locus-tag	class	description
FZ025_00010	COG0668	transmembrane transport
FZ025_00020	COG0590	tRNA wobble adenosine to inosine editing
FZ025_00025	COG1321	iron dependent repressor
FZ025_00030	COG1914	H( )-stimulated, divalent metal cation uptake system
FZ025_00040	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
FZ025_00045	COG0166	Belongs to the GPI family
FZ025_00060	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FZ025_00070	COG0617	tRNA 3'-terminal CCA addition
FZ025_00080	COG0860	N-Acetylmuramoyl-L-alanine amidase
FZ025_00085	COG0477	Major facilitator Superfamily
FZ025_00090	COG2115	Belongs to the xylose isomerase family
FZ025_00095	COG1070	Carbohydrate kinase
FZ025_00105	COG1501	Belongs to the glycosyl hydrolase 31 family
FZ025_00125	COG0800	Aldolase
FZ025_00140	COG3734	2-keto-3-deoxy-galactonokinase
FZ025_00145	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FZ025_00150	COG1605	Chorismate mutase
FZ025_00150	COG0287	Prephenate dehydrogenase
FZ025_00155	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FZ025_00160	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FZ025_00165	COG2867	negative regulation of translational initiation
FZ025_00175	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FZ025_00180	COG0735	belongs to the Fur family
FZ025_00185	COG0497	DNA recombination
FZ025_00190	COG1420	regulation of RNA biosynthetic process
FZ025_00195	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FZ025_00200	COG0443	Heat shock 70 kDa protein
FZ025_00205	COG0484	heat shock protein binding
FZ025_00230	COG0531	amino acid
FZ025_00235	COG0531	amino acid
FZ025_00240	COG0235	Class ii aldolase
FZ025_00245	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FZ025_00250	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
FZ025_00265	COG0140	phosphoribosyl-ATP diphosphatase activity
FZ025_00265	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FZ025_00280	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FZ025_00295	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FZ025_00300	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FZ025_00310	COG0124	histidyl-tRNA synthetase
FZ025_00315	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FZ025_00325	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FZ025_00335	COG0083	homoserine kinase activity
FZ025_00340	COG0527	aspartate kinase activity
FZ025_00340	COG0460	homoserine dehydrogenase
FZ025_00355	COG1012	belongs to the aldehyde dehydrogenase family
FZ025_00370	COG0167	dihydroorotate dehydrogenase activity
FZ025_00375	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FZ025_00385	COG1794	racemase activity, acting on amino acids and derivatives
FZ025_00390	COG0671	phosphoesterase, PA-phosphatase related
FZ025_00405	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FZ025_00415	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FZ025_00500	COG3702	type iv secretory pathway
FZ025_00565	COG0556	nucleotide-excision repair
FZ025_00725	COG1611	Belongs to the LOG family
FZ025_00740	COG2095	MarC family integral membrane protein
FZ025_00750	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FZ025_00795	COG2969	positive regulation of protein catabolic process
FZ025_00800	COG0625	glutathione transferase activity
FZ025_00805	COG2857	Cytochrome c1
FZ025_00810	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FZ025_00815	COG0723	plastoquinol--plastocyanin reductase activity
FZ025_00820	COG0741	lytic transglycosylase activity
FZ025_00845	COG1702	phosphate starvation-inducible protein PhoH
FZ025_00850	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FZ025_00860	COG4535	Mg2 and Co2 transporter CorC
FZ025_00875	COG1012	belongs to the aldehyde dehydrogenase family
FZ025_00880	COG1177	transmembrane transport
FZ025_00885	COG1176	ABC-type spermidine putrescine transport system, permease component I
FZ025_00890	COG3842	ATPase activity
FZ025_00915	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FZ025_00920	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FZ025_00940	COG0174	glutamine synthetase
FZ025_00945	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FZ025_00950	COG0174	glutamine synthetase
FZ025_00955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FZ025_00960	COG0477	Major facilitator Superfamily
FZ025_01015	COG1012	belongs to the aldehyde dehydrogenase family
FZ025_01020	COG1917	Cupin 2, conserved barrel domain protein
FZ025_01020	COG1396	sequence-specific DNA binding
FZ025_01035	COG0686	Belongs to the AlaDH PNT family
FZ025_01055	COG2733	membrane
FZ025_01060	COG0784	Response regulator, receiver
FZ025_01060	COG2205	protein histidine kinase activity
FZ025_01060	COG5002	protein histidine kinase activity
FZ025_01105	COG0494	nUDIX hydrolase
FZ025_01115	COG1024	Enoyl-CoA hydratase
FZ025_01125	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FZ025_01130	COG0659	secondary active sulfate transmembrane transporter activity
FZ025_01150	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FZ025_01155	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FZ025_01160	COG0573	inorganic phosphate transmembrane transporter activity
FZ025_01165	COG0581	inorganic phosphate transmembrane transporter activity
FZ025_01175	COG0704	Plays a role in the regulation of phosphate uptake
FZ025_01200	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FZ025_01225	COG3039	Transposase
FZ025_01230	COG2826	transposase and inactivated derivatives, IS30 family
FZ025_01250	COG3668	Plasmid stabilization system
FZ025_01255	COG0745	RESPONSE REGULATOR receiver
FZ025_01255	COG3706	GGDEF domain
FZ025_01260	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FZ025_01270	COG0557	exoribonuclease II activity
FZ025_01335	COG2977	Belongs to the P-Pant transferase superfamily
FZ025_01350	COG2822	iron ion transport
FZ025_01360	COG0477	Major facilitator Superfamily
FZ025_01370	COG4372	Transposase
FZ025_01385	COG0583	DNA-binding transcription factor activity
FZ025_01415	COG0077	Prephenate dehydratase
FZ025_01415	COG1605	Chorismate mutase
FZ025_01420	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FZ025_01425	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FZ025_01430	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FZ025_01465	COG4221	oxidoreductase activity
FZ025_01495	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FZ025_01570	COG0069	glutamate synthase activity
FZ025_01575	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FZ025_01585	COG1609	Transcriptional regulator
FZ025_01590	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FZ025_01590	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FZ025_01595	COG1105	Belongs to the carbohydrate kinase PfkB family
FZ025_01600	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FZ025_01600	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FZ025_01615	COG0745	RESPONSE REGULATOR receiver
FZ025_01635	COG0577	efflux transmembrane transporter activity
FZ025_01635	COG1136	(ABC) transporter
FZ025_01675	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FZ025_01690	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
FZ025_01695	COG0583	DNA-binding transcription factor activity
FZ025_01700	COG0604	alcohol dehydrogenase
FZ025_01705	COG0596	Alpha beta hydrolase
FZ025_01725	COG1335	isochorismatase
FZ025_01755	COG1733	regulation of RNA biosynthetic process
FZ025_01760	COG1028	Short-chain dehydrogenase reductase Sdr
FZ025_01775	COG1028	Short-chain dehydrogenase reductase Sdr
FZ025_01795	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FZ025_01805	COG0348	domain, Protein
FZ025_01855	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FZ025_01870	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FZ025_01875	COG3291	Pkd domain containing protein
FZ025_01880	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FZ025_01885	COG0405	Gamma-glutamyltransferase
FZ025_01890	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FZ025_01920	COG0717	Belongs to the dCTP deaminase family
FZ025_01925	COG0489	protein tyrosine kinase activity
FZ025_01935	COG4771	TonB-dependent receptor
FZ025_01950	COG0514	ATP-dependent DNA helicase (RecQ)
FZ025_01980	COG0602	queuosine metabolic process
FZ025_01990	COG2885	chlorophyll binding
FZ025_01995	COG0823	Involved in the tonB-independent uptake of proteins
FZ025_02005	COG0848	biopolymer transport protein
FZ025_02015	COG0824	Thioesterase
FZ025_02020	COG2255	four-way junction helicase activity
FZ025_02030	COG0632	four-way junction helicase activity
FZ025_02040	COG0217	transcriptional regulatory protein
FZ025_02060	COG2207	Transcriptional regulator
FZ025_02070	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FZ025_02105	COG0488	(ABC) transporter
FZ025_02160	COG4651	solute:proton antiporter activity
FZ025_02160	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FZ025_02170	COG4772	TonB-dependent receptor
FZ025_02180	COG4264	IucA IucC family
FZ025_02185	COG2814	Major facilitator Superfamily
FZ025_02190	COG4264	IucA IucC family
FZ025_02195	COG0019	diaminopimelate decarboxylase activity
FZ025_02200	COG2223	nitrite transmembrane transporter activity
FZ025_02235	COG0542	response to heat
FZ025_02255	COG0454	-acetyltransferase
FZ025_02295	COG0742	ribosomal rna small subunit methyltransferase
FZ025_02300	COG0326	Molecular chaperone. Has ATPase activity
FZ025_02310	COG3345	alpha-galactosidase
FZ025_02320	COG4771	TonB-dependent receptor
FZ025_02330	COG3507	Belongs to the glycosyl hydrolase 43 family
FZ025_02340	COG4206	TonB-dependent receptor
FZ025_02365	COG0531	amino acid
FZ025_02380	COG0006	proline dipeptidase activity
FZ025_02390	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FZ025_02405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FZ025_02410	COG3938	Belongs to the proline racemase family
FZ025_02420	COG0552	protein localization to endoplasmic reticulum
FZ025_02425	COG1194	a g-specific adenine glycosylase
FZ025_02505	COG3300	MHYT domain
FZ025_02505	COG5001	Diguanylate cyclase
FZ025_02510	COG1185	polyribonucleotide nucleotidyltransferase activity
FZ025_02520	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FZ025_02535	COG0195	Participates in both transcription termination and antitermination
FZ025_02550	COG1007	ATP synthesis coupled electron transport
FZ025_02590	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FZ025_02595	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FZ025_02605	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FZ025_02615	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FZ025_02630	COG0149	triose-phosphate isomerase activity
FZ025_02635	COG1028	Short-chain dehydrogenase reductase Sdr
FZ025_02650	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FZ025_02680	COG0101	tRNA pseudouridine synthase activity
FZ025_02715	COG2890	protein-(glutamine-N5) methyltransferase activity
FZ025_02725	COG0688	phosphatidylethanolamine metabolic process
FZ025_02735	COG0741	lytic transglycosylase activity
FZ025_02740	COG0433	COG0433 Predicted ATPase
FZ025_02750	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FZ025_02765	COG0629	single-stranded DNA binding
FZ025_02770	COG0142	geranyltranstransferase activity
FZ025_02790	COG0527	aspartate kinase activity
FZ025_02795	COG0384	phenazine biosynthesis protein PhzF
FZ025_02805	COG1764	response to oxidative stress
FZ025_02850	COG0719	Fe-S assembly protein
FZ025_02855	COG0396	ATPase activity
FZ025_02860	COG0719	Fe-S assembly protein
FZ025_02865	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FZ025_02875	COG2146	nitrite reductase [NAD(P)H] activity
FZ025_02880	COG4774	siderophore transport
FZ025_02905	COG1477	protein flavinylation
FZ025_02910	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FZ025_02945	COG1555	photosystem II stabilization
FZ025_02960	COG3178	'Phosphotransferase
FZ025_02965	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FZ025_02970	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FZ025_02975	COG0628	permease
FZ025_03000	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FZ025_03035	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FZ025_03050	COG1137	ATPase activity
FZ025_03065	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FZ025_03075	COG1660	Displays ATPase and GTPase activities
FZ025_03085	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FZ025_03090	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FZ025_03095	COG2239	Acts as a magnesium transporter
FZ025_03110	COG1113	amino acid transport
FZ025_03115	COG0840	transmembrane signaling receptor activity
FZ025_03155	COG2826	transposase and inactivated derivatives, IS30 family
FZ025_03170	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FZ025_03185	COG0519	Catalyzes the synthesis of GMP from XMP
FZ025_03215	COG1192	Involved in chromosome partitioning
FZ025_03230	COG4959	Type IV secretory pathway protease TraF
FZ025_03255	COG1566	PFAM secretion protein HlyD family protein
FZ025_03260	COG2814	Major facilitator Superfamily
FZ025_03350	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FZ025_03375	COG0754	glutathionylspermidine amidase activity
FZ025_03380	COG5463	Belongs to the UPF0441 family
FZ025_03400	COG1842	Phage shock protein A
FZ025_03440	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FZ025_03445	COG2814	Major facilitator Superfamily
FZ025_03465	COG3038	cytochrome b561
FZ025_03485	COG1760	l-serine dehydratase
FZ025_03490	COG3706	GGDEF domain
FZ025_03500	COG0460	homoserine dehydrogenase
FZ025_03500	COG0527	aspartate kinase activity
FZ025_03505	COG0626	cystathionine gamma-synthase activity
FZ025_03510	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FZ025_03515	COG0739	heme binding
FZ025_03520	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FZ025_03525	COG1272	protein, Hemolysin III
FZ025_03530	COG2982	Protein involved in outer membrane biogenesis
FZ025_03535	COG0517	IMP dehydrogenase activity
FZ025_03540	COG0463	Glycosyl transferase, family 2
FZ025_03545	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FZ025_03550	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FZ025_03580	COG1960	acyl-CoA dehydrogenase activity
FZ025_03615	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FZ025_03620	COG1216	Glycosyl transferase, family 2
FZ025_03630	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FZ025_03670	COG3279	Response regulator of the LytR AlgR family
FZ025_03675	COG3275	phosphorelay sensor kinase activity
FZ025_03690	COG1643	Atp-dependent helicase
FZ025_03695	COG0783	Belongs to the Dps family
FZ025_03705	COG0039	L-malate dehydrogenase activity
FZ025_03715	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FZ025_03740	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FZ025_03750	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FZ025_03755	COG0203	ribosomal protein L17
FZ025_03760	COG0202	RNA polymerase activity
FZ025_03765	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FZ025_03770	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FZ025_03775	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FZ025_03780	COG0201	protein transport
FZ025_03790	COG1841	ribosomal large subunit assembly
FZ025_03795	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FZ025_03815	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FZ025_03820	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FZ025_03825	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FZ025_03830	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FZ025_03835	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FZ025_03840	COG0255	Belongs to the universal ribosomal protein uL29 family
FZ025_03855	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FZ025_03865	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FZ025_03870	COG0089	rRNA binding
FZ025_03885	COG0051	transcription antitermination factor activity, RNA binding
FZ025_03890	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FZ025_03895	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FZ025_03910	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FZ025_03920	COG0222	ribosome binding
FZ025_03935	COG0081	regulation of translation
FZ025_03940	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FZ025_03945	COG0250	Participates in transcription elongation, termination and antitermination
FZ025_03950	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FZ025_03960	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FZ025_03980	COG0012	GTP binding
FZ025_03985	COG0193	aminoacyl-tRNA hydrolase activity
FZ025_03995	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FZ025_04020	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FZ025_04025	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FZ025_04040	COG0521	Mo-molybdopterin cofactor biosynthetic process
FZ025_04055	COG1254	Belongs to the acylphosphatase family
FZ025_04060	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FZ025_04065	COG1295	ribonuclease BN
FZ025_04085	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FZ025_04090	COG0473	3-isopropylmalate dehydrogenase activity
FZ025_04105	COG4783	chaperone-mediated protein folding
FZ025_04120	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FZ025_04125	COG0248	Ppx GppA phosphatase
FZ025_04130	COG0438	transferase activity, transferring glycosyl groups
FZ025_04150	COG2833	Protein of unknown function (DUF455)
FZ025_04170	COG0285	dihydrofolate synthase activity
FZ025_04175	COG0588	phosphoglycerate mutase activity
FZ025_04195	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FZ025_04200	COG4208	sulfate ABC transporter
FZ025_04205	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FZ025_04210	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FZ025_04215	COG0156	8-amino-7-oxononanoate synthase activity
FZ025_04225	COG1187	pseudouridine synthase activity
FZ025_04235	COG2885	chlorophyll binding
FZ025_04240	COG0583	DNA-binding transcription factor activity
FZ025_04245	COG2814	Major facilitator Superfamily
FZ025_04255	COG0667	Aldo Keto reductase
FZ025_04265	COG0446	pyridine nucleotide-disulphide oxidoreductase
FZ025_04265	COG1902	pentaerythritol trinitrate reductase activity
FZ025_04285	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FZ025_04315	COG1073	alpha beta
FZ025_04335	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FZ025_04355	COG4585	Histidine kinase
FZ025_04365	COG0850	regulation of cytokinetic process
FZ025_04370	COG2894	cell division
FZ025_04375	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FZ025_04385	COG2205	protein histidine kinase activity
FZ025_04390	COG0745	RESPONSE REGULATOR receiver
FZ025_04400	COG2194	sulfuric ester hydrolase activity
FZ025_04420	COG2814	Major facilitator Superfamily
FZ025_04425	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FZ025_04425	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FZ025_04435	COG0753	catalase activity
FZ025_04440	COG1063	alcohol dehydrogenase
FZ025_04450	COG3459	Glycosyltransferase 36 associated
FZ025_04455	COG2186	Transcriptional regulator
FZ025_04475	COG2271	Major facilitator Superfamily
FZ025_04480	COG1028	Short-chain dehydrogenase reductase Sdr
FZ025_04540	COG1877	trehalose-phosphatase activity
FZ025_04545	COG3387	PFAM Glycoside hydrolase 15-related
FZ025_04560	COG0840	transmembrane signaling receptor activity
FZ025_04580	COG0564	pseudouridine synthase activity
FZ025_04585	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FZ025_04590	COG1125	glycine betaine transport
FZ025_04595	COG1174	glycine betaine transport
FZ025_04610	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FZ025_04620	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FZ025_04620	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FZ025_04625	COG4993	Dehydrogenase
FZ025_04650	COG3657	addiction module killer protein
FZ025_04655	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FZ025_04690	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FZ025_04705	COG0745	RESPONSE REGULATOR receiver
FZ025_04715	COG0189	ligase activity
FZ025_04725	COG3511	phospholipase C
FZ025_04730	COG4251	negative regulation of phosphorylation
FZ025_04730	COG2203	Gaf domain
FZ025_04730	COG3706	GGDEF domain
FZ025_04730	COG5001	Diguanylate cyclase
FZ025_04735	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FZ025_04740	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FZ025_04750	COG3485	protocatechuate 3,4-dioxygenase
FZ025_04755	COG3485	protocatechuate 3,4-dioxygenase
FZ025_04765	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FZ025_04835	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FZ025_04855	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FZ025_04855	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FZ025_04895	COG3634	alkyl hydroperoxide reductase activity
FZ025_04900	COG0583	DNA-binding transcription factor activity
FZ025_04910	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FZ025_04940	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FZ025_04955	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FZ025_04965	COG0697	spore germination
FZ025_05005	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FZ025_05010	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FZ025_05020	COG2096	Adenosyltransferase
FZ025_05035	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FZ025_05040	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FZ025_05045	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FZ025_05050	COG2967	ApaG domain
FZ025_05055	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FZ025_05085	COG1704	LemA family
FZ025_05090	COG0861	Integral membrane protein TerC family
FZ025_05095	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FZ025_05105	COG0642	Histidine kinase
FZ025_05120	COG4181	ATPase activity
FZ025_05125	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FZ025_05130	COG2175	clavaminate synthase activity
FZ025_05140	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FZ025_05145	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FZ025_05165	COG4771	TonB-dependent receptor
FZ025_05175	COG0667	Aldo Keto reductase
FZ025_05180	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FZ025_05190	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FZ025_05200	COG0242	peptide deformylase activity
FZ025_05205	COG0457	Tetratricopeptide repeat
FZ025_05210	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FZ025_05215	COG1215	transferase activity, transferring glycosyl groups
FZ025_05220	COG1215	transferase activity, transferring glycosyl groups
FZ025_05235	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FZ025_05290	COG2188	Transcriptional regulator
FZ025_05300	COG1450	Type ii and iii secretion system protein
FZ025_05315	COG3166	PFAM Fimbrial assembly family protein
FZ025_05320	COG3156	type II secretion system protein K
FZ025_05325	COG4795	General secretion pathway protein
FZ025_05330	COG2165	general secretion pathway protein
FZ025_05335	COG4970	Tfp pilus assembly protein FimT
FZ025_05340	COG2165	general secretion pathway protein
FZ025_05345	COG1459	type II secretion system
FZ025_05350	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FZ025_05360	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FZ025_05360	COG0047	phosphoribosylformylglycinamidine synthase activity
FZ025_05365	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FZ025_05370	COG4974	Belongs to the 'phage' integrase family
FZ025_05390	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FZ025_05395	COG2927	DNA polymerase III (CHI subunit)
FZ025_05410	COG0525	valine-tRNA ligase activity
FZ025_05430	COG1183	phosphatidylcholine synthase activity
FZ025_05440	COG0442	prolyl-tRNA aminoacylation
FZ025_05455	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FZ025_05460	COG1127	ABC transporter
FZ025_05465	COG3218	ABC-type transport auxiliary lipoprotein component
FZ025_05465	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FZ025_05505	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FZ025_05510	COG0662	Cupin 2, conserved barrel domain protein
FZ025_05510	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FZ025_05535	COG2086	electron transfer activity
FZ025_05550	COG0463	Glycosyl transferase, family 2
FZ025_05560	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FZ025_05570	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FZ025_05575	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
FZ025_05585	COG0438	transferase activity, transferring glycosyl groups
FZ025_05610	COG0626	cystathionine gamma-synthase activity
FZ025_05640	COG0625	glutathione transferase activity
FZ025_05650	COG0513	Belongs to the DEAD box helicase family
FZ025_05660	COG4771	TonB-dependent receptor
FZ025_05665	COG0720	synthase
FZ025_05675	COG3039	Transposase
FZ025_05690	COG0583	DNA-binding transcription factor activity
FZ025_05700	COG2814	Major facilitator Superfamily
FZ025_05710	COG0583	DNA-binding transcription factor activity
FZ025_05715	COG2814	Major facilitator Superfamily
FZ025_05720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FZ025_05730	COG1028	Short-chain dehydrogenase reductase Sdr
FZ025_05735	COG1028	Short-chain dehydrogenase reductase Sdr
FZ025_05780	COG0583	DNA-binding transcription factor activity
FZ025_05785	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FZ025_05790	COG1956	GAF domain-containing protein
FZ025_05800	COG4206	TonB-dependent receptor
FZ025_05805	COG0583	DNA-binding transcription factor activity
FZ025_05820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FZ025_05825	COG0546	phosphoglycolate phosphatase activity
FZ025_05850	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FZ025_05865	COG0339	signal peptide processing
FZ025_05870	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FZ025_05880	COG2217	Heavy metal translocating P-type atpase
FZ025_05895	COG2132	Multicopper oxidase
FZ025_05930	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FZ025_05940	COG0577	efflux transmembrane transporter activity
FZ025_05940	COG1136	(ABC) transporter
FZ025_05945	COG0577	efflux transmembrane transporter activity
FZ025_05945	COG1136	(ABC) transporter
FZ025_05950	COG1136	(ABC) transporter
FZ025_05950	COG0577	efflux transmembrane transporter activity
FZ025_05955	COG1136	(ABC) transporter
FZ025_05955	COG0577	efflux transmembrane transporter activity
FZ025_05960	COG0577	efflux transmembrane transporter activity
FZ025_05970	COG2204	response regulator
FZ025_05975	COG4191	Histidine kinase
FZ025_05985	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FZ025_06000	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FZ025_06010	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FZ025_06025	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FZ025_06035	COG0356	it plays a direct role in the translocation of protons across the membrane
FZ025_06050	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FZ025_06055	COG0508	dehydrogenase complex catalyzes the overall conversion of
FZ025_06095	COG0697	spore germination
FZ025_06100	COG1666	GTP binding
FZ025_06110	COG1187	pseudouridine synthase activity
FZ025_06115	COG2813	Specifically methylates the guanine in position
FZ025_06135	COG2205	protein histidine kinase activity
FZ025_06135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FZ025_06155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FZ025_06230	COG0842	Transport permease protein
FZ025_06235	COG1131	(ABC) transporter
FZ025_06240	COG0025	NhaP-type Na H and K H
FZ025_06250	COG1573	uracil-dna glycosylase
FZ025_06265	COG3384	dioxygenase
FZ025_06290	COG0667	Aldo Keto reductase
FZ025_06295	COG0667	Aldo Keto reductase
FZ025_06305	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FZ025_06310	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FZ025_06335	COG5001	Diguanylate cyclase
FZ025_06380	COG3039	Transposase
FZ025_06405	COG2826	transposase and inactivated derivatives, IS30 family
FZ025_06420	COG0366	Alpha amylase catalytic
FZ025_06425	COG0366	Alpha amylase catalytic
FZ025_06430	COG3537	Alpha-1,2-mannosidase
FZ025_06435	COG1609	Transcriptional regulator
FZ025_06450	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FZ025_06455	COG1490	D-aminoacyl-tRNA deacylase activity
FZ025_06465	COG1247	-acetyltransferase
FZ025_06470	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FZ025_06485	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FZ025_06495	COG0318	PFAM AMP-dependent synthetase and ligase
FZ025_06500	COG3268	Saccharopine dehydrogenase
FZ025_06520	COG1215	transferase activity, transferring glycosyl groups
FZ025_06535	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FZ025_06540	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FZ025_06540	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FZ025_06545	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FZ025_06550	COG0242	peptide deformylase activity
FZ025_06555	COG1652	LysM domain
FZ025_06560	COG0758	DNA mediated transformation
FZ025_06575	COG1714	RDD family
FZ025_06580	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FZ025_06580	COG1754	DNA topoisomerase type I activity
FZ025_06585	COG0009	L-threonylcarbamoyladenylate synthase
FZ025_06600	COG1028	Short-chain dehydrogenase reductase Sdr
FZ025_06610	COG0616	signal peptide processing
FZ025_06615	COG0534	Mate efflux family protein
FZ025_06630	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FZ025_06640	COG1252	NADH dehydrogenase
FZ025_06645	COG2860	membrane
FZ025_06650	COG1396	sequence-specific DNA binding
FZ025_06665	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FZ025_06670	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FZ025_06675	COG3437	response regulator, receiver
FZ025_06680	COG2177	Part of the ABC transporter FtsEX involved in
FZ025_06685	COG2884	Cell division ATP-binding protein ftsE
FZ025_06695	COG3118	belongs to the thioredoxin family
FZ025_06700	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FZ025_06710	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
FZ025_06755	COG1518	maintenance of DNA repeat elements
FZ025_06760	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FZ025_06770	COG1652	LysM domain
FZ025_06785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FZ025_06790	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FZ025_06805	COG5383	Protein conserved in bacteria
FZ025_06855	COG4152	abc transporter atp-binding protein
FZ025_06885	COG3409	Peptidoglycan-binding domain 1 protein
FZ025_06920	COG4771	TonB-dependent receptor
FZ025_06930	COG4948	Mandelate Racemase Muconate Lactonizing
FZ025_06945	COG0531	amino acid
FZ025_06955	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FZ025_06970	COG2133	pyrroloquinoline quinone binding
FZ025_06985	COG2308	Evidence 4 Homologs of previously reported genes of
FZ025_06990	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FZ025_07000	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FZ025_07010	COG1295	ribonuclease BN
FZ025_07015	COG0358	DNA primase activity
FZ025_07030	COG0109	protoheme IX farnesyltransferase activity
FZ025_07035	COG1612	heme a metabolic process
FZ025_07060	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FZ025_07100	COG0793	Belongs to the peptidase S41A family
FZ025_07105	COG4942	peptidase
FZ025_07115	COG2234	aminopeptidase activity
FZ025_07120	COG1064	alcohol dehydrogenase
FZ025_07150	COG3135	benzoate transporter
FZ025_07170	COG0676	glucose-6-phosphate 1-epimerase activity
FZ025_07175	COG3706	GGDEF domain
FZ025_07180	COG3012	SEC-C Motif Domain Protein
FZ025_07185	COG0730	response to heat
FZ025_07215	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FZ025_07220	COG0302	gtp cyclohydrolase
FZ025_07225	COG0477	Major facilitator Superfamily
FZ025_07250	COG1396	sequence-specific DNA binding
FZ025_07250	COG3800	Transcriptional regulator
FZ025_07275	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FZ025_07280	COG1074	ATP-dependent DNA helicase activity
FZ025_07285	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FZ025_07295	COG0459	protein refolding
FZ025_07300	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FZ025_07305	COG2356	endonuclease I
FZ025_07310	COG1324	tolerance protein
FZ025_07320	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FZ025_07335	COG1733	regulation of RNA biosynthetic process
FZ025_07340	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FZ025_07345	COG0511	ligase activity, forming carbon-carbon bonds
FZ025_07355	COG0439	Biotin carboxylase
FZ025_07370	COG2264	protein methyltransferase activity
FZ025_07385	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FZ025_07405	COG0151	Belongs to the GarS family
FZ025_07475	COG2814	Major facilitator Superfamily
FZ025_07480	COG1289	transmembrane transporter activity
FZ025_07495	COG4771	TonB-dependent receptor
FZ025_07515	COG1051	belongs to the nudix hydrolase family
FZ025_07535	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FZ025_07540	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
FZ025_07555	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FZ025_07560	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FZ025_07565	COG0730	response to heat
FZ025_07575	COG0134	indole-3-glycerol-phosphate synthase activity
FZ025_07580	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FZ025_07595	COG1127	ABC transporter
FZ025_07600	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FZ025_07605	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FZ025_07620	COG2853	Lipoprotein
FZ025_07630	COG0386	Belongs to the glutathione peroxidase family
FZ025_07635	COG1322	Protein conserved in bacteria
FZ025_07640	COG0625	glutathione transferase activity
FZ025_07650	COG1285	pathogenesis
FZ025_07655	COG4191	Histidine kinase
FZ025_07660	COG4566	intracellular signal transduction
FZ025_07665	COG0531	amino acid
FZ025_07670	COG2814	Major facilitator Superfamily
FZ025_07680	COG1929	Belongs to the glycerate kinase type-1 family
FZ025_07685	COG0823	Involved in the tonB-independent uptake of proteins
FZ025_07685	COG1506	peptidase
FZ025_07685	COG4946	Tricorn protease homolog
FZ025_07695	COG4771	TonB-dependent receptor
FZ025_07705	COG1522	sequence-specific DNA binding
FZ025_07730	COG1126	abc transporter atp-binding protein
FZ025_07740	COG1473	amidohydrolase
FZ025_07745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FZ025_07750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FZ025_07760	COG0431	NADPH-dependent FMN reductase
FZ025_07765	COG4206	TonB-dependent receptor
FZ025_07775	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FZ025_07795	COG0671	phosphoesterase, PA-phosphatase related
FZ025_07805	COG1752	Esterase of the alpha-beta hydrolase superfamily
FZ025_07810	COG1522	sequence-specific DNA binding
FZ025_07815	COG3186	Phenylalanine-4-hydroxylase
FZ025_07840	COG1028	Short-chain dehydrogenase reductase Sdr
FZ025_07845	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FZ025_07855	COG1609	Transcriptional regulator
FZ025_07860	COG3507	Belongs to the glycosyl hydrolase 43 family
FZ025_07875	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FZ025_07885	COG2755	lipolytic protein G-D-S-L family
FZ025_07885	COG0657	acetylesterase activity
FZ025_07920	COG4772	TonB-dependent receptor
FZ025_07995	COG0681	Belongs to the peptidase S26 family
FZ025_08010	COG0339	signal peptide processing
FZ025_08015	COG1446	asparaginase
FZ025_08060	COG2197	response regulator
FZ025_08065	COG4585	Histidine kinase
FZ025_08100	COG4771	TonB-dependent receptor
FZ025_08115	COG1902	pentaerythritol trinitrate reductase activity
FZ025_08130	COG1309	transcriptional regulator
FZ025_08135	COG2814	Major facilitator Superfamily
FZ025_08145	COG0789	Transcriptional regulator
FZ025_08165	COG0640	Transcriptional regulator
FZ025_08195	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FZ025_08215	COG2814	Major facilitator Superfamily
FZ025_08225	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FZ025_08240	COG0756	dUTP diphosphatase activity
FZ025_08245	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FZ025_08250	COG2003	Belongs to the UPF0758 family
FZ025_08265	COG4221	oxidoreductase activity
FZ025_08275	COG2755	lipolytic protein G-D-S-L family
FZ025_08275	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FZ025_08280	COG1166	arginine decarboxylase activity
FZ025_08295	COG2960	long-chain fatty acid transporting porin activity
FZ025_08300	COG0606	chelatase, subunit chli
FZ025_08320	COG4773	Receptor
FZ025_08365	COG0840	transmembrane signaling receptor activity
FZ025_08415	COG0584	glycerophosphoryl diester phosphodiesterase
FZ025_08460	COG1136	(ABC) transporter
FZ025_08460	COG0577	efflux transmembrane transporter activity
FZ025_08465	COG4591	ABC-type transport system involved in lipoprotein release permease component
FZ025_08495	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FZ025_08520	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FZ025_08535	COG2826	transposase and inactivated derivatives, IS30 family
FZ025_08555	COG4807	Protein conserved in bacteria
FZ025_08570	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FZ025_08620	COG1181	Belongs to the D-alanine--D-alanine ligase family
FZ025_08630	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FZ025_08640	COG0318	PFAM AMP-dependent synthetase and ligase
FZ025_08650	COG0583	DNA-binding transcription factor activity
FZ025_08665	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FZ025_08670	COG0596	Alpha beta hydrolase
FZ025_08685	COG3177	Filamentation induced by cAMP protein fic
FZ025_08690	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FZ025_08700	COG0612	Peptidase, M16
FZ025_08710	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FZ025_08725	COG1119	ATPase activity
FZ025_08740	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FZ025_08750	COG1335	isochorismatase
FZ025_08765	COG1733	regulation of RNA biosynthetic process
FZ025_08775	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FZ025_08795	COG0594	ribonuclease P activity
FZ025_08800	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FZ025_08810	COG0592	DNA-directed DNA polymerase activity
FZ025_08815	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FZ025_08820	COG0187	DNA topoisomerase II activity
FZ025_08825	COG1266	CAAX protease self-immunity
FZ025_08830	COG0501	Belongs to the peptidase M48B family
FZ025_08860	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FZ025_08870	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FZ025_08885	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FZ025_08890	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FZ025_08895	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FZ025_08900	COG0493	'glutamate synthase
FZ025_08905	COG0067	glutamate synthase
FZ025_08905	COG0070	glutamate synthase
FZ025_08905	COG0069	glutamate synthase activity
FZ025_08935	COG1111	helicase
FZ025_08935	COG1205	dead DEAH box helicase
FZ025_08980	COG2271	Major facilitator Superfamily
FZ025_09040	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FZ025_09075	COG0183	Belongs to the thiolase family
FZ025_09085	COG2032	superoxide dismutase activity
FZ025_09090	COG2032	superoxide dismutase activity
FZ025_09115	COG2204	response regulator
FZ025_09120	COG3852	Histidine kinase
FZ025_09125	COG0004	ammonium transporteR
FZ025_09130	COG0347	Belongs to the P(II) protein family
FZ025_09135	COG0174	glutamine synthetase
FZ025_09140	COG1968	undecaprenyl-diphosphatase activity
FZ025_09165	COG2050	protein possibly involved in aromatic compounds catabolism
FZ025_09170	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FZ025_09180	COG2062	phosphohistidine phosphatase, SixA
FZ025_09185	COG1192	Involved in chromosome partitioning
FZ025_09235	COG1028	Short-chain dehydrogenase reductase Sdr
FZ025_09250	COG2207	Transcriptional regulator
FZ025_09255	COG4221	oxidoreductase activity
FZ025_09265	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FZ025_09275	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
FZ025_09285	COG1435	thymidine kinase activity
FZ025_09290	COG0210	DNA helicase
FZ025_09300	COG0752	glycyl-tRNA synthetase alpha subunit
FZ025_09305	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FZ025_09310	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FZ025_09310	COG0519	Catalyzes the synthesis of GMP from XMP
FZ025_09320	COG0805	protein transport
FZ025_09330	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FZ025_09360	COG0180	Tryptophanyl-tRNA synthetase
FZ025_09385	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FZ025_09425	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FZ025_09430	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FZ025_09430	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FZ025_09440	COG3228	Belongs to the MtfA family
FZ025_09450	COG2814	Major facilitator Superfamily
FZ025_09465	COG1902	pentaerythritol trinitrate reductase activity
FZ025_09475	COG1028	Short-chain dehydrogenase reductase Sdr
FZ025_09525	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FZ025_09535	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FZ025_09540	COG0179	Fumarylacetoacetate (FAA) hydrolase
FZ025_09555	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FZ025_09565	COG0745	RESPONSE REGULATOR receiver
FZ025_09570	COG2205	protein histidine kinase activity
FZ025_09605	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FZ025_09610	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FZ025_09615	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FZ025_09625	COG1764	response to oxidative stress
FZ025_09630	COG1846	Transcriptional regulator
FZ025_09635	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FZ025_09650	COG0523	cobalamin synthesis protein
FZ025_09665	COG3245	cytochrome
FZ025_09675	COG1960	acyl-CoA dehydrogenase activity
FZ025_09680	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FZ025_09710	COG0697	spore germination
FZ025_09730	COG0577	efflux transmembrane transporter activity
FZ025_09735	COG1136	(ABC) transporter
FZ025_09755	COG4773	Receptor
FZ025_09765	COG0753	catalase activity
FZ025_09780	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FZ025_09810	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FZ025_09875	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FZ025_09880	COG2224	Isocitrate lyase
FZ025_09885	COG2963	transposase activity
FZ025_09910	COG3706	GGDEF domain
FZ025_09935	COG2826	transposase and inactivated derivatives, IS30 family
FZ025_09955	COG0659	secondary active sulfate transmembrane transporter activity
FZ025_09985	COG0656	L-ascorbic acid biosynthetic process
FZ025_10000	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FZ025_10005	COG2130	NADP-dependent
FZ025_10020	COG1187	pseudouridine synthase activity
FZ025_10040	COG0084	hydrolase, TatD family'
FZ025_10060	COG2323	membrane
FZ025_10070	COG0408	coproporphyrinogen oxidase activity
FZ025_10085	COG1271	oxidase subunit
FZ025_10090	COG1294	oxidase, subunit
FZ025_10120	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FZ025_10135	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FZ025_10160	COG1028	Short-chain dehydrogenase reductase Sdr
FZ025_10170	COG0463	Glycosyl transferase, family 2
FZ025_10180	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FZ025_10185	COG3100	YcgL domain-containing protein
FZ025_10195	COG3387	PFAM Glycoside hydrolase 15-related
FZ025_10200	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FZ025_10215	COG2826	transposase and inactivated derivatives, IS30 family
FZ025_10240	COG0583	DNA-binding transcription factor activity
FZ025_10245	COG0667	Aldo Keto reductase
FZ025_10265	COG2937	Belongs to the GPAT DAPAT family
FZ025_10280	COG1609	Transcriptional regulator
FZ025_10300	COG0284	orotidine-5'-phosphate decarboxylase activity
FZ025_10310	COG1252	NADH dehydrogenase
FZ025_10325	COG3132	Protein of unknown function, DUF480
FZ025_10345	COG0729	surface antigen
FZ025_10350	COG2911	Protein conserved in bacteria
FZ025_10360	COG2826	transposase and inactivated derivatives, IS30 family
FZ025_10460	COG2826	transposase and inactivated derivatives, IS30 family
FZ025_10480	COG4974	Belongs to the 'phage' integrase family
FZ025_10505	COG3265	gluconokinase activity
FZ025_10520	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FZ025_10525	COG5001	Diguanylate cyclase
FZ025_10535	COG2205	protein histidine kinase activity
FZ025_10540	COG0457	Tetratricopeptide repeat
FZ025_10560	COG1971	Probably functions as a manganese efflux pump
FZ025_10580	COG0477	Major facilitator Superfamily
FZ025_10585	COG1011	Hydrolase
FZ025_10600	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FZ025_10610	COG4948	Mandelate Racemase Muconate Lactonizing
FZ025_10615	COG2808	Putative FMN-binding domain
FZ025_10620	COG4977	sequence-specific DNA binding
FZ025_10620	COG1917	Cupin 2, conserved barrel domain protein
FZ025_10625	COG0154	amidase activity
FZ025_10650	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FZ025_10655	COG1012	belongs to the aldehyde dehydrogenase family
FZ025_10660	COG0583	DNA-binding transcription factor activity
FZ025_10665	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FZ025_10670	COG0277	FAD linked oxidase domain protein
FZ025_10670	COG0247	lactate metabolic process
FZ025_10680	COG5383	Protein conserved in bacteria
FZ025_10700	COG2091	lysine biosynthetic process via aminoadipic acid
FZ025_10705	COG0357	Ribosomal RNA small subunit methyltransferase G
FZ025_10710	COG1192	Involved in chromosome partitioning
FZ025_10715	COG1475	DNA binding
FZ025_10725	COG0463	Glycosyl transferase, family 2
FZ025_10745	COG0589	response to stress
FZ025_10780	COG0210	DNA helicase
FZ025_10785	COG0583	DNA-binding transcription factor activity
FZ025_10790	COG0477	Major facilitator Superfamily
FZ025_10805	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FZ025_10810	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FZ025_10825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FZ025_10845	COG0037	tRNA processing
FZ025_10850	COG2974	May be involved in recombination
FZ025_10860	COG0842	Transport permease protein
FZ025_10865	COG1131	(ABC) transporter
FZ025_10870	COG0543	2 iron, 2 sulfur cluster binding
FZ025_10870	COG0633	Ferredoxin
FZ025_10880	COG4555	ABC transporter
FZ025_10900	COG0625	glutathione transferase activity
FZ025_10935	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FZ025_10955	COG1199	ATP-dependent helicase activity
FZ025_11005	COG0628	permease
FZ025_11065	COG0714	Associated with various cellular activities
FZ025_11100	COG1522	sequence-specific DNA binding
FZ025_11105	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FZ025_11120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FZ025_11125	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FZ025_11165	COG1028	Short-chain dehydrogenase reductase Sdr
FZ025_11185	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FZ025_11210	COG2207	Transcriptional regulator
FZ025_11220	COG4773	Receptor
FZ025_11225	COG2814	Major facilitator Superfamily
FZ025_11230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FZ025_11240	COG0531	amino acid
FZ025_11320	COG0697	spore germination
FZ025_11325	COG1113	amino acid transport
FZ025_11340	COG2207	Transcriptional regulator
FZ025_11370	COG0513	Belongs to the DEAD box helicase family
FZ025_11395	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FZ025_11405	COG3483	tryptophan 2,3-dioxygenase activity
FZ025_11410	COG3104	oligopeptide transport
FZ025_11430	COG2852	Protein conserved in bacteria
FZ025_11455	COG1320	monovalent cation:proton antiporter activity
FZ025_11460	COG2212	antiporter activity
FZ025_11465	COG1863	multisubunit Na H antiporter MnhE subunit
FZ025_11470	COG0651	ATP synthesis coupled electron transport
FZ025_11475	COG1006	Multisubunit Na H antiporter MnhC subunit
FZ025_11480	COG2111	Na H antiporter
FZ025_11480	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FZ025_11485	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FZ025_11510	COG2814	Major facilitator Superfamily
FZ025_11515	COG4942	peptidase
FZ025_11540	COG0484	heat shock protein binding
FZ025_11555	COG1597	lipid kinase activity
FZ025_11580	COG1196	nuclear chromosome segregation
FZ025_11580	COG3264	Mechanosensitive ion channel
FZ025_11610	COG2354	Protein conserved in bacteria
FZ025_11615	COG3706	GGDEF domain
FZ025_11620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FZ025_11640	COG0741	lytic transglycosylase activity
FZ025_11655	COG0612	Peptidase, M16
FZ025_11670	COG0531	amino acid
FZ025_11685	COG3275	phosphorelay sensor kinase activity
FZ025_11690	COG3279	Response regulator of the LytR AlgR family
FZ025_11715	COG2124	cytochrome p450
FZ025_11715	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FZ025_11735	COG0745	RESPONSE REGULATOR receiver
FZ025_11750	COG2885	chlorophyll binding
FZ025_11750	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FZ025_11770	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FZ025_11790	COG0028	Belongs to the TPP enzyme family
FZ025_11795	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FZ025_11795	COG1648	precorrin-2 dehydrogenase activity
FZ025_11805	COG1116	anion transmembrane transporter activity
FZ025_11805	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FZ025_11820	COG2223	nitrite transmembrane transporter activity
FZ025_11825	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FZ025_11830	COG2146	nitrite reductase [NAD(P)H] activity
FZ025_11835	COG0243	molybdopterin cofactor binding
FZ025_11860	COG1640	4-alpha-glucanotransferase
FZ025_11865	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FZ025_11885	COG0745	RESPONSE REGULATOR receiver
FZ025_11910	COG0181	hydroxymethylbilane synthase activity
FZ025_11925	COG1733	regulation of RNA biosynthetic process
FZ025_11940	COG1505	serine-type exopeptidase activity
FZ025_11965	COG2832	Protein of unknown function (DUF454)
FZ025_11995	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FZ025_12015	COG2226	methyltransferase
FZ025_12020	COG0308	aminopeptidase N
FZ025_12025	COG0508	dehydrogenase complex catalyzes the overall conversion of
FZ025_12025	COG0596	Alpha beta hydrolase
FZ025_12050	COG2010	Cytochrome c
FZ025_12060	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FZ025_12080	COG0730	response to heat
FZ025_12085	COG1012	belongs to the aldehyde dehydrogenase family
FZ025_12095	COG1213	nucleotidyl transferase
FZ025_12105	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
FZ025_12105	COG0028	Belongs to the TPP enzyme family
FZ025_12120	COG3284	Transcriptional regulator
FZ025_12130	COG1077	Cell shape determining protein MreB Mrl
FZ025_12135	COG1792	Involved in formation and maintenance of cell shape
FZ025_12150	COG0772	Belongs to the SEDS family
FZ025_12160	COG5434	Belongs to the glycosyl hydrolase 28 family
FZ025_12165	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FZ025_12170	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FZ025_12175	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FZ025_12180	COG1012	belongs to the aldehyde dehydrogenase family
FZ025_12185	COG2951	lytic endotransglycosylase activity
FZ025_12195	COG1686	Belongs to the peptidase S11 family
FZ025_12220	COG2921	Belongs to the UPF0250 family
FZ025_12230	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FZ025_12270	COG1090	epimerase
FZ025_12280	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FZ025_12285	COG0673	inositol 2-dehydrogenase activity
FZ025_12290	COG2823	Periplasmic or secreted lipoprotein
FZ025_12300	COG2202	Pas domain
FZ025_12300	COG2205	protein histidine kinase activity
FZ025_12305	COG0784	Response regulator, receiver
FZ025_12310	COG4191	Histidine kinase
FZ025_12320	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FZ025_12325	COG1028	Short-chain dehydrogenase reductase Sdr
FZ025_12345	COG3250	beta-galactosidase activity
FZ025_12360	COG2188	Transcriptional regulator
FZ025_12365	COG0738	Major facilitator superfamily
FZ025_12370	COG1609	Transcriptional regulator
FZ025_12375	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FZ025_12380	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FZ025_12440	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FZ025_12450	COG2207	Transcriptional regulator
FZ025_12485	COG2205	protein histidine kinase activity
FZ025_12490	COG0745	RESPONSE REGULATOR receiver
FZ025_12505	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FZ025_12510	COG3791	Glutathione-dependent formaldehyde-activating
FZ025_12520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FZ025_12530	COG0697	spore germination
FZ025_12540	COG1307	EDD domain protein, DegV family
FZ025_12580	COG3459	Glycosyltransferase 36 associated
FZ025_12585	COG2826	transposase and inactivated derivatives, IS30 family
FZ025_12590	COG3459	Glycosyltransferase 36 associated
FZ025_12610	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FZ025_12625	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FZ025_12630	COG0726	polysaccharide deacetylase
FZ025_12690	COG1162	GTPase activity
FZ025_12710	COG4206	TonB-dependent receptor
FZ025_12715	COG2211	Major facilitator Superfamily
FZ025_12725	COG1028	Short-chain dehydrogenase reductase Sdr
FZ025_12730	COG2851	Citrate transporter
FZ025_12745	COG0642	Histidine kinase
FZ025_12750	COG1840	ABC-type Fe3 transport system, periplasmic component
FZ025_12770	COG4191	Histidine kinase
FZ025_12785	COG1301	dicarboxylic acid transport
FZ025_12835	COG1560	Kdo2-lipid A biosynthetic process
FZ025_12840	COG1519	Transferase
FZ025_12845	COG1538	Outer membrane efflux protein
FZ025_12850	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FZ025_12860	COG3706	GGDEF domain
FZ025_12865	COG0473	3-isopropylmalate dehydrogenase activity
FZ025_12870	COG0066	3-isopropylmalate dehydratase activity
FZ025_12885	COG4106	trans-aconitate 2-methyltransferase activity
FZ025_12890	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FZ025_12920	COG0405	Gamma-glutamyltransferase
FZ025_12925	COG1506	peptidase
FZ025_12925	COG4946	Tricorn protease homolog
FZ025_12925	COG0823	Involved in the tonB-independent uptake of proteins
FZ025_12930	COG0840	transmembrane signaling receptor activity
FZ025_12955	COG4206	TonB-dependent receptor
FZ025_12965	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FZ025_12975	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FZ025_12995	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FZ025_13015	COG0586	Pfam SNARE associated Golgi protein
FZ025_13025	COG1028	Short-chain dehydrogenase reductase Sdr
FZ025_13030	COG1940	carbohydrate kinase activity
FZ025_13035	COG0346	lactoylglutathione lyase activity
FZ025_13050	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FZ025_13060	COG4206	TonB-dependent receptor
FZ025_13070	COG2010	Cytochrome c
FZ025_13080	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FZ025_13095	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FZ025_13110	COG1773	rubredoxin
FZ025_13115	COG2912	Transglutaminase-like superfamily
FZ025_13125	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FZ025_13135	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FZ025_13165	COG3079	Belongs to the UPF0149 family
FZ025_13170	COG0006	proline dipeptidase activity
FZ025_13175	COG0006	proline dipeptidase activity
FZ025_13190	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FZ025_13195	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FZ025_13200	COG0346	lactoylglutathione lyase activity
FZ025_13205	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FZ025_13210	COG1561	YicC-like family, N-terminal region
FZ025_13220	COG0848	biopolymer transport protein
FZ025_13235	COG2832	Protein of unknown function (DUF454)
FZ025_13260	COG3712	iron ion homeostasis
FZ025_13270	COG0194	GDP metabolic process
FZ025_13275	COG1758	RNA polymerase activity
FZ025_13280	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FZ025_13290	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FZ025_13300	COG0254	rRNA binding
FZ025_13325	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FZ025_13370	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FZ025_13375	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FZ025_13385	COG2205	protein histidine kinase activity
FZ025_13390	COG0745	RESPONSE REGULATOR receiver
FZ025_13405	COG0277	FAD linked oxidase domain protein
FZ025_13410	COG1988	membrane-bound metal-dependent
FZ025_13450	COG2001	Belongs to the MraZ family
FZ025_13455	COG0275	rRNA processing
FZ025_13460	COG3116	cell division
FZ025_13475	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FZ025_13495	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FZ025_13500	COG1181	Belongs to the D-alanine--D-alanine ligase family
FZ025_13505	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FZ025_13515	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FZ025_13520	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FZ025_13530	COG0739	heme binding
FZ025_13535	COG0653	protein targeting
FZ025_13545	COG0494	nUDIX hydrolase
FZ025_13555	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FZ025_13615	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FZ025_13640	COG0515	serine threonine protein kinase
FZ025_13655	COG0488	(ABC) transporter
FZ025_13670	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FZ025_13680	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FZ025_13680	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FZ025_13695	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FZ025_13700	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FZ025_13710	COG0714	Associated with various cellular activities
FZ025_13740	COG1301	dicarboxylic acid transport
FZ025_13745	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FZ025_13795	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FZ025_13800	COG4149	molybdate abc transporter
FZ025_13805	COG0725	ABC transporter, periplasmic molybdate-binding protein
FZ025_13815	COG0640	Transcriptional regulator
FZ025_13840	COG3047	cAMP biosynthetic process
FZ025_13850	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FZ025_13860	COG3657	addiction module killer protein
FZ025_13870	COG0210	DNA helicase
FZ025_13875	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FZ025_13880	COG0736	holo-[acyl-carrier-protein] synthase activity
FZ025_13925	COG1475	DNA binding
FZ025_13930	COG5489	Protein of unknown function (DUF736)
FZ025_13975	COG1192	Involved in chromosome partitioning
FZ025_14005	COG0583	DNA-binding transcription factor activity
FZ025_14010	COG2814	Major facilitator Superfamily
FZ025_14015	COG1902	pentaerythritol trinitrate reductase activity
FZ025_14020	COG0583	DNA-binding transcription factor activity
FZ025_14030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FZ025_14045	COG0583	DNA-binding transcription factor activity
FZ025_14065	COG4962	Type ii secretion system protein e
FZ025_14070	COG3838	Conjugal transfer protein Trbc
FZ025_14080	COG3451	type IV secretory pathway VirB4
FZ025_14095	COG3846	protein secretion by the type IV secretion system
FZ025_14105	COG3504	Conjugal transfer protein
FZ025_14135	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FZ025_14140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FZ025_14175	COG0469	pyruvate kinase activity
FZ025_14180	COG3588	fructose-bisphosphate aldolase
FZ025_14185	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FZ025_14190	COG2252	PERMEase
FZ025_14200	COG1957	nucleoside hydrolase
FZ025_14235	COG4771	TonB-dependent receptor
FZ025_14245	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FZ025_14260	COG0277	FAD linked oxidase domain protein
FZ025_14265	COG1132	(ABC) transporter
FZ025_14270	COG2897	thiosulfate sulfurtransferase activity
FZ025_14290	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FZ025_14310	COG2072	flavoprotein involved in K transport
FZ025_14315	COG2351	hydroxyisourate hydrolase activity
FZ025_14325	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FZ025_14370	COG0840	transmembrane signaling receptor activity
FZ025_14375	COG0431	NADPH-dependent FMN reductase
FZ025_14405	COG0175	sulfate reduction
FZ025_14410	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FZ025_14415	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FZ025_14425	COG2895	sulfate adenylyltransferase (ATP) activity
FZ025_14425	COG0529	Catalyzes the synthesis of activated sulfate
FZ025_14430	COG0438	transferase activity, transferring glycosyl groups
FZ025_14450	COG1115	amino acid carrier protein
FZ025_14460	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FZ025_14470	COG1609	Transcriptional regulator
FZ025_14485	COG0179	Fumarylacetoacetate (FAA) hydrolase
FZ025_14500	COG3273	potassium ion transport
FZ025_14500	COG0471	metal ion transport
FZ025_14505	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FZ025_14545	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FZ025_14550	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FZ025_14565	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FZ025_14570	COG1404	Belongs to the peptidase S8 family
FZ025_14605	COG0544	peptidyl-prolyl cis-trans isomerase activity
FZ025_14610	COG0740	serine-type endopeptidase activity
FZ025_14615	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FZ025_14655	COG2801	Transposase and inactivated derivatives
FZ025_14660	COG2826	transposase and inactivated derivatives, IS30 family
FZ025_14750	COG1388	LysM domain
FZ025_14750	COG3942	CHAP domain
FZ025_14755	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FZ025_14765	COG0328	RNA-DNA hybrid ribonuclease activity
FZ025_14770	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FZ025_14775	COG0631	protein serine/threonine phosphatase activity
FZ025_14785	COG0583	DNA-binding transcription factor activity
FZ025_14795	COG1028	Short-chain dehydrogenase reductase Sdr
FZ025_14815	COG0859	PFAM glycosyl transferase family 9
FZ025_14825	COG1234	tRNA 3'-trailer cleavage
FZ025_14830	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FZ025_14845	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FZ025_14850	COG0314	molybdopterin synthase activity
FZ025_14860	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FZ025_14870	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FZ025_14880	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FZ025_14915	COG4680	protein conserved in bacteria
FZ025_14940	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FZ025_14950	COG0537	adenosine 5'-monophosphoramidase activity
FZ025_14970	COG0714	Associated with various cellular activities
FZ025_14995	COG1399	metal-binding, possibly nucleic acid-binding protein
FZ025_15000	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FZ025_15005	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FZ025_15010	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FZ025_15015	COG1028	Short-chain dehydrogenase reductase Sdr
FZ025_15030	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FZ025_15035	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FZ025_15040	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FZ025_15065	COG4115	mRNA cleavage
FZ025_15070	COG2161	toxin-antitoxin pair type II binding
FZ025_15080	COG0640	Transcriptional regulator
FZ025_15115	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FZ025_15120	COG0372	Belongs to the citrate synthase family
FZ025_15145	COG3609	addiction module antidote protein, CC2985 family
FZ025_15165	COG4771	TonB-dependent receptor
FZ025_15175	COG2373	Large extracellular alpha-helical protein
FZ025_15200	COG1136	(ABC) transporter
FZ025_15230	COG0641	radical SAM
FZ025_15270	COG1136	(ABC) transporter
FZ025_15270	COG0577	efflux transmembrane transporter activity
FZ025_15290	COG2204	response regulator
FZ025_15300	COG4953	penicillin-binding protein 1C
FZ025_15310	COG0678	peroxiredoxin activity
FZ025_15320	COG0484	heat shock protein binding
FZ025_15325	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FZ025_15345	COG1199	ATP-dependent helicase activity
FZ025_15375	COG0189	ligase activity
FZ025_15390	COG0835	chemotaxis
FZ025_15395	COG0840	transmembrane signaling receptor activity
FZ025_15405	COG2201	protein-glutamate methylesterase activity
FZ025_15425	COG1446	asparaginase
FZ025_15475	COG3537	Alpha-1,2-mannosidase
FZ025_15485	COG1472	Belongs to the glycosyl hydrolase 3 family
FZ025_15495	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FZ025_15500	COG3858	chitin binding
FZ025_15500	COG1388	LysM domain
FZ025_15515	COG0837	glucose binding
FZ025_15520	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FZ025_15530	COG0494	nUDIX hydrolase
FZ025_15540	COG3956	TIGRFAM MazG family protein
FZ025_15545	COG1742	UPF0060 membrane protein
FZ025_15555	COG0330	HflC and HflK could
FZ025_15570	COG0604	alcohol dehydrogenase
FZ025_15575	COG0330	HflC and HflK could
FZ025_15580	COG0330	HflC and HflK could
FZ025_15590	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FZ025_15640	COG1187	pseudouridine synthase activity
FZ025_15700	COG1132	(ABC) transporter
FZ025_15760	COG0825	malonyl-CoA metabolic process
FZ025_15770	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FZ025_15780	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FZ025_15790	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FZ025_15800	COG0750	zinc metalloprotease
FZ025_15805	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FZ025_15810	COG0575	Belongs to the CDS family
FZ025_15815	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FZ025_15830	COG3706	GGDEF domain
FZ025_15835	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FZ025_15840	COG0052	Belongs to the universal ribosomal protein uS2 family
FZ025_15875	COG0024	Methionine aminopeptidase
FZ025_15890	COG1393	Belongs to the ArsC family
FZ025_15895	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FZ025_15900	COG0367	asparagine synthase
FZ025_15940	COG1566	PFAM secretion protein HlyD family protein
FZ025_15945	COG2814	Major facilitator Superfamily
FZ025_15970	COG3590	peptidase
FZ025_16005	COG0745	RESPONSE REGULATOR receiver
FZ025_16040	COG4794	Type iii secretion
FZ025_16065	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FZ025_16090	COG1317	bacterial-type flagellum organization
FZ025_16110	COG2207	Transcriptional regulator
FZ025_16140	COG1028	Short-chain dehydrogenase reductase Sdr
FZ025_16160	COG0625	glutathione transferase activity
FZ025_16170	COG0475	glutathione-regulated potassium exporter activity
FZ025_16180	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FZ025_16205	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FZ025_16210	COG2070	2-Nitropropane dioxygenase
FZ025_16220	COG0228	four-way junction DNA binding
FZ025_16225	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FZ025_16235	COG0335	large ribosomal subunit rRNA binding
FZ025_16240	COG0534	Mate efflux family protein
FZ025_16255	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FZ025_16265	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FZ025_16280	COG3250	beta-galactosidase activity
FZ025_16285	COG3867	Arabinogalactan endo-beta-1,4-galactanase
FZ025_16300	COG2855	membrane
FZ025_16310	COG1024	Enoyl-CoA hydratase
FZ025_16310	COG1250	3-hydroxyacyl-CoA dehydrogenase
FZ025_16325	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FZ025_16335	COG0681	Belongs to the peptidase S26 family
FZ025_16350	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FZ025_16360	COG0784	Response regulator, receiver
FZ025_16360	COG2198	Histidine kinase
FZ025_16360	COG5002	protein histidine kinase activity
FZ025_16380	COG1472	Belongs to the glycosyl hydrolase 3 family
FZ025_16390	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FZ025_16395	COG1278	Cold shock
FZ025_16430	COG0438	transferase activity, transferring glycosyl groups
FZ025_16435	COG0438	transferase activity, transferring glycosyl groups
FZ025_16470	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FZ025_16480	COG1960	acyl-CoA dehydrogenase activity
FZ025_16530	COG1570	exodeoxyribonuclease VII activity
FZ025_16535	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FZ025_16540	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FZ025_16540	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FZ025_16545	COG0802	atpase or kinase
FZ025_16550	COG0860	N-Acetylmuramoyl-L-alanine amidase
FZ025_16555	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FZ025_16575	COG1028	Short-chain dehydrogenase reductase Sdr
FZ025_16595	COG2081	HI0933 family
FZ025_16600	COG4681	YaeQ
FZ025_16605	COG0564	pseudouridine synthase activity
FZ025_16615	COG0625	glutathione transferase activity
FZ025_16625	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FZ025_16650	COG0513	Belongs to the DEAD box helicase family
FZ025_16675	COG2207	Transcriptional regulator
FZ025_16685	COG4585	Histidine kinase
FZ025_16690	COG2197	response regulator
FZ025_16735	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FZ025_16740	COG1846	Transcriptional regulator
FZ025_16745	COG0339	signal peptide processing
FZ025_16755	COG0386	Belongs to the glutathione peroxidase family
FZ025_16810	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FZ025_16815	COG0084	hydrolase, TatD family'
FZ025_16830	COG1960	acyl-CoA dehydrogenase activity
FZ025_16845	COG0305	Participates in initiation and elongation during chromosome replication
FZ025_16855	COG0784	Response regulator, receiver
FZ025_16855	COG4191	Histidine kinase
FZ025_16860	COG2204	response regulator
FZ025_16865	COG2204	response regulator
FZ025_16870	COG0415	Belongs to the DNA photolyase family
FZ025_16885	COG0583	DNA-binding transcription factor activity
FZ025_16900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FZ025_16920	COG3706	GGDEF domain
FZ025_16935	COG1404	Belongs to the peptidase S8 family
FZ025_16945	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FZ025_16950	COG1862	Preprotein translocase
FZ025_16960	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FZ025_16990	COG1509	lysine 2,3-aminomutase activity
FZ025_17005	COG0402	S-adenosylhomocysteine deaminase activity
FZ025_17025	COG5434	Belongs to the glycosyl hydrolase 28 family
FZ025_17030	COG4677	pectinesterase activity
FZ025_17040	COG4302	ethanolamine ammonia-lyase activity
FZ025_17045	COG4303	Ethanolamine ammonia lyase large subunit
FZ025_17065	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FZ025_17075	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FZ025_17090	COG2166	iron-sulfur cluster assembly
FZ025_17105	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FZ025_17110	COG0137	argininosuccinate synthase activity
FZ025_17125	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FZ025_17135	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FZ025_17140	COG0165	Argininosuccinate lyase
FZ025_17155	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FZ025_17175	COG1136	(ABC) transporter
FZ025_17190	COG1668	transmembrane transport
FZ025_17195	COG4555	ABC transporter
FZ025_17240	COG1294	oxidase, subunit
FZ025_17250	COG4988	ABC transporter
FZ025_17255	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FZ025_17260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FZ025_17285	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FZ025_17305	COG4133	protoheme IX ABC transporter activity
FZ025_17310	COG0436	Aminotransferase
FZ025_17330	COG1187	pseudouridine synthase activity
FZ025_17335	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FZ025_17340	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FZ025_17345	COG2350	Protein conserved in bacteria
FZ025_17370	COG2182	Extracellular solute-binding protein
FZ025_17380	COG0395	ABC-type sugar transport system, permease component
FZ025_17390	COG0800	Aldolase
FZ025_17395	COG0129	dihydroxy-acid dehydratase activity
FZ025_17410	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FZ025_17415	COG3842	ATPase activity
FZ025_17430	COG2009	succinate dehydrogenase
FZ025_17435	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FZ025_17460	COG4591	ABC-type transport system involved in lipoprotein release permease component
FZ025_17475	COG1289	transmembrane transporter activity
FZ025_17490	COG0658	competence protein
FZ025_17490	COG2333	competence protein COMEC
FZ025_17495	COG0811	peptide transport
FZ025_17505	COG1132	(ABC) transporter
FZ025_17535	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FZ025_17535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FZ025_17545	COG0784	Response regulator, receiver
FZ025_17545	COG4191	Histidine kinase
FZ025_17550	COG2183	response to ionizing radiation
FZ025_17555	COG0784	Response regulator, receiver
FZ025_17555	COG2205	protein histidine kinase activity
FZ025_17575	COG0604	alcohol dehydrogenase
FZ025_17595	COG3246	L-lysine catabolic process to acetate
FZ025_17600	COG0583	DNA-binding transcription factor activity
FZ025_17605	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FZ025_17615	COG1024	Enoyl-CoA hydratase
FZ025_17625	COG1454	alcohol dehydrogenase
FZ025_17635	COG2124	cytochrome p450
FZ025_17720	COG5002	protein histidine kinase activity
FZ025_17720	COG5000	phosphorelay sensor kinase activity
FZ025_17730	COG1132	(ABC) transporter
FZ025_17750	COG5001	Diguanylate cyclase
FZ025_17775	COG2850	peptidyl-arginine hydroxylation
FZ025_17815	COG1131	(ABC) transporter
FZ025_17820	COG1725	Transcriptional regulator
FZ025_17830	COG0386	Belongs to the glutathione peroxidase family
FZ025_17845	COG2900	Belongs to the SlyX family
FZ025_17855	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FZ025_17855	COG2755	lipolytic protein G-D-S-L family
FZ025_17865	COG1410	methionine synthase
FZ025_17865	COG0646	methionine synthase
FZ025_17870	COG0646	methionine synthase
FZ025_17870	COG1410	methionine synthase
FZ025_17880	COG1960	acyl-CoA dehydrogenase activity
FZ025_17885	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FZ025_17900	COG2902	Dehydrogenase
FZ025_17950	COG2925	Exonuclease
FZ025_17960	COG3844	kynureninase activity
FZ025_17975	COG0288	reversible hydration of carbon dioxide
FZ025_18000	COG0316	Belongs to the HesB IscA family
FZ025_18005	COG0582	viral genome integration into host DNA
FZ025_18010	COG0582	viral genome integration into host DNA
FZ025_18025	COG3177	Filamentation induced by cAMP protein fic
FZ025_18030	COG0583	DNA-binding transcription factor activity
FZ025_18035	COG2814	Major facilitator Superfamily
FZ025_18080	COG0359	binds to the 23S rRNA
FZ025_18090	COG3115	cell septum assembly
FZ025_18095	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FZ025_18100	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FZ025_18120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FZ025_18130	COG1253	flavin adenine dinucleotide binding
FZ025_18140	COG0306	phosphate transporter
FZ025_18160	COG0504	CTP synthase activity
FZ025_18180	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FZ025_18185	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FZ025_18200	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FZ025_18210	COG1238	metal cluster binding
FZ025_18225	COG1534	Rna-binding protein
FZ025_18235	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FZ025_18240	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FZ025_18250	COG1923	regulation of RNA biosynthetic process
FZ025_18255	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FZ025_18260	COG0477	Major facilitator Superfamily
FZ025_18265	COG1546	Belongs to the CinA family
FZ025_18270	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FZ025_18275	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FZ025_18280	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FZ025_18285	COG2137	regulation of response to DNA damage stimulus
FZ025_18290	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FZ025_18295	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FZ025_18345	COG1741	Belongs to the pirin family
FZ025_18350	COG0583	DNA-binding transcription factor activity
FZ025_18375	COG0352	thiamine-phosphate diphosphorylase activity
FZ025_18375	COG0351	phosphomethylpyrimidine kinase
FZ025_18390	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FZ025_18395	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FZ025_18405	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FZ025_18420	COG0366	Alpha amylase catalytic
FZ025_18430	COG1082	Xylose isomerase domain protein TIM barrel
FZ025_18440	COG2190	(PTS) system
FZ025_18440	COG2211	Major facilitator Superfamily
FZ025_18475	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FZ025_18480	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FZ025_18485	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FZ025_18495	COG0072	phenylalanine-tRNA ligase activity
FZ025_18495	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FZ025_18500	COG0776	regulation of translation
FZ025_18520	COG1530	ribonuclease E activity
FZ025_18550	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FZ025_18550	COG0316	Belongs to the HesB IscA family
FZ025_18570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FZ025_18590	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FZ025_18595	COG2957	Belongs to the agmatine deiminase family
FZ025_18605	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FZ025_18610	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FZ025_18615	COG0539	negative regulation of cytoplasmic translation
FZ025_18620	COG0776	regulation of translation
FZ025_18630	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FZ025_18635	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FZ025_18645	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FZ025_18650	COG0183	Belongs to the thiolase family
FZ025_18655	COG1250	3-hydroxyacyl-CoA dehydrogenase
FZ025_18655	COG1024	Enoyl-CoA hydratase
FZ025_18665	COG0105	UTP biosynthetic process
FZ025_18680	COG1426	Protein conserved in bacteria
FZ025_18690	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FZ025_18700	COG0746	molybdenum cofactor guanylyltransferase activity
FZ025_18710	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FZ025_18715	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FZ025_18715	COG0475	glutathione-regulated potassium exporter activity
FZ025_18730	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FZ025_18740	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FZ025_18740	COG0519	Catalyzes the synthesis of GMP from XMP
FZ025_18760	COG0736	holo-[acyl-carrier-protein] synthase activity
FZ025_18815	COG1335	isochorismatase
FZ025_18830	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FZ025_18840	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FZ025_18845	COG0277	FAD linked oxidase domain protein
FZ025_18865	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FZ025_18880	COG1024	Enoyl-CoA hydratase
FZ025_18915	COG0505	Belongs to the CarA family
FZ025_18925	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FZ025_18930	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FZ025_18945	COG4676	Protein conserved in bacteria
FZ025_18950	COG3279	Response regulator of the LytR AlgR family
FZ025_18970	COG0784	Response regulator, receiver
FZ025_18970	COG2198	Histidine kinase
FZ025_18970	COG2205	protein histidine kinase activity
FZ025_18975	COG1024	Enoyl-CoA hydratase
FZ025_18985	COG0318	PFAM AMP-dependent synthetase and ligase
FZ025_19020	COG2201	protein-glutamate methylesterase activity
FZ025_19035	COG0840	transmembrane signaling receptor activity
FZ025_19040	COG0840	transmembrane signaling receptor activity
FZ025_19040	COG0840	transmembrane signaling receptor activity
FZ025_19045	COG0840	transmembrane signaling receptor activity
FZ025_19055	COG0835	chemotaxis
FZ025_19065	COG0840	transmembrane signaling receptor activity
FZ025_19075	COG0840	transmembrane signaling receptor activity
FZ025_19085	COG0840	transmembrane signaling receptor activity
FZ025_19095	COG0745	RESPONSE REGULATOR receiver
FZ025_19110	COG1192	Involved in chromosome partitioning
FZ025_19120	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FZ025_19125	COG2198	Histidine kinase
FZ025_19125	COG0643	Histidine kinase
FZ025_19130	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FZ025_19145	COG0455	bacterial-type flagellum organization
FZ025_19165	COG1684	flagellar biosynthetic protein fliR
FZ025_19170	COG1987	bacterial-type flagellum assembly
FZ025_19180	COG3190	flagellar
FZ025_19230	COG1677	Flagellar hook-basal body complex protein FliE
FZ025_19260	COG1028	Short-chain dehydrogenase reductase Sdr
FZ025_19265	COG1028	Short-chain dehydrogenase reductase Sdr
FZ025_19270	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FZ025_19285	COG2204	response regulator
FZ025_19290	COG2201	protein-glutamate methylesterase activity
FZ025_19300	COG2197	response regulator
FZ025_19320	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FZ025_19325	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FZ025_19335	COG4786	Flagellar basal body rod
FZ025_19335	COG1256	bacterial-type flagellum assembly
FZ025_19335	COG4786	Flagellar basal body rod
FZ025_19335	COG1256	bacterial-type flagellum assembly
FZ025_19350	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FZ025_19355	COG4786	Flagellar basal body rod
FZ025_19365	COG1749	Flagellar hook protein flgE
FZ025_19370	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FZ025_19375	COG1558	bacterial-type flagellum-dependent cell motility
FZ025_19385	COG0835	chemotaxis
FZ025_19385	COG0784	Response regulator, receiver
FZ025_19430	COG1116	anion transmembrane transporter activity
FZ025_19445	COG2915	High frequency lysogenization protein hflD homolog
FZ025_19450	COG0482	sulfurtransferase activity
FZ025_19470	COG0542	response to heat
FZ025_19475	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FZ025_19480	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FZ025_19490	COG0492	ferredoxin-NADP+ reductase activity
FZ025_19495	COG1674	ftsk spoiiie
FZ025_19520	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FZ025_19525	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FZ025_19590	COG1595	DNA-templated transcription, initiation
FZ025_19640	COG2244	polysaccharide biosynthetic process
FZ025_19660	COG4106	trans-aconitate 2-methyltransferase activity
FZ025_19680	COG0297	glycogen (starch) synthase activity
FZ025_19685	COG0438	transferase activity, transferring glycosyl groups
FZ025_19705	COG1132	(ABC) transporter
FZ025_19800	COG4942	peptidase
FZ025_19835	COG0583	DNA-binding transcription factor activity
FZ025_19850	COG3504	Conjugal transfer protein
FZ025_19875	COG3451	type IV secretory pathway VirB4
FZ025_19885	COG3838	Conjugal transfer protein Trbc
FZ025_19890	COG4962	Type ii secretion system protein e
FZ025_19940	COG1566	PFAM secretion protein HlyD family protein
FZ025_19955	COG0583	DNA-binding transcription factor activity
FZ025_20000	COG0583	DNA-binding transcription factor activity
FZ025_20010	COG2807	transmembrane transport
FZ025_20035	COG0477	Major facilitator Superfamily
FZ025_20040	COG1309	transcriptional regulator
FZ025_20055	COG0640	Transcriptional regulator
FZ025_20065	COG2814	Major facilitator Superfamily
FZ025_20070	COG2826	transposase and inactivated derivatives, IS30 family
FZ025_20075	COG0583	DNA-binding transcription factor activity
FZ025_20095	COG4959	Type IV secretory pathway protease TraF
FZ025_20110	COG1192	Involved in chromosome partitioning
FZ025_20120	COG5489	Protein of unknown function (DUF736)
FZ025_20130	COG1309	transcriptional regulator
FZ025_20135	COG2814	Major facilitator Superfamily
FZ025_20175	COG2003	Belongs to the UPF0758 family
FZ025_20420	COG1074	ATP-dependent DNA helicase activity
FZ025_20430	COG2826	transposase and inactivated derivatives, IS30 family
FZ025_20475	COG2165	general secretion pathway protein
FZ025_20480	COG1450	Type ii and iii secretion system protein
FZ025_20505	COG1459	type II secretion system
FZ025_20525	COG3209	COG3209 Rhs family protein
FZ025_20570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FZ025_20575	COG2311	Membrane
FZ025_20580	COG1047	Peptidyl-prolyl cis-trans
FZ025_20585	COG0791	NLP P60 protein
FZ025_20590	COG0791	NLP P60 protein
FZ025_20595	COG1607	acyl-coa hydrolase
FZ025_20605	COG1301	dicarboxylic acid transport
FZ025_20610	COG1785	Belongs to the alkaline phosphatase family
FZ025_20620	COG0037	tRNA processing
FZ025_20625	COG1722	exodeoxyribonuclease VII activity
FZ025_20630	COG0142	geranyltranstransferase activity
FZ025_20650	COG0312	modulator of DNA gyrase
FZ025_20660	COG0312	modulator of DNA gyrase
FZ025_20670	COG1530	ribonuclease E activity
FZ025_20680	COG2968	Membrane
FZ025_20690	COG4206	TonB-dependent receptor
FZ025_20710	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FZ025_20725	COG0495	leucyl-tRNA aminoacylation
FZ025_20735	COG3118	belongs to the thioredoxin family
FZ025_20745	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FZ025_20765	COG0346	lactoylglutathione lyase activity
FZ025_20785	COG2878	Part of a membrane complex involved in electron transport
FZ025_20800	COG1595	DNA-templated transcription, initiation
FZ025_20835	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FZ025_20855	COG0251	oxidation-reduction process
FZ025_20865	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FZ025_20865	COG0392	lysyltransferase activity
FZ025_20895	COG2814	Major facilitator Superfamily
FZ025_20905	COG0583	DNA-binding transcription factor activity
FZ025_20920	COG2824	Alkylphosphonate utilization operon protein PhnA
FZ025_20925	COG1047	Peptidyl-prolyl cis-trans
FZ025_20930	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FZ025_20955	COG1028	Short-chain dehydrogenase reductase Sdr
FZ025_20990	COG2826	transposase and inactivated derivatives, IS30 family
FZ025_21050	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FZ025_21065	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FZ025_21100	COG1451	nucleotide metabolic process
FZ025_21135	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FZ025_21135	COG1703	isobutyryl-CoA mutase activity
FZ025_21135	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FZ025_21170	COG0745	RESPONSE REGULATOR receiver
FZ025_21170	COG3706	GGDEF domain
FZ025_21185	COG1960	acyl-CoA dehydrogenase activity
FZ025_21190	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FZ025_21190	COG1793	dna ligase
FZ025_21195	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FZ025_21195	COG1793	dna ligase
FZ025_21200	COG1201	RNA secondary structure unwinding
FZ025_21255	COG2080	2 iron, 2 sulfur cluster binding
FZ025_21260	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FZ025_21265	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FZ025_21270	COG0746	molybdenum cofactor guanylyltransferase activity
FZ025_21285	COG3214	Protein conserved in bacteria
FZ025_21295	COG1538	Outer membrane efflux protein
FZ025_21300	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FZ025_21310	COG1309	transcriptional regulator
FZ025_21320	COG0735	belongs to the Fur family
FZ025_21350	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FZ025_21360	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FZ025_21370	COG2198	Histidine kinase
FZ025_21370	COG0643	Histidine kinase
FZ025_21375	COG0840	transmembrane signaling receptor activity
FZ025_21380	COG0835	chemotaxis
FZ025_21385	COG4251	negative regulation of phosphorylation
FZ025_21385	COG3706	GGDEF domain
FZ025_21385	COG5001	Diguanylate cyclase
FZ025_21385	COG2203	Gaf domain
FZ025_21420	COG1741	Belongs to the pirin family
FZ025_21435	COG1966	Carbon starvation protein
FZ025_21440	COG2879	small protein
FZ025_21445	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FZ025_21465	COG1506	peptidase
FZ025_21465	COG0823	Involved in the tonB-independent uptake of proteins
FZ025_21470	COG1297	OPT oligopeptide transporter protein
FZ025_21475	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FZ025_21490	COG3152	Membrane
FZ025_21505	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FZ025_21510	COG1845	cytochrome c oxidase, subunit III
FZ025_21515	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FZ025_21525	COG2964	Protein conserved in bacteria
FZ025_21535	COG4771	TonB-dependent receptor
FZ025_21560	COG0251	oxidation-reduction process
FZ025_21570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FZ025_21585	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FZ025_21600	COG0196	riboflavin kinase activity
FZ025_21605	COG0728	peptidoglycan biosynthetic process
FZ025_21620	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FZ025_21625	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FZ025_21630	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FZ025_21635	COG0824	Thioesterase
FZ025_21645	COG1946	Acyl-CoA thioesterase
FZ025_21660	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FZ025_21670	COG3243	poly(R)-hydroxyalkanoic acid synthase
FZ025_21680	COG1183	phosphatidylcholine synthase activity
FZ025_21685	COG1028	Short-chain dehydrogenase reductase Sdr
FZ025_21700	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FZ025_21725	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FZ025_21835	COG3701	Conjugal transfer protein
FZ025_21840	COG3451	type IV secretory pathway VirB4
FZ025_21845	COG5268	conjugation
FZ025_21850	COG3838	Conjugal transfer protein Trbc
FZ025_21855	COG4962	Type ii secretion system protein e