG2199	diguanylate cyclase activity
NMB96_21475	COG2200	EAL domain
NMB96_21480	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NMB96_21490	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NMB96_21495	COG3590	peptidase
NMB96_21505	COG0588	phosphoglycerate mutase activity
NMB96_21510	COG1515	deoxyribonuclease V activity
NMB96_21515	COG1741	Belongs to the pirin family
NMB96_21530	COG1741	Belongs to the pirin family
NMB96_21535	COG1966	Carbon starvation protein
NMB96_21540	COG2879	small protein
NMB96_21550	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NMB96_21580	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NMB96_21585	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NMB96_21590	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
NMB96_21595	COG2080	2 iron, 2 sulfur cluster binding
NMB96_21600	COG5001	Diguanylate cyclase
NMB96_21600	COG3706	GGDEF domain
NMB96_21600	COG2203	Gaf domain
NMB96_21600	COG4251	negative regulation of phosphorylation
NMB96_21605	COG1228	amidohydrolase
NMB96_21620	COG0629	single-stranded DNA binding
NMB96_21625	COG0142	geranyltranstransferase activity
NMB96_21645	COG0527	aspartate kinase activity
NMB96_21650	COG0384	phenazine biosynthesis protein PhzF
NMB96_21655	COG0384	phenazine biosynthesis protein PhzF
NMB96_21665	COG1764	response to oxidative stress
NMB96_21675	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NMB96_21680	COG1678	Uncharacterized ACR, COG1678
NMB96_21685	COG0519	Catalyzes the synthesis of GMP from XMP
NMB96_21710	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NMB96_21725	COG4942	peptidase
NMB96_21750	COG1959	2 iron, 2 sulfur cluster binding
NMB96_21755	COG0719	Fe-S assembly protein
NMB96_21760	COG0396	ATPase activity
NMB96_21765	COG0719	Fe-S assembly protein
NMB96_21770	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NMB96_21790	COG4774	siderophore transport
NMB96_21795	COG3128	pkhd-type hydroxylase
NMB96_21820	COG1477	protein flavinylation
NMB96_21825	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NMB96_21835	COG1555	photosystem II stabilization
NMB96_21840	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NMB96_21850	COG3178	'Phosphotransferase
NMB96_21855	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NMB96_21865	COG0628	permease
NMB96_21880	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NMB96_21900	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NMB96_21905	COG0271	Belongs to the BolA IbaG family
NMB96_21915	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
NMB96_21925	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
NMB96_21930	COG1137	ATPase activity
NMB96_21945	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NMB96_21965	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NMB96_21970	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NMB96_21975	COG2239	Acts as a magnesium transporter
NMB96_21985	COG1294	oxidase, subunit
NMB96_21990	COG1271	oxidase subunit
NMB96_22000	COG1113	amino acid transport
NMB96_22015	COG2197	response regulator
NMB96_22020	COG0531	amino acid
NMB96_22075	COG0789	Transcriptional regulator
NMB96_22080	COG2814	Major facilitator Superfamily
NMB96_22085	COG0754	glutathionylspermidine amidase activity
NMB96_22110	COG1842	Phage shock protein A
NMB96_22125	COG0259	pyridoxamine-phosphate oxidase activity
NMB96_22130	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NMB96_22135	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NMB96_22145	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NMB96_22170	COG0745	RESPONSE REGULATOR receiver
NMB96_22170	COG2205	protein histidine kinase activity
NMB96_22170	COG3292	Two component regulator propeller
NMB96_22175	COG0784	Response regulator, receiver
NMB96_22175	COG2198	Histidine kinase
NMB96_22175	COG2205	protein histidine kinase activity
NMB96_22180	COG2205	protein histidine kinase activity
NMB96_22180	COG0784	Response regulator, receiver
NMB96_22180	COG2198	Histidine kinase
NMB96_22185	COG2353	YceI-like domain
NMB96_22190	COG3038	cytochrome b561
NMB96_22200	COG1278	Cold shock
NMB96_22210	COG1760	l-serine dehydratase
NMB96_22220	COG0527	aspartate kinase activity
NMB96_22220	COG0460	homoserine dehydrogenase
NMB96_22225	COG0626	cystathionine gamma-synthase activity
NMB96_22230	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NMB96_22240	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NMB96_22245	COG1272	protein, Hemolysin III
NMB96_22250	COG2982	Protein involved in outer membrane biogenesis
NMB96_22260	COG0517	IMP dehydrogenase activity
NMB96_22260	COG0516	GMP reductase activity
NMB96_22265	COG0463	Glycosyl transferase, family 2
NMB96_22270	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NMB96_22275	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NMB96_22290	COG1309	transcriptional regulator
NMB96_22300	COG1960	acyl-CoA dehydrogenase activity
NMB96_22330	COG0509	glycine decarboxylation via glycine cleavage system
NMB96_22335	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NMB96_22340	COG1742	UPF0060 membrane protein
NMB96_22345	COG3956	TIGRFAM MazG family protein
NMB96_22350	COG1218	3'(2'),5'-bisphosphate nucleotidase
NMB96_22355	COG0494	nUDIX hydrolase
NMB96_22365	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NMB96_22370	COG0837	glucose binding
NMB96_22385	COG1388	LysM domain
NMB96_22385	COG3858	chitin binding
NMB96_22390	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NMB96_22400	COG1472	Belongs to the glycosyl hydrolase 3 family
NMB96_22415	COG0531	amino acid
NMB96_22425	COG1486	melibiose metabolic process
NMB96_22435	COG3537	Alpha-1,2-mannosidase
NMB96_22470	COG1446	asparaginase
NMB96_22475	COG2304	oxidoreductase activity
NMB96_22480	COG1595	DNA-templated transcription, initiation
NMB96_22500	COG2201	protein-glutamate methylesterase activity
NMB96_22505	COG2198	Histidine kinase
NMB96_22505	COG0643	Histidine kinase
NMB96_22505	COG0784	Response regulator, receiver
NMB96_22510	COG0840	transmembrane signaling receptor activity
NMB96_22515	COG0835	chemotaxis
NMB96_22530	COG0189	ligase activity
NMB96_22540	COG1397	ADP-ribosylglycohydrolase
NMB96_22550	COG1199	ATP-dependent helicase activity
NMB96_22560	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NMB96_22565	COG1216	Glycosyl transferase, family 2
NMB96_22575	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NMB96_22585	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NMB96_22590	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
NMB96_22600	COG0535	radical SAM domain protein
NMB96_22610	COG0837	glucose binding
NMB96_22620	COG1643	Atp-dependent helicase
NMB96_22625	COG0783	Belongs to the Dps family
NMB96_22630	COG0514	ATP-dependent DNA helicase (RecQ)
NMB96_22645	COG1187	pseudouridine synthase activity
NMB96_22655	COG0840	transmembrane signaling receptor activity
NMB96_22680	COG3920	Histidine kinase
NMB96_22685	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NMB96_22695	COG0582	viral genome integration into host DNA
NMB96_22715	COG4983	Phage plasmid primase, P4 family domain protein
NMB96_22780	COG0667	Aldo Keto reductase
NMB96_22785	COG0602	queuosine metabolic process
NMB96_22795	COG2885	chlorophyll binding
NMB96_22810	COG0848	biopolymer transport protein
NMB96_22820	COG0824	Thioesterase
NMB96_22825	COG2255	four-way junction helicase activity
NMB96_22865	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NMB96_22885	COG0477	Major facilitator Superfamily
NMB96_22910	COG2951	lytic endotransglycosylase activity
NMB96_22915	COG0488	(ABC) transporter
NMB96_22940	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NMB96_22940	COG4651	solute:proton antiporter activity
NMB96_22950	COG4772	TonB-dependent receptor
NMB96_22955	COG1181	Belongs to the D-alanine--D-alanine ligase family
NMB96_22960	COG4264	IucA IucC family
NMB96_22970	COG4264	IucA IucC family
NMB96_22975	COG0019	diaminopimelate decarboxylase activity
NMB96_22990	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
NMB96_23000	COG4206	TonB-dependent receptor
NMB96_23015	COG0542	response to heat
NMB96_23020	COG1116	anion transmembrane transporter activity
NMB96_23025	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NMB96_23030	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NMB96_23035	COG0667	Aldo Keto reductase
NMB96_23045	COG4771	TonB-dependent receptor
NMB96_23090	COG1877	trehalose-phosphatase activity
NMB96_23095	COG3387	PFAM Glycoside hydrolase 15-related
NMB96_23110	COG0840	transmembrane signaling receptor activity
NMB96_23115	COG3011	Protein conserved in bacteria
NMB96_23130	COG0564	pseudouridine synthase activity
NMB96_23135	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NMB96_23145	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NMB96_23145	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NMB96_23170	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NMB96_23175	COG0045	succinate-CoA ligase (ADP-forming) activity
NMB96_23215	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NMB96_23240	COG0745	RESPONSE REGULATOR receiver
NMB96_23245	COG0189	ligase activity
NMB96_23295	COG0840	transmembrane signaling receptor activity
NMB96_23305	COG1238	metal cluster binding
NMB96_23310	COG0583	DNA-binding transcription factor activity