locus-tag	class	description
BXO512_000040	COG0583	DNA-binding transcription factor activity
BXO512_000050	COG3039	Transposase
BXO512_000150	COG3039	Transposase
BXO512_000160	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BXO512_000180	COG0557	exoribonuclease II activity
BXO512_000205	COG1960	acyl-CoA dehydrogenase activity
BXO512_000210	COG2226	methyltransferase
BXO512_000215	COG0646	methionine synthase
BXO512_000215	COG1410	methionine synthase
BXO512_000220	COG1410	methionine synthase
BXO512_000220	COG0646	methionine synthase
BXO512_000230	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BXO512_000240	COG1609	Transcriptional regulator
BXO512_000255	COG2900	Belongs to the SlyX family
BXO512_000270	COG0386	Belongs to the glutathione peroxidase family
BXO512_000280	COG1725	Transcriptional regulator
BXO512_000285	COG1131	(ABC) transporter
BXO512_000345	COG2850	peptidyl-arginine hydroxylation
BXO512_000380	COG1132	(ABC) transporter
BXO512_000395	COG0583	DNA-binding transcription factor activity
BXO512_000410	COG1605	Chorismate mutase
BXO512_000410	COG0287	Prephenate dehydrogenase
BXO512_000415	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BXO512_000420	COG0484	heat shock protein binding
BXO512_000425	COG0443	Heat shock 70 kDa protein
BXO512_000430	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BXO512_000440	COG0497	DNA recombination
BXO512_000450	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BXO512_000455	COG2914	Belongs to the UPF0125 (RnfH) family
BXO512_000465	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BXO512_000480	COG1960	acyl-CoA dehydrogenase activity
BXO512_000490	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BXO512_000545	COG2814	Major facilitator Superfamily
BXO512_000550	COG1566	PFAM secretion protein HlyD family protein
BXO512_000565	COG2207	Transcriptional regulator
BXO512_000590	COG4774	siderophore transport
BXO512_000600	COG0367	asparagine synthase
BXO512_000615	COG1393	Belongs to the ArsC family
BXO512_000630	COG3039	Transposase
BXO512_000680	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BXO512_000695	COG0233	cytoplasmic translational termination
BXO512_000705	COG0575	Belongs to the CDS family
BXO512_000715	COG0750	zinc metalloprotease
BXO512_000730	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BXO512_000735	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BXO512_000755	COG0825	malonyl-CoA metabolic process
BXO512_000765	COG4771	TonB-dependent receptor
BXO512_000770	COG1131	(ABC) transporter
BXO512_000795	COG1981	membrane
BXO512_000840	COG2895	sulfate adenylyltransferase (ATP) activity
BXO512_000840	COG0529	Catalyzes the synthesis of activated sulfate
BXO512_000875	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BXO512_000890	COG2040	homocysteine
BXO512_000895	COG0833	amino acid
BXO512_000915	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BXO512_000915	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BXO512_000925	COG2878	Part of a membrane complex involved in electron transport
BXO512_000940	COG1595	DNA-templated transcription, initiation
BXO512_000965	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BXO512_000980	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BXO512_000985	COG0251	oxidation-reduction process
BXO512_000995	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BXO512_000995	COG0392	lysyltransferase activity
BXO512_001025	COG3039	Transposase
BXO512_001035	COG2814	Major facilitator Superfamily
BXO512_001040	COG1902	pentaerythritol trinitrate reductase activity
BXO512_001050	COG2824	Alkylphosphonate utilization operon protein PhnA
BXO512_001065	COG1047	Peptidyl-prolyl cis-trans
BXO512_001105	COG3039	Transposase
BXO512_001110	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BXO512_001125	COG1451	nucleotide metabolic process
BXO512_001145	COG0183	Belongs to the thiolase family
BXO512_001175	COG1793	dna ligase
BXO512_001175	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BXO512_001185	COG1793	dna ligase
BXO512_001190	COG1201	RNA secondary structure unwinding
BXO512_001210	COG1278	Cold shock
BXO512_001215	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BXO512_001220	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BXO512_001230	COG3046	protein related to deoxyribodipyrimidine photolyase
BXO512_001240	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BXO512_001265	COG3039	Transposase
BXO512_001275	COG2954	triphosphatase activity
BXO512_001290	COG1381	Involved in DNA repair and RecF pathway recombination
BXO512_001320	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BXO512_001335	COG1250	3-hydroxyacyl-CoA dehydrogenase
BXO512_001335	COG1024	Enoyl-CoA hydratase
BXO512_001355	COG1024	Enoyl-CoA hydratase
BXO512_001360	COG1960	acyl-CoA dehydrogenase activity
BXO512_001430	COG2353	YceI-like domain
BXO512_001440	COG2353	YceI-like domain
BXO512_001455	COG1760	l-serine dehydratase
BXO512_001465	COG0626	cystathionine gamma-synthase activity
BXO512_001470	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BXO512_001475	COG0739	heme binding
BXO512_001485	COG1272	protein, Hemolysin III
BXO512_001505	COG0463	Glycosyl transferase, family 2
BXO512_001515	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BXO512_001525	COG4771	TonB-dependent receptor
BXO512_001530	COG1309	transcriptional regulator
BXO512_001540	COG1960	acyl-CoA dehydrogenase activity
BXO512_001570	COG0509	glycine decarboxylation via glycine cleavage system
BXO512_001585	COG0330	HflC and HflK could
BXO512_001600	COG3956	TIGRFAM MazG family protein
BXO512_001610	COG0494	nUDIX hydrolase
BXO512_001620	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BXO512_001625	COG0837	glucose binding
BXO512_001645	COG3858	chitin binding
BXO512_001645	COG1388	LysM domain
BXO512_001655	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BXO512_001665	COG1472	Belongs to the glycosyl hydrolase 3 family
BXO512_001705	COG3537	Alpha-1,2-mannosidase
BXO512_001745	COG3142	Participates in the control of copper homeostasis
BXO512_001750	COG1446	asparaginase
BXO512_001775	COG3039	Transposase
BXO512_001795	COG0643	Histidine kinase
BXO512_001795	COG0784	Response regulator, receiver
BXO512_001795	COG2198	Histidine kinase
BXO512_001800	COG0840	transmembrane signaling receptor activity
BXO512_001805	COG0835	chemotaxis
BXO512_001820	COG0189	ligase activity
BXO512_001830	COG1397	ADP-ribosylglycohydrolase
BXO512_001840	COG1199	ATP-dependent helicase activity
BXO512_001850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BXO512_001855	COG1215	transferase activity, transferring glycosyl groups
BXO512_001865	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BXO512_001885	COG0535	radical SAM domain protein
BXO512_001890	COG0535	radical SAM domain protein
BXO512_001915	COG1643	Atp-dependent helicase
BXO512_001920	COG0783	Belongs to the Dps family
BXO512_001925	COG0514	ATP-dependent DNA helicase (RecQ)
BXO512_001945	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BXO512_001995	COG1187	pseudouridine synthase activity
BXO512_002000	COG0602	queuosine metabolic process
BXO512_002010	COG2885	chlorophyll binding
BXO512_002025	COG0848	biopolymer transport protein
BXO512_002035	COG0824	Thioesterase
BXO512_002040	COG2255	four-way junction helicase activity
BXO512_002050	COG0632	four-way junction helicase activity
BXO512_002180	COG3209	COG3209 Rhs family protein
BXO512_002200	COG3209	COG3209 Rhs family protein
BXO512_002200	COG3209	COG3209 Rhs family protein
BXO512_002220	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BXO512_002225	COG1845	cytochrome c oxidase, subunit III
BXO512_002230	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BXO512_002245	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BXO512_002250	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BXO512_002260	COG0196	riboflavin kinase activity
BXO512_002265	COG0728	peptidoglycan biosynthetic process
BXO512_002270	COG0268	Binds directly to 16S ribosomal RNA
BXO512_002275	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BXO512_002280	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BXO512_002290	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BXO512_002295	COG0824	Thioesterase
BXO512_002310	COG1946	Acyl-CoA thioesterase
BXO512_002320	COG1595	DNA-templated transcription, initiation
BXO512_002335	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BXO512_002375	COG1877	trehalose-phosphatase activity
BXO512_002380	COG3387	PFAM Glycoside hydrolase 15-related
BXO512_002405	COG0564	pseudouridine synthase activity
BXO512_002410	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BXO512_002415	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BXO512_002415	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BXO512_002430	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BXO512_002435	COG0045	succinate-CoA ligase (ADP-forming) activity
BXO512_002475	COG2194	sulfuric ester hydrolase activity
BXO512_002480	COG4969	Belongs to the N-Me-Phe pilin family
BXO512_002490	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BXO512_002510	COG3039	Transposase
BXO512_002560	COG1132	(ABC) transporter
BXO512_002590	COG0745	RESPONSE REGULATOR receiver
BXO512_002595	COG5000	phosphorelay sensor kinase activity
BXO512_002595	COG5002	protein histidine kinase activity
BXO512_002600	COG0475	glutathione-regulated potassium exporter activity
BXO512_002610	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BXO512_002630	COG1187	pseudouridine synthase activity
BXO512_002635	COG5002	protein histidine kinase activity
BXO512_002635	COG5001	Diguanylate cyclase
BXO512_002735	COG1028	Short-chain dehydrogenase reductase Sdr
BXO512_002750	COG0415	Belongs to the DNA photolyase family
BXO512_002755	COG0305	Participates in initiation and elongation during chromosome replication
BXO512_002765	COG0367	asparagine synthase
BXO512_002780	COG1960	acyl-CoA dehydrogenase activity
BXO512_002795	COG0084	hydrolase, TatD family'
BXO512_002800	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BXO512_002860	COG0735	belongs to the Fur family
BXO512_002865	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BXO512_002885	COG3039	Transposase
BXO512_002895	COG3039	Transposase
BXO512_002900	COG3039	Transposase
BXO512_002950	COG2205	protein histidine kinase activity
BXO512_002960	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BXO512_002970	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BXO512_002985	COG2198	Histidine kinase
BXO512_002985	COG0643	Histidine kinase
BXO512_002990	COG0840	transmembrane signaling receptor activity
BXO512_002995	COG0835	chemotaxis
BXO512_003000	COG2202	Pas domain
BXO512_003000	COG2200	EAL domain
BXO512_003000	COG2199	diguanylate cyclase activity
BXO512_003005	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BXO512_003045	COG0588	phosphoglycerate mutase activity
BXO512_003050	COG1515	deoxyribonuclease V activity
BXO512_003060	COG1741	Belongs to the pirin family
BXO512_003125	COG1741	Belongs to the pirin family
BXO512_003130	COG1966	Carbon starvation protein
BXO512_003135	COG2879	small protein
BXO512_003175	COG4251	negative regulation of phosphorylation
BXO512_003175	COG5001	Diguanylate cyclase
BXO512_003175	COG3706	GGDEF domain
BXO512_003175	COG2203	Gaf domain
BXO512_003180	COG0629	single-stranded DNA binding
BXO512_003185	COG0142	geranyltranstransferase activity
BXO512_003215	COG0527	aspartate kinase activity
BXO512_003225	COG0384	phenazine biosynthesis protein PhzF
BXO512_003235	COG1764	response to oxidative stress
BXO512_003250	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BXO512_003255	COG1678	Uncharacterized ACR, COG1678
BXO512_003265	COG0519	Catalyzes the synthesis of GMP from XMP
BXO512_003295	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BXO512_003335	COG0693	protein deglycase activity
BXO512_003355	COG1959	2 iron, 2 sulfur cluster binding
BXO512_003360	COG0719	Fe-S assembly protein
BXO512_003365	COG0396	ATPase activity
BXO512_003370	COG0719	Fe-S assembly protein
BXO512_003375	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BXO512_003385	COG2146	nitrite reductase [NAD(P)H] activity
BXO512_003410	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BXO512_003425	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BXO512_003435	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BXO512_003440	COG0174	glutamine synthetase
BXO512_003445	COG3328	transposase activity
BXO512_003470	COG0326	Molecular chaperone. Has ATPase activity
BXO512_003475	COG2207	Transcriptional regulator
BXO512_003505	COG2755	lipolytic protein G-D-S-L family
BXO512_003505	COG0657	acetylesterase activity
BXO512_003530	COG0488	(ABC) transporter
BXO512_003565	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BXO512_003565	COG4651	solute:proton antiporter activity
BXO512_003580	COG4772	TonB-dependent receptor
BXO512_003590	COG4264	IucA IucC family
BXO512_003595	COG2814	Major facilitator Superfamily
BXO512_003605	COG0019	diaminopimelate decarboxylase activity
BXO512_003665	COG4206	TonB-dependent receptor
BXO512_003700	COG0542	response to heat
BXO512_003740	COG0534	Mate efflux family protein
BXO512_003755	COG0336	Belongs to the RNA methyltransferase TrmD family
BXO512_003760	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BXO512_003765	COG0228	four-way junction DNA binding
BXO512_003785	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BXO512_003795	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BXO512_003840	COG1555	photosystem II stabilization
BXO512_003845	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BXO512_003860	COG3178	'Phosphotransferase
BXO512_003865	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BXO512_003875	COG0628	permease
BXO512_003885	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BXO512_003900	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BXO512_003925	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BXO512_003930	COG0271	Belongs to the BolA IbaG family
BXO512_003940	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BXO512_003950	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BXO512_003955	COG1137	ATPase activity
BXO512_003970	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BXO512_003975	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BXO512_003980	COG1660	Displays ATPase and GTPase activities
BXO512_003995	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BXO512_004000	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BXO512_004005	COG2239	Acts as a magnesium transporter
BXO512_004015	COG1294	oxidase, subunit
BXO512_004020	COG1271	oxidase subunit
BXO512_004035	COG1113	amino acid transport
BXO512_004050	COG2197	response regulator
BXO512_004055	COG0531	amino acid
BXO512_004110	COG0754	glutathionylspermidine amidase activity
BXO512_004135	COG1842	Phage shock protein A
BXO512_004150	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BXO512_004155	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BXO512_004165	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BXO512_004235	COG2801	Transposase and inactivated derivatives
BXO512_004250	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BXO512_004300	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BXO512_004305	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BXO512_004330	COG3039	Transposase
BXO512_004345	COG0745	RESPONSE REGULATOR receiver
BXO512_004350	COG2205	protein histidine kinase activity
BXO512_004370	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BXO512_004400	COG3453	Protein conserved in bacteria
BXO512_004400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BXO512_004405	COG0725	ABC transporter, periplasmic molybdate-binding protein
BXO512_004410	COG4149	molybdate abc transporter
BXO512_004415	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BXO512_004435	COG0642	Histidine kinase
BXO512_004450	COG1028	Short-chain dehydrogenase reductase Sdr
BXO512_004460	COG1022	Amp-dependent synthetase and ligase
BXO512_004485	COG1376	ErfK ybiS ycfS ynhG family protein
BXO512_004490	COG0739	heme binding
BXO512_004500	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BXO512_004505	COG1301	dicarboxylic acid transport
BXO512_004525	COG2304	oxidoreductase activity
BXO512_004545	COG0714	Associated with various cellular activities
BXO512_004590	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BXO512_004615	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BXO512_004625	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BXO512_004650	COG1561	YicC-like family, N-terminal region
BXO512_004655	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BXO512_004670	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BXO512_004705	COG0006	proline dipeptidase activity
BXO512_004730	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BXO512_004740	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BXO512_004750	COG2912	Transglutaminase-like superfamily
BXO512_004755	COG1773	rubredoxin
BXO512_004760	COG0352	thiamine-phosphate diphosphorylase activity
BXO512_004830	COG0281	malic enzyme
BXO512_004830	COG0280	phosphate acetyltransferase
BXO512_004850	COG4191	Histidine kinase
BXO512_004865	COG0583	DNA-binding transcription factor activity
BXO512_004880	COG2197	response regulator
BXO512_004890	COG0642	Histidine kinase
BXO512_004905	COG2851	Citrate transporter
BXO512_004910	COG1028	Short-chain dehydrogenase reductase Sdr
BXO512_004915	COG1609	Transcriptional regulator
BXO512_004925	COG2211	Major facilitator Superfamily
BXO512_004950	COG1162	GTPase activity
BXO512_004975	COG0726	polysaccharide deacetylase
BXO512_004980	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BXO512_005005	COG3039	Transposase
BXO512_005010	COG3039	Transposase
BXO512_005055	COG0242	peptide deformylase activity
BXO512_005075	COG0714	Associated with various cellular activities
BXO512_005095	COG0537	adenosine 5'-monophosphoramidase activity
BXO512_005125	COG0314	molybdopterin synthase activity
BXO512_005130	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BXO512_005135	COG0315	cyclic pyranopterin monophosphate synthase activity
BXO512_005145	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BXO512_005150	COG1234	tRNA 3'-trailer cleavage
BXO512_005155	COG3642	lipopolysaccharide core region biosynthetic process
BXO512_005160	COG0859	PFAM glycosyl transferase family 9
BXO512_005170	COG0582	viral genome integration into host DNA
BXO512_005225	COG0631	protein serine/threonine phosphatase activity
BXO512_005235	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BXO512_005260	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BXO512_005300	COG0544	peptidyl-prolyl cis-trans isomerase activity
BXO512_005350	COG0473	3-isopropylmalate dehydrogenase activity
BXO512_005375	COG4783	chaperone-mediated protein folding
BXO512_005390	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BXO512_005400	COG0438	transferase activity, transferring glycosyl groups
BXO512_005405	COG0671	phosphoesterase, PA-phosphatase related
BXO512_005410	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BXO512_005430	COG2833	Protein of unknown function (DUF455)
BXO512_005450	COG0285	dihydrofolate synthase activity
BXO512_005460	COG0588	phosphoglycerate mutase activity
BXO512_005490	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BXO512_005495	COG4208	sulfate ABC transporter
BXO512_005500	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BXO512_005505	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BXO512_005510	COG0156	8-amino-7-oxononanoate synthase activity
BXO512_005535	COG0604	alcohol dehydrogenase
BXO512_005540	COG0446	pyridine nucleotide-disulphide oxidoreductase
BXO512_005540	COG1902	pentaerythritol trinitrate reductase activity
BXO512_005630	COG0697	spore germination
BXO512_005660	COG3386	PFAM SMP-30 Gluconolaconase
BXO512_005680	COG1024	Enoyl-CoA hydratase
BXO512_005690	COG0318	PFAM AMP-dependent synthetase and ligase
BXO512_005695	COG0583	DNA-binding transcription factor activity
BXO512_005735	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BXO512_005740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BXO512_005750	COG2096	Adenosyltransferase
BXO512_005755	COG0123	including yeast histone deacetylase and acetoin utilization protein
BXO512_005770	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BXO512_005780	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BXO512_005785	COG2967	ApaG domain
BXO512_005810	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BXO512_005830	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BXO512_005860	COG0642	Histidine kinase
BXO512_005875	COG4181	ATPase activity
BXO512_005885	COG2175	clavaminate synthase activity
BXO512_005940	COG0667	Aldo Keto reductase
BXO512_005950	COG3039	Transposase
BXO512_005960	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BXO512_005965	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BXO512_005975	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BXO512_005990	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BXO512_006035	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BXO512_006040	COG2226	methyltransferase
BXO512_006085	COG1028	Short-chain dehydrogenase reductase Sdr
BXO512_006085	COG0604	alcohol dehydrogenase
BXO512_006085	COG3321	synthase
BXO512_006095	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BXO512_006110	COG0494	nUDIX hydrolase
BXO512_006125	COG4942	peptidase
BXO512_006125	COG1388	LysM domain
BXO512_006135	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BXO512_006150	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BXO512_006155	COG1181	Belongs to the D-alanine--D-alanine ligase family
BXO512_006160	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BXO512_006175	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BXO512_006180	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BXO512_006195	COG3116	cell division
BXO512_006200	COG0275	rRNA processing
BXO512_006235	COG0792	nuclease activity
BXO512_006240	COG1988	membrane-bound metal-dependent
BXO512_006245	COG0277	FAD linked oxidase domain protein
BXO512_006250	COG0745	RESPONSE REGULATOR receiver
BXO512_006255	COG2205	protein histidine kinase activity
BXO512_006265	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BXO512_006270	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BXO512_006290	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BXO512_006295	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BXO512_006300	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BXO512_006320	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BXO512_006320	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BXO512_006340	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BXO512_006360	COG0488	(ABC) transporter
BXO512_006410	COG2205	protein histidine kinase activity
BXO512_006460	COG2205	protein histidine kinase activity
BXO512_006475	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BXO512_006510	COG3039	Transposase
BXO512_006525	COG3039	Transposase
BXO512_006610	COG1649	PFAM Uncharacterised BCR, COG1649
BXO512_006610	COG0726	polysaccharide deacetylase
BXO512_006615	COG1215	transferase activity, transferring glycosyl groups
BXO512_006625	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BXO512_006630	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BXO512_006635	COG1609	Transcriptional regulator
BXO512_006645	COG2188	Transcriptional regulator
BXO512_006660	COG3250	beta-galactosidase activity
BXO512_006710	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BXO512_006715	COG4191	Histidine kinase
BXO512_006720	COG0784	Response regulator, receiver
BXO512_006725	COG4251	negative regulation of phosphorylation
BXO512_006730	COG2823	Periplasmic or secreted lipoprotein
BXO512_006735	COG0673	inositol 2-dehydrogenase activity
BXO512_006740	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BXO512_006775	COG1056	cytidyltransferase-related domain
BXO512_006775	COG1051	belongs to the nudix hydrolase family
BXO512_006800	COG2921	Belongs to the UPF0250 family
BXO512_006815	COG1686	Belongs to the peptidase S11 family
BXO512_006820	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BXO512_006825	COG2951	lytic endotransglycosylase activity
BXO512_006895	COG0772	Belongs to the SEDS family
BXO512_006910	COG1792	Involved in formation and maintenance of cell shape
BXO512_006915	COG1077	Cell shape determining protein MreB Mrl
BXO512_006920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BXO512_006970	COG2199	diguanylate cyclase activity
BXO512_006975	COG0308	aminopeptidase N
BXO512_007005	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BXO512_007035	COG0436	Aminotransferase
BXO512_007040	COG3039	Transposase
BXO512_007060	COG1505	serine-type exopeptidase activity
BXO512_007085	COG0181	hydroxymethylbilane synthase activity
BXO512_007095	COG3275	phosphorelay sensor kinase activity
BXO512_007130	COG0659	secondary active sulfate transmembrane transporter activity
BXO512_007135	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BXO512_007135	COG5297	Belongs to the glycosyl hydrolase family 6
BXO512_007210	COG0598	Magnesium transport protein CorA
BXO512_007220	COG1113	amino acid transport
BXO512_007230	COG5297	Belongs to the glycosyl hydrolase family 6
BXO512_007235	COG4305	rare lipoprotein A
BXO512_007240	COG0697	spore germination
BXO512_007300	COG4221	oxidoreductase activity
BXO512_007330	COG0456	acetyltransferase
BXO512_007340	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BXO512_007385	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BXO512_007385	COG2111	Na H antiporter
BXO512_007390	COG1006	Multisubunit Na H antiporter MnhC subunit
BXO512_007395	COG0651	ATP synthesis coupled electron transport
BXO512_007405	COG2212	antiporter activity
BXO512_007410	COG1320	monovalent cation:proton antiporter activity
BXO512_007420	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BXO512_007440	COG3104	oligopeptide transport
BXO512_007445	COG3483	tryptophan 2,3-dioxygenase activity
BXO512_007455	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BXO512_007495	COG0183	Belongs to the thiolase family
BXO512_007565	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
BXO512_007570	COG3023	N-Acetylmuramoyl-L-alanine amidase
BXO512_007580	COG4948	Mandelate Racemase Muconate Lactonizing
BXO512_007605	COG0531	amino acid
BXO512_007630	COG4682	membrane
BXO512_007635	COG2133	pyrroloquinoline quinone binding
BXO512_007675	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BXO512_007680	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BXO512_007690	COG1610	YqeY-like protein
BXO512_007700	COG1295	ribonuclease BN
BXO512_007705	COG0358	DNA primase activity
BXO512_007770	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
BXO512_007785	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BXO512_007835	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BXO512_007840	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BXO512_007845	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
BXO512_007855	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BXO512_007860	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BXO512_007870	COG0134	indole-3-glycerol-phosphate synthase activity
BXO512_007875	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BXO512_007935	COG3039	Transposase
BXO512_007965	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BXO512_007965	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BXO512_007975	COG1473	amidohydrolase
BXO512_007980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BXO512_007985	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BXO512_007995	COG5383	Protein conserved in bacteria
BXO512_008030	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BXO512_008035	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BXO512_008050	COG0028	Belongs to the TPP enzyme family
BXO512_008060	COG4191	Histidine kinase
BXO512_008085	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BXO512_008100	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BXO512_008105	COG3177	Filamentation induced by cAMP protein fic
BXO512_008120	COG0596	Alpha beta hydrolase
BXO512_008125	COG0727	PFAM Uncharacterised protein family (UPF0153)
BXO512_008130	COG0318	PFAM AMP-dependent synthetase and ligase
BXO512_008135	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BXO512_008185	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BXO512_008195	COG0129	dihydroxy-acid dehydratase activity
BXO512_008215	COG3039	Transposase
BXO512_008225	COG0408	coproporphyrinogen oxidase activity
BXO512_008265	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BXO512_008325	COG2353	YceI-like domain
BXO512_008355	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BXO512_008370	COG3386	PFAM SMP-30 Gluconolaconase
BXO512_008405	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BXO512_008425	COG0459	protein refolding
BXO512_008455	COG1252	NADH dehydrogenase
BXO512_008465	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BXO512_008470	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BXO512_008475	COG2201	protein-glutamate methylesterase activity
BXO512_008480	COG2177	Part of the ABC transporter FtsEX involved in
BXO512_008485	COG2884	Cell division ATP-binding protein ftsE
BXO512_008495	COG3118	belongs to the thioredoxin family
BXO512_008500	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BXO512_008515	COG0729	surface antigen
BXO512_008520	COG2911	Protein conserved in bacteria
BXO512_008555	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BXO512_008570	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BXO512_008620	COG1733	regulation of RNA biosynthetic process
BXO512_008625	COG0702	epimerase
BXO512_008655	COG0583	DNA-binding transcription factor activity
BXO512_008660	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BXO512_008680	COG0745	RESPONSE REGULATOR receiver
BXO512_008710	COG1902	pentaerythritol trinitrate reductase activity
BXO512_008715	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BXO512_008725	COG2814	Major facilitator Superfamily
BXO512_008730	COG0583	DNA-binding transcription factor activity
BXO512_008745	COG0084	hydrolase, TatD family'
BXO512_008790	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BXO512_008810	COG2072	flavoprotein involved in K transport
BXO512_008870	COG4770	biotin carboxylase activity
BXO512_008875	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BXO512_008880	COG1960	acyl-CoA dehydrogenase activity
BXO512_008930	COG0523	cobalamin synthesis protein
BXO512_008940	COG0697	spore germination
BXO512_008950	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BXO512_008965	COG4771	TonB-dependent receptor
BXO512_008970	COG0457	Tetratricopeptide repeat
BXO512_008980	COG0752	glycyl-tRNA synthetase alpha subunit
BXO512_008985	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BXO512_009000	COG0519	Catalyzes the synthesis of GMP from XMP
BXO512_009000	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BXO512_009010	COG0805	protein transport
BXO512_009020	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BXO512_009030	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BXO512_009055	COG2974	May be involved in recombination
BXO512_009060	COG0037	tRNA processing
BXO512_009075	COG3661	Belongs to the glycosyl hydrolase 67 family
BXO512_009085	COG4948	Mandelate Racemase Muconate Lactonizing
BXO512_009095	COG1472	Belongs to the glycosyl hydrolase 3 family
BXO512_009100	COG0246	Mannitol dehydrogenase
BXO512_009125	COG3693	PFAM glycoside hydrolase, family 10
BXO512_009145	COG2211	Major facilitator Superfamily
BXO512_009190	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BXO512_009230	COG1846	Transcriptional regulator
BXO512_009235	COG1764	response to oxidative stress
BXO512_009310	COG3549	Plasmid maintenance system killer
BXO512_009320	COG1074	ATP-dependent DNA helicase activity
BXO512_009325	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BXO512_009370	COG2032	superoxide dismutase activity
BXO512_009375	COG2032	superoxide dismutase activity
BXO512_009380	COG2204	response regulator
BXO512_009385	COG3852	Histidine kinase
BXO512_009390	COG0004	ammonium transporteR
BXO512_009395	COG0347	Belongs to the P(II) protein family
BXO512_009400	COG0174	glutamine synthetase
BXO512_009405	COG1968	undecaprenyl-diphosphatase activity
BXO512_009455	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BXO512_009465	COG2062	phosphohistidine phosphatase, SixA
BXO512_009470	COG0489	protein tyrosine kinase activity
BXO512_009490	COG1396	sequence-specific DNA binding
BXO512_009495	COG3550	peptidyl-serine autophosphorylation
BXO512_009500	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
BXO512_009505	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BXO512_009520	COG0517	IMP dehydrogenase activity
BXO512_009520	COG1125	glycine betaine transport
BXO512_009535	COG1119	ATPase activity
BXO512_009545	COG1752	Esterase of the alpha-beta hydrolase superfamily
BXO512_009585	COG0656	L-ascorbic acid biosynthetic process
BXO512_009590	COG2130	NADP-dependent
BXO512_009595	COG0667	Aldo Keto reductase
BXO512_009605	COG1187	pseudouridine synthase activity
BXO512_009615	COG1643	Atp-dependent helicase
BXO512_009620	COG4807	Protein conserved in bacteria
BXO512_009625	COG4948	Mandelate Racemase Muconate Lactonizing
BXO512_009630	COG0179	Fumarylacetoacetate (FAA) hydrolase
BXO512_009635	COG1028	Short-chain dehydrogenase reductase Sdr
BXO512_009655	COG3507	Belongs to the glycosyl hydrolase 43 family
BXO512_009695	COG3162	membrane
BXO512_009700	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BXO512_009715	COG0708	Exodeoxyribonuclease III
BXO512_009730	COG2091	lysine biosynthetic process via aminoadipic acid
BXO512_009740	COG3540	Alkaline phosphatase
BXO512_009745	COG0357	Ribosomal RNA small subunit methyltransferase G
BXO512_009775	COG2159	amidohydrolase
BXO512_009785	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BXO512_009790	COG0583	DNA-binding transcription factor activity
BXO512_009795	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BXO512_009810	COG0210	DNA helicase
BXO512_009825	COG0531	amino acid
BXO512_009830	COG1322	Protein conserved in bacteria
BXO512_009840	COG0386	Belongs to the glutathione peroxidase family
BXO512_009895	COG0793	Belongs to the peptidase S41A family
BXO512_009900	COG4942	peptidase
BXO512_009910	COG2234	aminopeptidase activity
BXO512_009955	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BXO512_009960	COG0302	gtp cyclohydrolase
BXO512_009985	COG0477	Major facilitator Superfamily
BXO512_010050	COG1929	Belongs to the glycerate kinase type-1 family
BXO512_010055	COG2271	Major facilitator Superfamily
BXO512_010070	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BXO512_010075	COG0861	Integral membrane protein TerC family
BXO512_010090	COG0584	glycerophosphoryl diester phosphodiesterase
BXO512_010100	COG0671	phosphoesterase, PA-phosphatase related
BXO512_010105	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BXO512_010110	COG0726	polysaccharide deacetylase
BXO512_010130	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BXO512_010145	COG0187	DNA topoisomerase II activity
BXO512_010155	COG0501	Belongs to the peptidase M48B family
BXO512_010185	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BXO512_010195	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BXO512_010210	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BXO512_010220	COG4772	TonB-dependent receptor
BXO512_010235	COG3039	Transposase
BXO512_010240	COG1304	FMN binding
BXO512_010260	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BXO512_010275	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BXO512_010345	COG3039	Transposase
BXO512_010365	COG2826	transposase and inactivated derivatives, IS30 family
BXO512_010390	COG3039	Transposase
BXO512_010400	COG1090	epimerase
BXO512_010410	COG0642	Histidine kinase
BXO512_010420	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BXO512_010530	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BXO512_010605	COG3264	Mechanosensitive ion channel
BXO512_010605	COG1511	domain protein
BXO512_010620	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BXO512_010625	COG2354	Protein conserved in bacteria
BXO512_010630	COG1649	PFAM Uncharacterised BCR, COG1649
BXO512_010650	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BXO512_010675	COG0702	epimerase
BXO512_010690	COG1858	cytochrome C peroxidase
BXO512_010770	COG0513	Belongs to the DEAD box helicase family
BXO512_010775	COG3039	Transposase
BXO512_010820	COG1136	(ABC) transporter
BXO512_010855	COG1136	(ABC) transporter
BXO512_010895	COG1272	protein, Hemolysin III
BXO512_010900	COG1205	dead DEAH box helicase
BXO512_010900	COG1111	helicase
BXO512_010960	COG0067	glutamate synthase
BXO512_010960	COG0069	glutamate synthase activity
BXO512_010960	COG0070	glutamate synthase
BXO512_010965	COG0493	'glutamate synthase
BXO512_011010	COG1609	Transcriptional regulator
BXO512_011040	COG0366	Alpha amylase catalytic
BXO512_011045	COG0366	Alpha amylase catalytic
BXO512_011090	COG0606	chelatase, subunit chli
BXO512_011130	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BXO512_011135	COG1166	arginine decarboxylase activity
BXO512_011200	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BXO512_011225	COG1028	Short-chain dehydrogenase reductase Sdr
BXO512_011250	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
BXO512_011270	COG0210	DNA helicase
BXO512_011285	COG3132	Protein of unknown function, DUF480
BXO512_011290	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BXO512_011295	COG0284	orotidine-5'-phosphate decarboxylase activity
BXO512_011330	COG2937	Belongs to the GPAT DAPAT family
BXO512_011370	COG3186	Phenylalanine-4-hydroxylase
BXO512_011375	COG1522	sequence-specific DNA binding
BXO512_011420	COG1064	alcohol dehydrogenase
BXO512_011425	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BXO512_011435	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BXO512_011445	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BXO512_011465	COG0676	glucose-6-phosphate 1-epimerase activity
BXO512_011530	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BXO512_011555	COG2853	Lipoprotein
BXO512_011570	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BXO512_011575	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BXO512_011580	COG1127	ABC transporter
BXO512_011655	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BXO512_011665	COG3039	Transposase
BXO512_011670	COG3265	gluconokinase activity
BXO512_011675	COG2211	Major facilitator Superfamily
BXO512_011680	COG3459	Glycosyltransferase 36 associated
BXO512_011690	COG2205	protein histidine kinase activity
BXO512_011700	COG1414	Transcriptional regulator
BXO512_011705	COG0738	Major facilitator superfamily
BXO512_011710	COG3254	rhamnose metabolic process
BXO512_011740	COG0339	signal peptide processing
BXO512_011770	COG0564	pseudouridine synthase activity
BXO512_011780	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BXO512_011790	COG1181	Belongs to the D-alanine--D-alanine ligase family
BXO512_011855	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BXO512_011865	COG0842	Transport permease protein
BXO512_011870	COG1131	(ABC) transporter
BXO512_011900	COG1476	TRANSCRIPTIONal
BXO512_011910	COG4555	ABC transporter
BXO512_011945	COG0625	glutathione transferase activity
BXO512_011990	COG0583	DNA-binding transcription factor activity
BXO512_012030	COG1199	ATP-dependent helicase activity
BXO512_012050	COG1566	PFAM secretion protein HlyD family protein
BXO512_012070	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BXO512_012110	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BXO512_012110	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BXO512_012115	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BXO512_012130	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BXO512_012165	COG3237	CsbD-like
BXO512_012170	COG0180	Tryptophanyl-tRNA synthetase
BXO512_012175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BXO512_012220	COG0753	catalase activity
BXO512_012235	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BXO512_012245	COG0628	permease
BXO512_012255	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BXO512_012260	COG1040	competence protein
BXO512_012265	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BXO512_012270	COG0156	8-amino-7-oxononanoate synthase activity
BXO512_012280	COG1028	Short-chain dehydrogenase reductase Sdr
BXO512_012295	COG0463	Glycosyl transferase, family 2
BXO512_012305	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BXO512_012310	COG3100	YcgL domain-containing protein
BXO512_012325	COG3387	PFAM Glycoside hydrolase 15-related
BXO512_012330	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BXO512_012345	COG2239	Acts as a magnesium transporter
BXO512_012355	COG0045	succinate-CoA ligase (ADP-forming) activity
BXO512_012355	COG1042	CoA-binding domain protein
BXO512_012355	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BXO512_012365	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BXO512_012370	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BXO512_012405	COG3485	protocatechuate 3,4-dioxygenase
BXO512_012425	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BXO512_012430	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BXO512_012455	COG4221	oxidoreductase activity
BXO512_012480	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BXO512_012505	COG0463	Glycosyl transferase, family 2
BXO512_012520	COG1475	DNA binding
BXO512_012525	COG1192	Involved in chromosome partitioning
BXO512_012540	COG0708	Exodeoxyribonuclease III
BXO512_012545	COG2211	Major facilitator Superfamily
BXO512_012560	COG0739	heme binding
BXO512_012605	COG0745	RESPONSE REGULATOR receiver
BXO512_012645	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BXO512_012660	COG2814	Major facilitator Superfamily
BXO512_012675	COG1289	transmembrane transporter activity
BXO512_012700	COG0151	Belongs to the GarS family
BXO512_012710	COG0138	bifunctional purine biosynthesis protein purh
BXO512_012720	COG2267	carboxylic ester hydrolase activity
BXO512_012730	COG2267	carboxylic ester hydrolase activity
BXO512_012750	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BXO512_012795	COG0439	Biotin carboxylase
BXO512_012805	COG0511	ligase activity, forming carbon-carbon bonds
BXO512_012810	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BXO512_012820	COG1324	tolerance protein
BXO512_012855	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BXO512_012880	COG0534	Mate efflux family protein
BXO512_012885	COG0616	signal peptide processing
BXO512_012895	COG1028	Short-chain dehydrogenase reductase Sdr
BXO512_012910	COG0009	L-threonylcarbamoyladenylate synthase
BXO512_012915	COG1754	DNA topoisomerase type I activity
BXO512_012915	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BXO512_012930	COG2922	Belongs to the Smg family
BXO512_012935	COG0758	DNA mediated transformation
BXO512_012940	COG1652	LysM domain
BXO512_012945	COG0242	peptide deformylase activity
BXO512_012950	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BXO512_012955	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BXO512_012955	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BXO512_013005	COG1560	Kdo2-lipid A biosynthetic process
BXO512_013015	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BXO512_013160	COG3039	Transposase
BXO512_013170	COG1271	oxidase subunit
BXO512_013225	COG2972	Histidine kinase
BXO512_013240	COG0531	amino acid
BXO512_013260	COG3590	peptidase
BXO512_013270	COG0667	Aldo Keto reductase
BXO512_013285	COG3384	dioxygenase
BXO512_013295	COG1573	uracil-dna glycosylase
BXO512_013305	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
BXO512_013315	COG0025	NhaP-type Na H and K H
BXO512_013320	COG1131	(ABC) transporter
BXO512_013325	COG0842	Transport permease protein
BXO512_013340	COG1404	Belongs to the peptidase S8 family
BXO512_013355	COG0745	RESPONSE REGULATOR receiver
BXO512_013405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BXO512_013430	COG2205	protein histidine kinase activity
BXO512_013430	COG2202	Pas domain
BXO512_013460	COG2813	Specifically methylates the guanine in position
BXO512_013465	COG1187	pseudouridine synthase activity
BXO512_013470	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BXO512_013505	COG0697	spore germination
BXO512_013515	COG2011	ABC-type metal ion transport system permease component
BXO512_013545	COG0508	dehydrogenase complex catalyzes the overall conversion of
BXO512_013555	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BXO512_013575	COG0356	it plays a direct role in the translocation of protons across the membrane
BXO512_013585	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BXO512_013595	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BXO512_013600	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BXO512_013605	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BXO512_013610	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BXO512_013660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BXO512_013665	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BXO512_013715	COG0339	signal peptide processing
BXO512_013750	COG1956	GAF domain-containing protein
BXO512_013755	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BXO512_013765	COG0720	synthase
BXO512_013770	COG0513	Belongs to the DEAD box helicase family
BXO512_013780	COG0625	glutathione transferase activity
BXO512_013810	COG0626	cystathionine gamma-synthase activity
BXO512_013850	COG3328	transposase activity
BXO512_013875	COG2086	electron transfer activity
BXO512_013900	COG0662	Cupin 2, conserved barrel domain protein
BXO512_013900	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BXO512_013905	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BXO512_013940	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BXO512_013940	COG3218	ABC-type transport auxiliary lipoprotein component
BXO512_013945	COG1127	ABC transporter
BXO512_013950	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BXO512_013970	COG0442	prolyl-tRNA aminoacylation
BXO512_013980	COG1183	phosphatidylcholine synthase activity
BXO512_014045	COG3039	Transposase
BXO512_014075	COG0525	valine-tRNA ligase activity
BXO512_014090	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BXO512_014100	COG0795	lipopolysaccharide-transporting ATPase activity
BXO512_014115	COG4974	Belongs to the 'phage' integrase family
BXO512_014120	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BXO512_014130	COG5295	Hep Hag repeat protein
BXO512_014140	COG1404	Belongs to the peptidase S8 family
BXO512_014150	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BXO512_014160	COG1459	type II secretion system
BXO512_014165	COG2165	general secretion pathway protein
BXO512_014170	COG4970	Tfp pilus assembly protein FimT
BXO512_014175	COG2165	general secretion pathway protein
BXO512_014180	COG4795	General secretion pathway protein
BXO512_014185	COG3156	type II secretion system protein K
BXO512_014190	COG3166	PFAM Fimbrial assembly family protein
BXO512_014205	COG1450	Type ii and iii secretion system protein
BXO512_014220	COG2188	Transcriptional regulator
BXO512_014270	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BXO512_014275	COG1518	maintenance of DNA repeat elements
BXO512_014310	COG3039	Transposase
BXO512_014325	COG1399	metal-binding, possibly nucleic acid-binding protein
BXO512_014350	COG1028	Short-chain dehydrogenase reductase Sdr
BXO512_014355	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BXO512_014365	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BXO512_014370	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BXO512_014390	COG3039	Transposase
BXO512_014410	COG3829	transcription factor binding
BXO512_014485	COG2826	transposase and inactivated derivatives, IS30 family
BXO512_014495	COG0678	peroxiredoxin activity
BXO512_014515	COG0330	HflC and HflK could
BXO512_014520	COG0330	HflC and HflK could
BXO512_014530	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BXO512_014535	COG0308	aminopeptidase N
BXO512_014595	COG1560	Kdo2-lipid A biosynthetic process
BXO512_014600	COG1519	Transferase
BXO512_014605	COG1538	Outer membrane efflux protein
BXO512_014610	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BXO512_014640	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BXO512_014645	COG0066	3-isopropylmalate dehydratase activity
BXO512_014650	COG2226	methyltransferase
BXO512_014680	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BXO512_014690	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BXO512_014695	COG3710	Transcriptional regulator
BXO512_014720	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BXO512_014740	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BXO512_014775	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BXO512_014785	COG3781	membrane
BXO512_014920	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BXO512_014940	COG1217	gtp-binding protein TYPA
BXO512_014945	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BXO512_014950	COG0039	L-malate dehydrogenase activity
BXO512_014955	COG0625	glutathione transferase activity
BXO512_014970	COG3039	Transposase
BXO512_015005	COG0584	glycerophosphoryl diester phosphodiesterase
BXO512_015040	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BXO512_015075	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BXO512_015080	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BXO512_015085	COG0583	DNA-binding transcription factor activity
BXO512_015090	COG3634	alkyl hydroperoxide reductase activity
BXO512_015100	COG2890	protein-(glutamine-N5) methyltransferase activity
BXO512_015140	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BXO512_015140	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BXO512_015155	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BXO512_015180	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BXO512_015205	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BXO512_015215	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BXO512_015245	COG1295	ribonuclease BN
BXO512_015250	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BXO512_015270	COG0521	Mo-molybdopterin cofactor biosynthetic process
BXO512_015280	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BXO512_015285	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BXO512_015295	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BXO512_015310	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BXO512_015320	COG0193	aminoacyl-tRNA hydrolase activity
BXO512_015325	COG0012	GTP binding
BXO512_015355	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BXO512_015360	COG0250	Participates in transcription elongation, termination and antitermination
BXO512_015365	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BXO512_015375	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BXO512_015380	COG0222	ribosome binding
BXO512_015385	COG0085	RNA polymerase activity
BXO512_015390	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BXO512_015395	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BXO512_015400	COG0049	tRNA binding
BXO512_015420	COG0051	transcription antitermination factor activity, RNA binding
BXO512_015425	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BXO512_015430	COG0088	Forms part of the polypeptide exit tunnel
BXO512_015435	COG0089	rRNA binding
BXO512_015450	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BXO512_015460	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BXO512_015465	COG0255	Belongs to the universal ribosomal protein uL29 family
BXO512_015470	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BXO512_015475	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BXO512_015485	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BXO512_015515	COG1841	ribosomal large subunit assembly
BXO512_015525	COG0201	protein transport
BXO512_015535	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BXO512_015540	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BXO512_015550	COG0203	ribosomal protein L17
BXO512_015610	COG3551	Protein conserved in bacteria
BXO512_015640	COG2194	sulfuric ester hydrolase activity
BXO512_015650	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BXO512_015655	COG0745	RESPONSE REGULATOR receiver
BXO512_015660	COG0642	Histidine kinase
BXO512_015670	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BXO512_015675	COG2894	cell division
BXO512_015690	COG4585	Histidine kinase
BXO512_015695	COG2197	response regulator
BXO512_015710	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BXO512_015735	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BXO512_015740	COG2963	transposase activity
BXO512_015845	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BXO512_015855	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BXO512_015865	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BXO512_015910	COG3328	transposase activity
BXO512_015925	COG3179	chitinase
BXO512_016040	COG3039	Transposase
BXO512_016055	COG3039	Transposase
BXO512_016115	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
BXO512_016135	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BXO512_016140	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
BXO512_016145	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
BXO512_016160	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BXO512_016195	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BXO512_016200	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BXO512_016235	COG0587	DNA-directed DNA polymerase activity
BXO512_016250	COG1297	OPT oligopeptide transporter protein
BXO512_016270	COG1506	peptidase
BXO512_016270	COG0823	Involved in the tonB-independent uptake of proteins
BXO512_016290	COG2207	Transcriptional regulator
BXO512_016290	COG1917	Cupin 2, conserved barrel domain protein
BXO512_016315	COG0753	catalase activity
BXO512_016355	COG0469	pyruvate kinase activity
BXO512_016360	COG3588	fructose-bisphosphate aldolase
BXO512_016365	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BXO512_016415	COG0784	Response regulator, receiver
BXO512_016415	COG2198	Histidine kinase
BXO512_016415	COG2205	protein histidine kinase activity
BXO512_016435	COG0175	sulfate reduction
BXO512_016440	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BXO512_016445	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BXO512_016450	COG0175	sulfate reduction
BXO512_016455	COG0529	Catalyzes the synthesis of activated sulfate
BXO512_016455	COG2895	sulfate adenylyltransferase (ATP) activity
BXO512_016465	COG3039	Transposase
BXO512_016475	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BXO512_016480	COG0308	aminopeptidase N
BXO512_016500	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BXO512_016520	COG1970	mechanosensitive ion channel activity
BXO512_016550	COG0471	metal ion transport
BXO512_016550	COG3273	potassium ion transport
BXO512_016560	COG2022	thiamine diphosphate biosynthetic process
BXO512_016675	COG3118	belongs to the thioredoxin family
BXO512_016700	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BXO512_016725	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BXO512_016755	COG2968	Membrane
BXO512_016770	COG3164	Protein of unknown function
BXO512_016780	COG0312	modulator of DNA gyrase
BXO512_016785	COG3028	Belongs to the UPF0307 family
BXO512_016790	COG0312	modulator of DNA gyrase
BXO512_016815	COG0142	geranyltranstransferase activity
BXO512_016820	COG1722	exodeoxyribonuclease VII activity
BXO512_016825	COG0037	tRNA processing
BXO512_016830	COG1785	Belongs to the alkaline phosphatase family
BXO512_016835	COG1301	dicarboxylic acid transport
BXO512_016850	COG0791	NLP P60 protein
BXO512_016855	COG0791	NLP P60 protein
BXO512_016860	COG1047	Peptidyl-prolyl cis-trans
BXO512_016865	COG2311	Membrane
BXO512_016870	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BXO512_016910	COG0489	protein tyrosine kinase activity
BXO512_016915	COG0717	Belongs to the dCTP deaminase family
BXO512_016935	COG0412	Dienelactone hydrolase
BXO512_016945	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BXO512_016985	COG2890	protein-(glutamine-N5) methyltransferase activity
BXO512_016990	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BXO512_016995	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BXO512_017000	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BXO512_017020	COG0101	tRNA pseudouridine synthase activity
BXO512_017025	COG0135	phosphoribosylanthranilate isomerase activity
BXO512_017045	COG0159	tryptophan synthase activity
BXO512_017050	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BXO512_017055	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BXO512_017080	COG3293	Transposase
BXO512_017105	COG0149	triose-phosphate isomerase activity
BXO512_017120	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BXO512_017130	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BXO512_017135	COG0649	NAD binding
BXO512_017140	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BXO512_017145	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BXO512_017150	COG1034	ATP synthesis coupled electron transport
BXO512_017155	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BXO512_017185	COG1007	ATP synthesis coupled electron transport
BXO512_017195	COG0779	Required for maturation of 30S ribosomal subunits
BXO512_017200	COG0195	Participates in both transcription termination and antitermination
BXO512_017205	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BXO512_017220	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BXO512_017225	COG1185	polyribonucleotide nucleotidyltransferase activity
BXO512_017260	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BXO512_017270	COG2095	MarC family integral membrane protein
BXO512_017285	COG1611	Belongs to the LOG family
BXO512_017325	COG4969	Belongs to the N-Me-Phe pilin family
BXO512_017330	COG0556	nucleotide-excision repair
BXO512_017370	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BXO512_017385	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BXO512_017440	COG0438	transferase activity, transferring glycosyl groups
BXO512_017445	COG0438	transferase activity, transferring glycosyl groups
BXO512_017455	COG0438	transferase activity, transferring glycosyl groups
BXO512_017495	COG3040	lipid binding
BXO512_017575	COG4191	Histidine kinase
BXO512_017575	COG0784	Response regulator, receiver
BXO512_017595	COG0552	protein localization to endoplasmic reticulum
BXO512_017605	COG3938	Belongs to the proline racemase family
BXO512_017610	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BXO512_017625	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BXO512_017635	COG0006	proline dipeptidase activity
BXO512_017650	COG0531	amino acid
BXO512_017700	COG4206	TonB-dependent receptor
BXO512_017725	COG3328	transposase activity
BXO512_017785	COG0746	molybdenum cofactor guanylyltransferase activity
BXO512_017810	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BXO512_017810	COG1648	precorrin-2 dehydrogenase activity
BXO512_017850	COG3039	Transposase
BXO512_017855	COG3039	Transposase
BXO512_017885	COG3039	Transposase
BXO512_017900	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BXO512_017920	COG1054	Belongs to the UPF0176 family
BXO512_017935	COG1530	ribonuclease E activity
BXO512_017945	COG3064	Membrane
BXO512_017950	COG0428	transporter
BXO512_017955	COG0428	transporter
BXO512_017965	COG2154	pterin-4-alpha-carbinolamine dehydratase
BXO512_017970	COG0316	Belongs to the HesB IscA family
BXO512_017970	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BXO512_017995	COG3039	Transposase
BXO512_018020	COG3039	Transposase
BXO512_018150	COG0631	protein serine/threonine phosphatase activity
BXO512_018185	COG1858	cytochrome C peroxidase
BXO512_018240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BXO512_018245	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BXO512_018310	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BXO512_018330	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BXO512_018345	COG1595	DNA-templated transcription, initiation
BXO512_018395	COG2244	polysaccharide biosynthetic process
BXO512_018425	COG2264	protein methyltransferase activity
BXO512_018435	COG0438	transferase activity, transferring glycosyl groups
BXO512_018450	COG1136	(ABC) transporter
BXO512_018455	COG1132	(ABC) transporter
BXO512_018465	COG0477	Major facilitator Superfamily
BXO512_018475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BXO512_018490	COG1253	flavin adenine dinucleotide binding
BXO512_018500	COG0306	phosphate transporter
BXO512_018535	COG0504	CTP synthase activity
BXO512_018540	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BXO512_018550	COG0148	phosphopyruvate hydratase activity
BXO512_018555	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BXO512_018560	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BXO512_018570	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BXO512_018580	COG2840	Smr protein MutS2
BXO512_018585	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BXO512_018590	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BXO512_018595	COG1238	metal cluster binding
BXO512_018610	COG1534	Rna-binding protein
BXO512_018615	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BXO512_018625	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BXO512_018630	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BXO512_018640	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BXO512_018645	COG1546	Belongs to the CinA family
BXO512_018660	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BXO512_018665	COG2137	regulation of response to DNA damage stimulus
BXO512_018670	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BXO512_018675	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BXO512_018700	COG0305	Participates in initiation and elongation during chromosome replication
BXO512_018705	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BXO512_018730	COG1741	Belongs to the pirin family
BXO512_018735	COG0583	DNA-binding transcription factor activity
BXO512_018765	COG0351	phosphomethylpyrimidine kinase
BXO512_018775	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BXO512_018780	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BXO512_018800	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BXO512_018810	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BXO512_018815	COG3734	2-keto-3-deoxy-galactonokinase
BXO512_018825	COG4948	Mandelate Racemase Muconate Lactonizing
BXO512_018830	COG0800	Aldolase
BXO512_018845	COG1501	Belongs to the glycosyl hydrolase 31 family
BXO512_018855	COG1070	Carbohydrate kinase
BXO512_018865	COG0477	Major facilitator Superfamily
BXO512_018885	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BXO512_018935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BXO512_018940	COG2258	MOSC domain
BXO512_018950	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BXO512_018955	COG0505	Belongs to the CarA family
BXO512_018965	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BXO512_018970	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BXO512_018980	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BXO512_019045	COG2205	protein histidine kinase activity
BXO512_019045	COG0784	Response regulator, receiver
BXO512_019045	COG2198	Histidine kinase
BXO512_019050	COG1024	Enoyl-CoA hydratase
BXO512_019055	COG0318	PFAM AMP-dependent synthetase and ligase
BXO512_019085	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BXO512_019115	COG0840	transmembrane signaling receptor activity
BXO512_019150	COG0835	chemotaxis
BXO512_019165	COG0840	transmembrane signaling receptor activity
BXO512_019170	COG0840	transmembrane signaling receptor activity
BXO512_019175	COG0840	transmembrane signaling receptor activity
BXO512_019180	COG0840	transmembrane signaling receptor activity
BXO512_019190	COG0840	transmembrane signaling receptor activity
BXO512_019200	COG0840	transmembrane signaling receptor activity
BXO512_019230	COG0745	RESPONSE REGULATOR receiver
BXO512_019240	COG0835	chemotaxis
BXO512_019250	COG1360	Flagellar Motor Protein
BXO512_019255	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BXO512_019275	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BXO512_019285	COG4771	TonB-dependent receptor
BXO512_019320	COG3039	Transposase
BXO512_019470	COG3039	Transposase
BXO512_019480	COG3039	Transposase
BXO512_019495	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BXO512_019495	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BXO512_019500	COG1105	Belongs to the carbohydrate kinase PfkB family
BXO512_019505	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BXO512_019505	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BXO512_019510	COG1609	Transcriptional regulator
BXO512_019535	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BXO512_019540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BXO512_019550	COG2902	Dehydrogenase
BXO512_019555	COG3039	Transposase
BXO512_019565	COG0784	Response regulator, receiver
BXO512_019565	COG5002	protein histidine kinase activity
BXO512_019565	COG2205	protein histidine kinase activity
BXO512_019570	COG2733	membrane
BXO512_019580	COG1121	(ABC) transporter
BXO512_019585	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BXO512_019590	COG2223	nitrite transmembrane transporter activity
BXO512_019600	COG0243	molybdopterin cofactor binding
BXO512_019610	COG0477	Major facilitator Superfamily
BXO512_019620	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BXO512_019625	COG0174	glutamine synthetase
BXO512_019660	COG3842	ATPase activity
BXO512_019670	COG1177	transmembrane transport
BXO512_019680	COG1012	belongs to the aldehyde dehydrogenase family
BXO512_019695	COG4535	Mg2 and Co2 transporter CorC
BXO512_019715	COG1702	phosphate starvation-inducible protein PhoH
BXO512_019740	COG0741	lytic transglycosylase activity
BXO512_019745	COG0723	plastoquinol--plastocyanin reductase activity
BXO512_019750	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BXO512_019755	COG2857	Cytochrome c1
BXO512_019760	COG0625	glutathione transferase activity
BXO512_019765	COG2969	positive regulation of protein catabolic process
BXO512_019800	COG3328	transposase activity
BXO512_019875	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BXO512_019895	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BXO512_019900	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BXO512_019900	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BXO512_019905	COG0802	atpase or kinase
BXO512_019910	COG0860	N-Acetylmuramoyl-L-alanine amidase
BXO512_019915	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BXO512_019935	COG1028	Short-chain dehydrogenase reductase Sdr
BXO512_019945	COG0501	Belongs to the peptidase M48B family
BXO512_019955	COG2081	HI0933 family
BXO512_019960	COG4681	YaeQ
BXO512_019965	COG1671	Belongs to the UPF0178 family
BXO512_019975	COG0625	glutathione transferase activity
BXO512_019985	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BXO512_019990	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BXO512_019995	COG0513	Belongs to the DEAD box helicase family
BXO512_020000	COG0488	(ABC) transporter
BXO512_020020	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BXO512_020025	COG0483	inositol monophosphate 1-phosphatase activity
BXO512_020040	COG3300	MHYT domain
BXO512_020040	COG5001	Diguanylate cyclase
BXO512_020045	COG1509	lysine 2,3-aminomutase activity
BXO512_020060	COG0402	S-adenosylhomocysteine deaminase activity
BXO512_020065	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BXO512_020090	COG4677	pectinesterase activity
BXO512_020115	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BXO512_020140	COG2166	iron-sulfur cluster assembly
BXO512_020155	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BXO512_020160	COG0137	argininosuccinate synthase activity
BXO512_020170	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BXO512_020175	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BXO512_020190	COG0165	Argininosuccinate lyase
BXO512_020210	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BXO512_020245	COG3039	Transposase
BXO512_020260	COG4988	ABC transporter
BXO512_020265	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BXO512_020275	COG3039	Transposase
BXO512_020385	COG3209	COG3209 Rhs family protein
BXO512_020395	COG3039	Transposase
BXO512_020430	COG0643	Histidine kinase
BXO512_020430	COG2198	Histidine kinase
BXO512_020430	COG0784	Response regulator, receiver
BXO512_020485	COG1684	flagellar biosynthetic protein fliR
BXO512_020500	COG3190	flagellar
BXO512_020550	COG1677	Flagellar hook-basal body complex protein FliE
BXO512_020580	COG1028	Short-chain dehydrogenase reductase Sdr
BXO512_020590	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BXO512_020610	COG2201	protein-glutamate methylesterase activity
BXO512_020640	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BXO512_020645	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BXO512_020680	COG4787	bacterial-type flagellum-dependent cell motility
BXO512_020690	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BXO512_020695	COG1558	bacterial-type flagellum-dependent cell motility
BXO512_020705	COG0784	Response regulator, receiver
BXO512_020705	COG0835	chemotaxis
BXO512_020725	COG5002	protein histidine kinase activity
BXO512_020735	COG4585	Histidine kinase
BXO512_020740	COG5001	Diguanylate cyclase
BXO512_020765	COG0482	sulfurtransferase activity
BXO512_020780	COG0542	response to heat
BXO512_020805	COG0492	ferredoxin-NADP+ reductase activity
BXO512_020810	COG1674	ftsk spoiiie
BXO512_020830	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BXO512_020850	COG0038	chloride channel
BXO512_020855	COG0183	Belongs to the thiolase family
BXO512_020860	COG1250	3-hydroxyacyl-CoA dehydrogenase
BXO512_020860	COG1024	Enoyl-CoA hydratase
BXO512_020875	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BXO512_020885	COG1426	Protein conserved in bacteria
BXO512_020895	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BXO512_020905	COG0303	'Molybdopterin
BXO512_020960	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BXO512_021010	COG0742	ribosomal rna small subunit methyltransferase
BXO512_021015	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BXO512_021030	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BXO512_021035	COG0405	Gamma-glutamyltransferase
BXO512_021130	COG0343	queuine tRNA-ribosyltransferase activity
BXO512_021135	COG1862	Preprotein translocase
BXO512_021140	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BXO512_021145	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BXO512_021185	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BXO512_021195	COG0704	Plays a role in the regulation of phosphate uptake
BXO512_021210	COG0573	inorganic phosphate transmembrane transporter activity
BXO512_021215	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BXO512_021260	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BXO512_021270	COG1024	Enoyl-CoA hydratase
BXO512_021285	COG0494	nUDIX hydrolase
BXO512_021330	COG0116	Belongs to the methyltransferase superfamily
BXO512_021330	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BXO512_021355	COG0667	Aldo Keto reductase
BXO512_021365	COG2925	Exonuclease
BXO512_021400	COG0288	reversible hydration of carbon dioxide
BXO512_021430	COG0316	Belongs to the HesB IscA family
BXO512_021435	COG0360	Binds together with S18 to 16S ribosomal RNA
BXO512_021445	COG0359	binds to the 23S rRNA
BXO512_021455	COG3115	cell septum assembly
BXO512_021470	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
BXO512_021490	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BXO512_021515	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BXO512_021525	COG2986	histidine ammonia-lyase
BXO512_021530	COG1228	amidohydrolase
BXO512_021570	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BXO512_021580	COG1605	Chorismate mutase
BXO512_021580	COG0077	Prephenate dehydratase
BXO512_021585	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BXO512_021615	COG4566	intracellular signal transduction
BXO512_021660	COG0860	N-Acetylmuramoyl-L-alanine amidase
BXO512_021665	COG1469	GTP cyclohydrolase I activity
BXO512_021675	COG0617	tRNA 3'-terminal CCA addition
BXO512_021685	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BXO512_021690	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BXO512_021720	COG1472	Belongs to the glycosyl hydrolase 3 family
BXO512_021735	COG4251	negative regulation of phosphorylation
BXO512_021735	COG3706	GGDEF domain
BXO512_021735	COG5001	Diguanylate cyclase
BXO512_021735	COG2203	Gaf domain
BXO512_021795	COG1595	DNA-templated transcription, initiation
BXO512_021820	COG0386	Belongs to the glutathione peroxidase family
BXO512_021900	COG3039	Transposase
BXO512_021915	COG5002	protein histidine kinase activity
BXO512_021915	COG0784	Response regulator, receiver
BXO512_021915	COG2205	protein histidine kinase activity
BXO512_021955	COG0800	Aldolase
BXO512_021960	COG0129	dihydroxy-acid dehydratase activity
BXO512_021965	COG0363	glucosamine-6-phosphate deaminase activity
BXO512_021975	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BXO512_021990	COG0354	folic acid binding
BXO512_022005	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BXO512_022020	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BXO512_022035	COG4591	ABC-type transport system involved in lipoprotein release permease component
BXO512_022060	COG0811	peptide transport
BXO512_022075	COG1663	tetraacyldisaccharide 4'-kinase activity
BXO512_022085	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BXO512_022095	COG0322	excinuclease ABC activity
BXO512_022130	COG3328	transposase activity
BXO512_022150	COG3039	Transposase
BXO512_022165	COG2801	Transposase and inactivated derivatives
BXO512_022175	COG2201	protein-glutamate methylesterase activity
BXO512_022225	COG0653	protein targeting
BXO512_022315	COG0140	phosphoribosyl-ATP diphosphatase activity
BXO512_022315	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BXO512_022325	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BXO512_022335	COG0131	Imidazoleglycerol-phosphate dehydratase
BXO512_022335	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BXO512_022350	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BXO512_022370	COG0124	histidyl-tRNA synthetase
BXO512_022385	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BXO512_022420	COG1012	belongs to the aldehyde dehydrogenase family
BXO512_022435	COG0167	dihydroorotate dehydrogenase activity
BXO512_022440	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BXO512_022445	COG0697	spore germination
BXO512_022450	COG1794	racemase activity, acting on amino acids and derivatives
BXO512_022470	COG0671	phosphoesterase, PA-phosphatase related
BXO512_022485	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BXO512_022500	COG2183	response to ionizing radiation
BXO512_022510	COG0723	plastoquinol--plastocyanin reductase activity
BXO512_022510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BXO512_022525	COG3243	poly(R)-hydroxyalkanoic acid synthase
BXO512_022535	COG1183	phosphatidylcholine synthase activity
BXO512_022540	COG1028	Short-chain dehydrogenase reductase Sdr
BXO512_022565	COG0668	transmembrane transport
BXO512_022585	COG1914	H( )-stimulated, divalent metal cation uptake system
BXO512_022635	COG0583	DNA-binding transcription factor activity
BXO512_022640	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BXO512_022645	COG3002	Belongs to the UPF0753 family
BXO512_022660	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BXO512_022680	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BXO512_022690	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BXO512_022695	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BXO512_022705	COG0776	regulation of translation
BXO512_022710	COG0539	negative regulation of cytoplasmic translation
BXO512_022715	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BXO512_022730	COG2957	Belongs to the agmatine deiminase family
BXO512_022740	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BXO512_022765	COG0395	ABC-type sugar transport system, permease component
BXO512_022770	COG1175	transmembrane transport
BXO512_022800	COG2350	Protein conserved in bacteria
BXO512_022805	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BXO512_022810	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BXO512_022815	COG1187	pseudouridine synthase activity
BXO512_022840	COG0436	Aminotransferase
BXO512_022905	COG0277	FAD linked oxidase domain protein
BXO512_022910	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BXO512_022920	COG0531	amino acid
BXO512_022925	COG0531	amino acid
BXO512_022930	COG0235	Class ii aldolase
BXO512_022935	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BXO512_022965	COG2201	protein-glutamate methylesterase activity