locus-tag	class	description
H9N23_00015	COG4783	chaperone-mediated protein folding
H9N23_00080	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H9N23_00085	COG0583	DNA-binding transcription factor activity
H9N23_00090	COG3634	alkyl hydroperoxide reductase activity
H9N23_00100	COG2890	protein-(glutamine-N5) methyltransferase activity
H9N23_00150	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H9N23_00150	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H9N23_00165	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
H9N23_00190	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
H9N23_00215	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H9N23_00225	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H9N23_00255	COG1295	ribonuclease BN
H9N23_00260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H9N23_00280	COG0521	Mo-molybdopterin cofactor biosynthetic process
H9N23_00290	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
H9N23_00305	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
H9N23_00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H9N23_00330	COG0193	aminoacyl-tRNA hydrolase activity
H9N23_00335	COG0012	GTP binding
H9N23_00365	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H9N23_00370	COG0250	Participates in transcription elongation, termination and antitermination
H9N23_00375	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
H9N23_00385	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
H9N23_00390	COG0222	ribosome binding
H9N23_00395	COG0085	RNA polymerase activity
H9N23_00400	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
H9N23_00405	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
H9N23_00410	COG0049	tRNA binding
H9N23_00430	COG0051	transcription antitermination factor activity, RNA binding
H9N23_00435	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
H9N23_00440	COG0088	Forms part of the polypeptide exit tunnel
H9N23_00445	COG0089	rRNA binding
H9N23_00460	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
H9N23_00470	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
H9N23_00475	COG0255	Belongs to the universal ribosomal protein uL29 family
H9N23_00480	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
H9N23_00485	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
H9N23_00495	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
H9N23_00525	COG1841	ribosomal large subunit assembly
H9N23_00535	COG0201	protein transport
H9N23_00545	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
H9N23_00550	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
H9N23_00560	COG0203	ribosomal protein L17
H9N23_00620	COG3551	Protein conserved in bacteria
H9N23_00650	COG2194	sulfuric ester hydrolase activity
H9N23_00660	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
H9N23_00665	COG0745	RESPONSE REGULATOR receiver
H9N23_00670	COG0642	Histidine kinase
H9N23_00680	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
H9N23_00685	COG2894	cell division
H9N23_00700	COG4585	Histidine kinase
H9N23_00705	COG2197	response regulator
H9N23_00730	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
H9N23_00820	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H9N23_00830	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H9N23_00895	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H9N23_00950	COG3179	chitinase
H9N23_01135	COG0732	type I restriction modification DNA specificity domain
H9N23_01150	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
H9N23_01170	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
H9N23_01175	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
H9N23_01180	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
H9N23_01195	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
H9N23_01230	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H9N23_01235	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H9N23_01290	COG1297	OPT oligopeptide transporter protein
H9N23_01295	COG3039	Transposase
H9N23_01315	COG1506	peptidase
H9N23_01315	COG0823	Involved in the tonB-independent uptake of proteins
H9N23_01335	COG2207	Transcriptional regulator
H9N23_01335	COG1917	Cupin 2, conserved barrel domain protein
H9N23_01360	COG3039	Transposase
H9N23_01380	COG0753	catalase activity
H9N23_01420	COG0469	pyruvate kinase activity
H9N23_01425	COG3588	fructose-bisphosphate aldolase
H9N23_01430	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
H9N23_01480	COG2198	Histidine kinase
H9N23_01480	COG0784	Response regulator, receiver
H9N23_01480	COG2205	protein histidine kinase activity
H9N23_01500	COG0175	sulfate reduction
H9N23_01505	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H9N23_01510	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H9N23_01515	COG0175	sulfate reduction
H9N23_01520	COG0529	Catalyzes the synthesis of activated sulfate
H9N23_01520	COG2895	sulfate adenylyltransferase (ATP) activity
H9N23_01530	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H9N23_01535	COG0308	aminopeptidase N
H9N23_01555	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H9N23_01580	COG1970	mechanosensitive ion channel activity
H9N23_01595	COG3039	Transposase
H9N23_01615	COG0471	metal ion transport
H9N23_01615	COG3273	potassium ion transport
H9N23_01625	COG2022	thiamine diphosphate biosynthetic process
H9N23_01705	COG3039	Transposase
H9N23_01710	COG3039	Transposase
H9N23_01775	COG3118	belongs to the thioredoxin family
H9N23_01800	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
H9N23_01825	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
H9N23_01850	COG2968	Membrane
H9N23_01865	COG3164	Protein of unknown function
H9N23_01875	COG0312	modulator of DNA gyrase
H9N23_01880	COG3028	Belongs to the UPF0307 family
H9N23_01885	COG0312	modulator of DNA gyrase
H9N23_01910	COG0142	geranyltranstransferase activity
H9N23_01915	COG1722	exodeoxyribonuclease VII activity
H9N23_01920	COG0037	tRNA processing
H9N23_01925	COG1785	Belongs to the alkaline phosphatase family
H9N23_01930	COG1301	dicarboxylic acid transport
H9N23_01945	COG0791	NLP P60 protein
H9N23_01950	COG0791	NLP P60 protein
H9N23_01955	COG1047	Peptidyl-prolyl cis-trans
H9N23_01960	COG2311	Membrane
H9N23_01965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H9N23_02005	COG0489	protein tyrosine kinase activity
H9N23_02010	COG0717	Belongs to the dCTP deaminase family
H9N23_02030	COG0412	Dienelactone hydrolase
H9N23_02040	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H9N23_02080	COG2890	protein-(glutamine-N5) methyltransferase activity
H9N23_02085	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
H9N23_02090	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H9N23_02095	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H9N23_02115	COG0101	tRNA pseudouridine synthase activity
H9N23_02120	COG0135	phosphoribosylanthranilate isomerase activity
H9N23_02145	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
H9N23_02150	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H9N23_02195	COG0149	triose-phosphate isomerase activity
H9N23_02210	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H9N23_02220	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H9N23_02225	COG0649	NAD binding
H9N23_02230	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
H9N23_02235	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
H9N23_02240	COG1034	ATP synthesis coupled electron transport
H9N23_02245	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
H9N23_02275	COG1007	ATP synthesis coupled electron transport
H9N23_02285	COG0779	Required for maturation of 30S ribosomal subunits
H9N23_02290	COG0195	Participates in both transcription termination and antitermination
H9N23_02310	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
H9N23_02315	COG1185	polyribonucleotide nucleotidyltransferase activity
H9N23_02350	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
H9N23_02360	COG2095	MarC family integral membrane protein
H9N23_02375	COG1611	Belongs to the LOG family
H9N23_02415	COG4969	Belongs to the N-Me-Phe pilin family
H9N23_02420	COG0556	nucleotide-excision repair
H9N23_02455	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
H9N23_02525	COG0438	transferase activity, transferring glycosyl groups
H9N23_02530	COG0438	transferase activity, transferring glycosyl groups
H9N23_02540	COG0438	transferase activity, transferring glycosyl groups
H9N23_02580	COG3040	lipid binding
H9N23_02665	COG3039	Transposase
H9N23_02670	COG0784	Response regulator, receiver
H9N23_02670	COG4191	Histidine kinase
H9N23_02690	COG0552	protein localization to endoplasmic reticulum
H9N23_02700	COG3938	Belongs to the proline racemase family
H9N23_02705	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H9N23_02720	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H9N23_02730	COG0006	proline dipeptidase activity
H9N23_02745	COG0531	amino acid
H9N23_02795	COG4206	TonB-dependent receptor
H9N23_02820	COG4206	TonB-dependent receptor
H9N23_02890	COG0746	molybdenum cofactor guanylyltransferase activity
H9N23_02915	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H9N23_02915	COG1648	precorrin-2 dehydrogenase activity
H9N23_02955	COG3039	Transposase
H9N23_02965	COG3039	Transposase
H9N23_03000	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
H9N23_03020	COG3039	Transposase
H9N23_03025	COG1054	Belongs to the UPF0176 family
H9N23_03040	COG1530	ribonuclease E activity
H9N23_03050	COG3064	Membrane
H9N23_03055	COG0428	transporter
H9N23_03060	COG0428	transporter
H9N23_03070	COG2154	pterin-4-alpha-carbinolamine dehydratase
H9N23_03075	COG0316	Belongs to the HesB IscA family
H9N23_03075	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
H9N23_03125	COG3039	Transposase
H9N23_03235	COG0631	protein serine/threonine phosphatase activity
H9N23_03240	COG0515	serine threonine protein kinase
H9N23_03275	COG1858	cytochrome C peroxidase
H9N23_03325	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H9N23_03330	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H9N23_03350	COG2201	protein-glutamate methylesterase activity
H9N23_03395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H9N23_03415	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H9N23_03430	COG1595	DNA-templated transcription, initiation
H9N23_03480	COG2244	polysaccharide biosynthetic process
H9N23_03510	COG2264	protein methyltransferase activity
H9N23_03520	COG0438	transferase activity, transferring glycosyl groups
H9N23_03540	COG1136	(ABC) transporter
H9N23_03545	COG1132	(ABC) transporter
H9N23_03555	COG0477	Major facilitator Superfamily
H9N23_03565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H9N23_03580	COG1253	flavin adenine dinucleotide binding
H9N23_03590	COG0306	phosphate transporter
H9N23_03595	COG1434	Gram-negative-bacterium-type cell wall biogenesis
H9N23_03620	COG0504	CTP synthase activity
H9N23_03625	COG2877	3-deoxy-8-phosphooctulonate synthase activity
H9N23_03635	COG0148	phosphopyruvate hydratase activity
H9N23_03640	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
H9N23_03655	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
H9N23_03665	COG2840	Smr protein MutS2
H9N23_03670	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
H9N23_03675	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
H9N23_03680	COG1238	metal cluster binding
H9N23_03695	COG1534	Rna-binding protein
H9N23_03700	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
H9N23_03710	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H9N23_03725	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H9N23_03730	COG1546	Belongs to the CinA family
H9N23_03745	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
H9N23_03750	COG2137	regulation of response to DNA damage stimulus
H9N23_03755	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
H9N23_03760	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
H9N23_03780	COG0305	Participates in initiation and elongation during chromosome replication
H9N23_03785	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
H9N23_03805	COG1741	Belongs to the pirin family
H9N23_03810	COG0583	DNA-binding transcription factor activity
H9N23_03840	COG0351	phosphomethylpyrimidine kinase
H9N23_03850	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
H9N23_03855	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H9N23_03870	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H9N23_03880	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
H9N23_03885	COG3734	2-keto-3-deoxy-galactonokinase
H9N23_03895	COG4948	Mandelate Racemase Muconate Lactonizing
H9N23_03900	COG0800	Aldolase
H9N23_03915	COG1501	Belongs to the glycosyl hydrolase 31 family
H9N23_03925	COG1070	Carbohydrate kinase
H9N23_03935	COG0477	Major facilitator Superfamily
H9N23_03955	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
H9N23_04005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H9N23_04010	COG2258	MOSC domain
H9N23_04020	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
H9N23_04025	COG0505	Belongs to the CarA family
H9N23_04035	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
H9N23_04040	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H9N23_04050	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H9N23_04060	COG3039	Transposase
H9N23_04075	COG3039	Transposase
H9N23_04120	COG2198	Histidine kinase
H9N23_04120	COG0784	Response regulator, receiver
H9N23_04120	COG2205	protein histidine kinase activity
H9N23_04125	COG1024	Enoyl-CoA hydratase
H9N23_04130	COG0318	PFAM AMP-dependent synthetase and ligase
H9N23_04160	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H9N23_04190	COG0840	transmembrane signaling receptor activity
H9N23_04210	COG0835	chemotaxis
H9N23_04225	COG0840	transmembrane signaling receptor activity
H9N23_04230	COG0840	transmembrane signaling receptor activity
H9N23_04235	COG0840	transmembrane signaling receptor activity
H9N23_04240	COG0840	transmembrane signaling receptor activity
H9N23_04250	COG0840	transmembrane signaling receptor activity
H9N23_04260	COG0840	transmembrane signaling receptor activity
H9N23_04270	COG0840	transmembrane signaling receptor activity
H9N23_04290	COG0745	RESPONSE REGULATOR receiver
H9N23_04300	COG0835	chemotaxis
H9N23_04310	COG1360	Flagellar Motor Protein
H9N23_04315	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
H9N23_04335	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H9N23_04345	COG4771	TonB-dependent receptor
H9N23_04375	COG3039	Transposase
H9N23_04520	COG3039	Transposase
H9N23_04535	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H9N23_04535	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H9N23_04540	COG1105	Belongs to the carbohydrate kinase PfkB family
H9N23_04545	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H9N23_04545	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9N23_04550	COG1609	Transcriptional regulator
H9N23_04570	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H9N23_04575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H9N23_04585	COG2902	Dehydrogenase
H9N23_04590	COG3039	Transposase
H9N23_04600	COG0784	Response regulator, receiver
H9N23_04600	COG2205	protein histidine kinase activity
H9N23_04600	COG5002	protein histidine kinase activity
H9N23_04605	COG2733	membrane
H9N23_04615	COG1121	(ABC) transporter
H9N23_04620	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H9N23_04625	COG2223	nitrite transmembrane transporter activity
H9N23_04635	COG0243	molybdopterin cofactor binding
H9N23_04645	COG0477	Major facilitator Superfamily
H9N23_04655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H9N23_04660	COG0174	glutamine synthetase
H9N23_04695	COG3842	ATPase activity
H9N23_04705	COG1177	transmembrane transport
H9N23_04715	COG1012	belongs to the aldehyde dehydrogenase family
H9N23_04730	COG4535	Mg2 and Co2 transporter CorC
H9N23_04750	COG1702	phosphate starvation-inducible protein PhoH
H9N23_04780	COG0741	lytic transglycosylase activity
H9N23_04785	COG0723	plastoquinol--plastocyanin reductase activity
H9N23_04790	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
H9N23_04795	COG2857	Cytochrome c1
H9N23_04800	COG0625	glutathione transferase activity
H9N23_04805	COG2969	positive regulation of protein catabolic process
H9N23_04840	COG3328	transposase activity
H9N23_04915	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H9N23_04940	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H9N23_04945	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H9N23_04945	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
H9N23_04950	COG0802	atpase or kinase
H9N23_04955	COG0860	N-Acetylmuramoyl-L-alanine amidase
H9N23_04960	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
H9N23_04980	COG1028	Short-chain dehydrogenase reductase Sdr
H9N23_05000	COG2081	HI0933 family
H9N23_05005	COG4681	YaeQ
H9N23_05010	COG1671	Belongs to the UPF0178 family
H9N23_05020	COG0625	glutathione transferase activity
H9N23_05040	COG0513	Belongs to the DEAD box helicase family
H9N23_05045	COG0488	(ABC) transporter
H9N23_05065	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H9N23_05070	COG0483	inositol monophosphate 1-phosphatase activity
H9N23_05085	COG3300	MHYT domain
H9N23_05085	COG5001	Diguanylate cyclase
H9N23_05090	COG1509	lysine 2,3-aminomutase activity
H9N23_05105	COG0402	S-adenosylhomocysteine deaminase activity
H9N23_05110	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H9N23_05135	COG4677	pectinesterase activity
H9N23_05145	COG3039	Transposase
H9N23_05180	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
H9N23_05205	COG2166	iron-sulfur cluster assembly
H9N23_05220	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
H9N23_05225	COG0137	argininosuccinate synthase activity
H9N23_05235	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H9N23_05240	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
H9N23_05255	COG0165	Argininosuccinate lyase
H9N23_05275	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
H9N23_05310	COG3039	Transposase
H9N23_05325	COG4988	ABC transporter
H9N23_05330	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
H9N23_05340	COG3039	Transposase
H9N23_05425	COG3039	Transposase
H9N23_05435	COG3039	Transposase
H9N23_05445	COG3039	Transposase
H9N23_05455	COG3209	COG3209 Rhs family protein
H9N23_05465	COG3039	Transposase
H9N23_05495	COG0784	Response regulator, receiver
H9N23_05495	COG2198	Histidine kinase
H9N23_05495	COG0643	Histidine kinase
H9N23_05550	COG1684	flagellar biosynthetic protein fliR
H9N23_05565	COG3190	flagellar
H9N23_05615	COG1677	Flagellar hook-basal body complex protein FliE
H9N23_05645	COG1028	Short-chain dehydrogenase reductase Sdr
H9N23_05655	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H9N23_05675	COG2201	protein-glutamate methylesterase activity
H9N23_05705	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
H9N23_05710	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H9N23_05745	COG4787	bacterial-type flagellum-dependent cell motility
H9N23_05755	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
H9N23_05760	COG1558	bacterial-type flagellum-dependent cell motility
H9N23_05770	COG0784	Response regulator, receiver
H9N23_05770	COG0835	chemotaxis
H9N23_05790	COG5002	protein histidine kinase activity
H9N23_05800	COG4585	Histidine kinase
H9N23_05805	COG5001	Diguanylate cyclase
H9N23_05830	COG0482	sulfurtransferase activity
H9N23_05845	COG0542	response to heat
H9N23_05870	COG0492	ferredoxin-NADP+ reductase activity
H9N23_05875	COG1674	ftsk spoiiie
H9N23_05895	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H9N23_05915	COG0038	chloride channel
H9N23_05920	COG0183	Belongs to the thiolase family
H9N23_05925	COG1024	Enoyl-CoA hydratase
H9N23_05925	COG1250	3-hydroxyacyl-CoA dehydrogenase
H9N23_05940	COG0820	rRNA (adenine-C2-)-methyltransferase activity
H9N23_05950	COG1426	Protein conserved in bacteria
H9N23_05960	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H9N23_05970	COG0303	'Molybdopterin
H9N23_06000	COG3039	Transposase
H9N23_06035	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H9N23_06055	COG0742	ribosomal rna small subunit methyltransferase
H9N23_06060	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
H9N23_06070	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H9N23_06075	COG0405	Gamma-glutamyltransferase
H9N23_06150	COG0343	queuine tRNA-ribosyltransferase activity
H9N23_06155	COG1862	Preprotein translocase
H9N23_06160	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H9N23_06165	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H9N23_06195	COG3328	transposase activity
H9N23_06210	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H9N23_06220	COG0704	Plays a role in the regulation of phosphate uptake
H9N23_06235	COG0573	inorganic phosphate transmembrane transporter activity
H9N23_06240	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H9N23_06280	COG3039	Transposase
H9N23_06295	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H9N23_06305	COG1024	Enoyl-CoA hydratase
H9N23_06315	COG0494	nUDIX hydrolase
H9N23_06360	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
H9N23_06360	COG0116	Belongs to the methyltransferase superfamily
H9N23_06385	COG0667	Aldo Keto reductase
H9N23_06395	COG2925	Exonuclease
H9N23_06420	COG0288	reversible hydration of carbon dioxide
H9N23_06450	COG0316	Belongs to the HesB IscA family
H9N23_06455	COG0360	Binds together with S18 to 16S ribosomal RNA
H9N23_06465	COG0359	binds to the 23S rRNA
H9N23_06475	COG3115	cell septum assembly
H9N23_06495	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
H9N23_06510	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
H9N23_06535	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
H9N23_06545	COG2986	histidine ammonia-lyase
H9N23_06550	COG1228	amidohydrolase
H9N23_06590	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
H9N23_06600	COG1605	Chorismate mutase
H9N23_06600	COG0077	Prephenate dehydratase
H9N23_06605	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
H9N23_06635	COG4566	intracellular signal transduction
H9N23_06680	COG0860	N-Acetylmuramoyl-L-alanine amidase
H9N23_06685	COG1469	GTP cyclohydrolase I activity
H9N23_06695	COG0617	tRNA 3'-terminal CCA addition
H9N23_06710	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
H9N23_06740	COG1472	Belongs to the glycosyl hydrolase 3 family
H9N23_06755	COG5001	Diguanylate cyclase
H9N23_06755	COG2203	Gaf domain
H9N23_06755	COG3706	GGDEF domain
H9N23_06755	COG4251	negative regulation of phosphorylation
H9N23_06840	COG0386	Belongs to the glutathione peroxidase family
H9N23_06920	COG0784	Response regulator, receiver
H9N23_06920	COG2205	protein histidine kinase activity
H9N23_06920	COG5002	protein histidine kinase activity
H9N23_06950	COG0800	Aldolase
H9N23_06955	COG0129	dihydroxy-acid dehydratase activity
H9N23_06960	COG0363	glucosamine-6-phosphate deaminase activity
H9N23_06970	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
H9N23_06985	COG0354	folic acid binding
H9N23_07000	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
H9N23_07015	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H9N23_07030	COG4591	ABC-type transport system involved in lipoprotein release permease component
H9N23_07055	COG0811	peptide transport
H9N23_07070	COG1663	tetraacyldisaccharide 4'-kinase activity
H9N23_07080	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H9N23_07090	COG0322	excinuclease ABC activity
H9N23_07125	COG3328	transposase activity
H9N23_07145	COG3039	Transposase
H9N23_07165	COG2801	Transposase and inactivated derivatives
H9N23_07175	COG2201	protein-glutamate methylesterase activity
H9N23_07380	COG0653	protein targeting
H9N23_07420	COG0140	phosphoribosyl-ATP diphosphatase activity
H9N23_07420	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
H9N23_07430	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
H9N23_07440	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
H9N23_07440	COG0131	Imidazoleglycerol-phosphate dehydratase
H9N23_07455	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
H9N23_07475	COG0124	histidyl-tRNA synthetase
H9N23_07490	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H9N23_07525	COG1012	belongs to the aldehyde dehydrogenase family
H9N23_07550	COG0697	spore germination
H9N23_07555	COG1794	racemase activity, acting on amino acids and derivatives
H9N23_07575	COG0671	phosphoesterase, PA-phosphatase related
H9N23_07590	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
H9N23_07605	COG2183	response to ionizing radiation
H9N23_07615	COG0723	plastoquinol--plastocyanin reductase activity
H9N23_07615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H9N23_07630	COG3243	poly(R)-hydroxyalkanoic acid synthase
H9N23_07640	COG1183	phosphatidylcholine synthase activity
H9N23_07645	COG1028	Short-chain dehydrogenase reductase Sdr
H9N23_07695	COG0668	transmembrane transport
H9N23_07715	COG1914	H( )-stimulated, divalent metal cation uptake system
H9N23_07735	COG0583	DNA-binding transcription factor activity
H9N23_07765	COG0583	DNA-binding transcription factor activity
H9N23_07770	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H9N23_07775	COG3002	Belongs to the UPF0753 family
H9N23_07790	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
H9N23_07810	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H9N23_07820	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H9N23_07825	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
H9N23_07835	COG0776	regulation of translation
H9N23_07840	COG0539	negative regulation of cytoplasmic translation
H9N23_07845	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
H9N23_07860	COG2957	Belongs to the agmatine deiminase family
H9N23_07870	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H9N23_07895	COG0395	ABC-type sugar transport system, permease component
H9N23_07900	COG1175	transmembrane transport
H9N23_07930	COG2350	Protein conserved in bacteria
H9N23_07935	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
H9N23_07940	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
H9N23_07945	COG1187	pseudouridine synthase activity
H9N23_07970	COG0436	Aminotransferase
H9N23_08035	COG0277	FAD linked oxidase domain protein
H9N23_08040	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H9N23_08050	COG0531	amino acid
H9N23_08055	COG0531	amino acid
H9N23_08065	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
H9N23_08095	COG2201	protein-glutamate methylesterase activity
H9N23_08140	COG0583	DNA-binding transcription factor activity
H9N23_08150	COG3039	Transposase
H9N23_08200	COG3039	Transposase
H9N23_08250	COG3039	Transposase
H9N23_08265	COG1278	Cold shock
H9N23_08275	COG3328	transposase activity
H9N23_08295	COG3039	Transposase
H9N23_08305	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H9N23_08325	COG0557	exoribonuclease II activity
H9N23_08350	COG1960	acyl-CoA dehydrogenase activity
H9N23_08355	COG2226	methyltransferase
H9N23_08360	COG1410	methionine synthase
H9N23_08360	COG0646	methionine synthase
H9N23_08365	COG1410	methionine synthase
H9N23_08365	COG0646	methionine synthase
H9N23_08375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H9N23_08385	COG1609	Transcriptional regulator
H9N23_08400	COG2900	Belongs to the SlyX family
H9N23_08415	COG0386	Belongs to the glutathione peroxidase family
H9N23_08425	COG1725	Transcriptional regulator
H9N23_08430	COG1131	(ABC) transporter
H9N23_08505	COG2850	peptidyl-arginine hydroxylation
H9N23_08540	COG1132	(ABC) transporter
H9N23_08555	COG0583	DNA-binding transcription factor activity
H9N23_08570	COG0287	Prephenate dehydrogenase
H9N23_08570	COG1605	Chorismate mutase
H9N23_08575	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
H9N23_08580	COG0484	heat shock protein binding
H9N23_08585	COG0443	Heat shock 70 kDa protein
H9N23_08590	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
H9N23_08600	COG0497	DNA recombination
H9N23_08610	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H9N23_08615	COG2914	Belongs to the UPF0125 (RnfH) family
H9N23_08640	COG1960	acyl-CoA dehydrogenase activity
H9N23_08650	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
H9N23_08695	COG2814	Major facilitator Superfamily
H9N23_08700	COG1566	PFAM secretion protein HlyD family protein
H9N23_08735	COG4774	siderophore transport
H9N23_08745	COG0367	asparagine synthase
H9N23_08760	COG1393	Belongs to the ArsC family
H9N23_08820	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
H9N23_08835	COG0233	cytoplasmic translational termination
H9N23_08845	COG0575	Belongs to the CDS family
H9N23_08855	COG0750	zinc metalloprotease
H9N23_08870	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H9N23_08875	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H9N23_08895	COG0825	malonyl-CoA metabolic process
H9N23_08905	COG4771	TonB-dependent receptor
H9N23_08910	COG1131	(ABC) transporter
H9N23_08930	COG1981	membrane
H9N23_08975	COG2895	sulfate adenylyltransferase (ATP) activity
H9N23_08975	COG0529	Catalyzes the synthesis of activated sulfate
H9N23_09010	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
H9N23_09025	COG2040	homocysteine
H9N23_09030	COG0833	amino acid
H9N23_09050	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H9N23_09050	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H9N23_09060	COG2878	Part of a membrane complex involved in electron transport
H9N23_09080	COG1595	DNA-templated transcription, initiation
H9N23_09105	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H9N23_09120	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H9N23_09125	COG0251	oxidation-reduction process
H9N23_09135	COG0392	lysyltransferase activity
H9N23_09135	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
H9N23_09180	COG2814	Major facilitator Superfamily
H9N23_09185	COG1902	pentaerythritol trinitrate reductase activity
H9N23_09195	COG2824	Alkylphosphonate utilization operon protein PhnA
H9N23_09210	COG1047	Peptidyl-prolyl cis-trans
H9N23_09245	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H9N23_09260	COG1451	nucleotide metabolic process
H9N23_09280	COG0183	Belongs to the thiolase family
H9N23_09310	COG1793	dna ligase
H9N23_09310	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
H9N23_09320	COG1793	dna ligase
H9N23_09325	COG1201	RNA secondary structure unwinding
H9N23_09345	COG1278	Cold shock
H9N23_09350	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
H9N23_09355	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
H9N23_09365	COG3046	protein related to deoxyribodipyrimidine photolyase
H9N23_09370	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
H9N23_09375	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
H9N23_09390	COG2954	triphosphatase activity
H9N23_09405	COG1381	Involved in DNA repair and RecF pathway recombination
H9N23_09435	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H9N23_09450	COG1024	Enoyl-CoA hydratase
H9N23_09450	COG1250	3-hydroxyacyl-CoA dehydrogenase
H9N23_09470	COG1024	Enoyl-CoA hydratase
H9N23_09475	COG1960	acyl-CoA dehydrogenase activity
H9N23_09495	COG3867	Arabinogalactan endo-beta-1,4-galactanase
H9N23_09545	COG2353	YceI-like domain
H9N23_09555	COG2353	YceI-like domain
H9N23_09570	COG1760	l-serine dehydratase
H9N23_09580	COG0626	cystathionine gamma-synthase activity
H9N23_09585	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H9N23_09590	COG0739	heme binding
H9N23_09600	COG1272	protein, Hemolysin III
H9N23_09620	COG0463	Glycosyl transferase, family 2
H9N23_09630	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
H9N23_09640	COG4771	TonB-dependent receptor
H9N23_09645	COG1309	transcriptional regulator
H9N23_09655	COG1960	acyl-CoA dehydrogenase activity
H9N23_09690	COG0509	glycine decarboxylation via glycine cleavage system
H9N23_09705	COG0330	HflC and HflK could
H9N23_09720	COG3956	TIGRFAM MazG family protein
H9N23_09730	COG0494	nUDIX hydrolase
H9N23_09740	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H9N23_09745	COG0837	glucose binding
H9N23_09760	COG1388	LysM domain
H9N23_09760	COG3858	chitin binding
H9N23_09770	COG3525	Glycosyl hydrolase, family 20, catalytic domain
H9N23_09780	COG1472	Belongs to the glycosyl hydrolase 3 family
H9N23_09850	COG3537	Alpha-1,2-mannosidase
H9N23_09900	COG3142	Participates in the control of copper homeostasis
H9N23_09905	COG1446	asparaginase
H9N23_09940	COG2198	Histidine kinase
H9N23_09940	COG0643	Histidine kinase
H9N23_09940	COG0784	Response regulator, receiver
H9N23_09945	COG0840	transmembrane signaling receptor activity
H9N23_09950	COG0835	chemotaxis
H9N23_09965	COG0189	ligase activity
H9N23_09975	COG1397	ADP-ribosylglycohydrolase
H9N23_09985	COG1199	ATP-dependent helicase activity
H9N23_09995	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H9N23_10000	COG1215	transferase activity, transferring glycosyl groups
H9N23_10010	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H9N23_10065	COG1643	Atp-dependent helicase
H9N23_10070	COG0783	Belongs to the Dps family
H9N23_10075	COG0514	ATP-dependent DNA helicase (RecQ)
H9N23_10095	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
H9N23_10145	COG1187	pseudouridine synthase activity
H9N23_10150	COG0602	queuosine metabolic process
H9N23_10160	COG2885	chlorophyll binding
H9N23_10175	COG0848	biopolymer transport protein
H9N23_10185	COG0824	Thioesterase
H9N23_10190	COG2255	four-way junction helicase activity
H9N23_10200	COG0632	four-way junction helicase activity
H9N23_10305	COG3209	COG3209 Rhs family protein
H9N23_10315	COG3209	COG3209 Rhs family protein
H9N23_10335	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H9N23_10340	COG1845	cytochrome c oxidase, subunit III
H9N23_10345	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H9N23_10360	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
H9N23_10365	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
H9N23_10375	COG0196	riboflavin kinase activity
H9N23_10380	COG0728	peptidoglycan biosynthetic process
H9N23_10385	COG0268	Binds directly to 16S ribosomal RNA
H9N23_10390	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
H9N23_10395	COG0211	Belongs to the bacterial ribosomal protein bL27 family
H9N23_10405	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H9N23_10410	COG0824	Thioesterase
H9N23_10425	COG1946	Acyl-CoA thioesterase
H9N23_10435	COG1595	DNA-templated transcription, initiation
H9N23_10455	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
H9N23_10495	COG1877	trehalose-phosphatase activity
H9N23_10500	COG3387	PFAM Glycoside hydrolase 15-related
H9N23_10525	COG0564	pseudouridine synthase activity
H9N23_10530	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H9N23_10535	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
H9N23_10535	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H9N23_10545	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H9N23_10550	COG0045	succinate-CoA ligase (ADP-forming) activity
H9N23_10590	COG2194	sulfuric ester hydrolase activity
H9N23_10595	COG4969	Belongs to the N-Me-Phe pilin family
H9N23_10605	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
H9N23_10640	COG3039	Transposase
H9N23_10665	COG3039	Transposase
H9N23_10690	COG3293	Transposase
H9N23_10695	COG1132	(ABC) transporter
H9N23_10725	COG0745	RESPONSE REGULATOR receiver
H9N23_10730	COG5002	protein histidine kinase activity
H9N23_10730	COG5000	phosphorelay sensor kinase activity
H9N23_10735	COG0475	glutathione-regulated potassium exporter activity
H9N23_10745	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H9N23_10765	COG1187	pseudouridine synthase activity
H9N23_10770	COG5001	Diguanylate cyclase
H9N23_10770	COG5002	protein histidine kinase activity
H9N23_10870	COG1028	Short-chain dehydrogenase reductase Sdr
H9N23_10885	COG0415	Belongs to the DNA photolyase family
H9N23_10890	COG0305	Participates in initiation and elongation during chromosome replication
H9N23_10900	COG0367	asparagine synthase
H9N23_10915	COG1960	acyl-CoA dehydrogenase activity
H9N23_10930	COG0084	hydrolase, TatD family'
H9N23_10935	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H9N23_10995	COG0735	belongs to the Fur family
H9N23_11000	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H9N23_11035	COG3039	Transposase
H9N23_11060	COG3039	Transposase
H9N23_11085	COG2205	protein histidine kinase activity
H9N23_11095	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
H9N23_11105	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H9N23_11120	COG2198	Histidine kinase
H9N23_11120	COG0643	Histidine kinase
H9N23_11125	COG0840	transmembrane signaling receptor activity
H9N23_11130	COG0835	chemotaxis
H9N23_11135	COG2199	diguanylate cyclase activity
H9N23_11135	COG2200	EAL domain
H9N23_11135	COG2202	Pas domain
H9N23_11140	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
H9N23_11155	COG3590	peptidase
H9N23_11175	COG1515	deoxyribonuclease V activity
H9N23_11185	COG1741	Belongs to the pirin family
H9N23_11275	COG1741	Belongs to the pirin family
H9N23_11280	COG1966	Carbon starvation protein
H9N23_11285	COG2879	small protein
H9N23_11320	COG5001	Diguanylate cyclase
H9N23_11320	COG3706	GGDEF domain
H9N23_11320	COG2203	Gaf domain
H9N23_11320	COG4251	negative regulation of phosphorylation
H9N23_11325	COG0629	single-stranded DNA binding
H9N23_11330	COG0142	geranyltranstransferase activity
H9N23_11355	COG0527	aspartate kinase activity
H9N23_11365	COG0384	phenazine biosynthesis protein PhzF
H9N23_11375	COG1764	response to oxidative stress
H9N23_11390	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
H9N23_11395	COG1678	Uncharacterized ACR, COG1678
H9N23_11405	COG0519	Catalyzes the synthesis of GMP from XMP
H9N23_11435	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
H9N23_11475	COG0693	protein deglycase activity
H9N23_11495	COG1959	2 iron, 2 sulfur cluster binding
H9N23_11500	COG0719	Fe-S assembly protein
H9N23_11505	COG0396	ATPase activity
H9N23_11510	COG0719	Fe-S assembly protein
H9N23_11515	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H9N23_11530	COG2146	nitrite reductase [NAD(P)H] activity
H9N23_11565	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
H9N23_11580	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
H9N23_11590	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
H9N23_11595	COG0174	glutamine synthetase
H9N23_11600	COG3328	transposase activity
H9N23_11625	COG0326	Molecular chaperone. Has ATPase activity
H9N23_11630	COG2207	Transcriptional regulator
H9N23_11660	COG0657	acetylesterase activity
H9N23_11660	COG2755	lipolytic protein G-D-S-L family
H9N23_11685	COG0488	(ABC) transporter
H9N23_11720	COG4651	solute:proton antiporter activity
H9N23_11720	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H9N23_11735	COG4772	TonB-dependent receptor
H9N23_11745	COG4264	IucA IucC family
H9N23_11750	COG2814	Major facilitator Superfamily
H9N23_11760	COG0019	diaminopimelate decarboxylase activity
H9N23_11820	COG4206	TonB-dependent receptor
H9N23_11855	COG0542	response to heat
H9N23_11890	COG0534	Mate efflux family protein
H9N23_11905	COG0336	Belongs to the RNA methyltransferase TrmD family
H9N23_11910	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
H9N23_11915	COG0228	four-way junction DNA binding
H9N23_11935	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H9N23_11945	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H9N23_11990	COG1555	photosystem II stabilization
H9N23_11995	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H9N23_12010	COG3178	'Phosphotransferase
H9N23_12015	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
H9N23_12025	COG0628	permease
H9N23_12035	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
H9N23_12050	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H9N23_12070	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H9N23_12075	COG0271	Belongs to the BolA IbaG family
H9N23_12085	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
H9N23_12095	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
H9N23_12100	COG1137	ATPase activity
H9N23_12115	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9N23_12120	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
H9N23_12125	COG1660	Displays ATPase and GTPase activities
H9N23_12135	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9N23_12140	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H9N23_12145	COG2239	Acts as a magnesium transporter
H9N23_12155	COG1294	oxidase, subunit
H9N23_12160	COG1271	oxidase subunit
H9N23_12175	COG1113	amino acid transport
H9N23_12190	COG2197	response regulator
H9N23_12195	COG0531	amino acid
H9N23_12250	COG0754	glutathionylspermidine amidase activity
H9N23_12275	COG1842	Phage shock protein A
H9N23_12290	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
H9N23_12295	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
H9N23_12305	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
H9N23_12375	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
H9N23_12425	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H9N23_12430	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H9N23_12470	COG0745	RESPONSE REGULATOR receiver
H9N23_12475	COG2205	protein histidine kinase activity
H9N23_12495	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H9N23_12525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H9N23_12525	COG3453	Protein conserved in bacteria
H9N23_12530	COG0725	ABC transporter, periplasmic molybdate-binding protein
H9N23_12535	COG4149	molybdate abc transporter
H9N23_12540	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
H9N23_12560	COG0642	Histidine kinase
H9N23_12575	COG1028	Short-chain dehydrogenase reductase Sdr
H9N23_12585	COG1022	Amp-dependent synthetase and ligase
H9N23_12610	COG1376	ErfK ybiS ycfS ynhG family protein
H9N23_12615	COG0739	heme binding
H9N23_12625	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H9N23_12630	COG1301	dicarboxylic acid transport
H9N23_12650	COG2304	oxidoreductase activity
H9N23_12670	COG0714	Associated with various cellular activities
H9N23_12720	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
H9N23_12750	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H9N23_12760	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H9N23_12785	COG1561	YicC-like family, N-terminal region
H9N23_12790	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
H9N23_12805	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H9N23_12845	COG0006	proline dipeptidase activity
H9N23_12870	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H9N23_12890	COG2912	Transglutaminase-like superfamily
H9N23_12895	COG1773	rubredoxin
H9N23_12900	COG0352	thiamine-phosphate diphosphorylase activity
H9N23_12930	COG0281	malic enzyme
H9N23_12930	COG0280	phosphate acetyltransferase
H9N23_12950	COG4191	Histidine kinase
H9N23_12965	COG0583	DNA-binding transcription factor activity
H9N23_12980	COG2197	response regulator
H9N23_12990	COG0642	Histidine kinase
H9N23_13005	COG2851	Citrate transporter
H9N23_13010	COG1028	Short-chain dehydrogenase reductase Sdr
H9N23_13015	COG1609	Transcriptional regulator
H9N23_13025	COG2211	Major facilitator Superfamily
H9N23_13075	COG0726	polysaccharide deacetylase
H9N23_13080	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
H9N23_13105	COG3039	Transposase
H9N23_13150	COG0242	peptide deformylase activity
H9N23_13170	COG0714	Associated with various cellular activities
H9N23_13190	COG0537	adenosine 5'-monophosphoramidase activity
H9N23_13220	COG0314	molybdopterin synthase activity
H9N23_13225	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
H9N23_13230	COG0315	cyclic pyranopterin monophosphate synthase activity
H9N23_13240	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
H9N23_13245	COG1234	tRNA 3'-trailer cleavage
H9N23_13250	COG3642	lipopolysaccharide core region biosynthetic process
H9N23_13255	COG0859	PFAM glycosyl transferase family 9
H9N23_13265	COG0582	viral genome integration into host DNA
H9N23_13335	COG0631	protein serine/threonine phosphatase activity
H9N23_13345	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H9N23_13370	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H9N23_13410	COG0544	peptidyl-prolyl cis-trans isomerase activity
H9N23_13460	COG0473	3-isopropylmalate dehydrogenase activity
H9N23_13485	COG0584	glycerophosphoryl diester phosphodiesterase
H9N23_13505	COG3039	Transposase
H9N23_13635	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
H9N23_13655	COG1217	gtp-binding protein TYPA
H9N23_13660	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H9N23_13670	COG0625	glutathione transferase activity
H9N23_13685	COG3781	membrane
H9N23_13695	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H9N23_13725	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
H9N23_13745	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
H9N23_13770	COG3710	Transcriptional regulator
H9N23_13775	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
H9N23_13785	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
H9N23_13820	COG0066	3-isopropylmalate dehydratase activity
H9N23_13825	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
H9N23_13850	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
H9N23_13855	COG1538	Outer membrane efflux protein
H9N23_13860	COG1519	Transferase
H9N23_13865	COG1560	Kdo2-lipid A biosynthetic process
H9N23_13910	COG0308	aminopeptidase N
H9N23_13925	COG0330	HflC and HflK could
H9N23_13930	COG0330	HflC and HflK could
H9N23_13950	COG0678	peroxiredoxin activity
H9N23_13960	COG2826	transposase and inactivated derivatives, IS30 family
H9N23_14030	COG3829	transcription factor binding
H9N23_14060	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H9N23_14065	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H9N23_14075	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H9N23_14080	COG1028	Short-chain dehydrogenase reductase Sdr
H9N23_14105	COG1399	metal-binding, possibly nucleic acid-binding protein
H9N23_14145	COG1518	maintenance of DNA repeat elements
H9N23_14150	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
H9N23_14205	COG2188	Transcriptional regulator
H9N23_14220	COG1450	Type ii and iii secretion system protein
H9N23_14235	COG3166	PFAM Fimbrial assembly family protein
H9N23_14240	COG3156	type II secretion system protein K
H9N23_14245	COG4795	General secretion pathway protein
H9N23_14250	COG2165	general secretion pathway protein
H9N23_14255	COG4970	Tfp pilus assembly protein FimT
H9N23_14260	COG2165	general secretion pathway protein
H9N23_14265	COG1459	type II secretion system
H9N23_14275	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H9N23_14280	COG1404	Belongs to the peptidase S8 family
H9N23_14305	COG5295	Hep Hag repeat protein
H9N23_14310	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H9N23_14310	COG0047	phosphoribosylformylglycinamidine synthase activity
H9N23_14315	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H9N23_14320	COG4974	Belongs to the 'phage' integrase family
H9N23_14330	COG0795	lipopolysaccharide-transporting ATPase activity
H9N23_14340	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
H9N23_14355	COG0525	valine-tRNA ligase activity
H9N23_14410	COG3039	Transposase
H9N23_14435	COG1183	phosphatidylcholine synthase activity
H9N23_14445	COG0442	prolyl-tRNA aminoacylation
H9N23_14460	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H9N23_14465	COG1127	ABC transporter
H9N23_14470	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H9N23_14470	COG3218	ABC-type transport auxiliary lipoprotein component
H9N23_14505	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H9N23_14510	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
H9N23_14510	COG0662	Cupin 2, conserved barrel domain protein
H9N23_14535	COG2086	electron transfer activity
H9N23_14560	COG3328	transposase activity
H9N23_14600	COG0626	cystathionine gamma-synthase activity
H9N23_14630	COG0625	glutathione transferase activity
H9N23_14640	COG0513	Belongs to the DEAD box helicase family
H9N23_14645	COG0720	synthase
H9N23_14655	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
H9N23_14660	COG1956	GAF domain-containing protein
H9N23_14695	COG0339	signal peptide processing
H9N23_14750	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H9N23_14755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H9N23_14805	COG0355	proton-transporting ATP synthase activity, rotational mechanism
H9N23_14810	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
H9N23_14815	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
H9N23_14820	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
H9N23_14830	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
H9N23_14840	COG0356	it plays a direct role in the translocation of protons across the membrane
H9N23_14860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H9N23_14870	COG0508	dehydrogenase complex catalyzes the overall conversion of
H9N23_14900	COG2011	ABC-type metal ion transport system permease component
H9N23_14910	COG0697	spore germination
H9N23_14945	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H9N23_14950	COG1187	pseudouridine synthase activity
H9N23_14955	COG2813	Specifically methylates the guanine in position
H9N23_14985	COG2202	Pas domain
H9N23_14985	COG2205	protein histidine kinase activity
H9N23_15010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H9N23_15060	COG0745	RESPONSE REGULATOR receiver
H9N23_15075	COG1404	Belongs to the peptidase S8 family
H9N23_15095	COG0842	Transport permease protein
H9N23_15100	COG1131	(ABC) transporter
H9N23_15105	COG0025	NhaP-type Na H and K H
H9N23_15120	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
H9N23_15130	COG1573	uracil-dna glycosylase
H9N23_15140	COG3384	dioxygenase
H9N23_15155	COG0667	Aldo Keto reductase
H9N23_15170	COG3590	peptidase
H9N23_15190	COG0531	amino acid
H9N23_15205	COG2972	Histidine kinase
H9N23_15230	COG2204	response regulator
H9N23_15240	COG1271	oxidase subunit
H9N23_15245	COG1294	oxidase, subunit
H9N23_15465	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H9N23_15475	COG1560	Kdo2-lipid A biosynthetic process
H9N23_15525	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
H9N23_15525	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H9N23_15530	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
H9N23_15535	COG0242	peptide deformylase activity
H9N23_15540	COG1652	LysM domain
H9N23_15545	COG0758	DNA mediated transformation
H9N23_15550	COG2922	Belongs to the Smg family
H9N23_15565	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H9N23_15565	COG1754	DNA topoisomerase type I activity
H9N23_15570	COG0009	L-threonylcarbamoyladenylate synthase
H9N23_15585	COG1028	Short-chain dehydrogenase reductase Sdr
H9N23_15595	COG0616	signal peptide processing
H9N23_15600	COG0534	Mate efflux family protein
H9N23_15620	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H9N23_15655	COG1324	tolerance protein
H9N23_15665	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
H9N23_15670	COG0511	ligase activity, forming carbon-carbon bonds
H9N23_15680	COG0439	Biotin carboxylase
H9N23_15725	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
H9N23_15745	COG2267	carboxylic ester hydrolase activity
H9N23_15750	COG2267	carboxylic ester hydrolase activity
H9N23_15765	COG0419	ATPase involved in DNA repair
H9N23_15775	COG0151	Belongs to the GarS family
H9N23_15780	COG0577	efflux transmembrane transporter activity
H9N23_15780	COG1136	(ABC) transporter
H9N23_15790	COG1289	transmembrane transporter activity
H9N23_15805	COG2814	Major facilitator Superfamily
H9N23_15820	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
H9N23_15860	COG0745	RESPONSE REGULATOR receiver
H9N23_15905	COG0739	heme binding
H9N23_15920	COG2211	Major facilitator Superfamily
H9N23_15925	COG0708	Exodeoxyribonuclease III
H9N23_15940	COG1192	Involved in chromosome partitioning
H9N23_15945	COG1475	DNA binding
H9N23_15960	COG0463	Glycosyl transferase, family 2
H9N23_15985	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H9N23_15990	COG2003	Belongs to the UPF0758 family
H9N23_15995	COG0018	arginyl-trna synthetase
H9N23_16010	COG4221	oxidoreductase activity
H9N23_16035	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H9N23_16040	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H9N23_16055	COG3485	protocatechuate 3,4-dioxygenase
H9N23_16060	COG3485	protocatechuate 3,4-dioxygenase
H9N23_16095	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H9N23_16100	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H9N23_16110	COG0045	succinate-CoA ligase (ADP-forming) activity
H9N23_16110	COG1042	CoA-binding domain protein
H9N23_16110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H9N23_16120	COG2239	Acts as a magnesium transporter
H9N23_16135	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
H9N23_16140	COG3387	PFAM Glycoside hydrolase 15-related
H9N23_16155	COG3100	YcgL domain-containing protein
H9N23_16160	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H9N23_16170	COG0463	Glycosyl transferase, family 2
H9N23_16185	COG1028	Short-chain dehydrogenase reductase Sdr
H9N23_16195	COG0156	8-amino-7-oxononanoate synthase activity
H9N23_16200	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
H9N23_16205	COG1040	competence protein
H9N23_16210	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
H9N23_16220	COG0628	permease
H9N23_16230	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
H9N23_16240	COG1595	DNA-templated transcription, initiation
H9N23_16245	COG0753	catalase activity
H9N23_16290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H9N23_16295	COG0180	Tryptophanyl-tRNA synthetase
H9N23_16300	COG3237	CsbD-like
H9N23_16335	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
H9N23_16350	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
H9N23_16355	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
H9N23_16355	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
H9N23_16395	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H9N23_16420	COG1566	PFAM secretion protein HlyD family protein
H9N23_16440	COG1199	ATP-dependent helicase activity
H9N23_16480	COG0583	DNA-binding transcription factor activity
H9N23_16525	COG0625	glutathione transferase activity
H9N23_16560	COG4555	ABC transporter
H9N23_16570	COG1476	TRANSCRIPTIONal
H9N23_16595	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H9N23_16600	COG1131	(ABC) transporter
H9N23_16605	COG0842	Transport permease protein
H9N23_16615	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
H9N23_16695	COG3039	Transposase
H9N23_16705	COG1181	Belongs to the D-alanine--D-alanine ligase family
H9N23_16715	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
H9N23_16725	COG0564	pseudouridine synthase activity
H9N23_16755	COG0339	signal peptide processing
H9N23_16785	COG3254	rhamnose metabolic process
H9N23_16790	COG0738	Major facilitator superfamily
H9N23_16795	COG1414	Transcriptional regulator
H9N23_16805	COG2205	protein histidine kinase activity
H9N23_16815	COG3459	Glycosyltransferase 36 associated
H9N23_16820	COG2211	Major facilitator Superfamily
H9N23_16825	COG3265	gluconokinase activity
H9N23_16835	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H9N23_16910	COG1127	ABC transporter
H9N23_16915	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H9N23_16920	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H9N23_16935	COG2853	Lipoprotein
H9N23_16955	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
H9N23_17020	COG0676	glucose-6-phosphate 1-epimerase activity
H9N23_17025	COG3039	Transposase
H9N23_17050	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
H9N23_17060	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
H9N23_17070	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
H9N23_17075	COG1064	alcohol dehydrogenase
H9N23_17120	COG1522	sequence-specific DNA binding
H9N23_17125	COG3186	Phenylalanine-4-hydroxylase
H9N23_17160	COG0604	alcohol dehydrogenase
H9N23_17160	COG1028	Short-chain dehydrogenase reductase Sdr
H9N23_17160	COG3321	synthase
H9N23_17165	COG2937	Belongs to the GPAT DAPAT family
H9N23_17200	COG0284	orotidine-5'-phosphate decarboxylase activity
H9N23_17205	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
H9N23_17210	COG3132	Protein of unknown function, DUF480
H9N23_17225	COG0210	DNA helicase
H9N23_17240	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
H9N23_17265	COG1028	Short-chain dehydrogenase reductase Sdr
H9N23_17290	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H9N23_17350	COG1166	arginine decarboxylase activity
H9N23_17355	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
H9N23_17395	COG0606	chelatase, subunit chli
H9N23_17440	COG0366	Alpha amylase catalytic
H9N23_17445	COG0366	Alpha amylase catalytic
H9N23_17470	COG1609	Transcriptional regulator
H9N23_17520	COG0493	'glutamate synthase
H9N23_17525	COG0067	glutamate synthase
H9N23_17525	COG0070	glutamate synthase
H9N23_17525	COG0069	glutamate synthase activity
H9N23_17585	COG1111	helicase
H9N23_17585	COG1205	dead DEAH box helicase
H9N23_17590	COG1272	protein, Hemolysin III
H9N23_17630	COG1136	(ABC) transporter
H9N23_17690	COG2826	transposase and inactivated derivatives, IS30 family
H9N23_17715	COG3039	Transposase
H9N23_17725	COG1090	epimerase
H9N23_17735	COG0642	Histidine kinase
H9N23_17745	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H9N23_17855	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
H9N23_17930	COG3264	Mechanosensitive ion channel
H9N23_17930	COG1511	domain protein
H9N23_17945	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
H9N23_17950	COG2354	Protein conserved in bacteria
H9N23_17955	COG1649	PFAM Uncharacterised BCR, COG1649
H9N23_17975	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
H9N23_18000	COG0702	epimerase
H9N23_18015	COG1858	cytochrome C peroxidase
H9N23_18060	COG3039	Transposase
H9N23_18110	COG0513	Belongs to the DEAD box helicase family
H9N23_18115	COG3039	Transposase
H9N23_18155	COG1136	(ABC) transporter
H9N23_18165	COG3039	Transposase
H9N23_18175	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H9N23_18205	COG1304	FMN binding
H9N23_18210	COG3039	Transposase
H9N23_18225	COG4772	TonB-dependent receptor
H9N23_18235	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
H9N23_18245	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H9N23_18285	COG0501	Belongs to the peptidase M48B family
H9N23_18295	COG0187	DNA topoisomerase II activity
H9N23_18310	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
H9N23_18330	COG0726	polysaccharide deacetylase
H9N23_18340	COG0671	phosphoesterase, PA-phosphatase related
H9N23_18350	COG0584	glycerophosphoryl diester phosphodiesterase
H9N23_18360	COG0861	Integral membrane protein TerC family
H9N23_18365	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
H9N23_18380	COG2271	Major facilitator Superfamily
H9N23_18385	COG1929	Belongs to the glycerate kinase type-1 family
H9N23_18475	COG0477	Major facilitator Superfamily
H9N23_18500	COG0302	gtp cyclohydrolase
H9N23_18505	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
H9N23_18550	COG2234	aminopeptidase activity
H9N23_18560	COG4942	peptidase
H9N23_18565	COG0793	Belongs to the peptidase S41A family
H9N23_18615	COG0386	Belongs to the glutathione peroxidase family
H9N23_18625	COG1322	Protein conserved in bacteria
H9N23_18630	COG0531	amino acid
H9N23_18645	COG0210	DNA helicase
H9N23_18660	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H9N23_18665	COG0583	DNA-binding transcription factor activity
H9N23_18670	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H9N23_18690	COG2159	amidohydrolase
H9N23_18720	COG3540	Alkaline phosphatase
H9N23_18730	COG2091	lysine biosynthetic process via aminoadipic acid
H9N23_18745	COG0708	Exodeoxyribonuclease III
H9N23_18760	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H9N23_18765	COG3162	membrane
H9N23_18805	COG3507	Belongs to the glycosyl hydrolase 43 family
H9N23_18825	COG1028	Short-chain dehydrogenase reductase Sdr
H9N23_18830	COG0179	Fumarylacetoacetate (FAA) hydrolase
H9N23_18835	COG4948	Mandelate Racemase Muconate Lactonizing
H9N23_18840	COG4807	Protein conserved in bacteria
H9N23_18845	COG1643	Atp-dependent helicase
H9N23_18855	COG1187	pseudouridine synthase activity
H9N23_18865	COG0667	Aldo Keto reductase
H9N23_18870	COG2130	NADP-dependent
H9N23_18875	COG0656	L-ascorbic acid biosynthetic process
H9N23_18900	COG3039	Transposase
H9N23_18915	COG1752	Esterase of the alpha-beta hydrolase superfamily
H9N23_18925	COG1119	ATPase activity
H9N23_18940	COG1125	glycine betaine transport
H9N23_18940	COG0517	IMP dehydrogenase activity
H9N23_18955	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H9N23_18960	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
H9N23_18965	COG3550	peptidyl-serine autophosphorylation
H9N23_18970	COG1396	sequence-specific DNA binding
H9N23_18990	COG0489	protein tyrosine kinase activity
H9N23_18995	COG2062	phosphohistidine phosphatase, SixA
H9N23_19005	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H9N23_19050	COG1968	undecaprenyl-diphosphatase activity
H9N23_19055	COG0174	glutamine synthetase
H9N23_19060	COG0347	Belongs to the P(II) protein family
H9N23_19065	COG0004	ammonium transporteR
H9N23_19070	COG3852	Histidine kinase
H9N23_19075	COG2204	response regulator
H9N23_19080	COG2032	superoxide dismutase activity
H9N23_19085	COG2032	superoxide dismutase activity
H9N23_19130	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
H9N23_19135	COG1074	ATP-dependent DNA helicase activity
H9N23_19145	COG3549	Plasmid maintenance system killer
H9N23_19225	COG1764	response to oxidative stress
H9N23_19230	COG1846	Transcriptional regulator
H9N23_19275	COG4943	cyclic-guanylate-specific phosphodiesterase activity
H9N23_19325	COG2211	Major facilitator Superfamily
H9N23_19345	COG3693	PFAM glycoside hydrolase, family 10
H9N23_19370	COG0246	Mannitol dehydrogenase
H9N23_19375	COG1472	Belongs to the glycosyl hydrolase 3 family
H9N23_19385	COG4948	Mandelate Racemase Muconate Lactonizing
H9N23_19395	COG3661	Belongs to the glycosyl hydrolase 67 family
H9N23_19440	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
H9N23_19450	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H9N23_19460	COG0805	protein transport
H9N23_19470	COG0519	Catalyzes the synthesis of GMP from XMP
H9N23_19470	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H9N23_19485	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H9N23_19500	COG0457	Tetratricopeptide repeat
H9N23_19505	COG4771	TonB-dependent receptor
H9N23_19520	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
H9N23_19530	COG0697	spore germination
H9N23_19540	COG0523	cobalamin synthesis protein
H9N23_19595	COG1960	acyl-CoA dehydrogenase activity
H9N23_19600	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H9N23_19605	COG4770	biotin carboxylase activity
H9N23_19655	COG2072	flavoprotein involved in K transport
H9N23_19675	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
H9N23_19725	COG0084	hydrolase, TatD family'
H9N23_19740	COG0583	DNA-binding transcription factor activity
H9N23_19745	COG2814	Major facilitator Superfamily
H9N23_19755	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H9N23_19760	COG1902	pentaerythritol trinitrate reductase activity
H9N23_19790	COG0745	RESPONSE REGULATOR receiver
H9N23_19810	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H9N23_19815	COG0583	DNA-binding transcription factor activity
H9N23_19845	COG0702	epimerase
H9N23_19850	COG1733	regulation of RNA biosynthetic process
H9N23_19905	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H9N23_19920	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H9N23_19955	COG2911	Protein conserved in bacteria
H9N23_19960	COG0729	surface antigen
H9N23_19975	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
H9N23_19980	COG3118	belongs to the thioredoxin family
H9N23_19990	COG2884	Cell division ATP-binding protein ftsE
H9N23_19995	COG2177	Part of the ABC transporter FtsEX involved in
H9N23_20000	COG2201	protein-glutamate methylesterase activity
H9N23_20005	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
H9N23_20010	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H9N23_20020	COG1252	NADH dehydrogenase
H9N23_20045	COG0459	protein refolding
H9N23_20055	COG4771	TonB-dependent receptor
H9N23_20070	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H9N23_20115	COG3386	PFAM SMP-30 Gluconolaconase
H9N23_20130	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
H9N23_20160	COG2353	YceI-like domain
H9N23_20255	COG0408	coproporphyrinogen oxidase activity
H9N23_20265	COG3039	Transposase
H9N23_20290	COG0129	dihydroxy-acid dehydratase activity
H9N23_20300	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H9N23_20350	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H9N23_20355	COG0318	PFAM AMP-dependent synthetase and ligase
H9N23_20360	COG0727	PFAM Uncharacterised protein family (UPF0153)
H9N23_20365	COG0596	Alpha beta hydrolase
H9N23_20380	COG3177	Filamentation induced by cAMP protein fic
H9N23_20385	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H9N23_20400	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H9N23_20425	COG4191	Histidine kinase
H9N23_20430	COG0028	Belongs to the TPP enzyme family
H9N23_20445	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
H9N23_20450	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H9N23_20485	COG5383	Protein conserved in bacteria
H9N23_20495	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H9N23_20500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H9N23_20505	COG1473	amidohydrolase
H9N23_20515	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
H9N23_20515	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
H9N23_20520	COG3328	transposase activity
H9N23_20580	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H9N23_20595	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H9N23_20600	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
H9N23_20610	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
H9N23_20615	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
H9N23_20620	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H9N23_20670	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H9N23_20670	COG1565	acr, cog1565
H9N23_20685	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
H9N23_20750	COG0358	DNA primase activity
H9N23_20755	COG1295	ribonuclease BN
H9N23_20765	COG1610	YqeY-like protein
H9N23_20775	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
H9N23_20780	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
H9N23_20815	COG2133	pyrroloquinoline quinone binding
H9N23_20820	COG4682	membrane
H9N23_20855	COG0531	amino acid
H9N23_20890	COG4948	Mandelate Racemase Muconate Lactonizing
H9N23_20900	COG3023	N-Acetylmuramoyl-L-alanine amidase
H9N23_20905	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
H9N23_20935	COG3039	Transposase
H9N23_20985	COG0183	Belongs to the thiolase family
H9N23_21020	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H9N23_21030	COG3483	tryptophan 2,3-dioxygenase activity
H9N23_21035	COG3104	oligopeptide transport
H9N23_21055	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
H9N23_21065	COG1320	monovalent cation:proton antiporter activity
H9N23_21070	COG2212	antiporter activity
H9N23_21080	COG0651	ATP synthesis coupled electron transport
H9N23_21085	COG1006	Multisubunit Na H antiporter MnhC subunit
H9N23_21090	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H9N23_21090	COG2111	Na H antiporter
H9N23_21120	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
H9N23_21130	COG0456	acetyltransferase
H9N23_21160	COG4221	oxidoreductase activity
H9N23_21220	COG0697	spore germination
H9N23_21225	COG4305	rare lipoprotein A
H9N23_21230	COG5297	Belongs to the glycosyl hydrolase family 6
H9N23_21240	COG1113	amino acid transport
H9N23_21250	COG0598	Magnesium transport protein CorA
H9N23_21320	COG5297	Belongs to the glycosyl hydrolase family 6
H9N23_21320	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
H9N23_21325	COG0659	secondary active sulfate transmembrane transporter activity
H9N23_21360	COG3275	phosphorelay sensor kinase activity
H9N23_21370	COG0181	hydroxymethylbilane synthase activity
H9N23_21395	COG1505	serine-type exopeptidase activity
H9N23_21410	COG0436	Aminotransferase
H9N23_21440	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
H9N23_21470	COG0308	aminopeptidase N
H9N23_21475	COG2199	diguanylate cyclase activity
H9N23_21525	COG3039	Transposase
H9N23_21530	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H9N23_21535	COG1077	Cell shape determining protein MreB Mrl
H9N23_21540	COG1792	Involved in formation and maintenance of cell shape
H9N23_21555	COG0772	Belongs to the SEDS family
H9N23_21620	COG2951	lytic endotransglycosylase activity
H9N23_21625	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H9N23_21630	COG1686	Belongs to the peptidase S11 family
H9N23_21645	COG2921	Belongs to the UPF0250 family
H9N23_21685	COG1051	belongs to the nudix hydrolase family
H9N23_21685	COG1056	cytidyltransferase-related domain
H9N23_21720	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
H9N23_21725	COG0673	inositol 2-dehydrogenase activity
H9N23_21730	COG2823	Periplasmic or secreted lipoprotein
H9N23_21735	COG4251	negative regulation of phosphorylation
H9N23_21740	COG0784	Response regulator, receiver
H9N23_21745	COG4191	Histidine kinase
H9N23_21750	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H9N23_21790	COG3250	beta-galactosidase activity
H9N23_21805	COG2188	Transcriptional regulator
H9N23_21815	COG1609	Transcriptional regulator
H9N23_21820	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H9N23_21825	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
H9N23_21835	COG1215	transferase activity, transferring glycosyl groups
H9N23_21840	COG0726	polysaccharide deacetylase
H9N23_21840	COG1649	PFAM Uncharacterised BCR, COG1649
H9N23_21890	COG3039	Transposase
H9N23_21945	COG3039	Transposase
H9N23_21955	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H9N23_21960	COG3039	Transposase
H9N23_21995	COG0218	Necessary for normal cell division and for the maintenance of normal septation
H9N23_22015	COG2205	protein histidine kinase activity
H9N23_22050	COG2205	protein histidine kinase activity
H9N23_22100	COG0488	(ABC) transporter
H9N23_22120	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
H9N23_22140	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H9N23_22140	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H9N23_22160	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
H9N23_22165	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H9N23_22170	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
H9N23_22190	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
H9N23_22195	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
H9N23_22205	COG2205	protein histidine kinase activity
H9N23_22210	COG0745	RESPONSE REGULATOR receiver
H9N23_22215	COG0277	FAD linked oxidase domain protein
H9N23_22220	COG1988	membrane-bound metal-dependent
H9N23_22225	COG0792	nuclease activity
H9N23_22260	COG0275	rRNA processing
H9N23_22265	COG3116	cell division
H9N23_22280	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H9N23_22300	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H9N23_22305	COG1181	Belongs to the D-alanine--D-alanine ligase family
H9N23_22310	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H9N23_22325	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
H9N23_22335	COG1388	LysM domain
H9N23_22335	COG4942	peptidase
H9N23_22350	COG0494	nUDIX hydrolase
H9N23_22370	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H9N23_22380	COG3321	synthase
H9N23_22380	COG1028	Short-chain dehydrogenase reductase Sdr
H9N23_22380	COG0604	alcohol dehydrogenase
H9N23_22425	COG2226	methyltransferase
H9N23_22430	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
H9N23_22465	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
H9N23_22480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H9N23_22490	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H9N23_22495	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H9N23_22505	COG0667	Aldo Keto reductase
H9N23_22545	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
H9N23_22555	COG2175	clavaminate synthase activity
H9N23_22565	COG4181	ATPase activity
H9N23_22580	COG0642	Histidine kinase
H9N23_22600	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
H9N23_22620	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
H9N23_22645	COG2967	ApaG domain
H9N23_22650	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H9N23_22660	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
H9N23_22675	COG0123	including yeast histone deacetylase and acetoin utilization protein
H9N23_22680	COG2096	Adenosyltransferase
H9N23_22690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H9N23_22695	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H9N23_22735	COG0583	DNA-binding transcription factor activity
H9N23_22740	COG0318	PFAM AMP-dependent synthetase and ligase
H9N23_22750	COG1024	Enoyl-CoA hydratase
H9N23_22770	COG3386	PFAM SMP-30 Gluconolaconase
H9N23_22900	COG0446	pyridine nucleotide-disulphide oxidoreductase
H9N23_22900	COG1902	pentaerythritol trinitrate reductase activity
H9N23_22905	COG0604	alcohol dehydrogenase
H9N23_22930	COG0156	8-amino-7-oxononanoate synthase activity
H9N23_22935	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
H9N23_22940	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
H9N23_22945	COG4208	sulfate ABC transporter
H9N23_22950	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
H9N23_22980	COG0406	alpha-ribazole phosphatase activity
H9N23_22990	COG0285	dihydrofolate synthase activity
H9N23_23010	COG2833	Protein of unknown function (DUF455)
H9N23_23030	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H9N23_23035	COG0671	phosphoesterase, PA-phosphatase related
H9N23_23040	COG0438	transferase activity, transferring glycosyl groups
H9N23_23050	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)