locus-tag	class	description
C0L90_00025	COG0187	DNA topoisomerase II activity
C0L90_00035	COG0501	Belongs to the peptidase M48B family
C0L90_00065	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
C0L90_00095	COG3039	Transposase
C0L90_00145	COG0793	Belongs to the peptidase S41A family
C0L90_00150	COG4942	peptidase
C0L90_00160	COG2234	aminopeptidase activity
C0L90_00170	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
C0L90_00185	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
C0L90_00195	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
C0L90_00205	COG1064	alcohol dehydrogenase
C0L90_00230	COG0493	'glutamate synthase
C0L90_00235	COG0067	glutamate synthase
C0L90_00235	COG0069	glutamate synthase activity
C0L90_00235	COG0070	glutamate synthase
C0L90_00305	COG1205	dead DEAH box helicase
C0L90_00305	COG1111	helicase
C0L90_00310	COG1272	protein, Hemolysin III
C0L90_00340	COG2032	superoxide dismutase activity
C0L90_00345	COG2204	response regulator
C0L90_00350	COG3852	Histidine kinase
C0L90_00355	COG0004	ammonium transporteR
C0L90_00360	COG0347	Belongs to the P(II) protein family
C0L90_00365	COG0174	glutamine synthetase
C0L90_00420	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C0L90_00430	COG2062	phosphohistidine phosphatase, SixA
C0L90_00435	COG0489	protein tyrosine kinase activity
C0L90_00455	COG1396	sequence-specific DNA binding
C0L90_00460	COG3550	peptidyl-serine autophosphorylation
C0L90_00465	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
C0L90_00470	COG1262	PFAM Formylglycine-generating sulfatase enzyme
C0L90_00485	COG1125	glycine betaine transport
C0L90_00485	COG0517	IMP dehydrogenase activity
C0L90_00500	COG1119	ATPase activity
C0L90_00515	COG1752	Esterase of the alpha-beta hydrolase superfamily
C0L90_00525	COG1522	sequence-specific DNA binding
C0L90_00530	COG3186	Phenylalanine-4-hydroxylase
C0L90_00560	COG1609	Transcriptional regulator
C0L90_00600	COG0366	Alpha amylase catalytic
C0L90_00605	COG0366	Alpha amylase catalytic
C0L90_00615	COG3039	Transposase
C0L90_00625	COG0183	Belongs to the thiolase family
C0L90_00665	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C0L90_00670	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
C0L90_00685	COG0028	Belongs to the TPP enzyme family
C0L90_00690	COG4191	Histidine kinase
C0L90_00715	COG3039	Transposase
C0L90_00725	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C0L90_00740	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C0L90_00745	COG3177	Filamentation induced by cAMP protein fic
C0L90_00750	COG0596	Alpha beta hydrolase
C0L90_00765	COG0318	PFAM AMP-dependent synthetase and ligase
C0L90_00770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C0L90_00785	COG1181	Belongs to the D-alanine--D-alanine ligase family
C0L90_00815	COG0564	pseudouridine synthase activity
C0L90_00845	COG0339	signal peptide processing
C0L90_00900	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C0L90_00905	COG1960	acyl-CoA dehydrogenase activity
C0L90_00960	COG0697	spore germination
C0L90_00970	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
C0L90_00975	COG1846	Transcriptional regulator
C0L90_00980	COG1764	response to oxidative stress
C0L90_01005	COG3501	Rhs element vgr protein
C0L90_01030	COG0656	L-ascorbic acid biosynthetic process
C0L90_01045	COG2130	NADP-dependent
C0L90_01060	COG1187	pseudouridine synthase activity
C0L90_01075	COG1643	Atp-dependent helicase
C0L90_01085	COG4807	Protein conserved in bacteria
C0L90_01090	COG2072	flavoprotein involved in K transport
C0L90_01110	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C0L90_01115	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C0L90_01155	COG3039	Transposase
C0L90_01200	COG0084	hydrolase, TatD family'
C0L90_01220	COG0583	DNA-binding transcription factor activity
C0L90_01225	COG2814	Major facilitator Superfamily
C0L90_01235	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C0L90_01240	COG1902	pentaerythritol trinitrate reductase activity
C0L90_01270	COG0745	RESPONSE REGULATOR receiver
C0L90_01290	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C0L90_01295	COG0583	DNA-binding transcription factor activity
C0L90_01325	COG0702	epimerase
C0L90_01330	COG1733	regulation of RNA biosynthetic process
C0L90_01365	COG3039	Transposase
C0L90_01385	COG3501	Rhs element vgr protein
C0L90_01410	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C0L90_01480	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C0L90_01485	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C0L90_01495	COG3485	protocatechuate 3,4-dioxygenase
C0L90_01500	COG3485	protocatechuate 3,4-dioxygenase
C0L90_01515	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C0L90_01520	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C0L90_01535	COG1414	Transcriptional regulator
C0L90_01625	COG1040	competence protein
C0L90_01630	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
C0L90_01730	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C0L90_01805	COG3264	Mechanosensitive ion channel
C0L90_01805	COG1511	domain protein
C0L90_01815	COG3039	Transposase
C0L90_01820	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C0L90_01830	COG2354	Protein conserved in bacteria
C0L90_01840	COG3706	GGDEF domain
C0L90_01840	COG0745	RESPONSE REGULATOR receiver
C0L90_01855	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
C0L90_01880	COG0702	epimerase
C0L90_01890	COG1028	Short-chain dehydrogenase reductase Sdr
C0L90_01935	COG0513	Belongs to the DEAD box helicase family
C0L90_01945	COG3039	Transposase
C0L90_01975	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C0L90_01990	COG3104	oligopeptide transport
C0L90_02020	COG1320	monovalent cation:proton antiporter activity
C0L90_02025	COG2212	antiporter activity
C0L90_02035	COG0651	ATP synthesis coupled electron transport
C0L90_02040	COG1006	Multisubunit Na H antiporter MnhC subunit
C0L90_02045	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C0L90_02045	COG2111	Na H antiporter
C0L90_02080	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
C0L90_02090	COG0456	acetyltransferase
C0L90_02135	COG0134	indole-3-glycerol-phosphate synthase activity
C0L90_02145	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C0L90_02190	COG2906	2 iron, 2 sulfur cluster binding
C0L90_02240	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
C0L90_02260	COG2814	Major facilitator Superfamily
C0L90_02270	COG2814	Major facilitator Superfamily
C0L90_02275	COG1289	transmembrane transporter activity
C0L90_02285	COG0151	Belongs to the GarS family
C0L90_02290	COG0138	bifunctional purine biosynthesis protein purh
C0L90_02295	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C0L90_02305	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
C0L90_02360	COG0439	Biotin carboxylase
C0L90_02370	COG0511	ligase activity, forming carbon-carbon bonds
C0L90_02390	COG1324	tolerance protein
C0L90_02410	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C0L90_02430	COG0534	Mate efflux family protein
C0L90_02435	COG0616	signal peptide processing
C0L90_02445	COG1028	Short-chain dehydrogenase reductase Sdr
C0L90_02465	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C0L90_02465	COG1754	DNA topoisomerase type I activity
C0L90_02485	COG0758	DNA mediated transformation
C0L90_02490	COG1652	LysM domain
C0L90_02495	COG0242	peptide deformylase activity
C0L90_02505	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C0L90_02505	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C0L90_02555	COG1560	Kdo2-lipid A biosynthetic process
C0L90_02565	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C0L90_02595	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C0L90_02600	COG3118	belongs to the thioredoxin family
C0L90_02610	COG2884	Cell division ATP-binding protein ftsE
C0L90_02615	COG2177	Part of the ABC transporter FtsEX involved in
C0L90_02620	COG3437	response regulator, receiver
C0L90_02630	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C0L90_02635	COG2860	membrane
C0L90_02640	COG1252	NADH dehydrogenase
C0L90_02660	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
C0L90_02680	COG3039	Transposase
C0L90_02695	COG3039	Transposase
C0L90_02705	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C0L90_02720	COG3386	PFAM SMP-30 Gluconolaconase
C0L90_02735	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C0L90_02780	COG2353	YceI-like domain
C0L90_02830	COG3501	Rhs element vgr protein
C0L90_02890	COG4221	oxidoreductase activity
C0L90_02945	COG0697	spore germination
C0L90_02950	COG4305	rare lipoprotein A
C0L90_02955	COG5297	Belongs to the glycosyl hydrolase family 6
C0L90_02965	COG1113	amino acid transport
C0L90_02975	COG0598	Magnesium transport protein CorA
C0L90_03055	COG5001	Diguanylate cyclase
C0L90_03055	COG3300	MHYT domain
C0L90_03080	COG5297	Belongs to the glycosyl hydrolase family 6
C0L90_03080	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
C0L90_03085	COG0659	secondary active sulfate transmembrane transporter activity
C0L90_03090	COG3706	GGDEF domain
C0L90_03120	COG3275	phosphorelay sensor kinase activity
C0L90_03155	COG1505	serine-type exopeptidase activity
C0L90_03175	COG2832	Protein of unknown function (DUF454)
C0L90_03195	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
C0L90_03205	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
C0L90_03240	COG3300	MHYT domain
C0L90_03240	COG5001	Diguanylate cyclase
C0L90_03245	COG0308	aminopeptidase N
C0L90_03265	COG1077	Cell shape determining protein MreB Mrl
C0L90_03270	COG1792	Involved in formation and maintenance of cell shape
C0L90_03285	COG0772	Belongs to the SEDS family
C0L90_03310	COG2951	lytic endotransglycosylase activity
C0L90_03315	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C0L90_03320	COG1686	Belongs to the peptidase S11 family
C0L90_03360	COG1051	belongs to the nudix hydrolase family
C0L90_03360	COG1056	cytidyltransferase-related domain
C0L90_03395	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
C0L90_03400	COG0673	inositol 2-dehydrogenase activity
C0L90_03405	COG2823	Periplasmic or secreted lipoprotein
C0L90_03410	COG4251	negative regulation of phosphorylation
C0L90_03415	COG0784	Response regulator, receiver
C0L90_03420	COG4191	Histidine kinase
C0L90_03425	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C0L90_03450	COG3039	Transposase
C0L90_03465	COG3250	beta-galactosidase activity
C0L90_03490	COG1609	Transcriptional regulator
C0L90_03495	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C0L90_03500	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C0L90_03515	COG1215	transferase activity, transferring glycosyl groups
C0L90_03520	COG1649	PFAM Uncharacterised BCR, COG1649
C0L90_03520	COG0726	polysaccharide deacetylase
C0L90_03540	COG3039	Transposase
C0L90_03625	COG2205	protein histidine kinase activity
C0L90_03630	COG0745	RESPONSE REGULATOR receiver
C0L90_03655	COG3791	Glutathione-dependent formaldehyde-activating
C0L90_03670	COG3039	Transposase
C0L90_03685	COG0488	(ABC) transporter
C0L90_03715	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C0L90_03725	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C0L90_03725	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C0L90_03755	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C0L90_03780	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
C0L90_03785	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
C0L90_03795	COG2205	protein histidine kinase activity
C0L90_03800	COG0745	RESPONSE REGULATOR receiver
C0L90_03830	COG0277	FAD linked oxidase domain protein
C0L90_03885	COG3116	cell division
C0L90_03900	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C0L90_03905	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C0L90_03925	COG1181	Belongs to the D-alanine--D-alanine ligase family
C0L90_03930	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C0L90_03955	COG0741	lytic transglycosylase activity
C0L90_03955	COG1196	nuclear chromosome segregation
C0L90_03955	COG0739	heme binding
C0L90_03970	COG0494	nUDIX hydrolase
C0L90_03985	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C0L90_04000	COG0604	alcohol dehydrogenase
C0L90_04000	COG1028	Short-chain dehydrogenase reductase Sdr
C0L90_04000	COG3321	synthase
C0L90_04060	COG2226	methyltransferase
C0L90_04090	COG2826	transposase and inactivated derivatives, IS30 family
C0L90_04115	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
C0L90_04130	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C0L90_04140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C0L90_04145	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C0L90_04155	COG0667	Aldo Keto reductase
C0L90_04185	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
C0L90_04195	COG2175	clavaminate synthase activity
C0L90_04205	COG4181	ATPase activity
C0L90_04220	COG0642	Histidine kinase
C0L90_04235	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C0L90_04275	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C0L90_04300	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
C0L90_04315	COG0123	including yeast histone deacetylase and acetoin utilization protein
C0L90_04320	COG2096	Adenosyltransferase
C0L90_04335	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C0L90_04340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C0L90_04360	COG1802	Transcriptional regulator
C0L90_04370	COG3384	dioxygenase
C0L90_04375	COG0583	DNA-binding transcription factor activity
C0L90_04380	COG0318	PFAM AMP-dependent synthetase and ligase
C0L90_04390	COG1024	Enoyl-CoA hydratase
C0L90_04410	COG3386	PFAM SMP-30 Gluconolaconase
C0L90_04460	COG2197	response regulator
C0L90_04470	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C0L90_04475	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C0L90_04480	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C0L90_04490	COG0583	DNA-binding transcription factor activity
C0L90_04495	COG3634	alkyl hydroperoxide reductase activity
C0L90_04505	COG2890	protein-(glutamine-N5) methyltransferase activity
C0L90_04545	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C0L90_04545	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C0L90_04560	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
C0L90_04585	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
C0L90_04590	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
C0L90_04615	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C0L90_04625	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C0L90_04655	COG1295	ribonuclease BN
C0L90_04660	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C0L90_04665	COG1254	Belongs to the acylphosphatase family
C0L90_04680	COG0521	Mo-molybdopterin cofactor biosynthetic process
C0L90_04695	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
C0L90_04720	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C0L90_04735	COG0012	GTP binding
C0L90_04765	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C0L90_04770	COG0250	Participates in transcription elongation, termination and antitermination
C0L90_04785	COG0081	regulation of translation
C0L90_04790	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C0L90_04810	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
C0L90_04835	COG0051	transcription antitermination factor activity, RNA binding
C0L90_04850	COG0089	rRNA binding
C0L90_04855	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C0L90_04875	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
C0L90_04880	COG0255	Belongs to the universal ribosomal protein uL29 family
C0L90_04885	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
C0L90_04895	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
C0L90_04905	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C0L90_04925	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
C0L90_04930	COG1841	ribosomal large subunit assembly
C0L90_04935	COG0200	Binds to the 23S rRNA
C0L90_04940	COG0201	protein transport
C0L90_04945	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C0L90_04960	COG0202	RNA polymerase activity
C0L90_04965	COG0203	ribosomal protein L17
C0L90_04980	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
C0L90_05005	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C0L90_05015	COG0625	glutathione transferase activity
C0L90_05045	COG3039	Transposase
C0L90_05065	COG0446	pyridine nucleotide-disulphide oxidoreductase
C0L90_05065	COG1902	pentaerythritol trinitrate reductase activity
C0L90_05070	COG0604	alcohol dehydrogenase
C0L90_05100	COG0156	8-amino-7-oxononanoate synthase activity
C0L90_05105	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C0L90_05110	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
C0L90_05115	COG4208	sulfate ABC transporter
C0L90_05120	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
C0L90_05130	COG1063	alcohol dehydrogenase
C0L90_05155	COG0406	alpha-ribazole phosphatase activity
C0L90_05165	COG0285	dihydrofolate synthase activity
C0L90_05185	COG2833	Protein of unknown function (DUF455)
C0L90_05215	COG0671	phosphoesterase, PA-phosphatase related
C0L90_05220	COG0438	transferase activity, transferring glycosyl groups
C0L90_05230	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
C0L90_05235	COG5002	protein histidine kinase activity
C0L90_05245	COG4783	chaperone-mediated protein folding
C0L90_05260	COG0473	3-isopropylmalate dehydrogenase activity
C0L90_05300	COG3039	Transposase
C0L90_05325	COG0544	peptidyl-prolyl cis-trans isomerase activity
C0L90_05330	COG0740	serine-type endopeptidase activity
C0L90_05365	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C0L90_05390	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C0L90_05405	COG0631	protein serine/threonine phosphatase activity
C0L90_05425	COG3039	Transposase
C0L90_05435	COG0859	PFAM glycosyl transferase family 9
C0L90_05445	COG1234	tRNA 3'-trailer cleavage
C0L90_05450	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C0L90_05465	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C0L90_05470	COG0314	molybdopterin synthase activity
C0L90_05505	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
C0L90_05515	COG0537	adenosine 5'-monophosphoramidase activity
C0L90_05535	COG0714	Associated with various cellular activities
C0L90_05555	COG1399	metal-binding, possibly nucleic acid-binding protein
C0L90_05580	COG1028	Short-chain dehydrogenase reductase Sdr
C0L90_05595	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C0L90_05600	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C0L90_05635	COG3829	transcription factor binding
C0L90_05670	COG3039	Transposase
C0L90_05745	COG0330	HflC and HflK could
C0L90_05750	COG0330	HflC and HflK could
C0L90_05760	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C0L90_05765	COG0308	aminopeptidase N
C0L90_05800	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
C0L90_05840	COG0328	RNA-DNA hybrid ribonuclease activity
C0L90_05840	COG0406	alpha-ribazole phosphatase activity
C0L90_05885	COG0587	DNA-directed DNA polymerase activity
C0L90_05905	COG1297	OPT oligopeptide transporter protein
C0L90_05920	COG0823	Involved in the tonB-independent uptake of proteins
C0L90_05920	COG1506	peptidase
C0L90_05930	COG1917	Cupin 2, conserved barrel domain protein
C0L90_05930	COG2207	Transcriptional regulator
C0L90_05975	COG0753	catalase activity
C0L90_06015	COG3551	Protein conserved in bacteria
C0L90_06045	COG2194	sulfuric ester hydrolase activity
C0L90_06055	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C0L90_06060	COG0745	RESPONSE REGULATOR receiver
C0L90_06065	COG0642	Histidine kinase
C0L90_06075	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
C0L90_06080	COG2894	cell division
C0L90_06095	COG4585	Histidine kinase
C0L90_06100	COG2197	response regulator
C0L90_06115	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C0L90_06140	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
C0L90_06205	COG3501	Rhs element vgr protein
C0L90_06215	COG2826	transposase and inactivated derivatives, IS30 family
C0L90_06240	COG3039	Transposase
C0L90_06355	COG3501	Rhs element vgr protein
C0L90_06420	COG1842	Phage shock protein A
C0L90_06445	COG0754	glutathionylspermidine amidase activity
C0L90_06525	COG0531	amino acid
C0L90_06530	COG2197	response regulator
C0L90_06545	COG1113	amino acid transport
C0L90_06575	COG3039	Transposase
C0L90_06585	COG1294	oxidase, subunit
C0L90_06595	COG2239	Acts as a magnesium transporter
C0L90_06605	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C0L90_06610	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C0L90_06625	COG3039	Transposase
C0L90_06650	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C0L90_06665	COG1137	ATPase activity
C0L90_06670	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
C0L90_06680	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
C0L90_06690	COG0271	Belongs to the BolA IbaG family
C0L90_06695	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C0L90_06720	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C0L90_06745	COG0628	permease
C0L90_06755	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C0L90_06760	COG3178	'Phosphotransferase
C0L90_06770	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C0L90_06775	COG1555	photosystem II stabilization
C0L90_06795	COG3039	Transposase
C0L90_06815	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C0L90_06820	COG0719	Fe-S assembly protein
C0L90_06825	COG0396	ATPase activity
C0L90_06830	COG0719	Fe-S assembly protein
C0L90_06835	COG1959	2 iron, 2 sulfur cluster binding
C0L90_06890	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C0L90_06925	COG0519	Catalyzes the synthesis of GMP from XMP
C0L90_06940	COG1678	Uncharacterized ACR, COG1678
C0L90_06950	COG0540	Belongs to the ATCase OTCase family
C0L90_06960	COG1764	response to oxidative stress
C0L90_06970	COG0384	phenazine biosynthesis protein PhzF
C0L90_06980	COG0527	aspartate kinase activity
C0L90_07010	COG3039	Transposase
C0L90_07020	COG0142	geranyltranstransferase activity
C0L90_07025	COG0629	single-stranded DNA binding
C0L90_07030	COG2203	Gaf domain
C0L90_07030	COG4251	negative regulation of phosphorylation
C0L90_07030	COG5001	Diguanylate cyclase
C0L90_07030	COG3706	GGDEF domain
C0L90_07075	COG2879	small protein
C0L90_07080	COG1966	Carbon starvation protein
C0L90_07085	COG1741	Belongs to the pirin family
C0L90_07095	COG3501	Rhs element vgr protein
C0L90_07180	COG1515	deoxyribonuclease V activity
C0L90_07200	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C0L90_07205	COG2202	Pas domain
C0L90_07205	COG2200	EAL domain
C0L90_07205	COG2199	diguanylate cyclase activity
C0L90_07210	COG0835	chemotaxis
C0L90_07215	COG0840	transmembrane signaling receptor activity
C0L90_07245	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
C0L90_07285	COG0735	belongs to the Fur family
C0L90_07315	COG2826	transposase and inactivated derivatives, IS30 family
C0L90_07405	COG3039	Transposase
C0L90_07465	COG5002	protein histidine kinase activity
C0L90_07465	COG5001	Diguanylate cyclase
C0L90_07470	COG1187	pseudouridine synthase activity
C0L90_07495	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C0L90_07500	COG0475	glutathione-regulated potassium exporter activity
C0L90_07505	COG5000	phosphorelay sensor kinase activity
C0L90_07505	COG5002	protein histidine kinase activity
C0L90_07510	COG0745	RESPONSE REGULATOR receiver
C0L90_07515	COG1538	Outer membrane efflux protein
C0L90_07540	COG1132	(ABC) transporter
C0L90_07565	COG3039	Transposase
C0L90_07610	COG3118	belongs to the thioredoxin family
C0L90_07640	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C0L90_07660	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
C0L90_07685	COG2968	Membrane
C0L90_07695	COG1530	ribonuclease E activity
C0L90_07700	COG3164	Protein of unknown function
C0L90_07710	COG0312	modulator of DNA gyrase
C0L90_07715	COG3028	Belongs to the UPF0307 family
C0L90_07720	COG0312	modulator of DNA gyrase
C0L90_07735	COG4104	PAAR repeat-containing protein
C0L90_07745	COG0142	geranyltranstransferase activity
C0L90_07750	COG1722	exodeoxyribonuclease VII activity
C0L90_07755	COG0037	tRNA processing
C0L90_07760	COG1785	Belongs to the alkaline phosphatase family
C0L90_07765	COG1301	dicarboxylic acid transport
C0L90_07770	COG4106	trans-aconitate 2-methyltransferase activity
C0L90_07780	COG0791	NLP P60 protein
C0L90_07785	COG0791	NLP P60 protein
C0L90_07790	COG1047	Peptidyl-prolyl cis-trans
C0L90_07795	COG2311	Membrane
C0L90_07800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C0L90_07830	COG3039	Transposase
C0L90_07840	COG2826	transposase and inactivated derivatives, IS30 family
C0L90_07870	COG2826	transposase and inactivated derivatives, IS30 family
C0L90_07875	COG3039	Transposase
C0L90_07890	COG0489	protein tyrosine kinase activity
C0L90_07900	COG0717	Belongs to the dCTP deaminase family
C0L90_07915	COG3039	Transposase
C0L90_07935	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C0L90_07945	COG3039	Transposase
C0L90_07955	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C0L90_07970	COG2826	transposase and inactivated derivatives, IS30 family
C0L90_07980	COG0433	COG0433 Predicted ATPase
C0L90_08010	COG2890	protein-(glutamine-N5) methyltransferase activity
C0L90_08020	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C0L90_08025	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C0L90_08060	COG0133	tryptophan synthase activity
C0L90_08130	COG1028	Short-chain dehydrogenase reductase Sdr
C0L90_08150	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C0L90_08170	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
C0L90_08175	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
C0L90_08180	COG1034	ATP synthesis coupled electron transport
C0L90_08185	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
C0L90_08190	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C0L90_08200	COG0713	ATP synthesis coupled electron transport
C0L90_08215	COG1007	ATP synthesis coupled electron transport
C0L90_08230	COG0195	Participates in both transcription termination and antitermination
C0L90_08235	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
C0L90_08250	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
C0L90_08285	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C0L90_08290	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C0L90_08300	COG2095	MarC family integral membrane protein
C0L90_08315	COG3039	Transposase
C0L90_08320	COG1611	Belongs to the LOG family
C0L90_08365	COG4969	Belongs to the N-Me-Phe pilin family
C0L90_08370	COG0556	nucleotide-excision repair
C0L90_08400	COG3723	Recombinational DNA repair protein, rece pathway
C0L90_08485	COG0270	DNA (cytosine-5-)-methyltransferase activity
C0L90_08690	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
C0L90_08700	COG2986	histidine ammonia-lyase
C0L90_08750	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C0L90_08755	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
C0L90_08760	COG0077	Prephenate dehydratase
C0L90_08760	COG1605	Chorismate mutase
C0L90_08790	COG3039	Transposase
C0L90_08800	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
C0L90_08815	COG0583	DNA-binding transcription factor activity
C0L90_08830	COG2336	PFAM SpoVT AbrB
C0L90_08865	COG0840	transmembrane signaling receptor activity
C0L90_08890	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
C0L90_08895	COG4191	Histidine kinase
C0L90_08895	COG0784	Response regulator, receiver
C0L90_08910	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C0L90_08930	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C0L90_08945	COG1595	DNA-templated transcription, initiation
C0L90_08995	COG2244	polysaccharide biosynthetic process
C0L90_09025	COG2264	protein methyltransferase activity
C0L90_09035	COG0438	transferase activity, transferring glycosyl groups
C0L90_09050	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
C0L90_09055	COG1132	(ABC) transporter
C0L90_09065	COG0477	Major facilitator Superfamily
C0L90_09085	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C0L90_09100	COG1253	flavin adenine dinucleotide binding
C0L90_09115	COG0306	phosphate transporter
C0L90_09155	COG0148	phosphopyruvate hydratase activity
C0L90_09160	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
C0L90_09185	COG2840	Smr protein MutS2
C0L90_09200	COG1238	metal cluster binding
C0L90_09215	COG1534	Rna-binding protein
C0L90_09225	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C0L90_09230	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C0L90_09240	COG1923	regulation of RNA biosynthetic process
C0L90_09245	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C0L90_09250	COG1546	Belongs to the CinA family
C0L90_09275	COG2137	regulation of response to DNA damage stimulus
C0L90_09285	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
C0L90_09340	COG1741	Belongs to the pirin family
C0L90_09345	COG0583	DNA-binding transcription factor activity
C0L90_09370	COG0352	thiamine-phosphate diphosphorylase activity
C0L90_09370	COG0351	phosphomethylpyrimidine kinase
C0L90_09380	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
C0L90_09385	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C0L90_09400	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C0L90_09410	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
C0L90_09415	COG3734	2-keto-3-deoxy-galactonokinase
C0L90_09430	COG0800	Aldolase
C0L90_09455	COG1070	Carbohydrate kinase
C0L90_09465	COG0477	Major facilitator Superfamily
C0L90_09485	COG0860	N-Acetylmuramoyl-L-alanine amidase
C0L90_09500	COG0617	tRNA 3'-terminal CCA addition
C0L90_09520	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
C0L90_09550	COG1472	Belongs to the glycosyl hydrolase 3 family
C0L90_09570	COG2203	Gaf domain
C0L90_09570	COG4251	negative regulation of phosphorylation
C0L90_09570	COG3706	GGDEF domain
C0L90_09570	COG5001	Diguanylate cyclase
C0L90_09580	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
C0L90_09590	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
C0L90_09605	COG0671	phosphoesterase, PA-phosphatase related
C0L90_09625	COG1794	racemase activity, acting on amino acids and derivatives
C0L90_09635	COG0697	spore germination
C0L90_09640	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C0L90_09665	COG1012	belongs to the aldehyde dehydrogenase family
C0L90_09725	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C0L90_09740	COG0124	histidyl-tRNA synthetase
C0L90_09795	COG0140	phosphoribosyl-ATP diphosphatase activity
C0L90_09795	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C0L90_09825	COG0235	Class ii aldolase
C0L90_09830	COG0531	amino acid
C0L90_09835	COG0531	amino acid
C0L90_09845	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C0L90_09850	COG0277	FAD linked oxidase domain protein
C0L90_09930	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C0L90_09935	COG2258	MOSC domain
C0L90_09940	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
C0L90_09945	COG0505	Belongs to the CarA family
C0L90_09955	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C0L90_09960	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C0L90_09970	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C0L90_09985	COG3279	Response regulator of the LytR AlgR family
C0L90_10010	COG2205	protein histidine kinase activity
C0L90_10010	COG0784	Response regulator, receiver
C0L90_10010	COG2198	Histidine kinase
C0L90_10015	COG1024	Enoyl-CoA hydratase
C0L90_10020	COG0318	PFAM AMP-dependent synthetase and ligase
C0L90_10050	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C0L90_10080	COG0840	transmembrane signaling receptor activity
C0L90_10090	COG0835	chemotaxis
C0L90_10105	COG0840	transmembrane signaling receptor activity
C0L90_10110	COG0840	transmembrane signaling receptor activity
C0L90_10115	COG0840	transmembrane signaling receptor activity
C0L90_10130	COG0840	transmembrane signaling receptor activity
C0L90_10140	COG0840	transmembrane signaling receptor activity
C0L90_10145	COG0840	transmembrane signaling receptor activity
C0L90_10175	COG0840	transmembrane signaling receptor activity
C0L90_10180	COG2826	transposase and inactivated derivatives, IS30 family
C0L90_10200	COG0745	RESPONSE REGULATOR receiver
C0L90_10210	COG0835	chemotaxis
C0L90_10215	COG1192	Involved in chromosome partitioning
C0L90_10220	COG1360	Flagellar Motor Protein
C0L90_10225	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C0L90_10245	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C0L90_10285	COG3039	Transposase
C0L90_10350	COG0643	Histidine kinase
C0L90_10350	COG2198	Histidine kinase
C0L90_10370	COG0455	bacterial-type flagellum organization
C0L90_10395	COG5001	Diguanylate cyclase
C0L90_10395	COG3300	MHYT domain
C0L90_10400	COG3300	MHYT domain
C0L90_10400	COG5001	Diguanylate cyclase
C0L90_10405	COG1684	flagellar biosynthetic protein fliR
C0L90_10410	COG1987	bacterial-type flagellum assembly
C0L90_10420	COG3190	flagellar
C0L90_10470	COG1677	Flagellar hook-basal body complex protein FliE
C0L90_10505	COG1028	Short-chain dehydrogenase reductase Sdr
C0L90_10515	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C0L90_10530	COG2204	response regulator
C0L90_10535	COG2201	protein-glutamate methylesterase activity
C0L90_10565	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C0L90_10570	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C0L90_10585	COG3951	Flagellar rod assembly protein muramidase FlgJ
C0L90_10585	COG1705	Flagellar rod assembly protein muramidase FlgJ
C0L90_10590	COG1706	bacterial-type flagellum-dependent cell motility
C0L90_10595	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
C0L90_10600	COG4786	Flagellar basal body rod
C0L90_10610	COG4787	bacterial-type flagellum-dependent cell motility
C0L90_10615	COG1749	Flagellar hook protein flgE
C0L90_10620	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
C0L90_10625	COG1558	bacterial-type flagellum-dependent cell motility
C0L90_10635	COG0835	chemotaxis
C0L90_10635	COG0784	Response regulator, receiver
C0L90_10655	COG5002	protein histidine kinase activity
C0L90_10665	COG4585	Histidine kinase
C0L90_10700	COG0482	sulfurtransferase activity
C0L90_10710	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
C0L90_10715	COG0542	response to heat
C0L90_10720	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C0L90_10740	COG0492	ferredoxin-NADP+ reductase activity
C0L90_10745	COG1674	ftsk spoiiie
C0L90_10770	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C0L90_10790	COG0038	chloride channel
C0L90_10795	COG0183	Belongs to the thiolase family
C0L90_10800	COG1250	3-hydroxyacyl-CoA dehydrogenase
C0L90_10800	COG1024	Enoyl-CoA hydratase
C0L90_10810	COG0105	UTP biosynthetic process
C0L90_10835	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C0L90_10840	COG1160	GTP binding
C0L90_10845	COG0303	'Molybdopterin
C0L90_10855	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C0L90_10865	COG2826	transposase and inactivated derivatives, IS30 family
C0L90_10890	COG0746	molybdenum cofactor guanylyltransferase activity
C0L90_10915	COG1648	precorrin-2 dehydrogenase activity
C0L90_10915	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C0L90_10955	COG3039	Transposase
C0L90_10980	COG5001	Diguanylate cyclase
C0L90_11000	COG4566	intracellular signal transduction
C0L90_11040	COG3501	Rhs element vgr protein
C0L90_11130	COG1024	Enoyl-CoA hydratase
C0L90_11135	COG1024	Enoyl-CoA hydratase
C0L90_11145	COG1024	Enoyl-CoA hydratase
C0L90_11160	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
C0L90_11270	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C0L90_11275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C0L90_11330	COG1858	cytochrome C peroxidase
C0L90_11360	COG0515	serine threonine protein kinase
C0L90_11365	COG0631	protein serine/threonine phosphatase activity
C0L90_11400	COG3501	Rhs element vgr protein
C0L90_11425	COG2826	transposase and inactivated derivatives, IS30 family
C0L90_11440	COG3039	Transposase
C0L90_11525	COG3039	Transposase
C0L90_11540	COG2154	pterin-4-alpha-carbinolamine dehydratase
C0L90_11555	COG3064	Membrane
C0L90_11565	COG1530	ribonuclease E activity
C0L90_11600	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
C0L90_11650	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C0L90_11675	COG0811	peptide transport
C0L90_11700	COG4591	ABC-type transport system involved in lipoprotein release permease component
C0L90_11715	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C0L90_11730	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
C0L90_11745	COG0354	folic acid binding
C0L90_11760	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C0L90_11770	COG0363	glucosamine-6-phosphate deaminase activity
C0L90_11775	COG0129	dihydroxy-acid dehydratase activity
C0L90_11780	COG0800	Aldolase
C0L90_11860	COG0784	Response regulator, receiver
C0L90_11860	COG2205	protein histidine kinase activity
C0L90_11875	COG2183	response to ionizing radiation
C0L90_11885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C0L90_11885	COG0723	plastoquinol--plastocyanin reductase activity
C0L90_11900	COG3243	poly(R)-hydroxyalkanoic acid synthase
C0L90_11910	COG1183	phosphatidylcholine synthase activity
C0L90_11915	COG1028	Short-chain dehydrogenase reductase Sdr
C0L90_11930	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
C0L90_11940	COG0668	transmembrane transport
C0L90_11950	COG0590	tRNA wobble adenosine to inosine editing
C0L90_11955	COG1321	iron dependent repressor
C0L90_11960	COG1914	H( )-stimulated, divalent metal cation uptake system
C0L90_11990	COG0583	DNA-binding transcription factor activity
C0L90_12015	COG0583	DNA-binding transcription factor activity
C0L90_12020	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C0L90_12030	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C0L90_12030	COG0519	Catalyzes the synthesis of GMP from XMP
C0L90_12055	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C0L90_12065	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C0L90_12070	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
C0L90_12085	COG0539	negative regulation of cytoplasmic translation
C0L90_12090	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
C0L90_12095	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C0L90_12105	COG2957	Belongs to the agmatine deiminase family
C0L90_12115	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C0L90_12140	COG0395	ABC-type sugar transport system, permease component
C0L90_12145	COG1175	transmembrane transport
C0L90_12175	COG2350	Protein conserved in bacteria
C0L90_12180	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
C0L90_12185	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C0L90_12190	COG1187	pseudouridine synthase activity
C0L90_12210	COG0436	Aminotransferase
C0L90_12215	COG4133	protoheme IX ABC transporter activity
C0L90_12265	COG1278	Cold shock
C0L90_12275	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C0L90_12280	COG4988	ABC transporter
C0L90_12290	COG1271	oxidase subunit
C0L90_12360	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C0L90_12365	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C0L90_12370	COG0137	argininosuccinate synthase activity
C0L90_12375	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C0L90_12390	COG2166	iron-sulfur cluster assembly
C0L90_12405	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C0L90_12415	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C0L90_12430	COG4302	ethanolamine ammonia-lyase activity
C0L90_12445	COG4677	pectinesterase activity
C0L90_12480	COG0402	S-adenosylhomocysteine deaminase activity
C0L90_12500	COG1509	lysine 2,3-aminomutase activity
C0L90_12505	COG5001	Diguanylate cyclase
C0L90_12505	COG3300	MHYT domain
C0L90_12520	COG0483	inositol monophosphate 1-phosphatase activity
C0L90_12555	COG0513	Belongs to the DEAD box helicase family
C0L90_12565	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
C0L90_12575	COG0625	glutathione transferase activity
C0L90_12590	COG4681	YaeQ
C0L90_12595	COG2081	HI0933 family
C0L90_12600	COG1716	ATPase activity
C0L90_12600	COG5001	Diguanylate cyclase
C0L90_12605	COG0501	Belongs to the peptidase M48B family
C0L90_12615	COG1028	Short-chain dehydrogenase reductase Sdr
C0L90_12640	COG0860	N-Acetylmuramoyl-L-alanine amidase
C0L90_12645	COG0802	atpase or kinase
C0L90_12650	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C0L90_12650	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
C0L90_12655	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C0L90_12675	COG3039	Transposase
C0L90_12685	COG1262	PFAM Formylglycine-generating sulfatase enzyme
C0L90_12735	COG0835	chemotaxis
C0L90_12740	COG0840	transmembrane signaling receptor activity
C0L90_12770	COG2969	positive regulation of protein catabolic process
C0L90_12775	COG0625	glutathione transferase activity
C0L90_12780	COG2857	Cytochrome c1
C0L90_12785	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C0L90_12790	COG0723	plastoquinol--plastocyanin reductase activity
C0L90_12800	COG0741	lytic transglycosylase activity
C0L90_12830	COG1702	phosphate starvation-inducible protein PhoH
C0L90_12850	COG4535	Mg2 and Co2 transporter CorC
C0L90_12865	COG1012	belongs to the aldehyde dehydrogenase family
C0L90_12870	COG1177	transmembrane transport
C0L90_12875	COG1176	ABC-type spermidine putrescine transport system, permease component I
C0L90_12885	COG3842	ATPase activity
C0L90_12915	COG3039	Transposase
C0L90_12940	COG0174	glutamine synthetase
C0L90_12945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C0L90_12950	COG0745	RESPONSE REGULATOR receiver
C0L90_12950	COG3706	GGDEF domain
C0L90_12955	COG0477	Major facilitator Superfamily
C0L90_12965	COG0243	molybdopterin cofactor binding
C0L90_12990	COG1121	(ABC) transporter
C0L90_13000	COG2733	membrane
C0L90_13005	COG0784	Response regulator, receiver
C0L90_13005	COG2205	protein histidine kinase activity
C0L90_13005	COG5002	protein histidine kinase activity
C0L90_13015	COG3039	Transposase
C0L90_13025	COG0477	Major facilitator Superfamily
C0L90_13060	COG3039	Transposase
C0L90_13070	COG2902	Dehydrogenase
C0L90_13080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C0L90_13085	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C0L90_13100	COG1609	Transcriptional regulator
C0L90_13105	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C0L90_13105	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C0L90_13110	COG1105	Belongs to the carbohydrate kinase PfkB family
C0L90_13115	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C0L90_13115	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C0L90_13125	COG3501	Rhs element vgr protein
C0L90_13165	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C0L90_13175	COG1862	Preprotein translocase
C0L90_13245	COG0405	Gamma-glutamyltransferase
C0L90_13250	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C0L90_13270	COG0742	ribosomal rna small subunit methyltransferase
C0L90_13275	COG0326	Molecular chaperone. Has ATPase activity
C0L90_13320	COG4206	TonB-dependent receptor
C0L90_13375	COG3039	Transposase
C0L90_13380	COG3039	Transposase
C0L90_13390	COG0531	amino acid
C0L90_13405	COG0006	proline dipeptidase activity
C0L90_13415	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C0L90_13430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C0L90_13435	COG3938	Belongs to the proline racemase family
C0L90_13445	COG0552	protein localization to endoplasmic reticulum
C0L90_13460	COG1194	a g-specific adenine glycosylase
C0L90_13470	COG0784	Response regulator, receiver
C0L90_13470	COG4191	Histidine kinase
C0L90_13475	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C0L90_13500	COG3040	lipid binding
C0L90_13510	COG1960	acyl-CoA dehydrogenase activity
C0L90_13560	COG0438	transferase activity, transferring glycosyl groups
C0L90_13565	COG0438	transferase activity, transferring glycosyl groups
C0L90_13610	COG0776	regulation of translation
C0L90_13620	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C0L90_13625	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
C0L90_13630	COG0291	Belongs to the bacterial ribosomal protein bL35 family
C0L90_13635	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C0L90_13675	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
C0L90_13680	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C0L90_13685	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C0L90_13690	COG3115	cell septum assembly
C0L90_13715	COG0316	Belongs to the HesB IscA family
C0L90_13750	COG0288	reversible hydration of carbon dioxide
C0L90_13775	COG3844	kynureninase activity
C0L90_13785	COG2925	Exonuclease
C0L90_13795	COG0667	Aldo Keto reductase
C0L90_13810	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C0L90_13870	COG0494	nUDIX hydrolase
C0L90_13880	COG1024	Enoyl-CoA hydratase
C0L90_13890	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C0L90_13895	COG0659	secondary active sulfate transmembrane transporter activity
C0L90_13920	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C0L90_13925	COG0573	inorganic phosphate transmembrane transporter activity
C0L90_13930	COG0581	inorganic phosphate transmembrane transporter activity
C0L90_13940	COG0704	Plays a role in the regulation of phosphate uptake
C0L90_13950	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C0L90_13960	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C0L90_13975	COG0557	exoribonuclease II activity
C0L90_14005	COG1960	acyl-CoA dehydrogenase activity
C0L90_14015	COG1410	methionine synthase
C0L90_14015	COG0646	methionine synthase
C0L90_14020	COG0646	methionine synthase
C0L90_14020	COG1410	methionine synthase
C0L90_14030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C0L90_14070	COG0386	Belongs to the glutathione peroxidase family
C0L90_14080	COG1725	Transcriptional regulator
C0L90_14085	COG1131	(ABC) transporter
C0L90_14125	COG3039	Transposase
C0L90_14155	COG2850	peptidyl-arginine hydroxylation
C0L90_14190	COG1132	(ABC) transporter
C0L90_14220	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
C0L90_14235	COG0443	Heat shock 70 kDa protein
C0L90_14250	COG0497	DNA recombination
C0L90_14260	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C0L90_14270	COG2914	Belongs to the UPF0125 (RnfH) family
C0L90_14280	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
C0L90_14305	COG3039	Transposase
C0L90_14360	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C0L90_14370	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
C0L90_14375	COG0174	glutamine synthetase
C0L90_14405	COG3706	GGDEF domain
C0L90_14440	COG0415	Belongs to the DNA photolyase family
C0L90_14445	COG0305	Participates in initiation and elongation during chromosome replication
C0L90_14455	COG0367	asparagine synthase
C0L90_14485	COG0084	hydrolase, TatD family'
C0L90_14490	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C0L90_14530	COG0840	transmembrane signaling receptor activity
C0L90_14545	COG3039	Transposase
C0L90_14555	COG3039	Transposase
C0L90_14590	COG0386	Belongs to the glutathione peroxidase family
C0L90_14690	COG2814	Major facilitator Superfamily
C0L90_14695	COG1566	PFAM secretion protein HlyD family protein
C0L90_14710	COG2207	Transcriptional regulator
C0L90_14740	COG4774	siderophore transport
C0L90_14750	COG0367	asparagine synthase
C0L90_14755	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C0L90_14765	COG1393	Belongs to the ArsC family
C0L90_14785	COG0024	Methionine aminopeptidase
C0L90_14850	COG0575	Belongs to the CDS family
C0L90_14855	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
C0L90_14860	COG0750	zinc metalloprotease
C0L90_14875	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C0L90_14905	COG0825	malonyl-CoA metabolic process
C0L90_14980	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C0L90_14995	COG2040	homocysteine
C0L90_15000	COG0833	amino acid
C0L90_15005	COG0346	lactoylglutathione lyase activity
C0L90_15025	COG2878	Part of a membrane complex involved in electron transport
C0L90_15045	COG1595	DNA-templated transcription, initiation
C0L90_15070	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C0L90_15085	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C0L90_15090	COG0251	oxidation-reduction process
C0L90_15100	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
C0L90_15100	COG0392	lysyltransferase activity
C0L90_15140	COG2814	Major facilitator Superfamily
C0L90_15145	COG1902	pentaerythritol trinitrate reductase activity
C0L90_15160	COG2824	Alkylphosphonate utilization operon protein PhnA
C0L90_15170	COG1047	Peptidyl-prolyl cis-trans
C0L90_15210	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C0L90_15225	COG1451	nucleotide metabolic process
C0L90_15245	COG0183	Belongs to the thiolase family
C0L90_15260	COG0745	RESPONSE REGULATOR receiver
C0L90_15260	COG3706	GGDEF domain
C0L90_15275	COG1793	dna ligase
C0L90_15275	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
C0L90_15285	COG1793	dna ligase
C0L90_15290	COG1201	RNA secondary structure unwinding
C0L90_15310	COG1278	Cold shock
C0L90_15315	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
C0L90_15330	COG3046	protein related to deoxyribodipyrimidine photolyase
C0L90_15335	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
C0L90_15390	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C0L90_15405	COG1250	3-hydroxyacyl-CoA dehydrogenase
C0L90_15405	COG1024	Enoyl-CoA hydratase
C0L90_15425	COG1024	Enoyl-CoA hydratase
C0L90_15430	COG1960	acyl-CoA dehydrogenase activity
C0L90_15505	COG2353	YceI-like domain
C0L90_15530	COG1760	l-serine dehydratase
C0L90_15540	COG0626	cystathionine gamma-synthase activity
C0L90_15545	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C0L90_15550	COG0739	heme binding
C0L90_15560	COG1272	protein, Hemolysin III
C0L90_15580	COG0516	GMP reductase activity
C0L90_15580	COG0517	IMP dehydrogenase activity
C0L90_15585	COG0463	Glycosyl transferase, family 2
C0L90_15595	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
C0L90_15605	COG4771	TonB-dependent receptor
C0L90_15610	COG1309	transcriptional regulator
C0L90_15620	COG1960	acyl-CoA dehydrogenase activity
C0L90_15665	COG0330	HflC and HflK could
C0L90_15675	COG1742	UPF0060 membrane protein
C0L90_15680	COG3956	TIGRFAM MazG family protein
C0L90_15690	COG0494	nUDIX hydrolase
C0L90_15700	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C0L90_15705	COG0837	glucose binding
C0L90_15720	COG1388	LysM domain
C0L90_15720	COG3858	chitin binding
C0L90_15740	COG1472	Belongs to the glycosyl hydrolase 3 family
C0L90_15765	COG2801	Transposase and inactivated derivatives
C0L90_15775	COG2826	transposase and inactivated derivatives, IS30 family
C0L90_15790	COG3039	Transposase
C0L90_15845	COG3537	Alpha-1,2-mannosidase
C0L90_15890	COG3142	Participates in the control of copper homeostasis
C0L90_15895	COG1446	asparaginase
C0L90_15905	COG2304	oxidoreductase activity
C0L90_15935	COG0840	transmembrane signaling receptor activity
C0L90_15940	COG0835	chemotaxis
C0L90_15955	COG0189	ligase activity
C0L90_15965	COG1397	ADP-ribosylglycohydrolase
C0L90_15975	COG1199	ATP-dependent helicase activity
C0L90_15985	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C0L90_16000	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C0L90_16050	COG1643	Atp-dependent helicase
C0L90_16055	COG0783	Belongs to the Dps family
C0L90_16070	COG0514	ATP-dependent DNA helicase (RecQ)
C0L90_16085	COG3039	Transposase
C0L90_16100	COG1187	pseudouridine synthase activity
C0L90_16150	COG0602	queuosine metabolic process
C0L90_16160	COG2885	chlorophyll binding
C0L90_16165	COG0823	Involved in the tonB-independent uptake of proteins
C0L90_16175	COG0848	biopolymer transport protein
C0L90_16185	COG0824	Thioesterase
C0L90_16205	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
C0L90_16225	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
C0L90_16240	COG0477	Major facilitator Superfamily
C0L90_16275	COG0488	(ABC) transporter
C0L90_16305	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C0L90_16305	COG4651	solute:proton antiporter activity
C0L90_16335	COG0640	Transcriptional regulator
C0L90_16350	COG4772	TonB-dependent receptor
C0L90_16360	COG4264	IucA IucC family
C0L90_16365	COG2814	Major facilitator Superfamily
C0L90_16375	COG0019	diaminopimelate decarboxylase activity
C0L90_16430	COG4206	TonB-dependent receptor
C0L90_16465	COG0542	response to heat
C0L90_16490	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
C0L90_16500	COG0534	Mate efflux family protein
C0L90_16550	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C0L90_16560	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C0L90_16600	COG2172	sigma factor antagonist activity
C0L90_16605	COG1366	Belongs to the anti-sigma-factor antagonist family
C0L90_16610	COG1366	Belongs to the anti-sigma-factor antagonist family
C0L90_16620	COG0326	Molecular chaperone. Has ATPase activity
C0L90_16625	COG2207	Transcriptional regulator
C0L90_16680	COG3209	COG3209 Rhs family protein
C0L90_16690	COG3209	COG3209 Rhs family protein
C0L90_16700	COG3501	Rhs element vgr protein
C0L90_16710	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C0L90_16715	COG1845	cytochrome c oxidase, subunit III
C0L90_16720	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C0L90_16740	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
C0L90_16755	COG0728	peptidoglycan biosynthetic process
C0L90_16760	COG0268	Binds directly to 16S ribosomal RNA
C0L90_16780	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C0L90_16785	COG0824	Thioesterase
C0L90_16800	COG1946	Acyl-CoA thioesterase
C0L90_16810	COG1595	DNA-templated transcription, initiation
C0L90_16865	COG1877	trehalose-phosphatase activity
C0L90_16870	COG3387	PFAM Glycoside hydrolase 15-related
C0L90_16905	COG0564	pseudouridine synthase activity
C0L90_16910	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C0L90_16915	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C0L90_16915	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C0L90_16930	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C0L90_16975	COG2194	sulfuric ester hydrolase activity
C0L90_16980	COG4969	Belongs to the N-Me-Phe pilin family
C0L90_16990	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
C0L90_16995	COG0237	dephospho-CoA kinase activity
C0L90_17000	COG2205	protein histidine kinase activity
C0L90_17005	COG0745	RESPONSE REGULATOR receiver
C0L90_17025	COG3039	Transposase
C0L90_17040	COG3039	Transposase
C0L90_17055	COG2801	Transposase and inactivated derivatives
C0L90_17065	COG3039	Transposase
C0L90_17105	COG3273	potassium ion transport
C0L90_17105	COG0471	metal ion transport
C0L90_17135	COG1970	mechanosensitive ion channel activity
C0L90_17170	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C0L90_17180	COG0308	aminopeptidase N
C0L90_17185	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C0L90_17195	COG2895	sulfate adenylyltransferase (ATP) activity
C0L90_17195	COG0529	Catalyzes the synthesis of activated sulfate
C0L90_17205	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C0L90_17235	COG2205	protein histidine kinase activity
C0L90_17235	COG2198	Histidine kinase
C0L90_17235	COG0784	Response regulator, receiver
C0L90_17280	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C0L90_17285	COG3588	fructose-bisphosphate aldolase
C0L90_17295	COG0469	pyruvate kinase activity
C0L90_17325	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C0L90_17340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C0L90_17340	COG3453	Protein conserved in bacteria
C0L90_17345	COG0725	ABC transporter, periplasmic molybdate-binding protein
C0L90_17350	COG4149	molybdate abc transporter
C0L90_17355	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
C0L90_17375	COG0642	Histidine kinase
C0L90_17380	COG0745	RESPONSE REGULATOR receiver
C0L90_17390	COG1028	Short-chain dehydrogenase reductase Sdr
C0L90_17400	COG1022	Amp-dependent synthetase and ligase
C0L90_17425	COG1376	ErfK ybiS ycfS ynhG family protein
C0L90_17430	COG0739	heme binding
C0L90_17445	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C0L90_17450	COG1301	dicarboxylic acid transport
C0L90_17470	COG2304	oxidoreductase activity
C0L90_17490	COG0714	Associated with various cellular activities
C0L90_17525	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
C0L90_17550	COG0254	rRNA binding
C0L90_17560	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C0L90_17570	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C0L90_17575	COG1758	RNA polymerase activity
C0L90_17590	COG1561	YicC-like family, N-terminal region
C0L90_17610	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C0L90_17640	COG0006	proline dipeptidase activity
C0L90_17685	COG2912	Transglutaminase-like superfamily
C0L90_17690	COG1773	rubredoxin
C0L90_17695	COG0352	thiamine-phosphate diphosphorylase activity
C0L90_17720	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
C0L90_17760	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C0L90_17785	COG0671	phosphoesterase, PA-phosphatase related
C0L90_17800	COG3781	membrane
C0L90_17810	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C0L90_17825	COG3039	Transposase
C0L90_17840	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
C0L90_17850	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
C0L90_17875	COG3710	Transcriptional regulator
C0L90_17920	COG2226	methyltransferase
C0L90_17950	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
C0L90_17955	COG1538	Outer membrane efflux protein
C0L90_17960	COG1519	Transferase
C0L90_17965	COG1560	Kdo2-lipid A biosynthetic process
C0L90_17985	COG3039	Transposase
C0L90_17995	COG2826	transposase and inactivated derivatives, IS30 family
C0L90_18060	COG3039	Transposase
C0L90_18075	COG0280	phosphate acetyltransferase
C0L90_18075	COG0281	malic enzyme
C0L90_18095	COG4191	Histidine kinase
C0L90_18110	COG0583	DNA-binding transcription factor activity
C0L90_18130	COG2197	response regulator
C0L90_18140	COG0642	Histidine kinase
C0L90_18160	COG2851	Citrate transporter
C0L90_18165	COG1028	Short-chain dehydrogenase reductase Sdr
C0L90_18175	COG1609	Transcriptional regulator
C0L90_18185	COG2211	Major facilitator Superfamily
C0L90_18215	COG0436	Aminotransferase
C0L90_18235	COG0726	polysaccharide deacetylase
C0L90_18240	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C0L90_18260	COG0402	S-adenosylhomocysteine deaminase activity
C0L90_18310	COG0242	peptide deformylase activity
C0L90_18315	COG3039	Transposase
C0L90_18350	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C0L90_18410	COG2188	Transcriptional regulator
C0L90_18425	COG1450	Type ii and iii secretion system protein
C0L90_18440	COG3166	PFAM Fimbrial assembly family protein
C0L90_18445	COG3156	type II secretion system protein K
C0L90_18450	COG4795	General secretion pathway protein
C0L90_18455	COG2165	general secretion pathway protein
C0L90_18460	COG4970	Tfp pilus assembly protein FimT
C0L90_18465	COG2165	general secretion pathway protein
C0L90_18470	COG1459	type II secretion system
C0L90_18480	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C0L90_18485	COG1404	Belongs to the peptidase S8 family
C0L90_18490	COG5295	Hep Hag repeat protein
C0L90_18500	COG0047	phosphoribosylformylglycinamidine synthase activity
C0L90_18500	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C0L90_18510	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C0L90_18515	COG4974	Belongs to the 'phage' integrase family
C0L90_18530	COG0795	lipopolysaccharide-transporting ATPase activity
C0L90_18565	COG0525	valine-tRNA ligase activity
C0L90_18595	COG2826	transposase and inactivated derivatives, IS30 family
C0L90_18605	COG2826	transposase and inactivated derivatives, IS30 family
C0L90_18630	COG1183	phosphatidylcholine synthase activity
C0L90_18655	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C0L90_18660	COG1127	ABC transporter
C0L90_18665	COG3218	ABC-type transport auxiliary lipoprotein component
C0L90_18665	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C0L90_18710	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C0L90_18715	COG0662	Cupin 2, conserved barrel domain protein
C0L90_18715	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
C0L90_18745	COG2086	electron transfer activity
C0L90_18815	COG0626	cystathionine gamma-synthase activity
C0L90_18845	COG0625	glutathione transferase activity
C0L90_18860	COG0513	Belongs to the DEAD box helicase family
C0L90_18870	COG0720	synthase
C0L90_18885	COG1956	GAF domain-containing protein
C0L90_18895	COG0546	phosphoglycolate phosphatase activity
C0L90_18925	COG0339	signal peptide processing
C0L90_18975	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C0L90_19065	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
C0L90_19075	COG0356	it plays a direct role in the translocation of protons across the membrane
C0L90_19095	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C0L90_19105	COG0508	dehydrogenase complex catalyzes the overall conversion of
C0L90_19140	COG2011	ABC-type metal ion transport system permease component
C0L90_19150	COG0697	spore germination
C0L90_19190	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C0L90_19195	COG1187	pseudouridine synthase activity
C0L90_19200	COG2813	Specifically methylates the guanine in position
C0L90_19230	COG2202	Pas domain
C0L90_19230	COG2205	protein histidine kinase activity
C0L90_19255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C0L90_19260	COG1522	sequence-specific DNA binding
C0L90_19305	COG0745	RESPONSE REGULATOR receiver
C0L90_19320	COG1404	Belongs to the peptidase S8 family
C0L90_19335	COG0842	Transport permease protein
C0L90_19340	COG1131	(ABC) transporter
C0L90_19345	COG0025	NhaP-type Na H and K H
C0L90_19355	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
C0L90_19365	COG1573	uracil-dna glycosylase
C0L90_19375	COG3384	dioxygenase
C0L90_19405	COG3590	peptidase
C0L90_19425	COG0531	amino acid
C0L90_19450	COG3685	Protein conserved in bacteria
C0L90_19455	COG3546	catalase activity
C0L90_19480	COG3039	Transposase
C0L90_19510	COG1271	oxidase subunit
C0L90_19515	COG1294	oxidase, subunit
C0L90_19550	COG1063	alcohol dehydrogenase
C0L90_19655	COG1473	amidohydrolase
C0L90_19660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C0L90_19665	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C0L90_19690	COG5383	Protein conserved in bacteria
C0L90_19740	COG3023	N-Acetylmuramoyl-L-alanine amidase
C0L90_19750	COG4948	Mandelate Racemase Muconate Lactonizing
C0L90_19775	COG0531	amino acid
C0L90_19795	COG4682	membrane
C0L90_19800	COG2133	pyrroloquinoline quinone binding
C0L90_19820	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C0L90_19830	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C0L90_19835	COG1610	YqeY-like protein
C0L90_19855	COG1295	ribonuclease BN
C0L90_19860	COG0358	DNA primase activity
C0L90_19920	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
C0L90_19935	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C0L90_20000	COG0739	heme binding
C0L90_20015	COG2211	Major facilitator Superfamily
C0L90_20020	COG0708	Exodeoxyribonuclease III
C0L90_20035	COG1192	Involved in chromosome partitioning
C0L90_20040	COG1475	DNA binding
C0L90_20055	COG0463	Glycosyl transferase, family 2
C0L90_20080	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C0L90_20105	COG4221	oxidoreductase activity
C0L90_20145	COG1166	arginine decarboxylase activity
C0L90_20195	COG0606	chelatase, subunit chli
C0L90_20220	COG4943	cyclic-guanylate-specific phosphodiesterase activity
C0L90_20240	COG3039	Transposase
C0L90_20295	COG1090	epimerase
C0L90_20305	COG0642	Histidine kinase
C0L90_20320	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C0L90_20355	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C0L90_20365	COG1595	DNA-templated transcription, initiation
C0L90_20370	COG0753	catalase activity
C0L90_20395	COG0697	spore germination
C0L90_20420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C0L90_20425	COG0180	Tryptophanyl-tRNA synthetase
C0L90_20430	COG3237	CsbD-like
C0L90_20485	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
C0L90_20485	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
C0L90_20495	COG3228	Belongs to the MtfA family
C0L90_20510	COG2205	protein histidine kinase activity
C0L90_20515	COG0745	RESPONSE REGULATOR receiver
C0L90_20525	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C0L90_20580	COG3039	Transposase
C0L90_20585	COG1566	PFAM secretion protein HlyD family protein
C0L90_20600	COG1199	ATP-dependent helicase activity
C0L90_20645	COG0583	DNA-binding transcription factor activity
C0L90_20695	COG0625	glutathione transferase activity
C0L90_20705	COG2826	transposase and inactivated derivatives, IS30 family
C0L90_20730	COG4555	ABC transporter
C0L90_20740	COG1476	TRANSCRIPTIONal
C0L90_20760	COG1230	cation diffusion facilitator family transporter
C0L90_20765	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C0L90_20770	COG1131	(ABC) transporter
C0L90_20775	COG0842	Transport permease protein
C0L90_20785	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C0L90_20820	COG2951	lytic endotransglycosylase activity
C0L90_20835	COG1196	nuclear chromosome segregation
C0L90_20840	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C0L90_20850	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C0L90_20865	COG0045	succinate-CoA ligase (ADP-forming) activity
C0L90_20865	COG1042	CoA-binding domain protein
C0L90_20865	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C0L90_20875	COG2239	Acts as a magnesium transporter
C0L90_20900	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C0L90_20905	COG3387	PFAM Glycoside hydrolase 15-related
C0L90_20920	COG3100	YcgL domain-containing protein
C0L90_20925	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C0L90_20935	COG0463	Glycosyl transferase, family 2
C0L90_20950	COG1028	Short-chain dehydrogenase reductase Sdr
C0L90_20980	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C0L90_20995	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C0L90_21110	COG0210	DNA helicase
C0L90_21130	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C0L90_21145	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C0L90_21160	COG2159	amidohydrolase
C0L90_21165	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C0L90_21170	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C0L90_21190	COG0357	Ribosomal RNA small subunit methyltransferase G
C0L90_21195	COG3540	Alkaline phosphatase
C0L90_21205	COG2091	lysine biosynthetic process via aminoadipic acid
C0L90_21220	COG0708	Exodeoxyribonuclease III
C0L90_21235	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C0L90_21240	COG3162	membrane
C0L90_21295	COG1028	Short-chain dehydrogenase reductase Sdr
C0L90_21300	COG0179	Fumarylacetoacetate (FAA) hydrolase
C0L90_21310	COG4948	Mandelate Racemase Muconate Lactonizing
C0L90_21315	COG3254	rhamnose metabolic process
C0L90_21320	COG0738	Major facilitator superfamily
C0L90_21325	COG1414	Transcriptional regulator
C0L90_21335	COG2205	protein histidine kinase activity
C0L90_21345	COG3459	Glycosyltransferase 36 associated
C0L90_21350	COG2211	Major facilitator Superfamily
C0L90_21355	COG3265	gluconokinase activity
C0L90_21360	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C0L90_21395	COG3039	Transposase
C0L90_21405	COG3039	Transposase
C0L90_21410	COG2911	Protein conserved in bacteria
C0L90_21415	COG0729	surface antigen
C0L90_21420	COG4771	TonB-dependent receptor
C0L90_21425	COG0457	Tetratricopeptide repeat
C0L90_21435	COG0752	glycyl-tRNA synthetase alpha subunit
C0L90_21440	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C0L90_21450	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C0L90_21450	COG0519	Catalyzes the synthesis of GMP from XMP
C0L90_21460	COG0805	protein transport
C0L90_21465	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C0L90_21470	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C0L90_21480	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
C0L90_21510	COG2974	May be involved in recombination
C0L90_21515	COG0037	tRNA processing
C0L90_21540	COG3661	Belongs to the glycosyl hydrolase 67 family
C0L90_21550	COG4948	Mandelate Racemase Muconate Lactonizing
C0L90_21560	COG1472	Belongs to the glycosyl hydrolase 3 family
C0L90_21565	COG0246	Mannitol dehydrogenase
C0L90_21600	COG2826	transposase and inactivated derivatives, IS30 family
C0L90_21625	COG3693	PFAM glycoside hydrolase, family 10
C0L90_21650	COG2211	Major facilitator Superfamily
C0L90_21665	COG3039	Transposase
C0L90_21700	COG2937	Belongs to the GPAT DAPAT family
C0L90_21740	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
C0L90_21760	COG0210	DNA helicase
C0L90_21775	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
C0L90_21840	COG0676	glucose-6-phosphate 1-epimerase activity
C0L90_21855	COG0730	response to heat
C0L90_21890	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C0L90_21895	COG0302	gtp cyclohydrolase
C0L90_21925	COG2826	transposase and inactivated derivatives, IS30 family
C0L90_21935	COG0477	Major facilitator Superfamily
C0L90_21950	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C0L90_21995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C0L90_22045	COG3237	CsbD-like
C0L90_22070	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C0L90_22125	COG4772	TonB-dependent receptor
C0L90_22135	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
C0L90_22165	COG3039	Transposase
C0L90_22215	COG0564	pseudouridine synthase activity
C0L90_22230	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C0L90_22245	COG3039	Transposase
C0L90_22265	COG3039	Transposase
C0L90_22290	COG3039	Transposase
C0L90_22365	COG1074	ATP-dependent DNA helicase activity
C0L90_22370	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
C0L90_22385	COG3039	Transposase
C0L90_22390	COG3039	Transposase
C0L90_22400	COG1136	(ABC) transporter
C0L90_22420	COG1127	ABC transporter
C0L90_22425	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C0L90_22430	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C0L90_22445	COG2853	Lipoprotein
C0L90_22470	COG0386	Belongs to the glutathione peroxidase family
C0L90_22480	COG1322	Protein conserved in bacteria
C0L90_22485	COG3039	Transposase
C0L90_22510	COG1929	Belongs to the glycerate kinase type-1 family
C0L90_22515	COG2271	Major facilitator Superfamily
C0L90_22530	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C0L90_22540	COG0861	Integral membrane protein TerC family
C0L90_22555	COG0584	glycerophosphoryl diester phosphodiesterase
C0L90_22565	COG0671	phosphoesterase, PA-phosphatase related
C0L90_22570	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
C0L90_22575	COG0726	polysaccharide deacetylase
C0L90_22590	COG0230	Belongs to the bacterial ribosomal protein bL34 family