locus-tag	class	description
NDY25_00055	COG0653	protein targeting
NDY25_00070	COG2154	pterin-4-alpha-carbinolamine dehydratase
NDY25_00080	COG0428	transporter
NDY25_00100	COG1054	Belongs to the UPF0176 family
NDY25_00120	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
NDY25_00170	COG1304	FMN binding
NDY25_00175	COG1247	-acetyltransferase
NDY25_00190	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NDY25_00195	COG0322	excinuclease ABC activity
NDY25_00205	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NDY25_00210	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
NDY25_00215	COG1663	tetraacyldisaccharide 4'-kinase activity
NDY25_00220	COG1132	(ABC) transporter
NDY25_00230	COG0811	peptide transport
NDY25_00245	COG1136	(ABC) transporter
NDY25_00250	COG4591	ABC-type transport system involved in lipoprotein release permease component
NDY25_00260	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
NDY25_00265	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NDY25_00280	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
NDY25_00285	COG2009	succinate dehydrogenase
NDY25_00305	COG0837	glucose binding
NDY25_00310	COG0363	glucosamine-6-phosphate deaminase activity
NDY25_00315	COG0129	dihydroxy-acid dehydratase activity
NDY25_00320	COG0800	Aldolase
NDY25_00385	COG0784	Response regulator, receiver
NDY25_00385	COG2205	protein histidine kinase activity
NDY25_00385	COG5002	protein histidine kinase activity
NDY25_00390	COG2183	response to ionizing radiation
NDY25_00415	COG3243	poly(R)-hydroxyalkanoic acid synthase
NDY25_00425	COG1183	phosphatidylcholine synthase activity
NDY25_00455	COG0668	transmembrane transport
NDY25_00460	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
NDY25_00475	COG1914	H( )-stimulated, divalent metal cation uptake system
NDY25_00505	COG2814	Major facilitator Superfamily
NDY25_00520	COG1335	isochorismatase
NDY25_00535	COG2197	response regulator
NDY25_00580	COG0583	DNA-binding transcription factor activity
NDY25_00600	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NDY25_00605	COG0077	Prephenate dehydratase
NDY25_00605	COG1605	Chorismate mutase
NDY25_00610	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NDY25_00615	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NDY25_00620	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
NDY25_00655	COG1228	amidohydrolase
NDY25_00660	COG2986	histidine ammonia-lyase
NDY25_00670	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NDY25_00700	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NDY25_00710	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
NDY25_00715	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NDY25_00720	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NDY25_00725	COG3115	cell septum assembly
NDY25_00750	COG0316	Belongs to the HesB IscA family
NDY25_00755	COG0017	Asparaginyl-tRNA synthetase
NDY25_00770	COG2808	Putative FMN-binding domain
NDY25_00775	COG0288	reversible hydration of carbon dioxide
NDY25_00795	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NDY25_00800	COG2925	Exonuclease
NDY25_00825	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NDY25_00840	COG0488	(ABC) transporter
NDY25_00890	COG1024	Enoyl-CoA hydratase
NDY25_00900	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NDY25_00905	COG0659	secondary active sulfate transmembrane transporter activity
NDY25_00930	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NDY25_00935	COG0573	inorganic phosphate transmembrane transporter activity
NDY25_00940	COG0581	inorganic phosphate transmembrane transporter activity
NDY25_00950	COG0704	Plays a role in the regulation of phosphate uptake
NDY25_00960	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NDY25_00970	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NDY25_00980	COG0557	exoribonuclease II activity
NDY25_00995	COG1960	acyl-CoA dehydrogenase activity
NDY25_01000	COG2226	methyltransferase
NDY25_01005	COG1410	methionine synthase
NDY25_01005	COG0646	methionine synthase
NDY25_01010	COG1410	methionine synthase
NDY25_01010	COG0646	methionine synthase
NDY25_01020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NDY25_01045	COG2900	Belongs to the SlyX family
NDY25_01060	COG0386	Belongs to the glutathione peroxidase family
NDY25_01070	COG1725	Transcriptional regulator
NDY25_01075	COG1131	(ABC) transporter
NDY25_01105	COG1253	flavin adenine dinucleotide binding
NDY25_01120	COG2850	peptidyl-arginine hydroxylation
NDY25_01155	COG1619	proteins homologs of microcin C7 resistance protein MccF
NDY25_01165	COG1132	(ABC) transporter
NDY25_01170	COG0583	DNA-binding transcription factor activity
NDY25_01175	COG2274	protein secretion by the type I secretion system
NDY25_01195	COG0287	Prephenate dehydrogenase
NDY25_01195	COG1605	Chorismate mutase
NDY25_01200	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
NDY25_01215	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NDY25_01220	COG1420	regulation of RNA biosynthetic process
NDY25_01225	COG0497	DNA recombination
NDY25_01235	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NDY25_01250	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NDY25_01395	COG1611	Belongs to the LOG family
NDY25_01405	COG2095	MarC family integral membrane protein
NDY25_01410	COG1028	Short-chain dehydrogenase reductase Sdr
NDY25_01415	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NDY25_01460	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NDY25_01465	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NDY25_01470	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NDY25_01480	COG0195	Participates in both transcription termination and antitermination
NDY25_01485	COG0779	Required for maturation of 30S ribosomal subunits
NDY25_01495	COG1007	ATP synthesis coupled electron transport
NDY25_01515	COG0839	Belongs to the complex I subunit 6 family
NDY25_01525	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NDY25_01535	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
NDY25_01540	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
NDY25_01545	COG0649	NAD binding
NDY25_01550	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NDY25_01560	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NDY25_01580	COG4221	oxidoreductase activity
NDY25_01610	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NDY25_01620	COG0159	tryptophan synthase activity
NDY25_01630	COG0133	tryptophan synthase activity
NDY25_01645	COG0101	tRNA pseudouridine synthase activity
NDY25_01660	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NDY25_01665	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NDY25_01680	COG2890	protein-(glutamine-N5) methyltransferase activity
NDY25_01690	COG0688	phosphatidylethanolamine metabolic process
NDY25_01700	COG0433	COG0433 Predicted ATPase
NDY25_01710	COG0494	nUDIX hydrolase
NDY25_01755	COG0717	Belongs to the dCTP deaminase family
NDY25_01760	COG0489	protein tyrosine kinase activity
NDY25_01780	COG3590	peptidase
NDY25_01785	COG3590	peptidase
NDY25_01805	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NDY25_01815	COG2311	Membrane
NDY25_01820	COG1047	Peptidyl-prolyl cis-trans
NDY25_01830	COG0791	NLP P60 protein
NDY25_01860	COG4191	Histidine kinase
NDY25_01875	COG1301	dicarboxylic acid transport
NDY25_01880	COG1785	Belongs to the alkaline phosphatase family
NDY25_01885	COG0037	tRNA processing
NDY25_01890	COG1722	exodeoxyribonuclease VII activity
NDY25_01895	COG0142	geranyltranstransferase activity
NDY25_01910	COG0312	modulator of DNA gyrase
NDY25_01920	COG0312	modulator of DNA gyrase
NDY25_01930	COG3164	Protein of unknown function
NDY25_01955	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NDY25_01975	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NDY25_01990	COG0495	leucyl-tRNA aminoacylation
NDY25_02000	COG3118	belongs to the thioredoxin family
NDY25_02010	COG2155	Conserved Protein
NDY25_02050	COG1132	(ABC) transporter
NDY25_02060	COG0475	glutathione-regulated potassium exporter activity
NDY25_02070	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NDY25_02090	COG1187	pseudouridine synthase activity
NDY25_02095	COG5002	protein histidine kinase activity
NDY25_02095	COG5001	Diguanylate cyclase
NDY25_02105	COG1595	DNA-templated transcription, initiation
NDY25_02220	COG0667	Aldo Keto reductase
NDY25_02225	COG2814	Major facilitator Superfamily
NDY25_02230	COG0583	DNA-binding transcription factor activity
NDY25_02260	COG0667	Aldo Keto reductase
NDY25_02265	COG1309	transcriptional regulator
NDY25_02275	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NDY25_02290	COG0735	belongs to the Fur family
NDY25_02295	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NDY25_02320	COG4452	Inner membrane protein CreD
NDY25_02325	COG2205	protein histidine kinase activity
NDY25_02330	COG0745	RESPONSE REGULATOR receiver
NDY25_02340	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
NDY25_02350	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NDY25_02395	COG2198	Histidine kinase
NDY25_02395	COG0643	Histidine kinase
NDY25_02400	COG0840	transmembrane signaling receptor activity
NDY25_02405	COG0835	chemotaxis
NDY25_02410	COG2202	Pas domain
NDY25_02410	COG2200	EAL domain
NDY25_02410	COG2199	diguanylate cyclase activity
NDY25_02415	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NDY25_02425	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NDY25_02430	COG3590	peptidase
NDY25_02440	COG0588	phosphoglycerate mutase activity
NDY25_02445	COG1515	deoxyribonuclease V activity
NDY25_02450	COG1741	Belongs to the pirin family
NDY25_02465	COG1741	Belongs to the pirin family
NDY25_02470	COG1966	Carbon starvation protein
NDY25_02475	COG2879	small protein
NDY25_02480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NDY25_02510	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NDY25_02515	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NDY25_02520	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
NDY25_02525	COG2080	2 iron, 2 sulfur cluster binding
NDY25_02530	COG4251	negative regulation of phosphorylation
NDY25_02530	COG2203	Gaf domain
NDY25_02530	COG3706	GGDEF domain
NDY25_02530	COG5001	Diguanylate cyclase
NDY25_02545	COG0629	single-stranded DNA binding
NDY25_02550	COG0142	geranyltranstransferase activity
NDY25_02570	COG0527	aspartate kinase activity
NDY25_02575	COG0384	phenazine biosynthesis protein PhzF
NDY25_02580	COG0384	phenazine biosynthesis protein PhzF
NDY25_02590	COG1764	response to oxidative stress
NDY25_02600	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NDY25_02605	COG1678	Uncharacterized ACR, COG1678
NDY25_02610	COG0519	Catalyzes the synthesis of GMP from XMP
NDY25_02630	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NDY25_02645	COG4942	peptidase
NDY25_02670	COG1959	2 iron, 2 sulfur cluster binding
NDY25_02675	COG0719	Fe-S assembly protein
NDY25_02680	COG0396	ATPase activity
NDY25_02685	COG0719	Fe-S assembly protein
NDY25_02690	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NDY25_02705	COG4774	siderophore transport
NDY25_02710	COG3128	pkhd-type hydroxylase
NDY25_02735	COG1477	protein flavinylation
NDY25_02750	COG1555	photosystem II stabilization
NDY25_02765	COG3178	'Phosphotransferase
NDY25_02790	COG0288	reversible hydration of carbon dioxide
NDY25_02815	COG0386	Belongs to the glutathione peroxidase family
NDY25_02820	COG0339	signal peptide processing
NDY25_02875	COG2814	Major facilitator Superfamily
NDY25_02880	COG1566	PFAM secretion protein HlyD family protein
NDY25_02920	COG4774	siderophore transport
NDY25_02930	COG0367	asparagine synthase
NDY25_02940	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NDY25_02945	COG1393	Belongs to the ArsC family
NDY25_02960	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
NDY25_03005	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NDY25_03015	COG0528	UMP kinase activity
NDY25_03025	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NDY25_03030	COG0575	Belongs to the CDS family
NDY25_03035	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NDY25_03040	COG0750	zinc metalloprotease
NDY25_03055	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NDY25_03060	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NDY25_03065	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NDY25_03070	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NDY25_03085	COG0825	malonyl-CoA metabolic process
NDY25_03095	COG1981	membrane
NDY25_03115	COG1695	Transcriptional regulator
NDY25_03140	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NDY25_03160	COG2040	homocysteine
NDY25_03165	COG0833	amino acid
NDY25_03170	COG0346	lactoylglutathione lyase activity
NDY25_03175	COG1131	(ABC) transporter
NDY25_03190	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NDY25_03190	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NDY25_03200	COG2878	Part of a membrane complex involved in electron transport
NDY25_03215	COG1595	DNA-templated transcription, initiation
NDY25_03240	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NDY25_03255	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NDY25_03260	COG0251	oxidation-reduction process
NDY25_03270	COG0392	lysyltransferase activity
NDY25_03270	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NDY25_03305	COG2814	Major facilitator Superfamily
NDY25_03310	COG1902	pentaerythritol trinitrate reductase activity
NDY25_03325	COG2824	Alkylphosphonate utilization operon protein PhnA
NDY25_03335	COG1047	Peptidyl-prolyl cis-trans
NDY25_03375	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NDY25_03385	COG5487	UPF0391 membrane protein
NDY25_03390	COG1451	nucleotide metabolic process
NDY25_03410	COG0183	Belongs to the thiolase family
NDY25_03440	COG1793	dna ligase
NDY25_03440	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
NDY25_03450	COG1793	dna ligase
NDY25_03455	COG1201	RNA secondary structure unwinding
NDY25_03465	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NDY25_03470	COG1278	Cold shock
NDY25_03475	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NDY25_03480	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NDY25_03485	COG1472	Belongs to the glycosyl hydrolase 3 family
NDY25_03490	COG3046	protein related to deoxyribodipyrimidine photolyase
NDY25_03495	COG1233	COG1233 Phytoene dehydrogenase and related
NDY25_03500	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NDY25_03505	COG2954	triphosphatase activity
NDY25_03525	COG1381	Involved in DNA repair and RecF pathway recombination
NDY25_03530	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NDY25_03555	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NDY25_03570	COG1024	Enoyl-CoA hydratase
NDY25_03570	COG1250	3-hydroxyacyl-CoA dehydrogenase
NDY25_03580	COG0457	Tetratricopeptide repeat
NDY25_03615	COG1024	Enoyl-CoA hydratase
NDY25_03620	COG1960	acyl-CoA dehydrogenase activity
NDY25_03640	COG3867	Arabinogalactan endo-beta-1,4-galactanase
NDY25_03645	COG3250	beta-galactosidase activity
NDY25_03655	COG0436	Aminotransferase
NDY25_03670	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NDY25_03695	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NDY25_03705	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
NDY25_03715	COG0534	Mate efflux family protein
NDY25_03725	COG0336	Belongs to the RNA methyltransferase TrmD family
NDY25_03730	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NDY25_03760	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NDY25_03810	COG2205	protein histidine kinase activity
NDY25_03810	COG3850	Histidine kinase
NDY25_03810	COG3437	response regulator, receiver
NDY25_03810	COG4999	Histidine kinase
NDY25_03815	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NDY25_03820	COG2201	protein-glutamate methylesterase activity
NDY25_03825	COG2205	protein histidine kinase activity
NDY25_03830	COG5507	3-demethylubiquinone-9 3-methyltransferase
NDY25_03850	COG4771	TonB-dependent receptor
NDY25_03875	COG2172	sigma factor antagonist activity
NDY25_03880	COG1366	Belongs to the anti-sigma-factor antagonist family
NDY25_03885	COG1366	Belongs to the anti-sigma-factor antagonist family
NDY25_03890	COG1902	pentaerythritol trinitrate reductase activity
NDY25_03900	COG0326	Molecular chaperone. Has ATPase activity
NDY25_03905	COG2207	Transcriptional regulator
NDY25_03915	COG3152	Membrane
NDY25_03930	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NDY25_03935	COG1845	cytochrome c oxidase, subunit III
NDY25_03940	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NDY25_03960	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NDY25_03970	COG0196	riboflavin kinase activity
NDY25_03985	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NDY25_03990	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NDY25_04000	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NDY25_04005	COG0824	Thioesterase
NDY25_04015	COG1024	Enoyl-CoA hydratase
NDY25_04020	COG1946	Acyl-CoA thioesterase
NDY25_04040	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
NDY25_04090	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NDY25_04105	COG2197	response regulator
NDY25_04110	COG4585	Histidine kinase
NDY25_04125	COG2894	cell division
NDY25_04130	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
NDY25_04140	COG5002	protein histidine kinase activity
NDY25_04145	COG0745	RESPONSE REGULATOR receiver
NDY25_04160	COG2194	sulfuric ester hydrolase activity
NDY25_04180	COG2814	Major facilitator Superfamily
NDY25_04185	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NDY25_04185	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NDY25_04195	COG0656	L-ascorbic acid biosynthetic process
NDY25_04205	COG0753	catalase activity
NDY25_04210	COG1917	Cupin 2, conserved barrel domain protein
NDY25_04210	COG2207	Transcriptional regulator
NDY25_04220	COG0823	Involved in the tonB-independent uptake of proteins
NDY25_04220	COG1506	peptidase
NDY25_04230	COG1297	OPT oligopeptide transporter protein
NDY25_04300	COG2080	2 iron, 2 sulfur cluster binding
NDY25_04305	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
NDY25_04310	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NDY25_04320	COG1064	alcohol dehydrogenase
NDY25_04370	COG3537	Alpha-1,2-mannosidase
NDY25_04380	COG1028	Short-chain dehydrogenase reductase Sdr
NDY25_04390	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NDY25_04560	COG0308	aminopeptidase N
NDY25_04575	COG0330	HflC and HflK could
NDY25_04580	COG0330	HflC and HflK could
NDY25_04600	COG0678	peroxiredoxin activity
NDY25_04610	COG4953	penicillin-binding protein 1C
NDY25_04640	COG2373	Large extracellular alpha-helical protein
NDY25_04675	COG3829	transcription factor binding
NDY25_04685	COG2161	toxin-antitoxin pair type II binding
NDY25_04690	COG4115	mRNA cleavage
NDY25_04710	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NDY25_04715	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NDY25_04735	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NDY25_04745	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NDY25_04750	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NDY25_04755	COG1399	metal-binding, possibly nucleic acid-binding protein
NDY25_04760	COG0424	maF-like protein
NDY25_04775	COG0714	Associated with various cellular activities
NDY25_04795	COG0537	adenosine 5'-monophosphoramidase activity
NDY25_04805	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NDY25_04910	COG0314	molybdopterin synthase activity
NDY25_04915	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NDY25_04920	COG0315	cyclic pyranopterin monophosphate synthase activity
NDY25_04925	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NDY25_04940	COG0859	PFAM glycosyl transferase family 9
NDY25_04955	COG0631	protein serine/threonine phosphatase activity
NDY25_04975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NDY25_04985	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NDY25_05015	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NDY25_05025	COG0544	peptidyl-prolyl cis-trans isomerase activity
NDY25_05070	COG0473	3-isopropylmalate dehydrogenase activity
NDY25_05085	COG4783	chaperone-mediated protein folding
NDY25_05090	COG0745	RESPONSE REGULATOR receiver
NDY25_05100	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NDY25_05110	COG0438	transferase activity, transferring glycosyl groups
NDY25_05115	COG0671	phosphoesterase, PA-phosphatase related
NDY25_05120	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NDY25_05130	COG3291	Pkd domain containing protein
NDY25_05135	COG2833	Protein of unknown function (DUF455)
NDY25_05155	COG0285	dihydrofolate synthase activity
NDY25_05165	COG0406	alpha-ribazole phosphatase activity
NDY25_05195	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NDY25_05200	COG4208	sulfate ABC transporter
NDY25_05205	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
NDY25_05210	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
NDY25_05215	COG0156	8-amino-7-oxononanoate synthase activity
NDY25_05235	COG2885	chlorophyll binding
NDY25_05240	COG0604	alcohol dehydrogenase
NDY25_05245	COG0446	pyridine nucleotide-disulphide oxidoreductase
NDY25_05245	COG1902	pentaerythritol trinitrate reductase activity
NDY25_05265	COG0625	glutathione transferase activity
NDY25_05275	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NDY25_05280	COG1217	gtp-binding protein TYPA
NDY25_05290	COG0154	amidase activity
NDY25_05300	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
NDY25_05310	COG0203	ribosomal protein L17
NDY25_05335	COG0201	protein transport
NDY25_05380	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NDY25_05390	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NDY25_05395	COG0255	Belongs to the universal ribosomal protein uL29 family
NDY25_05410	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NDY25_05420	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NDY25_05440	COG0051	transcription antitermination factor activity, RNA binding
NDY25_05445	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NDY25_05460	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NDY25_05465	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NDY25_05475	COG0222	ribosome binding
NDY25_05480	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NDY25_05485	COG0081	regulation of translation
NDY25_05490	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NDY25_05495	COG0250	Participates in transcription elongation, termination and antitermination
NDY25_05500	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NDY25_05530	COG0012	GTP binding
NDY25_05535	COG0193	aminoacyl-tRNA hydrolase activity
NDY25_05540	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NDY25_05545	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NDY25_05560	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
NDY25_05570	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NDY25_05585	COG0521	Mo-molybdopterin cofactor biosynthetic process
NDY25_05605	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NDY25_05610	COG1295	ribonuclease BN
NDY25_05635	COG1404	Belongs to the peptidase S8 family
NDY25_05640	COG1404	Belongs to the peptidase S8 family
NDY25_05645	COG1404	Belongs to the peptidase S8 family
NDY25_05650	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NDY25_05700	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NDY25_05700	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NDY25_05720	COG2890	protein-(glutamine-N5) methyltransferase activity
NDY25_05730	COG3634	alkyl hydroperoxide reductase activity
NDY25_05740	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NDY25_05745	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NDY25_05755	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NDY25_05765	COG2197	response regulator
NDY25_05795	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NDY25_05800	COG0697	spore germination
NDY25_05830	COG3386	PFAM SMP-30 Gluconolaconase
NDY25_05850	COG1024	Enoyl-CoA hydratase
NDY25_05860	COG0318	PFAM AMP-dependent synthetase and ligase
NDY25_05865	COG0583	DNA-binding transcription factor activity
NDY25_05870	COG3384	dioxygenase
NDY25_05900	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NDY25_05905	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NDY25_05915	COG2096	Adenosyltransferase
NDY25_05920	COG0123	including yeast histone deacetylase and acetoin utilization protein
NDY25_05935	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NDY25_05940	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NDY25_05945	COG2967	ApaG domain
NDY25_05950	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NDY25_05955	COG0431	NADPH-dependent FMN reductase
NDY25_05960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NDY25_05970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NDY25_05975	COG1116	anion transmembrane transporter activity
NDY25_05995	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NDY25_06015	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NDY25_06025	COG0642	Histidine kinase
NDY25_06040	COG4181	ATPase activity
NDY25_06050	COG2175	clavaminate synthase activity
NDY25_06060	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
NDY25_06065	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NDY25_06085	COG4771	TonB-dependent receptor
NDY25_06095	COG0667	Aldo Keto reductase
NDY25_06100	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NDY25_06110	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NDY25_06115	COG4106	trans-aconitate 2-methyltransferase activity
NDY25_06125	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NDY25_06155	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NDY25_06170	COG2357	RelA SpoT domain protein
NDY25_06205	COG0604	alcohol dehydrogenase
NDY25_06205	COG1028	Short-chain dehydrogenase reductase Sdr
NDY25_06205	COG3321	synthase
NDY25_06215	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NDY25_06230	COG0494	nUDIX hydrolase
NDY25_06240	COG0653	protein targeting
NDY25_06245	COG0739	heme binding
NDY25_06270	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NDY25_06275	COG1181	Belongs to the D-alanine--D-alanine ligase family
NDY25_06280	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NDY25_06300	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NDY25_06305	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NDY25_06315	COG3116	cell division
NDY25_06360	COG0792	nuclease activity
NDY25_06365	COG1988	membrane-bound metal-dependent
NDY25_06370	COG0277	FAD linked oxidase domain protein
NDY25_06375	COG0823	Involved in the tonB-independent uptake of proteins
NDY25_06375	COG4946	Tricorn protease homolog
NDY25_06375	COG1506	peptidase
NDY25_06380	COG0745	RESPONSE REGULATOR receiver
NDY25_06385	COG2205	protein histidine kinase activity
NDY25_06395	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NDY25_06400	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NDY25_06415	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NDY25_06450	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NDY25_06450	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NDY25_06465	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NDY25_06475	COG0488	(ABC) transporter
NDY25_06480	COG0242	peptide deformylase activity
NDY25_06495	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NDY25_06540	COG2188	Transcriptional regulator
NDY25_06555	COG1450	Type ii and iii secretion system protein
NDY25_06570	COG3166	PFAM Fimbrial assembly family protein
NDY25_06575	COG3156	type II secretion system protein K
NDY25_06580	COG4795	General secretion pathway protein
NDY25_06585	COG2165	general secretion pathway protein
NDY25_06590	COG4970	Tfp pilus assembly protein FimT
NDY25_06595	COG2165	general secretion pathway protein
NDY25_06600	COG1459	type II secretion system
NDY25_06605	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NDY25_06615	COG5295	Hep Hag repeat protein
NDY25_06620	COG1404	Belongs to the peptidase S8 family
NDY25_06635	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NDY25_06635	COG0047	phosphoribosylformylglycinamidine synthase activity
NDY25_06640	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NDY25_06645	COG4974	Belongs to the 'phage' integrase family
NDY25_06655	COG0795	lipopolysaccharide-transporting ATPase activity
NDY25_06675	COG0525	valine-tRNA ligase activity
NDY25_06710	COG1183	phosphatidylcholine synthase activity
NDY25_06725	COG0442	prolyl-tRNA aminoacylation
NDY25_06740	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NDY25_06745	COG1127	ABC transporter
NDY25_06750	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NDY25_06750	COG3218	ABC-type transport auxiliary lipoprotein component
NDY25_06780	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NDY25_06790	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NDY25_06795	COG0662	Cupin 2, conserved barrel domain protein
NDY25_06795	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
NDY25_06820	COG2086	electron transfer activity
NDY25_06835	COG0463	Glycosyl transferase, family 2
NDY25_06855	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NDY25_06860	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
NDY25_06930	COG0625	glutathione transferase activity
NDY25_06940	COG0513	Belongs to the DEAD box helicase family
NDY25_06950	COG4771	TonB-dependent receptor
NDY25_06955	COG0720	synthase
NDY25_06965	COG1569	PIN domain
NDY25_06970	COG3311	Transcriptional regulator
NDY25_06975	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NDY25_06980	COG1956	GAF domain-containing protein
NDY25_06990	COG2819	hydrolase of the alpha beta superfamily
NDY25_07000	COG0546	phosphoglycolate phosphatase activity
NDY25_07010	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NDY25_07025	COG0339	signal peptide processing
NDY25_07040	COG2132	Multicopper oxidase
NDY25_07075	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NDY25_07085	COG1136	(ABC) transporter
NDY25_07095	COG1136	(ABC) transporter
NDY25_07095	COG0577	efflux transmembrane transporter activity
NDY25_07105	COG4191	Histidine kinase
NDY25_07115	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NDY25_07130	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NDY25_07155	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NDY25_07165	COG0356	it plays a direct role in the translocation of protons across the membrane
NDY25_07185	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NDY25_07195	COG0508	dehydrogenase complex catalyzes the overall conversion of
NDY25_07230	COG2011	ABC-type metal ion transport system permease component
NDY25_07235	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NDY25_07240	COG0697	spore germination
NDY25_07245	COG1666	GTP binding
NDY25_07260	COG1187	pseudouridine synthase activity
NDY25_07265	COG2813	Specifically methylates the guanine in position
NDY25_07285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NDY25_07285	COG0784	Response regulator, receiver
NDY25_07285	COG2198	Histidine kinase
NDY25_07285	COG2205	protein histidine kinase activity
NDY25_07305	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NDY25_07310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NDY25_07365	COG0842	Transport permease protein
NDY25_07370	COG1131	(ABC) transporter
NDY25_07375	COG0025	NhaP-type Na H and K H
NDY25_07385	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
NDY25_07390	COG1573	uracil-dna glycosylase
NDY25_07400	COG3384	dioxygenase
NDY25_07410	COG0583	DNA-binding transcription factor activity
NDY25_07420	COG0667	Aldo Keto reductase
NDY25_07430	COG3590	peptidase
NDY25_07445	COG0531	amino acid
NDY25_07460	COG2972	Histidine kinase
NDY25_07480	COG3685	Protein conserved in bacteria
NDY25_07485	COG3546	catalase activity
NDY25_07510	COG2204	response regulator
NDY25_07525	COG1028	Short-chain dehydrogenase reductase Sdr
NDY25_07530	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NDY25_07550	COG1132	(ABC) transporter
NDY25_07560	COG1063	alcohol dehydrogenase
NDY25_07585	COG0583	DNA-binding transcription factor activity
NDY25_07590	COG2814	Major facilitator Superfamily
NDY25_07630	COG1131	(ABC) transporter
NDY25_07645	COG0251	oxidation-reduction process
NDY25_07665	COG0840	transmembrane signaling receptor activity
NDY25_07695	COG0024	Methionine aminopeptidase
NDY25_07725	COG1309	transcriptional regulator
NDY25_07735	COG1902	pentaerythritol trinitrate reductase activity
NDY25_07765	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NDY25_07820	COG3039	Transposase
NDY25_07840	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NDY25_07845	COG1490	D-aminoacyl-tRNA deacylase activity
NDY25_07850	COG1560	Kdo2-lipid A biosynthetic process
NDY25_07860	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NDY25_07895	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NDY25_07895	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NDY25_07900	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NDY25_07905	COG0242	peptide deformylase activity
NDY25_07910	COG1652	LysM domain
NDY25_07915	COG0758	DNA mediated transformation
NDY25_07935	COG1754	DNA topoisomerase type I activity
NDY25_07935	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NDY25_07955	COG1028	Short-chain dehydrogenase reductase Sdr
NDY25_07965	COG0616	signal peptide processing
NDY25_07970	COG0534	Mate efflux family protein
NDY25_07985	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NDY25_07995	COG0625	glutathione transferase activity
NDY25_08010	COG1252	NADH dehydrogenase
NDY25_08015	COG2860	membrane
NDY25_08020	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NDY25_08025	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NDY25_08030	COG2201	protein-glutamate methylesterase activity
NDY25_08035	COG2177	Part of the ABC transporter FtsEX involved in
NDY25_08040	COG2884	Cell division ATP-binding protein ftsE
NDY25_08050	COG3118	belongs to the thioredoxin family
NDY25_08055	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NDY25_08090	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
NDY25_08120	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NDY25_08120	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NDY25_08125	COG1473	amidohydrolase
NDY25_08130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NDY25_08135	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NDY25_08145	COG5383	Protein conserved in bacteria
NDY25_08185	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
NDY25_08205	COG3023	N-Acetylmuramoyl-L-alanine amidase
NDY25_08215	COG4948	Mandelate Racemase Muconate Lactonizing
NDY25_08225	COG0531	amino acid
NDY25_08240	COG4682	membrane
NDY25_08245	COG2133	pyrroloquinoline quinone binding
NDY25_08260	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NDY25_08275	COG1610	YqeY-like protein
NDY25_08280	COG1295	ribonuclease BN
NDY25_08300	COG0109	protoheme IX farnesyltransferase activity
NDY25_08330	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
NDY25_08345	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NDY25_08390	COG0739	heme binding
NDY25_08405	COG2807	transmembrane transport
NDY25_08410	COG0708	Exodeoxyribonuclease III
NDY25_08425	COG1192	Involved in chromosome partitioning
NDY25_08430	COG1475	DNA binding
NDY25_08445	COG0463	Glycosyl transferase, family 2
NDY25_08465	COG0756	dUTP diphosphatase activity
NDY25_08470	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NDY25_08480	COG0018	arginyl-trna synthetase
NDY25_08490	COG4221	oxidoreductase activity
NDY25_08515	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NDY25_08520	COG1166	arginine decarboxylase activity
NDY25_08525	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NDY25_08560	COG0606	chelatase, subunit chli
NDY25_08575	COG4943	cyclic-guanylate-specific phosphodiesterase activity
NDY25_08625	COG1090	epimerase
NDY25_08655	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NDY25_08680	COG1011	Hydrolase
NDY25_08685	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NDY25_08715	COG2197	response regulator
NDY25_08720	COG4585	Histidine kinase
NDY25_08725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NDY25_08730	COG1136	(ABC) transporter
NDY25_08735	COG3039	Transposase
NDY25_08760	COG0697	spore germination
NDY25_08785	COG0180	Tryptophanyl-tRNA synthetase
NDY25_08790	COG3237	CsbD-like
NDY25_08830	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NDY25_08845	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NDY25_08850	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
NDY25_08850	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
NDY25_08860	COG3228	Belongs to the MtfA family
NDY25_08890	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NDY25_08910	COG1199	ATP-dependent helicase activity
NDY25_08935	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NDY25_08990	COG2801	Transposase and inactivated derivatives
NDY25_09040	COG0625	glutathione transferase activity
NDY25_09075	COG4555	ABC transporter
NDY25_09085	COG1476	TRANSCRIPTIONal
NDY25_09110	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NDY25_09115	COG1131	(ABC) transporter
NDY25_09120	COG0842	Transport permease protein
NDY25_09140	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NDY25_09165	COG1607	acyl-coa hydrolase
NDY25_09170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NDY25_09190	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NDY25_09195	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NDY25_09205	COG0045	succinate-CoA ligase (ADP-forming) activity
NDY25_09205	COG1042	CoA-binding domain protein
NDY25_09205	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NDY25_09220	COG1629	transport
NDY25_09220	COG4771	TonB-dependent receptor
NDY25_09225	COG2239	Acts as a magnesium transporter
NDY25_09235	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NDY25_09240	COG3387	PFAM Glycoside hydrolase 15-related
NDY25_09250	COG3100	YcgL domain-containing protein
NDY25_09255	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NDY25_09275	COG1028	Short-chain dehydrogenase reductase Sdr
NDY25_09320	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NDY25_09400	COG3621	Patatin-like phospholipase
NDY25_09420	COG0210	DNA helicase
NDY25_09430	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NDY25_09440	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NDY25_09450	COG2159	amidohydrolase
NDY25_09475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NDY25_09500	COG3540	Alkaline phosphatase
NDY25_09510	COG2091	lysine biosynthetic process via aminoadipic acid
NDY25_09525	COG0708	Exodeoxyribonuclease III
NDY25_09545	COG1940	carbohydrate kinase activity
NDY25_09570	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NDY25_09575	COG3162	membrane
NDY25_09625	COG1028	Short-chain dehydrogenase reductase Sdr
NDY25_09630	COG0179	Fumarylacetoacetate (FAA) hydrolase
NDY25_09635	COG4948	Mandelate Racemase Muconate Lactonizing
NDY25_09640	COG3254	rhamnose metabolic process
NDY25_09645	COG0738	Major facilitator superfamily
NDY25_09650	COG1414	Transcriptional regulator
NDY25_09665	COG1971	Probably functions as a manganese efflux pump
NDY25_09670	COG2205	protein histidine kinase activity
NDY25_09675	COG3459	Glycosyltransferase 36 associated
NDY25_09680	COG2211	Major facilitator Superfamily
NDY25_09685	COG3265	gluconokinase activity
NDY25_09690	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NDY25_09715	COG2911	Protein conserved in bacteria
NDY25_09720	COG0729	surface antigen
NDY25_09725	COG4771	TonB-dependent receptor
NDY25_09730	COG0457	Tetratricopeptide repeat
NDY25_09745	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NDY25_09760	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NDY25_09760	COG0519	Catalyzes the synthesis of GMP from XMP
NDY25_09770	COG0805	protein transport
NDY25_09775	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NDY25_09780	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NDY25_09790	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NDY25_09805	COG2974	May be involved in recombination
NDY25_09810	COG0037	tRNA processing
NDY25_09815	COG2115	Belongs to the xylose isomerase family
NDY25_09825	COG3661	Belongs to the glycosyl hydrolase 67 family
NDY25_09835	COG4948	Mandelate Racemase Muconate Lactonizing
NDY25_09845	COG1472	Belongs to the glycosyl hydrolase 3 family
NDY25_09850	COG0246	Mannitol dehydrogenase
NDY25_09880	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NDY25_09885	COG1620	l-lactate permease
NDY25_09900	COG3386	PFAM SMP-30 Gluconolaconase
NDY25_09910	COG3250	beta-galactosidase activity
NDY25_09915	COG1904	glucuronate isomerase
NDY25_09920	COG3693	PFAM glycoside hydrolase, family 10
NDY25_09935	COG2211	Major facilitator Superfamily
NDY25_09970	COG2937	Belongs to the GPAT DAPAT family
NDY25_10000	COG0284	orotidine-5'-phosphate decarboxylase activity
NDY25_10005	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
NDY25_10010	COG3132	Protein of unknown function, DUF480
NDY25_10030	COG0210	DNA helicase
NDY25_10035	COG1435	thymidine kinase activity
NDY25_10045	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
NDY25_10055	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NDY25_10085	COG3135	benzoate transporter
NDY25_10105	COG0676	glucose-6-phosphate 1-epimerase activity
NDY25_10120	COG0730	response to heat
NDY25_10155	COG0302	gtp cyclohydrolase
NDY25_10170	COG1566	PFAM secretion protein HlyD family protein
NDY25_10180	COG1289	transmembrane transporter activity
NDY25_10185	COG0477	Major facilitator Superfamily
NDY25_10195	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NDY25_10270	COG2801	Transposase and inactivated derivatives
NDY25_10310	COG2207	Transcriptional regulator
NDY25_10315	COG1028	Short-chain dehydrogenase reductase Sdr
NDY25_10325	COG3549	Plasmid maintenance system killer
NDY25_10340	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NDY25_10345	COG1074	ATP-dependent DNA helicase activity
NDY25_10350	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
NDY25_10385	COG1127	ABC transporter
NDY25_10390	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NDY25_10395	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NDY25_10410	COG2853	Lipoprotein
NDY25_10430	COG0386	Belongs to the glutathione peroxidase family
NDY25_10440	COG1322	Protein conserved in bacteria
NDY25_10445	COG0625	glutathione transferase activity
NDY25_10450	COG0531	amino acid
NDY25_10455	COG3537	Alpha-1,2-mannosidase
NDY25_10475	COG2203	Gaf domain
NDY25_10475	COG2199	diguanylate cyclase activity
NDY25_10480	COG3835	regulator
NDY25_10485	COG1929	Belongs to the glycerate kinase type-1 family
NDY25_10490	COG2271	Major facilitator Superfamily
NDY25_10540	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NDY25_10545	COG0861	Integral membrane protein TerC family
NDY25_10555	COG0584	glycerophosphoryl diester phosphodiesterase
NDY25_10570	COG0671	phosphoesterase, PA-phosphatase related
NDY25_10580	COG3293	Transposase
NDY25_10595	COG0706	membrane insertase activity
NDY25_10625	COG0187	DNA topoisomerase II activity
NDY25_10635	COG0501	Belongs to the peptidase M48B family
NDY25_10670	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
NDY25_10680	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NDY25_10715	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NDY25_10720	COG0793	Belongs to the peptidase S41A family
NDY25_10725	COG4942	peptidase
NDY25_10735	COG2234	aminopeptidase activity
NDY25_10750	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NDY25_10755	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NDY25_10760	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NDY25_10765	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NDY25_10770	COG1064	alcohol dehydrogenase
NDY25_10780	COG0493	'glutamate synthase
NDY25_10785	COG0067	glutamate synthase
NDY25_10785	COG0069	glutamate synthase activity
NDY25_10785	COG0070	glutamate synthase
NDY25_10820	COG1741	Belongs to the pirin family
NDY25_10830	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NDY25_10845	COG3459	Glycosyltransferase 36 associated
NDY25_10850	COG3459	Glycosyltransferase 36 associated
NDY25_10860	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NDY25_10910	COG1111	helicase
NDY25_10910	COG1205	dead DEAH box helicase
NDY25_10915	COG3177	Filamentation induced by cAMP protein fic
NDY25_10920	COG1272	protein, Hemolysin III
NDY25_10950	COG0583	DNA-binding transcription factor activity
NDY25_10955	COG1028	Short-chain dehydrogenase reductase Sdr
NDY25_10965	COG1733	regulation of RNA biosynthetic process
NDY25_11080	COG1484	DNA-dependent DNA replication
NDY25_11085	COG4584	PFAM Integrase catalytic
NDY25_11115	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NDY25_11125	COG3237	CsbD-like
NDY25_11165	COG0657	acetylesterase activity
NDY25_11175	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NDY25_11220	COG0714	Associated with various cellular activities
NDY25_11280	COG4772	TonB-dependent receptor
NDY25_11290	COG0662	Cupin 2, conserved barrel domain protein
NDY25_11300	COG1012	belongs to the aldehyde dehydrogenase family
NDY25_11365	COG1755	Isoprenylcysteine carboxyl methyltransferase
NDY25_11370	COG4585	Histidine kinase
NDY25_11375	COG2197	response regulator
NDY25_11390	COG3710	Transcriptional regulator
NDY25_11410	COG4771	TonB-dependent receptor
NDY25_11610	COG0366	Alpha amylase catalytic
NDY25_11615	COG0366	Alpha amylase catalytic
NDY25_11620	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NDY25_11650	COG2755	lipolytic protein G-D-S-L family
NDY25_11660	COG0657	acetylesterase activity
NDY25_11660	COG2755	lipolytic protein G-D-S-L family
NDY25_11670	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
NDY25_11685	COG3507	Belongs to the glycosyl hydrolase 43 family
NDY25_11690	COG1609	Transcriptional regulator
NDY25_11695	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NDY25_11700	COG1028	Short-chain dehydrogenase reductase Sdr
NDY25_11710	COG2755	lipolytic protein G-D-S-L family
NDY25_11735	COG3186	Phenylalanine-4-hydroxylase
NDY25_11740	COG1522	sequence-specific DNA binding
NDY25_11750	COG1752	Esterase of the alpha-beta hydrolase superfamily
NDY25_11755	COG1119	ATPase activity
NDY25_11770	COG0517	IMP dehydrogenase activity
NDY25_11770	COG1125	glycine betaine transport
NDY25_11785	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NDY25_11795	COG3550	peptidyl-serine autophosphorylation
NDY25_11800	COG1396	sequence-specific DNA binding
NDY25_11820	COG0489	protein tyrosine kinase activity
NDY25_11825	COG2062	phosphohistidine phosphatase, SixA
NDY25_11835	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NDY25_11855	COG3039	Transposase
NDY25_11865	COG1881	PFAM PEBP family protein
NDY25_11880	COG0174	glutamine synthetase
NDY25_11885	COG0347	Belongs to the P(II) protein family
NDY25_11890	COG0004	ammonium transporteR
NDY25_11895	COG3852	Histidine kinase
NDY25_11900	COG2204	response regulator
NDY25_11905	COG2032	superoxide dismutase activity
NDY25_11910	COG2032	superoxide dismutase activity
NDY25_11920	COG0183	Belongs to the thiolase family
NDY25_11960	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NDY25_11970	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NDY25_11980	COG0028	Belongs to the TPP enzyme family
NDY25_12010	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NDY25_12025	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NDY25_12030	COG3177	Filamentation induced by cAMP protein fic
NDY25_12035	COG0596	Alpha beta hydrolase
NDY25_12040	COG0727	PFAM Uncharacterised protein family (UPF0153)
NDY25_12045	COG0318	PFAM AMP-dependent synthetase and ligase
NDY25_12060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NDY25_12075	COG1181	Belongs to the D-alanine--D-alanine ligase family
NDY25_12090	COG0564	pseudouridine synthase activity
NDY25_12110	COG1446	asparaginase
NDY25_12145	COG0475	glutathione-regulated potassium exporter activity
NDY25_12150	COG0583	DNA-binding transcription factor activity
NDY25_12155	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NDY25_12160	COG2224	Isocitrate lyase
NDY25_12195	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NDY25_12200	COG1960	acyl-CoA dehydrogenase activity
NDY25_12255	COG0523	cobalamin synthesis protein
NDY25_12270	COG0697	spore germination
NDY25_12280	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
NDY25_12295	COG1846	Transcriptional regulator
NDY25_12300	COG1764	response to oxidative stress
NDY25_12325	COG0656	L-ascorbic acid biosynthetic process
NDY25_12330	COG2130	NADP-dependent
NDY25_12345	COG1187	pseudouridine synthase activity
NDY25_12355	COG1643	Atp-dependent helicase
NDY25_12360	COG0840	transmembrane signaling receptor activity
NDY25_12365	COG4807	Protein conserved in bacteria
NDY25_12370	COG2351	hydroxyisourate hydrolase activity
NDY25_12375	COG2072	flavoprotein involved in K transport
NDY25_12395	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NDY25_12450	COG3039	Transposase
NDY25_12455	COG3039	Transposase
NDY25_12495	COG2252	PERMEase
NDY25_12515	COG0084	hydrolase, TatD family'
NDY25_12525	COG0583	DNA-binding transcription factor activity
NDY25_12530	COG2814	Major facilitator Superfamily
NDY25_12540	COG0596	Alpha beta hydrolase
NDY25_12560	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NDY25_12565	COG1902	pentaerythritol trinitrate reductase activity
NDY25_12585	COG2223	nitrite transmembrane transporter activity
NDY25_12590	COG0745	RESPONSE REGULATOR receiver
NDY25_12595	COG2205	protein histidine kinase activity
NDY25_12600	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NDY25_12620	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NDY25_12625	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NDY25_12655	COG0702	epimerase
NDY25_12660	COG1733	regulation of RNA biosynthetic process
NDY25_12755	COG3039	Transposase
NDY25_12790	COG0129	dihydroxy-acid dehydratase activity
NDY25_12800	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NDY25_12850	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NDY25_12855	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NDY25_12890	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NDY25_12895	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NDY25_12905	COG3485	protocatechuate 3,4-dioxygenase
NDY25_12910	COG3485	protocatechuate 3,4-dioxygenase
NDY25_12920	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NDY25_12925	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NDY25_12935	COG1414	Transcriptional regulator
NDY25_12945	COG0657	acetylesterase activity
NDY25_12955	COG0445	tRNA wobble uridine modification
NDY25_12965	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NDY25_13005	COG0156	8-amino-7-oxononanoate synthase activity
NDY25_13010	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NDY25_13015	COG1040	competence protein
NDY25_13045	COG1511	domain protein
NDY25_13045	COG3264	Mechanosensitive ion channel
NDY25_13055	COG1368	sulfuric ester hydrolase activity
NDY25_13060	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NDY25_13065	COG2354	Protein conserved in bacteria
NDY25_13070	COG1649	PFAM Uncharacterised BCR, COG1649
NDY25_13080	COG0297	glycogen (starch) synthase activity
NDY25_13085	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NDY25_13090	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NDY25_13115	COG0702	epimerase
NDY25_13130	COG1028	Short-chain dehydrogenase reductase Sdr
NDY25_13165	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NDY25_13175	COG0513	Belongs to the DEAD box helicase family
NDY25_13185	COG0508	dehydrogenase complex catalyzes the overall conversion of
NDY25_13200	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NDY25_13215	COG3104	oligopeptide transport
NDY25_13235	COG2852	Protein conserved in bacteria
NDY25_13245	COG3039	Transposase
NDY25_13280	COG1320	monovalent cation:proton antiporter activity
NDY25_13285	COG2212	antiporter activity
NDY25_13295	COG0651	ATP synthesis coupled electron transport
NDY25_13300	COG1006	Multisubunit Na H antiporter MnhC subunit
NDY25_13360	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NDY25_13370	COG1597	lipid kinase activity
NDY25_13395	COG2963	transposase activity
NDY25_13430	COG3039	Transposase
NDY25_13440	COG3039	Transposase
NDY25_13450	COG3039	Transposase
NDY25_13535	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NDY25_13605	COG0840	transmembrane signaling receptor activity
NDY25_13620	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NDY25_13625	COG0134	indole-3-glycerol-phosphate synthase activity
NDY25_13635	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NDY25_13650	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
NDY25_13715	COG0316	Belongs to the HesB IscA family
NDY25_13720	COG2816	NAD+ diphosphatase activity
NDY25_13725	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
NDY25_13745	COG2814	Major facilitator Superfamily
NDY25_13750	COG1289	transmembrane transporter activity
NDY25_13755	COG0151	Belongs to the GarS family
NDY25_13760	COG0138	bifunctional purine biosynthesis protein purh
NDY25_13790	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
NDY25_13810	COG2264	protein methyltransferase activity
NDY25_13825	COG0439	Biotin carboxylase
NDY25_13835	COG0511	ligase activity, forming carbon-carbon bonds
NDY25_13840	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NDY25_13860	COG1324	tolerance protein
NDY25_13865	COG2356	endonuclease I
NDY25_13880	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NDY25_13895	COG2189	Belongs to the N(4) N(6)-methyltransferase family
NDY25_13930	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NDY25_13955	COG3712	iron ion homeostasis
NDY25_13980	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
NDY25_13995	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NDY25_14020	COG2353	YceI-like domain
NDY25_14045	COG3052	prosthetic group binding
NDY25_14080	COG1802	Transcriptional regulator
NDY25_14095	COG1366	Belongs to the anti-sigma-factor antagonist family
NDY25_14150	COG2801	Transposase and inactivated derivatives
NDY25_14230	COG3039	Transposase
NDY25_14240	COG3039	Transposase
NDY25_14260	COG4206	TonB-dependent receptor
NDY25_14265	COG0823	Involved in the tonB-independent uptake of proteins
NDY25_14265	COG1506	peptidase
NDY25_14310	COG0435	Glutathione S-transferase
NDY25_14345	COG0823	Involved in the tonB-independent uptake of proteins
NDY25_14345	COG1506	peptidase
NDY25_14380	COG0697	spore germination
NDY25_14395	COG4305	rare lipoprotein A
NDY25_14400	COG1113	amino acid transport
NDY25_14415	COG3507	Belongs to the glycosyl hydrolase 43 family
NDY25_14460	COG0840	transmembrane signaling receptor activity
NDY25_14470	COG0659	secondary active sulfate transmembrane transporter activity
NDY25_14500	COG3275	phosphorelay sensor kinase activity
NDY25_14510	COG0181	hydroxymethylbilane synthase activity
NDY25_14535	COG1505	serine-type exopeptidase activity
NDY25_14540	COG0436	Aminotransferase
NDY25_14550	COG2832	Protein of unknown function (DUF454)
NDY25_14560	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NDY25_14570	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
NDY25_14575	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NDY25_14580	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NDY25_14585	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NDY25_14610	COG2226	methyltransferase
NDY25_14615	COG5001	Diguanylate cyclase
NDY25_14615	COG3300	MHYT domain
NDY25_14620	COG0308	aminopeptidase N
NDY25_14655	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
NDY25_14675	COG0730	response to heat
NDY25_14680	COG1012	belongs to the aldehyde dehydrogenase family
NDY25_14685	COG0367	asparagine synthase
NDY25_14690	COG1213	nucleotidyl transferase
NDY25_14700	COG0028	Belongs to the TPP enzyme family
NDY25_14700	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
NDY25_14715	COG3284	Transcriptional regulator
NDY25_14720	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NDY25_14725	COG1077	Cell shape determining protein MreB Mrl
NDY25_14730	COG1792	Involved in formation and maintenance of cell shape
NDY25_14735	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
NDY25_14745	COG0772	Belongs to the SEDS family
NDY25_14770	COG2951	lytic endotransglycosylase activity
NDY25_14775	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NDY25_14780	COG1686	Belongs to the peptidase S11 family
NDY25_14800	COG0321	lipoyl(octanoyl) transferase activity
NDY25_14805	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NDY25_14820	COG1051	belongs to the nudix hydrolase family
NDY25_14820	COG1056	cytidyltransferase-related domain
NDY25_14855	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
NDY25_14860	COG0673	inositol 2-dehydrogenase activity
NDY25_14865	COG2823	Periplasmic or secreted lipoprotein
NDY25_14890	COG4251	negative regulation of phosphorylation
NDY25_14895	COG0784	Response regulator, receiver
NDY25_14900	COG4191	Histidine kinase
NDY25_14905	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NDY25_14910	COG1028	Short-chain dehydrogenase reductase Sdr
NDY25_14955	COG1459	type II secretion system
NDY25_14980	COG3156	type II secretion system protein K
NDY25_15005	COG3250	beta-galactosidase activity
NDY25_15020	COG2188	Transcriptional regulator
NDY25_15030	COG1609	Transcriptional regulator
NDY25_15035	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NDY25_15040	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NDY25_15080	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
NDY25_15090	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NDY25_15100	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NDY25_15115	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NDY25_15120	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
NDY25_15135	COG2205	protein histidine kinase activity
NDY25_15155	COG3920	Histidine kinase
NDY25_15170	COG3791	Glutathione-dependent formaldehyde-activating
NDY25_15180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NDY25_15190	COG0697	spore germination
NDY25_15230	COG0402	S-adenosylhomocysteine deaminase activity
NDY25_15245	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NDY25_15250	COG0726	polysaccharide deacetylase
NDY25_15255	COG4773	Receptor
NDY25_15275	COG0436	Aminotransferase
NDY25_15315	COG2211	Major facilitator Superfamily
NDY25_15320	COG1609	Transcriptional regulator
NDY25_15325	COG1028	Short-chain dehydrogenase reductase Sdr
NDY25_15330	COG2851	Citrate transporter
NDY25_15345	COG0642	Histidine kinase
NDY25_15355	COG2197	response regulator
NDY25_15365	COG0583	DNA-binding transcription factor activity
NDY25_15385	COG4191	Histidine kinase
NDY25_15400	COG0280	phosphate acetyltransferase
NDY25_15400	COG0281	malic enzyme
NDY25_15425	COG1560	Kdo2-lipid A biosynthetic process
NDY25_15430	COG1519	Transferase
NDY25_15435	COG1538	Outer membrane efflux protein
NDY25_15440	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NDY25_15460	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NDY25_15465	COG0066	3-isopropylmalate dehydratase activity
NDY25_15470	COG2226	methyltransferase
NDY25_15475	COG0473	3-isopropylmalate dehydrogenase activity
NDY25_15480	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NDY25_15500	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NDY25_15505	COG0405	Gamma-glutamyltransferase
NDY25_15510	COG0840	transmembrane signaling receptor activity
NDY25_15520	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NDY25_15525	COG3710	Transcriptional regulator
NDY25_15545	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NDY25_15555	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
NDY25_15570	COG0563	adenylate kinase activity
NDY25_15575	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NDY25_15585	COG3781	membrane
NDY25_15590	COG0671	phosphoesterase, PA-phosphatase related
NDY25_15605	COG1028	Short-chain dehydrogenase reductase Sdr
NDY25_15620	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NDY25_15625	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NDY25_15655	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NDY25_15660	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
NDY25_15670	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NDY25_15680	COG0352	thiamine-phosphate diphosphorylase activity
NDY25_15685	COG1773	rubredoxin
NDY25_15690	COG2912	Transglutaminase-like superfamily
NDY25_15710	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NDY25_15735	COG0006	proline dipeptidase activity
NDY25_15745	COG0006	proline dipeptidase activity
NDY25_15760	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NDY25_15765	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NDY25_15770	COG0346	lactoylglutathione lyase activity
NDY25_15775	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NDY25_15780	COG1561	YicC-like family, N-terminal region
NDY25_15795	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NDY25_15805	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NDY25_15830	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
NDY25_15860	COG0714	Associated with various cellular activities
NDY25_15890	COG1301	dicarboxylic acid transport
NDY25_15905	COG4773	Receptor
NDY25_15910	COG0583	DNA-binding transcription factor activity
NDY25_15915	COG1028	Short-chain dehydrogenase reductase Sdr
NDY25_15925	COG1376	ErfK ybiS ycfS ynhG family protein
NDY25_15960	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
NDY25_15965	COG4149	molybdate abc transporter
NDY25_15970	COG0725	ABC transporter, periplasmic molybdate-binding protein
NDY25_15975	COG3453	Protein conserved in bacteria
NDY25_15975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NDY25_15985	COG3047	cAMP biosynthetic process
NDY25_16000	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NDY25_16030	COG0469	pyruvate kinase activity
NDY25_16035	COG3588	fructose-bisphosphate aldolase
NDY25_16040	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
NDY25_16055	COG1648	precorrin-2 dehydrogenase activity
NDY25_16055	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NDY25_16070	COG0784	Response regulator, receiver
NDY25_16070	COG2198	Histidine kinase
NDY25_16070	COG2205	protein histidine kinase activity
NDY25_16090	COG0175	sulfate reduction
NDY25_16095	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NDY25_16100	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NDY25_16110	COG2895	sulfate adenylyltransferase (ATP) activity
NDY25_16110	COG0529	Catalyzes the synthesis of activated sulfate
NDY25_16115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NDY25_16120	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NDY25_16145	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NDY25_16170	COG3039	Transposase
NDY25_16200	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NDY25_16205	COG2272	Belongs to the type-B carboxylesterase lipase family
NDY25_16220	COG4948	Mandelate Racemase Muconate Lactonizing
NDY25_16225	COG3250	beta-galactosidase activity
NDY25_16235	COG1609	Transcriptional regulator
NDY25_16265	COG0471	metal ion transport
NDY25_16265	COG3273	potassium ion transport
NDY25_16270	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NDY25_16320	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NDY25_16355	COG2801	Transposase and inactivated derivatives
NDY25_16360	COG3220	belongs to the UPF0276 family
NDY25_16415	COG3039	Transposase
NDY25_16550	COG2814	Major facilitator Superfamily
NDY25_16570	COG3039	Transposase
NDY25_16610	COG2856	Zn peptidase
NDY25_16625	COG0583	DNA-binding transcription factor activity
NDY25_16630	COG1238	metal cluster binding
NDY25_16635	COG0840	transmembrane signaling receptor activity
NDY25_16670	COG0189	ligase activity
NDY25_16675	COG0745	RESPONSE REGULATOR receiver
NDY25_16705	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NDY25_16715	COG4969	Belongs to the N-Me-Phe pilin family
NDY25_16725	COG2194	sulfuric ester hydrolase activity
NDY25_16770	COG0045	succinate-CoA ligase (ADP-forming) activity
NDY25_16775	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NDY25_16805	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NDY25_16805	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NDY25_16815	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NDY25_16820	COG0564	pseudouridine synthase activity
NDY25_16835	COG3011	Protein conserved in bacteria
NDY25_16840	COG0840	transmembrane signaling receptor activity
NDY25_16855	COG3387	PFAM Glycoside hydrolase 15-related
NDY25_16860	COG1877	trehalose-phosphatase activity
NDY25_16905	COG4771	TonB-dependent receptor
NDY25_16915	COG0667	Aldo Keto reductase
NDY25_16920	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NDY25_16925	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NDY25_16930	COG1116	anion transmembrane transporter activity
NDY25_16935	COG0542	response to heat
NDY25_16945	COG4206	TonB-dependent receptor
NDY25_16950	COG1492	cobalamin metabolic process
NDY25_16960	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
NDY25_16975	COG5297	Belongs to the glycosyl hydrolase family 6
NDY25_16980	COG5599	Phosphatase
NDY25_16990	COG0019	diaminopimelate decarboxylase activity
NDY25_16995	COG4264	IucA IucC family
NDY25_17000	COG2814	Major facilitator Superfamily
NDY25_17005	COG4264	IucA IucC family
NDY25_17015	COG4772	TonB-dependent receptor
NDY25_17025	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NDY25_17025	COG4651	solute:proton antiporter activity
NDY25_17050	COG0488	(ABC) transporter
NDY25_17065	COG0477	Major facilitator Superfamily
NDY25_17120	COG2255	four-way junction helicase activity
NDY25_17125	COG0824	Thioesterase
NDY25_17135	COG0848	biopolymer transport protein
NDY25_17150	COG2885	chlorophyll binding
NDY25_17160	COG0602	queuosine metabolic process
NDY25_17165	COG0667	Aldo Keto reductase
NDY25_17175	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NDY25_17180	COG3920	Histidine kinase
NDY25_17200	COG0840	transmembrane signaling receptor activity
NDY25_17210	COG1187	pseudouridine synthase activity
NDY25_17225	COG0514	ATP-dependent DNA helicase (RecQ)
NDY25_17230	COG0783	Belongs to the Dps family
NDY25_17235	COG1643	Atp-dependent helicase
NDY25_17245	COG0837	glucose binding
NDY25_17255	COG0535	radical SAM domain protein
NDY25_17270	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NDY25_17280	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NDY25_17290	COG1216	Glycosyl transferase, family 2
NDY25_17295	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NDY25_17305	COG1199	ATP-dependent helicase activity
NDY25_17320	COG0189	ligase activity
NDY25_17335	COG0835	chemotaxis
NDY25_17340	COG0840	transmembrane signaling receptor activity
NDY25_17345	COG0643	Histidine kinase
NDY25_17345	COG0784	Response regulator, receiver
NDY25_17345	COG2198	Histidine kinase
NDY25_17350	COG2201	protein-glutamate methylesterase activity
NDY25_17375	COG1595	DNA-templated transcription, initiation
NDY25_17385	COG1446	asparaginase
NDY25_17415	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
NDY25_17420	COG0732	type I restriction modification DNA specificity domain
NDY25_17435	COG3645	SOS response
NDY25_17480	COG3537	Alpha-1,2-mannosidase
NDY25_17490	COG1486	melibiose metabolic process
NDY25_17505	COG0531	amino acid
NDY25_17535	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NDY25_17540	COG1388	LysM domain
NDY25_17540	COG3858	chitin binding
NDY25_17555	COG0837	glucose binding
NDY25_17560	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NDY25_17570	COG0494	nUDIX hydrolase
NDY25_17575	COG1218	3'(2'),5'-bisphosphate nucleotidase
NDY25_17580	COG3956	TIGRFAM MazG family protein
NDY25_17585	COG1742	UPF0060 membrane protein
NDY25_17590	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NDY25_17595	COG0509	glycine decarboxylation via glycine cleavage system
NDY25_17620	COG1960	acyl-CoA dehydrogenase activity
NDY25_17630	COG1309	transcriptional regulator
NDY25_17645	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NDY25_17655	COG0463	Glycosyl transferase, family 2
NDY25_17660	COG0517	IMP dehydrogenase activity
NDY25_17660	COG0516	GMP reductase activity
NDY25_17670	COG2982	Protein involved in outer membrane biogenesis
NDY25_17675	COG1272	protein, Hemolysin III
NDY25_17680	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NDY25_17690	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NDY25_17695	COG0626	cystathionine gamma-synthase activity
NDY25_17700	COG0527	aspartate kinase activity
NDY25_17700	COG0460	homoserine dehydrogenase
NDY25_17710	COG1760	l-serine dehydratase
NDY25_17720	COG1278	Cold shock
NDY25_17730	COG3038	cytochrome b561
NDY25_17735	COG2353	YceI-like domain
NDY25_17740	COG2205	protein histidine kinase activity
NDY25_17740	COG2198	Histidine kinase
NDY25_17740	COG0784	Response regulator, receiver
NDY25_17755	COG0477	Major facilitator Superfamily
NDY25_17760	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NDY25_17770	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NDY25_17775	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NDY25_17780	COG0259	pyridoxamine-phosphate oxidase activity
NDY25_17795	COG1842	Phage shock protein A
NDY25_17820	COG0754	glutathionylspermidine amidase activity
NDY25_17830	COG0789	Transcriptional regulator
NDY25_17880	COG0531	amino acid
NDY25_17885	COG2197	response regulator
NDY25_17900	COG1113	amino acid transport
NDY25_17910	COG1271	oxidase subunit
NDY25_17915	COG1294	oxidase, subunit
NDY25_17925	COG2239	Acts as a magnesium transporter
NDY25_17930	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NDY25_17935	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NDY25_17955	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NDY25_17970	COG1137	ATPase activity
NDY25_17975	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
NDY25_17985	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
NDY25_18000	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NDY25_18020	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NDY25_18040	COG0628	permease
NDY25_18080	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NDY25_18085	COG0084	hydrolase, TatD family'
NDY25_18100	COG1960	acyl-CoA dehydrogenase activity
NDY25_18115	COG0367	asparagine synthase
NDY25_18125	COG0305	Participates in initiation and elongation during chromosome replication
NDY25_18130	COG0415	Belongs to the DNA photolyase family
NDY25_18140	COG0583	DNA-binding transcription factor activity
NDY25_18155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NDY25_18185	COG3706	GGDEF domain
NDY25_18260	COG3039	Transposase
NDY25_18290	COG0556	nucleotide-excision repair
NDY25_18305	COG3505	Type IV secretory pathway VirD4
NDY25_18325	COG2948	multi-organism process
NDY25_18345	COG3702	type iv secretory pathway
NDY25_18360	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NDY25_18365	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NDY25_18380	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NDY25_18385	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NDY25_18385	COG0072	phenylalanine-tRNA ligase activity
NDY25_18435	COG0438	transferase activity, transferring glycosyl groups
NDY25_18440	COG0438	transferase activity, transferring glycosyl groups
NDY25_18450	COG0438	transferase activity, transferring glycosyl groups
NDY25_18475	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NDY25_18480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NDY25_18485	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NDY25_18505	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NDY25_18515	COG1960	acyl-CoA dehydrogenase activity
NDY25_18525	COG3040	lipid binding
NDY25_18545	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NDY25_18555	COG4191	Histidine kinase
NDY25_18555	COG0784	Response regulator, receiver
NDY25_18565	COG1194	a g-specific adenine glycosylase
NDY25_18580	COG3938	Belongs to the proline racemase family
NDY25_18585	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NDY25_18600	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NDY25_18610	COG0006	proline dipeptidase activity
NDY25_18625	COG0531	amino acid
NDY25_18700	COG0742	ribosomal rna small subunit methyltransferase
NDY25_18715	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NDY25_18730	COG3291	Pkd domain containing protein
NDY25_18770	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NDY25_18775	COG0343	queuine tRNA-ribosyltransferase activity
NDY25_18780	COG1862	Preprotein translocase
NDY25_18790	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NDY25_18840	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NDY25_18840	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NDY25_18845	COG1105	Belongs to the carbohydrate kinase PfkB family
NDY25_18850	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NDY25_18850	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NDY25_18855	COG1609	Transcriptional regulator
NDY25_18860	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NDY25_18875	COG2902	Dehydrogenase
NDY25_18880	COG0604	alcohol dehydrogenase
NDY25_18880	COG3321	synthase
NDY25_18890	COG1902	pentaerythritol trinitrate reductase activity
NDY25_18900	COG0300	oxidoreductase activity
NDY25_18905	COG0604	alcohol dehydrogenase
NDY25_18915	COG0477	Major facilitator Superfamily
NDY25_18925	COG0784	Response regulator, receiver
NDY25_18925	COG5002	protein histidine kinase activity
NDY25_18925	COG2205	protein histidine kinase activity
NDY25_18930	COG2733	membrane
NDY25_18945	COG1121	(ABC) transporter
NDY25_18955	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NDY25_18960	COG2223	nitrite transmembrane transporter activity
NDY25_18970	COG0243	molybdopterin cofactor binding
NDY25_18980	COG0477	Major facilitator Superfamily
NDY25_18990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NDY25_18995	COG0174	glutamine synthetase
NDY25_19000	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NDY25_19035	COG3842	ATPase activity
NDY25_19045	COG1176	ABC-type spermidine putrescine transport system, permease component I
NDY25_19050	COG1177	transmembrane transport
NDY25_19060	COG1012	belongs to the aldehyde dehydrogenase family
NDY25_19075	COG4535	Mg2 and Co2 transporter CorC
NDY25_19085	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NDY25_19095	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NDY25_19110	COG0741	lytic transglycosylase activity
NDY25_19115	COG0723	plastoquinol--plastocyanin reductase activity
NDY25_19120	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NDY25_19125	COG2857	Cytochrome c1
NDY25_19130	COG0625	glutathione transferase activity
NDY25_19135	COG2969	positive regulation of protein catabolic process
NDY25_19145	COG1201	RNA secondary structure unwinding
NDY25_19155	COG0840	transmembrane signaling receptor activity
NDY25_19160	COG0835	chemotaxis
NDY25_19165	COG2199	diguanylate cyclase activity
NDY25_19195	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NDY25_19210	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NDY25_19215	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NDY25_19215	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NDY25_19230	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NDY25_19250	COG1028	Short-chain dehydrogenase reductase Sdr
NDY25_19255	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NDY25_19260	COG0501	Belongs to the peptidase M48B family
NDY25_19265	COG3300	MHYT domain
NDY25_19265	COG5001	Diguanylate cyclase
NDY25_19270	COG2081	HI0933 family
NDY25_19275	COG4681	YaeQ
NDY25_19280	COG1671	Belongs to the UPF0178 family
NDY25_19290	COG0625	glutathione transferase activity
NDY25_19300	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
NDY25_19310	COG0513	Belongs to the DEAD box helicase family
NDY25_19315	COG0488	(ABC) transporter
NDY25_19330	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NDY25_19335	COG0483	inositol monophosphate 1-phosphatase activity
NDY25_19350	COG3300	MHYT domain
NDY25_19350	COG5001	Diguanylate cyclase
NDY25_19370	COG0402	S-adenosylhomocysteine deaminase activity
NDY25_19375	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NDY25_19435	COG4302	ethanolamine ammonia-lyase activity
NDY25_19440	COG4303	Ethanolamine ammonia lyase large subunit
NDY25_19455	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NDY25_19475	COG2166	iron-sulfur cluster assembly
NDY25_19480	COG0215	cysteine-tRNA ligase activity
NDY25_19490	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NDY25_19495	COG0137	argininosuccinate synthase activity
NDY25_19500	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NDY25_19505	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NDY25_19520	COG0165	Argininosuccinate lyase
NDY25_19535	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NDY25_19565	COG1294	oxidase, subunit
NDY25_19575	COG4988	ABC transporter
NDY25_19580	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NDY25_19620	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
NDY25_19645	COG0436	Aminotransferase
NDY25_19650	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NDY25_19665	COG1187	pseudouridine synthase activity
NDY25_19670	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NDY25_19675	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NDY25_19680	COG2350	Protein conserved in bacteria
NDY25_19705	COG1653	transport
NDY25_19710	COG1175	transmembrane transport
NDY25_19715	COG0395	ABC-type sugar transport system, permease component
NDY25_19740	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NDY25_19745	COG2957	Belongs to the agmatine deiminase family
NDY25_19760	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NDY25_19780	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
NDY25_19785	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NDY25_19795	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NDY25_19800	COG0475	glutathione-regulated potassium exporter activity
NDY25_19800	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NDY25_19810	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NDY25_19825	COG0582	viral genome integration into host DNA
NDY25_19885	COG3039	Transposase
NDY25_19955	COG0840	transmembrane signaling receptor activity
NDY25_19975	COG2205	protein histidine kinase activity
NDY25_19975	COG5002	protein histidine kinase activity
NDY25_19975	COG0784	Response regulator, receiver
NDY25_19980	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
NDY25_19985	COG4191	Histidine kinase
NDY25_19985	COG0784	Response regulator, receiver
NDY25_20000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NDY25_20010	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
NDY25_20020	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NDY25_20085	COG2244	polysaccharide biosynthetic process
NDY25_20115	COG2264	protein methyltransferase activity
NDY25_20120	COG0297	glycogen (starch) synthase activity
NDY25_20125	COG0438	transferase activity, transferring glycosyl groups
NDY25_20140	COG1136	(ABC) transporter
NDY25_20145	COG1132	(ABC) transporter
NDY25_20150	COG0477	Major facilitator Superfamily
NDY25_20155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NDY25_20170	COG1253	flavin adenine dinucleotide binding
NDY25_20205	COG0504	CTP synthase activity
NDY25_20220	COG0148	phosphopyruvate hydratase activity
NDY25_20225	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NDY25_20230	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NDY25_20235	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NDY25_20245	COG2840	Smr protein MutS2
NDY25_20250	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NDY25_20255	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NDY25_20260	COG1238	metal cluster binding
NDY25_20275	COG1534	Rna-binding protein
NDY25_20280	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
NDY25_20290	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NDY25_20295	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NDY25_20305	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NDY25_20310	COG1546	Belongs to the CinA family
NDY25_20315	COG4771	TonB-dependent receptor
NDY25_20320	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NDY25_20330	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NDY25_20335	COG2137	regulation of response to DNA damage stimulus
NDY25_20340	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NDY25_20345	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NDY25_20360	COG1741	Belongs to the pirin family
NDY25_20365	COG0583	DNA-binding transcription factor activity
NDY25_20385	COG0352	thiamine-phosphate diphosphorylase activity
NDY25_20385	COG0351	phosphomethylpyrimidine kinase
NDY25_20400	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NDY25_20405	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NDY25_20420	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NDY25_20430	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
NDY25_20445	COG4948	Mandelate Racemase Muconate Lactonizing
NDY25_20450	COG0800	Aldolase
NDY25_20485	COG1501	Belongs to the glycosyl hydrolase 31 family
NDY25_20495	COG1070	Carbohydrate kinase
NDY25_20500	COG2115	Belongs to the xylose isomerase family
NDY25_20505	COG0477	Major facilitator Superfamily
NDY25_20525	COG0860	N-Acetylmuramoyl-L-alanine amidase
NDY25_20550	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NDY25_20555	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NDY25_20585	COG1472	Belongs to the glycosyl hydrolase 3 family
NDY25_20595	COG2203	Gaf domain
NDY25_20595	COG3706	GGDEF domain
NDY25_20595	COG4251	negative regulation of phosphorylation
NDY25_20595	COG5001	Diguanylate cyclase
NDY25_20600	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NDY25_20605	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
NDY25_20615	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NDY25_20620	COG0671	phosphoesterase, PA-phosphatase related
NDY25_20640	COG0697	spore germination
NDY25_20645	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NDY25_20650	COG0167	dihydroorotate dehydrogenase activity
NDY25_20665	COG1012	belongs to the aldehyde dehydrogenase family
NDY25_20675	COG3209	COG3209 Rhs family protein
NDY25_20700	COG3039	Transposase
NDY25_20715	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
NDY25_20720	COG0460	homoserine dehydrogenase
NDY25_20720	COG0527	aspartate kinase activity
NDY25_20750	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NDY25_20765	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NDY25_20770	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NDY25_20775	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NDY25_20780	COG0131	Imidazoleglycerol-phosphate dehydratase
NDY25_20780	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
NDY25_20790	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NDY25_20795	COG0107	imidazoleglycerol-phosphate synthase activity
NDY25_20800	COG0140	phosphoribosyl-ATP diphosphatase activity
NDY25_20800	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NDY25_20815	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
NDY25_20830	COG0531	amino acid
NDY25_20835	COG0531	amino acid
NDY25_20845	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NDY25_20850	COG0277	FAD linked oxidase domain protein
NDY25_20870	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NDY25_20885	COG1024	Enoyl-CoA hydratase
NDY25_20905	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NDY25_20915	COG0505	Belongs to the CarA family
NDY25_20925	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NDY25_20930	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NDY25_20940	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NDY25_20965	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NDY25_20975	COG2205	protein histidine kinase activity
NDY25_20975	COG2198	Histidine kinase
NDY25_20975	COG0784	Response regulator, receiver
NDY25_20980	COG2205	protein histidine kinase activity
NDY25_20980	COG2198	Histidine kinase
NDY25_20980	COG0784	Response regulator, receiver
NDY25_20985	COG1024	Enoyl-CoA hydratase
NDY25_20990	COG0318	PFAM AMP-dependent synthetase and ligase
NDY25_21035	COG2201	protein-glutamate methylesterase activity
NDY25_21050	COG0840	transmembrane signaling receptor activity
NDY25_21060	COG0835	chemotaxis
NDY25_21070	COG0840	transmembrane signaling receptor activity
NDY25_21075	COG0840	transmembrane signaling receptor activity
NDY25_21090	COG0840	transmembrane signaling receptor activity
NDY25_21095	COG0840	transmembrane signaling receptor activity
NDY25_21100	COG0840	transmembrane signaling receptor activity
NDY25_21105	COG0840	transmembrane signaling receptor activity
NDY25_21105	COG0840	transmembrane signaling receptor activity
NDY25_21115	COG0840	transmembrane signaling receptor activity
NDY25_21125	COG2198	Histidine kinase
NDY25_21125	COG0643	Histidine kinase
NDY25_21130	COG0745	RESPONSE REGULATOR receiver
NDY25_21140	COG0835	chemotaxis
NDY25_21145	COG1192	Involved in chromosome partitioning
NDY25_21155	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NDY25_21180	COG4771	TonB-dependent receptor
NDY25_21210	COG1169	isochorismate synthase
NDY25_21240	COG2226	methyltransferase
NDY25_21240	COG3433	isochorismatase activity
NDY25_21240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NDY25_21245	COG3321	synthase
NDY25_21245	COG0604	alcohol dehydrogenase
NDY25_21260	COG2226	methyltransferase
NDY25_21260	COG3433	isochorismatase activity
NDY25_21260	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NDY25_21275	COG4771	TonB-dependent receptor
NDY25_21285	COG2375	cellular response to nickel ion
NDY25_21285	COG1132	(ABC) transporter
NDY25_21290	COG1132	(ABC) transporter
NDY25_21295	COG1132	(ABC) transporter
NDY25_21300	COG2198	Histidine kinase
NDY25_21300	COG0784	Response regulator, receiver
NDY25_21300	COG0643	Histidine kinase
NDY25_21350	COG3300	MHYT domain
NDY25_21350	COG5001	Diguanylate cyclase
NDY25_21370	COG3190	flagellar
NDY25_21420	COG1677	Flagellar hook-basal body complex protein FliE
NDY25_21440	COG3039	Transposase
NDY25_21470	COG1028	Short-chain dehydrogenase reductase Sdr
NDY25_21475	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NDY25_21495	COG2201	protein-glutamate methylesterase activity
NDY25_21525	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NDY25_21530	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NDY25_21545	COG1705	Flagellar rod assembly protein muramidase FlgJ
NDY25_21545	COG3951	Flagellar rod assembly protein muramidase FlgJ
NDY25_21565	COG4787	bacterial-type flagellum-dependent cell motility
NDY25_21575	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
NDY25_21580	COG1558	bacterial-type flagellum-dependent cell motility
NDY25_21590	COG0784	Response regulator, receiver
NDY25_21590	COG0835	chemotaxis
NDY25_21610	COG4191	Histidine kinase
NDY25_21650	COG0482	sulfurtransferase activity
NDY25_21665	COG0542	response to heat
NDY25_21675	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
NDY25_21685	COG0492	ferredoxin-NADP+ reductase activity
NDY25_21690	COG1674	ftsk spoiiie
NDY25_21705	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NDY25_21710	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NDY25_21715	COG0183	Belongs to the thiolase family
NDY25_21720	COG1250	3-hydroxyacyl-CoA dehydrogenase
NDY25_21720	COG1024	Enoyl-CoA hydratase
NDY25_21735	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NDY25_21745	COG1426	Protein conserved in bacteria
NDY25_21755	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NDY25_21760	COG1160	GTP binding
NDY25_21765	COG0303	'Molybdopterin
NDY25_21770	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NDY25_21780	COG0708	Exodeoxyribonuclease III
NDY25_21790	COG0303	'Molybdopterin
NDY25_21795	COG0746	molybdenum cofactor guanylyltransferase activity
NDY25_21805	COG1648	precorrin-2 dehydrogenase activity
NDY25_21805	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NDY25_21815	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NDY25_21820	COG2223	nitrite transmembrane transporter activity
NDY25_21825	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NDY25_21835	COG0243	molybdopterin cofactor binding
NDY25_21855	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
NDY25_21865	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NDY25_21875	COG0579	oxidoreductase
NDY25_21895	COG3685	Protein conserved in bacteria
NDY25_21910	COG5001	Diguanylate cyclase
NDY25_21930	COG2205	protein histidine kinase activity
NDY25_21945	COG3713	MltA-interacting MipA family protein
NDY25_21985	COG4191	Histidine kinase
NDY25_21985	COG0784	Response regulator, receiver
NDY25_22020	COG3781	membrane
NDY25_22025	COG4191	Histidine kinase
NDY25_22030	COG2197	response regulator
NDY25_22060	COG0840	transmembrane signaling receptor activity
NDY25_22105	COG0488	(ABC) transporter
NDY25_22400	COG0551	DNA topoisomerase type I activity
NDY25_22400	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NDY25_22455	COG3846	protein secretion by the type IV secretion system
NDY25_22470	COG3451	type IV secretory pathway VirB4
NDY25_22475	COG3451	type IV secretory pathway VirB4
NDY25_22495	COG4644	lycopene metabolic process
NDY25_22550	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NDY25_22565	COG0653	protein targeting
NDY25_22780	COG4962	Type ii secretion system protein e