locus-tag	class	description
EYC54_00025	COG0187	DNA topoisomerase II activity
EYC54_00035	COG0501	Belongs to the peptidase M48B family
EYC54_00065	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EYC54_00120	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EYC54_00130	COG0793	Belongs to the peptidase S41A family
EYC54_00135	COG4942	peptidase
EYC54_00145	COG2234	aminopeptidase activity
EYC54_00155	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EYC54_00170	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EYC54_00180	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EYC54_00190	COG1064	alcohol dehydrogenase
EYC54_00205	COG0493	'glutamate synthase
EYC54_00210	COG0067	glutamate synthase
EYC54_00210	COG0070	glutamate synthase
EYC54_00210	COG0069	glutamate synthase activity
EYC54_00270	COG1111	helicase
EYC54_00270	COG1205	dead DEAH box helicase
EYC54_00275	COG1272	protein, Hemolysin III
EYC54_00295	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EYC54_00305	COG4772	TonB-dependent receptor
EYC54_00325	COG1755	Isoprenylcysteine carboxyl methyltransferase
EYC54_00360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYC54_00395	COG0477	Major facilitator Superfamily
EYC54_00400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYC54_00445	COG3237	CsbD-like
EYC54_00505	COG0246	Mannitol dehydrogenase
EYC54_00510	COG1472	Belongs to the glycosyl hydrolase 3 family
EYC54_00520	COG4948	Mandelate Racemase Muconate Lactonizing
EYC54_00530	COG3661	Belongs to the glycosyl hydrolase 67 family
EYC54_00550	COG0037	tRNA processing
EYC54_00555	COG2974	May be involved in recombination
EYC54_00580	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EYC54_00590	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EYC54_00595	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EYC54_00600	COG0805	protein transport
EYC54_00610	COG0519	Catalyzes the synthesis of GMP from XMP
EYC54_00610	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EYC54_00625	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EYC54_00630	COG0752	glycyl-tRNA synthetase alpha subunit
EYC54_00645	COG0457	Tetratricopeptide repeat
EYC54_00650	COG4771	TonB-dependent receptor
EYC54_00655	COG0729	surface antigen
EYC54_00660	COG2911	Protein conserved in bacteria
EYC54_00680	COG0443	Heat shock 70 kDa protein
EYC54_00705	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EYC54_00715	COG3265	gluconokinase activity
EYC54_00720	COG2211	Major facilitator Superfamily
EYC54_00725	COG3459	Glycosyltransferase 36 associated
EYC54_00735	COG2205	protein histidine kinase activity
EYC54_00745	COG1414	Transcriptional regulator
EYC54_00750	COG0738	Major facilitator superfamily
EYC54_00755	COG3254	rhamnose metabolic process
EYC54_00760	COG4948	Mandelate Racemase Muconate Lactonizing
EYC54_00770	COG0179	Fumarylacetoacetate (FAA) hydrolase
EYC54_00775	COG1028	Short-chain dehydrogenase reductase Sdr
EYC54_00795	COG3507	Belongs to the glycosyl hydrolase 43 family
EYC54_00835	COG3162	membrane
EYC54_00840	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EYC54_00855	COG0708	Exodeoxyribonuclease III
EYC54_00870	COG2091	lysine biosynthetic process via aminoadipic acid
EYC54_00880	COG3540	Alkaline phosphatase
EYC54_00885	COG0357	Ribosomal RNA small subunit methyltransferase G
EYC54_00900	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EYC54_00905	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EYC54_00910	COG2159	amidohydrolase
EYC54_00925	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EYC54_00930	COG0583	DNA-binding transcription factor activity
EYC54_00935	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EYC54_00955	COG0210	DNA helicase
EYC54_01080	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EYC54_01095	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EYC54_01140	COG1028	Short-chain dehydrogenase reductase Sdr
EYC54_01155	COG0463	Glycosyl transferase, family 2
EYC54_01165	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EYC54_01170	COG3100	YcgL domain-containing protein
EYC54_01185	COG3387	PFAM Glycoside hydrolase 15-related
EYC54_01190	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EYC54_01220	COG2239	Acts as a magnesium transporter
EYC54_01230	COG1042	CoA-binding domain protein
EYC54_01230	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EYC54_01230	COG0045	succinate-CoA ligase (ADP-forming) activity
EYC54_01245	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EYC54_01255	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EYC54_01290	COG1764	response to oxidative stress
EYC54_01295	COG1846	Transcriptional regulator
EYC54_01300	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EYC54_01310	COG0697	spore germination
EYC54_01325	COG0523	cobalamin synthesis protein
EYC54_01370	COG1960	acyl-CoA dehydrogenase activity
EYC54_01375	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EYC54_01435	COG0339	signal peptide processing
EYC54_01465	COG0564	pseudouridine synthase activity
EYC54_01495	COG1181	Belongs to the D-alanine--D-alanine ligase family
EYC54_01495	COG1181	Belongs to the D-alanine--D-alanine ligase family
EYC54_01510	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EYC54_01515	COG0318	PFAM AMP-dependent synthetase and ligase
EYC54_01525	COG0596	Alpha beta hydrolase
EYC54_01530	COG3177	Filamentation induced by cAMP protein fic
EYC54_01535	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EYC54_01550	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EYC54_01575	COG4191	Histidine kinase
EYC54_01580	COG0028	Belongs to the TPP enzyme family
EYC54_01615	COG0656	L-ascorbic acid biosynthetic process
EYC54_01620	COG2130	NADP-dependent
EYC54_01625	COG0667	Aldo Keto reductase
EYC54_01635	COG1187	pseudouridine synthase activity
EYC54_01650	COG1643	Atp-dependent helicase
EYC54_01660	COG4807	Protein conserved in bacteria
EYC54_01665	COG2072	flavoprotein involved in K transport
EYC54_01685	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EYC54_01745	COG0084	hydrolase, TatD family'
EYC54_01765	COG0583	DNA-binding transcription factor activity
EYC54_01770	COG2814	Major facilitator Superfamily
EYC54_01780	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EYC54_01785	COG1902	pentaerythritol trinitrate reductase activity
EYC54_01835	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EYC54_01840	COG0583	DNA-binding transcription factor activity
EYC54_01870	COG0702	epimerase
EYC54_01875	COG1733	regulation of RNA biosynthetic process
EYC54_01900	COG3501	Rhs element vgr protein
EYC54_01920	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EYC54_02000	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EYC54_02005	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EYC54_02015	COG3485	protocatechuate 3,4-dioxygenase
EYC54_02020	COG3485	protocatechuate 3,4-dioxygenase
EYC54_02035	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EYC54_02040	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EYC54_02055	COG1414	Transcriptional regulator
EYC54_02075	COG3541	Predicted nucleotidyltransferase
EYC54_02145	COG1040	competence protein
EYC54_02150	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EYC54_02245	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EYC54_02320	COG3264	Mechanosensitive ion channel
EYC54_02320	COG1511	domain protein
EYC54_02335	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EYC54_02345	COG2354	Protein conserved in bacteria
EYC54_02355	COG0745	RESPONSE REGULATOR receiver
EYC54_02355	COG3706	GGDEF domain
EYC54_02370	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EYC54_02395	COG0702	epimerase
EYC54_02410	COG1858	cytochrome C peroxidase
EYC54_02485	COG1028	Short-chain dehydrogenase reductase Sdr
EYC54_02515	COG0513	Belongs to the DEAD box helicase family
EYC54_02525	COG3039	Transposase
EYC54_02540	COG0508	dehydrogenase complex catalyzes the overall conversion of
EYC54_02555	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EYC54_02570	COG3104	oligopeptide transport
EYC54_02600	COG1320	monovalent cation:proton antiporter activity
EYC54_02605	COG2212	antiporter activity
EYC54_02615	COG0651	ATP synthesis coupled electron transport
EYC54_02620	COG1006	Multisubunit Na H antiporter MnhC subunit
EYC54_02625	COG2111	Na H antiporter
EYC54_02625	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EYC54_02660	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EYC54_02670	COG0456	acetyltransferase
EYC54_02715	COG0134	indole-3-glycerol-phosphate synthase activity
EYC54_02725	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EYC54_02745	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EYC54_02825	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
EYC54_02845	COG2814	Major facilitator Superfamily
EYC54_02855	COG2814	Major facilitator Superfamily
EYC54_02860	COG1289	transmembrane transporter activity
EYC54_02870	COG0151	Belongs to the GarS family
EYC54_02880	COG0138	bifunctional purine biosynthesis protein purh
EYC54_02930	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EYC54_02980	COG0439	Biotin carboxylase
EYC54_02990	COG0511	ligase activity, forming carbon-carbon bonds
EYC54_03015	COG1324	tolerance protein
EYC54_03020	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EYC54_03040	COG0534	Mate efflux family protein
EYC54_03045	COG0616	signal peptide processing
EYC54_03055	COG1028	Short-chain dehydrogenase reductase Sdr
EYC54_03075	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EYC54_03075	COG1754	DNA topoisomerase type I activity
EYC54_03095	COG0758	DNA mediated transformation
EYC54_03100	COG1652	LysM domain
EYC54_03105	COG0242	peptide deformylase activity
EYC54_03115	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EYC54_03115	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EYC54_03165	COG1560	Kdo2-lipid A biosynthetic process
EYC54_03175	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EYC54_03380	COG1063	alcohol dehydrogenase
EYC54_03415	COG1294	oxidase, subunit
EYC54_03420	COG1271	oxidase subunit
EYC54_03435	COG2204	response regulator
EYC54_03465	COG3546	catalase activity
EYC54_03470	COG3685	Protein conserved in bacteria
EYC54_03490	COG2972	Histidine kinase
EYC54_03505	COG0531	amino acid
EYC54_03525	COG3590	peptidase
EYC54_03540	COG0667	Aldo Keto reductase
EYC54_03555	COG3384	dioxygenase
EYC54_03565	COG1573	uracil-dna glycosylase
EYC54_03575	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EYC54_03585	COG0025	NhaP-type Na H and K H
EYC54_03590	COG1131	(ABC) transporter
EYC54_03595	COG0842	Transport permease protein
EYC54_03610	COG1404	Belongs to the peptidase S8 family
EYC54_03625	COG0745	RESPONSE REGULATOR receiver
EYC54_03670	COG1522	sequence-specific DNA binding
EYC54_03675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYC54_03700	COG2205	protein histidine kinase activity
EYC54_03700	COG2202	Pas domain
EYC54_03730	COG2813	Specifically methylates the guanine in position
EYC54_03735	COG1187	pseudouridine synthase activity
EYC54_03740	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EYC54_03780	COG0697	spore germination
EYC54_03790	COG2011	ABC-type metal ion transport system permease component
EYC54_03830	COG0508	dehydrogenase complex catalyzes the overall conversion of
EYC54_03840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EYC54_03860	COG0356	it plays a direct role in the translocation of protons across the membrane
EYC54_03870	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EYC54_03970	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EYC54_04015	COG0339	signal peptide processing
EYC54_04045	COG0546	phosphoglycolate phosphatase activity
EYC54_04055	COG1956	GAF domain-containing protein
EYC54_04070	COG0720	synthase
EYC54_04080	COG0513	Belongs to the DEAD box helicase family
EYC54_04095	COG0625	glutathione transferase activity
EYC54_04125	COG0626	cystathionine gamma-synthase activity
EYC54_04145	COG1216	Glycosyl transferase, family 2
EYC54_04145	COG0438	transferase activity, transferring glycosyl groups
EYC54_04175	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
EYC54_04180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EYC54_04195	COG0277	FAD linked oxidase domain protein
EYC54_04200	COG0546	phosphoglycolate phosphatase activity
EYC54_04200	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EYC54_04215	COG2086	electron transfer activity
EYC54_04240	COG0662	Cupin 2, conserved barrel domain protein
EYC54_04240	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
EYC54_04245	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EYC54_04285	COG3218	ABC-type transport auxiliary lipoprotein component
EYC54_04285	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EYC54_04290	COG1127	ABC transporter
EYC54_04295	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EYC54_04320	COG1183	phosphatidylcholine synthase activity
EYC54_04350	COG0525	valine-tRNA ligase activity
EYC54_04375	COG0795	lipopolysaccharide-transporting ATPase activity
EYC54_04390	COG4974	Belongs to the 'phage' integrase family
EYC54_04395	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EYC54_04410	COG0047	phosphoribosylformylglycinamidine synthase activity
EYC54_04410	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EYC54_04420	COG5295	Hep Hag repeat protein
EYC54_04425	COG1404	Belongs to the peptidase S8 family
EYC54_04430	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EYC54_04440	COG1459	type II secretion system
EYC54_04445	COG2165	general secretion pathway protein
EYC54_04450	COG4970	Tfp pilus assembly protein FimT
EYC54_04455	COG2165	general secretion pathway protein
EYC54_04460	COG4795	General secretion pathway protein
EYC54_04465	COG3156	type II secretion system protein K
EYC54_04470	COG3166	PFAM Fimbrial assembly family protein
EYC54_04485	COG1450	Type ii and iii secretion system protein
EYC54_04500	COG2188	Transcriptional regulator
EYC54_04555	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EYC54_04575	COG0242	peptide deformylase activity
EYC54_04615	COG0402	S-adenosylhomocysteine deaminase activity
EYC54_04620	COG3964	amidohydrolase
EYC54_04645	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EYC54_04650	COG0726	polysaccharide deacetylase
EYC54_04670	COG0436	Aminotransferase
EYC54_04700	COG2211	Major facilitator Superfamily
EYC54_04710	COG1609	Transcriptional regulator
EYC54_04715	COG1028	Short-chain dehydrogenase reductase Sdr
EYC54_04720	COG2851	Citrate transporter
EYC54_04740	COG0642	Histidine kinase
EYC54_04745	COG1840	ABC-type Fe3 transport system, periplasmic component
EYC54_04750	COG2197	response regulator
EYC54_04770	COG0583	DNA-binding transcription factor activity
EYC54_04790	COG4191	Histidine kinase
EYC54_04810	COG0281	malic enzyme
EYC54_04810	COG0280	phosphate acetyltransferase
EYC54_04840	COG1560	Kdo2-lipid A biosynthetic process
EYC54_04845	COG1519	Transferase
EYC54_04850	COG1538	Outer membrane efflux protein
EYC54_04855	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EYC54_04870	COG5001	Diguanylate cyclase
EYC54_04870	COG3300	MHYT domain
EYC54_04890	COG2226	methyltransferase
EYC54_04935	COG3710	Transcriptional regulator
EYC54_04960	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EYC54_04970	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
EYC54_04995	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EYC54_05005	COG3781	membrane
EYC54_05015	COG0671	phosphoesterase, PA-phosphatase related
EYC54_05025	COG1028	Short-chain dehydrogenase reductase Sdr
EYC54_05040	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EYC54_05045	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EYC54_05085	COG2197	response regulator
EYC54_05110	COG0352	thiamine-phosphate diphosphorylase activity
EYC54_05115	COG1773	rubredoxin
EYC54_05120	COG2912	Transglutaminase-like superfamily
EYC54_05140	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EYC54_05165	COG0006	proline dipeptidase activity
EYC54_05195	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EYC54_05205	COG0346	lactoylglutathione lyase activity
EYC54_05215	COG1561	YicC-like family, N-terminal region
EYC54_05230	COG1758	RNA polymerase activity
EYC54_05235	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EYC54_05245	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EYC54_05255	COG0254	rRNA binding
EYC54_05275	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EYC54_05310	COG0714	Associated with various cellular activities
EYC54_05330	COG2304	oxidoreductase activity
EYC54_05350	COG1301	dicarboxylic acid transport
EYC54_05355	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EYC54_05370	COG0739	heme binding
EYC54_05375	COG1376	ErfK ybiS ycfS ynhG family protein
EYC54_05415	COG1028	Short-chain dehydrogenase reductase Sdr
EYC54_05430	COG0642	Histidine kinase
EYC54_05450	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EYC54_05455	COG4149	molybdate abc transporter
EYC54_05460	COG0725	ABC transporter, periplasmic molybdate-binding protein
EYC54_05465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EYC54_05465	COG3453	Protein conserved in bacteria
EYC54_05475	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EYC54_05500	COG0469	pyruvate kinase activity
EYC54_05510	COG3588	fructose-bisphosphate aldolase
EYC54_05515	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EYC54_05570	COG0784	Response regulator, receiver
EYC54_05570	COG2198	Histidine kinase
EYC54_05570	COG2205	protein histidine kinase activity
EYC54_05600	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EYC54_05610	COG0529	Catalyzes the synthesis of activated sulfate
EYC54_05610	COG2895	sulfate adenylyltransferase (ATP) activity
EYC54_05620	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EYC54_05625	COG0308	aminopeptidase N
EYC54_05645	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EYC54_05660	COG1970	mechanosensitive ion channel activity
EYC54_05685	COG0471	metal ion transport
EYC54_05685	COG3273	potassium ion transport
EYC54_05790	COG0189	ligase activity
EYC54_05800	COG0745	RESPONSE REGULATOR receiver
EYC54_05805	COG2205	protein histidine kinase activity
EYC54_05810	COG0237	dephospho-CoA kinase activity
EYC54_05815	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EYC54_05830	COG2194	sulfuric ester hydrolase activity
EYC54_05870	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EYC54_05885	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EYC54_05885	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EYC54_05890	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EYC54_05895	COG0564	pseudouridine synthase activity
EYC54_05910	COG3011	Protein conserved in bacteria
EYC54_05915	COG0840	transmembrane signaling receptor activity
EYC54_05930	COG3387	PFAM Glycoside hydrolase 15-related
EYC54_05935	COG1877	trehalose-phosphatase activity
EYC54_06000	COG1946	Acyl-CoA thioesterase
EYC54_06015	COG0824	Thioesterase
EYC54_06020	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EYC54_06040	COG0268	Binds directly to 16S ribosomal RNA
EYC54_06045	COG0728	peptidoglycan biosynthetic process
EYC54_06050	COG0196	riboflavin kinase activity
EYC54_06060	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EYC54_06080	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EYC54_06085	COG1845	cytochrome c oxidase, subunit III
EYC54_06090	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EYC54_06100	COG3501	Rhs element vgr protein
EYC54_06110	COG3209	COG3209 Rhs family protein
EYC54_06145	COG3209	COG3209 Rhs family protein
EYC54_06155	COG3039	Transposase
EYC54_06225	COG2207	Transcriptional regulator
EYC54_06230	COG0326	Molecular chaperone. Has ATPase activity
EYC54_06240	COG1366	Belongs to the anti-sigma-factor antagonist family
EYC54_06245	COG1366	Belongs to the anti-sigma-factor antagonist family
EYC54_06250	COG2172	sigma factor antagonist activity
EYC54_06290	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EYC54_06300	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EYC54_06315	COG2070	2-Nitropropane dioxygenase
EYC54_06350	COG0534	Mate efflux family protein
EYC54_06360	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EYC54_06385	COG0542	response to heat
EYC54_06420	COG3039	Transposase
EYC54_06465	COG4206	TonB-dependent receptor
EYC54_06500	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EYC54_06520	COG0019	diaminopimelate decarboxylase activity
EYC54_06535	COG4264	IucA IucC family
EYC54_06545	COG4772	TonB-dependent receptor
EYC54_06560	COG4651	solute:proton antiporter activity
EYC54_06560	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EYC54_06590	COG0488	(ABC) transporter
EYC54_06610	COG2755	lipolytic protein G-D-S-L family
EYC54_06610	COG0657	acetylesterase activity
EYC54_06625	COG0477	Major facilitator Superfamily
EYC54_06640	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EYC54_06660	COG0217	transcriptional regulatory protein
EYC54_06665	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EYC54_06685	COG0824	Thioesterase
EYC54_06710	COG0823	Involved in the tonB-independent uptake of proteins
EYC54_06715	COG2885	chlorophyll binding
EYC54_06725	COG0602	queuosine metabolic process
EYC54_06775	COG3501	Rhs element vgr protein
EYC54_06870	COG0740	serine-type endopeptidase activity
EYC54_06875	COG4695	Portal protein
EYC54_06880	COG1802	Transcriptional regulator
EYC54_06880	COG4626	Terminase
EYC54_07025	COG1187	pseudouridine synthase activity
EYC54_07045	COG0514	ATP-dependent DNA helicase (RecQ)
EYC54_07055	COG0783	Belongs to the Dps family
EYC54_07060	COG1643	Atp-dependent helicase
EYC54_07110	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EYC54_07125	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EYC54_07135	COG1199	ATP-dependent helicase activity
EYC54_07155	COG0189	ligase activity
EYC54_07170	COG0835	chemotaxis
EYC54_07175	COG0840	transmembrane signaling receptor activity
EYC54_07210	COG1446	asparaginase
EYC54_07215	COG3142	Participates in the control of copper homeostasis
EYC54_07260	COG3537	Alpha-1,2-mannosidase
EYC54_07270	COG3039	Transposase
EYC54_07310	COG1472	Belongs to the glycosyl hydrolase 3 family
EYC54_07330	COG3858	chitin binding
EYC54_07330	COG1388	LysM domain
EYC54_07345	COG0837	glucose binding
EYC54_07350	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EYC54_07360	COG0494	nUDIX hydrolase
EYC54_07375	COG3956	TIGRFAM MazG family protein
EYC54_07380	COG1742	UPF0060 membrane protein
EYC54_07390	COG0330	HflC and HflK could
EYC54_07435	COG1960	acyl-CoA dehydrogenase activity
EYC54_07445	COG1309	transcriptional regulator
EYC54_07450	COG4771	TonB-dependent receptor
EYC54_07460	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EYC54_07470	COG0463	Glycosyl transferase, family 2
EYC54_07475	COG0517	IMP dehydrogenase activity
EYC54_07475	COG0516	GMP reductase activity
EYC54_07480	COG2982	Protein involved in outer membrane biogenesis
EYC54_07485	COG1272	protein, Hemolysin III
EYC54_07495	COG0739	heme binding
EYC54_07500	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EYC54_07505	COG0626	cystathionine gamma-synthase activity
EYC54_07510	COG0460	homoserine dehydrogenase
EYC54_07510	COG0527	aspartate kinase activity
EYC54_07515	COG1760	l-serine dehydratase
EYC54_07540	COG2353	YceI-like domain
EYC54_07545	COG0784	Response regulator, receiver
EYC54_07545	COG2205	protein histidine kinase activity
EYC54_07545	COG2198	Histidine kinase
EYC54_07550	COG0784	Response regulator, receiver
EYC54_07550	COG5002	protein histidine kinase activity
EYC54_07615	COG1960	acyl-CoA dehydrogenase activity
EYC54_07655	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EYC54_07705	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EYC54_07710	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
EYC54_07715	COG3046	protein related to deoxyribodipyrimidine photolyase
EYC54_07730	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EYC54_07735	COG1278	Cold shock
EYC54_07740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EYC54_07755	COG1201	RNA secondary structure unwinding
EYC54_07760	COG1793	dna ligase
EYC54_07770	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EYC54_07770	COG1793	dna ligase
EYC54_07785	COG0745	RESPONSE REGULATOR receiver
EYC54_07785	COG3706	GGDEF domain
EYC54_07800	COG0183	Belongs to the thiolase family
EYC54_07820	COG1451	nucleotide metabolic process
EYC54_07835	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EYC54_07875	COG1047	Peptidyl-prolyl cis-trans
EYC54_07885	COG2824	Alkylphosphonate utilization operon protein PhnA
EYC54_07900	COG1902	pentaerythritol trinitrate reductase activity
EYC54_07905	COG2814	Major facilitator Superfamily
EYC54_07955	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EYC54_07955	COG0392	lysyltransferase activity
EYC54_07965	COG0251	oxidation-reduction process
EYC54_07970	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EYC54_07985	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EYC54_08010	COG1595	DNA-templated transcription, initiation
EYC54_08030	COG2878	Part of a membrane complex involved in electron transport
EYC54_08050	COG0346	lactoylglutathione lyase activity
EYC54_08055	COG0833	amino acid
EYC54_08060	COG2040	homocysteine
EYC54_08075	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EYC54_08105	COG1695	Transcriptional regulator
EYC54_08155	COG0825	malonyl-CoA metabolic process
EYC54_08185	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EYC54_08200	COG0750	zinc metalloprotease
EYC54_08205	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EYC54_08210	COG0575	Belongs to the CDS family
EYC54_08230	COG0745	RESPONSE REGULATOR receiver
EYC54_08230	COG3706	GGDEF domain
EYC54_08275	COG0024	Methionine aminopeptidase
EYC54_08295	COG1393	Belongs to the ArsC family
EYC54_08305	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EYC54_08310	COG0367	asparagine synthase
EYC54_08320	COG4774	siderophore transport
EYC54_08350	COG2207	Transcriptional regulator
EYC54_08365	COG1566	PFAM secretion protein HlyD family protein
EYC54_08370	COG2814	Major facilitator Superfamily
EYC54_08465	COG0339	signal peptide processing
EYC54_08475	COG0386	Belongs to the glutathione peroxidase family
EYC54_08525	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EYC54_08540	COG0840	transmembrane signaling receptor activity
EYC54_08580	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EYC54_08585	COG0084	hydrolase, TatD family'
EYC54_08600	COG1960	acyl-CoA dehydrogenase activity
EYC54_08615	COG0367	asparagine synthase
EYC54_08625	COG0305	Participates in initiation and elongation during chromosome replication
EYC54_08630	COG0415	Belongs to the DNA photolyase family
EYC54_08650	COG1028	Short-chain dehydrogenase reductase Sdr
EYC54_08660	COG3706	GGDEF domain
EYC54_08670	COG3706	GGDEF domain
EYC54_08690	COG0174	glutamine synthetase
EYC54_08695	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EYC54_08705	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EYC54_08750	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EYC54_08760	COG2914	Belongs to the UPF0125 (RnfH) family
EYC54_08770	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EYC54_08780	COG0497	DNA recombination
EYC54_08795	COG0443	Heat shock 70 kDa protein
EYC54_08810	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EYC54_08840	COG0583	DNA-binding transcription factor activity
EYC54_08850	COG1132	(ABC) transporter
EYC54_08885	COG2850	peptidyl-arginine hydroxylation
EYC54_08910	COG1253	flavin adenine dinucleotide binding
EYC54_08945	COG1131	(ABC) transporter
EYC54_08950	COG1725	Transcriptional regulator
EYC54_08960	COG0386	Belongs to the glutathione peroxidase family
EYC54_09000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYC54_09010	COG0646	methionine synthase
EYC54_09010	COG1410	methionine synthase
EYC54_09015	COG1410	methionine synthase
EYC54_09015	COG0646	methionine synthase
EYC54_09025	COG1960	acyl-CoA dehydrogenase activity
EYC54_09055	COG0557	exoribonuclease II activity
EYC54_09070	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EYC54_09080	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EYC54_09090	COG0704	Plays a role in the regulation of phosphate uptake
EYC54_09105	COG0573	inorganic phosphate transmembrane transporter activity
EYC54_09110	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EYC54_09135	COG0659	secondary active sulfate transmembrane transporter activity
EYC54_09140	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EYC54_09150	COG1024	Enoyl-CoA hydratase
EYC54_09160	COG0494	nUDIX hydrolase
EYC54_09220	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EYC54_09235	COG0667	Aldo Keto reductase
EYC54_09245	COG2925	Exonuclease
EYC54_09255	COG3844	kynureninase activity
EYC54_09270	COG0288	reversible hydration of carbon dioxide
EYC54_09305	COG0316	Belongs to the HesB IscA family
EYC54_09330	COG3115	cell septum assembly
EYC54_09340	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EYC54_09345	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EYC54_09400	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EYC54_09410	COG2986	histidine ammonia-lyase
EYC54_09460	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EYC54_09465	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EYC54_09470	COG1605	Chorismate mutase
EYC54_09470	COG0077	Prephenate dehydratase
EYC54_09495	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EYC54_09510	COG0583	DNA-binding transcription factor activity
EYC54_09540	COG3501	Rhs element vgr protein
EYC54_09590	COG3501	Rhs element vgr protein
EYC54_09610	COG0840	transmembrane signaling receptor activity
EYC54_09625	COG0784	Response regulator, receiver
EYC54_09625	COG4191	Histidine kinase
EYC54_09630	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
EYC54_09635	COG4191	Histidine kinase
EYC54_09635	COG0784	Response regulator, receiver
EYC54_09650	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYC54_09670	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EYC54_09685	COG1595	DNA-templated transcription, initiation
EYC54_09735	COG2244	polysaccharide biosynthetic process
EYC54_09765	COG2264	protein methyltransferase activity
EYC54_09775	COG0438	transferase activity, transferring glycosyl groups
EYC54_09790	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
EYC54_09795	COG1132	(ABC) transporter
EYC54_09805	COG2271	Major facilitator Superfamily
EYC54_09825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EYC54_09840	COG1253	flavin adenine dinucleotide binding
EYC54_09900	COG0148	phosphopyruvate hydratase activity
EYC54_09930	COG2840	Smr protein MutS2
EYC54_09945	COG1238	metal cluster binding
EYC54_09960	COG1534	Rna-binding protein
EYC54_09970	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EYC54_09975	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EYC54_09985	COG1923	regulation of RNA biosynthetic process
EYC54_09990	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EYC54_09995	COG1546	Belongs to the CinA family
EYC54_10020	COG2137	regulation of response to DNA damage stimulus
EYC54_10030	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EYC54_10055	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EYC54_10085	COG1741	Belongs to the pirin family
EYC54_10090	COG0583	DNA-binding transcription factor activity
EYC54_10115	COG0351	phosphomethylpyrimidine kinase
EYC54_10115	COG0352	thiamine-phosphate diphosphorylase activity
EYC54_10125	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EYC54_10130	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EYC54_10145	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EYC54_10155	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EYC54_10160	COG3734	2-keto-3-deoxy-galactonokinase
EYC54_10175	COG0800	Aldolase
EYC54_10200	COG1070	Carbohydrate kinase
EYC54_10210	COG0477	Major facilitator Superfamily
EYC54_10230	COG0860	N-Acetylmuramoyl-L-alanine amidase
EYC54_10245	COG0617	tRNA 3'-terminal CCA addition
EYC54_10265	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EYC54_10295	COG1472	Belongs to the glycosyl hydrolase 3 family
EYC54_10315	COG3706	GGDEF domain
EYC54_10315	COG2203	Gaf domain
EYC54_10315	COG4251	negative regulation of phosphorylation
EYC54_10315	COG5001	Diguanylate cyclase
EYC54_10325	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EYC54_10335	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
EYC54_10350	COG0671	phosphoesterase, PA-phosphatase related
EYC54_10370	COG1794	racemase activity, acting on amino acids and derivatives
EYC54_10380	COG0697	spore germination
EYC54_10385	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EYC54_10405	COG1012	belongs to the aldehyde dehydrogenase family
EYC54_10440	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EYC54_10460	COG0124	histidyl-tRNA synthetase
EYC54_10510	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EYC54_10510	COG0140	phosphoribosyl-ATP diphosphatase activity
EYC54_10535	COG0235	Class ii aldolase
EYC54_10540	COG0531	amino acid
EYC54_10545	COG0531	amino acid
EYC54_10555	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EYC54_10560	COG0277	FAD linked oxidase domain protein
EYC54_10585	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EYC54_10635	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EYC54_10640	COG2258	MOSC domain
EYC54_10645	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EYC54_10650	COG0505	Belongs to the CarA family
EYC54_10660	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EYC54_10665	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EYC54_10675	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EYC54_10690	COG3279	Response regulator of the LytR AlgR family
EYC54_10715	COG2198	Histidine kinase
EYC54_10715	COG0784	Response regulator, receiver
EYC54_10715	COG2205	protein histidine kinase activity
EYC54_10720	COG1024	Enoyl-CoA hydratase
EYC54_10725	COG0318	PFAM AMP-dependent synthetase and ligase
EYC54_10755	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EYC54_10790	COG0840	transmembrane signaling receptor activity
EYC54_10800	COG0835	chemotaxis
EYC54_10825	COG0840	transmembrane signaling receptor activity
EYC54_10830	COG0840	transmembrane signaling receptor activity
EYC54_10835	COG0840	transmembrane signaling receptor activity
EYC54_10840	COG0840	transmembrane signaling receptor activity
EYC54_10845	COG0840	transmembrane signaling receptor activity
EYC54_10855	COG0840	transmembrane signaling receptor activity
EYC54_10860	COG0840	transmembrane signaling receptor activity
EYC54_10865	COG0840	transmembrane signaling receptor activity
EYC54_10880	COG0840	transmembrane signaling receptor activity
EYC54_10910	COG0840	transmembrane signaling receptor activity
EYC54_10920	COG0745	RESPONSE REGULATOR receiver
EYC54_10930	COG0835	chemotaxis
EYC54_10935	COG1192	Involved in chromosome partitioning
EYC54_10940	COG1360	Flagellar Motor Protein
EYC54_10945	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EYC54_10955	COG4774	siderophore transport
EYC54_10960	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EYC54_11065	COG3039	Transposase
EYC54_11115	COG0800	Aldolase
EYC54_11120	COG0129	dihydroxy-acid dehydratase activity
EYC54_11125	COG0363	glucosamine-6-phosphate deaminase activity
EYC54_11135	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EYC54_11150	COG0354	folic acid binding
EYC54_11165	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EYC54_11180	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EYC54_11195	COG4591	ABC-type transport system involved in lipoprotein release permease component
EYC54_11220	COG0811	peptide transport
EYC54_11245	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EYC54_11305	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EYC54_11335	COG1530	ribonuclease E activity
EYC54_11345	COG3064	Membrane
EYC54_11365	COG2154	pterin-4-alpha-carbinolamine dehydratase
EYC54_11405	COG3501	Rhs element vgr protein
EYC54_11520	COG3501	Rhs element vgr protein
EYC54_11555	COG0631	protein serine/threonine phosphatase activity
EYC54_11560	COG0515	serine threonine protein kinase
EYC54_11590	COG1858	cytochrome C peroxidase
EYC54_11635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EYC54_11640	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EYC54_11700	COG3501	Rhs element vgr protein
EYC54_11740	COG4566	intracellular signal transduction
EYC54_11750	COG5001	Diguanylate cyclase
EYC54_11770	COG3685	Protein conserved in bacteria
EYC54_11805	COG1648	precorrin-2 dehydrogenase activity
EYC54_11805	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EYC54_11830	COG0746	molybdenum cofactor guanylyltransferase activity
EYC54_11845	COG0708	Exodeoxyribonuclease III
EYC54_11860	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EYC54_11870	COG0303	'Molybdopterin
EYC54_11875	COG1160	GTP binding
EYC54_11880	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EYC54_11905	COG0105	UTP biosynthetic process
EYC54_11915	COG1250	3-hydroxyacyl-CoA dehydrogenase
EYC54_11915	COG1024	Enoyl-CoA hydratase
EYC54_11920	COG0183	Belongs to the thiolase family
EYC54_11925	COG0038	chloride channel
EYC54_11945	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EYC54_11970	COG1674	ftsk spoiiie
EYC54_11975	COG0492	ferredoxin-NADP+ reductase activity
EYC54_11995	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EYC54_12000	COG0542	response to heat
EYC54_12005	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EYC54_12015	COG0482	sulfurtransferase activity
EYC54_12050	COG4585	Histidine kinase
EYC54_12060	COG5002	protein histidine kinase activity
EYC54_12080	COG0784	Response regulator, receiver
EYC54_12080	COG0835	chemotaxis
EYC54_12090	COG1558	bacterial-type flagellum-dependent cell motility
EYC54_12095	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EYC54_12100	COG1749	Flagellar hook protein flgE
EYC54_12105	COG4787	bacterial-type flagellum-dependent cell motility
EYC54_12110	COG4786	Flagellar basal body rod
EYC54_12115	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EYC54_12120	COG1706	bacterial-type flagellum-dependent cell motility
EYC54_12140	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EYC54_12145	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EYC54_12175	COG2201	protein-glutamate methylesterase activity
EYC54_12180	COG2204	response regulator
EYC54_12195	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EYC54_12205	COG1028	Short-chain dehydrogenase reductase Sdr
EYC54_12240	COG1677	Flagellar hook-basal body complex protein FliE
EYC54_12290	COG3190	flagellar
EYC54_12305	COG1987	bacterial-type flagellum assembly
EYC54_12310	COG1684	flagellar biosynthetic protein fliR
EYC54_12315	COG5001	Diguanylate cyclase
EYC54_12315	COG3300	MHYT domain
EYC54_12320	COG3300	MHYT domain
EYC54_12320	COG5001	Diguanylate cyclase
EYC54_12345	COG0455	bacterial-type flagellum organization
EYC54_12365	COG0643	Histidine kinase
EYC54_12365	COG2198	Histidine kinase
EYC54_12465	COG2205	protein histidine kinase activity
EYC54_12465	COG0784	Response regulator, receiver
EYC54_12480	COG2183	response to ionizing radiation
EYC54_12490	COG0723	plastoquinol--plastocyanin reductase activity
EYC54_12490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYC54_12505	COG3243	poly(R)-hydroxyalkanoic acid synthase
EYC54_12515	COG1183	phosphatidylcholine synthase activity
EYC54_12520	COG1028	Short-chain dehydrogenase reductase Sdr
EYC54_12535	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EYC54_12545	COG0668	transmembrane transport
EYC54_12555	COG0590	tRNA wobble adenosine to inosine editing
EYC54_12560	COG1321	iron dependent repressor
EYC54_12565	COG1914	H( )-stimulated, divalent metal cation uptake system
EYC54_12590	COG0583	DNA-binding transcription factor activity
EYC54_12620	COG0583	DNA-binding transcription factor activity
EYC54_12625	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EYC54_12635	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EYC54_12635	COG0519	Catalyzes the synthesis of GMP from XMP
EYC54_12660	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EYC54_12670	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EYC54_12675	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EYC54_12690	COG0539	negative regulation of cytoplasmic translation
EYC54_12695	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EYC54_12700	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EYC54_12710	COG2957	Belongs to the agmatine deiminase family
EYC54_12720	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EYC54_12745	COG0395	ABC-type sugar transport system, permease component
EYC54_12750	COG1175	transmembrane transport
EYC54_12785	COG2350	Protein conserved in bacteria
EYC54_12790	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EYC54_12795	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EYC54_12800	COG1187	pseudouridine synthase activity
EYC54_12820	COG0436	Aminotransferase
EYC54_12825	COG4133	protoheme IX ABC transporter activity
EYC54_12875	COG1278	Cold shock
EYC54_12885	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EYC54_12890	COG4988	ABC transporter
EYC54_12900	COG1271	oxidase subunit
EYC54_12965	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EYC54_12970	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EYC54_12975	COG0137	argininosuccinate synthase activity
EYC54_12980	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EYC54_12995	COG2166	iron-sulfur cluster assembly
EYC54_13010	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EYC54_13020	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EYC54_13045	COG4677	pectinesterase activity
EYC54_13070	COG0402	S-adenosylhomocysteine deaminase activity
EYC54_13085	COG1509	lysine 2,3-aminomutase activity
EYC54_13090	COG5001	Diguanylate cyclase
EYC54_13090	COG3300	MHYT domain
EYC54_13105	COG0483	inositol monophosphate 1-phosphatase activity
EYC54_13150	COG0513	Belongs to the DEAD box helicase family
EYC54_13160	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EYC54_13170	COG0625	glutathione transferase activity
EYC54_13185	COG4681	YaeQ
EYC54_13190	COG2081	HI0933 family
EYC54_13200	COG0501	Belongs to the peptidase M48B family
EYC54_13210	COG1028	Short-chain dehydrogenase reductase Sdr
EYC54_13235	COG0860	N-Acetylmuramoyl-L-alanine amidase
EYC54_13240	COG0802	atpase or kinase
EYC54_13245	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EYC54_13245	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EYC54_13250	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EYC54_13270	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EYC54_13310	COG0582	viral genome integration into host DNA
EYC54_13370	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EYC54_13470	COG2801	Transposase and inactivated derivatives
EYC54_13480	COG0835	chemotaxis
EYC54_13485	COG0840	transmembrane signaling receptor activity
EYC54_13515	COG2969	positive regulation of protein catabolic process
EYC54_13520	COG0625	glutathione transferase activity
EYC54_13525	COG2857	Cytochrome c1
EYC54_13530	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EYC54_13535	COG0723	plastoquinol--plastocyanin reductase activity
EYC54_13540	COG0741	lytic transglycosylase activity
EYC54_13560	COG1702	phosphate starvation-inducible protein PhoH
EYC54_13580	COG4535	Mg2 and Co2 transporter CorC
EYC54_13595	COG1012	belongs to the aldehyde dehydrogenase family
EYC54_13620	COG1177	transmembrane transport
EYC54_13625	COG1176	ABC-type spermidine putrescine transport system, permease component I
EYC54_13635	COG3842	ATPase activity
EYC54_13655	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EYC54_13685	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EYC54_13690	COG0174	glutamine synthetase
EYC54_13695	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYC54_13700	COG0745	RESPONSE REGULATOR receiver
EYC54_13700	COG3706	GGDEF domain
EYC54_13705	COG0477	Major facilitator Superfamily
EYC54_13715	COG0243	molybdopterin cofactor binding
EYC54_13740	COG1121	(ABC) transporter
EYC54_13750	COG2733	membrane
EYC54_13755	COG2205	protein histidine kinase activity
EYC54_13755	COG5002	protein histidine kinase activity
EYC54_13755	COG0784	Response regulator, receiver
EYC54_13770	COG0477	Major facilitator Superfamily
EYC54_13790	COG2902	Dehydrogenase
EYC54_13800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EYC54_13805	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EYC54_13815	COG1609	Transcriptional regulator
EYC54_13820	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EYC54_13820	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYC54_13825	COG1105	Belongs to the carbohydrate kinase PfkB family
EYC54_13830	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EYC54_13830	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EYC54_13840	COG3501	Rhs element vgr protein
EYC54_13895	COG3039	Transposase
EYC54_13910	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EYC54_13920	COG1862	Preprotein translocase
EYC54_13985	COG0405	Gamma-glutamyltransferase
EYC54_13990	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EYC54_14010	COG0742	ribosomal rna small subunit methyltransferase
EYC54_14015	COG0326	Molecular chaperone. Has ATPase activity
EYC54_14090	COG4206	TonB-dependent receptor
EYC54_14140	COG0531	amino acid
EYC54_14155	COG0006	proline dipeptidase activity
EYC54_14165	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EYC54_14180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYC54_14185	COG3938	Belongs to the proline racemase family
EYC54_14195	COG0552	protein localization to endoplasmic reticulum
EYC54_14210	COG1194	a g-specific adenine glycosylase
EYC54_14220	COG0784	Response regulator, receiver
EYC54_14220	COG4191	Histidine kinase
EYC54_14225	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EYC54_14245	COG3040	lipid binding
EYC54_14255	COG1960	acyl-CoA dehydrogenase activity
EYC54_14305	COG0438	transferase activity, transferring glycosyl groups
EYC54_14310	COG0438	transferase activity, transferring glycosyl groups
EYC54_14355	COG0776	regulation of translation
EYC54_14365	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EYC54_14370	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EYC54_14375	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EYC54_14380	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EYC54_14415	COG0556	nucleotide-excision repair
EYC54_14420	COG4969	Belongs to the N-Me-Phe pilin family
EYC54_14460	COG1611	Belongs to the LOG family
EYC54_14475	COG2095	MarC family integral membrane protein
EYC54_14485	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EYC54_14490	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EYC54_14530	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EYC54_14545	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EYC54_14550	COG0195	Participates in both transcription termination and antitermination
EYC54_14565	COG1007	ATP synthesis coupled electron transport
EYC54_14580	COG0713	ATP synthesis coupled electron transport
EYC54_14585	COG0839	Belongs to the complex I subunit 6 family
EYC54_14595	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EYC54_14600	COG1034	ATP synthesis coupled electron transport
EYC54_14605	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EYC54_14610	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EYC54_14630	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EYC54_14650	COG1028	Short-chain dehydrogenase reductase Sdr
EYC54_14705	COG0133	tryptophan synthase activity
EYC54_14740	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EYC54_14745	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EYC54_14755	COG2890	protein-(glutamine-N5) methyltransferase activity
EYC54_14785	COG0433	COG0433 Predicted ATPase
EYC54_14810	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EYC54_14820	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EYC54_14855	COG0489	protein tyrosine kinase activity
EYC54_14860	COG3039	Transposase
EYC54_14900	COG3501	Rhs element vgr protein
EYC54_14940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYC54_14945	COG2311	Membrane
EYC54_14950	COG1047	Peptidyl-prolyl cis-trans
EYC54_14955	COG0791	NLP P60 protein
EYC54_14960	COG0791	NLP P60 protein
EYC54_14975	COG4106	trans-aconitate 2-methyltransferase activity
EYC54_14980	COG1301	dicarboxylic acid transport
EYC54_14985	COG1785	Belongs to the alkaline phosphatase family
EYC54_14990	COG0037	tRNA processing
EYC54_14995	COG1722	exodeoxyribonuclease VII activity
EYC54_15000	COG0142	geranyltranstransferase activity
EYC54_15005	COG4104	PAAR repeat-containing protein
EYC54_15020	COG0312	modulator of DNA gyrase
EYC54_15030	COG0312	modulator of DNA gyrase
EYC54_15040	COG3164	Protein of unknown function
EYC54_15045	COG1530	ribonuclease E activity
EYC54_15055	COG2968	Membrane
EYC54_15105	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EYC54_15135	COG3118	belongs to the thioredoxin family
EYC54_15205	COG1132	(ABC) transporter
EYC54_15235	COG0745	RESPONSE REGULATOR receiver
EYC54_15240	COG5002	protein histidine kinase activity
EYC54_15240	COG5000	phosphorelay sensor kinase activity
EYC54_15245	COG0475	glutathione-regulated potassium exporter activity
EYC54_15250	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EYC54_15275	COG1187	pseudouridine synthase activity
EYC54_15280	COG5002	protein histidine kinase activity
EYC54_15280	COG5001	Diguanylate cyclase
EYC54_15390	COG3039	Transposase
EYC54_15420	COG0735	belongs to the Fur family
EYC54_15460	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EYC54_15475	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EYC54_15485	COG0643	Histidine kinase
EYC54_15485	COG2198	Histidine kinase
EYC54_15495	COG0840	transmembrane signaling receptor activity
EYC54_15500	COG0835	chemotaxis
EYC54_15505	COG2199	diguanylate cyclase activity
EYC54_15505	COG2200	EAL domain
EYC54_15505	COG2202	Pas domain
EYC54_15510	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EYC54_15525	COG3501	Rhs element vgr protein
EYC54_15555	COG1515	deoxyribonuclease V activity
EYC54_15565	COG1741	Belongs to the pirin family
EYC54_15620	COG3501	Rhs element vgr protein
EYC54_15625	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EYC54_15635	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EYC54_15645	COG3501	Rhs element vgr protein
EYC54_15655	COG1741	Belongs to the pirin family
EYC54_15660	COG1966	Carbon starvation protein
EYC54_15665	COG2879	small protein
EYC54_15720	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EYC54_15725	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EYC54_15730	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
EYC54_15735	COG2080	2 iron, 2 sulfur cluster binding
EYC54_15745	COG2203	Gaf domain
EYC54_15745	COG5001	Diguanylate cyclase
EYC54_15745	COG4251	negative regulation of phosphorylation
EYC54_15745	COG3706	GGDEF domain
EYC54_15750	COG0629	single-stranded DNA binding
EYC54_15755	COG0142	geranyltranstransferase activity
EYC54_15785	COG0527	aspartate kinase activity
EYC54_15795	COG0384	phenazine biosynthesis protein PhzF
EYC54_15805	COG1764	response to oxidative stress
EYC54_15815	COG0540	Belongs to the ATCase OTCase family
EYC54_15825	COG1678	Uncharacterized ACR, COG1678
EYC54_15840	COG0519	Catalyzes the synthesis of GMP from XMP
EYC54_15870	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EYC54_15925	COG1959	2 iron, 2 sulfur cluster binding
EYC54_15930	COG0719	Fe-S assembly protein
EYC54_15935	COG0396	ATPase activity
EYC54_15940	COG0719	Fe-S assembly protein
EYC54_15945	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EYC54_15970	COG1555	photosystem II stabilization
EYC54_15975	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EYC54_15985	COG3178	'Phosphotransferase
EYC54_15990	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EYC54_16000	COG0628	permease
EYC54_16025	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EYC54_16045	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EYC54_16055	COG0271	Belongs to the BolA IbaG family
EYC54_16065	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EYC54_16075	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EYC54_16080	COG1137	ATPase activity
EYC54_16095	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYC54_16115	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYC54_16120	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EYC54_16130	COG2239	Acts as a magnesium transporter
EYC54_16140	COG1294	oxidase, subunit
EYC54_16145	COG1271	oxidase subunit
EYC54_16155	COG1113	amino acid transport
EYC54_16170	COG2197	response regulator
EYC54_16175	COG0531	amino acid
EYC54_16235	COG0789	Transcriptional regulator
EYC54_16250	COG0754	glutathionylspermidine amidase activity
EYC54_16275	COG1842	Phage shock protein A
EYC54_16340	COG3501	Rhs element vgr protein
EYC54_16405	COG3501	Rhs element vgr protein
EYC54_16460	COG3501	Rhs element vgr protein
EYC54_16530	COG3501	Rhs element vgr protein
EYC54_16535	COG3179	chitinase
EYC54_16620	COG3501	Rhs element vgr protein
EYC54_16650	COG3501	Rhs element vgr protein
EYC54_16710	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EYC54_16735	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EYC54_16750	COG2197	response regulator
EYC54_16755	COG4585	Histidine kinase
EYC54_16770	COG2894	cell division
EYC54_16775	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EYC54_16790	COG0642	Histidine kinase
EYC54_16795	COG0745	RESPONSE REGULATOR receiver
EYC54_16800	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EYC54_16810	COG2194	sulfuric ester hydrolase activity
EYC54_16840	COG3551	Protein conserved in bacteria
EYC54_16850	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EYC54_16850	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EYC54_16885	COG0753	catalase activity
EYC54_16925	COG2207	Transcriptional regulator
EYC54_16925	COG1917	Cupin 2, conserved barrel domain protein
EYC54_16935	COG1506	peptidase
EYC54_16935	COG0823	Involved in the tonB-independent uptake of proteins
EYC54_16955	COG1297	OPT oligopeptide transporter protein
EYC54_16975	COG0587	DNA-directed DNA polymerase activity
EYC54_17065	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
EYC54_17100	COG3501	Rhs element vgr protein
EYC54_17115	COG0308	aminopeptidase N
EYC54_17120	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EYC54_17130	COG0330	HflC and HflK could
EYC54_17135	COG0330	HflC and HflK could
EYC54_17220	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EYC54_17235	COG3829	transcription factor binding
EYC54_17270	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EYC54_17275	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EYC54_17290	COG1028	Short-chain dehydrogenase reductase Sdr
EYC54_17315	COG1399	metal-binding, possibly nucleic acid-binding protein
EYC54_17335	COG0714	Associated with various cellular activities
EYC54_17355	COG0537	adenosine 5'-monophosphoramidase activity
EYC54_17365	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EYC54_17385	COG0314	molybdopterin synthase activity
EYC54_17390	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EYC54_17405	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EYC54_17410	COG1234	tRNA 3'-trailer cleavage
EYC54_17420	COG0859	PFAM glycosyl transferase family 9
EYC54_17430	COG0582	viral genome integration into host DNA
EYC54_17490	COG3501	Rhs element vgr protein
EYC54_17670	COG0631	protein serine/threonine phosphatase activity
EYC54_17675	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EYC54_17710	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EYC54_17745	COG0740	serine-type endopeptidase activity
EYC54_17750	COG0544	peptidyl-prolyl cis-trans isomerase activity
EYC54_17760	COG3852	Histidine kinase
EYC54_17810	COG0473	3-isopropylmalate dehydrogenase activity
EYC54_17825	COG4783	chaperone-mediated protein folding
EYC54_17840	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EYC54_17850	COG0438	transferase activity, transferring glycosyl groups
EYC54_17855	COG0671	phosphoesterase, PA-phosphatase related
EYC54_17870	COG3291	Pkd domain containing protein
EYC54_17885	COG2833	Protein of unknown function (DUF455)
EYC54_17905	COG0285	dihydrofolate synthase activity
EYC54_17915	COG0406	alpha-ribazole phosphatase activity
EYC54_17940	COG1063	alcohol dehydrogenase
EYC54_17950	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EYC54_17955	COG4208	sulfate ABC transporter
EYC54_17960	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EYC54_17965	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EYC54_17970	COG0156	8-amino-7-oxononanoate synthase activity
EYC54_18005	COG1902	pentaerythritol trinitrate reductase activity
EYC54_18005	COG0446	pyridine nucleotide-disulphide oxidoreductase
EYC54_18025	COG0584	glycerophosphoryl diester phosphodiesterase
EYC54_18035	COG0625	glutathione transferase activity
EYC54_18045	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EYC54_18070	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
EYC54_18095	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EYC54_18105	COG0202	RNA polymerase activity
EYC54_18115	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EYC54_18120	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EYC54_18125	COG0201	protein transport
EYC54_18130	COG0200	Binds to the 23S rRNA
EYC54_18135	COG1841	ribosomal large subunit assembly
EYC54_18140	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EYC54_18145	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EYC54_18160	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EYC54_18170	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EYC54_18180	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EYC54_18185	COG0255	Belongs to the universal ribosomal protein uL29 family
EYC54_18190	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EYC54_18210	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EYC54_18215	COG0089	rRNA binding
EYC54_18255	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EYC54_18270	COG0222	ribosome binding
EYC54_18275	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EYC54_18280	COG0081	regulation of translation
EYC54_18295	COG0250	Participates in transcription elongation, termination and antitermination
EYC54_18300	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EYC54_18330	COG0012	GTP binding
EYC54_18345	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EYC54_18370	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EYC54_18385	COG0521	Mo-molybdopterin cofactor biosynthetic process
EYC54_18405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYC54_18410	COG1295	ribonuclease BN
EYC54_18440	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EYC54_18450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EYC54_18475	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EYC54_18480	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EYC54_18500	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EYC54_18550	COG2890	protein-(glutamine-N5) methyltransferase activity
EYC54_18560	COG3634	alkyl hydroperoxide reductase activity
EYC54_18565	COG0583	DNA-binding transcription factor activity
EYC54_18575	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EYC54_18580	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EYC54_18590	COG2197	response regulator
EYC54_18600	COG3706	GGDEF domain
EYC54_18600	COG0745	RESPONSE REGULATOR receiver
EYC54_18630	COG0697	spore germination
EYC54_18665	COG3386	PFAM SMP-30 Gluconolaconase
EYC54_18685	COG1024	Enoyl-CoA hydratase
EYC54_18700	COG0583	DNA-binding transcription factor activity
EYC54_18705	COG3384	dioxygenase
EYC54_18715	COG1802	Transcriptional regulator
EYC54_18735	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EYC54_18740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EYC54_18750	COG2096	Adenosyltransferase
EYC54_18755	COG0123	including yeast histone deacetylase and acetoin utilization protein
EYC54_18770	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EYC54_18790	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EYC54_18830	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EYC54_18845	COG0642	Histidine kinase
EYC54_18860	COG4181	ATPase activity
EYC54_18870	COG2175	clavaminate synthase activity
EYC54_18880	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EYC54_18885	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EYC54_18915	COG0667	Aldo Keto reductase
EYC54_18925	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EYC54_18930	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYC54_18940	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EYC54_18955	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EYC54_19000	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EYC54_19060	COG0604	alcohol dehydrogenase
EYC54_19060	COG3321	synthase
EYC54_19060	COG1028	Short-chain dehydrogenase reductase Sdr
EYC54_19075	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EYC54_19090	COG0494	nUDIX hydrolase
EYC54_19105	COG4942	peptidase
EYC54_19105	COG1388	LysM domain
EYC54_19130	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EYC54_19135	COG1181	Belongs to the D-alanine--D-alanine ligase family
EYC54_19155	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EYC54_19160	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EYC54_19175	COG3116	cell division
EYC54_19215	COG1988	membrane-bound metal-dependent
EYC54_19220	COG0277	FAD linked oxidase domain protein
EYC54_19225	COG0745	RESPONSE REGULATOR receiver
EYC54_19230	COG2205	protein histidine kinase activity
EYC54_19240	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EYC54_19245	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EYC54_19275	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EYC54_19305	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EYC54_19305	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EYC54_19315	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EYC54_19345	COG0488	(ABC) transporter
EYC54_19390	COG0745	RESPONSE REGULATOR receiver
EYC54_19395	COG2205	protein histidine kinase activity
EYC54_19495	COG1649	PFAM Uncharacterised BCR, COG1649
EYC54_19495	COG0726	polysaccharide deacetylase
EYC54_19500	COG1215	transferase activity, transferring glycosyl groups
EYC54_19510	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EYC54_19515	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EYC54_19520	COG1609	Transcriptional regulator
EYC54_19545	COG3250	beta-galactosidase activity
EYC54_19580	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EYC54_19585	COG4191	Histidine kinase
EYC54_19590	COG0784	Response regulator, receiver
EYC54_19595	COG4251	negative regulation of phosphorylation
EYC54_19600	COG2823	Periplasmic or secreted lipoprotein
EYC54_19605	COG0673	inositol 2-dehydrogenase activity
EYC54_19610	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EYC54_19645	COG1051	belongs to the nudix hydrolase family
EYC54_19645	COG1056	cytidyltransferase-related domain
EYC54_19685	COG1686	Belongs to the peptidase S11 family
EYC54_19690	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EYC54_19695	COG2951	lytic endotransglycosylase activity
EYC54_19740	COG0772	Belongs to the SEDS family
EYC54_19755	COG1792	Involved in formation and maintenance of cell shape
EYC54_19760	COG1077	Cell shape determining protein MreB Mrl
EYC54_19780	COG0308	aminopeptidase N
EYC54_19785	COG5001	Diguanylate cyclase
EYC54_19785	COG3300	MHYT domain
EYC54_19820	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EYC54_19830	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EYC54_19850	COG2832	Protein of unknown function (DUF454)
EYC54_19870	COG1505	serine-type exopeptidase activity
EYC54_19905	COG3275	phosphorelay sensor kinase activity
EYC54_19940	COG0659	secondary active sulfate transmembrane transporter activity
EYC54_19945	COG5297	Belongs to the glycosyl hydrolase family 6
EYC54_19945	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EYC54_19955	COG0840	transmembrane signaling receptor activity
EYC54_20020	COG0598	Magnesium transport protein CorA
EYC54_20030	COG1113	amino acid transport
EYC54_20040	COG5297	Belongs to the glycosyl hydrolase family 6
EYC54_20045	COG4305	rare lipoprotein A
EYC54_20050	COG0697	spore germination
EYC54_20100	COG4221	oxidoreductase activity
EYC54_20180	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EYC54_20210	COG2353	YceI-like domain
EYC54_20255	COG3386	PFAM SMP-30 Gluconolaconase
EYC54_20270	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EYC54_20275	COG3550	peptidyl-serine autophosphorylation
EYC54_20295	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EYC54_20315	COG1252	NADH dehydrogenase
EYC54_20320	COG2860	membrane
EYC54_20325	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EYC54_20335	COG3437	response regulator, receiver
EYC54_20340	COG2177	Part of the ABC transporter FtsEX involved in
EYC54_20345	COG2884	Cell division ATP-binding protein ftsE
EYC54_20355	COG3118	belongs to the thioredoxin family
EYC54_20360	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EYC54_20415	COG1473	amidohydrolase
EYC54_20425	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EYC54_20450	COG5383	Protein conserved in bacteria
EYC54_20500	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
EYC54_20505	COG3023	N-Acetylmuramoyl-L-alanine amidase
EYC54_20515	COG4948	Mandelate Racemase Muconate Lactonizing
EYC54_20540	COG0531	amino acid
EYC54_20560	COG4682	membrane
EYC54_20565	COG2133	pyrroloquinoline quinone binding
EYC54_20585	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EYC54_20595	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EYC54_20600	COG1610	YqeY-like protein
EYC54_20620	COG1295	ribonuclease BN
EYC54_20625	COG0358	DNA primase activity
EYC54_20690	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
EYC54_20705	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EYC54_20765	COG0739	heme binding
EYC54_20780	COG2211	Major facilitator Superfamily
EYC54_20785	COG0708	Exodeoxyribonuclease III
EYC54_20830	COG3501	Rhs element vgr protein
EYC54_20920	COG0740	serine-type endopeptidase activity
EYC54_20925	COG4695	Portal protein
EYC54_20930	COG1802	Transcriptional regulator
EYC54_20930	COG4626	Terminase
EYC54_21025	COG0582	viral genome integration into host DNA
EYC54_21040	COG1192	Involved in chromosome partitioning
EYC54_21045	COG1475	DNA binding
EYC54_21060	COG0463	Glycosyl transferase, family 2
EYC54_21085	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EYC54_21110	COG4221	oxidoreductase activity
EYC54_21180	COG1166	arginine decarboxylase activity
EYC54_21230	COG0606	chelatase, subunit chli
EYC54_21250	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EYC54_21295	COG1090	epimerase
EYC54_21315	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EYC54_21350	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EYC54_21360	COG1595	DNA-templated transcription, initiation
EYC54_21365	COG0753	catalase activity
EYC54_21390	COG0697	spore germination
EYC54_21410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EYC54_21415	COG0180	Tryptophanyl-tRNA synthetase
EYC54_21420	COG3237	CsbD-like
EYC54_21475	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EYC54_21475	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EYC54_21485	COG3228	Belongs to the MtfA family
EYC54_21500	COG2205	protein histidine kinase activity
EYC54_21505	COG0745	RESPONSE REGULATOR receiver
EYC54_21515	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EYC54_21545	COG1566	PFAM secretion protein HlyD family protein
EYC54_21560	COG1199	ATP-dependent helicase activity
EYC54_21600	COG0583	DNA-binding transcription factor activity
EYC54_21650	COG0625	glutathione transferase activity
EYC54_21695	COG4555	ABC transporter
EYC54_21705	COG1476	TRANSCRIPTIONal
EYC54_21725	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EYC54_21730	COG1131	(ABC) transporter
EYC54_21735	COG0842	Transport permease protein
EYC54_21745	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EYC54_21815	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EYC54_21835	COG2951	lytic endotransglycosylase activity
EYC54_21895	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EYC54_21900	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EYC54_21945	COG0183	Belongs to the thiolase family
EYC54_21965	COG2032	superoxide dismutase activity
EYC54_21970	COG2032	superoxide dismutase activity
EYC54_21975	COG2204	response regulator
EYC54_21980	COG3852	Histidine kinase
EYC54_21985	COG0004	ammonium transporteR
EYC54_21990	COG0347	Belongs to the P(II) protein family
EYC54_21995	COG0174	glutamine synthetase
EYC54_22055	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EYC54_22065	COG2062	phosphohistidine phosphatase, SixA
EYC54_22070	COG0489	protein tyrosine kinase activity
EYC54_22090	COG1396	sequence-specific DNA binding
EYC54_22095	COG3550	peptidyl-serine autophosphorylation
EYC54_22100	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
EYC54_22105	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EYC54_22120	COG0517	IMP dehydrogenase activity
EYC54_22120	COG1125	glycine betaine transport
EYC54_22135	COG1119	ATPase activity
EYC54_22145	COG1473	amidohydrolase
EYC54_22150	COG1752	Esterase of the alpha-beta hydrolase superfamily
EYC54_22155	COG4773	Receptor
EYC54_22160	COG1522	sequence-specific DNA binding
EYC54_22165	COG3186	Phenylalanine-4-hydroxylase
EYC54_22185	COG1609	Transcriptional regulator
EYC54_22210	COG0366	Alpha amylase catalytic
EYC54_22215	COG0366	Alpha amylase catalytic
EYC54_22225	COG2831	hemolysin activation secretion protein
EYC54_22265	COG3039	Transposase
EYC54_22290	COG3039	Transposase
EYC54_22500	COG3693	PFAM glycoside hydrolase, family 10
EYC54_22525	COG2211	Major facilitator Superfamily
EYC54_22570	COG2937	Belongs to the GPAT DAPAT family
EYC54_22610	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EYC54_22630	COG0210	DNA helicase
EYC54_22645	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
EYC54_22685	COG3135	benzoate transporter
EYC54_22705	COG0676	glucose-6-phosphate 1-epimerase activity
EYC54_22720	COG0730	response to heat
EYC54_22750	COG0302	gtp cyclohydrolase
EYC54_22780	COG0477	Major facilitator Superfamily
EYC54_22795	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EYC54_22845	COG0564	pseudouridine synthase activity
EYC54_22900	COG1074	ATP-dependent DNA helicase activity
EYC54_22905	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EYC54_22915	COG1116	anion transmembrane transporter activity
EYC54_22940	COG1136	(ABC) transporter
EYC54_22955	COG1127	ABC transporter
EYC54_22960	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EYC54_22965	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EYC54_22995	COG0386	Belongs to the glutathione peroxidase family
EYC54_23005	COG1322	Protein conserved in bacteria
EYC54_23020	COG0531	amino acid
EYC54_23050	COG2199	diguanylate cyclase activity
EYC54_23050	COG2203	Gaf domain
EYC54_23060	COG1929	Belongs to the glycerate kinase type-1 family
EYC54_23065	COG2271	Major facilitator Superfamily
EYC54_23080	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EYC54_23090	COG0861	Integral membrane protein TerC family
EYC54_23100	COG0584	glycerophosphoryl diester phosphodiesterase
EYC54_23110	COG0671	phosphoesterase, PA-phosphatase related
EYC54_23120	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EYC54_23125	COG0726	polysaccharide deacetylase
EYC54_23140	COG0230	Belongs to the bacterial ribosomal protein bL34 family