locus-tag	class	description
XHV734_0005	COG0187	DNA topoisomerase II activity
XHV734_0007	COG0501	Belongs to the peptidase M48B family
XHV734_0016	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
XHV734_0018	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XHV734_0025	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XHV734_0026	COG0793	Belongs to the peptidase S41A family
XHV734_0027	COG4942	peptidase
XHV734_0029	COG2234	aminopeptidase activity
XHV734_0031	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XHV734_0033	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XHV734_0034	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XHV734_0035	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XHV734_0036	COG1064	alcohol dehydrogenase
XHV734_0038	COG0493	'glutamate synthase
XHV734_0039	COG0070	glutamate synthase
XHV734_0039	COG0067	glutamate synthase
XHV734_0039	COG0069	glutamate synthase activity
XHV734_0046	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XHV734_0050	COG3459	Glycosyltransferase 36 associated
XHV734_0054	COG1028	Short-chain dehydrogenase reductase Sdr
XHV734_0070	COG1205	dead DEAH box helicase
XHV734_0070	COG1111	helicase
XHV734_0073	COG1272	protein, Hemolysin III
XHV734_0078	COG1028	Short-chain dehydrogenase reductase Sdr
XHV734_0083	COG0583	DNA-binding transcription factor activity
XHV734_0084	COG1028	Short-chain dehydrogenase reductase Sdr
XHV734_0087	COG2249	NAD(P)H dehydrogenase (quinone) activity
XHV734_0091	COG1733	regulation of RNA biosynthetic process
XHV734_0098	COG2801	Transposase and inactivated derivatives
XHV734_0099	COG2963	transposase activity
XHV734_0107	COG2816	NAD+ diphosphatase activity
XHV734_0108	COG0657	acetylesterase activity
XHV734_0110	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XHV734_0120	COG0714	Associated with various cellular activities
XHV734_0131	COG4772	TonB-dependent receptor
XHV734_0133	COG0662	Cupin 2, conserved barrel domain protein
XHV734_0135	COG1012	belongs to the aldehyde dehydrogenase family
XHV734_0145	COG1755	Isoprenylcysteine carboxyl methyltransferase
XHV734_0146	COG4585	Histidine kinase
XHV734_0147	COG2197	response regulator
XHV734_0151	COG3710	Transcriptional regulator
XHV734_0153	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
XHV734_0155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XHV734_0156	COG4771	TonB-dependent receptor
XHV734_0186	COG2963	transposase activity
XHV734_0187	COG2801	Transposase and inactivated derivatives
XHV734_0202	COG0366	Alpha amylase catalytic
XHV734_0203	COG0366	Alpha amylase catalytic
XHV734_0204	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XHV734_0211	COG2755	lipolytic protein G-D-S-L family
XHV734_0213	COG2755	lipolytic protein G-D-S-L family
XHV734_0213	COG0657	acetylesterase activity
XHV734_0215	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XHV734_0219	COG3507	Belongs to the glycosyl hydrolase 43 family
XHV734_0220	COG1609	Transcriptional regulator
XHV734_0222	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
XHV734_0223	COG1028	Short-chain dehydrogenase reductase Sdr
XHV734_0225	COG2755	lipolytic protein G-D-S-L family
XHV734_0229	COG3186	Phenylalanine-4-hydroxylase
XHV734_0230	COG1522	sequence-specific DNA binding
XHV734_0232	COG1752	Esterase of the alpha-beta hydrolase superfamily
XHV734_0233	COG1119	ATPase activity
XHV734_0236	COG1125	glycine betaine transport
XHV734_0236	COG0517	IMP dehydrogenase activity
XHV734_0239	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XHV734_0241	COG3550	peptidyl-serine autophosphorylation
XHV734_0242	COG1396	sequence-specific DNA binding
XHV734_0246	COG0489	protein tyrosine kinase activity
XHV734_0247	COG2062	phosphohistidine phosphatase, SixA
XHV734_0250	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XHV734_0255	COG1881	PFAM PEBP family protein
XHV734_0259	COG0174	glutamine synthetase
XHV734_0260	COG0347	Belongs to the P(II) protein family
XHV734_0261	COG0004	ammonium transporteR
XHV734_0262	COG3852	Histidine kinase
XHV734_0263	COG2204	response regulator
XHV734_0264	COG2032	superoxide dismutase activity
XHV734_0266	COG2032	superoxide dismutase activity
XHV734_0268	COG0183	Belongs to the thiolase family
XHV734_0277	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XHV734_0279	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
XHV734_0281	COG0028	Belongs to the TPP enzyme family
XHV734_0287	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
XHV734_0291	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XHV734_0292	COG3177	Filamentation induced by cAMP protein fic
XHV734_0293	COG0596	Alpha beta hydrolase
XHV734_0294	COG0727	PFAM Uncharacterised protein family (UPF0153)
XHV734_0296	COG0318	PFAM AMP-dependent synthetase and ligase
XHV734_0300	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XHV734_0304	COG1181	Belongs to the D-alanine--D-alanine ligase family
XHV734_0307	COG0564	pseudouridine synthase activity
XHV734_0313	COG1446	asparaginase
XHV734_0314	COG0339	signal peptide processing
XHV734_0318	COG0583	DNA-binding transcription factor activity
XHV734_0319	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
XHV734_0320	COG2224	Isocitrate lyase
XHV734_0326	COG4770	biotin carboxylase activity
XHV734_0327	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XHV734_0328	COG1960	acyl-CoA dehydrogenase activity
XHV734_0339	COG0523	cobalamin synthesis protein
XHV734_0343	COG0697	spore germination
XHV734_0345	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
XHV734_0348	COG1846	Transcriptional regulator
XHV734_0349	COG1764	response to oxidative stress
XHV734_0354	COG0656	L-ascorbic acid biosynthetic process
XHV734_0355	COG2130	NADP-dependent
XHV734_0358	COG1187	pseudouridine synthase activity
XHV734_0362	COG1643	Atp-dependent helicase
XHV734_0363	COG0840	transmembrane signaling receptor activity
XHV734_0365	COG4807	Protein conserved in bacteria
XHV734_0366	COG2351	hydroxyisourate hydrolase activity
XHV734_0367	COG2072	flavoprotein involved in K transport
XHV734_0371	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
XHV734_0377	COG0596	Alpha beta hydrolase
XHV734_0397	COG2252	PERMEase
XHV734_0401	COG0084	hydrolase, TatD family'
XHV734_0404	COG0583	DNA-binding transcription factor activity
XHV734_0405	COG2814	Major facilitator Superfamily
XHV734_0410	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
XHV734_0411	COG1902	pentaerythritol trinitrate reductase activity
XHV734_0419	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XHV734_0420	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XHV734_0421	COG0583	DNA-binding transcription factor activity
XHV734_0428	COG0702	epimerase
XHV734_0430	COG1733	regulation of RNA biosynthetic process
XHV734_0433	COG2963	transposase activity
XHV734_0435	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
XHV734_0438	COG2801	Transposase and inactivated derivatives
XHV734_0444	COG2963	transposase activity
XHV734_0446	COG2801	Transposase and inactivated derivatives
XHV734_0447	COG2963	transposase activity
XHV734_0458	COG0129	dihydroxy-acid dehydratase activity
XHV734_0460	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
XHV734_0472	COG3039	Transposase
XHV734_0473	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
XHV734_0474	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
XHV734_0480	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
XHV734_0481	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
XHV734_0483	COG3485	protocatechuate 3,4-dioxygenase
XHV734_0486	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XHV734_0487	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XHV734_0489	COG1414	Transcriptional regulator
XHV734_0492	COG0657	acetylesterase activity
XHV734_0495	COG0445	tRNA wobble uridine modification
XHV734_0497	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
XHV734_0505	COG0156	8-amino-7-oxononanoate synthase activity
XHV734_0506	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
XHV734_0507	COG1040	competence protein
XHV734_0513	COG0582	viral genome integration into host DNA
XHV734_0518	COG3590	peptidase
XHV734_0524	COG3264	Mechanosensitive ion channel
XHV734_0524	COG1511	domain protein
XHV734_0525	COG1368	sulfuric ester hydrolase activity
XHV734_0526	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XHV734_0527	COG2354	Protein conserved in bacteria
XHV734_0529	COG1649	PFAM Uncharacterised BCR, COG1649
XHV734_0531	COG0297	glycogen (starch) synthase activity
XHV734_0532	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XHV734_0533	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XHV734_0538	COG0702	epimerase
XHV734_0539	COG1028	Short-chain dehydrogenase reductase Sdr
XHV734_0549	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XHV734_0551	COG0513	Belongs to the DEAD box helicase family
XHV734_0554	COG0508	dehydrogenase complex catalyzes the overall conversion of
XHV734_0557	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
XHV734_0560	COG3104	oligopeptide transport
XHV734_0565	COG2852	Protein conserved in bacteria
XHV734_0569	COG1320	monovalent cation:proton antiporter activity
XHV734_0570	COG2212	antiporter activity
XHV734_0572	COG0651	ATP synthesis coupled electron transport
XHV734_0573	COG1006	Multisubunit Na H antiporter MnhC subunit
XHV734_0574	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XHV734_0574	COG2111	Na H antiporter
XHV734_0590	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
XHV734_0594	COG1597	lipid kinase activity
XHV734_0600	COG2826	transposase and inactivated derivatives, IS30 family
XHV734_0602	COG3039	Transposase
XHV734_0603	COG2267	carboxylic ester hydrolase activity
XHV734_0607	COG2801	Transposase and inactivated derivatives
XHV734_0608	COG2963	transposase activity
XHV734_0621	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XHV734_0637	COG0840	transmembrane signaling receptor activity
XHV734_0640	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
XHV734_0642	COG0134	indole-3-glycerol-phosphate synthase activity
XHV734_0645	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XHV734_0648	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
XHV734_0660	COG0316	Belongs to the HesB IscA family
XHV734_0662	COG2816	NAD+ diphosphatase activity
XHV734_0663	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XHV734_0668	COG2814	Major facilitator Superfamily
XHV734_0669	COG1289	transmembrane transporter activity
XHV734_0670	COG0151	Belongs to the GarS family
XHV734_0671	COG0138	bifunctional purine biosynthesis protein purh
XHV734_0675	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
XHV734_0677	COG3039	Transposase
XHV734_0679	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
XHV734_0683	COG2264	protein methyltransferase activity
XHV734_0686	COG0439	Biotin carboxylase
XHV734_0688	COG0511	ligase activity, forming carbon-carbon bonds
XHV734_0689	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
XHV734_0692	COG1324	tolerance protein
XHV734_0694	COG2356	endonuclease I
XHV734_0701	COG4206	TonB-dependent receptor
XHV734_0705	COG3550	peptidyl-serine autophosphorylation
XHV734_0707	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XHV734_0714	COG3712	iron ion homeostasis
XHV734_0720	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
XHV734_0721	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XHV734_0726	COG2353	YceI-like domain
XHV734_0731	COG3052	prosthetic group binding
XHV734_0738	COG1802	Transcriptional regulator
XHV734_0762	COG0210	DNA helicase
XHV734_0782	COG0823	Involved in the tonB-independent uptake of proteins
XHV734_0782	COG1506	peptidase
XHV734_0789	COG0435	Glutathione S-transferase
XHV734_0796	COG0823	Involved in the tonB-independent uptake of proteins
XHV734_0796	COG1506	peptidase
XHV734_0805	COG0697	spore germination
XHV734_0808	COG4305	rare lipoprotein A
XHV734_0810	COG1113	amino acid transport
XHV734_0814	COG3507	Belongs to the glycosyl hydrolase 43 family
XHV734_0825	COG0840	transmembrane signaling receptor activity
XHV734_0826	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XHV734_0826	COG5297	Belongs to the glycosyl hydrolase family 6
XHV734_0827	COG0659	secondary active sulfate transmembrane transporter activity
XHV734_0831	COG2943	transferase activity, transferring hexosyl groups
XHV734_0835	COG3275	phosphorelay sensor kinase activity
XHV734_0838	COG0181	hydroxymethylbilane synthase activity
XHV734_0844	COG1505	serine-type exopeptidase activity
XHV734_0854	COG0436	Aminotransferase
XHV734_0856	COG2832	Protein of unknown function (DUF454)
XHV734_0858	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
XHV734_0860	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XHV734_0861	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
XHV734_0862	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
XHV734_0863	COG0355	proton-transporting ATP synthase activity, rotational mechanism
XHV734_0869	COG2226	methyltransferase
XHV734_0870	COG3300	MHYT domain
XHV734_0870	COG5001	Diguanylate cyclase
XHV734_0871	COG0308	aminopeptidase N
XHV734_0882	COG3284	Transcriptional regulator
XHV734_0883	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XHV734_0884	COG1077	Cell shape determining protein MreB Mrl
XHV734_0885	COG1792	Involved in formation and maintenance of cell shape
XHV734_0886	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
XHV734_0888	COG0772	Belongs to the SEDS family
XHV734_0890	COG2951	lytic endotransglycosylase activity
XHV734_0891	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XHV734_0893	COG1686	Belongs to the peptidase S11 family
XHV734_0896	COG0321	lipoyl(octanoyl) transferase activity
XHV734_0897	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
XHV734_0902	COG1051	belongs to the nudix hydrolase family
XHV734_0902	COG1056	cytidyltransferase-related domain
XHV734_0909	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
XHV734_0910	COG0673	inositol 2-dehydrogenase activity
XHV734_0911	COG2823	Periplasmic or secreted lipoprotein
XHV734_0912	COG4251	negative regulation of phosphorylation
XHV734_0913	COG0784	Response regulator, receiver
XHV734_0914	COG4191	Histidine kinase
XHV734_0915	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XHV734_0916	COG1028	Short-chain dehydrogenase reductase Sdr
XHV734_0925	COG1459	type II secretion system
XHV734_0930	COG3156	type II secretion system protein K
XHV734_0938	COG3250	beta-galactosidase activity
XHV734_0941	COG2188	Transcriptional regulator
XHV734_0943	COG1609	Transcriptional regulator
XHV734_0944	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XHV734_0945	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
XHV734_0953	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
XHV734_0955	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
XHV734_0957	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XHV734_0960	COG0218	Necessary for normal cell division and for the maintenance of normal septation
XHV734_0962	COG2205	protein histidine kinase activity
XHV734_0966	COG3920	Histidine kinase
XHV734_0969	COG3791	Glutathione-dependent formaldehyde-activating
XHV734_0972	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XHV734_0974	COG0697	spore germination
XHV734_0986	COG0402	S-adenosylhomocysteine deaminase activity
XHV734_0990	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XHV734_0992	COG0726	polysaccharide deacetylase
XHV734_0993	COG4773	Receptor
XHV734_1017	COG2211	Major facilitator Superfamily
XHV734_1018	COG1609	Transcriptional regulator
XHV734_1019	COG1028	Short-chain dehydrogenase reductase Sdr
XHV734_1020	COG2851	Citrate transporter
XHV734_1023	COG0642	Histidine kinase
XHV734_1026	COG2197	response regulator
XHV734_1029	COG4191	Histidine kinase
XHV734_1033	COG0280	phosphate acetyltransferase
XHV734_1033	COG0281	malic enzyme
XHV734_1039	COG1560	Kdo2-lipid A biosynthetic process
XHV734_1040	COG1519	Transferase
XHV734_1041	COG1538	Outer membrane efflux protein
XHV734_1042	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XHV734_1046	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
XHV734_1047	COG0066	3-isopropylmalate dehydratase activity
XHV734_1048	COG2226	methyltransferase
XHV734_1049	COG0473	3-isopropylmalate dehydrogenase activity
XHV734_1050	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
XHV734_1054	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
XHV734_1055	COG0405	Gamma-glutamyltransferase
XHV734_1056	COG0840	transmembrane signaling receptor activity
XHV734_1057	COG4946	Tricorn protease homolog
XHV734_1057	COG1506	peptidase
XHV734_1057	COG0823	Involved in the tonB-independent uptake of proteins
XHV734_1060	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
XHV734_1061	COG3710	Transcriptional regulator
XHV734_1065	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
XHV734_1068	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
XHV734_1074	COG0563	adenylate kinase activity
XHV734_1075	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XHV734_1077	COG3781	membrane
XHV734_1080	COG0671	phosphoesterase, PA-phosphatase related
XHV734_1082	COG1028	Short-chain dehydrogenase reductase Sdr
XHV734_1086	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XHV734_1087	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XHV734_1093	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XHV734_1094	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
XHV734_1096	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XHV734_1100	COG0352	thiamine-phosphate diphosphorylase activity
XHV734_1101	COG1773	rubredoxin
XHV734_1102	COG2912	Transglutaminase-like superfamily
XHV734_1106	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
XHV734_1111	COG0006	proline dipeptidase activity
XHV734_1112	COG0006	proline dipeptidase activity
XHV734_1115	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XHV734_1117	COG0346	lactoylglutathione lyase activity
XHV734_1118	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
XHV734_1119	COG1561	YicC-like family, N-terminal region
XHV734_1123	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XHV734_1125	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
XHV734_1130	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XHV734_1136	COG0714	Associated with various cellular activities
XHV734_1144	COG1301	dicarboxylic acid transport
XHV734_1147	COG4773	Receptor
XHV734_1148	COG0583	DNA-binding transcription factor activity
XHV734_1149	COG1028	Short-chain dehydrogenase reductase Sdr
XHV734_1151	COG1376	ErfK ybiS ycfS ynhG family protein
XHV734_1155	COG3682	Transcriptional regulator
XHV734_1158	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
XHV734_1159	COG4149	molybdate abc transporter
XHV734_1160	COG0725	ABC transporter, periplasmic molybdate-binding protein
XHV734_1161	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XHV734_1161	COG3453	Protein conserved in bacteria
XHV734_1163	COG3047	cAMP biosynthetic process
XHV734_1167	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
XHV734_1173	COG0469	pyruvate kinase activity
XHV734_1174	COG3588	fructose-bisphosphate aldolase
XHV734_1175	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
XHV734_1178	COG1648	precorrin-2 dehydrogenase activity
XHV734_1178	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XHV734_1182	COG0784	Response regulator, receiver
XHV734_1182	COG2198	Histidine kinase
XHV734_1182	COG2205	protein histidine kinase activity
XHV734_1187	COG0175	sulfate reduction
XHV734_1188	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XHV734_1191	COG2895	sulfate adenylyltransferase (ATP) activity
XHV734_1191	COG0529	Catalyzes the synthesis of activated sulfate
XHV734_1192	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XHV734_1193	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XHV734_1197	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XHV734_1198	COG2272	Belongs to the type-B carboxylesterase lipase family
XHV734_1201	COG4948	Mandelate Racemase Muconate Lactonizing
XHV734_1202	COG3250	beta-galactosidase activity
XHV734_1204	COG1609	Transcriptional regulator
XHV734_1210	COG0471	metal ion transport
XHV734_1210	COG3273	potassium ion transport
XHV734_1211	COG0220	tRNA (guanine-N7-)-methyltransferase activity
XHV734_1224	COG2801	Transposase and inactivated derivatives
XHV734_1225	COG2963	transposase activity
XHV734_1228	COG1238	metal cluster binding
XHV734_1229	COG0840	transmembrane signaling receptor activity
XHV734_1240	COG0189	ligase activity
XHV734_1241	COG0745	RESPONSE REGULATOR receiver
XHV734_1249	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
XHV734_1255	COG0045	succinate-CoA ligase (ADP-forming) activity
XHV734_1256	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
XHV734_1262	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XHV734_1262	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
XHV734_1264	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XHV734_1265	COG0564	pseudouridine synthase activity
XHV734_1268	COG3011	Protein conserved in bacteria
XHV734_1269	COG0840	transmembrane signaling receptor activity
XHV734_1273	COG3387	PFAM Glycoside hydrolase 15-related
XHV734_1274	COG1877	trehalose-phosphatase activity
XHV734_1285	COG4771	TonB-dependent receptor
XHV734_1287	COG0667	Aldo Keto reductase
XHV734_1288	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XHV734_1289	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XHV734_1290	COG1116	anion transmembrane transporter activity
XHV734_1291	COG0542	response to heat
XHV734_1294	COG4206	TonB-dependent receptor
XHV734_1296	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
XHV734_1298	COG0019	diaminopimelate decarboxylase activity
XHV734_1299	COG4264	IucA IucC family
XHV734_1301	COG4264	IucA IucC family
XHV734_1303	COG4772	TonB-dependent receptor
XHV734_1305	COG4651	solute:proton antiporter activity
XHV734_1305	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XHV734_1313	COG0488	(ABC) transporter
XHV734_1323	COG0477	Major facilitator Superfamily
XHV734_1327	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
XHV734_1334	COG2255	four-way junction helicase activity
XHV734_1335	COG0824	Thioesterase
XHV734_1337	COG0848	biopolymer transport protein
XHV734_1340	COG2885	chlorophyll binding
XHV734_1342	COG0602	queuosine metabolic process
XHV734_1343	COG0667	Aldo Keto reductase
XHV734_1356	COG4983	Phage plasmid primase, P4 family domain protein
XHV734_1361	COG0582	viral genome integration into host DNA
XHV734_1362	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
XHV734_1364	COG3920	Histidine kinase
XHV734_1376	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XHV734_1381	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
XHV734_1382	COG0336	Belongs to the RNA methyltransferase TrmD family
XHV734_1384	COG0534	Mate efflux family protein
XHV734_1389	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
XHV734_1391	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
XHV734_1395	COG0840	transmembrane signaling receptor activity
XHV734_1400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XHV734_1404	COG0583	DNA-binding transcription factor activity
XHV734_1405	COG1301	dicarboxylic acid transport
XHV734_1406	COG4948	Mandelate Racemase Muconate Lactonizing
XHV734_1407	COG3250	beta-galactosidase activity
XHV734_1408	COG3867	Arabinogalactan endo-beta-1,4-galactanase
XHV734_1413	COG1960	acyl-CoA dehydrogenase activity
XHV734_1414	COG1024	Enoyl-CoA hydratase
XHV734_1415	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
XHV734_1431	COG0457	Tetratricopeptide repeat
XHV734_1433	COG1024	Enoyl-CoA hydratase
XHV734_1433	COG1250	3-hydroxyacyl-CoA dehydrogenase
XHV734_1436	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XHV734_1441	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
XHV734_1442	COG1381	Involved in DNA repair and RecF pathway recombination
XHV734_1447	COG2954	triphosphatase activity
XHV734_1448	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
XHV734_1449	COG1233	COG1233 Phytoene dehydrogenase and related
XHV734_1450	COG3046	protein related to deoxyribodipyrimidine photolyase
XHV734_1451	COG1472	Belongs to the glycosyl hydrolase 3 family
XHV734_1452	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
XHV734_1453	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
XHV734_1454	COG1278	Cold shock
XHV734_1455	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XHV734_1457	COG1201	RNA secondary structure unwinding
XHV734_1458	COG1793	dna ligase
XHV734_1459	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XHV734_1459	COG1793	dna ligase
XHV734_1467	COG0183	Belongs to the thiolase family
XHV734_1473	COG1451	nucleotide metabolic process
XHV734_1474	COG5487	UPF0391 membrane protein
XHV734_1477	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XHV734_1487	COG1047	Peptidyl-prolyl cis-trans
XHV734_1489	COG2824	Alkylphosphonate utilization operon protein PhnA
XHV734_1493	COG1902	pentaerythritol trinitrate reductase activity
XHV734_1494	COG2814	Major facilitator Superfamily
XHV734_1501	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
XHV734_1501	COG0392	lysyltransferase activity
XHV734_1503	COG0251	oxidation-reduction process
XHV734_1508	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XHV734_1514	COG1595	DNA-templated transcription, initiation
XHV734_1518	COG2878	Part of a membrane complex involved in electron transport
XHV734_1520	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XHV734_1520	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XHV734_1525	COG3846	protein secretion by the type IV secretion system
XHV734_1528	COG3451	type IV secretory pathway VirB4
XHV734_1530	COG3838	Conjugal transfer protein Trbc
XHV734_1531	COG4962	Type ii secretion system protein e
XHV734_1535	COG0583	DNA-binding transcription factor activity
XHV734_1536	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XHV734_1537	COG2814	Major facilitator Superfamily
XHV734_1538	COG0583	DNA-binding transcription factor activity
XHV734_1539	COG1028	Short-chain dehydrogenase reductase Sdr
XHV734_1541	COG0625	glutathione transferase activity
XHV734_1550	COG1192	Involved in chromosome partitioning
XHV734_1558	COG5489	Protein of unknown function (DUF736)
XHV734_1559	COG1475	DNA binding
XHV734_1561	COG3344	reverse transcriptase
XHV734_1566	COG4804	nuclease activity
XHV734_1570	COG1131	(ABC) transporter
XHV734_1572	COG0346	lactoylglutathione lyase activity
XHV734_1573	COG0833	amino acid
XHV734_1574	COG2040	homocysteine
XHV734_1578	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XHV734_1585	COG1695	Transcriptional regulator
XHV734_1592	COG1981	membrane
XHV734_1594	COG0825	malonyl-CoA metabolic process
XHV734_1597	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XHV734_1598	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XHV734_1599	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XHV734_1600	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XHV734_1603	COG0750	zinc metalloprotease
XHV734_1604	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
XHV734_1605	COG0575	Belongs to the CDS family
XHV734_1606	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
XHV734_1608	COG0528	UMP kinase activity
XHV734_1610	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
XHV734_1611	COG0052	Belongs to the universal ribosomal protein uS2 family
XHV734_1619	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
XHV734_1622	COG1393	Belongs to the ArsC family
XHV734_1623	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XHV734_1625	COG0367	asparagine synthase
XHV734_1627	COG4774	siderophore transport
XHV734_1639	COG1566	PFAM secretion protein HlyD family protein
XHV734_1640	COG2814	Major facilitator Superfamily
XHV734_1650	COG0339	signal peptide processing
XHV734_1652	COG0386	Belongs to the glutathione peroxidase family
XHV734_1659	COG0288	reversible hydration of carbon dioxide
XHV734_1667	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
XHV734_1668	COG0084	hydrolase, TatD family'
XHV734_1671	COG1960	acyl-CoA dehydrogenase activity
XHV734_1674	COG0367	asparagine synthase
XHV734_1677	COG0305	Participates in initiation and elongation during chromosome replication
XHV734_1679	COG0415	Belongs to the DNA photolyase family
XHV734_1683	COG3118	belongs to the thioredoxin family
XHV734_1685	COG0495	leucyl-tRNA aminoacylation
XHV734_1688	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
XHV734_1693	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
XHV734_1699	COG3164	Protein of unknown function
XHV734_1701	COG0312	modulator of DNA gyrase
XHV734_1703	COG0312	modulator of DNA gyrase
XHV734_1705	COG4104	PAAR repeat-containing protein
XHV734_1706	COG0142	geranyltranstransferase activity
XHV734_1707	COG1722	exodeoxyribonuclease VII activity
XHV734_1708	COG0037	tRNA processing
XHV734_1709	COG1785	Belongs to the alkaline phosphatase family
XHV734_1710	COG1301	dicarboxylic acid transport
XHV734_1713	COG0791	NLP P60 protein
XHV734_1714	COG0791	NLP P60 protein
XHV734_1715	COG1047	Peptidyl-prolyl cis-trans
XHV734_1716	COG2311	Membrane
XHV734_1717	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XHV734_1724	COG3590	peptidase
XHV734_1730	COG0489	protein tyrosine kinase activity
XHV734_1731	COG0717	Belongs to the dCTP deaminase family
XHV734_1737	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XHV734_1740	COG3039	Transposase
XHV734_1741	COG1472	Belongs to the glycosyl hydrolase 3 family
XHV734_1747	COG0494	nUDIX hydrolase
XHV734_1749	COG0433	COG0433 Predicted ATPase
XHV734_1751	COG0688	phosphatidylethanolamine metabolic process
XHV734_1753	COG2890	protein-(glutamine-N5) methyltransferase activity
XHV734_1756	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XHV734_1757	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XHV734_1760	COG0101	tRNA pseudouridine synthase activity
XHV734_1761	COG0135	phosphoribosylanthranilate isomerase activity
XHV734_1763	COG0133	tryptophan synthase activity
XHV734_1765	COG0159	tryptophan synthase activity
XHV734_1768	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XHV734_1778	COG4221	oxidoreductase activity
XHV734_1781	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XHV734_1783	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XHV734_1784	COG0649	NAD binding
XHV734_1785	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
XHV734_1786	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XHV734_1788	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
XHV734_1790	COG0839	Belongs to the complex I subunit 6 family
XHV734_1794	COG1007	ATP synthesis coupled electron transport
XHV734_1796	COG0779	Required for maturation of 30S ribosomal subunits
XHV734_1797	COG0195	Participates in both transcription termination and antitermination
XHV734_1800	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
XHV734_1801	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
XHV734_1802	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
XHV734_1810	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XHV734_1811	COG1028	Short-chain dehydrogenase reductase Sdr
XHV734_1812	COG2095	MarC family integral membrane protein
XHV734_1814	COG1611	Belongs to the LOG family
XHV734_1824	COG3505	Type IV secretory pathway VirD4
XHV734_1828	COG2948	multi-organism process
XHV734_1832	COG3702	type iv secretory pathway
XHV734_1842	COG2963	transposase activity
XHV734_1843	COG2801	Transposase and inactivated derivatives
XHV734_1844	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
XHV734_1845	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
XHV734_1849	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
XHV734_1850	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XHV734_1850	COG0072	phenylalanine-tRNA ligase activity
XHV734_1859	COG0438	transferase activity, transferring glycosyl groups
XHV734_1860	COG0438	transferase activity, transferring glycosyl groups
XHV734_1862	COG0438	transferase activity, transferring glycosyl groups
XHV734_1868	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XHV734_1869	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XHV734_1870	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XHV734_1876	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
XHV734_1878	COG1960	acyl-CoA dehydrogenase activity
XHV734_1880	COG3040	lipid binding
XHV734_1884	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XHV734_1893	COG1194	a g-specific adenine glycosylase
XHV734_1894	COG0552	protein localization to endoplasmic reticulum
XHV734_1896	COG3938	Belongs to the proline racemase family
XHV734_1897	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XHV734_1900	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XHV734_1902	COG0006	proline dipeptidase activity
XHV734_1905	COG0531	amino acid
XHV734_1925	COG2801	Transposase and inactivated derivatives
XHV734_1926	COG2963	transposase activity
XHV734_1928	COG0742	ribosomal rna small subunit methyltransferase
XHV734_1931	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XHV734_1932	COG0405	Gamma-glutamyltransferase
XHV734_1933	COG3291	Pkd domain containing protein
XHV734_1944	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
XHV734_1946	COG1862	Preprotein translocase
XHV734_1948	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XHV734_1959	COG2963	transposase activity
XHV734_1964	COG2963	transposase activity
XHV734_1965	COG2801	Transposase and inactivated derivatives
XHV734_1969	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XHV734_1969	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XHV734_1971	COG1105	Belongs to the carbohydrate kinase PfkB family
XHV734_1972	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XHV734_1972	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
XHV734_1973	COG1609	Transcriptional regulator
XHV734_1974	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XHV734_1975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XHV734_1977	COG2902	Dehydrogenase
XHV734_1986	COG0604	alcohol dehydrogenase
XHV734_1986	COG3321	synthase
XHV734_1988	COG1902	pentaerythritol trinitrate reductase activity
XHV734_1992	COG0300	oxidoreductase activity
XHV734_1993	COG0604	alcohol dehydrogenase
XHV734_1996	COG0477	Major facilitator Superfamily
XHV734_1998	COG5002	protein histidine kinase activity
XHV734_1998	COG2205	protein histidine kinase activity
XHV734_1998	COG0784	Response regulator, receiver
XHV734_1999	COG2733	membrane
XHV734_2001	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XHV734_2003	COG2223	nitrite transmembrane transporter activity
XHV734_2005	COG0243	molybdopterin cofactor binding
XHV734_2015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XHV734_2016	COG0174	glutamine synthetase
XHV734_2017	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
XHV734_2024	COG3842	ATPase activity
XHV734_2025	COG1176	ABC-type spermidine putrescine transport system, permease component I
XHV734_2026	COG1177	transmembrane transport
XHV734_2030	COG1012	belongs to the aldehyde dehydrogenase family
XHV734_2034	COG4535	Mg2 and Co2 transporter CorC
XHV734_2038	COG1702	phosphate starvation-inducible protein PhoH
XHV734_2040	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XHV734_2043	COG0741	lytic transglycosylase activity
XHV734_2044	COG0723	plastoquinol--plastocyanin reductase activity
XHV734_2045	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
XHV734_2046	COG2857	Cytochrome c1
XHV734_2048	COG0625	glutathione transferase activity
XHV734_2049	COG2969	positive regulation of protein catabolic process
XHV734_2051	COG1201	RNA secondary structure unwinding
XHV734_2054	COG0840	transmembrane signaling receptor activity
XHV734_2055	COG0835	chemotaxis
XHV734_2056	COG2199	diguanylate cyclase activity
XHV734_2062	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XHV734_2065	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XHV734_2066	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
XHV734_2066	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XHV734_2068	COG0860	N-Acetylmuramoyl-L-alanine amidase
XHV734_2069	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
XHV734_2073	COG1028	Short-chain dehydrogenase reductase Sdr
XHV734_2074	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XHV734_2075	COG0501	Belongs to the peptidase M48B family
XHV734_2076	COG5001	Diguanylate cyclase
XHV734_2076	COG3300	MHYT domain
XHV734_2077	COG2081	HI0933 family
XHV734_2078	COG4681	YaeQ
XHV734_2079	COG1671	Belongs to the UPF0178 family
XHV734_2082	COG0625	glutathione transferase activity
XHV734_2085	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
XHV734_2086	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
XHV734_2087	COG0513	Belongs to the DEAD box helicase family
XHV734_2088	COG0488	(ABC) transporter
XHV734_2089	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
XHV734_2091	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
XHV734_2092	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
XHV734_2093	COG0259	pyridoxamine-phosphate oxidase activity
XHV734_2096	COG1842	Phage shock protein A
XHV734_2101	COG0754	glutathionylspermidine amidase activity
XHV734_2102	COG2814	Major facilitator Superfamily
XHV734_2117	COG0531	amino acid
XHV734_2118	COG2197	response regulator
XHV734_2121	COG1113	amino acid transport
XHV734_2123	COG1271	oxidase subunit
XHV734_2124	COG1294	oxidase, subunit
XHV734_2126	COG2239	Acts as a magnesium transporter
XHV734_2127	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XHV734_2128	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XHV734_2133	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
XHV734_2137	COG1137	ATPase activity
XHV734_2138	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
XHV734_2140	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
XHV734_2142	COG0271	Belongs to the BolA IbaG family
XHV734_2143	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
XHV734_2147	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
XHV734_2150	COG0628	permease
XHV734_2154	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XHV734_2156	COG0483	inositol monophosphate 1-phosphatase activity
XHV734_2159	COG5001	Diguanylate cyclase
XHV734_2159	COG3300	MHYT domain
XHV734_2160	COG1509	lysine 2,3-aminomutase activity
XHV734_2163	COG0402	S-adenosylhomocysteine deaminase activity
XHV734_2164	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XHV734_2176	COG4302	ethanolamine ammonia-lyase activity
XHV734_2177	COG4303	Ethanolamine ammonia lyase large subunit
XHV734_2180	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XHV734_2184	COG2166	iron-sulfur cluster assembly
XHV734_2188	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
XHV734_2189	COG0137	argininosuccinate synthase activity
XHV734_2190	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XHV734_2191	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XHV734_2194	COG0165	Argininosuccinate lyase
XHV734_2197	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
XHV734_2206	COG1294	oxidase, subunit
XHV734_2209	COG4988	ABC transporter
XHV734_2210	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
XHV734_2217	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
XHV734_2222	COG0436	Aminotransferase
XHV734_2223	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XHV734_2226	COG1187	pseudouridine synthase activity
XHV734_2227	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
XHV734_2228	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
XHV734_2229	COG2350	Protein conserved in bacteria
XHV734_2234	COG1653	transport
XHV734_2235	COG1175	transmembrane transport
XHV734_2236	COG0395	ABC-type sugar transport system, permease component
XHV734_2241	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XHV734_2242	COG2957	Belongs to the agmatine deiminase family
XHV734_2247	COG0776	regulation of translation
XHV734_2249	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
XHV734_2250	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XHV734_2252	COG1210	Utp--glucose-1-phosphate uridylyltransferase
XHV734_2253	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XHV734_2253	COG0475	glutathione-regulated potassium exporter activity
XHV734_2255	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
XHV734_2264	COG3039	Transposase
XHV734_2266	COG2801	Transposase and inactivated derivatives
XHV734_2271	COG1914	H( )-stimulated, divalent metal cation uptake system
XHV734_2274	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
XHV734_2276	COG0668	transmembrane transport
XHV734_2281	COG1028	Short-chain dehydrogenase reductase Sdr
XHV734_2283	COG1183	phosphatidylcholine synthase activity
XHV734_2285	COG3243	poly(R)-hydroxyalkanoic acid synthase
XHV734_2291	COG2183	response to ionizing radiation
XHV734_2292	COG0784	Response regulator, receiver
XHV734_2292	COG5002	protein histidine kinase activity
XHV734_2292	COG2205	protein histidine kinase activity
XHV734_2295	COG0582	viral genome integration into host DNA
XHV734_2312	COG0800	Aldolase
XHV734_2313	COG0129	dihydroxy-acid dehydratase activity
XHV734_2314	COG0363	glucosamine-6-phosphate deaminase activity
XHV734_2315	COG0837	glucose binding
XHV734_2316	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XHV734_2318	COG0354	folic acid binding
XHV734_2320	COG2009	succinate dehydrogenase
XHV734_2321	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
XHV734_2323	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
XHV734_2324	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
XHV734_2326	COG4591	ABC-type transport system involved in lipoprotein release permease component
XHV734_2327	COG1136	(ABC) transporter
XHV734_2330	COG0811	peptide transport
XHV734_2332	COG1132	(ABC) transporter
XHV734_2333	COG1663	tetraacyldisaccharide 4'-kinase activity
XHV734_2334	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
XHV734_2335	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
XHV734_2337	COG0322	excinuclease ABC activity
XHV734_2338	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XHV734_2339	COG0582	viral genome integration into host DNA
XHV734_2341	COG1396	sequence-specific DNA binding
XHV734_2342	COG0583	DNA-binding transcription factor activity
XHV734_2348	COG1074	ATP-dependent DNA helicase activity
XHV734_2361	COG2963	transposase activity
XHV734_2362	COG2801	Transposase and inactivated derivatives
XHV734_2364	COG2801	Transposase and inactivated derivatives
XHV734_2365	COG2963	transposase activity
XHV734_2368	COG4221	oxidoreductase activity
XHV734_2370	COG3830	Belongs to the UPF0237 family
XHV734_2370	COG0560	Phosphoserine phosphatase
XHV734_2378	COG2003	Belongs to the UPF0758 family
XHV734_2419	COG0270	DNA (cytosine-5-)-methyltransferase activity
XHV734_2422	COG2963	transposase activity
XHV734_2424	COG2963	transposase activity
XHV734_2425	COG2801	Transposase and inactivated derivatives
XHV734_2430	COG0464	growth
XHV734_2432	COG2977	Belongs to the P-Pant transferase superfamily
XHV734_2433	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
XHV734_2437	COG1054	Belongs to the UPF0176 family
XHV734_2439	COG1530	ribonuclease E activity
XHV734_2441	COG0428	transporter
XHV734_2458	COG0428	transporter
XHV734_2460	COG2154	pterin-4-alpha-carbinolamine dehydratase
XHV734_2482	COG2963	transposase activity
XHV734_2483	COG2801	Transposase and inactivated derivatives
XHV734_2484	COG0840	transmembrane signaling receptor activity
XHV734_2491	COG2197	response regulator
XHV734_2492	COG4191	Histidine kinase
XHV734_2493	COG3781	membrane
XHV734_2500	COG4191	Histidine kinase
XHV734_2500	COG0784	Response regulator, receiver
XHV734_2518	COG5001	Diguanylate cyclase
XHV734_2521	COG3685	Protein conserved in bacteria
XHV734_2524	COG0579	oxidoreductase
XHV734_2526	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XHV734_2528	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
XHV734_2532	COG0243	molybdopterin cofactor binding
XHV734_2534	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XHV734_2535	COG2223	nitrite transmembrane transporter activity
XHV734_2538	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XHV734_2540	COG1648	precorrin-2 dehydrogenase activity
XHV734_2540	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XHV734_2542	COG0746	molybdenum cofactor guanylyltransferase activity
XHV734_2543	COG0303	'Molybdopterin
XHV734_2545	COG0708	Exodeoxyribonuclease III
XHV734_2547	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XHV734_2548	COG0303	'Molybdopterin
XHV734_2549	COG1160	GTP binding
XHV734_2550	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XHV734_2554	COG0820	rRNA (adenine-C2-)-methyltransferase activity
XHV734_2557	COG1024	Enoyl-CoA hydratase
XHV734_2557	COG1250	3-hydroxyacyl-CoA dehydrogenase
XHV734_2558	COG0183	Belongs to the thiolase family
XHV734_2559	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
XHV734_2560	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
XHV734_2564	COG1674	ftsk spoiiie
XHV734_2565	COG0492	ferredoxin-NADP+ reductase activity
XHV734_2568	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
XHV734_2570	COG0542	response to heat
XHV734_2574	COG0482	sulfurtransferase activity
XHV734_2584	COG4191	Histidine kinase
XHV734_2588	COG0835	chemotaxis
XHV734_2588	COG0784	Response regulator, receiver
XHV734_2590	COG1558	bacterial-type flagellum-dependent cell motility
XHV734_2591	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
XHV734_2593	COG4787	bacterial-type flagellum-dependent cell motility
XHV734_2598	COG1705	Flagellar rod assembly protein muramidase FlgJ
XHV734_2598	COG3951	Flagellar rod assembly protein muramidase FlgJ
XHV734_2602	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XHV734_2603	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
XHV734_2609	COG2201	protein-glutamate methylesterase activity
XHV734_2613	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XHV734_2614	COG1028	Short-chain dehydrogenase reductase Sdr
XHV734_2615	COG1028	Short-chain dehydrogenase reductase Sdr
XHV734_2625	COG1677	Flagellar hook-basal body complex protein FliE
XHV734_2635	COG3190	flagellar
XHV734_2639	COG5001	Diguanylate cyclase
XHV734_2639	COG3300	MHYT domain
XHV734_2651	COG2198	Histidine kinase
XHV734_2651	COG0784	Response regulator, receiver
XHV734_2651	COG0643	Histidine kinase
XHV734_2655	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
XHV734_2657	COG1192	Involved in chromosome partitioning
XHV734_2658	COG0835	chemotaxis
XHV734_2660	COG0745	RESPONSE REGULATOR receiver
XHV734_2661	COG2198	Histidine kinase
XHV734_2661	COG0643	Histidine kinase
XHV734_2663	COG0840	transmembrane signaling receptor activity
XHV734_2665	COG0840	transmembrane signaling receptor activity
XHV734_2665	COG0840	transmembrane signaling receptor activity
XHV734_2666	COG0840	transmembrane signaling receptor activity
XHV734_2667	COG0840	transmembrane signaling receptor activity
XHV734_2669	COG0840	transmembrane signaling receptor activity
XHV734_2671	COG0840	transmembrane signaling receptor activity
XHV734_2673	COG0840	transmembrane signaling receptor activity
XHV734_2674	COG0840	transmembrane signaling receptor activity
XHV734_2675	COG0840	transmembrane signaling receptor activity
XHV734_2678	COG0835	chemotaxis
XHV734_2680	COG0840	transmembrane signaling receptor activity
XHV734_2684	COG2201	protein-glutamate methylesterase activity
XHV734_2687	COG2267	carboxylic ester hydrolase activity
XHV734_2694	COG0784	Response regulator, receiver
XHV734_2694	COG2198	Histidine kinase
XHV734_2694	COG2205	protein histidine kinase activity
XHV734_2695	COG2205	protein histidine kinase activity
XHV734_2695	COG0784	Response regulator, receiver
XHV734_2695	COG2198	Histidine kinase
XHV734_2697	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
XHV734_2698	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
XHV734_2699	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
XHV734_2704	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
XHV734_2706	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XHV734_2707	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
XHV734_2709	COG0505	Belongs to the CarA family
XHV734_2711	COG2258	MOSC domain
XHV734_2712	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XHV734_2716	COG1024	Enoyl-CoA hydratase
XHV734_2719	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XHV734_2724	COG0277	FAD linked oxidase domain protein
XHV734_2726	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XHV734_2731	COG0531	amino acid
XHV734_2732	COG0531	amino acid
XHV734_2737	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
XHV734_2741	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
XHV734_2741	COG0140	phosphoribosyl-ATP diphosphatase activity
XHV734_2742	COG0107	imidazoleglycerol-phosphate synthase activity
XHV734_2745	COG0131	Imidazoleglycerol-phosphate dehydratase
XHV734_2745	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
XHV734_2746	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XHV734_2747	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
XHV734_2748	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
XHV734_2753	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XHV734_2759	COG0527	aspartate kinase activity
XHV734_2759	COG0460	homoserine dehydrogenase
XHV734_2761	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
XHV734_2773	COG0726	polysaccharide deacetylase
XHV734_2773	COG1649	PFAM Uncharacterised BCR, COG1649
XHV734_2775	COG2801	Transposase and inactivated derivatives
XHV734_2776	COG2963	transposase activity
XHV734_2786	COG2963	transposase activity
XHV734_2787	COG2801	Transposase and inactivated derivatives
XHV734_2787	COG2801	Transposase and inactivated derivatives
XHV734_2799	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XHV734_2801	COG3621	Patatin-like phospholipase
XHV734_2810	COG1012	belongs to the aldehyde dehydrogenase family
XHV734_2813	COG0167	dihydroorotate dehydrogenase activity
XHV734_2814	COG0812	UDP-N-acetylmuramate dehydrogenase activity
XHV734_2815	COG0697	spore germination
XHV734_2817	COG0671	phosphoesterase, PA-phosphatase related
XHV734_2818	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
XHV734_2820	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
XHV734_2822	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XHV734_2823	COG2203	Gaf domain
XHV734_2823	COG3706	GGDEF domain
XHV734_2823	COG4251	negative regulation of phosphorylation
XHV734_2823	COG5001	Diguanylate cyclase
XHV734_2825	COG1472	Belongs to the glycosyl hydrolase 3 family
XHV734_2830	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
XHV734_2831	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
XHV734_2832	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
XHV734_2833	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XHV734_2837	COG0860	N-Acetylmuramoyl-L-alanine amidase
XHV734_2841	COG0477	Major facilitator Superfamily
XHV734_2842	COG2115	Belongs to the xylose isomerase family
XHV734_2843	COG1070	Carbohydrate kinase
XHV734_2845	COG1501	Belongs to the glycosyl hydrolase 31 family
XHV734_2852	COG0800	Aldolase
XHV734_2853	COG4948	Mandelate Racemase Muconate Lactonizing
XHV734_2857	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
XHV734_2860	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XHV734_2863	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XHV734_2864	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
XHV734_2867	COG0352	thiamine-phosphate diphosphorylase activity
XHV734_2867	COG0351	phosphomethylpyrimidine kinase
XHV734_2871	COG0583	DNA-binding transcription factor activity
XHV734_2872	COG1741	Belongs to the pirin family
XHV734_2876	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
XHV734_2877	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
XHV734_2878	COG2137	regulation of response to DNA damage stimulus
XHV734_2879	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
XHV734_2881	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XHV734_2883	COG4771	TonB-dependent receptor
XHV734_2884	COG1546	Belongs to the CinA family
XHV734_2885	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
XHV734_2887	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
XHV734_2888	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
XHV734_2890	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
XHV734_2892	COG1534	Rna-binding protein
XHV734_2895	COG1238	metal cluster binding
XHV734_2896	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XHV734_2897	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
XHV734_2898	COG2840	Smr protein MutS2
XHV734_2900	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
XHV734_2901	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
XHV734_2903	COG0148	phosphopyruvate hydratase activity
XHV734_2906	COG0504	CTP synthase activity
XHV734_2915	COG1253	flavin adenine dinucleotide binding
XHV734_2918	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XHV734_2920	COG0477	Major facilitator Superfamily
XHV734_2923	COG1132	(ABC) transporter
XHV734_2924	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
XHV734_2929	COG0438	transferase activity, transferring glycosyl groups
XHV734_2930	COG0297	glycogen (starch) synthase activity
XHV734_2931	COG2264	protein methyltransferase activity
XHV734_2937	COG2244	polysaccharide biosynthetic process
XHV734_2948	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XHV734_2950	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
XHV734_2952	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XHV734_2962	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XHV734_2970	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
XHV734_2971	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XHV734_2972	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XHV734_2973	COG2080	2 iron, 2 sulfur cluster binding
XHV734_2974	COG4251	negative regulation of phosphorylation
XHV734_2974	COG5001	Diguanylate cyclase
XHV734_2974	COG3706	GGDEF domain
XHV734_2974	COG2203	Gaf domain
XHV734_2979	COG0629	single-stranded DNA binding
XHV734_2980	COG0142	geranyltranstransferase activity
XHV734_2984	COG0527	aspartate kinase activity
XHV734_2985	COG0384	phenazine biosynthesis protein PhzF
XHV734_2986	COG0384	phenazine biosynthesis protein PhzF
XHV734_2988	COG1764	response to oxidative stress
XHV734_2990	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
XHV734_2991	COG1678	Uncharacterized ACR, COG1678
XHV734_2992	COG0519	Catalyzes the synthesis of GMP from XMP
XHV734_2997	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
XHV734_3001	COG4942	peptidase
XHV734_3008	COG1959	2 iron, 2 sulfur cluster binding
XHV734_3009	COG0719	Fe-S assembly protein
XHV734_3010	COG0396	ATPase activity
XHV734_3011	COG0719	Fe-S assembly protein
XHV734_3012	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XHV734_3014	COG0456	acetyltransferase
XHV734_3016	COG4774	siderophore transport
XHV734_3017	COG3128	pkhd-type hydroxylase
XHV734_3022	COG1477	protein flavinylation
XHV734_3023	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XHV734_3026	COG1555	photosystem II stabilization
XHV734_3027	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XHV734_3029	COG3178	'Phosphotransferase
XHV734_3030	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XHV734_3037	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
XHV734_3039	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
XHV734_3040	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
XHV734_3041	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XHV734_3042	COG3115	cell septum assembly
XHV734_3047	COG0316	Belongs to the HesB IscA family
XHV734_3048	COG0017	Asparaginyl-tRNA synthetase
XHV734_3051	COG2808	Putative FMN-binding domain
XHV734_3052	COG0288	reversible hydration of carbon dioxide
XHV734_3056	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XHV734_3057	COG2925	Exonuclease
XHV734_3060	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
XHV734_3062	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
XHV734_3064	COG0488	(ABC) transporter
XHV734_3073	COG1024	Enoyl-CoA hydratase
XHV734_3075	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
XHV734_3079	COG0659	secondary active sulfate transmembrane transporter activity
XHV734_3084	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XHV734_3085	COG0573	inorganic phosphate transmembrane transporter activity
XHV734_3086	COG0581	inorganic phosphate transmembrane transporter activity
XHV734_3088	COG0704	Plays a role in the regulation of phosphate uptake
XHV734_3091	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XHV734_3094	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XHV734_3096	COG0557	exoribonuclease II activity
XHV734_3099	COG3039	Transposase
XHV734_3100	COG1960	acyl-CoA dehydrogenase activity
XHV734_3101	COG2226	methyltransferase
XHV734_3107	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XHV734_3112	COG2900	Belongs to the SlyX family
XHV734_3116	COG0386	Belongs to the glutathione peroxidase family
XHV734_3118	COG1725	Transcriptional regulator
XHV734_3119	COG1131	(ABC) transporter
XHV734_3125	COG1253	flavin adenine dinucleotide binding
XHV734_3129	COG2850	peptidyl-arginine hydroxylation
XHV734_3136	COG1132	(ABC) transporter
XHV734_3137	COG0583	DNA-binding transcription factor activity
XHV734_3138	COG2274	protein secretion by the type I secretion system
XHV734_3144	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
XHV734_3147	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XHV734_3148	COG1420	regulation of RNA biosynthetic process
XHV734_3149	COG0497	DNA recombination
XHV734_3151	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XHV734_3154	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
XHV734_3163	COG3039	Transposase
XHV734_3173	COG3706	GGDEF domain
XHV734_3179	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XHV734_3182	COG0583	DNA-binding transcription factor activity
XHV734_3184	COG2155	Conserved Protein
XHV734_3196	COG1132	(ABC) transporter
XHV734_3198	COG0475	glutathione-regulated potassium exporter activity
XHV734_3202	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XHV734_3208	COG1187	pseudouridine synthase activity
XHV734_3209	COG5002	protein histidine kinase activity
XHV734_3209	COG5001	Diguanylate cyclase
XHV734_3211	COG1595	DNA-templated transcription, initiation
XHV734_3235	COG1404	Belongs to the peptidase S8 family
XHV734_3237	COG1404	Belongs to the peptidase S8 family
XHV734_3238	COG0667	Aldo Keto reductase
XHV734_3239	COG2814	Major facilitator Superfamily
XHV734_3240	COG0583	DNA-binding transcription factor activity
XHV734_3246	COG0667	Aldo Keto reductase
XHV734_3247	COG1309	transcriptional regulator
XHV734_3249	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XHV734_3252	COG0735	belongs to the Fur family
XHV734_3253	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XHV734_3258	COG4452	Inner membrane protein CreD
XHV734_3261	COG2205	protein histidine kinase activity
XHV734_3262	COG0745	RESPONSE REGULATOR receiver
XHV734_3263	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
XHV734_3265	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
XHV734_3266	COG3039	Transposase
XHV734_3269	COG2198	Histidine kinase
XHV734_3269	COG0643	Histidine kinase
XHV734_3270	COG0840	transmembrane signaling receptor activity
XHV734_3271	COG0835	chemotaxis
XHV734_3273	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XHV734_3275	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XHV734_3277	COG3590	peptidase
XHV734_3280	COG1515	deoxyribonuclease V activity
XHV734_3281	COG1741	Belongs to the pirin family
XHV734_3285	COG1741	Belongs to the pirin family
XHV734_3286	COG1966	Carbon starvation protein
XHV734_3287	COG2879	small protein
XHV734_3289	COG0784	Response regulator, receiver
XHV734_3289	COG4191	Histidine kinase
XHV734_3290	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
XHV734_3295	COG0840	transmembrane signaling receptor activity
XHV734_3320	COG2189	Belongs to the N(4) N(6)-methyltransferase family
XHV734_3326	COG2003	Belongs to the UPF0758 family
XHV734_3339	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
XHV734_3340	COG0631	protein serine/threonine phosphatase activity
XHV734_3341	COG4245	von Willebrand factor, type A
XHV734_3345	COG3209	COG3209 Rhs family protein
XHV734_3353	COG0210	DNA helicase
XHV734_3354	COG1752	Esterase of the alpha-beta hydrolase superfamily
XHV734_3361	COG0583	DNA-binding transcription factor activity
XHV734_3362	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
XHV734_3365	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
XHV734_3366	COG1605	Chorismate mutase
XHV734_3366	COG0077	Prephenate dehydratase
XHV734_3367	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
XHV734_3368	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XHV734_3370	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
XHV734_3377	COG1228	amidohydrolase
XHV734_3378	COG2986	histidine ammonia-lyase
XHV734_3381	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
XHV734_3384	COG0477	Major facilitator Superfamily
XHV734_3387	COG2205	protein histidine kinase activity
XHV734_3387	COG2198	Histidine kinase
XHV734_3387	COG0784	Response regulator, receiver
XHV734_3388	COG2198	Histidine kinase
XHV734_3388	COG0784	Response regulator, receiver
XHV734_3388	COG2205	protein histidine kinase activity
XHV734_3389	COG2353	YceI-like domain
XHV734_3390	COG3038	cytochrome b561
XHV734_3392	COG1278	Cold shock
XHV734_3394	COG1760	l-serine dehydratase
XHV734_3396	COG0527	aspartate kinase activity
XHV734_3396	COG0460	homoserine dehydrogenase
XHV734_3397	COG0626	cystathionine gamma-synthase activity
XHV734_3398	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XHV734_3400	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
XHV734_3401	COG1272	protein, Hemolysin III
XHV734_3402	COG2982	Protein involved in outer membrane biogenesis
XHV734_3404	COG0516	GMP reductase activity
XHV734_3404	COG0517	IMP dehydrogenase activity
XHV734_3405	COG0463	Glycosyl transferase, family 2
XHV734_3406	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XHV734_3407	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
XHV734_3410	COG4206	TonB-dependent receptor
XHV734_3411	COG1309	transcriptional regulator
XHV734_3413	COG1960	acyl-CoA dehydrogenase activity
XHV734_3420	COG0509	glycine decarboxylation via glycine cleavage system
XHV734_3421	COG0404	The glycine cleavage system catalyzes the degradation of glycine
XHV734_3422	COG1742	UPF0060 membrane protein
XHV734_3423	COG3956	TIGRFAM MazG family protein
XHV734_3424	COG1218	3'(2'),5'-bisphosphate nucleotidase
XHV734_3425	COG0494	nUDIX hydrolase
XHV734_3427	COG1385	rRNA (uridine-N3-)-methyltransferase activity
XHV734_3428	COG0837	glucose binding
XHV734_3431	COG1388	LysM domain
XHV734_3431	COG3858	chitin binding
XHV734_3433	COG3525	Glycosyl hydrolase, family 20, catalytic domain
XHV734_3436	COG1472	Belongs to the glycosyl hydrolase 3 family
XHV734_3439	COG0531	amino acid
XHV734_3441	COG1486	melibiose metabolic process
XHV734_3443	COG3537	Alpha-1,2-mannosidase
XHV734_3446	COG2963	transposase activity
XHV734_3447	COG2801	Transposase and inactivated derivatives
XHV734_3462	COG3142	Participates in the control of copper homeostasis
XHV734_3463	COG1446	asparaginase
XHV734_3464	COG2304	oxidoreductase activity
XHV734_3465	COG1595	DNA-templated transcription, initiation
XHV734_3470	COG2201	protein-glutamate methylesterase activity
XHV734_3471	COG2198	Histidine kinase
XHV734_3471	COG0643	Histidine kinase
XHV734_3471	COG0784	Response regulator, receiver
XHV734_3472	COG0840	transmembrane signaling receptor activity
XHV734_3473	COG0835	chemotaxis
XHV734_3476	COG0189	ligase activity
XHV734_3479	COG1199	ATP-dependent helicase activity
XHV734_3481	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XHV734_3484	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XHV734_3485	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
XHV734_3486	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
XHV734_3490	COG0837	glucose binding
XHV734_3492	COG1643	Atp-dependent helicase
XHV734_3493	COG0783	Belongs to the Dps family
XHV734_3494	COG0514	ATP-dependent DNA helicase (RecQ)
XHV734_3501	COG0840	transmembrane signaling receptor activity
XHV734_3507	COG3534	alpha-L-arabinofuranosidase
XHV734_3513	COG4191	Histidine kinase
XHV734_3513	COG0784	Response regulator, receiver
XHV734_3514	COG2205	protein histidine kinase activity
XHV734_3514	COG3850	Histidine kinase
XHV734_3514	COG3437	response regulator, receiver
XHV734_3514	COG4999	Histidine kinase
XHV734_3515	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XHV734_3516	COG2201	protein-glutamate methylesterase activity
XHV734_3517	COG2205	protein histidine kinase activity
XHV734_3518	COG5507	3-demethylubiquinone-9 3-methyltransferase
XHV734_3520	COG4771	TonB-dependent receptor
XHV734_3526	COG2172	sigma factor antagonist activity
XHV734_3527	COG1366	Belongs to the anti-sigma-factor antagonist family
XHV734_3528	COG1366	Belongs to the anti-sigma-factor antagonist family
XHV734_3530	COG1902	pentaerythritol trinitrate reductase activity
XHV734_3533	COG0326	Molecular chaperone. Has ATPase activity
XHV734_3534	COG2207	Transcriptional regulator
XHV734_3538	COG3152	Membrane
XHV734_3542	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
XHV734_3543	COG1845	cytochrome c oxidase, subunit III
XHV734_3544	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XHV734_3547	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
XHV734_3549	COG0196	riboflavin kinase activity
XHV734_3552	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
XHV734_3553	COG0211	Belongs to the bacterial ribosomal protein bL27 family
XHV734_3555	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
XHV734_3556	COG0824	Thioesterase
XHV734_3558	COG1024	Enoyl-CoA hydratase
XHV734_3559	COG1946	Acyl-CoA thioesterase
XHV734_3561	COG1595	DNA-templated transcription, initiation
XHV734_3564	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
XHV734_3576	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
XHV734_3580	COG2197	response regulator
XHV734_3581	COG4585	Histidine kinase
XHV734_3584	COG2894	cell division
XHV734_3585	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
XHV734_3587	COG5002	protein histidine kinase activity
XHV734_3588	COG0745	RESPONSE REGULATOR receiver
XHV734_3591	COG2194	sulfuric ester hydrolase activity
XHV734_3595	COG2814	Major facilitator Superfamily
XHV734_3596	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XHV734_3596	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XHV734_3598	COG0656	L-ascorbic acid biosynthetic process
XHV734_3600	COG0753	catalase activity
XHV734_3601	COG2207	Transcriptional regulator
XHV734_3601	COG1917	Cupin 2, conserved barrel domain protein
XHV734_3604	COG0823	Involved in the tonB-independent uptake of proteins
XHV734_3604	COG1506	peptidase
XHV734_3607	COG1297	OPT oligopeptide transporter protein
XHV734_3610	COG0587	DNA-directed DNA polymerase activity
XHV734_3623	COG2080	2 iron, 2 sulfur cluster binding
XHV734_3624	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XHV734_3625	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XHV734_3636	COG3537	Alpha-1,2-mannosidase
XHV734_3638	COG1028	Short-chain dehydrogenase reductase Sdr
XHV734_3640	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XHV734_3656	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
XHV734_3660	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
XHV734_3669	COG0330	HflC and HflK could
XHV734_3670	COG0330	HflC and HflK could
XHV734_3675	COG0678	peroxiredoxin activity
XHV734_3677	COG4953	penicillin-binding protein 1C
XHV734_3682	COG2373	Large extracellular alpha-helical protein
XHV734_3692	COG3829	transcription factor binding
XHV734_3695	COG2161	toxin-antitoxin pair type II binding
XHV734_3696	COG4115	mRNA cleavage
XHV734_3700	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XHV734_3701	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
XHV734_3705	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XHV734_3707	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XHV734_3708	COG0333	Belongs to the bacterial ribosomal protein bL32 family
XHV734_3709	COG1399	metal-binding, possibly nucleic acid-binding protein
XHV734_3713	COG0714	Associated with various cellular activities
XHV734_3717	COG0537	adenosine 5'-monophosphoramidase activity
XHV734_3719	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
XHV734_3723	COG0218	Necessary for normal cell division and for the maintenance of normal septation
XHV734_3736	COG1122	ATPase activity
XHV734_3745	COG1401	restriction endodeoxyribonuclease activity
XHV734_3751	COG0314	molybdopterin synthase activity
XHV734_3752	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
XHV734_3753	COG0315	cyclic pyranopterin monophosphate synthase activity
XHV734_3754	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
XHV734_3755	COG1234	tRNA 3'-trailer cleavage
XHV734_3757	COG0859	PFAM glycosyl transferase family 9
XHV734_3759	COG0631	protein serine/threonine phosphatase activity
XHV734_3760	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XHV734_3763	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XHV734_3765	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XHV734_3771	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
XHV734_3773	COG0544	peptidyl-prolyl cis-trans isomerase activity
XHV734_3784	COG4695	Portal protein
XHV734_3836	COG0473	3-isopropylmalate dehydrogenase activity
XHV734_3839	COG4783	chaperone-mediated protein folding
XHV734_3840	COG0745	RESPONSE REGULATOR receiver
XHV734_3842	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
XHV734_3844	COG0438	transferase activity, transferring glycosyl groups
XHV734_3845	COG0671	phosphoesterase, PA-phosphatase related
XHV734_3847	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XHV734_3849	COG3291	Pkd domain containing protein
XHV734_3850	COG2833	Protein of unknown function (DUF455)
XHV734_3855	COG0285	dihydrofolate synthase activity
XHV734_3858	COG0406	alpha-ribazole phosphatase activity
XHV734_3864	COG1063	alcohol dehydrogenase
XHV734_3868	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
XHV734_3869	COG4208	sulfate ABC transporter
XHV734_3870	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
XHV734_3871	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
XHV734_3872	COG0156	8-amino-7-oxononanoate synthase activity
XHV734_3876	COG2885	chlorophyll binding
XHV734_3877	COG0604	alcohol dehydrogenase
XHV734_3878	COG1902	pentaerythritol trinitrate reductase activity
XHV734_3878	COG0446	pyridine nucleotide-disulphide oxidoreductase
XHV734_3884	COG0625	glutathione transferase activity
XHV734_3886	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XHV734_3889	COG1217	gtp-binding protein TYPA
XHV734_3891	COG0154	amidase activity
XHV734_3893	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
XHV734_3896	COG0203	ribosomal protein L17
XHV734_3901	COG0201	protein transport
XHV734_3910	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
XHV734_3912	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
XHV734_3913	COG0255	Belongs to the universal ribosomal protein uL29 family
XHV734_3916	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
XHV734_3918	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XHV734_3922	COG0051	transcription antitermination factor activity, RNA binding
XHV734_3923	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XHV734_3926	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
XHV734_3927	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
XHV734_3930	COG0222	ribosome binding
XHV734_3931	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
XHV734_3932	COG0081	regulation of translation
XHV734_3933	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
XHV734_3934	COG0250	Participates in transcription elongation, termination and antitermination
XHV734_3937	COG0012	GTP binding
XHV734_3938	COG0193	aminoacyl-tRNA hydrolase activity
XHV734_3939	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
XHV734_3940	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
XHV734_3942	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
XHV734_3944	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
XHV734_3948	COG0521	Mo-molybdopterin cofactor biosynthetic process
XHV734_3952	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XHV734_3953	COG1295	ribonuclease BN
XHV734_3958	COG1404	Belongs to the peptidase S8 family
XHV734_3959	COG1404	Belongs to the peptidase S8 family
XHV734_3960	COG1404	Belongs to the peptidase S8 family
XHV734_3961	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XHV734_3973	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XHV734_3973	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XHV734_3977	COG2890	protein-(glutamine-N5) methyltransferase activity
XHV734_3979	COG3634	alkyl hydroperoxide reductase activity
XHV734_3980	COG0583	DNA-binding transcription factor activity
XHV734_3981	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XHV734_3982	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
XHV734_3985	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XHV734_3987	COG2197	response regulator
XHV734_3988	COG0784	Response regulator, receiver
XHV734_3988	COG2205	protein histidine kinase activity
XHV734_3988	COG5002	protein histidine kinase activity
XHV734_3992	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XHV734_3993	COG0697	spore germination
XHV734_4008	COG1024	Enoyl-CoA hydratase
XHV734_4010	COG0318	PFAM AMP-dependent synthetase and ligase
XHV734_4011	COG0583	DNA-binding transcription factor activity
XHV734_4012	COG3384	dioxygenase
XHV734_4018	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XHV734_4019	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XHV734_4021	COG2096	Adenosyltransferase
XHV734_4022	COG0123	including yeast histone deacetylase and acetoin utilization protein
XHV734_4024	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
XHV734_4027	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
XHV734_4028	COG2967	ApaG domain
XHV734_4029	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
XHV734_4030	COG0431	NADPH-dependent FMN reductase
XHV734_4031	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XHV734_4033	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XHV734_4034	COG1116	anion transmembrane transporter activity
XHV734_4038	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
XHV734_4043	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
XHV734_4045	COG0642	Histidine kinase
XHV734_4048	COG4181	ATPase activity
XHV734_4050	COG2175	clavaminate synthase activity
XHV734_4052	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
XHV734_4056	COG2963	transposase activity
XHV734_4057	COG2801	Transposase and inactivated derivatives
XHV734_4068	COG4771	TonB-dependent receptor
XHV734_4071	COG0667	Aldo Keto reductase
XHV734_4072	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
XHV734_4077	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XHV734_4078	COG4106	trans-aconitate 2-methyltransferase activity
XHV734_4080	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
XHV734_4084	COG2885	chlorophyll binding
XHV734_4088	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
XHV734_4100	COG3321	synthase
XHV734_4100	COG1028	Short-chain dehydrogenase reductase Sdr
XHV734_4100	COG0604	alcohol dehydrogenase
XHV734_4102	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XHV734_4107	COG0494	nUDIX hydrolase
XHV734_4110	COG0739	heme binding
XHV734_4115	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
XHV734_4116	COG1181	Belongs to the D-alanine--D-alanine ligase family
XHV734_4117	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XHV734_4121	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
XHV734_4122	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
XHV734_4124	COG3116	cell division
XHV734_4133	COG0792	nuclease activity
XHV734_4134	COG1988	membrane-bound metal-dependent
XHV734_4135	COG0277	FAD linked oxidase domain protein
XHV734_4136	COG0745	RESPONSE REGULATOR receiver
XHV734_4137	COG2205	protein histidine kinase activity
XHV734_4139	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
XHV734_4140	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
XHV734_4144	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
XHV734_4152	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XHV734_4152	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XHV734_4155	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
XHV734_4157	COG0488	(ABC) transporter
XHV734_4158	COG0242	peptide deformylase activity
XHV734_4161	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
XHV734_4170	COG2188	Transcriptional regulator
XHV734_4176	COG2963	transposase activity
XHV734_4177	COG2801	Transposase and inactivated derivatives
XHV734_4178	COG2188	Transcriptional regulator
XHV734_4180	COG1450	Type ii and iii secretion system protein
XHV734_4183	COG3166	PFAM Fimbrial assembly family protein
XHV734_4184	COG3156	type II secretion system protein K
XHV734_4185	COG4795	General secretion pathway protein
XHV734_4186	COG2165	general secretion pathway protein
XHV734_4187	COG4970	Tfp pilus assembly protein FimT
XHV734_4188	COG2165	general secretion pathway protein
XHV734_4189	COG1459	type II secretion system
XHV734_4190	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XHV734_4191	COG1404	Belongs to the peptidase S8 family
XHV734_4192	COG5295	Hep Hag repeat protein
XHV734_4194	COG1404	Belongs to the peptidase S8 family
XHV734_4196	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XHV734_4196	COG0047	phosphoribosylformylglycinamidine synthase activity
XHV734_4197	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XHV734_4198	COG4974	Belongs to the 'phage' integrase family
XHV734_4201	COG0795	lipopolysaccharide-transporting ATPase activity
XHV734_4205	COG0525	valine-tRNA ligase activity
XHV734_4211	COG1183	phosphatidylcholine synthase activity
XHV734_4213	COG0442	prolyl-tRNA aminoacylation
XHV734_4216	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XHV734_4217	COG1127	ABC transporter
XHV734_4218	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XHV734_4218	COG3218	ABC-type transport auxiliary lipoprotein component
XHV734_4228	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XHV734_4229	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
XHV734_4229	COG0662	Cupin 2, conserved barrel domain protein
XHV734_4234	COG2086	electron transfer activity
XHV734_4237	COG0463	Glycosyl transferase, family 2
XHV734_4242	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
XHV734_4250	COG0626	cystathionine gamma-synthase activity
XHV734_4257	COG0625	glutathione transferase activity
XHV734_4260	COG0513	Belongs to the DEAD box helicase family
XHV734_4262	COG4771	TonB-dependent receptor
XHV734_4263	COG0720	synthase
XHV734_4265	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
XHV734_4266	COG1956	GAF domain-containing protein
XHV734_4268	COG2819	hydrolase of the alpha beta superfamily
XHV734_4270	COG0546	phosphoglycolate phosphatase activity
XHV734_4271	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
XHV734_4272	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XHV734_4275	COG0339	signal peptide processing
XHV734_4284	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XHV734_4285	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XHV734_4287	COG1136	(ABC) transporter
XHV734_4289	COG0577	efflux transmembrane transporter activity
XHV734_4291	COG4191	Histidine kinase
XHV734_4296	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
XHV734_4299	COG0355	proton-transporting ATP synthase activity, rotational mechanism
XHV734_4304	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
XHV734_4307	COG0356	it plays a direct role in the translocation of protons across the membrane
XHV734_4311	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XHV734_4313	COG0508	dehydrogenase complex catalyzes the overall conversion of
XHV734_4319	COG2011	ABC-type metal ion transport system permease component
XHV734_4320	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
XHV734_4321	COG0697	spore germination
XHV734_4323	COG1666	GTP binding
XHV734_4327	COG1187	pseudouridine synthase activity
XHV734_4328	COG2813	Specifically methylates the guanine in position
XHV734_4332	COG2198	Histidine kinase
XHV734_4332	COG0784	Response regulator, receiver
XHV734_4332	COG2205	protein histidine kinase activity
XHV734_4332	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XHV734_4336	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
XHV734_4337	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XHV734_4360	COG2826	transposase and inactivated derivatives, IS30 family
XHV734_4365	COG0842	Transport permease protein
XHV734_4366	COG1131	(ABC) transporter
XHV734_4367	COG0025	NhaP-type Na H and K H
XHV734_4370	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
XHV734_4371	COG1573	uracil-dna glycosylase
XHV734_4375	COG3384	dioxygenase
XHV734_4377	COG0583	DNA-binding transcription factor activity
XHV734_4379	COG0667	Aldo Keto reductase
XHV734_4382	COG3590	peptidase
XHV734_4387	COG0531	amino acid
XHV734_4390	COG2972	Histidine kinase
XHV734_4393	COG3685	Protein conserved in bacteria
XHV734_4394	COG3546	catalase activity
XHV734_4400	COG2204	response regulator
XHV734_4405	COG1028	Short-chain dehydrogenase reductase Sdr
XHV734_4406	COG3039	Transposase
XHV734_4407	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
XHV734_4411	COG1132	(ABC) transporter
XHV734_4415	COG1063	alcohol dehydrogenase
XHV734_4420	COG0583	DNA-binding transcription factor activity
XHV734_4421	COG2814	Major facilitator Superfamily
XHV734_4429	COG1131	(ABC) transporter
XHV734_4433	COG0251	oxidation-reduction process
XHV734_4440	COG0659	secondary active sulfate transmembrane transporter activity
XHV734_4444	COG4977	sequence-specific DNA binding
XHV734_4448	COG1309	transcriptional regulator
XHV734_4450	COG0583	DNA-binding transcription factor activity
XHV734_4451	COG1902	pentaerythritol trinitrate reductase activity
XHV734_4468	COG2801	Transposase and inactivated derivatives
XHV734_4469	COG2963	transposase activity
XHV734_4471	COG2963	transposase activity
XHV734_4472	COG2801	Transposase and inactivated derivatives
XHV734_4473	COG3002	Belongs to the UPF0753 family
XHV734_4488	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XHV734_4489	COG1490	D-aminoacyl-tRNA deacylase activity
XHV734_4490	COG1560	Kdo2-lipid A biosynthetic process
XHV734_4499	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
XHV734_4499	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XHV734_4500	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
XHV734_4501	COG0242	peptide deformylase activity
XHV734_4502	COG1652	LysM domain
XHV734_4503	COG0758	DNA mediated transformation
XHV734_4507	COG1754	DNA topoisomerase type I activity
XHV734_4507	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XHV734_4508	COG0009	L-threonylcarbamoyladenylate synthase
XHV734_4512	COG1028	Short-chain dehydrogenase reductase Sdr
XHV734_4514	COG0616	signal peptide processing
XHV734_4515	COG0534	Mate efflux family protein
XHV734_4519	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
XHV734_4523	COG0625	glutathione transferase activity
XHV734_4526	COG1252	NADH dehydrogenase
XHV734_4527	COG2860	membrane
XHV734_4528	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XHV734_4529	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
XHV734_4530	COG2201	protein-glutamate methylesterase activity
XHV734_4531	COG2177	Part of the ABC transporter FtsEX involved in
XHV734_4532	COG2884	Cell division ATP-binding protein ftsE
XHV734_4534	COG3118	belongs to the thioredoxin family
XHV734_4535	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
XHV734_4538	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
XHV734_4545	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XHV734_4545	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XHV734_4546	COG1473	amidohydrolase
XHV734_4547	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XHV734_4548	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XHV734_4550	COG4948	Mandelate Racemase Muconate Lactonizing
XHV734_4552	COG3023	N-Acetylmuramoyl-L-alanine amidase
XHV734_4553	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
XHV734_4564	COG5383	Protein conserved in bacteria
XHV734_4567	COG0531	amino acid
XHV734_4570	COG4682	membrane
XHV734_4571	COG2133	pyrroloquinoline quinone binding
XHV734_4575	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
XHV734_4578	COG1610	YqeY-like protein
XHV734_4579	COG1295	ribonuclease BN
XHV734_4580	COG0358	DNA primase activity
XHV734_4584	COG0109	protoheme IX farnesyltransferase activity
XHV734_4590	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
XHV734_4593	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XHV734_4602	COG0739	heme binding
XHV734_4608	COG2807	transmembrane transport
XHV734_4609	COG0708	Exodeoxyribonuclease III
XHV734_4612	COG1192	Involved in chromosome partitioning
XHV734_4613	COG1475	DNA binding
XHV734_4616	COG0463	Glycosyl transferase, family 2
XHV734_4620	COG0756	dUTP diphosphatase activity
XHV734_4621	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
XHV734_4623	COG0018	arginyl-trna synthetase
XHV734_4625	COG4221	oxidoreductase activity
XHV734_4626	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
XHV734_4626	COG2755	lipolytic protein G-D-S-L family
XHV734_4628	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XHV734_4629	COG1166	arginine decarboxylase activity
XHV734_4637	COG2960	long-chain fatty acid transporting porin activity
XHV734_4638	COG0606	chelatase, subunit chli
XHV734_4643	COG4943	cyclic-guanylate-specific phosphodiesterase activity
XHV734_4656	COG1090	epimerase
XHV734_4659	COG0642	Histidine kinase
XHV734_4663	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XHV734_4668	COG1011	Hydrolase
XHV734_4669	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XHV734_4674	COG2197	response regulator
XHV734_4675	COG4585	Histidine kinase
XHV734_4676	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XHV734_4679	COG1136	(ABC) transporter
XHV734_4685	COG0697	spore germination
XHV734_4691	COG0180	Tryptophanyl-tRNA synthetase
XHV734_4692	COG3237	CsbD-like
XHV734_4699	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
XHV734_4703	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
XHV734_4704	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
XHV734_4704	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
XHV734_4706	COG3228	Belongs to the MtfA family
XHV734_4712	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XHV734_4718	COG1199	ATP-dependent helicase activity
XHV734_4725	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XHV734_4732	COG0625	glutathione transferase activity
XHV734_4740	COG4555	ABC transporter
XHV734_4742	COG1476	TRANSCRIPTIONal
XHV734_4748	COG1131	(ABC) transporter
XHV734_4749	COG0842	Transport permease protein
XHV734_4751	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XHV734_4755	COG1607	acyl-coa hydrolase
XHV734_4758	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XHV734_4759	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XHV734_4762	COG0045	succinate-CoA ligase (ADP-forming) activity
XHV734_4762	COG1042	CoA-binding domain protein
XHV734_4762	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XHV734_4765	COG1629	transport
XHV734_4765	COG4771	TonB-dependent receptor
XHV734_4766	COG2239	Acts as a magnesium transporter
XHV734_4769	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XHV734_4770	COG3387	PFAM Glycoside hydrolase 15-related
XHV734_4773	COG3100	YcgL domain-containing protein
XHV734_4774	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XHV734_4779	COG1028	Short-chain dehydrogenase reductase Sdr
XHV734_4785	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XHV734_4788	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XHV734_4805	COG3621	Patatin-like phospholipase
XHV734_4812	COG0210	DNA helicase
XHV734_4815	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XHV734_4817	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XHV734_4819	COG2159	amidohydrolase
XHV734_4825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XHV734_4829	COG3039	Transposase
XHV734_4834	COG3540	Alkaline phosphatase
XHV734_4836	COG2091	lysine biosynthetic process via aminoadipic acid
XHV734_4839	COG0708	Exodeoxyribonuclease III
XHV734_4842	COG1940	carbohydrate kinase activity
XHV734_4845	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XHV734_4850	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XHV734_4851	COG3162	membrane
XHV734_4864	COG1028	Short-chain dehydrogenase reductase Sdr
XHV734_4865	COG0179	Fumarylacetoacetate (FAA) hydrolase
XHV734_4867	COG4948	Mandelate Racemase Muconate Lactonizing
XHV734_4869	COG3254	rhamnose metabolic process
XHV734_4870	COG0738	Major facilitator superfamily
XHV734_4871	COG1414	Transcriptional regulator
XHV734_4874	COG1971	Probably functions as a manganese efflux pump
XHV734_4875	COG2205	protein histidine kinase activity
XHV734_4876	COG3459	Glycosyltransferase 36 associated
XHV734_4877	COG2211	Major facilitator Superfamily
XHV734_4878	COG3265	gluconokinase activity
XHV734_4879	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XHV734_4884	COG3039	Transposase
XHV734_4889	COG2911	Protein conserved in bacteria
XHV734_4890	COG0729	surface antigen
XHV734_4893	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XHV734_4895	COG0519	Catalyzes the synthesis of GMP from XMP
XHV734_4895	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XHV734_4897	COG0805	protein transport
XHV734_4898	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XHV734_4899	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XHV734_4901	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
XHV734_4905	COG2974	May be involved in recombination
XHV734_4906	COG0037	tRNA processing
XHV734_4908	COG2115	Belongs to the xylose isomerase family
XHV734_4911	COG3661	Belongs to the glycosyl hydrolase 67 family
XHV734_4913	COG4948	Mandelate Racemase Muconate Lactonizing
XHV734_4915	COG1472	Belongs to the glycosyl hydrolase 3 family
XHV734_4916	COG0246	Mannitol dehydrogenase
XHV734_4922	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XHV734_4923	COG1620	l-lactate permease
XHV734_4926	COG3386	PFAM SMP-30 Gluconolaconase
XHV734_4929	COG3250	beta-galactosidase activity
XHV734_4930	COG1904	glucuronate isomerase
XHV734_4931	COG3693	PFAM glycoside hydrolase, family 10
XHV734_4934	COG2211	Major facilitator Superfamily
XHV734_4943	COG2937	Belongs to the GPAT DAPAT family
XHV734_4949	COG0284	orotidine-5'-phosphate decarboxylase activity
XHV734_4950	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
XHV734_4951	COG3132	Protein of unknown function, DUF480
XHV734_4954	COG0210	DNA helicase
XHV734_4955	COG1435	thymidine kinase activity
XHV734_4957	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
XHV734_4959	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
XHV734_4965	COG3135	benzoate transporter
XHV734_4969	COG0676	glucose-6-phosphate 1-epimerase activity
XHV734_4972	COG0730	response to heat
XHV734_4979	COG0302	gtp cyclohydrolase
XHV734_4982	COG1566	PFAM secretion protein HlyD family protein
XHV734_4984	COG1289	transmembrane transporter activity
XHV734_4986	COG0477	Major facilitator Superfamily
XHV734_4987	COG0583	DNA-binding transcription factor activity
XHV734_4988	COG4221	oxidoreductase activity
XHV734_4991	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XHV734_4997	COG1192	Involved in chromosome partitioning
XHV734_4999	COG3550	peptidyl-serine autophosphorylation
XHV734_5011	COG3039	Transposase
XHV734_5027	COG2207	Transcriptional regulator
XHV734_5028	COG1028	Short-chain dehydrogenase reductase Sdr
XHV734_5030	COG3549	Plasmid maintenance system killer
XHV734_5033	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
XHV734_5034	COG1074	ATP-dependent DNA helicase activity
XHV734_5035	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
XHV734_5036	COG1127	ABC transporter
XHV734_5037	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XHV734_5038	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XHV734_5041	COG2853	Lipoprotein
XHV734_5047	COG0386	Belongs to the glutathione peroxidase family
XHV734_5050	COG1322	Protein conserved in bacteria
XHV734_5053	COG0625	glutathione transferase activity
XHV734_5054	COG0531	amino acid
XHV734_5055	COG3537	Alpha-1,2-mannosidase
XHV734_5058	COG2203	Gaf domain
XHV734_5058	COG2199	diguanylate cyclase activity
XHV734_5060	COG3835	regulator
XHV734_5062	COG1929	Belongs to the glycerate kinase type-1 family
XHV734_5063	COG2271	Major facilitator Superfamily
XHV734_5072	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XHV734_5073	COG1126	abc transporter atp-binding protein
XHV734_5075	COG1473	amidohydrolase
XHV734_5076	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XHV734_5077	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XHV734_5080	COG4206	TonB-dependent receptor
XHV734_5084	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XHV734_5085	COG0861	Integral membrane protein TerC family
XHV734_5088	COG0584	glycerophosphoryl diester phosphodiesterase
XHV734_5093	COG0706	membrane insertase activity
XHV734_p0009	COG2801	Transposase and inactivated derivatives
XHV734_p0010	COG2963	transposase activity
XHV734_p0013	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XHV734_p0020	COG2801	Transposase and inactivated derivatives
XHV734_p0021	COG2963	transposase activity
XHV734_p0043	COG3328	transposase activity
XHV734_p0064	COG5599	Phosphatase
XHV734_p0079	COG2826	transposase and inactivated derivatives, IS30 family