locus-tag	class	description
KCI36_00055	COG0631	protein serine/threonine phosphatase activity
KCI36_00065	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KCI36_00090	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KCI36_00130	COG0544	peptidyl-prolyl cis-trans isomerase activity
KCI36_00180	COG0473	3-isopropylmalate dehydrogenase activity
KCI36_00205	COG0584	glycerophosphoryl diester phosphodiesterase
KCI36_00225	COG3039	Transposase
KCI36_00355	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
KCI36_00375	COG1217	gtp-binding protein TYPA
KCI36_00380	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KCI36_00390	COG0625	glutathione transferase activity
KCI36_00405	COG3781	membrane
KCI36_00415	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KCI36_00445	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
KCI36_00465	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KCI36_00490	COG3710	Transcriptional regulator
KCI36_00495	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KCI36_00505	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KCI36_00540	COG0066	3-isopropylmalate dehydratase activity
KCI36_00545	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KCI36_00570	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KCI36_00575	COG1538	Outer membrane efflux protein
KCI36_00580	COG1519	Transferase
KCI36_00585	COG1560	Kdo2-lipid A biosynthetic process
KCI36_00635	COG0308	aminopeptidase N
KCI36_00650	COG0330	HflC and HflK could
KCI36_00655	COG0330	HflC and HflK could
KCI36_00675	COG0678	peroxiredoxin activity
KCI36_00685	COG2826	transposase and inactivated derivatives, IS30 family
KCI36_00730	COG3039	Transposase
KCI36_00760	COG3829	transcription factor binding
KCI36_00795	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KCI36_00800	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KCI36_00810	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KCI36_00815	COG1028	Short-chain dehydrogenase reductase Sdr
KCI36_00840	COG1399	metal-binding, possibly nucleic acid-binding protein
KCI36_00880	COG1518	maintenance of DNA repeat elements
KCI36_00885	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KCI36_00935	COG2188	Transcriptional regulator
KCI36_00950	COG1450	Type ii and iii secretion system protein
KCI36_00965	COG3166	PFAM Fimbrial assembly family protein
KCI36_00970	COG3156	type II secretion system protein K
KCI36_00975	COG4795	General secretion pathway protein
KCI36_00980	COG2165	general secretion pathway protein
KCI36_00985	COG4970	Tfp pilus assembly protein FimT
KCI36_00990	COG2165	general secretion pathway protein
KCI36_00995	COG1459	type II secretion system
KCI36_01005	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KCI36_01010	COG1404	Belongs to the peptidase S8 family
KCI36_01035	COG5295	Hep Hag repeat protein
KCI36_01040	COG0047	phosphoribosylformylglycinamidine synthase activity
KCI36_01040	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KCI36_01045	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KCI36_01050	COG4974	Belongs to the 'phage' integrase family
KCI36_01060	COG0795	lipopolysaccharide-transporting ATPase activity
KCI36_01070	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KCI36_01085	COG0525	valine-tRNA ligase activity
KCI36_01140	COG3039	Transposase
KCI36_01165	COG1183	phosphatidylcholine synthase activity
KCI36_01175	COG0442	prolyl-tRNA aminoacylation
KCI36_01190	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KCI36_01195	COG1127	ABC transporter
KCI36_01200	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KCI36_01200	COG3218	ABC-type transport auxiliary lipoprotein component
KCI36_01235	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KCI36_01240	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
KCI36_01240	COG0662	Cupin 2, conserved barrel domain protein
KCI36_01265	COG2086	electron transfer activity
KCI36_01330	COG0626	cystathionine gamma-synthase activity
KCI36_01370	COG0513	Belongs to the DEAD box helicase family
KCI36_01375	COG0720	synthase
KCI36_01385	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KCI36_01390	COG1956	GAF domain-containing protein
KCI36_01425	COG0339	signal peptide processing
KCI36_01480	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KCI36_01485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KCI36_01540	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KCI36_01545	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KCI36_01550	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KCI36_01560	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KCI36_01570	COG0356	it plays a direct role in the translocation of protons across the membrane
KCI36_01590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KCI36_01600	COG0508	dehydrogenase complex catalyzes the overall conversion of
KCI36_01630	COG2011	ABC-type metal ion transport system permease component
KCI36_01640	COG0697	spore germination
KCI36_01675	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KCI36_01680	COG1187	pseudouridine synthase activity
KCI36_01685	COG2813	Specifically methylates the guanine in position
KCI36_01715	COG2202	Pas domain
KCI36_01715	COG2205	protein histidine kinase activity
KCI36_01740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KCI36_01790	COG0745	RESPONSE REGULATOR receiver
KCI36_01805	COG1404	Belongs to the peptidase S8 family
KCI36_01820	COG0842	Transport permease protein
KCI36_01825	COG1131	(ABC) transporter
KCI36_01830	COG0025	NhaP-type Na H and K H
KCI36_01840	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
KCI36_01850	COG1573	uracil-dna glycosylase
KCI36_01860	COG3384	dioxygenase
KCI36_01875	COG0667	Aldo Keto reductase
KCI36_01890	COG3590	peptidase
KCI36_01910	COG0531	amino acid
KCI36_01925	COG2972	Histidine kinase
KCI36_01950	COG2204	response regulator
KCI36_01960	COG1271	oxidase subunit
KCI36_01965	COG1294	oxidase, subunit
KCI36_02115	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KCI36_02125	COG1560	Kdo2-lipid A biosynthetic process
KCI36_02175	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KCI36_02175	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KCI36_02180	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KCI36_02185	COG0242	peptide deformylase activity
KCI36_02190	COG1652	LysM domain
KCI36_02195	COG0758	DNA mediated transformation
KCI36_02200	COG2922	Belongs to the Smg family
KCI36_02215	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KCI36_02215	COG1754	DNA topoisomerase type I activity
KCI36_02220	COG0009	L-threonylcarbamoyladenylate synthase
KCI36_02235	COG1028	Short-chain dehydrogenase reductase Sdr
KCI36_02245	COG0616	signal peptide processing
KCI36_02250	COG0534	Mate efflux family protein
KCI36_02270	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KCI36_02305	COG1324	tolerance protein
KCI36_02315	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KCI36_02320	COG0511	ligase activity, forming carbon-carbon bonds
KCI36_02330	COG0439	Biotin carboxylase
KCI36_02375	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KCI36_02395	COG2267	carboxylic ester hydrolase activity
KCI36_02400	COG2267	carboxylic ester hydrolase activity
KCI36_02415	COG0419	ATPase involved in DNA repair
KCI36_02425	COG0151	Belongs to the GarS family
KCI36_02430	COG0577	efflux transmembrane transporter activity
KCI36_02430	COG1136	(ABC) transporter
KCI36_02440	COG1289	transmembrane transporter activity
KCI36_02455	COG2814	Major facilitator Superfamily
KCI36_02470	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
KCI36_02505	COG0745	RESPONSE REGULATOR receiver
KCI36_02550	COG0739	heme binding
KCI36_02565	COG2211	Major facilitator Superfamily
KCI36_02570	COG0708	Exodeoxyribonuclease III
KCI36_02585	COG1192	Involved in chromosome partitioning
KCI36_02590	COG1475	DNA binding
KCI36_02605	COG0463	Glycosyl transferase, family 2
KCI36_02630	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KCI36_02655	COG4221	oxidoreductase activity
KCI36_02685	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KCI36_02690	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KCI36_02705	COG3485	protocatechuate 3,4-dioxygenase
KCI36_02710	COG3485	protocatechuate 3,4-dioxygenase
KCI36_02745	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KCI36_02750	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KCI36_02760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KCI36_02760	COG0045	succinate-CoA ligase (ADP-forming) activity
KCI36_02760	COG1042	CoA-binding domain protein
KCI36_02775	COG2239	Acts as a magnesium transporter
KCI36_02790	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KCI36_02800	COG3387	PFAM Glycoside hydrolase 15-related
KCI36_02815	COG3100	YcgL domain-containing protein
KCI36_02820	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KCI36_02830	COG0463	Glycosyl transferase, family 2
KCI36_02845	COG1028	Short-chain dehydrogenase reductase Sdr
KCI36_02855	COG0156	8-amino-7-oxononanoate synthase activity
KCI36_02860	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KCI36_02865	COG1040	competence protein
KCI36_02870	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KCI36_02880	COG0628	permease
KCI36_02890	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KCI36_02900	COG1595	DNA-templated transcription, initiation
KCI36_02905	COG0753	catalase activity
KCI36_02950	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KCI36_02955	COG0180	Tryptophanyl-tRNA synthetase
KCI36_02960	COG3237	CsbD-like
KCI36_02995	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KCI36_03010	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KCI36_03015	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
KCI36_03015	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
KCI36_03055	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KCI36_03075	COG1566	PFAM secretion protein HlyD family protein
KCI36_03095	COG1199	ATP-dependent helicase activity
KCI36_03135	COG0583	DNA-binding transcription factor activity
KCI36_03180	COG0625	glutathione transferase activity
KCI36_03220	COG4555	ABC transporter
KCI36_03230	COG1476	TRANSCRIPTIONal
KCI36_03255	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KCI36_03260	COG1131	(ABC) transporter
KCI36_03265	COG0842	Transport permease protein
KCI36_03275	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KCI36_03360	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KCI36_03370	COG0564	pseudouridine synthase activity
KCI36_03400	COG0339	signal peptide processing
KCI36_03430	COG3254	rhamnose metabolic process
KCI36_03435	COG0738	Major facilitator superfamily
KCI36_03440	COG1414	Transcriptional regulator
KCI36_03450	COG2205	protein histidine kinase activity
KCI36_03460	COG3459	Glycosyltransferase 36 associated
KCI36_03465	COG2211	Major facilitator Superfamily
KCI36_03470	COG3265	gluconokinase activity
KCI36_03480	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KCI36_03555	COG1127	ABC transporter
KCI36_03560	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KCI36_03565	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KCI36_03580	COG2853	Lipoprotein
KCI36_03600	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KCI36_03665	COG0676	glucose-6-phosphate 1-epimerase activity
KCI36_03695	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KCI36_03705	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KCI36_03715	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KCI36_03720	COG1064	alcohol dehydrogenase
KCI36_03765	COG1522	sequence-specific DNA binding
KCI36_03770	COG3186	Phenylalanine-4-hydroxylase
KCI36_03810	COG2937	Belongs to the GPAT DAPAT family
KCI36_03845	COG0284	orotidine-5'-phosphate decarboxylase activity
KCI36_03850	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
KCI36_03855	COG3132	Protein of unknown function, DUF480
KCI36_03870	COG0210	DNA helicase
KCI36_03885	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
KCI36_03910	COG1028	Short-chain dehydrogenase reductase Sdr
KCI36_03935	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KCI36_03995	COG1166	arginine decarboxylase activity
KCI36_04000	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KCI36_04040	COG0606	chelatase, subunit chli
KCI36_04085	COG0366	Alpha amylase catalytic
KCI36_04090	COG0366	Alpha amylase catalytic
KCI36_04115	COG1609	Transcriptional regulator
KCI36_04165	COG0493	'glutamate synthase
KCI36_04170	COG0070	glutamate synthase
KCI36_04170	COG0069	glutamate synthase activity
KCI36_04170	COG0067	glutamate synthase
KCI36_04230	COG1205	dead DEAH box helicase
KCI36_04230	COG1111	helicase
KCI36_04235	COG1272	protein, Hemolysin III
KCI36_04275	COG1136	(ABC) transporter
KCI36_04340	COG2826	transposase and inactivated derivatives, IS30 family
KCI36_04365	COG3039	Transposase
KCI36_04375	COG1090	epimerase
KCI36_04385	COG0642	Histidine kinase
KCI36_04395	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KCI36_04435	COG3039	Transposase
KCI36_04445	COG3039	Transposase
KCI36_04520	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KCI36_04595	COG1511	domain protein
KCI36_04595	COG3264	Mechanosensitive ion channel
KCI36_04610	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KCI36_04615	COG2354	Protein conserved in bacteria
KCI36_04620	COG1649	PFAM Uncharacterised BCR, COG1649
KCI36_04640	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KCI36_04665	COG0702	epimerase
KCI36_04680	COG1858	cytochrome C peroxidase
KCI36_04760	COG0513	Belongs to the DEAD box helicase family
KCI36_04765	COG3039	Transposase
KCI36_04810	COG1136	(ABC) transporter
KCI36_04820	COG3039	Transposase
KCI36_04830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KCI36_04855	COG1755	Isoprenylcysteine carboxyl methyltransferase
KCI36_04860	COG1304	FMN binding
KCI36_04865	COG3039	Transposase
KCI36_04880	COG4772	TonB-dependent receptor
KCI36_04890	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
KCI36_04900	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KCI36_04940	COG0501	Belongs to the peptidase M48B family
KCI36_04950	COG0187	DNA topoisomerase II activity
KCI36_04965	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KCI36_04985	COG0726	polysaccharide deacetylase
KCI36_04995	COG0671	phosphoesterase, PA-phosphatase related
KCI36_05005	COG0584	glycerophosphoryl diester phosphodiesterase
KCI36_05015	COG0861	Integral membrane protein TerC family
KCI36_05020	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KCI36_05035	COG2271	Major facilitator Superfamily
KCI36_05040	COG1929	Belongs to the glycerate kinase type-1 family
KCI36_05130	COG0477	Major facilitator Superfamily
KCI36_05155	COG0302	gtp cyclohydrolase
KCI36_05160	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KCI36_05205	COG2234	aminopeptidase activity
KCI36_05215	COG4942	peptidase
KCI36_05220	COG0793	Belongs to the peptidase S41A family
KCI36_05270	COG0386	Belongs to the glutathione peroxidase family
KCI36_05280	COG1322	Protein conserved in bacteria
KCI36_05290	COG0531	amino acid
KCI36_05305	COG0210	DNA helicase
KCI36_05320	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KCI36_05325	COG0583	DNA-binding transcription factor activity
KCI36_05330	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KCI36_05350	COG2159	amidohydrolase
KCI36_05380	COG3540	Alkaline phosphatase
KCI36_05390	COG2091	lysine biosynthetic process via aminoadipic acid
KCI36_05405	COG0708	Exodeoxyribonuclease III
KCI36_05420	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KCI36_05425	COG3162	membrane
KCI36_05465	COG3507	Belongs to the glycosyl hydrolase 43 family
KCI36_05485	COG1028	Short-chain dehydrogenase reductase Sdr
KCI36_05490	COG0179	Fumarylacetoacetate (FAA) hydrolase
KCI36_05495	COG4948	Mandelate Racemase Muconate Lactonizing
KCI36_05500	COG4807	Protein conserved in bacteria
KCI36_05505	COG1643	Atp-dependent helicase
KCI36_05520	COG1187	pseudouridine synthase activity
KCI36_05530	COG0667	Aldo Keto reductase
KCI36_05535	COG2130	NADP-dependent
KCI36_05540	COG0656	L-ascorbic acid biosynthetic process
KCI36_05580	COG1752	Esterase of the alpha-beta hydrolase superfamily
KCI36_05590	COG1119	ATPase activity
KCI36_05605	COG0517	IMP dehydrogenase activity
KCI36_05605	COG1125	glycine betaine transport
KCI36_05620	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KCI36_05625	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
KCI36_05630	COG3550	peptidyl-serine autophosphorylation
KCI36_05635	COG1396	sequence-specific DNA binding
KCI36_05655	COG0489	protein tyrosine kinase activity
KCI36_05660	COG2062	phosphohistidine phosphatase, SixA
KCI36_05670	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KCI36_05715	COG1968	undecaprenyl-diphosphatase activity
KCI36_05720	COG0174	glutamine synthetase
KCI36_05725	COG0347	Belongs to the P(II) protein family
KCI36_05730	COG0004	ammonium transporteR
KCI36_05735	COG3852	Histidine kinase
KCI36_05740	COG2204	response regulator
KCI36_05745	COG2032	superoxide dismutase activity
KCI36_05750	COG2032	superoxide dismutase activity
KCI36_05795	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KCI36_05800	COG1074	ATP-dependent DNA helicase activity
KCI36_05810	COG3549	Plasmid maintenance system killer
KCI36_05890	COG1764	response to oxidative stress
KCI36_05895	COG1846	Transcriptional regulator
KCI36_05985	COG2211	Major facilitator Superfamily
KCI36_06005	COG3693	PFAM glycoside hydrolase, family 10
KCI36_06030	COG0246	Mannitol dehydrogenase
KCI36_06035	COG1472	Belongs to the glycosyl hydrolase 3 family
KCI36_06045	COG4948	Mandelate Racemase Muconate Lactonizing
KCI36_06055	COG3661	Belongs to the glycosyl hydrolase 67 family
KCI36_06100	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KCI36_06110	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KCI36_06120	COG0805	protein transport
KCI36_06130	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KCI36_06130	COG0519	Catalyzes the synthesis of GMP from XMP
KCI36_06145	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KCI36_06160	COG0457	Tetratricopeptide repeat
KCI36_06165	COG4771	TonB-dependent receptor
KCI36_06180	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KCI36_06200	COG0523	cobalamin synthesis protein
KCI36_06255	COG1960	acyl-CoA dehydrogenase activity
KCI36_06260	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KCI36_06265	COG4770	biotin carboxylase activity
KCI36_06315	COG2072	flavoprotein involved in K transport
KCI36_06335	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KCI36_06385	COG0084	hydrolase, TatD family'
KCI36_06400	COG0583	DNA-binding transcription factor activity
KCI36_06405	COG2814	Major facilitator Superfamily
KCI36_06415	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KCI36_06420	COG1902	pentaerythritol trinitrate reductase activity
KCI36_06450	COG0745	RESPONSE REGULATOR receiver
KCI36_06470	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KCI36_06475	COG0583	DNA-binding transcription factor activity
KCI36_06505	COG0702	epimerase
KCI36_06510	COG1733	regulation of RNA biosynthetic process
KCI36_06565	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KCI36_06580	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KCI36_06615	COG2911	Protein conserved in bacteria
KCI36_06620	COG0729	surface antigen
KCI36_06635	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KCI36_06640	COG3118	belongs to the thioredoxin family
KCI36_06650	COG2884	Cell division ATP-binding protein ftsE
KCI36_06655	COG2177	Part of the ABC transporter FtsEX involved in
KCI36_06660	COG2201	protein-glutamate methylesterase activity
KCI36_06665	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KCI36_06670	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KCI36_06680	COG1252	NADH dehydrogenase
KCI36_06705	COG0459	protein refolding
KCI36_06715	COG4771	TonB-dependent receptor
KCI36_06730	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KCI36_06770	COG3386	PFAM SMP-30 Gluconolaconase
KCI36_06785	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KCI36_06815	COG2353	YceI-like domain
KCI36_06860	COG2201	protein-glutamate methylesterase activity
KCI36_06905	COG0408	coproporphyrinogen oxidase activity
KCI36_06915	COG3039	Transposase
KCI36_06935	COG0129	dihydroxy-acid dehydratase activity
KCI36_06945	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KCI36_06995	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KCI36_07000	COG0318	PFAM AMP-dependent synthetase and ligase
KCI36_07005	COG0727	PFAM Uncharacterised protein family (UPF0153)
KCI36_07010	COG0596	Alpha beta hydrolase
KCI36_07025	COG3177	Filamentation induced by cAMP protein fic
KCI36_07030	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KCI36_07045	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KCI36_07070	COG4191	Histidine kinase
KCI36_07075	COG0028	Belongs to the TPP enzyme family
KCI36_07090	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
KCI36_07095	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KCI36_07130	COG5383	Protein conserved in bacteria
KCI36_07140	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KCI36_07145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KCI36_07150	COG1473	amidohydrolase
KCI36_07160	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KCI36_07160	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KCI36_07165	COG3328	transposase activity
KCI36_07175	COG3039	Transposase
KCI36_07245	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KCI36_07260	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KCI36_07265	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KCI36_07275	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
KCI36_07280	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KCI36_07285	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KCI36_07335	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KCI36_07350	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
KCI36_07415	COG0358	DNA primase activity
KCI36_07420	COG1295	ribonuclease BN
KCI36_07430	COG1610	YqeY-like protein
KCI36_07440	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KCI36_07445	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KCI36_07480	COG2133	pyrroloquinoline quinone binding
KCI36_07485	COG4682	membrane
KCI36_07520	COG0531	amino acid
KCI36_07555	COG4948	Mandelate Racemase Muconate Lactonizing
KCI36_07565	COG3023	N-Acetylmuramoyl-L-alanine amidase
KCI36_07570	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
KCI36_07600	COG3039	Transposase
KCI36_07650	COG0183	Belongs to the thiolase family
KCI36_07685	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KCI36_07695	COG3483	tryptophan 2,3-dioxygenase activity
KCI36_07700	COG3104	oligopeptide transport
KCI36_07720	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
KCI36_07730	COG1320	monovalent cation:proton antiporter activity
KCI36_07735	COG2212	antiporter activity
KCI36_07745	COG0651	ATP synthesis coupled electron transport
KCI36_07750	COG1006	Multisubunit Na H antiporter MnhC subunit
KCI36_07755	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KCI36_07755	COG2111	Na H antiporter
KCI36_07800	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KCI36_07810	COG0456	acetyltransferase
KCI36_07840	COG4221	oxidoreductase activity
KCI36_07900	COG0697	spore germination
KCI36_07905	COG4305	rare lipoprotein A
KCI36_07910	COG5297	Belongs to the glycosyl hydrolase family 6
KCI36_07920	COG1113	amino acid transport
KCI36_07930	COG0598	Magnesium transport protein CorA
KCI36_08000	COG5297	Belongs to the glycosyl hydrolase family 6
KCI36_08000	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KCI36_08005	COG0659	secondary active sulfate transmembrane transporter activity
KCI36_08040	COG3275	phosphorelay sensor kinase activity
KCI36_08050	COG0181	hydroxymethylbilane synthase activity
KCI36_08075	COG1505	serine-type exopeptidase activity
KCI36_08090	COG0436	Aminotransferase
KCI36_08120	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KCI36_08150	COG0308	aminopeptidase N
KCI36_08155	COG2199	diguanylate cyclase activity
KCI36_08200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KCI36_08205	COG1077	Cell shape determining protein MreB Mrl
KCI36_08210	COG1792	Involved in formation and maintenance of cell shape
KCI36_08225	COG0772	Belongs to the SEDS family
KCI36_08260	COG1388	LysM domain
KCI36_08260	COG3409	Peptidoglycan-binding domain 1 protein
KCI36_08260	COG5632	N-Acetylmuramoyl-L-alanine amidase
KCI36_08280	COG2951	lytic endotransglycosylase activity
KCI36_08285	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KCI36_08290	COG1686	Belongs to the peptidase S11 family
KCI36_08305	COG2921	Belongs to the UPF0250 family
KCI36_08345	COG1051	belongs to the nudix hydrolase family
KCI36_08345	COG1056	cytidyltransferase-related domain
KCI36_08380	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KCI36_08385	COG0673	inositol 2-dehydrogenase activity
KCI36_08390	COG2823	Periplasmic or secreted lipoprotein
KCI36_08395	COG4251	negative regulation of phosphorylation
KCI36_08400	COG0784	Response regulator, receiver
KCI36_08405	COG4191	Histidine kinase
KCI36_08410	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KCI36_08460	COG3250	beta-galactosidase activity
KCI36_08475	COG2188	Transcriptional regulator
KCI36_08485	COG1609	Transcriptional regulator
KCI36_08490	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KCI36_08495	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KCI36_08505	COG1215	transferase activity, transferring glycosyl groups
KCI36_08510	COG1649	PFAM Uncharacterised BCR, COG1649
KCI36_08510	COG0726	polysaccharide deacetylase
KCI36_08540	COG3293	Transposase
KCI36_08550	COG3039	Transposase
KCI36_08610	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KCI36_08615	COG3039	Transposase
KCI36_08650	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KCI36_08670	COG2205	protein histidine kinase activity
KCI36_08710	COG2205	protein histidine kinase activity
KCI36_08760	COG0488	(ABC) transporter
KCI36_08780	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KCI36_08800	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KCI36_08800	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KCI36_08820	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KCI36_08825	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KCI36_08830	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KCI36_08850	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KCI36_08855	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
KCI36_08865	COG2205	protein histidine kinase activity
KCI36_08870	COG0745	RESPONSE REGULATOR receiver
KCI36_08875	COG0277	FAD linked oxidase domain protein
KCI36_08880	COG1988	membrane-bound metal-dependent
KCI36_08885	COG0792	nuclease activity
KCI36_08920	COG0275	rRNA processing
KCI36_08925	COG3116	cell division
KCI36_08940	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KCI36_08945	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KCI36_08960	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KCI36_08965	COG1181	Belongs to the D-alanine--D-alanine ligase family
KCI36_08970	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KCI36_08985	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
KCI36_08995	COG1388	LysM domain
KCI36_08995	COG4942	peptidase
KCI36_09010	COG0494	nUDIX hydrolase
KCI36_09025	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KCI36_09035	COG1028	Short-chain dehydrogenase reductase Sdr
KCI36_09035	COG3321	synthase
KCI36_09035	COG0604	alcohol dehydrogenase
KCI36_09080	COG2226	methyltransferase
KCI36_09085	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KCI36_09130	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KCI36_09145	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KCI36_09155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KCI36_09160	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KCI36_09170	COG0667	Aldo Keto reductase
KCI36_09210	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
KCI36_09220	COG2175	clavaminate synthase activity
KCI36_09230	COG4181	ATPase activity
KCI36_09245	COG0642	Histidine kinase
KCI36_09270	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KCI36_09290	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KCI36_09315	COG2967	ApaG domain
KCI36_09320	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KCI36_09330	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KCI36_09345	COG0123	including yeast histone deacetylase and acetoin utilization protein
KCI36_09350	COG2096	Adenosyltransferase
KCI36_09360	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KCI36_09365	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KCI36_09405	COG0583	DNA-binding transcription factor activity
KCI36_09410	COG0318	PFAM AMP-dependent synthetase and ligase
KCI36_09420	COG1024	Enoyl-CoA hydratase
KCI36_09440	COG3386	PFAM SMP-30 Gluconolaconase
KCI36_09565	COG1902	pentaerythritol trinitrate reductase activity
KCI36_09565	COG0446	pyridine nucleotide-disulphide oxidoreductase
KCI36_09570	COG0604	alcohol dehydrogenase
KCI36_09595	COG0156	8-amino-7-oxononanoate synthase activity
KCI36_09600	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KCI36_09605	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KCI36_09610	COG4208	sulfate ABC transporter
KCI36_09615	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KCI36_09645	COG0406	alpha-ribazole phosphatase activity
KCI36_09655	COG0285	dihydrofolate synthase activity
KCI36_09675	COG2833	Protein of unknown function (DUF455)
KCI36_09695	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KCI36_09700	COG0671	phosphoesterase, PA-phosphatase related
KCI36_09705	COG0438	transferase activity, transferring glycosyl groups
KCI36_09715	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KCI36_09730	COG4783	chaperone-mediated protein folding
KCI36_09795	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KCI36_09800	COG0583	DNA-binding transcription factor activity
KCI36_09805	COG3634	alkyl hydroperoxide reductase activity
KCI36_09815	COG2890	protein-(glutamine-N5) methyltransferase activity
KCI36_09865	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KCI36_09865	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KCI36_09880	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
KCI36_09905	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
KCI36_09930	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KCI36_09940	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KCI36_09970	COG1295	ribonuclease BN
KCI36_09975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KCI36_09995	COG0521	Mo-molybdopterin cofactor biosynthetic process
KCI36_10005	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KCI36_10020	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
KCI36_10035	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KCI36_10045	COG0193	aminoacyl-tRNA hydrolase activity
KCI36_10050	COG0012	GTP binding
KCI36_10080	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KCI36_10085	COG0250	Participates in transcription elongation, termination and antitermination
KCI36_10090	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KCI36_10100	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KCI36_10105	COG0222	ribosome binding
KCI36_10110	COG0085	RNA polymerase activity
KCI36_10115	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KCI36_10120	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KCI36_10125	COG0049	tRNA binding
KCI36_10145	COG0051	transcription antitermination factor activity, RNA binding
KCI36_10150	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KCI36_10155	COG0088	Forms part of the polypeptide exit tunnel
KCI36_10160	COG0089	rRNA binding
KCI36_10175	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KCI36_10185	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KCI36_10190	COG0255	Belongs to the universal ribosomal protein uL29 family
KCI36_10195	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KCI36_10200	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KCI36_10210	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KCI36_10240	COG1841	ribosomal large subunit assembly
KCI36_10250	COG0201	protein transport
KCI36_10260	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KCI36_10265	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KCI36_10275	COG0203	ribosomal protein L17
KCI36_10335	COG3551	Protein conserved in bacteria
KCI36_10365	COG2194	sulfuric ester hydrolase activity
KCI36_10375	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KCI36_10380	COG0745	RESPONSE REGULATOR receiver
KCI36_10385	COG0642	Histidine kinase
KCI36_10395	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
KCI36_10400	COG2894	cell division
KCI36_10415	COG4585	Histidine kinase
KCI36_10420	COG2197	response regulator
KCI36_10435	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KCI36_10575	COG3039	Transposase
KCI36_10775	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
KCI36_10795	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
KCI36_10800	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
KCI36_10810	COG3039	Transposase
KCI36_10815	COG0732	type I restriction modification DNA specificity domain
KCI36_10835	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KCI36_10870	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KCI36_10875	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KCI36_10930	COG1297	OPT oligopeptide transporter protein
KCI36_10935	COG3039	Transposase
KCI36_10955	COG1506	peptidase
KCI36_10955	COG0823	Involved in the tonB-independent uptake of proteins
KCI36_10985	COG1917	Cupin 2, conserved barrel domain protein
KCI36_10985	COG2207	Transcriptional regulator
KCI36_11025	COG0753	catalase activity
KCI36_11065	COG0469	pyruvate kinase activity
KCI36_11070	COG3588	fructose-bisphosphate aldolase
KCI36_11075	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
KCI36_11125	COG0784	Response regulator, receiver
KCI36_11125	COG2198	Histidine kinase
KCI36_11125	COG2205	protein histidine kinase activity
KCI36_11145	COG0175	sulfate reduction
KCI36_11150	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KCI36_11155	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KCI36_11160	COG0175	sulfate reduction
KCI36_11165	COG0529	Catalyzes the synthesis of activated sulfate
KCI36_11165	COG2895	sulfate adenylyltransferase (ATP) activity
KCI36_11175	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KCI36_11180	COG0308	aminopeptidase N
KCI36_11200	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KCI36_11230	COG1970	mechanosensitive ion channel activity
KCI36_11260	COG3273	potassium ion transport
KCI36_11260	COG0471	metal ion transport
KCI36_11270	COG2022	thiamine diphosphate biosynthetic process
KCI36_11350	COG3039	Transposase
KCI36_11420	COG3118	belongs to the thioredoxin family
KCI36_11445	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KCI36_11470	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KCI36_11495	COG2968	Membrane
KCI36_11510	COG3164	Protein of unknown function
KCI36_11520	COG0312	modulator of DNA gyrase
KCI36_11525	COG3028	Belongs to the UPF0307 family
KCI36_11530	COG0312	modulator of DNA gyrase
KCI36_11555	COG0142	geranyltranstransferase activity
KCI36_11560	COG1722	exodeoxyribonuclease VII activity
KCI36_11565	COG0037	tRNA processing
KCI36_11570	COG1785	Belongs to the alkaline phosphatase family
KCI36_11575	COG1301	dicarboxylic acid transport
KCI36_11595	COG0791	NLP P60 protein
KCI36_11600	COG0791	NLP P60 protein
KCI36_11605	COG1047	Peptidyl-prolyl cis-trans
KCI36_11610	COG2311	Membrane
KCI36_11615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KCI36_11655	COG0489	protein tyrosine kinase activity
KCI36_11660	COG0717	Belongs to the dCTP deaminase family
KCI36_11680	COG0412	Dienelactone hydrolase
KCI36_11690	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KCI36_11730	COG2890	protein-(glutamine-N5) methyltransferase activity
KCI36_11735	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KCI36_11740	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KCI36_11745	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KCI36_11765	COG0101	tRNA pseudouridine synthase activity
KCI36_11770	COG0135	phosphoribosylanthranilate isomerase activity
KCI36_11795	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KCI36_11800	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KCI36_11850	COG0149	triose-phosphate isomerase activity
KCI36_11865	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KCI36_11875	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KCI36_11880	COG0649	NAD binding
KCI36_11885	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
KCI36_11890	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KCI36_11895	COG1034	ATP synthesis coupled electron transport
KCI36_11930	COG1007	ATP synthesis coupled electron transport
KCI36_11940	COG0779	Required for maturation of 30S ribosomal subunits
KCI36_11945	COG0195	Participates in both transcription termination and antitermination
KCI36_11965	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KCI36_11970	COG1185	polyribonucleotide nucleotidyltransferase activity
KCI36_12005	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KCI36_12015	COG2095	MarC family integral membrane protein
KCI36_12030	COG1611	Belongs to the LOG family
KCI36_12070	COG4969	Belongs to the N-Me-Phe pilin family
KCI36_12110	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KCI36_12180	COG0438	transferase activity, transferring glycosyl groups
KCI36_12185	COG0438	transferase activity, transferring glycosyl groups
KCI36_12195	COG0438	transferase activity, transferring glycosyl groups
KCI36_12235	COG3040	lipid binding
KCI36_12320	COG4191	Histidine kinase
KCI36_12320	COG0784	Response regulator, receiver
KCI36_12340	COG0552	protein localization to endoplasmic reticulum
KCI36_12350	COG3938	Belongs to the proline racemase family
KCI36_12355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KCI36_12370	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KCI36_12380	COG0006	proline dipeptidase activity
KCI36_12395	COG0531	amino acid
KCI36_12445	COG4206	TonB-dependent receptor
KCI36_12470	COG4206	TonB-dependent receptor
KCI36_12475	COG3328	transposase activity
KCI36_12540	COG0746	molybdenum cofactor guanylyltransferase activity
KCI36_12565	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KCI36_12565	COG1648	precorrin-2 dehydrogenase activity
KCI36_12610	COG3039	Transposase
KCI36_12645	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KCI36_12670	COG1054	Belongs to the UPF0176 family
KCI36_12685	COG1530	ribonuclease E activity
KCI36_12695	COG3064	Membrane
KCI36_12700	COG0428	transporter
KCI36_12705	COG0428	transporter
KCI36_12715	COG2154	pterin-4-alpha-carbinolamine dehydratase
KCI36_12720	COG0316	Belongs to the HesB IscA family
KCI36_12720	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KCI36_12780	COG3039	Transposase
KCI36_12890	COG0631	protein serine/threonine phosphatase activity
KCI36_12895	COG0515	serine threonine protein kinase
KCI36_12930	COG1858	cytochrome C peroxidase
KCI36_12980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KCI36_12985	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KCI36_13050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KCI36_13070	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KCI36_13085	COG1595	DNA-templated transcription, initiation
KCI36_13135	COG2244	polysaccharide biosynthetic process
KCI36_13165	COG2264	protein methyltransferase activity
KCI36_13175	COG0438	transferase activity, transferring glycosyl groups
KCI36_13195	COG1136	(ABC) transporter
KCI36_13200	COG1132	(ABC) transporter
KCI36_13210	COG0477	Major facilitator Superfamily
KCI36_13220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCI36_13235	COG1253	flavin adenine dinucleotide binding
KCI36_13245	COG0306	phosphate transporter
KCI36_13250	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KCI36_13275	COG0504	CTP synthase activity
KCI36_13280	COG2877	3-deoxy-8-phosphooctulonate synthase activity
KCI36_13290	COG0148	phosphopyruvate hydratase activity
KCI36_13295	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KCI36_13310	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KCI36_13320	COG2840	Smr protein MutS2
KCI36_13325	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KCI36_13330	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KCI36_13335	COG1238	metal cluster binding
KCI36_13350	COG1534	Rna-binding protein
KCI36_13355	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KCI36_13365	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KCI36_13380	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KCI36_13385	COG1546	Belongs to the CinA family
KCI36_13400	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KCI36_13405	COG2137	regulation of response to DNA damage stimulus
KCI36_13410	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KCI36_13415	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KCI36_13435	COG0305	Participates in initiation and elongation during chromosome replication
KCI36_13440	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KCI36_13460	COG1741	Belongs to the pirin family
KCI36_13465	COG0583	DNA-binding transcription factor activity
KCI36_13495	COG0351	phosphomethylpyrimidine kinase
KCI36_13505	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KCI36_13510	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KCI36_13525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KCI36_13535	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KCI36_13540	COG3734	2-keto-3-deoxy-galactonokinase
KCI36_13550	COG4948	Mandelate Racemase Muconate Lactonizing
KCI36_13555	COG0800	Aldolase
KCI36_13570	COG1501	Belongs to the glycosyl hydrolase 31 family
KCI36_13580	COG1070	Carbohydrate kinase
KCI36_13590	COG0477	Major facilitator Superfamily
KCI36_13610	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KCI36_13660	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KCI36_13665	COG2258	MOSC domain
KCI36_13675	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KCI36_13680	COG0505	Belongs to the CarA family
KCI36_13690	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KCI36_13695	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KCI36_13705	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KCI36_13765	COG0784	Response regulator, receiver
KCI36_13765	COG2198	Histidine kinase
KCI36_13765	COG2205	protein histidine kinase activity
KCI36_13770	COG1024	Enoyl-CoA hydratase
KCI36_13775	COG0318	PFAM AMP-dependent synthetase and ligase
KCI36_13805	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KCI36_13835	COG0840	transmembrane signaling receptor activity
KCI36_13855	COG0835	chemotaxis
KCI36_13870	COG0840	transmembrane signaling receptor activity
KCI36_13875	COG0840	transmembrane signaling receptor activity
KCI36_13880	COG0840	transmembrane signaling receptor activity
KCI36_13885	COG0840	transmembrane signaling receptor activity
KCI36_13895	COG0840	transmembrane signaling receptor activity
KCI36_13905	COG0840	transmembrane signaling receptor activity
KCI36_13915	COG0840	transmembrane signaling receptor activity
KCI36_13935	COG0745	RESPONSE REGULATOR receiver
KCI36_13945	COG0835	chemotaxis
KCI36_13955	COG1360	Flagellar Motor Protein
KCI36_13960	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KCI36_13980	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KCI36_13990	COG4771	TonB-dependent receptor
KCI36_14020	COG3039	Transposase
KCI36_14150	COG3039	Transposase
KCI36_14165	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KCI36_14165	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KCI36_14170	COG1105	Belongs to the carbohydrate kinase PfkB family
KCI36_14175	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KCI36_14175	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KCI36_14180	COG1609	Transcriptional regulator
KCI36_14200	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KCI36_14205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KCI36_14215	COG2902	Dehydrogenase
KCI36_14220	COG3039	Transposase
KCI36_14230	COG2205	protein histidine kinase activity
KCI36_14230	COG5002	protein histidine kinase activity
KCI36_14230	COG0784	Response regulator, receiver
KCI36_14235	COG2733	membrane
KCI36_14245	COG1121	(ABC) transporter
KCI36_14250	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KCI36_14260	COG2223	nitrite transmembrane transporter activity
KCI36_14270	COG0243	molybdopterin cofactor binding
KCI36_14280	COG0477	Major facilitator Superfamily
KCI36_14290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KCI36_14295	COG0174	glutamine synthetase
KCI36_14330	COG3842	ATPase activity
KCI36_14340	COG1177	transmembrane transport
KCI36_14350	COG1012	belongs to the aldehyde dehydrogenase family
KCI36_14365	COG4535	Mg2 and Co2 transporter CorC
KCI36_14385	COG1702	phosphate starvation-inducible protein PhoH
KCI36_14410	COG0741	lytic transglycosylase activity
KCI36_14415	COG0723	plastoquinol--plastocyanin reductase activity
KCI36_14420	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KCI36_14425	COG2857	Cytochrome c1
KCI36_14430	COG0625	glutathione transferase activity
KCI36_14435	COG2969	positive regulation of protein catabolic process
KCI36_14545	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KCI36_14570	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KCI36_14575	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KCI36_14575	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KCI36_14580	COG0802	atpase or kinase
KCI36_14585	COG0860	N-Acetylmuramoyl-L-alanine amidase
KCI36_14590	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KCI36_14610	COG1028	Short-chain dehydrogenase reductase Sdr
KCI36_14630	COG2081	HI0933 family
KCI36_14635	COG4681	YaeQ
KCI36_14640	COG1671	Belongs to the UPF0178 family
KCI36_14650	COG0625	glutathione transferase activity
KCI36_14670	COG0513	Belongs to the DEAD box helicase family
KCI36_14675	COG0488	(ABC) transporter
KCI36_14695	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KCI36_14700	COG0483	inositol monophosphate 1-phosphatase activity
KCI36_14715	COG5001	Diguanylate cyclase
KCI36_14715	COG3300	MHYT domain
KCI36_14720	COG1509	lysine 2,3-aminomutase activity
KCI36_14735	COG0402	S-adenosylhomocysteine deaminase activity
KCI36_14740	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KCI36_14765	COG4677	pectinesterase activity
KCI36_14775	COG3039	Transposase
KCI36_14810	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KCI36_14835	COG2166	iron-sulfur cluster assembly
KCI36_14850	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KCI36_14855	COG0137	argininosuccinate synthase activity
KCI36_14865	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KCI36_14870	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KCI36_14885	COG0165	Argininosuccinate lyase
KCI36_14905	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KCI36_14940	COG1271	oxidase subunit
KCI36_14960	COG4988	ABC transporter
KCI36_14965	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KCI36_15050	COG3039	Transposase
KCI36_15080	COG0643	Histidine kinase
KCI36_15080	COG0784	Response regulator, receiver
KCI36_15080	COG2198	Histidine kinase
KCI36_15135	COG1684	flagellar biosynthetic protein fliR
KCI36_15150	COG3190	flagellar
KCI36_15200	COG1677	Flagellar hook-basal body complex protein FliE
KCI36_15230	COG1028	Short-chain dehydrogenase reductase Sdr
KCI36_15240	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KCI36_15260	COG2201	protein-glutamate methylesterase activity
KCI36_15295	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KCI36_15300	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KCI36_15335	COG4787	bacterial-type flagellum-dependent cell motility
KCI36_15345	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
KCI36_15350	COG1558	bacterial-type flagellum-dependent cell motility
KCI36_15360	COG0784	Response regulator, receiver
KCI36_15360	COG0835	chemotaxis
KCI36_15380	COG5002	protein histidine kinase activity
KCI36_15390	COG4585	Histidine kinase
KCI36_15395	COG5001	Diguanylate cyclase
KCI36_15420	COG0482	sulfurtransferase activity
KCI36_15435	COG0542	response to heat
KCI36_15460	COG0492	ferredoxin-NADP+ reductase activity
KCI36_15465	COG1674	ftsk spoiiie
KCI36_15485	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KCI36_15505	COG0038	chloride channel
KCI36_15510	COG0183	Belongs to the thiolase family
KCI36_15515	COG1250	3-hydroxyacyl-CoA dehydrogenase
KCI36_15515	COG1024	Enoyl-CoA hydratase
KCI36_15530	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KCI36_15540	COG1426	Protein conserved in bacteria
KCI36_15550	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KCI36_15560	COG0303	'Molybdopterin
KCI36_15590	COG3039	Transposase
KCI36_15600	COG3039	Transposase
KCI36_15630	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KCI36_15650	COG0742	ribosomal rna small subunit methyltransferase
KCI36_15655	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KCI36_15665	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KCI36_15670	COG0405	Gamma-glutamyltransferase
KCI36_15745	COG0343	queuine tRNA-ribosyltransferase activity
KCI36_15750	COG1862	Preprotein translocase
KCI36_15755	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KCI36_15760	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KCI36_15790	COG3328	transposase activity
KCI36_15805	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KCI36_15815	COG0704	Plays a role in the regulation of phosphate uptake
KCI36_15830	COG0573	inorganic phosphate transmembrane transporter activity
KCI36_15835	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KCI36_15875	COG3039	Transposase
KCI36_15890	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KCI36_15900	COG1024	Enoyl-CoA hydratase
KCI36_15910	COG0494	nUDIX hydrolase
KCI36_15955	COG0116	Belongs to the methyltransferase superfamily
KCI36_15955	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KCI36_15980	COG0667	Aldo Keto reductase
KCI36_15990	COG2925	Exonuclease
KCI36_16020	COG0288	reversible hydration of carbon dioxide
KCI36_16050	COG0316	Belongs to the HesB IscA family
KCI36_16055	COG0360	Binds together with S18 to 16S ribosomal RNA
KCI36_16065	COG0359	binds to the 23S rRNA
KCI36_16075	COG3115	cell septum assembly
KCI36_16090	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
KCI36_16105	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KCI36_16130	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KCI36_16140	COG2986	histidine ammonia-lyase
KCI36_16145	COG1228	amidohydrolase
KCI36_16185	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KCI36_16195	COG0077	Prephenate dehydratase
KCI36_16195	COG1605	Chorismate mutase
KCI36_16200	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KCI36_16240	COG4566	intracellular signal transduction
KCI36_16285	COG0860	N-Acetylmuramoyl-L-alanine amidase
KCI36_16290	COG1469	GTP cyclohydrolase I activity
KCI36_16300	COG0617	tRNA 3'-terminal CCA addition
KCI36_16345	COG1472	Belongs to the glycosyl hydrolase 3 family
KCI36_16360	COG2203	Gaf domain
KCI36_16360	COG3706	GGDEF domain
KCI36_16360	COG4251	negative regulation of phosphorylation
KCI36_16360	COG5001	Diguanylate cyclase
KCI36_16445	COG0386	Belongs to the glutathione peroxidase family
KCI36_16525	COG5002	protein histidine kinase activity
KCI36_16525	COG0784	Response regulator, receiver
KCI36_16525	COG2205	protein histidine kinase activity
KCI36_16555	COG0800	Aldolase
KCI36_16560	COG0129	dihydroxy-acid dehydratase activity
KCI36_16565	COG0363	glucosamine-6-phosphate deaminase activity
KCI36_16575	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KCI36_16590	COG0354	folic acid binding
KCI36_16605	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KCI36_16620	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KCI36_16635	COG4591	ABC-type transport system involved in lipoprotein release permease component
KCI36_16660	COG0811	peptide transport
KCI36_16675	COG1663	tetraacyldisaccharide 4'-kinase activity
KCI36_16685	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KCI36_16695	COG0322	excinuclease ABC activity
KCI36_16765	COG2801	Transposase and inactivated derivatives
KCI36_16965	COG0653	protein targeting
KCI36_17005	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KCI36_17005	COG0140	phosphoribosyl-ATP diphosphatase activity
KCI36_17015	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KCI36_17025	COG0131	Imidazoleglycerol-phosphate dehydratase
KCI36_17025	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KCI36_17040	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KCI36_17060	COG0124	histidyl-tRNA synthetase
KCI36_17075	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KCI36_17110	COG1012	belongs to the aldehyde dehydrogenase family
KCI36_17135	COG0697	spore germination
KCI36_17140	COG1794	racemase activity, acting on amino acids and derivatives
KCI36_17160	COG0671	phosphoesterase, PA-phosphatase related
KCI36_17175	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
KCI36_17190	COG2183	response to ionizing radiation
KCI36_17200	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KCI36_17200	COG0723	plastoquinol--plastocyanin reductase activity
KCI36_17215	COG3243	poly(R)-hydroxyalkanoic acid synthase
KCI36_17225	COG1183	phosphatidylcholine synthase activity
KCI36_17230	COG1028	Short-chain dehydrogenase reductase Sdr
KCI36_17285	COG0668	transmembrane transport
KCI36_17305	COG1914	H( )-stimulated, divalent metal cation uptake system
KCI36_17325	COG0583	DNA-binding transcription factor activity
KCI36_17355	COG0583	DNA-binding transcription factor activity
KCI36_17360	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KCI36_17365	COG3002	Belongs to the UPF0753 family
KCI36_17380	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KCI36_17400	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KCI36_17410	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KCI36_17415	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
KCI36_17425	COG0776	regulation of translation
KCI36_17430	COG0539	negative regulation of cytoplasmic translation
KCI36_17435	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KCI36_17450	COG2957	Belongs to the agmatine deiminase family
KCI36_17460	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KCI36_17485	COG0395	ABC-type sugar transport system, permease component
KCI36_17490	COG1175	transmembrane transport
KCI36_17520	COG2350	Protein conserved in bacteria
KCI36_17525	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KCI36_17530	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KCI36_17535	COG1187	pseudouridine synthase activity
KCI36_17560	COG0436	Aminotransferase
KCI36_17625	COG0277	FAD linked oxidase domain protein
KCI36_17630	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KCI36_17640	COG0531	amino acid
KCI36_17645	COG0531	amino acid
KCI36_17655	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KCI36_17685	COG2201	protein-glutamate methylesterase activity
KCI36_17730	COG0583	DNA-binding transcription factor activity
KCI36_17790	COG3039	Transposase
KCI36_17810	COG1278	Cold shock
KCI36_17820	COG3328	transposase activity
KCI36_17840	COG3039	Transposase
KCI36_17850	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KCI36_17885	COG0557	exoribonuclease II activity
KCI36_17910	COG1960	acyl-CoA dehydrogenase activity
KCI36_17915	COG2226	methyltransferase
KCI36_17920	COG1410	methionine synthase
KCI36_17920	COG0646	methionine synthase
KCI36_17925	COG0646	methionine synthase
KCI36_17925	COG1410	methionine synthase
KCI36_17935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KCI36_17945	COG1609	Transcriptional regulator
KCI36_17960	COG2900	Belongs to the SlyX family
KCI36_17975	COG0386	Belongs to the glutathione peroxidase family
KCI36_17985	COG1725	Transcriptional regulator
KCI36_17990	COG1131	(ABC) transporter
KCI36_18070	COG2850	peptidyl-arginine hydroxylation
KCI36_18105	COG1132	(ABC) transporter
KCI36_18120	COG0583	DNA-binding transcription factor activity
KCI36_18135	COG1605	Chorismate mutase
KCI36_18135	COG0287	Prephenate dehydrogenase
KCI36_18140	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
KCI36_18145	COG0484	heat shock protein binding
KCI36_18150	COG0443	Heat shock 70 kDa protein
KCI36_18155	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KCI36_18165	COG0497	DNA recombination
KCI36_18175	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KCI36_18180	COG2914	Belongs to the UPF0125 (RnfH) family
KCI36_18205	COG1960	acyl-CoA dehydrogenase activity
KCI36_18215	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KCI36_18260	COG2814	Major facilitator Superfamily
KCI36_18265	COG1566	PFAM secretion protein HlyD family protein
KCI36_18300	COG4774	siderophore transport
KCI36_18310	COG0367	asparagine synthase
KCI36_18325	COG1393	Belongs to the ArsC family
KCI36_18385	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KCI36_18400	COG0233	cytoplasmic translational termination
KCI36_18410	COG0575	Belongs to the CDS family
KCI36_18420	COG0750	zinc metalloprotease
KCI36_18435	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KCI36_18440	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KCI36_18460	COG0825	malonyl-CoA metabolic process
KCI36_18470	COG4771	TonB-dependent receptor
KCI36_18475	COG1131	(ABC) transporter
KCI36_18495	COG1981	membrane
KCI36_18540	COG0529	Catalyzes the synthesis of activated sulfate
KCI36_18540	COG2895	sulfate adenylyltransferase (ATP) activity
KCI36_18575	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KCI36_18590	COG2040	homocysteine
KCI36_18595	COG0833	amino acid
KCI36_18615	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KCI36_18615	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KCI36_18625	COG2878	Part of a membrane complex involved in electron transport
KCI36_18645	COG1595	DNA-templated transcription, initiation
KCI36_18670	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KCI36_18685	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KCI36_18690	COG0251	oxidation-reduction process
KCI36_18700	COG0392	lysyltransferase activity
KCI36_18700	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KCI36_18745	COG2814	Major facilitator Superfamily
KCI36_18750	COG1902	pentaerythritol trinitrate reductase activity
KCI36_18760	COG2824	Alkylphosphonate utilization operon protein PhnA
KCI36_18775	COG1047	Peptidyl-prolyl cis-trans
KCI36_18810	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KCI36_18825	COG1451	nucleotide metabolic process
KCI36_18845	COG0183	Belongs to the thiolase family
KCI36_18875	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KCI36_18875	COG1793	dna ligase
KCI36_18885	COG1793	dna ligase
KCI36_18890	COG1201	RNA secondary structure unwinding
KCI36_18910	COG1278	Cold shock
KCI36_18915	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KCI36_18920	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KCI36_18930	COG3046	protein related to deoxyribodipyrimidine photolyase
KCI36_18935	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
KCI36_18940	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KCI36_18955	COG2954	triphosphatase activity
KCI36_18970	COG1381	Involved in DNA repair and RecF pathway recombination
KCI36_19000	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KCI36_19015	COG1250	3-hydroxyacyl-CoA dehydrogenase
KCI36_19015	COG1024	Enoyl-CoA hydratase
KCI36_19035	COG1024	Enoyl-CoA hydratase
KCI36_19040	COG1960	acyl-CoA dehydrogenase activity
KCI36_19060	COG3867	Arabinogalactan endo-beta-1,4-galactanase
KCI36_19110	COG2353	YceI-like domain
KCI36_19120	COG2353	YceI-like domain
KCI36_19135	COG1760	l-serine dehydratase
KCI36_19145	COG0626	cystathionine gamma-synthase activity
KCI36_19150	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KCI36_19155	COG0739	heme binding
KCI36_19165	COG1272	protein, Hemolysin III
KCI36_19185	COG0463	Glycosyl transferase, family 2
KCI36_19195	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KCI36_19205	COG4771	TonB-dependent receptor
KCI36_19210	COG1309	transcriptional regulator
KCI36_19220	COG1960	acyl-CoA dehydrogenase activity
KCI36_19255	COG0509	glycine decarboxylation via glycine cleavage system
KCI36_19270	COG0330	HflC and HflK could
KCI36_19285	COG3956	TIGRFAM MazG family protein
KCI36_19295	COG0494	nUDIX hydrolase
KCI36_19305	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KCI36_19310	COG0837	glucose binding
KCI36_19325	COG1388	LysM domain
KCI36_19325	COG3858	chitin binding
KCI36_19335	COG3525	Glycosyl hydrolase, family 20, catalytic domain
KCI36_19345	COG1472	Belongs to the glycosyl hydrolase 3 family
KCI36_19420	COG3537	Alpha-1,2-mannosidase
KCI36_19470	COG3142	Participates in the control of copper homeostasis
KCI36_19475	COG1446	asparaginase
KCI36_19510	COG0745	RESPONSE REGULATOR receiver
KCI36_19520	COG0840	transmembrane signaling receptor activity
KCI36_19525	COG0835	chemotaxis
KCI36_19540	COG0189	ligase activity
KCI36_19550	COG1397	ADP-ribosylglycohydrolase
KCI36_19560	COG1199	ATP-dependent helicase activity
KCI36_19570	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KCI36_19575	COG1215	transferase activity, transferring glycosyl groups
KCI36_19585	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KCI36_19640	COG1643	Atp-dependent helicase
KCI36_19645	COG0783	Belongs to the Dps family
KCI36_19650	COG0514	ATP-dependent DNA helicase (RecQ)
KCI36_19670	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KCI36_19710	COG4695	Portal protein
KCI36_19755	COG3179	chitinase
KCI36_19930	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KCI36_19980	COG1187	pseudouridine synthase activity
KCI36_19985	COG0602	queuosine metabolic process
KCI36_19995	COG2885	chlorophyll binding
KCI36_20010	COG0848	biopolymer transport protein
KCI36_20020	COG0824	Thioesterase
KCI36_20025	COG2255	four-way junction helicase activity
KCI36_20035	COG0632	four-way junction helicase activity
KCI36_20140	COG3209	COG3209 Rhs family protein
KCI36_20140	COG3209	COG3209 Rhs family protein
KCI36_20160	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KCI36_20165	COG1845	cytochrome c oxidase, subunit III
KCI36_20170	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KCI36_20185	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KCI36_20190	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KCI36_20200	COG0196	riboflavin kinase activity
KCI36_20205	COG0728	peptidoglycan biosynthetic process
KCI36_20210	COG0268	Binds directly to 16S ribosomal RNA
KCI36_20215	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KCI36_20220	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KCI36_20230	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KCI36_20235	COG0824	Thioesterase
KCI36_20250	COG1946	Acyl-CoA thioesterase
KCI36_20260	COG1595	DNA-templated transcription, initiation
KCI36_20280	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
KCI36_20315	COG1877	trehalose-phosphatase activity
KCI36_20320	COG3387	PFAM Glycoside hydrolase 15-related
KCI36_20345	COG0564	pseudouridine synthase activity
KCI36_20350	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KCI36_20355	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KCI36_20355	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KCI36_20365	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KCI36_20370	COG0045	succinate-CoA ligase (ADP-forming) activity
KCI36_20410	COG2194	sulfuric ester hydrolase activity
KCI36_20415	COG4969	Belongs to the N-Me-Phe pilin family
KCI36_20425	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KCI36_20515	COG1132	(ABC) transporter
KCI36_20545	COG0745	RESPONSE REGULATOR receiver
KCI36_20550	COG5000	phosphorelay sensor kinase activity
KCI36_20550	COG5002	protein histidine kinase activity
KCI36_20555	COG0475	glutathione-regulated potassium exporter activity
KCI36_20565	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KCI36_20585	COG1187	pseudouridine synthase activity
KCI36_20590	COG5001	Diguanylate cyclase
KCI36_20590	COG5002	protein histidine kinase activity
KCI36_20695	COG1028	Short-chain dehydrogenase reductase Sdr
KCI36_20710	COG0415	Belongs to the DNA photolyase family
KCI36_20715	COG0305	Participates in initiation and elongation during chromosome replication
KCI36_20725	COG0367	asparagine synthase
KCI36_20740	COG1960	acyl-CoA dehydrogenase activity
KCI36_20755	COG0084	hydrolase, TatD family'
KCI36_20760	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KCI36_20820	COG0735	belongs to the Fur family
KCI36_20825	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KCI36_20860	COG3039	Transposase
KCI36_20880	COG3039	Transposase
KCI36_20900	COG3039	Transposase
KCI36_20915	COG2205	protein histidine kinase activity
KCI36_20925	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KCI36_20935	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KCI36_20950	COG2198	Histidine kinase
KCI36_20950	COG0643	Histidine kinase
KCI36_20955	COG0840	transmembrane signaling receptor activity
KCI36_20960	COG0835	chemotaxis
KCI36_20965	COG2202	Pas domain
KCI36_20965	COG2200	EAL domain
KCI36_20965	COG2199	diguanylate cyclase activity
KCI36_20970	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KCI36_20985	COG3590	peptidase
KCI36_21005	COG1515	deoxyribonuclease V activity
KCI36_21010	COG1741	Belongs to the pirin family
KCI36_21100	COG1741	Belongs to the pirin family
KCI36_21105	COG1966	Carbon starvation protein
KCI36_21110	COG2879	small protein
KCI36_21145	COG5001	Diguanylate cyclase
KCI36_21145	COG2203	Gaf domain
KCI36_21145	COG4251	negative regulation of phosphorylation
KCI36_21145	COG3706	GGDEF domain
KCI36_21150	COG0629	single-stranded DNA binding
KCI36_21155	COG0142	geranyltranstransferase activity
KCI36_21180	COG0527	aspartate kinase activity
KCI36_21190	COG0384	phenazine biosynthesis protein PhzF
KCI36_21200	COG1764	response to oxidative stress
KCI36_21215	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KCI36_21220	COG1678	Uncharacterized ACR, COG1678
KCI36_21230	COG0519	Catalyzes the synthesis of GMP from XMP
KCI36_21260	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KCI36_21300	COG0693	protein deglycase activity
KCI36_21320	COG1959	2 iron, 2 sulfur cluster binding
KCI36_21325	COG0719	Fe-S assembly protein
KCI36_21330	COG0396	ATPase activity
KCI36_21335	COG0719	Fe-S assembly protein
KCI36_21340	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KCI36_21350	COG2146	nitrite reductase [NAD(P)H] activity
KCI36_21385	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KCI36_21400	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KCI36_21410	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
KCI36_21415	COG0174	glutamine synthetase
KCI36_21445	COG0326	Molecular chaperone. Has ATPase activity
KCI36_21450	COG2207	Transcriptional regulator
KCI36_21475	COG2755	lipolytic protein G-D-S-L family
KCI36_21475	COG0657	acetylesterase activity
KCI36_21500	COG0488	(ABC) transporter
KCI36_21535	COG4651	solute:proton antiporter activity
KCI36_21535	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KCI36_21550	COG4772	TonB-dependent receptor
KCI36_21560	COG4264	IucA IucC family
KCI36_21565	COG2814	Major facilitator Superfamily
KCI36_21575	COG0019	diaminopimelate decarboxylase activity
KCI36_21635	COG4206	TonB-dependent receptor
KCI36_21670	COG0542	response to heat
KCI36_21705	COG0534	Mate efflux family protein
KCI36_21720	COG0336	Belongs to the RNA methyltransferase TrmD family
KCI36_21725	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KCI36_21730	COG0228	four-way junction DNA binding
KCI36_21750	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KCI36_21760	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KCI36_21805	COG1555	photosystem II stabilization
KCI36_21810	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KCI36_21825	COG3178	'Phosphotransferase
KCI36_21830	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KCI36_21840	COG0628	permease
KCI36_21850	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KCI36_21865	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KCI36_21885	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KCI36_21890	COG0271	Belongs to the BolA IbaG family
KCI36_21900	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KCI36_21910	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
KCI36_21915	COG1137	ATPase activity
KCI36_21930	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KCI36_21935	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KCI36_21940	COG1660	Displays ATPase and GTPase activities
KCI36_21950	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KCI36_21955	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KCI36_21960	COG2239	Acts as a magnesium transporter
KCI36_21970	COG1294	oxidase, subunit
KCI36_21975	COG1271	oxidase subunit
KCI36_21990	COG1113	amino acid transport
KCI36_22005	COG2197	response regulator
KCI36_22010	COG0531	amino acid
KCI36_22065	COG0754	glutathionylspermidine amidase activity
KCI36_22090	COG1842	Phage shock protein A
KCI36_22105	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KCI36_22150	COG2201	protein-glutamate methylesterase activity
KCI36_22175	COG2801	Transposase and inactivated derivatives
KCI36_22240	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KCI36_22245	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KCI36_22285	COG0745	RESPONSE REGULATOR receiver
KCI36_22290	COG2205	protein histidine kinase activity
KCI36_22300	COG3293	Transposase
KCI36_22310	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KCI36_22340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KCI36_22340	COG3453	Protein conserved in bacteria
KCI36_22345	COG0725	ABC transporter, periplasmic molybdate-binding protein
KCI36_22350	COG4149	molybdate abc transporter
KCI36_22355	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KCI36_22375	COG0642	Histidine kinase
KCI36_22390	COG1028	Short-chain dehydrogenase reductase Sdr
KCI36_22400	COG1022	Amp-dependent synthetase and ligase
KCI36_22425	COG1376	ErfK ybiS ycfS ynhG family protein
KCI36_22430	COG0739	heme binding
KCI36_22440	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KCI36_22445	COG1301	dicarboxylic acid transport
KCI36_22465	COG2304	oxidoreductase activity
KCI36_22485	COG0714	Associated with various cellular activities
KCI36_22535	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KCI36_22560	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KCI36_22570	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KCI36_22595	COG1561	YicC-like family, N-terminal region
KCI36_22600	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KCI36_22615	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KCI36_22655	COG0006	proline dipeptidase activity
KCI36_22680	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KCI36_22700	COG2912	Transglutaminase-like superfamily
KCI36_22705	COG1773	rubredoxin
KCI36_22710	COG0352	thiamine-phosphate diphosphorylase activity
KCI36_22735	COG0281	malic enzyme
KCI36_22735	COG0280	phosphate acetyltransferase
KCI36_22755	COG4191	Histidine kinase
KCI36_22770	COG0583	DNA-binding transcription factor activity
KCI36_22785	COG2197	response regulator
KCI36_22795	COG0642	Histidine kinase
KCI36_22815	COG2851	Citrate transporter
KCI36_22820	COG1028	Short-chain dehydrogenase reductase Sdr
KCI36_22825	COG1609	Transcriptional regulator
KCI36_22835	COG2211	Major facilitator Superfamily
KCI36_22885	COG0726	polysaccharide deacetylase
KCI36_22890	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KCI36_22915	COG3039	Transposase
KCI36_22960	COG0242	peptide deformylase activity
KCI36_22980	COG0714	Associated with various cellular activities
KCI36_23000	COG0537	adenosine 5'-monophosphoramidase activity
KCI36_23030	COG0314	molybdopterin synthase activity
KCI36_23035	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KCI36_23040	COG0315	cyclic pyranopterin monophosphate synthase activity
KCI36_23050	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KCI36_23055	COG1234	tRNA 3'-trailer cleavage
KCI36_23060	COG3642	lipopolysaccharide core region biosynthetic process
KCI36_23065	COG0859	PFAM glycosyl transferase family 9
KCI36_23075	COG0582	viral genome integration into host DNA
KCI36_23210	COG0489	protein tyrosine kinase activity
KCI36_23250	COG4962	Type ii secretion system protein e
KCI36_23255	COG3838	Conjugal transfer protein Trbc
KCI36_23265	COG3451	type IV secretory pathway VirB4
KCI36_23280	COG3846	protein secretion by the type IV secretion system
KCI36_23315	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone