locus-tag	class	description
KFK26_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KFK26_00020	COG0187	DNA topoisomerase II activity
KFK26_00030	COG0501	Belongs to the peptidase M48B family
KFK26_00060	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KFK26_00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KFK26_00085	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
KFK26_00095	COG4772	TonB-dependent receptor
KFK26_00110	COG3039	Transposase
KFK26_00115	COG1304	FMN binding
KFK26_00135	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KFK26_00145	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KFK26_00240	COG2826	transposase and inactivated derivatives, IS30 family
KFK26_00265	COG3039	Transposase
KFK26_00275	COG1090	epimerase
KFK26_00285	COG0642	Histidine kinase
KFK26_00295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KFK26_00405	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KFK26_00480	COG3264	Mechanosensitive ion channel
KFK26_00480	COG1511	domain protein
KFK26_00495	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KFK26_00500	COG2354	Protein conserved in bacteria
KFK26_00505	COG1649	PFAM Uncharacterised BCR, COG1649
KFK26_00515	COG0297	glycogen (starch) synthase activity
KFK26_00525	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KFK26_00550	COG0702	epimerase
KFK26_00565	COG1858	cytochrome C peroxidase
KFK26_00630	COG0513	Belongs to the DEAD box helicase family
KFK26_00640	COG3039	Transposase
KFK26_00685	COG1136	(ABC) transporter
KFK26_00725	COG1136	(ABC) transporter
KFK26_00765	COG1272	protein, Hemolysin III
KFK26_00770	COG1205	dead DEAH box helicase
KFK26_00770	COG1111	helicase
KFK26_00830	COG0067	glutamate synthase
KFK26_00830	COG0070	glutamate synthase
KFK26_00830	COG0069	glutamate synthase activity
KFK26_00835	COG0493	'glutamate synthase
KFK26_00885	COG1609	Transcriptional regulator
KFK26_00910	COG0366	Alpha amylase catalytic
KFK26_00915	COG0366	Alpha amylase catalytic
KFK26_00975	COG0606	chelatase, subunit chli
KFK26_01020	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KFK26_01025	COG1166	arginine decarboxylase activity
KFK26_01090	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KFK26_01115	COG1028	Short-chain dehydrogenase reductase Sdr
KFK26_01140	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
KFK26_01155	COG0210	DNA helicase
KFK26_01170	COG3132	Protein of unknown function, DUF480
KFK26_01175	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
KFK26_01180	COG0284	orotidine-5'-phosphate decarboxylase activity
KFK26_01215	COG2937	Belongs to the GPAT DAPAT family
KFK26_01265	COG1752	Esterase of the alpha-beta hydrolase superfamily
KFK26_01275	COG1119	ATPase activity
KFK26_01290	COG0517	IMP dehydrogenase activity
KFK26_01290	COG1125	glycine betaine transport
KFK26_01305	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KFK26_01310	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
KFK26_01315	COG3550	peptidyl-serine autophosphorylation
KFK26_01320	COG1396	sequence-specific DNA binding
KFK26_01345	COG0489	protein tyrosine kinase activity
KFK26_01350	COG2062	phosphohistidine phosphatase, SixA
KFK26_01360	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KFK26_01405	COG1968	undecaprenyl-diphosphatase activity
KFK26_01410	COG0174	glutamine synthetase
KFK26_01415	COG0347	Belongs to the P(II) protein family
KFK26_01420	COG0004	ammonium transporteR
KFK26_01425	COG3852	Histidine kinase
KFK26_01430	COG2204	response regulator
KFK26_01435	COG2032	superoxide dismutase activity
KFK26_01440	COG2032	superoxide dismutase activity
KFK26_01475	COG1196	nuclear chromosome segregation
KFK26_01485	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KFK26_01490	COG1074	ATP-dependent DNA helicase activity
KFK26_01500	COG3549	Plasmid maintenance system killer
KFK26_01585	COG1764	response to oxidative stress
KFK26_01590	COG1846	Transcriptional regulator
KFK26_01675	COG2211	Major facilitator Superfamily
KFK26_01695	COG3693	PFAM glycoside hydrolase, family 10
KFK26_01720	COG0246	Mannitol dehydrogenase
KFK26_01725	COG1472	Belongs to the glycosyl hydrolase 3 family
KFK26_01735	COG4948	Mandelate Racemase Muconate Lactonizing
KFK26_01745	COG3661	Belongs to the glycosyl hydrolase 67 family
KFK26_01760	COG0037	tRNA processing
KFK26_01765	COG2974	May be involved in recombination
KFK26_01790	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KFK26_01800	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KFK26_01810	COG0805	protein transport
KFK26_01820	COG0519	Catalyzes the synthesis of GMP from XMP
KFK26_01820	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KFK26_01835	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KFK26_01840	COG0752	glycyl-tRNA synthetase alpha subunit
KFK26_01850	COG0457	Tetratricopeptide repeat
KFK26_01855	COG4771	TonB-dependent receptor
KFK26_01870	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KFK26_01890	COG0523	cobalamin synthesis protein
KFK26_01945	COG1960	acyl-CoA dehydrogenase activity
KFK26_01950	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KFK26_01955	COG4770	biotin carboxylase activity
KFK26_02015	COG2072	flavoprotein involved in K transport
KFK26_02035	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KFK26_02085	COG0084	hydrolase, TatD family'
KFK26_02100	COG0583	DNA-binding transcription factor activity
KFK26_02105	COG2814	Major facilitator Superfamily
KFK26_02115	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KFK26_02120	COG1902	pentaerythritol trinitrate reductase activity
KFK26_02150	COG0745	RESPONSE REGULATOR receiver
KFK26_02170	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KFK26_02175	COG0583	DNA-binding transcription factor activity
KFK26_02205	COG0702	epimerase
KFK26_02210	COG1733	regulation of RNA biosynthetic process
KFK26_02260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KFK26_02275	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KFK26_02310	COG2911	Protein conserved in bacteria
KFK26_02315	COG0729	surface antigen
KFK26_02330	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KFK26_02335	COG3118	belongs to the thioredoxin family
KFK26_02345	COG2884	Cell division ATP-binding protein ftsE
KFK26_02350	COG2177	Part of the ABC transporter FtsEX involved in
KFK26_02355	COG2201	protein-glutamate methylesterase activity
KFK26_02360	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KFK26_02365	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KFK26_02375	COG1252	NADH dehydrogenase
KFK26_02400	COG0459	protein refolding
KFK26_02410	COG4771	TonB-dependent receptor
KFK26_02425	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KFK26_02470	COG3386	PFAM SMP-30 Gluconolaconase
KFK26_02485	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KFK26_02520	COG0778	Nitroreductase
KFK26_02525	COG2353	YceI-like domain
KFK26_02615	COG0408	coproporphyrinogen oxidase activity
KFK26_02625	COG3039	Transposase
KFK26_02645	COG0129	dihydroxy-acid dehydratase activity
KFK26_02655	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KFK26_02685	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KFK26_02690	COG0318	PFAM AMP-dependent synthetase and ligase
KFK26_02695	COG0727	PFAM Uncharacterised protein family (UPF0153)
KFK26_02700	COG0596	Alpha beta hydrolase
KFK26_02715	COG3177	Filamentation induced by cAMP protein fic
KFK26_02720	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KFK26_02735	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KFK26_02760	COG4191	Histidine kinase
KFK26_02765	COG0028	Belongs to the TPP enzyme family
KFK26_02780	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
KFK26_02785	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KFK26_02820	COG5383	Protein conserved in bacteria
KFK26_02830	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KFK26_02835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFK26_02845	COG1473	amidohydrolase
KFK26_02855	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KFK26_02855	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KFK26_02915	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KFK26_02920	COG0134	indole-3-glycerol-phosphate synthase activity
KFK26_02930	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KFK26_02935	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KFK26_02945	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
KFK26_02950	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KFK26_02955	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KFK26_03005	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KFK26_03020	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
KFK26_03085	COG3039	Transposase
KFK26_03110	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KFK26_03130	COG0534	Mate efflux family protein
KFK26_03135	COG0616	signal peptide processing
KFK26_03145	COG1028	Short-chain dehydrogenase reductase Sdr
KFK26_03160	COG0009	L-threonylcarbamoyladenylate synthase
KFK26_03165	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KFK26_03165	COG1754	DNA topoisomerase type I activity
KFK26_03180	COG2922	Belongs to the Smg family
KFK26_03185	COG0758	DNA mediated transformation
KFK26_03190	COG1652	LysM domain
KFK26_03195	COG0242	peptide deformylase activity
KFK26_03200	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KFK26_03205	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KFK26_03205	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KFK26_03255	COG1560	Kdo2-lipid A biosynthetic process
KFK26_03265	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KFK26_03405	COG0358	DNA primase activity
KFK26_03410	COG1295	ribonuclease BN
KFK26_03425	COG1610	YqeY-like protein
KFK26_03435	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KFK26_03440	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KFK26_03475	COG2133	pyrroloquinoline quinone binding
KFK26_03480	COG4682	membrane
KFK26_03510	COG0531	amino acid
KFK26_03540	COG4948	Mandelate Racemase Muconate Lactonizing
KFK26_03550	COG3023	N-Acetylmuramoyl-L-alanine amidase
KFK26_03555	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
KFK26_03625	COG0183	Belongs to the thiolase family
KFK26_03660	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KFK26_03670	COG3483	tryptophan 2,3-dioxygenase activity
KFK26_03675	COG3104	oligopeptide transport
KFK26_03695	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
KFK26_03705	COG1320	monovalent cation:proton antiporter activity
KFK26_03710	COG2212	antiporter activity
KFK26_03720	COG0651	ATP synthesis coupled electron transport
KFK26_03725	COG1006	Multisubunit Na H antiporter MnhC subunit
KFK26_03730	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KFK26_03730	COG2111	Na H antiporter
KFK26_03775	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KFK26_03785	COG0456	acetyltransferase
KFK26_03815	COG4221	oxidoreductase activity
KFK26_03875	COG0697	spore germination
KFK26_03880	COG4305	rare lipoprotein A
KFK26_03885	COG5297	Belongs to the glycosyl hydrolase family 6
KFK26_03895	COG1113	amino acid transport
KFK26_03905	COG0598	Magnesium transport protein CorA
KFK26_03925	COG3039	Transposase
KFK26_03985	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KFK26_03985	COG5297	Belongs to the glycosyl hydrolase family 6
KFK26_03990	COG0659	secondary active sulfate transmembrane transporter activity
KFK26_04035	COG3275	phosphorelay sensor kinase activity
KFK26_04045	COG0181	hydroxymethylbilane synthase activity
KFK26_04070	COG1505	serine-type exopeptidase activity
KFK26_04085	COG0436	Aminotransferase
KFK26_04115	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KFK26_04145	COG0308	aminopeptidase N
KFK26_04150	COG2199	diguanylate cyclase activity
KFK26_04195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KFK26_04200	COG1077	Cell shape determining protein MreB Mrl
KFK26_04205	COG1792	Involved in formation and maintenance of cell shape
KFK26_04220	COG0772	Belongs to the SEDS family
KFK26_04255	COG1388	LysM domain
KFK26_04255	COG3409	Peptidoglycan-binding domain 1 protein
KFK26_04255	COG5632	N-Acetylmuramoyl-L-alanine amidase
KFK26_04275	COG2951	lytic endotransglycosylase activity
KFK26_04280	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KFK26_04285	COG1686	Belongs to the peptidase S11 family
KFK26_04300	COG2921	Belongs to the UPF0250 family
KFK26_04325	COG1056	cytidyltransferase-related domain
KFK26_04325	COG1051	belongs to the nudix hydrolase family
KFK26_04360	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KFK26_04365	COG0673	inositol 2-dehydrogenase activity
KFK26_04370	COG2823	Periplasmic or secreted lipoprotein
KFK26_04375	COG4251	negative regulation of phosphorylation
KFK26_04380	COG0784	Response regulator, receiver
KFK26_04385	COG4191	Histidine kinase
KFK26_04390	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KFK26_04440	COG3250	beta-galactosidase activity
KFK26_04455	COG2188	Transcriptional regulator
KFK26_04465	COG1609	Transcriptional regulator
KFK26_04470	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KFK26_04475	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KFK26_04485	COG1215	transferase activity, transferring glycosyl groups
KFK26_04490	COG1649	PFAM Uncharacterised BCR, COG1649
KFK26_04490	COG0726	polysaccharide deacetylase
KFK26_04600	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KFK26_04610	COG3039	Transposase
KFK26_04645	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KFK26_04665	COG2205	protein histidine kinase activity
KFK26_04695	COG2205	protein histidine kinase activity
KFK26_04745	COG0488	(ABC) transporter
KFK26_04765	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KFK26_04785	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KFK26_04785	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KFK26_04805	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KFK26_04810	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KFK26_04815	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KFK26_04835	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KFK26_04840	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
KFK26_04850	COG2205	protein histidine kinase activity
KFK26_04855	COG0745	RESPONSE REGULATOR receiver
KFK26_04860	COG0277	FAD linked oxidase domain protein
KFK26_04865	COG1988	membrane-bound metal-dependent
KFK26_04870	COG0792	nuclease activity
KFK26_04905	COG0275	rRNA processing
KFK26_04910	COG3116	cell division
KFK26_04925	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KFK26_04930	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KFK26_04945	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KFK26_04950	COG1181	Belongs to the D-alanine--D-alanine ligase family
KFK26_04955	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KFK26_04970	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
KFK26_04980	COG4942	peptidase
KFK26_04980	COG1388	LysM domain
KFK26_04985	COG0653	protein targeting
KFK26_04995	COG0494	nUDIX hydrolase
KFK26_05010	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KFK26_05020	COG0604	alcohol dehydrogenase
KFK26_05020	COG1028	Short-chain dehydrogenase reductase Sdr
KFK26_05020	COG3321	synthase
KFK26_05065	COG2226	methyltransferase
KFK26_05070	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KFK26_05115	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KFK26_05130	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KFK26_05140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KFK26_05145	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KFK26_05155	COG3039	Transposase
KFK26_05165	COG0667	Aldo Keto reductase
KFK26_05215	COG2175	clavaminate synthase activity
KFK26_05225	COG4181	ATPase activity
KFK26_05240	COG0642	Histidine kinase
KFK26_05265	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KFK26_05285	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KFK26_05305	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KFK26_05310	COG2967	ApaG domain
KFK26_05315	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KFK26_05325	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KFK26_05340	COG0123	including yeast histone deacetylase and acetoin utilization protein
KFK26_05345	COG2096	Adenosyltransferase
KFK26_05355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KFK26_05360	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KFK26_05400	COG0583	DNA-binding transcription factor activity
KFK26_05405	COG0318	PFAM AMP-dependent synthetase and ligase
KFK26_05415	COG1024	Enoyl-CoA hydratase
KFK26_05435	COG3386	PFAM SMP-30 Gluconolaconase
KFK26_05445	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
KFK26_05525	COG3039	Transposase
KFK26_05550	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KFK26_05575	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KFK26_05580	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KFK26_05585	COG0583	DNA-binding transcription factor activity
KFK26_05590	COG3634	alkyl hydroperoxide reductase activity
KFK26_05600	COG2890	protein-(glutamine-N5) methyltransferase activity
KFK26_05640	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KFK26_05640	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KFK26_05655	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
KFK26_05680	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
KFK26_05705	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KFK26_05715	COG1404	Belongs to the peptidase S8 family
KFK26_05720	COG1404	Belongs to the peptidase S8 family
KFK26_05725	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KFK26_05755	COG1295	ribonuclease BN
KFK26_05760	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KFK26_05780	COG0521	Mo-molybdopterin cofactor biosynthetic process
KFK26_05790	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KFK26_05795	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KFK26_05805	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
KFK26_05820	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KFK26_05830	COG0193	aminoacyl-tRNA hydrolase activity
KFK26_05835	COG0012	GTP binding
KFK26_05865	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KFK26_05870	COG0250	Participates in transcription elongation, termination and antitermination
KFK26_05875	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KFK26_05880	COG0081	regulation of translation
KFK26_05885	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KFK26_05890	COG0222	ribosome binding
KFK26_05895	COG0085	RNA polymerase activity
KFK26_05900	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KFK26_05905	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KFK26_05910	COG0049	tRNA binding
KFK26_05930	COG0051	transcription antitermination factor activity, RNA binding
KFK26_05935	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KFK26_05940	COG0088	Forms part of the polypeptide exit tunnel
KFK26_05945	COG0089	rRNA binding
KFK26_05960	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KFK26_05970	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KFK26_05975	COG0255	Belongs to the universal ribosomal protein uL29 family
KFK26_05980	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KFK26_05985	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KFK26_05990	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KFK26_05995	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KFK26_06015	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KFK26_06025	COG1841	ribosomal large subunit assembly
KFK26_06035	COG0201	protein transport
KFK26_06045	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KFK26_06050	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KFK26_06060	COG0203	ribosomal protein L17
KFK26_06120	COG3551	Protein conserved in bacteria
KFK26_06150	COG2194	sulfuric ester hydrolase activity
KFK26_06160	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KFK26_06165	COG0745	RESPONSE REGULATOR receiver
KFK26_06170	COG0642	Histidine kinase
KFK26_06180	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
KFK26_06185	COG2894	cell division
KFK26_06200	COG4585	Histidine kinase
KFK26_06205	COG2197	response regulator
KFK26_06220	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KFK26_06245	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KFK26_06315	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KFK26_06325	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KFK26_06360	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KFK26_06390	COG3039	Transposase
KFK26_06410	COG3039	Transposase
KFK26_06430	COG3039	Transposase
KFK26_06450	COG1741	Belongs to the pirin family
KFK26_06460	COG1515	deoxyribonuclease V activity
KFK26_06465	COG0588	phosphoglycerate mutase activity
KFK26_06480	COG3590	peptidase
KFK26_06495	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KFK26_06500	COG2199	diguanylate cyclase activity
KFK26_06500	COG2200	EAL domain
KFK26_06500	COG2202	Pas domain
KFK26_06505	COG0835	chemotaxis
KFK26_06510	COG0840	transmembrane signaling receptor activity
KFK26_06515	COG2198	Histidine kinase
KFK26_06515	COG0643	Histidine kinase
KFK26_06520	COG3039	Transposase
KFK26_06540	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KFK26_06550	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KFK26_06555	COG2205	protein histidine kinase activity
KFK26_06585	COG3039	Transposase
KFK26_06645	COG3039	Transposase
KFK26_06670	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KFK26_06675	COG0735	belongs to the Fur family
KFK26_06735	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KFK26_06740	COG0084	hydrolase, TatD family'
KFK26_06755	COG1960	acyl-CoA dehydrogenase activity
KFK26_06770	COG0367	asparagine synthase
KFK26_06780	COG0305	Participates in initiation and elongation during chromosome replication
KFK26_06785	COG0415	Belongs to the DNA photolyase family
KFK26_06800	COG1028	Short-chain dehydrogenase reductase Sdr
KFK26_06900	COG5001	Diguanylate cyclase
KFK26_06900	COG5002	protein histidine kinase activity
KFK26_06905	COG1187	pseudouridine synthase activity
KFK26_06925	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KFK26_06935	COG0475	glutathione-regulated potassium exporter activity
KFK26_06940	COG5002	protein histidine kinase activity
KFK26_06940	COG5000	phosphorelay sensor kinase activity
KFK26_06945	COG0745	RESPONSE REGULATOR receiver
KFK26_06975	COG1132	(ABC) transporter
KFK26_07015	COG3209	COG3209 Rhs family protein
KFK26_07025	COG3039	Transposase
KFK26_07060	COG3039	Transposase
KFK26_07070	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KFK26_07080	COG4969	Belongs to the N-Me-Phe pilin family
KFK26_07085	COG2194	sulfuric ester hydrolase activity
KFK26_07105	COG2184	nucleotidyltransferase activity
KFK26_07130	COG0045	succinate-CoA ligase (ADP-forming) activity
KFK26_07135	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KFK26_07145	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KFK26_07145	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KFK26_07150	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KFK26_07155	COG0564	pseudouridine synthase activity
KFK26_07180	COG3387	PFAM Glycoside hydrolase 15-related
KFK26_07185	COG1877	trehalose-phosphatase activity
KFK26_07220	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
KFK26_07235	COG1595	DNA-templated transcription, initiation
KFK26_07245	COG1946	Acyl-CoA thioesterase
KFK26_07260	COG0824	Thioesterase
KFK26_07265	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KFK26_07275	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KFK26_07280	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KFK26_07285	COG0268	Binds directly to 16S ribosomal RNA
KFK26_07290	COG0728	peptidoglycan biosynthetic process
KFK26_07295	COG0196	riboflavin kinase activity
KFK26_07305	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KFK26_07310	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KFK26_07325	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KFK26_07330	COG1845	cytochrome c oxidase, subunit III
KFK26_07335	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KFK26_07375	COG3209	COG3209 Rhs family protein
KFK26_07410	COG3039	Transposase
KFK26_07445	COG3039	Transposase
KFK26_07505	COG3039	Transposase
KFK26_07605	COG0631	protein serine/threonine phosphatase activity
KFK26_07610	COG0515	serine threonine protein kinase
KFK26_07640	COG1858	cytochrome C peroxidase
KFK26_07695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFK26_07700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KFK26_07720	COG2201	protein-glutamate methylesterase activity
KFK26_07750	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KFK26_07770	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KFK26_07785	COG1595	DNA-templated transcription, initiation
KFK26_07835	COG2244	polysaccharide biosynthetic process
KFK26_07865	COG2264	protein methyltransferase activity
KFK26_07875	COG0438	transferase activity, transferring glycosyl groups
KFK26_07890	COG1136	(ABC) transporter
KFK26_07895	COG1132	(ABC) transporter
KFK26_07905	COG0477	Major facilitator Superfamily
KFK26_07915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KFK26_07930	COG1253	flavin adenine dinucleotide binding
KFK26_07940	COG0306	phosphate transporter
KFK26_07970	COG0504	CTP synthase activity
KFK26_07975	COG2877	3-deoxy-8-phosphooctulonate synthase activity
KFK26_07985	COG0148	phosphopyruvate hydratase activity
KFK26_07990	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KFK26_07995	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KFK26_08005	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KFK26_08015	COG2840	Smr protein MutS2
KFK26_08020	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KFK26_08025	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KFK26_08030	COG1238	metal cluster binding
KFK26_08045	COG1534	Rna-binding protein
KFK26_08050	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KFK26_08060	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KFK26_08065	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KFK26_08075	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KFK26_08080	COG1546	Belongs to the CinA family
KFK26_08095	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KFK26_08100	COG2137	regulation of response to DNA damage stimulus
KFK26_08105	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KFK26_08110	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KFK26_08130	COG0305	Participates in initiation and elongation during chromosome replication
KFK26_08135	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KFK26_08160	COG1741	Belongs to the pirin family
KFK26_08165	COG0583	DNA-binding transcription factor activity
KFK26_08195	COG0351	phosphomethylpyrimidine kinase
KFK26_08205	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KFK26_08210	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KFK26_08225	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KFK26_08235	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KFK26_08240	COG3734	2-keto-3-deoxy-galactonokinase
KFK26_08250	COG4948	Mandelate Racemase Muconate Lactonizing
KFK26_08255	COG0800	Aldolase
KFK26_08270	COG1501	Belongs to the glycosyl hydrolase 31 family
KFK26_08280	COG1070	Carbohydrate kinase
KFK26_08290	COG0477	Major facilitator Superfamily
KFK26_08310	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KFK26_08360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KFK26_08365	COG2258	MOSC domain
KFK26_08375	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KFK26_08380	COG0505	Belongs to the CarA family
KFK26_08390	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KFK26_08395	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KFK26_08405	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KFK26_08460	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KFK26_08470	COG0784	Response regulator, receiver
KFK26_08470	COG2198	Histidine kinase
KFK26_08470	COG2205	protein histidine kinase activity
KFK26_08475	COG1024	Enoyl-CoA hydratase
KFK26_08480	COG0318	PFAM AMP-dependent synthetase and ligase
KFK26_08510	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KFK26_08540	COG0840	transmembrane signaling receptor activity
KFK26_08560	COG0835	chemotaxis
KFK26_08580	COG0840	transmembrane signaling receptor activity
KFK26_08585	COG0840	transmembrane signaling receptor activity
KFK26_08590	COG0840	transmembrane signaling receptor activity
KFK26_08595	COG0840	transmembrane signaling receptor activity
KFK26_08605	COG0840	transmembrane signaling receptor activity
KFK26_08615	COG0840	transmembrane signaling receptor activity
KFK26_08625	COG0840	transmembrane signaling receptor activity
KFK26_08645	COG0745	RESPONSE REGULATOR receiver
KFK26_08655	COG0835	chemotaxis
KFK26_08665	COG1360	Flagellar Motor Protein
KFK26_08670	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KFK26_08690	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KFK26_08700	COG4771	TonB-dependent receptor
KFK26_08820	COG3039	Transposase
KFK26_08830	COG3039	Transposase
KFK26_08845	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KFK26_08845	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KFK26_08850	COG1105	Belongs to the carbohydrate kinase PfkB family
KFK26_08855	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KFK26_08855	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KFK26_08860	COG1609	Transcriptional regulator
KFK26_08885	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KFK26_08890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFK26_08900	COG2902	Dehydrogenase
KFK26_08905	COG3039	Transposase
KFK26_08915	COG0784	Response regulator, receiver
KFK26_08915	COG2205	protein histidine kinase activity
KFK26_08915	COG5002	protein histidine kinase activity
KFK26_08920	COG2733	membrane
KFK26_08930	COG1121	(ABC) transporter
KFK26_08935	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KFK26_08940	COG2223	nitrite transmembrane transporter activity
KFK26_08950	COG0243	molybdopterin cofactor binding
KFK26_08960	COG0477	Major facilitator Superfamily
KFK26_08970	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KFK26_08975	COG0174	glutamine synthetase
KFK26_09010	COG3842	ATPase activity
KFK26_09020	COG1177	transmembrane transport
KFK26_09030	COG1012	belongs to the aldehyde dehydrogenase family
KFK26_09045	COG4535	Mg2 and Co2 transporter CorC
KFK26_09065	COG1702	phosphate starvation-inducible protein PhoH
KFK26_09070	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KFK26_09090	COG0741	lytic transglycosylase activity
KFK26_09095	COG0723	plastoquinol--plastocyanin reductase activity
KFK26_09100	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KFK26_09105	COG2857	Cytochrome c1
KFK26_09110	COG0625	glutathione transferase activity
KFK26_09115	COG2969	positive regulation of protein catabolic process
KFK26_09150	COG3328	transposase activity
KFK26_09230	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KFK26_09245	COG1570	exodeoxyribonuclease VII activity
KFK26_09250	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KFK26_09255	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KFK26_09255	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KFK26_09260	COG0802	atpase or kinase
KFK26_09265	COG0860	N-Acetylmuramoyl-L-alanine amidase
KFK26_09270	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KFK26_09290	COG1028	Short-chain dehydrogenase reductase Sdr
KFK26_09300	COG0501	Belongs to the peptidase M48B family
KFK26_09310	COG2081	HI0933 family
KFK26_09315	COG4681	YaeQ
KFK26_09320	COG1671	Belongs to the UPF0178 family
KFK26_09330	COG0625	glutathione transferase activity
KFK26_09340	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KFK26_09345	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KFK26_09350	COG0513	Belongs to the DEAD box helicase family
KFK26_09355	COG0488	(ABC) transporter
KFK26_09375	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KFK26_09380	COG0483	inositol monophosphate 1-phosphatase activity
KFK26_09395	COG5001	Diguanylate cyclase
KFK26_09395	COG3300	MHYT domain
KFK26_09400	COG1509	lysine 2,3-aminomutase activity
KFK26_09415	COG0402	S-adenosylhomocysteine deaminase activity
KFK26_09420	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KFK26_09445	COG4677	pectinesterase activity
KFK26_09465	COG3039	Transposase
KFK26_09495	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KFK26_09520	COG2166	iron-sulfur cluster assembly
KFK26_09535	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KFK26_09540	COG0137	argininosuccinate synthase activity
KFK26_09550	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KFK26_09555	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KFK26_09570	COG0165	Argininosuccinate lyase
KFK26_09590	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KFK26_09620	COG1271	oxidase subunit
KFK26_09630	COG4988	ABC transporter
KFK26_09635	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KFK26_09740	COG0742	ribosomal rna small subunit methyltransferase
KFK26_09745	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KFK26_09755	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KFK26_09760	COG0405	Gamma-glutamyltransferase
KFK26_09825	COG3039	Transposase
KFK26_09865	COG0343	queuine tRNA-ribosyltransferase activity
KFK26_09870	COG1862	Preprotein translocase
KFK26_09875	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KFK26_09880	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KFK26_09910	COG3328	transposase activity
KFK26_09925	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KFK26_09935	COG0704	Plays a role in the regulation of phosphate uptake
KFK26_09950	COG0573	inorganic phosphate transmembrane transporter activity
KFK26_09955	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KFK26_09990	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KFK26_10000	COG1024	Enoyl-CoA hydratase
KFK26_10015	COG0494	nUDIX hydrolase
KFK26_10060	COG0116	Belongs to the methyltransferase superfamily
KFK26_10060	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KFK26_10085	COG0667	Aldo Keto reductase
KFK26_10095	COG2925	Exonuclease
KFK26_10105	COG3844	kynureninase activity
KFK26_10130	COG0288	reversible hydration of carbon dioxide
KFK26_10160	COG0316	Belongs to the HesB IscA family
KFK26_10165	COG0360	Binds together with S18 to 16S ribosomal RNA
KFK26_10175	COG0359	binds to the 23S rRNA
KFK26_10185	COG3115	cell septum assembly
KFK26_10205	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
KFK26_10220	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KFK26_10245	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KFK26_10255	COG2986	histidine ammonia-lyase
KFK26_10260	COG1228	amidohydrolase
KFK26_10300	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KFK26_10305	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KFK26_10310	COG1605	Chorismate mutase
KFK26_10310	COG0077	Prephenate dehydratase
KFK26_10315	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KFK26_10345	COG4566	intracellular signal transduction
KFK26_10395	COG0860	N-Acetylmuramoyl-L-alanine amidase
KFK26_10400	COG1469	GTP cyclohydrolase I activity
KFK26_10410	COG0617	tRNA 3'-terminal CCA addition
KFK26_10420	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KFK26_10425	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KFK26_10435	COG0166	Belongs to the GPI family
KFK26_10455	COG1472	Belongs to the glycosyl hydrolase 3 family
KFK26_10470	COG4251	negative regulation of phosphorylation
KFK26_10470	COG2203	Gaf domain
KFK26_10470	COG3706	GGDEF domain
KFK26_10470	COG5001	Diguanylate cyclase
KFK26_10555	COG0386	Belongs to the glutathione peroxidase family
KFK26_10630	COG1247	-acetyltransferase
KFK26_10650	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KFK26_10675	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KFK26_10690	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KFK26_10695	COG1393	Belongs to the ArsC family
KFK26_10700	COG0431	NADPH-dependent FMN reductase
KFK26_10705	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KFK26_10710	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KFK26_10735	COG0784	Response regulator, receiver
KFK26_10735	COG2205	protein histidine kinase activity
KFK26_10735	COG5002	protein histidine kinase activity
KFK26_10775	COG0800	Aldolase
KFK26_10780	COG0129	dihydroxy-acid dehydratase activity
KFK26_10785	COG0363	glucosamine-6-phosphate deaminase activity
KFK26_10795	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KFK26_10810	COG0354	folic acid binding
KFK26_10825	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KFK26_10840	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KFK26_10855	COG4591	ABC-type transport system involved in lipoprotein release permease component
KFK26_10880	COG0811	peptide transport
KFK26_10895	COG1663	tetraacyldisaccharide 4'-kinase activity
KFK26_10905	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KFK26_10915	COG0322	excinuclease ABC activity
KFK26_10950	COG3328	transposase activity
KFK26_10970	COG2801	Transposase and inactivated derivatives
KFK26_10980	COG2201	protein-glutamate methylesterase activity
KFK26_11010	COG0653	protein targeting
KFK26_11145	COG0140	phosphoribosyl-ATP diphosphatase activity
KFK26_11145	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KFK26_11155	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KFK26_11165	COG0131	Imidazoleglycerol-phosphate dehydratase
KFK26_11165	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KFK26_11180	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KFK26_11210	COG0124	histidyl-tRNA synthetase
KFK26_11225	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KFK26_11270	COG1012	belongs to the aldehyde dehydrogenase family
KFK26_11285	COG0167	dihydroorotate dehydrogenase activity
KFK26_11290	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KFK26_11295	COG0697	spore germination
KFK26_11300	COG1794	racemase activity, acting on amino acids and derivatives
KFK26_11320	COG0671	phosphoesterase, PA-phosphatase related
KFK26_11335	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
KFK26_11350	COG2183	response to ionizing radiation
KFK26_11360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KFK26_11360	COG0723	plastoquinol--plastocyanin reductase activity
KFK26_11375	COG3243	poly(R)-hydroxyalkanoic acid synthase
KFK26_11385	COG1183	phosphatidylcholine synthase activity
KFK26_11390	COG1028	Short-chain dehydrogenase reductase Sdr
KFK26_11405	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KFK26_11415	COG0668	transmembrane transport
KFK26_11435	COG1914	H( )-stimulated, divalent metal cation uptake system
KFK26_11485	COG0583	DNA-binding transcription factor activity
KFK26_11490	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KFK26_11495	COG3002	Belongs to the UPF0753 family
KFK26_11500	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KFK26_11500	COG0519	Catalyzes the synthesis of GMP from XMP
KFK26_11510	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KFK26_11530	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KFK26_11540	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KFK26_11545	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
KFK26_11555	COG0776	regulation of translation
KFK26_11560	COG0539	negative regulation of cytoplasmic translation
KFK26_11565	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KFK26_11580	COG2957	Belongs to the agmatine deiminase family
KFK26_11590	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KFK26_11615	COG0395	ABC-type sugar transport system, permease component
KFK26_11620	COG1175	transmembrane transport
KFK26_11650	COG2350	Protein conserved in bacteria
KFK26_11655	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KFK26_11660	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KFK26_11665	COG1187	pseudouridine synthase activity
KFK26_11690	COG0436	Aminotransferase
KFK26_11755	COG0277	FAD linked oxidase domain protein
KFK26_11760	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KFK26_11770	COG0531	amino acid
KFK26_11775	COG0531	amino acid
KFK26_11780	COG0235	Class ii aldolase
KFK26_11785	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KFK26_11790	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
KFK26_11825	COG3039	Transposase
KFK26_11835	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KFK26_11910	COG0303	'Molybdopterin
KFK26_11920	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KFK26_11930	COG1426	Protein conserved in bacteria
KFK26_11940	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KFK26_11955	COG1250	3-hydroxyacyl-CoA dehydrogenase
KFK26_11955	COG1024	Enoyl-CoA hydratase
KFK26_11960	COG0183	Belongs to the thiolase family
KFK26_11965	COG0038	chloride channel
KFK26_11985	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KFK26_12005	COG1674	ftsk spoiiie
KFK26_12010	COG0492	ferredoxin-NADP+ reductase activity
KFK26_12035	COG0542	response to heat
KFK26_12050	COG0482	sulfurtransferase activity
KFK26_12075	COG5001	Diguanylate cyclase
KFK26_12080	COG4585	Histidine kinase
KFK26_12090	COG5002	protein histidine kinase activity
KFK26_12110	COG0784	Response regulator, receiver
KFK26_12110	COG0835	chemotaxis
KFK26_12120	COG1558	bacterial-type flagellum-dependent cell motility
KFK26_12125	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
KFK26_12135	COG4787	bacterial-type flagellum-dependent cell motility
KFK26_12170	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KFK26_12175	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KFK26_12205	COG2201	protein-glutamate methylesterase activity
KFK26_12225	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KFK26_12235	COG1028	Short-chain dehydrogenase reductase Sdr
KFK26_12265	COG1677	Flagellar hook-basal body complex protein FliE
KFK26_12315	COG3190	flagellar
KFK26_12330	COG1684	flagellar biosynthetic protein fliR
KFK26_12385	COG0643	Histidine kinase
KFK26_12385	COG0784	Response regulator, receiver
KFK26_12385	COG2198	Histidine kinase
KFK26_12500	COG0583	DNA-binding transcription factor activity
KFK26_12510	COG3039	Transposase
KFK26_12590	COG1278	Cold shock
KFK26_12600	COG3328	transposase activity
KFK26_12630	COG3039	Transposase
KFK26_12640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KFK26_12655	COG0557	exoribonuclease II activity
KFK26_12680	COG1960	acyl-CoA dehydrogenase activity
KFK26_12685	COG2226	methyltransferase
KFK26_12690	COG0646	methionine synthase
KFK26_12690	COG1410	methionine synthase
KFK26_12695	COG1410	methionine synthase
KFK26_12695	COG0646	methionine synthase
KFK26_12705	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KFK26_12715	COG1609	Transcriptional regulator
KFK26_12730	COG2900	Belongs to the SlyX family
KFK26_12745	COG0386	Belongs to the glutathione peroxidase family
KFK26_12755	COG1725	Transcriptional regulator
KFK26_12760	COG1131	(ABC) transporter
KFK26_12835	COG2850	peptidyl-arginine hydroxylation
KFK26_12870	COG1132	(ABC) transporter
KFK26_12885	COG0583	DNA-binding transcription factor activity
KFK26_12900	COG1605	Chorismate mutase
KFK26_12900	COG0287	Prephenate dehydrogenase
KFK26_12905	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
KFK26_12910	COG0484	heat shock protein binding
KFK26_12915	COG0443	Heat shock 70 kDa protein
KFK26_12920	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KFK26_12930	COG0497	DNA recombination
KFK26_12940	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KFK26_12945	COG2914	Belongs to the UPF0125 (RnfH) family
KFK26_12955	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KFK26_12970	COG1960	acyl-CoA dehydrogenase activity
KFK26_12980	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KFK26_13025	COG2814	Major facilitator Superfamily
KFK26_13030	COG1566	PFAM secretion protein HlyD family protein
KFK26_13045	COG2207	Transcriptional regulator
KFK26_13070	COG4774	siderophore transport
KFK26_13080	COG0367	asparagine synthase
KFK26_13085	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KFK26_13095	COG1393	Belongs to the ArsC family
KFK26_13155	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KFK26_13170	COG0233	cytoplasmic translational termination
KFK26_13180	COG0575	Belongs to the CDS family
KFK26_13185	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KFK26_13190	COG0750	zinc metalloprotease
KFK26_13210	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KFK26_13215	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KFK26_13235	COG0825	malonyl-CoA metabolic process
KFK26_13245	COG4771	TonB-dependent receptor
KFK26_13250	COG1131	(ABC) transporter
KFK26_13275	COG1981	membrane
KFK26_13320	COG0529	Catalyzes the synthesis of activated sulfate
KFK26_13320	COG2895	sulfate adenylyltransferase (ATP) activity
KFK26_13360	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KFK26_13380	COG2040	homocysteine
KFK26_13385	COG0833	amino acid
KFK26_13405	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KFK26_13405	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KFK26_13415	COG2878	Part of a membrane complex involved in electron transport
KFK26_13430	COG1595	DNA-templated transcription, initiation
KFK26_13455	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KFK26_13470	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KFK26_13475	COG0251	oxidation-reduction process
KFK26_13485	COG0392	lysyltransferase activity
KFK26_13485	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KFK26_13520	COG2814	Major facilitator Superfamily
KFK26_13525	COG1902	pentaerythritol trinitrate reductase activity
KFK26_13535	COG2824	Alkylphosphonate utilization operon protein PhnA
KFK26_13550	COG1047	Peptidyl-prolyl cis-trans
KFK26_13585	COG3039	Transposase
KFK26_13590	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KFK26_13605	COG1451	nucleotide metabolic process
KFK26_13625	COG0183	Belongs to the thiolase family
KFK26_13655	COG1793	dna ligase
KFK26_13655	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KFK26_13665	COG1793	dna ligase
KFK26_13670	COG1201	RNA secondary structure unwinding
KFK26_13690	COG1278	Cold shock
KFK26_13695	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KFK26_13700	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KFK26_13710	COG3046	protein related to deoxyribodipyrimidine photolyase
KFK26_13715	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
KFK26_13735	COG2954	triphosphatase activity
KFK26_13750	COG1381	Involved in DNA repair and RecF pathway recombination
KFK26_13775	COG0481	GTPase activity
KFK26_13780	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KFK26_13795	COG1024	Enoyl-CoA hydratase
KFK26_13795	COG1250	3-hydroxyacyl-CoA dehydrogenase
KFK26_13815	COG1024	Enoyl-CoA hydratase
KFK26_13820	COG1960	acyl-CoA dehydrogenase activity
KFK26_13890	COG2353	YceI-like domain
KFK26_13900	COG2353	YceI-like domain
KFK26_13915	COG1760	l-serine dehydratase
KFK26_13925	COG0626	cystathionine gamma-synthase activity
KFK26_13930	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KFK26_13935	COG0739	heme binding
KFK26_13940	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KFK26_13945	COG1272	protein, Hemolysin III
KFK26_13975	COG0463	Glycosyl transferase, family 2
KFK26_13985	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KFK26_13995	COG4771	TonB-dependent receptor
KFK26_14000	COG1309	transcriptional regulator
KFK26_14010	COG1960	acyl-CoA dehydrogenase activity
KFK26_14040	COG0509	glycine decarboxylation via glycine cleavage system
KFK26_14045	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KFK26_14055	COG0330	HflC and HflK could
KFK26_14070	COG3956	TIGRFAM MazG family protein
KFK26_14080	COG0494	nUDIX hydrolase
KFK26_14090	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KFK26_14095	COG0837	glucose binding
KFK26_14110	COG1388	LysM domain
KFK26_14110	COG3858	chitin binding
KFK26_14120	COG3525	Glycosyl hydrolase, family 20, catalytic domain
KFK26_14130	COG1472	Belongs to the glycosyl hydrolase 3 family
KFK26_14200	COG3537	Alpha-1,2-mannosidase
KFK26_14245	COG1446	asparaginase
KFK26_14285	COG0643	Histidine kinase
KFK26_14285	COG0784	Response regulator, receiver
KFK26_14285	COG2198	Histidine kinase
KFK26_14290	COG0840	transmembrane signaling receptor activity
KFK26_14295	COG0835	chemotaxis
KFK26_14310	COG0189	ligase activity
KFK26_14320	COG1397	ADP-ribosylglycohydrolase
KFK26_14330	COG1199	ATP-dependent helicase activity
KFK26_14340	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KFK26_14345	COG1215	transferase activity, transferring glycosyl groups
KFK26_14355	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KFK26_14370	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
KFK26_14375	COG0535	radical SAM domain protein
KFK26_14380	COG0535	radical SAM domain protein
KFK26_14405	COG1643	Atp-dependent helicase
KFK26_14410	COG0783	Belongs to the Dps family
KFK26_14415	COG0514	ATP-dependent DNA helicase (RecQ)
KFK26_14435	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KFK26_14460	COG0602	queuosine metabolic process
KFK26_14470	COG2885	chlorophyll binding
KFK26_14475	COG0823	Involved in the tonB-independent uptake of proteins
KFK26_14485	COG0848	biopolymer transport protein
KFK26_14495	COG0824	Thioesterase
KFK26_14500	COG2255	four-way junction helicase activity
KFK26_14510	COG0632	four-way junction helicase activity
KFK26_14515	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KFK26_14520	COG0217	transcriptional regulatory protein
KFK26_14535	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KFK26_14550	COG0477	Major facilitator Superfamily
KFK26_14650	COG0316	Belongs to the HesB IscA family
KFK26_14650	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KFK26_14655	COG2154	pterin-4-alpha-carbinolamine dehydratase
KFK26_14665	COG0428	transporter
KFK26_14670	COG0428	transporter
KFK26_14675	COG3064	Membrane
KFK26_14685	COG1530	ribonuclease E activity
KFK26_14700	COG1054	Belongs to the UPF0176 family
KFK26_14720	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KFK26_14765	COG3039	Transposase
KFK26_14770	COG3039	Transposase
KFK26_14825	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KFK26_14825	COG1648	precorrin-2 dehydrogenase activity
KFK26_14850	COG0746	molybdenum cofactor guanylyltransferase activity
KFK26_14925	COG4206	TonB-dependent receptor
KFK26_14975	COG0531	amino acid
KFK26_14990	COG0006	proline dipeptidase activity
KFK26_15000	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KFK26_15015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KFK26_15020	COG3938	Belongs to the proline racemase family
KFK26_15030	COG0552	protein localization to endoplasmic reticulum
KFK26_15050	COG0784	Response regulator, receiver
KFK26_15050	COG4191	Histidine kinase
KFK26_15140	COG3040	lipid binding
KFK26_15180	COG0438	transferase activity, transferring glycosyl groups
KFK26_15190	COG0438	transferase activity, transferring glycosyl groups
KFK26_15195	COG0438	transferase activity, transferring glycosyl groups
KFK26_15250	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KFK26_15255	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KFK26_15265	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KFK26_15305	COG0556	nucleotide-excision repair
KFK26_15310	COG4969	Belongs to the N-Me-Phe pilin family
KFK26_15325	COG3039	Transposase
KFK26_15375	COG4695	Portal protein
KFK26_15420	COG3179	chitinase
KFK26_15615	COG1611	Belongs to the LOG family
KFK26_15630	COG2095	MarC family integral membrane protein
KFK26_15640	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KFK26_15675	COG1185	polyribonucleotide nucleotidyltransferase activity
KFK26_15680	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KFK26_15695	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KFK26_15700	COG0195	Participates in both transcription termination and antitermination
KFK26_15705	COG0779	Required for maturation of 30S ribosomal subunits
KFK26_15715	COG1007	ATP synthesis coupled electron transport
KFK26_15745	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
KFK26_15750	COG1034	ATP synthesis coupled electron transport
KFK26_15755	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KFK26_15760	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
KFK26_15765	COG0649	NAD binding
KFK26_15770	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KFK26_15780	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KFK26_15795	COG0149	triose-phosphate isomerase activity
KFK26_15845	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KFK26_15850	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KFK26_15855	COG0159	tryptophan synthase activity
KFK26_15865	COG0133	tryptophan synthase activity
KFK26_15875	COG0135	phosphoribosylanthranilate isomerase activity
KFK26_15880	COG0101	tRNA pseudouridine synthase activity
KFK26_15900	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KFK26_15905	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KFK26_15910	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KFK26_15915	COG2890	protein-(glutamine-N5) methyltransferase activity
KFK26_15965	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KFK26_15975	COG0412	Dienelactone hydrolase
KFK26_15995	COG0717	Belongs to the dCTP deaminase family
KFK26_16000	COG0489	protein tyrosine kinase activity
KFK26_16040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KFK26_16045	COG2311	Membrane
KFK26_16050	COG1047	Peptidyl-prolyl cis-trans
KFK26_16055	COG0791	NLP P60 protein
KFK26_16060	COG0791	NLP P60 protein
KFK26_16080	COG1301	dicarboxylic acid transport
KFK26_16085	COG1785	Belongs to the alkaline phosphatase family
KFK26_16090	COG0037	tRNA processing
KFK26_16095	COG1722	exodeoxyribonuclease VII activity
KFK26_16100	COG0142	geranyltranstransferase activity
KFK26_16125	COG0312	modulator of DNA gyrase
KFK26_16130	COG3028	Belongs to the UPF0307 family
KFK26_16135	COG0312	modulator of DNA gyrase
KFK26_16145	COG3164	Protein of unknown function
KFK26_16160	COG2968	Membrane
KFK26_16190	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KFK26_16215	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KFK26_16230	COG0495	leucyl-tRNA aminoacylation
KFK26_16240	COG3118	belongs to the thioredoxin family
KFK26_16290	COG3039	Transposase
KFK26_16310	COG3039	Transposase
KFK26_16390	COG2022	thiamine diphosphate biosynthetic process
KFK26_16400	COG0471	metal ion transport
KFK26_16400	COG3273	potassium ion transport
KFK26_16430	COG1970	mechanosensitive ion channel activity
KFK26_16460	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KFK26_16485	COG0308	aminopeptidase N
KFK26_16490	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KFK26_16500	COG3039	Transposase
KFK26_16510	COG2895	sulfate adenylyltransferase (ATP) activity
KFK26_16510	COG0529	Catalyzes the synthesis of activated sulfate
KFK26_16515	COG0175	sulfate reduction
KFK26_16520	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KFK26_16525	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KFK26_16530	COG0175	sulfate reduction
KFK26_16550	COG0784	Response regulator, receiver
KFK26_16550	COG2198	Histidine kinase
KFK26_16550	COG2205	protein histidine kinase activity
KFK26_16595	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
KFK26_16600	COG3588	fructose-bisphosphate aldolase
KFK26_16605	COG0469	pyruvate kinase activity
KFK26_16615	COG0126	phosphoglycerate kinase activity
KFK26_16645	COG0753	catalase activity
KFK26_16665	COG2207	Transcriptional regulator
KFK26_16665	COG1917	Cupin 2, conserved barrel domain protein
KFK26_16685	COG0823	Involved in the tonB-independent uptake of proteins
KFK26_16685	COG1506	peptidase
KFK26_16705	COG1297	OPT oligopeptide transporter protein
KFK26_16720	COG0587	DNA-directed DNA polymerase activity
KFK26_16835	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
KFK26_16975	COG3179	chitinase
KFK26_17045	COG1741	Belongs to the pirin family
KFK26_17050	COG1966	Carbon starvation protein
KFK26_17055	COG2879	small protein
KFK26_17090	COG3706	GGDEF domain
KFK26_17090	COG4251	negative regulation of phosphorylation
KFK26_17090	COG5001	Diguanylate cyclase
KFK26_17090	COG2203	Gaf domain
KFK26_17095	COG0629	single-stranded DNA binding
KFK26_17100	COG0142	geranyltranstransferase activity
KFK26_17125	COG0527	aspartate kinase activity
KFK26_17135	COG0384	phenazine biosynthesis protein PhzF
KFK26_17145	COG1764	response to oxidative stress
KFK26_17160	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KFK26_17165	COG1678	Uncharacterized ACR, COG1678
KFK26_17175	COG0519	Catalyzes the synthesis of GMP from XMP
KFK26_17205	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KFK26_17245	COG0693	protein deglycase activity
KFK26_17265	COG1959	2 iron, 2 sulfur cluster binding
KFK26_17270	COG0719	Fe-S assembly protein
KFK26_17275	COG0396	ATPase activity
KFK26_17280	COG0719	Fe-S assembly protein
KFK26_17285	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KFK26_17295	COG2146	nitrite reductase [NAD(P)H] activity
KFK26_17330	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KFK26_17345	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KFK26_17355	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
KFK26_17360	COG0174	glutamine synthetase
KFK26_17390	COG0326	Molecular chaperone. Has ATPase activity
KFK26_17395	COG2207	Transcriptional regulator
KFK26_17420	COG0657	acetylesterase activity
KFK26_17420	COG2755	lipolytic protein G-D-S-L family
KFK26_17445	COG0488	(ABC) transporter
KFK26_17480	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KFK26_17480	COG4651	solute:proton antiporter activity
KFK26_17495	COG4772	TonB-dependent receptor
KFK26_17505	COG4264	IucA IucC family
KFK26_17510	COG2814	Major facilitator Superfamily
KFK26_17520	COG0019	diaminopimelate decarboxylase activity
KFK26_17540	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
KFK26_17580	COG4206	TonB-dependent receptor
KFK26_17615	COG0542	response to heat
KFK26_17650	COG0534	Mate efflux family protein
KFK26_17665	COG0336	Belongs to the RNA methyltransferase TrmD family
KFK26_17670	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KFK26_17675	COG0228	four-way junction DNA binding
KFK26_17695	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KFK26_17705	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KFK26_17750	COG1555	photosystem II stabilization
KFK26_17755	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KFK26_17770	COG3178	'Phosphotransferase
KFK26_17775	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KFK26_17785	COG0628	permease
KFK26_17795	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KFK26_17810	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KFK26_17830	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KFK26_17835	COG0271	Belongs to the BolA IbaG family
KFK26_17845	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KFK26_17855	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
KFK26_17860	COG1137	ATPase activity
KFK26_17875	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KFK26_17880	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KFK26_17885	COG1660	Displays ATPase and GTPase activities
KFK26_17895	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KFK26_17900	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KFK26_17905	COG2239	Acts as a magnesium transporter
KFK26_17915	COG1294	oxidase, subunit
KFK26_17920	COG1271	oxidase subunit
KFK26_17935	COG1113	amino acid transport
KFK26_17950	COG2197	response regulator
KFK26_17955	COG0531	amino acid
KFK26_18010	COG0754	glutathionylspermidine amidase activity
KFK26_18035	COG1842	Phage shock protein A
KFK26_18050	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KFK26_18055	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KFK26_18065	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KFK26_18100	COG2201	protein-glutamate methylesterase activity
KFK26_18145	COG2201	protein-glutamate methylesterase activity
KFK26_18170	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KFK26_18220	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KFK26_18225	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KFK26_18250	COG3039	Transposase
KFK26_18265	COG0745	RESPONSE REGULATOR receiver
KFK26_18270	COG3039	Transposase
KFK26_18275	COG2205	protein histidine kinase activity
KFK26_18295	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KFK26_18335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KFK26_18335	COG3453	Protein conserved in bacteria
KFK26_18340	COG0725	ABC transporter, periplasmic molybdate-binding protein
KFK26_18345	COG4149	molybdate abc transporter
KFK26_18350	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KFK26_18370	COG0642	Histidine kinase
KFK26_18385	COG1028	Short-chain dehydrogenase reductase Sdr
KFK26_18395	COG1022	Amp-dependent synthetase and ligase
KFK26_18420	COG1376	ErfK ybiS ycfS ynhG family protein
KFK26_18425	COG0739	heme binding
KFK26_18435	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KFK26_18440	COG1301	dicarboxylic acid transport
KFK26_18460	COG2304	oxidoreductase activity
KFK26_18480	COG0714	Associated with various cellular activities
KFK26_18520	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KFK26_18545	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KFK26_18555	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KFK26_18580	COG1561	YicC-like family, N-terminal region
KFK26_18585	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KFK26_18600	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KFK26_18635	COG0006	proline dipeptidase activity
KFK26_18660	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KFK26_18670	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KFK26_18680	COG2912	Transglutaminase-like superfamily
KFK26_18685	COG1773	rubredoxin
KFK26_18690	COG0352	thiamine-phosphate diphosphorylase activity
KFK26_18715	COG0280	phosphate acetyltransferase
KFK26_18715	COG0281	malic enzyme
KFK26_18735	COG4191	Histidine kinase
KFK26_18750	COG0583	DNA-binding transcription factor activity
KFK26_18765	COG2197	response regulator
KFK26_18775	COG0642	Histidine kinase
KFK26_18790	COG2851	Citrate transporter
KFK26_18795	COG1028	Short-chain dehydrogenase reductase Sdr
KFK26_18800	COG1609	Transcriptional regulator
KFK26_18810	COG2211	Major facilitator Superfamily
KFK26_18835	COG1162	GTPase activity
KFK26_18860	COG0726	polysaccharide deacetylase
KFK26_18865	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KFK26_18910	COG0242	peptide deformylase activity
KFK26_18930	COG0714	Associated with various cellular activities
KFK26_18950	COG0537	adenosine 5'-monophosphoramidase activity
KFK26_18980	COG0314	molybdopterin synthase activity
KFK26_18985	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KFK26_18990	COG0315	cyclic pyranopterin monophosphate synthase activity
KFK26_19000	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KFK26_19005	COG1234	tRNA 3'-trailer cleavage
KFK26_19010	COG3642	lipopolysaccharide core region biosynthetic process
KFK26_19015	COG0859	PFAM glycosyl transferase family 9
KFK26_19025	COG0582	viral genome integration into host DNA
KFK26_19095	COG0631	protein serine/threonine phosphatase activity
KFK26_19130	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KFK26_19160	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KFK26_19170	COG0544	peptidyl-prolyl cis-trans isomerase activity
KFK26_19220	COG0473	3-isopropylmalate dehydrogenase activity
KFK26_19245	COG4783	chaperone-mediated protein folding
KFK26_19260	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KFK26_19270	COG0438	transferase activity, transferring glycosyl groups
KFK26_19275	COG0671	phosphoesterase, PA-phosphatase related
KFK26_19280	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KFK26_19300	COG2833	Protein of unknown function (DUF455)
KFK26_19320	COG0285	dihydrofolate synthase activity
KFK26_19330	COG0406	alpha-ribazole phosphatase activity
KFK26_19360	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KFK26_19365	COG4208	sulfate ABC transporter
KFK26_19370	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KFK26_19375	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KFK26_19380	COG0156	8-amino-7-oxononanoate synthase activity
KFK26_19405	COG0604	alcohol dehydrogenase
KFK26_19410	COG1902	pentaerythritol trinitrate reductase activity
KFK26_19410	COG0446	pyridine nucleotide-disulphide oxidoreductase
KFK26_19440	COG0584	glycerophosphoryl diester phosphodiesterase
KFK26_19480	COG0625	glutathione transferase activity
KFK26_19485	COG0039	L-malate dehydrogenase activity
KFK26_19490	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KFK26_19495	COG1217	gtp-binding protein TYPA
KFK26_19515	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
KFK26_19660	COG3781	membrane
KFK26_19670	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KFK26_19700	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
KFK26_19720	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KFK26_19745	COG3710	Transcriptional regulator
KFK26_19750	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KFK26_19760	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KFK26_19790	COG2226	methyltransferase
KFK26_19795	COG0066	3-isopropylmalate dehydratase activity
KFK26_19800	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KFK26_19830	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KFK26_19835	COG1538	Outer membrane efflux protein
KFK26_19840	COG1519	Transferase
KFK26_19845	COG1560	Kdo2-lipid A biosynthetic process
KFK26_19895	COG0308	aminopeptidase N
KFK26_19900	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KFK26_19910	COG0330	HflC and HflK could
KFK26_19915	COG0330	HflC and HflK could
KFK26_19935	COG0678	peroxiredoxin activity
KFK26_19945	COG2826	transposase and inactivated derivatives, IS30 family
KFK26_20045	COG3829	transcription factor binding
KFK26_20080	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KFK26_20085	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KFK26_20095	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KFK26_20100	COG1028	Short-chain dehydrogenase reductase Sdr
KFK26_20125	COG1399	metal-binding, possibly nucleic acid-binding protein
KFK26_20165	COG1518	maintenance of DNA repeat elements
KFK26_20170	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KFK26_20220	COG2188	Transcriptional regulator
KFK26_20235	COG1450	Type ii and iii secretion system protein
KFK26_20250	COG3166	PFAM Fimbrial assembly family protein
KFK26_20255	COG3156	type II secretion system protein K
KFK26_20260	COG4795	General secretion pathway protein
KFK26_20265	COG2165	general secretion pathway protein
KFK26_20270	COG4970	Tfp pilus assembly protein FimT
KFK26_20275	COG2165	general secretion pathway protein
KFK26_20280	COG1459	type II secretion system
KFK26_20290	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KFK26_20300	COG1404	Belongs to the peptidase S8 family
KFK26_20310	COG5295	Hep Hag repeat protein
KFK26_20315	COG0047	phosphoribosylformylglycinamidine synthase activity
KFK26_20315	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KFK26_20320	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KFK26_20325	COG4974	Belongs to the 'phage' integrase family
KFK26_20340	COG0795	lipopolysaccharide-transporting ATPase activity
KFK26_20350	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KFK26_20365	COG0525	valine-tRNA ligase activity
KFK26_20395	COG3039	Transposase
KFK26_20420	COG3039	Transposase
KFK26_20450	COG1183	phosphatidylcholine synthase activity
KFK26_20460	COG0442	prolyl-tRNA aminoacylation
KFK26_20475	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KFK26_20480	COG1127	ABC transporter
KFK26_20485	COG3218	ABC-type transport auxiliary lipoprotein component
KFK26_20485	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KFK26_20520	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KFK26_20525	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
KFK26_20525	COG0662	Cupin 2, conserved barrel domain protein
KFK26_20550	COG2086	electron transfer activity
KFK26_20575	COG3328	transposase activity
KFK26_20615	COG0626	cystathionine gamma-synthase activity
KFK26_20645	COG0625	glutathione transferase activity
KFK26_20655	COG0513	Belongs to the DEAD box helicase family
KFK26_20660	COG0720	synthase
KFK26_20670	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KFK26_20675	COG1956	GAF domain-containing protein
KFK26_20710	COG0339	signal peptide processing
KFK26_20760	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KFK26_20765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFK26_20815	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KFK26_20820	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KFK26_20825	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KFK26_20830	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KFK26_20835	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KFK26_20840	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KFK26_20850	COG0356	it plays a direct role in the translocation of protons across the membrane
KFK26_20870	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KFK26_20880	COG0508	dehydrogenase complex catalyzes the overall conversion of
KFK26_20910	COG2011	ABC-type metal ion transport system permease component
KFK26_20920	COG0697	spore germination
KFK26_20960	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KFK26_20965	COG1187	pseudouridine synthase activity
KFK26_20970	COG2813	Specifically methylates the guanine in position
KFK26_21000	COG2205	protein histidine kinase activity
KFK26_21000	COG2202	Pas domain
KFK26_21025	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KFK26_21075	COG0745	RESPONSE REGULATOR receiver
KFK26_21090	COG1404	Belongs to the peptidase S8 family
KFK26_21105	COG0842	Transport permease protein
KFK26_21110	COG1131	(ABC) transporter
KFK26_21115	COG0025	NhaP-type Na H and K H
KFK26_21125	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
KFK26_21135	COG1573	uracil-dna glycosylase
KFK26_21145	COG3384	dioxygenase
KFK26_21160	COG0667	Aldo Keto reductase
KFK26_21170	COG3590	peptidase
KFK26_21190	COG0531	amino acid
KFK26_21205	COG2972	Histidine kinase
KFK26_21260	COG1271	oxidase subunit
KFK26_21295	COG1324	tolerance protein
KFK26_21305	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KFK26_21310	COG0511	ligase activity, forming carbon-carbon bonds
KFK26_21320	COG0439	Biotin carboxylase
KFK26_21365	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KFK26_21500	COG2831	hemolysin activation secretion protein
KFK26_21535	COG2267	carboxylic ester hydrolase activity
KFK26_21540	COG2267	carboxylic ester hydrolase activity
KFK26_21550	COG0138	bifunctional purine biosynthesis protein purh
KFK26_21560	COG0151	Belongs to the GarS family
KFK26_21565	COG1136	(ABC) transporter
KFK26_21565	COG0577	efflux transmembrane transporter activity
KFK26_21575	COG1289	transmembrane transporter activity
KFK26_21590	COG2814	Major facilitator Superfamily
KFK26_21605	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
KFK26_21640	COG0745	RESPONSE REGULATOR receiver
KFK26_21685	COG0739	heme binding
KFK26_21700	COG2211	Major facilitator Superfamily
KFK26_21705	COG0708	Exodeoxyribonuclease III
KFK26_21720	COG1192	Involved in chromosome partitioning
KFK26_21725	COG1475	DNA binding
KFK26_21740	COG0463	Glycosyl transferase, family 2
KFK26_21760	COG0756	dUTP diphosphatase activity
KFK26_21765	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KFK26_21770	COG2003	Belongs to the UPF0758 family
KFK26_21775	COG0018	arginyl-trna synthetase
KFK26_21790	COG4221	oxidoreductase activity
KFK26_21815	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KFK26_21820	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KFK26_21835	COG3485	protocatechuate 3,4-dioxygenase
KFK26_21840	COG3485	protocatechuate 3,4-dioxygenase
KFK26_21880	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KFK26_21885	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KFK26_21895	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KFK26_21895	COG1042	CoA-binding domain protein
KFK26_21895	COG0045	succinate-CoA ligase (ADP-forming) activity
KFK26_21905	COG2239	Acts as a magnesium transporter
KFK26_21920	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KFK26_21925	COG3387	PFAM Glycoside hydrolase 15-related
KFK26_21940	COG3100	YcgL domain-containing protein
KFK26_21945	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KFK26_21955	COG0463	Glycosyl transferase, family 2
KFK26_21970	COG1028	Short-chain dehydrogenase reductase Sdr
KFK26_21980	COG0156	8-amino-7-oxononanoate synthase activity
KFK26_21985	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KFK26_21990	COG1040	competence protein
KFK26_21995	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KFK26_22005	COG0628	permease
KFK26_22015	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KFK26_22025	COG1595	DNA-templated transcription, initiation
KFK26_22030	COG0753	catalase activity
KFK26_22075	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KFK26_22080	COG0180	Tryptophanyl-tRNA synthetase
KFK26_22085	COG3237	CsbD-like
KFK26_22120	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KFK26_22135	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KFK26_22140	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
KFK26_22140	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
KFK26_22180	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KFK26_22200	COG1566	PFAM secretion protein HlyD family protein
KFK26_22220	COG1199	ATP-dependent helicase activity
KFK26_22260	COG0583	DNA-binding transcription factor activity
KFK26_22305	COG0625	glutathione transferase activity
KFK26_22340	COG4555	ABC transporter
KFK26_22350	COG1476	TRANSCRIPTIONal
KFK26_22375	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KFK26_22380	COG1131	(ABC) transporter
KFK26_22385	COG0842	Transport permease protein
KFK26_22395	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KFK26_22460	COG1181	Belongs to the D-alanine--D-alanine ligase family
KFK26_22470	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KFK26_22480	COG0564	pseudouridine synthase activity
KFK26_22510	COG0339	signal peptide processing
KFK26_22540	COG3254	rhamnose metabolic process
KFK26_22545	COG0738	Major facilitator superfamily
KFK26_22550	COG1414	Transcriptional regulator
KFK26_22565	COG2205	protein histidine kinase activity
KFK26_22575	COG3459	Glycosyltransferase 36 associated
KFK26_22580	COG2211	Major facilitator Superfamily
KFK26_22585	COG3265	gluconokinase activity
KFK26_22590	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KFK26_22660	COG1127	ABC transporter
KFK26_22665	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KFK26_22670	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KFK26_22685	COG2853	Lipoprotein
KFK26_22710	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KFK26_22775	COG0676	glucose-6-phosphate 1-epimerase activity
KFK26_22800	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KFK26_22810	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KFK26_22820	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KFK26_22825	COG1064	alcohol dehydrogenase
KFK26_22865	COG1522	sequence-specific DNA binding
KFK26_22870	COG3186	Phenylalanine-4-hydroxylase
KFK26_22905	COG0656	L-ascorbic acid biosynthetic process
KFK26_22910	COG2130	NADP-dependent
KFK26_22915	COG0667	Aldo Keto reductase
KFK26_22925	COG1187	pseudouridine synthase activity
KFK26_22940	COG1643	Atp-dependent helicase
KFK26_22945	COG4807	Protein conserved in bacteria
KFK26_22950	COG4948	Mandelate Racemase Muconate Lactonizing
KFK26_22955	COG0179	Fumarylacetoacetate (FAA) hydrolase
KFK26_22960	COG1028	Short-chain dehydrogenase reductase Sdr
KFK26_22980	COG3507	Belongs to the glycosyl hydrolase 43 family
KFK26_23020	COG3162	membrane
KFK26_23025	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KFK26_23040	COG0708	Exodeoxyribonuclease III
KFK26_23055	COG2091	lysine biosynthetic process via aminoadipic acid
KFK26_23065	COG3540	Alkaline phosphatase
KFK26_23070	COG0357	Ribosomal RNA small subunit methyltransferase G
KFK26_23090	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KFK26_23095	COG2159	amidohydrolase
KFK26_23105	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KFK26_23110	COG0583	DNA-binding transcription factor activity
KFK26_23115	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KFK26_23130	COG0210	DNA helicase
KFK26_23150	COG0531	amino acid
KFK26_23160	COG1322	Protein conserved in bacteria
KFK26_23170	COG0386	Belongs to the glutathione peroxidase family
KFK26_23220	COG0793	Belongs to the peptidase S41A family
KFK26_23225	COG4942	peptidase
KFK26_23235	COG2234	aminopeptidase activity
KFK26_23280	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KFK26_23285	COG0302	gtp cyclohydrolase
KFK26_23305	COG0477	Major facilitator Superfamily
KFK26_23325	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KFK26_23425	COG1929	Belongs to the glycerate kinase type-1 family
KFK26_23430	COG2271	Major facilitator Superfamily
KFK26_23445	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KFK26_23450	COG0861	Integral membrane protein TerC family
KFK26_23460	COG0584	glycerophosphoryl diester phosphodiesterase
KFK26_23470	COG0671	phosphoesterase, PA-phosphatase related
KFK26_23475	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KFK26_23480	COG0726	polysaccharide deacetylase
KFK26_23485	COG0706	membrane insertase activity