locus-tag	class	description
N8D55_00030	COG3135	benzoate transporter
N8D55_00065	COG0730	response to heat
N8D55_00135	COG0477	Major facilitator Superfamily
N8D55_00220	COG2801	Transposase and inactivated derivatives
N8D55_00225	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
N8D55_00260	COG2207	Transcriptional regulator
N8D55_00265	COG1028	Short-chain dehydrogenase reductase Sdr
N8D55_00290	COG1074	ATP-dependent DNA helicase activity
N8D55_00330	COG1127	ABC transporter
N8D55_00335	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
N8D55_00340	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
N8D55_00355	COG2853	Lipoprotein
N8D55_00380	COG0386	Belongs to the glutathione peroxidase family
N8D55_00390	COG1322	Protein conserved in bacteria
N8D55_00395	COG0625	glutathione transferase activity
N8D55_00400	COG0531	amino acid
N8D55_00425	COG2203	Gaf domain
N8D55_00425	COG2199	diguanylate cyclase activity
N8D55_00430	COG3835	regulator
N8D55_00435	COG1929	Belongs to the glycerate kinase type-1 family
N8D55_00495	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
N8D55_00500	COG0861	Integral membrane protein TerC family
N8D55_00510	COG0584	glycerophosphoryl diester phosphodiesterase
N8D55_00540	COG3293	Transposase
N8D55_00555	COG0706	membrane insertase activity
N8D55_00585	COG0187	DNA topoisomerase II activity
N8D55_00595	COG0501	Belongs to the peptidase M48B family
N8D55_00630	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
N8D55_00640	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
N8D55_00675	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
N8D55_00680	COG0793	Belongs to the peptidase S41A family
N8D55_00695	COG2234	aminopeptidase activity
N8D55_00720	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
N8D55_00745	COG0493	'glutamate synthase
N8D55_00750	COG0067	glutamate synthase
N8D55_00750	COG0069	glutamate synthase activity
N8D55_00750	COG0070	glutamate synthase
N8D55_00790	COG1741	Belongs to the pirin family
N8D55_00820	COG3459	Glycosyltransferase 36 associated
N8D55_00830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N8D55_00880	COG1111	helicase
N8D55_00880	COG1205	dead DEAH box helicase
N8D55_00885	COG3177	Filamentation induced by cAMP protein fic
N8D55_00920	COG0583	DNA-binding transcription factor activity
N8D55_00925	COG1028	Short-chain dehydrogenase reductase Sdr
N8D55_00935	COG1733	regulation of RNA biosynthetic process
N8D55_00970	COG2801	Transposase and inactivated derivatives
N8D55_01060	COG1484	DNA-dependent DNA replication
N8D55_01065	COG4584	PFAM Integrase catalytic
N8D55_01070	COG4584	PFAM Integrase catalytic
N8D55_01100	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
N8D55_01110	COG3237	CsbD-like
N8D55_01160	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N8D55_01205	COG0714	Associated with various cellular activities
N8D55_01265	COG4772	TonB-dependent receptor
N8D55_01275	COG0662	Cupin 2, conserved barrel domain protein
N8D55_01285	COG1012	belongs to the aldehyde dehydrogenase family
N8D55_01290	COG1028	Short-chain dehydrogenase reductase Sdr
N8D55_01350	COG1755	Isoprenylcysteine carboxyl methyltransferase
N8D55_01355	COG4585	Histidine kinase
N8D55_01360	COG2197	response regulator
N8D55_01385	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
N8D55_01625	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
N8D55_01655	COG2755	lipolytic protein G-D-S-L family
N8D55_01665	COG2755	lipolytic protein G-D-S-L family
N8D55_01665	COG0657	acetylesterase activity
N8D55_01675	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
N8D55_01690	COG3507	Belongs to the glycosyl hydrolase 43 family
N8D55_01705	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
N8D55_01710	COG1028	Short-chain dehydrogenase reductase Sdr
N8D55_01720	COG2755	lipolytic protein G-D-S-L family
N8D55_01760	COG1752	Esterase of the alpha-beta hydrolase superfamily
N8D55_01765	COG1119	ATPase activity
N8D55_01795	COG1262	PFAM Formylglycine-generating sulfatase enzyme
N8D55_01805	COG3550	peptidyl-serine autophosphorylation
N8D55_01810	COG1396	sequence-specific DNA binding
N8D55_01830	COG0489	protein tyrosine kinase activity
N8D55_01835	COG2062	phosphohistidine phosphatase, SixA
N8D55_01845	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
N8D55_01865	COG3039	Transposase
N8D55_01890	COG0174	glutamine synthetase
N8D55_01895	COG0347	Belongs to the P(II) protein family
N8D55_01900	COG0004	ammonium transporteR
N8D55_01920	COG2032	superoxide dismutase activity
N8D55_01980	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
N8D55_01990	COG0028	Belongs to the TPP enzyme family
N8D55_02020	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
N8D55_02035	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
N8D55_02040	COG3177	Filamentation induced by cAMP protein fic
N8D55_02050	COG0727	PFAM Uncharacterised protein family (UPF0153)
N8D55_02055	COG0318	PFAM AMP-dependent synthetase and ligase
N8D55_02070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N8D55_02085	COG1181	Belongs to the D-alanine--D-alanine ligase family
N8D55_02100	COG0564	pseudouridine synthase activity
N8D55_02120	COG1446	asparaginase
N8D55_02155	COG0475	glutathione-regulated potassium exporter activity
N8D55_02160	COG0583	DNA-binding transcription factor activity
N8D55_02265	COG0523	cobalamin synthesis protein
N8D55_02305	COG1846	Transcriptional regulator
N8D55_02310	COG1764	response to oxidative stress
N8D55_02335	COG0656	L-ascorbic acid biosynthetic process
N8D55_02340	COG2130	NADP-dependent
N8D55_02355	COG1187	pseudouridine synthase activity
N8D55_02370	COG0840	transmembrane signaling receptor activity
N8D55_02375	COG4807	Protein conserved in bacteria
N8D55_02380	COG2351	hydroxyisourate hydrolase activity
N8D55_02385	COG2072	flavoprotein involved in K transport
N8D55_02465	COG3039	Transposase
N8D55_02525	COG0084	hydrolase, TatD family'
N8D55_02535	COG0583	DNA-binding transcription factor activity
N8D55_02550	COG0596	Alpha beta hydrolase
N8D55_02570	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
N8D55_02600	COG0745	RESPONSE REGULATOR receiver
N8D55_02610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N8D55_02630	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
N8D55_02635	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
N8D55_02640	COG0583	DNA-binding transcription factor activity
N8D55_02665	COG0702	epimerase
N8D55_02670	COG1733	regulation of RNA biosynthetic process
N8D55_02770	COG3039	Transposase
N8D55_02780	COG2801	Transposase and inactivated derivatives
N8D55_02800	COG0129	dihydroxy-acid dehydratase activity
N8D55_02810	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
N8D55_02860	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
N8D55_02865	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
N8D55_02905	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
N8D55_02910	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
N8D55_02920	COG3485	protocatechuate 3,4-dioxygenase
N8D55_02925	COG3485	protocatechuate 3,4-dioxygenase
N8D55_02930	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
N8D55_02935	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
N8D55_02940	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
N8D55_02950	COG1414	Transcriptional regulator
N8D55_02960	COG0657	acetylesterase activity
N8D55_02970	COG0445	tRNA wobble uridine modification
N8D55_02980	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
N8D55_03025	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
N8D55_03030	COG1040	competence protein
N8D55_03060	COG3264	Mechanosensitive ion channel
N8D55_03060	COG1511	domain protein
N8D55_03070	COG1368	sulfuric ester hydrolase activity
N8D55_03095	COG0297	glycogen (starch) synthase activity
N8D55_03100	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
N8D55_03105	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
N8D55_03130	COG0702	epimerase
N8D55_03145	COG1028	Short-chain dehydrogenase reductase Sdr
N8D55_03180	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
N8D55_03200	COG0508	dehydrogenase complex catalyzes the overall conversion of
N8D55_03235	COG3104	oligopeptide transport
N8D55_03255	COG2852	Protein conserved in bacteria
N8D55_03300	COG1320	monovalent cation:proton antiporter activity
N8D55_03305	COG2212	antiporter activity
N8D55_03315	COG0651	ATP synthesis coupled electron transport
N8D55_03320	COG1006	Multisubunit Na H antiporter MnhC subunit
N8D55_03380	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
N8D55_03390	COG1597	lipid kinase activity
N8D55_03445	COG3039	Transposase
N8D55_03645	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
N8D55_03650	COG0134	indole-3-glycerol-phosphate synthase activity
N8D55_03660	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N8D55_03675	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
N8D55_03740	COG0316	Belongs to the HesB IscA family
N8D55_03745	COG2816	NAD+ diphosphatase activity
N8D55_03770	COG2814	Major facilitator Superfamily
N8D55_03775	COG1289	transmembrane transporter activity
N8D55_03780	COG0151	Belongs to the GarS family
N8D55_03815	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
N8D55_03835	COG2264	protein methyltransferase activity
N8D55_03850	COG0439	Biotin carboxylase
N8D55_03860	COG0511	ligase activity, forming carbon-carbon bonds
N8D55_03865	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
N8D55_03885	COG1324	tolerance protein
N8D55_03905	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
N8D55_03915	COG2189	Belongs to the N(4) N(6)-methyltransferase family
N8D55_03955	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
N8D55_03985	COG3712	iron ion homeostasis
N8D55_03990	COG3712	iron ion homeostasis
N8D55_04020	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
N8D55_04035	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
N8D55_04060	COG2353	YceI-like domain
N8D55_04080	COG3052	prosthetic group binding
N8D55_04130	COG1366	Belongs to the anti-sigma-factor antagonist family
N8D55_04195	COG2801	Transposase and inactivated derivatives
N8D55_04300	COG4206	TonB-dependent receptor
N8D55_04305	COG0823	Involved in the tonB-independent uptake of proteins
N8D55_04305	COG1506	peptidase
N8D55_04350	COG0435	Glutathione S-transferase
N8D55_04385	COG1506	peptidase
N8D55_04385	COG0823	Involved in the tonB-independent uptake of proteins
N8D55_04430	COG0697	spore germination
N8D55_04450	COG1113	amino acid transport
N8D55_04465	COG3507	Belongs to the glycosyl hydrolase 43 family
N8D55_04510	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
N8D55_04510	COG5297	Belongs to the glycosyl hydrolase family 6
N8D55_04515	COG0659	secondary active sulfate transmembrane transporter activity
N8D55_04550	COG3275	phosphorelay sensor kinase activity
N8D55_04560	COG0181	hydroxymethylbilane synthase activity
N8D55_04590	COG0436	Aminotransferase
N8D55_04600	COG2832	Protein of unknown function (DUF454)
N8D55_04625	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
N8D55_04630	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
N8D55_04635	COG0355	proton-transporting ATP synthase activity, rotational mechanism
N8D55_04660	COG2226	methyltransferase
N8D55_04665	COG3300	MHYT domain
N8D55_04665	COG5001	Diguanylate cyclase
N8D55_04730	COG0730	response to heat
N8D55_04735	COG1012	belongs to the aldehyde dehydrogenase family
N8D55_04740	COG0367	asparagine synthase
N8D55_04745	COG1213	nucleotidyl transferase
N8D55_04755	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
N8D55_04755	COG0028	Belongs to the TPP enzyme family
N8D55_04770	COG3284	Transcriptional regulator
N8D55_04775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N8D55_04780	COG1077	Cell shape determining protein MreB Mrl
N8D55_04790	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
N8D55_04835	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
N8D55_04840	COG1686	Belongs to the peptidase S11 family
N8D55_04860	COG0321	lipoyl(octanoyl) transferase activity
N8D55_04865	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
N8D55_04915	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
N8D55_04920	COG0673	inositol 2-dehydrogenase activity
N8D55_04925	COG2823	Periplasmic or secreted lipoprotein
N8D55_04960	COG0784	Response regulator, receiver
N8D55_04965	COG4191	Histidine kinase
N8D55_04975	COG1028	Short-chain dehydrogenase reductase Sdr
N8D55_05020	COG1459	type II secretion system
N8D55_05045	COG3156	type II secretion system protein K
N8D55_05090	COG2188	Transcriptional regulator
N8D55_05110	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
N8D55_05145	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
N8D55_05165	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
N8D55_05180	COG0218	Necessary for normal cell division and for the maintenance of normal septation
N8D55_05185	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
N8D55_05220	COG3920	Histidine kinase
N8D55_05245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N8D55_05255	COG0697	spore germination
N8D55_05265	COG1307	EDD domain protein, DegV family
N8D55_05295	COG0402	S-adenosylhomocysteine deaminase activity
N8D55_05310	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
N8D55_05320	COG4773	Receptor
N8D55_05325	COG4773	Receptor
N8D55_05345	COG0436	Aminotransferase
N8D55_05390	COG1609	Transcriptional regulator
N8D55_05395	COG1028	Short-chain dehydrogenase reductase Sdr
N8D55_05400	COG2851	Citrate transporter
N8D55_05415	COG0642	Histidine kinase
N8D55_05425	COG2197	response regulator
N8D55_05440	COG0583	DNA-binding transcription factor activity
N8D55_05460	COG4191	Histidine kinase
N8D55_05475	COG0281	malic enzyme
N8D55_05475	COG0280	phosphate acetyltransferase
N8D55_05500	COG1560	Kdo2-lipid A biosynthetic process
N8D55_05505	COG1519	Transferase
N8D55_05510	COG1538	Outer membrane efflux protein
N8D55_05540	COG0066	3-isopropylmalate dehydratase activity
N8D55_05545	COG2226	methyltransferase
N8D55_05550	COG0473	3-isopropylmalate dehydrogenase activity
N8D55_05555	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
N8D55_05575	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
N8D55_05580	COG0405	Gamma-glutamyltransferase
N8D55_05585	COG0840	transmembrane signaling receptor activity
N8D55_05595	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
N8D55_05600	COG3710	Transcriptional regulator
N8D55_05630	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
N8D55_05645	COG0563	adenylate kinase activity
N8D55_05660	COG3781	membrane
N8D55_05665	COG0671	phosphoesterase, PA-phosphatase related
N8D55_05745	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
N8D55_05755	COG0352	thiamine-phosphate diphosphorylase activity
N8D55_05760	COG1773	rubredoxin
N8D55_05765	COG2912	Transglutaminase-like superfamily
N8D55_05785	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
N8D55_05810	COG0006	proline dipeptidase activity
N8D55_05840	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
N8D55_05845	COG0346	lactoylglutathione lyase activity
N8D55_05850	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
N8D55_05855	COG1561	YicC-like family, N-terminal region
N8D55_05980	COG4773	Receptor
N8D55_05985	COG0583	DNA-binding transcription factor activity
N8D55_05990	COG1028	Short-chain dehydrogenase reductase Sdr
N8D55_06000	COG1376	ErfK ybiS ycfS ynhG family protein
N8D55_06035	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
N8D55_06040	COG4149	molybdate abc transporter
N8D55_06045	COG0725	ABC transporter, periplasmic molybdate-binding protein
N8D55_06060	COG3047	cAMP biosynthetic process
N8D55_06075	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
N8D55_06110	COG0469	pyruvate kinase activity
N8D55_06115	COG3588	fructose-bisphosphate aldolase
N8D55_06120	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
N8D55_06135	COG1648	precorrin-2 dehydrogenase activity
N8D55_06135	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
N8D55_06155	COG2205	protein histidine kinase activity
N8D55_06155	COG2198	Histidine kinase
N8D55_06155	COG0784	Response regulator, receiver
N8D55_06175	COG0175	sulfate reduction
N8D55_06205	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
N8D55_06230	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
N8D55_06260	COG3039	Transposase
N8D55_06275	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
N8D55_06280	COG2272	Belongs to the type-B carboxylesterase lipase family
N8D55_06290	COG4948	Mandelate Racemase Muconate Lactonizing
N8D55_06305	COG1609	Transcriptional regulator
N8D55_06335	COG3273	potassium ion transport
N8D55_06335	COG0471	metal ion transport
N8D55_06340	COG0220	tRNA (guanine-N7-)-methyltransferase activity
N8D55_06385	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
N8D55_06420	COG2801	Transposase and inactivated derivatives
N8D55_06425	COG3220	belongs to the UPF0276 family
N8D55_06570	COG2801	Transposase and inactivated derivatives
N8D55_06620	COG2814	Major facilitator Superfamily
N8D55_06645	COG3039	Transposase
N8D55_06695	COG2856	Zn peptidase
N8D55_06710	COG0583	DNA-binding transcription factor activity
N8D55_06715	COG1238	metal cluster binding
N8D55_06765	COG0189	ligase activity
N8D55_06770	COG0745	RESPONSE REGULATOR receiver
N8D55_06800	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
N8D55_06810	COG4969	Belongs to the N-Me-Phe pilin family
N8D55_06815	COG2194	sulfuric ester hydrolase activity
N8D55_06860	COG0045	succinate-CoA ligase (ADP-forming) activity
N8D55_06865	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
N8D55_06910	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
N8D55_06915	COG0564	pseudouridine synthase activity
N8D55_06930	COG3011	Protein conserved in bacteria
N8D55_06935	COG0840	transmembrane signaling receptor activity
N8D55_07000	COG4771	TonB-dependent receptor
N8D55_07010	COG0667	Aldo Keto reductase
N8D55_07015	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
N8D55_07020	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N8D55_07025	COG1116	anion transmembrane transporter activity
N8D55_07030	COG0542	response to heat
N8D55_07040	COG4206	TonB-dependent receptor
N8D55_07055	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
N8D55_07075	COG5599	Phosphatase
N8D55_07085	COG0019	diaminopimelate decarboxylase activity
N8D55_07090	COG4264	IucA IucC family
N8D55_07095	COG2814	Major facilitator Superfamily
N8D55_07100	COG4264	IucA IucC family
N8D55_07110	COG4772	TonB-dependent receptor
N8D55_07145	COG0488	(ABC) transporter
N8D55_07215	COG2255	four-way junction helicase activity
N8D55_07220	COG0824	Thioesterase
N8D55_07245	COG2885	chlorophyll binding
N8D55_07260	COG0667	Aldo Keto reductase
N8D55_07305	COG1187	pseudouridine synthase activity
N8D55_07320	COG0514	ATP-dependent DNA helicase (RecQ)
N8D55_07325	COG0783	Belongs to the Dps family
N8D55_07350	COG0535	radical SAM domain protein
N8D55_07365	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
N8D55_07375	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
N8D55_07385	COG1216	Glycosyl transferase, family 2
N8D55_07390	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N8D55_07415	COG0189	ligase activity
N8D55_07430	COG0835	chemotaxis
N8D55_07435	COG0840	transmembrane signaling receptor activity
N8D55_07440	COG0643	Histidine kinase
N8D55_07440	COG0784	Response regulator, receiver
N8D55_07440	COG2198	Histidine kinase
N8D55_07445	COG2201	protein-glutamate methylesterase activity
N8D55_07480	COG2304	oxidoreductase activity
N8D55_07485	COG1446	asparaginase
N8D55_07515	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
N8D55_07525	COG0732	type I restriction modification DNA specificity domain
N8D55_07530	COG3645	SOS response
N8D55_07575	COG3537	Alpha-1,2-mannosidase
N8D55_07585	COG1486	melibiose metabolic process
N8D55_07595	COG0531	amino acid
N8D55_07610	COG1472	Belongs to the glycosyl hydrolase 3 family
N8D55_07625	COG3525	Glycosyl hydrolase, family 20, catalytic domain
N8D55_07660	COG0494	nUDIX hydrolase
N8D55_07665	COG1218	3'(2'),5'-bisphosphate nucleotidase
N8D55_07670	COG3956	TIGRFAM MazG family protein
N8D55_07675	COG1742	UPF0060 membrane protein
N8D55_07685	COG0509	glycine decarboxylation via glycine cleavage system
N8D55_07710	COG1960	acyl-CoA dehydrogenase activity
N8D55_07745	COG0463	Glycosyl transferase, family 2
N8D55_07750	COG0516	GMP reductase activity
N8D55_07750	COG0517	IMP dehydrogenase activity
N8D55_07780	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
N8D55_07785	COG0626	cystathionine gamma-synthase activity
N8D55_07790	COG0460	homoserine dehydrogenase
N8D55_07790	COG0527	aspartate kinase activity
N8D55_07815	COG1278	Cold shock
N8D55_07825	COG3038	cytochrome b561
N8D55_07830	COG2353	YceI-like domain
N8D55_07855	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
N8D55_07865	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
N8D55_07875	COG0259	pyridoxamine-phosphate oxidase activity
N8D55_07890	COG1842	Phage shock protein A
N8D55_07915	COG0754	glutathionylspermidine amidase activity
N8D55_07925	COG0789	Transcriptional regulator
N8D55_07975	COG0531	amino acid
N8D55_07995	COG1113	amino acid transport
N8D55_08005	COG1271	oxidase subunit
N8D55_08010	COG1294	oxidase, subunit
N8D55_08020	COG2239	Acts as a magnesium transporter
N8D55_08030	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
N8D55_08050	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N8D55_08065	COG1137	ATPase activity
N8D55_08070	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
N8D55_08115	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
N8D55_08135	COG0628	permease
N8D55_08175	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
N8D55_08180	COG0084	hydrolase, TatD family'
N8D55_08195	COG1960	acyl-CoA dehydrogenase activity
N8D55_08210	COG0367	asparagine synthase
N8D55_08220	COG0305	Participates in initiation and elongation during chromosome replication
N8D55_08235	COG0583	DNA-binding transcription factor activity
N8D55_08280	COG3706	GGDEF domain
N8D55_08385	COG0556	nucleotide-excision repair
N8D55_08400	COG3505	Type IV secretory pathway VirD4
N8D55_08455	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
N8D55_08460	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
N8D55_08475	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
N8D55_08480	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N8D55_08480	COG0072	phenylalanine-tRNA ligase activity
N8D55_08535	COG0438	transferase activity, transferring glycosyl groups
N8D55_08570	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
N8D55_08575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N8D55_08580	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N8D55_08600	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
N8D55_08610	COG1960	acyl-CoA dehydrogenase activity
N8D55_08620	COG3040	lipid binding
N8D55_08640	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
N8D55_08650	COG0784	Response regulator, receiver
N8D55_08650	COG4191	Histidine kinase
N8D55_08660	COG1194	a g-specific adenine glycosylase
N8D55_08665	COG0552	protein localization to endoplasmic reticulum
N8D55_08695	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N8D55_08705	COG0006	proline dipeptidase activity
N8D55_08800	COG0742	ribosomal rna small subunit methyltransferase
N8D55_08815	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
N8D55_08820	COG0405	Gamma-glutamyltransferase
N8D55_08830	COG3291	Pkd domain containing protein
N8D55_08870	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
N8D55_08890	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
N8D55_08895	COG2801	Transposase and inactivated derivatives
N8D55_08940	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N8D55_08940	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N8D55_08945	COG1105	Belongs to the carbohydrate kinase PfkB family
N8D55_08950	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
N8D55_08950	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
N8D55_08955	COG1609	Transcriptional regulator
N8D55_08960	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
N8D55_08965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N8D55_08975	COG2902	Dehydrogenase
N8D55_08985	COG3321	synthase
N8D55_08985	COG0604	alcohol dehydrogenase
N8D55_08995	COG1902	pentaerythritol trinitrate reductase activity
N8D55_09005	COG0300	oxidoreductase activity
N8D55_09010	COG0604	alcohol dehydrogenase
N8D55_09020	COG0477	Major facilitator Superfamily
N8D55_09035	COG2733	membrane
N8D55_09050	COG1121	(ABC) transporter
N8D55_09060	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
N8D55_09095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N8D55_09100	COG0174	glutamine synthetase
N8D55_09140	COG3842	ATPase activity
N8D55_09150	COG1176	ABC-type spermidine putrescine transport system, permease component I
N8D55_09155	COG1177	transmembrane transport
N8D55_09170	COG1012	belongs to the aldehyde dehydrogenase family
N8D55_09185	COG4535	Mg2 and Co2 transporter CorC
N8D55_09200	COG1702	phosphate starvation-inducible protein PhoH
N8D55_09220	COG0741	lytic transglycosylase activity
N8D55_09235	COG2857	Cytochrome c1
N8D55_09245	COG2969	positive regulation of protein catabolic process
N8D55_09260	COG2094	Belongs to the DNA glycosylase MPG family
N8D55_09265	COG0840	transmembrane signaling receptor activity
N8D55_09270	COG0835	chemotaxis
N8D55_09275	COG2199	diguanylate cyclase activity
N8D55_09305	COG1262	PFAM Formylglycine-generating sulfatase enzyme
N8D55_09325	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
N8D55_09325	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
N8D55_09360	COG1028	Short-chain dehydrogenase reductase Sdr
N8D55_09365	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
N8D55_09370	COG0501	Belongs to the peptidase M48B family
N8D55_09385	COG4681	YaeQ
N8D55_09390	COG1671	Belongs to the UPF0178 family
N8D55_09400	COG0625	glutathione transferase activity
N8D55_09420	COG0513	Belongs to the DEAD box helicase family
N8D55_09440	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
N8D55_09445	COG0483	inositol monophosphate 1-phosphatase activity
N8D55_09460	COG3300	MHYT domain
N8D55_09460	COG5001	Diguanylate cyclase
N8D55_09545	COG4302	ethanolamine ammonia-lyase activity
N8D55_09550	COG4303	Ethanolamine ammonia lyase large subunit
N8D55_09585	COG2166	iron-sulfur cluster assembly
N8D55_09590	COG0215	cysteine-tRNA ligase activity
N8D55_09600	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
N8D55_09605	COG0137	argininosuccinate synthase activity
N8D55_09610	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N8D55_09615	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
N8D55_09630	COG0165	Argininosuccinate lyase
N8D55_09675	COG1294	oxidase, subunit
N8D55_09685	COG4988	ABC transporter
N8D55_09690	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
N8D55_09730	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
N8D55_09755	COG0436	Aminotransferase
N8D55_09760	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
N8D55_09785	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
N8D55_09790	COG2350	Protein conserved in bacteria
N8D55_09815	COG1653	transport
N8D55_09820	COG1175	transmembrane transport
N8D55_09825	COG0395	ABC-type sugar transport system, permease component
N8D55_09850	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
N8D55_09855	COG2957	Belongs to the agmatine deiminase family
N8D55_09870	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
N8D55_09875	COG0539	negative regulation of cytoplasmic translation
N8D55_09890	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
N8D55_09905	COG1210	Utp--glucose-1-phosphate uridylyltransferase
N8D55_09910	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
N8D55_09910	COG0475	glutathione-regulated potassium exporter activity
N8D55_09920	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
N8D55_09995	COG2801	Transposase and inactivated derivatives
N8D55_10030	COG2801	Transposase and inactivated derivatives
N8D55_10085	COG0840	transmembrane signaling receptor activity
N8D55_10105	COG5002	protein histidine kinase activity
N8D55_10105	COG2205	protein histidine kinase activity
N8D55_10105	COG0784	Response regulator, receiver
N8D55_10110	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
N8D55_10130	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N8D55_10140	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
N8D55_10150	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
N8D55_10215	COG2244	polysaccharide biosynthetic process
N8D55_10245	COG2264	protein methyltransferase activity
N8D55_10250	COG0297	glycogen (starch) synthase activity
N8D55_10255	COG0438	transferase activity, transferring glycosyl groups
N8D55_10270	COG1136	(ABC) transporter
N8D55_10275	COG1132	(ABC) transporter
N8D55_10285	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N8D55_10300	COG1253	flavin adenine dinucleotide binding
N8D55_10335	COG0504	CTP synthase activity
N8D55_10350	COG0148	phosphopyruvate hydratase activity
N8D55_10355	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
N8D55_10360	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
N8D55_10365	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
N8D55_10375	COG2840	Smr protein MutS2
N8D55_10380	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
N8D55_10385	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
N8D55_10390	COG1238	metal cluster binding
N8D55_10405	COG1534	Rna-binding protein
N8D55_10410	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
N8D55_10420	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
N8D55_10425	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
N8D55_10435	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
N8D55_10440	COG1546	Belongs to the CinA family
N8D55_10455	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
N8D55_10465	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
N8D55_10470	COG2137	regulation of response to DNA damage stimulus
N8D55_10475	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
N8D55_10480	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
N8D55_10495	COG1741	Belongs to the pirin family
N8D55_10500	COG0583	DNA-binding transcription factor activity
N8D55_10535	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
N8D55_10555	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N8D55_10565	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
N8D55_10580	COG4948	Mandelate Racemase Muconate Lactonizing
N8D55_10585	COG0800	Aldolase
N8D55_10620	COG1501	Belongs to the glycosyl hydrolase 31 family
N8D55_10630	COG1070	Carbohydrate kinase
N8D55_10635	COG2115	Belongs to the xylose isomerase family
N8D55_10640	COG0477	Major facilitator Superfamily
N8D55_10660	COG0860	N-Acetylmuramoyl-L-alanine amidase
N8D55_10685	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
N8D55_10690	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
N8D55_10720	COG1472	Belongs to the glycosyl hydrolase 3 family
N8D55_10730	COG5001	Diguanylate cyclase
N8D55_10730	COG4251	negative regulation of phosphorylation
N8D55_10730	COG3706	GGDEF domain
N8D55_10730	COG2203	Gaf domain
N8D55_10740	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
N8D55_10755	COG0671	phosphoesterase, PA-phosphatase related
N8D55_10780	COG0812	UDP-N-acetylmuramate dehydrogenase activity
N8D55_10785	COG0167	dihydroorotate dehydrogenase activity
N8D55_10800	COG1012	belongs to the aldehyde dehydrogenase family
N8D55_10820	COG3209	COG3209 Rhs family protein
N8D55_10850	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
N8D55_10855	COG0460	homoserine dehydrogenase
N8D55_10855	COG0527	aspartate kinase activity
N8D55_10885	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N8D55_10900	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
N8D55_10905	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
N8D55_10910	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
N8D55_10925	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
N8D55_10930	COG0107	imidazoleglycerol-phosphate synthase activity
N8D55_10950	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
N8D55_10965	COG0531	amino acid
N8D55_10980	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
N8D55_10985	COG0277	FAD linked oxidase domain protein
N8D55_11005	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
N8D55_11020	COG1024	Enoyl-CoA hydratase
N8D55_11040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N8D55_11065	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
N8D55_11100	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
N8D55_11110	COG2205	protein histidine kinase activity
N8D55_11110	COG0784	Response regulator, receiver
N8D55_11110	COG2198	Histidine kinase
N8D55_11115	COG2205	protein histidine kinase activity
N8D55_11115	COG2198	Histidine kinase
N8D55_11115	COG0784	Response regulator, receiver
N8D55_11120	COG1024	Enoyl-CoA hydratase
N8D55_11170	COG2201	protein-glutamate methylesterase activity
N8D55_11185	COG0840	transmembrane signaling receptor activity
N8D55_11195	COG0835	chemotaxis
N8D55_11205	COG0840	transmembrane signaling receptor activity
N8D55_11220	COG0840	transmembrane signaling receptor activity
N8D55_11225	COG0840	transmembrane signaling receptor activity
N8D55_11240	COG0840	transmembrane signaling receptor activity
N8D55_11240	COG0840	transmembrane signaling receptor activity
N8D55_11250	COG0840	transmembrane signaling receptor activity
N8D55_11260	COG0643	Histidine kinase
N8D55_11260	COG2198	Histidine kinase
N8D55_11265	COG0745	RESPONSE REGULATOR receiver
N8D55_11275	COG0835	chemotaxis
N8D55_11280	COG1192	Involved in chromosome partitioning
N8D55_11290	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
N8D55_11315	COG4771	TonB-dependent receptor
N8D55_11340	COG1169	isochorismate synthase
N8D55_11370	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N8D55_11370	COG2226	methyltransferase
N8D55_11370	COG3433	isochorismatase activity
N8D55_11380	COG2226	methyltransferase
N8D55_11380	COG3433	isochorismatase activity
N8D55_11380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N8D55_11405	COG2226	methyltransferase
N8D55_11405	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N8D55_11405	COG3433	isochorismatase activity
N8D55_11410	COG2226	methyltransferase
N8D55_11410	COG3433	isochorismatase activity
N8D55_11410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N8D55_11430	COG4771	TonB-dependent receptor
N8D55_11445	COG1132	(ABC) transporter
N8D55_11450	COG1132	(ABC) transporter
N8D55_11505	COG5001	Diguanylate cyclase
N8D55_11505	COG3300	MHYT domain
N8D55_11525	COG3190	flagellar
N8D55_11575	COG1677	Flagellar hook-basal body complex protein FliE
N8D55_11595	COG3039	Transposase
N8D55_11625	COG1028	Short-chain dehydrogenase reductase Sdr
N8D55_11630	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
N8D55_11650	COG2201	protein-glutamate methylesterase activity
N8D55_11680	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
N8D55_11685	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
N8D55_11700	COG1705	Flagellar rod assembly protein muramidase FlgJ
N8D55_11700	COG3951	Flagellar rod assembly protein muramidase FlgJ
N8D55_11720	COG4787	bacterial-type flagellum-dependent cell motility
N8D55_11730	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
N8D55_11735	COG1558	bacterial-type flagellum-dependent cell motility
N8D55_11765	COG4191	Histidine kinase
N8D55_11820	COG0542	response to heat
N8D55_11830	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
N8D55_11845	COG1674	ftsk spoiiie
N8D55_11860	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
N8D55_11870	COG0183	Belongs to the thiolase family
N8D55_11875	COG1024	Enoyl-CoA hydratase
N8D55_11875	COG1250	3-hydroxyacyl-CoA dehydrogenase
N8D55_11890	COG0820	rRNA (adenine-C2-)-methyltransferase activity
N8D55_11900	COG1426	Protein conserved in bacteria
N8D55_11910	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
N8D55_11915	COG1160	GTP binding
N8D55_11935	COG0708	Exodeoxyribonuclease III
N8D55_11950	COG0746	molybdenum cofactor guanylyltransferase activity
N8D55_11960	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
N8D55_11960	COG1648	precorrin-2 dehydrogenase activity
N8D55_11970	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
N8D55_11990	COG0243	molybdopterin cofactor binding
N8D55_12010	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
N8D55_12035	COG0579	oxidoreductase
N8D55_12060	COG3685	Protein conserved in bacteria
N8D55_12075	COG5001	Diguanylate cyclase
N8D55_12100	COG2205	protein histidine kinase activity
N8D55_12120	COG3713	MltA-interacting MipA family protein
N8D55_12155	COG0784	Response regulator, receiver
N8D55_12155	COG4191	Histidine kinase
N8D55_12190	COG4191	Histidine kinase
N8D55_12195	COG2197	response regulator
N8D55_12225	COG0840	transmembrane signaling receptor activity
N8D55_12270	COG0488	(ABC) transporter
N8D55_12365	COG0653	protein targeting
N8D55_12370	COG0653	protein targeting
N8D55_12385	COG2154	pterin-4-alpha-carbinolamine dehydratase
N8D55_12505	COG1304	FMN binding
N8D55_12510	COG1247	-acetyltransferase
N8D55_12525	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
N8D55_12530	COG0322	excinuclease ABC activity
N8D55_12540	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
N8D55_12545	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
N8D55_12555	COG1132	(ABC) transporter
N8D55_12565	COG0811	peptide transport
N8D55_12580	COG1136	(ABC) transporter
N8D55_12585	COG4591	ABC-type transport system involved in lipoprotein release permease component
N8D55_12595	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
N8D55_12600	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
N8D55_12615	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
N8D55_12620	COG2009	succinate dehydrogenase
N8D55_12640	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
N8D55_12645	COG0837	glucose binding
N8D55_12650	COG0363	glucosamine-6-phosphate deaminase activity
N8D55_12655	COG0129	dihydroxy-acid dehydratase activity
N8D55_12660	COG0800	Aldolase
N8D55_12725	COG0784	Response regulator, receiver
N8D55_12725	COG2205	protein histidine kinase activity
N8D55_12725	COG5002	protein histidine kinase activity
N8D55_12730	COG2183	response to ionizing radiation
N8D55_12755	COG3243	poly(R)-hydroxyalkanoic acid synthase
N8D55_12765	COG1183	phosphatidylcholine synthase activity
N8D55_12770	COG1028	Short-chain dehydrogenase reductase Sdr
N8D55_12800	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
N8D55_12865	COG1335	isochorismatase
N8D55_12875	COG4585	Histidine kinase
N8D55_12925	COG0583	DNA-binding transcription factor activity
N8D55_12945	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
N8D55_12950	COG0077	Prephenate dehydratase
N8D55_12950	COG1605	Chorismate mutase
N8D55_12955	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
N8D55_12960	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
N8D55_13000	COG1228	amidohydrolase
N8D55_13020	COG2801	Transposase and inactivated derivatives
N8D55_13035	COG4993	Dehydrogenase
N8D55_13045	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
N8D55_13065	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
N8D55_13095	COG0316	Belongs to the HesB IscA family
N8D55_13100	COG0017	Asparaginyl-tRNA synthetase
N8D55_13115	COG2808	Putative FMN-binding domain
N8D55_13120	COG0288	reversible hydration of carbon dioxide
N8D55_13140	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N8D55_13145	COG2925	Exonuclease
N8D55_13240	COG1024	Enoyl-CoA hydratase
N8D55_13250	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
N8D55_13255	COG0659	secondary active sulfate transmembrane transporter activity
N8D55_13280	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
N8D55_13285	COG0573	inorganic phosphate transmembrane transporter activity
N8D55_13290	COG0581	inorganic phosphate transmembrane transporter activity
N8D55_13300	COG0704	Plays a role in the regulation of phosphate uptake
N8D55_13320	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
N8D55_13330	COG0557	exoribonuclease II activity
N8D55_13350	COG2226	methyltransferase
N8D55_13355	COG1410	methionine synthase
N8D55_13355	COG0646	methionine synthase
N8D55_13370	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N8D55_13410	COG0386	Belongs to the glutathione peroxidase family
N8D55_13450	COG1253	flavin adenine dinucleotide binding
N8D55_13500	COG1619	proteins homologs of microcin C7 resistance protein MccF
N8D55_13515	COG0583	DNA-binding transcription factor activity
N8D55_13520	COG2274	protein secretion by the type I secretion system
N8D55_13545	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
N8D55_13560	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
N8D55_13565	COG1420	regulation of RNA biosynthetic process
N8D55_13570	COG0497	DNA recombination
N8D55_13580	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
N8D55_13595	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
N8D55_13615	COG2801	Transposase and inactivated derivatives
N8D55_13740	COG1611	Belongs to the LOG family
N8D55_13750	COG2095	MarC family integral membrane protein
N8D55_13760	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
N8D55_13805	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
N8D55_13810	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
N8D55_13815	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
N8D55_13825	COG0195	Participates in both transcription termination and antitermination
N8D55_13840	COG1007	ATP synthesis coupled electron transport
N8D55_13860	COG0839	Belongs to the complex I subunit 6 family
N8D55_13870	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
N8D55_13880	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
N8D55_13885	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
N8D55_13890	COG0649	NAD binding
N8D55_13895	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
N8D55_13905	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
N8D55_13925	COG4221	oxidoreductase activity
N8D55_13955	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N8D55_13965	COG0159	tryptophan synthase activity
N8D55_13975	COG0133	tryptophan synthase activity
N8D55_13990	COG0101	tRNA pseudouridine synthase activity
N8D55_14005	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
N8D55_14010	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
N8D55_14025	COG2890	protein-(glutamine-N5) methyltransferase activity
N8D55_14035	COG0688	phosphatidylethanolamine metabolic process
N8D55_14100	COG0717	Belongs to the dCTP deaminase family
N8D55_14105	COG0489	protein tyrosine kinase activity
N8D55_14125	COG3590	peptidase
N8D55_14170	COG1047	Peptidyl-prolyl cis-trans
N8D55_14180	COG0791	NLP P60 protein
N8D55_14210	COG4191	Histidine kinase
N8D55_14225	COG1301	dicarboxylic acid transport
N8D55_14230	COG1785	Belongs to the alkaline phosphatase family
N8D55_14235	COG0037	tRNA processing
N8D55_14240	COG1722	exodeoxyribonuclease VII activity
N8D55_14245	COG0142	geranyltranstransferase activity
N8D55_14260	COG0312	modulator of DNA gyrase
N8D55_14270	COG0312	modulator of DNA gyrase
N8D55_14305	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
N8D55_14325	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
N8D55_14340	COG0495	leucyl-tRNA aminoacylation
N8D55_14350	COG3118	belongs to the thioredoxin family
N8D55_14360	COG2155	Conserved Protein
N8D55_14400	COG1132	(ABC) transporter
N8D55_14420	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
N8D55_14440	COG1187	pseudouridine synthase activity
N8D55_14455	COG1595	DNA-templated transcription, initiation
N8D55_14575	COG0667	Aldo Keto reductase
N8D55_14580	COG2814	Major facilitator Superfamily
N8D55_14585	COG0583	DNA-binding transcription factor activity
N8D55_14615	COG0667	Aldo Keto reductase
N8D55_14620	COG1309	transcriptional regulator
N8D55_14630	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
N8D55_14645	COG0735	belongs to the Fur family
N8D55_14650	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
N8D55_14675	COG4452	Inner membrane protein CreD
N8D55_14690	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
N8D55_14755	COG0840	transmembrane signaling receptor activity
N8D55_14760	COG0835	chemotaxis
N8D55_14765	COG2202	Pas domain
N8D55_14765	COG2200	EAL domain
N8D55_14765	COG2199	diguanylate cyclase activity
N8D55_14795	COG0588	phosphoglycerate mutase activity
N8D55_14800	COG1515	deoxyribonuclease V activity
N8D55_14825	COG1966	Carbon starvation protein
N8D55_14830	COG2879	small protein
N8D55_14835	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N8D55_14865	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
N8D55_14870	COG1529	Aldehyde oxidase and xanthine dehydrogenase
N8D55_14880	COG2080	2 iron, 2 sulfur cluster binding
N8D55_14885	COG5001	Diguanylate cyclase
N8D55_14885	COG4251	negative regulation of phosphorylation
N8D55_14885	COG3706	GGDEF domain
N8D55_14885	COG2203	Gaf domain
N8D55_14890	COG1228	amidohydrolase
N8D55_14905	COG0629	single-stranded DNA binding
N8D55_14910	COG0142	geranyltranstransferase activity
N8D55_14930	COG0527	aspartate kinase activity
N8D55_14955	COG1764	response to oxidative stress
N8D55_14965	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
N8D55_14970	COG1678	Uncharacterized ACR, COG1678
N8D55_14995	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
N8D55_15010	COG4942	peptidase
N8D55_15045	COG0396	ATPase activity
N8D55_15050	COG0719	Fe-S assembly protein
N8D55_15055	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
N8D55_15070	COG4774	siderophore transport
N8D55_15100	COG1477	protein flavinylation
N8D55_15115	COG1555	photosystem II stabilization
N8D55_15130	COG3178	'Phosphotransferase
N8D55_15135	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
N8D55_15140	COG3293	Transposase
N8D55_15155	COG0288	reversible hydration of carbon dioxide
N8D55_15180	COG0386	Belongs to the glutathione peroxidase family
N8D55_15240	COG2814	Major facilitator Superfamily
N8D55_15245	COG1566	PFAM secretion protein HlyD family protein
N8D55_15290	COG4774	siderophore transport
N8D55_15300	COG0367	asparagine synthase
N8D55_15375	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
N8D55_15385	COG0528	UMP kinase activity
N8D55_15395	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
N8D55_15400	COG0575	Belongs to the CDS family
N8D55_15405	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
N8D55_15410	COG0750	zinc metalloprotease
N8D55_15430	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
N8D55_15440	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
N8D55_15460	COG0825	malonyl-CoA metabolic process
N8D55_15470	COG1981	membrane
N8D55_15490	COG1695	Transcriptional regulator
N8D55_15515	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
N8D55_15540	COG2040	homocysteine
N8D55_15550	COG0346	lactoylglutathione lyase activity
N8D55_15555	COG1131	(ABC) transporter
N8D55_15570	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N8D55_15570	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N8D55_15580	COG2878	Part of a membrane complex involved in electron transport
N8D55_15595	COG1595	DNA-templated transcription, initiation
N8D55_15620	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
N8D55_15645	COG0251	oxidation-reduction process
N8D55_15695	COG1902	pentaerythritol trinitrate reductase activity
N8D55_15710	COG2824	Alkylphosphonate utilization operon protein PhnA
N8D55_15720	COG1047	Peptidyl-prolyl cis-trans
N8D55_15760	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
N8D55_15770	COG5487	UPF0391 membrane protein
N8D55_15775	COG1451	nucleotide metabolic process
N8D55_15795	COG0183	Belongs to the thiolase family
N8D55_15825	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
N8D55_15825	COG1793	dna ligase
N8D55_15835	COG1793	dna ligase
N8D55_15840	COG1201	RNA secondary structure unwinding
N8D55_15855	COG1278	Cold shock
N8D55_15860	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
N8D55_15865	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
N8D55_15870	COG1472	Belongs to the glycosyl hydrolase 3 family
N8D55_15875	COG3046	protein related to deoxyribodipyrimidine photolyase
N8D55_15880	COG1233	COG1233 Phytoene dehydrogenase and related
N8D55_15885	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
N8D55_15890	COG2954	triphosphatase activity
N8D55_15915	COG1381	Involved in DNA repair and RecF pathway recombination
N8D55_15945	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N8D55_15960	COG1250	3-hydroxyacyl-CoA dehydrogenase
N8D55_15960	COG1024	Enoyl-CoA hydratase
N8D55_15970	COG0457	Tetratricopeptide repeat
N8D55_16005	COG1024	Enoyl-CoA hydratase
N8D55_16010	COG1960	acyl-CoA dehydrogenase activity
N8D55_16045	COG0436	Aminotransferase
N8D55_16060	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
N8D55_16095	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
N8D55_16105	COG0534	Mate efflux family protein
N8D55_16115	COG0336	Belongs to the RNA methyltransferase TrmD family
N8D55_16120	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
N8D55_16150	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
N8D55_16200	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
N8D55_16205	COG2201	protein-glutamate methylesterase activity
N8D55_16210	COG2205	protein histidine kinase activity
N8D55_16215	COG5507	3-demethylubiquinone-9 3-methyltransferase
N8D55_16255	COG2172	sigma factor antagonist activity
N8D55_16270	COG1902	pentaerythritol trinitrate reductase activity
N8D55_16285	COG2207	Transcriptional regulator
N8D55_16295	COG3152	Membrane
N8D55_16310	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
N8D55_16320	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
N8D55_16340	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
N8D55_16350	COG0196	riboflavin kinase activity
N8D55_16365	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
N8D55_16370	COG0211	Belongs to the bacterial ribosomal protein bL27 family
N8D55_16380	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
N8D55_16385	COG0824	Thioesterase
N8D55_16420	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
N8D55_16475	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
N8D55_16490	COG2197	response regulator
N8D55_16495	COG4585	Histidine kinase
N8D55_16510	COG2894	cell division
N8D55_16515	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
N8D55_16525	COG5002	protein histidine kinase activity
N8D55_16530	COG0745	RESPONSE REGULATOR receiver
N8D55_16545	COG2194	sulfuric ester hydrolase activity
N8D55_16580	COG0656	L-ascorbic acid biosynthetic process
N8D55_16590	COG0753	catalase activity
N8D55_16595	COG1917	Cupin 2, conserved barrel domain protein
N8D55_16595	COG2207	Transcriptional regulator
N8D55_16615	COG1297	OPT oligopeptide transporter protein
N8D55_16630	COG0587	DNA-directed DNA polymerase activity
N8D55_16695	COG1529	Aldehyde oxidase and xanthine dehydrogenase
N8D55_16705	COG1064	alcohol dehydrogenase
N8D55_16860	COG2189	Belongs to the N(4) N(6)-methyltransferase family
N8D55_16900	COG2801	Transposase and inactivated derivatives
N8D55_16910	COG0732	type I restriction modification DNA specificity domain
N8D55_16960	COG0330	HflC and HflK could
N8D55_16965	COG0330	HflC and HflK could
N8D55_16985	COG0678	peroxiredoxin activity
N8D55_16995	COG4953	penicillin-binding protein 1C
N8D55_17060	COG3829	transcription factor binding
N8D55_17070	COG2161	toxin-antitoxin pair type II binding
N8D55_17075	COG4115	mRNA cleavage
N8D55_17095	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
N8D55_17100	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
N8D55_17120	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
N8D55_17130	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
N8D55_17135	COG0333	Belongs to the bacterial ribosomal protein bL32 family
N8D55_17140	COG1399	metal-binding, possibly nucleic acid-binding protein
N8D55_17145	COG0424	maF-like protein
N8D55_17160	COG0714	Associated with various cellular activities
N8D55_17180	COG0537	adenosine 5'-monophosphoramidase activity
N8D55_17190	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
N8D55_17295	COG0314	molybdopterin synthase activity
N8D55_17300	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
N8D55_17305	COG0315	cyclic pyranopterin monophosphate synthase activity
N8D55_17310	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
N8D55_17360	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N8D55_17400	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
N8D55_17410	COG0544	peptidyl-prolyl cis-trans isomerase activity
N8D55_17455	COG0473	3-isopropylmalate dehydrogenase activity
N8D55_17475	COG0745	RESPONSE REGULATOR receiver
N8D55_17500	COG0671	phosphoesterase, PA-phosphatase related
N8D55_17505	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
N8D55_17515	COG3291	Pkd domain containing protein
N8D55_17540	COG0285	dihydrofolate synthase activity
N8D55_17555	COG0406	alpha-ribazole phosphatase activity
N8D55_17590	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
N8D55_17600	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
N8D55_17605	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
N8D55_17610	COG0156	8-amino-7-oxononanoate synthase activity
N8D55_17630	COG2885	chlorophyll binding
N8D55_17635	COG0604	alcohol dehydrogenase
N8D55_17660	COG0625	glutathione transferase activity
N8D55_17670	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
N8D55_17675	COG1217	gtp-binding protein TYPA
N8D55_17685	COG0154	amidase activity
N8D55_17695	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
N8D55_17705	COG0203	ribosomal protein L17
N8D55_17730	COG0201	protein transport
N8D55_17775	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
N8D55_17785	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
N8D55_17790	COG0255	Belongs to the universal ribosomal protein uL29 family
N8D55_17805	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
N8D55_17815	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
N8D55_17835	COG0051	transcription antitermination factor activity, RNA binding
N8D55_17840	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
N8D55_17855	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
N8D55_17860	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
N8D55_17870	COG0222	ribosome binding
N8D55_17875	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
N8D55_17880	COG0081	regulation of translation
N8D55_17885	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
N8D55_17890	COG0250	Participates in transcription elongation, termination and antitermination
N8D55_17895	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
N8D55_17930	COG0193	aminoacyl-tRNA hydrolase activity
N8D55_17935	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
N8D55_17940	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
N8D55_17955	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
N8D55_17980	COG0521	Mo-molybdopterin cofactor biosynthetic process
N8D55_18030	COG1404	Belongs to the peptidase S8 family
N8D55_18035	COG1404	Belongs to the peptidase S8 family
N8D55_18045	COG1404	Belongs to the peptidase S8 family
N8D55_18050	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N8D55_18115	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
N8D55_18115	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
N8D55_18135	COG2890	protein-(glutamine-N5) methyltransferase activity
N8D55_18145	COG3634	alkyl hydroperoxide reductase activity
N8D55_18155	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
N8D55_18170	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
N8D55_18180	COG2197	response regulator
N8D55_18240	COG3386	PFAM SMP-30 Gluconolaconase
N8D55_18260	COG1024	Enoyl-CoA hydratase
N8D55_18310	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N8D55_18330	COG0123	including yeast histone deacetylase and acetoin utilization protein
N8D55_18345	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
N8D55_18350	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
N8D55_18355	COG2967	ApaG domain
N8D55_18365	COG0431	NADPH-dependent FMN reductase
N8D55_18370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N8D55_18380	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N8D55_18385	COG1116	anion transmembrane transporter activity
N8D55_18430	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
N8D55_18440	COG0642	Histidine kinase
N8D55_18455	COG4181	ATPase activity
N8D55_18465	COG2175	clavaminate synthase activity
N8D55_18475	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
N8D55_18480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N8D55_18500	COG4771	TonB-dependent receptor
N8D55_18510	COG0667	Aldo Keto reductase
N8D55_18515	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
N8D55_18530	COG4106	trans-aconitate 2-methyltransferase activity
N8D55_18540	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
N8D55_18570	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
N8D55_18585	COG2357	RelA SpoT domain protein
N8D55_18630	COG0604	alcohol dehydrogenase
N8D55_18630	COG1028	Short-chain dehydrogenase reductase Sdr
N8D55_18630	COG3321	synthase
N8D55_18640	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
N8D55_18665	COG0653	protein targeting
N8D55_18670	COG0739	heme binding
N8D55_18700	COG1181	Belongs to the D-alanine--D-alanine ligase family
N8D55_18705	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
N8D55_18725	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
N8D55_18730	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
N8D55_18740	COG3116	cell division
N8D55_18785	COG0792	nuclease activity
N8D55_18790	COG1988	membrane-bound metal-dependent
N8D55_18795	COG0277	FAD linked oxidase domain protein
N8D55_18800	COG4946	Tricorn protease homolog
N8D55_18800	COG1506	peptidase
N8D55_18800	COG0823	Involved in the tonB-independent uptake of proteins
N8D55_18805	COG0745	RESPONSE REGULATOR receiver
N8D55_18825	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
N8D55_18840	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
N8D55_18875	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
N8D55_18875	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
N8D55_18890	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
N8D55_18900	COG0488	(ABC) transporter
N8D55_18905	COG0242	peptide deformylase activity
N8D55_18920	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
N8D55_18965	COG2188	Transcriptional regulator
N8D55_18980	COG1450	Type ii and iii secretion system protein
N8D55_18995	COG3166	PFAM Fimbrial assembly family protein
N8D55_19000	COG3156	type II secretion system protein K
N8D55_19005	COG4795	General secretion pathway protein
N8D55_19010	COG2165	general secretion pathway protein
N8D55_19025	COG2165	general secretion pathway protein
N8D55_19035	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
N8D55_19075	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
N8D55_19080	COG4974	Belongs to the 'phage' integrase family
N8D55_19110	COG0525	valine-tRNA ligase activity
N8D55_19155	COG0442	prolyl-tRNA aminoacylation
N8D55_19170	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
N8D55_19175	COG1127	ABC transporter
N8D55_19180	COG3218	ABC-type transport auxiliary lipoprotein component
N8D55_19180	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
N8D55_19220	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N8D55_19225	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
N8D55_19225	COG0662	Cupin 2, conserved barrel domain protein
N8D55_19265	COG0463	Glycosyl transferase, family 2
N8D55_19290	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
N8D55_19365	COG0625	glutathione transferase activity
N8D55_19375	COG0513	Belongs to the DEAD box helicase family
N8D55_19385	COG4771	TonB-dependent receptor
N8D55_19390	COG0720	synthase
N8D55_19400	COG1569	PIN domain
N8D55_19405	COG3311	Transcriptional regulator
N8D55_19410	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
N8D55_19430	COG2819	hydrolase of the alpha beta superfamily
N8D55_19440	COG0546	phosphoglycolate phosphatase activity
N8D55_19450	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
N8D55_19465	COG0339	signal peptide processing
N8D55_19480	COG2132	Multicopper oxidase
N8D55_19530	COG1136	(ABC) transporter
N8D55_19555	COG0577	efflux transmembrane transporter activity
N8D55_19555	COG1136	(ABC) transporter
N8D55_19575	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
N8D55_19590	COG0355	proton-transporting ATP synthase activity, rotational mechanism
N8D55_19615	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
N8D55_19625	COG0356	it plays a direct role in the translocation of protons across the membrane
N8D55_19645	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N8D55_19655	COG0508	dehydrogenase complex catalyzes the overall conversion of
N8D55_19695	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
N8D55_19705	COG1666	GTP binding
N8D55_19720	COG1187	pseudouridine synthase activity
N8D55_19745	COG2205	protein histidine kinase activity
N8D55_19745	COG2198	Histidine kinase
N8D55_19745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N8D55_19745	COG0784	Response regulator, receiver
N8D55_19765	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
N8D55_19770	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N8D55_19830	COG0842	Transport permease protein
N8D55_19850	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
N8D55_19865	COG3384	dioxygenase
N8D55_19875	COG0583	DNA-binding transcription factor activity
N8D55_19885	COG0667	Aldo Keto reductase
N8D55_19910	COG0531	amino acid
N8D55_19925	COG2972	Histidine kinase
N8D55_19945	COG3685	Protein conserved in bacteria
N8D55_19950	COG3546	catalase activity
N8D55_19990	COG1028	Short-chain dehydrogenase reductase Sdr
N8D55_19995	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
N8D55_20015	COG1132	(ABC) transporter
N8D55_20025	COG1063	alcohol dehydrogenase
N8D55_20050	COG0583	DNA-binding transcription factor activity
N8D55_20055	COG2814	Major facilitator Superfamily
N8D55_20095	COG1131	(ABC) transporter
N8D55_20110	COG0251	oxidation-reduction process
N8D55_20135	COG0840	transmembrane signaling receptor activity
N8D55_20160	COG0659	secondary active sulfate transmembrane transporter activity
N8D55_20165	COG0024	Methionine aminopeptidase
N8D55_20200	COG1309	transcriptional regulator
N8D55_20210	COG1902	pentaerythritol trinitrate reductase activity
N8D55_20240	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
N8D55_20315	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
N8D55_20320	COG1490	D-aminoacyl-tRNA deacylase activity
N8D55_20325	COG1560	Kdo2-lipid A biosynthetic process
N8D55_20375	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
N8D55_20380	COG0242	peptide deformylase activity
N8D55_20390	COG0758	DNA mediated transformation
N8D55_20410	COG1754	DNA topoisomerase type I activity
N8D55_20410	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
N8D55_20430	COG1028	Short-chain dehydrogenase reductase Sdr
N8D55_20440	COG0616	signal peptide processing
N8D55_20485	COG1252	NADH dehydrogenase
N8D55_20490	COG2860	membrane
N8D55_20495	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
N8D55_20505	COG2201	protein-glutamate methylesterase activity
N8D55_20510	COG2177	Part of the ABC transporter FtsEX involved in
N8D55_20515	COG2884	Cell division ATP-binding protein ftsE
N8D55_20525	COG3118	belongs to the thioredoxin family
N8D55_20530	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
N8D55_20585	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
N8D55_20615	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
N8D55_20615	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
N8D55_20620	COG1473	amidohydrolase
N8D55_20625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N8D55_20630	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
N8D55_20680	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
N8D55_20710	COG4948	Mandelate Racemase Muconate Lactonizing
N8D55_20735	COG4682	membrane
N8D55_20755	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
N8D55_20770	COG1610	YqeY-like protein
N8D55_20775	COG1295	ribonuclease BN
N8D55_20795	COG0109	protoheme IX farnesyltransferase activity
N8D55_20840	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
N8D55_20885	COG0739	heme binding
N8D55_20900	COG2807	transmembrane transport
N8D55_20920	COG1192	Involved in chromosome partitioning
N8D55_20940	COG0463	Glycosyl transferase, family 2
N8D55_20960	COG0756	dUTP diphosphatase activity
N8D55_20975	COG0018	arginyl-trna synthetase
N8D55_20985	COG4221	oxidoreductase activity
N8D55_21010	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N8D55_21070	COG4943	cyclic-guanylate-specific phosphodiesterase activity
N8D55_21120	COG1090	epimerase
N8D55_21175	COG1011	Hydrolase
N8D55_21180	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
N8D55_21210	COG2197	response regulator
N8D55_21220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N8D55_21225	COG1136	(ABC) transporter
N8D55_21230	COG3039	Transposase
N8D55_21255	COG0697	spore germination
N8D55_21280	COG0180	Tryptophanyl-tRNA synthetase
N8D55_21285	COG3237	CsbD-like
N8D55_21325	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
N8D55_21340	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
N8D55_21345	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
N8D55_21345	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
N8D55_21385	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
N8D55_21430	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
N8D55_21560	COG0625	glutathione transferase activity
N8D55_21605	COG1476	TRANSCRIPTIONal
N8D55_21630	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
N8D55_21635	COG1131	(ABC) transporter
N8D55_21640	COG0842	Transport permease protein
N8D55_21685	COG1607	acyl-coa hydrolase
N8D55_21690	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N8D55_21710	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
N8D55_21740	COG1629	transport
N8D55_21740	COG4771	TonB-dependent receptor
N8D55_21745	COG2239	Acts as a magnesium transporter
N8D55_21760	COG3387	PFAM Glycoside hydrolase 15-related
N8D55_21770	COG3100	YcgL domain-containing protein
N8D55_21775	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
N8D55_21795	COG1028	Short-chain dehydrogenase reductase Sdr
N8D55_21835	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N8D55_21920	COG3621	Patatin-like phospholipase
N8D55_21950	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
N8D55_21960	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
N8D55_21970	COG2159	amidohydrolase
N8D55_22000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N8D55_22025	COG3540	Alkaline phosphatase
N8D55_22035	COG2091	lysine biosynthetic process via aminoadipic acid
N8D55_22050	COG0708	Exodeoxyribonuclease III
N8D55_22065	COG1940	carbohydrate kinase activity
N8D55_22095	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N8D55_22100	COG3162	membrane
N8D55_22150	COG1028	Short-chain dehydrogenase reductase Sdr
N8D55_22155	COG0179	Fumarylacetoacetate (FAA) hydrolase
N8D55_22160	COG4948	Mandelate Racemase Muconate Lactonizing
N8D55_22165	COG3254	rhamnose metabolic process
N8D55_22175	COG1414	Transcriptional regulator
N8D55_22190	COG1971	Probably functions as a manganese efflux pump
N8D55_22195	COG2205	protein histidine kinase activity
N8D55_22205	COG2211	Major facilitator Superfamily
N8D55_22210	COG3265	gluconokinase activity
N8D55_22215	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
N8D55_22240	COG2911	Protein conserved in bacteria
N8D55_22245	COG0729	surface antigen
N8D55_22250	COG4771	TonB-dependent receptor
N8D55_22255	COG0457	Tetratricopeptide repeat
N8D55_22295	COG0805	protein transport
N8D55_22300	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
N8D55_22305	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
N8D55_22315	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
N8D55_22330	COG2974	May be involved in recombination
N8D55_22335	COG0037	tRNA processing
N8D55_22355	COG3661	Belongs to the glycosyl hydrolase 67 family
N8D55_22365	COG4948	Mandelate Racemase Muconate Lactonizing
N8D55_22375	COG1472	Belongs to the glycosyl hydrolase 3 family
N8D55_22380	COG0246	Mannitol dehydrogenase
N8D55_22410	COG1620	l-lactate permease
N8D55_22430	COG3386	PFAM SMP-30 Gluconolaconase
N8D55_22445	COG1904	glucuronate isomerase
N8D55_22465	COG2211	Major facilitator Superfamily
N8D55_22500	COG2937	Belongs to the GPAT DAPAT family
N8D55_22530	COG0284	orotidine-5'-phosphate decarboxylase activity
N8D55_22535	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
N8D55_22565	COG1435	thymidine kinase activity
N8D55_22575	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
N8D55_22585	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
N8D55_22800	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
N8D55_22960	COG0653	protein targeting
N8D55_22970	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
N8D55_23155	COG0653	protein targeting
N8D55_23165	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
N8D55_23215	COG3846	protein secretion by the type IV secretion system
N8D55_23260	COG0551	DNA topoisomerase type I activity
N8D55_23260	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
N8D55_23370	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
N8D55_23475	COG4962	Type ii secretion system protein e
N8D55_23490	COG3451	type IV secretory pathway VirB4