locus-tag	class	description
EBA04_00025	COG0187	DNA topoisomerase II activity
EBA04_00035	COG0501	Belongs to the peptidase M48B family
EBA04_00065	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EBA04_00095	COG3039	Transposase
EBA04_00145	COG0793	Belongs to the peptidase S41A family
EBA04_00150	COG4942	peptidase
EBA04_00160	COG2234	aminopeptidase activity
EBA04_00170	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA04_00185	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA04_00195	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA04_00205	COG1064	alcohol dehydrogenase
EBA04_00230	COG0493	'glutamate synthase
EBA04_00235	COG0070	glutamate synthase
EBA04_00235	COG0069	glutamate synthase activity
EBA04_00235	COG0067	glutamate synthase
EBA04_00305	COG1111	helicase
EBA04_00305	COG1205	dead DEAH box helicase
EBA04_00310	COG1272	protein, Hemolysin III
EBA04_00340	COG2032	superoxide dismutase activity
EBA04_00345	COG2204	response regulator
EBA04_00350	COG3852	Histidine kinase
EBA04_00355	COG0004	ammonium transporteR
EBA04_00360	COG0347	Belongs to the P(II) protein family
EBA04_00365	COG0174	glutamine synthetase
EBA04_00420	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EBA04_00430	COG2062	phosphohistidine phosphatase, SixA
EBA04_00435	COG0489	protein tyrosine kinase activity
EBA04_00455	COG1396	sequence-specific DNA binding
EBA04_00460	COG3550	peptidyl-serine autophosphorylation
EBA04_00465	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
EBA04_00470	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EBA04_00485	COG0517	IMP dehydrogenase activity
EBA04_00485	COG1125	glycine betaine transport
EBA04_00500	COG1119	ATPase activity
EBA04_00515	COG1752	Esterase of the alpha-beta hydrolase superfamily
EBA04_00525	COG1522	sequence-specific DNA binding
EBA04_00530	COG3186	Phenylalanine-4-hydroxylase
EBA04_00560	COG1609	Transcriptional regulator
EBA04_00600	COG0366	Alpha amylase catalytic
EBA04_00605	COG0366	Alpha amylase catalytic
EBA04_00615	COG3039	Transposase
EBA04_00625	COG0183	Belongs to the thiolase family
EBA04_00665	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EBA04_00670	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EBA04_00685	COG0028	Belongs to the TPP enzyme family
EBA04_00690	COG4191	Histidine kinase
EBA04_00715	COG3039	Transposase
EBA04_00725	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EBA04_00740	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EBA04_00745	COG3177	Filamentation induced by cAMP protein fic
EBA04_00750	COG0596	Alpha beta hydrolase
EBA04_00765	COG0318	PFAM AMP-dependent synthetase and ligase
EBA04_00770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EBA04_00785	COG1181	Belongs to the D-alanine--D-alanine ligase family
EBA04_00815	COG0564	pseudouridine synthase activity
EBA04_00845	COG0339	signal peptide processing
EBA04_00900	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EBA04_00905	COG1960	acyl-CoA dehydrogenase activity
EBA04_00960	COG0697	spore germination
EBA04_00970	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EBA04_00975	COG1846	Transcriptional regulator
EBA04_00980	COG1764	response to oxidative stress
EBA04_01005	COG3501	Rhs element vgr protein
EBA04_01030	COG0656	L-ascorbic acid biosynthetic process
EBA04_01045	COG2130	NADP-dependent
EBA04_01060	COG1187	pseudouridine synthase activity
EBA04_01075	COG1643	Atp-dependent helicase
EBA04_01085	COG4807	Protein conserved in bacteria
EBA04_01090	COG2072	flavoprotein involved in K transport
EBA04_01110	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EBA04_01115	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EBA04_01155	COG3039	Transposase
EBA04_01200	COG0084	hydrolase, TatD family'
EBA04_01220	COG0583	DNA-binding transcription factor activity
EBA04_01225	COG2814	Major facilitator Superfamily
EBA04_01235	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EBA04_01240	COG1902	pentaerythritol trinitrate reductase activity
EBA04_01270	COG0745	RESPONSE REGULATOR receiver
EBA04_01290	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EBA04_01295	COG0583	DNA-binding transcription factor activity
EBA04_01325	COG0702	epimerase
EBA04_01330	COG1733	regulation of RNA biosynthetic process
EBA04_01365	COG3039	Transposase
EBA04_01385	COG3501	Rhs element vgr protein
EBA04_01410	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EBA04_01480	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EBA04_01485	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EBA04_01495	COG3485	protocatechuate 3,4-dioxygenase
EBA04_01500	COG3485	protocatechuate 3,4-dioxygenase
EBA04_01515	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EBA04_01520	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EBA04_01535	COG1414	Transcriptional regulator
EBA04_01625	COG1040	competence protein
EBA04_01630	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EBA04_01735	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EBA04_01810	COG3264	Mechanosensitive ion channel
EBA04_01810	COG1511	domain protein
EBA04_01820	COG3039	Transposase
EBA04_01825	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EBA04_01835	COG2354	Protein conserved in bacteria
EBA04_01845	COG0745	RESPONSE REGULATOR receiver
EBA04_01845	COG3706	GGDEF domain
EBA04_01860	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EBA04_01885	COG0702	epimerase
EBA04_01895	COG1028	Short-chain dehydrogenase reductase Sdr
EBA04_01940	COG0513	Belongs to the DEAD box helicase family
EBA04_01950	COG3039	Transposase
EBA04_01980	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EBA04_01995	COG3104	oligopeptide transport
EBA04_02025	COG1320	monovalent cation:proton antiporter activity
EBA04_02030	COG2212	antiporter activity
EBA04_02040	COG0651	ATP synthesis coupled electron transport
EBA04_02045	COG1006	Multisubunit Na H antiporter MnhC subunit
EBA04_02050	COG2111	Na H antiporter
EBA04_02050	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EBA04_02085	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EBA04_02095	COG0456	acetyltransferase
EBA04_02140	COG0134	indole-3-glycerol-phosphate synthase activity
EBA04_02150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EBA04_02195	COG2906	2 iron, 2 sulfur cluster binding
EBA04_02245	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
EBA04_02265	COG2814	Major facilitator Superfamily
EBA04_02275	COG2814	Major facilitator Superfamily
EBA04_02280	COG1289	transmembrane transporter activity
EBA04_02290	COG0151	Belongs to the GarS family
EBA04_02295	COG0138	bifunctional purine biosynthesis protein purh
EBA04_02300	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EBA04_02310	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EBA04_02365	COG0439	Biotin carboxylase
EBA04_02375	COG0511	ligase activity, forming carbon-carbon bonds
EBA04_02395	COG1324	tolerance protein
EBA04_02415	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EBA04_02435	COG0534	Mate efflux family protein
EBA04_02440	COG0616	signal peptide processing
EBA04_02450	COG1028	Short-chain dehydrogenase reductase Sdr
EBA04_02470	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EBA04_02470	COG1754	DNA topoisomerase type I activity
EBA04_02490	COG0758	DNA mediated transformation
EBA04_02495	COG1652	LysM domain
EBA04_02500	COG0242	peptide deformylase activity
EBA04_02510	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EBA04_02510	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EBA04_02560	COG1560	Kdo2-lipid A biosynthetic process
EBA04_02570	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EBA04_02600	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EBA04_02605	COG3118	belongs to the thioredoxin family
EBA04_02615	COG2884	Cell division ATP-binding protein ftsE
EBA04_02620	COG2177	Part of the ABC transporter FtsEX involved in
EBA04_02625	COG3437	response regulator, receiver
EBA04_02635	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EBA04_02640	COG2860	membrane
EBA04_02645	COG1252	NADH dehydrogenase
EBA04_02665	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EBA04_02685	COG3039	Transposase
EBA04_02695	COG3039	Transposase
EBA04_02705	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EBA04_02720	COG3386	PFAM SMP-30 Gluconolaconase
EBA04_02735	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EBA04_02780	COG2353	YceI-like domain
EBA04_02835	COG3501	Rhs element vgr protein
EBA04_02895	COG4221	oxidoreductase activity
EBA04_02950	COG0697	spore germination
EBA04_02955	COG4305	rare lipoprotein A
EBA04_02960	COG5297	Belongs to the glycosyl hydrolase family 6
EBA04_02970	COG1113	amino acid transport
EBA04_02980	COG0598	Magnesium transport protein CorA
EBA04_03060	COG3300	MHYT domain
EBA04_03060	COG5001	Diguanylate cyclase
EBA04_03085	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA04_03085	COG5297	Belongs to the glycosyl hydrolase family 6
EBA04_03090	COG0659	secondary active sulfate transmembrane transporter activity
EBA04_03095	COG3706	GGDEF domain
EBA04_03125	COG3275	phosphorelay sensor kinase activity
EBA04_03160	COG1505	serine-type exopeptidase activity
EBA04_03180	COG2832	Protein of unknown function (DUF454)
EBA04_03200	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EBA04_03210	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EBA04_03245	COG3300	MHYT domain
EBA04_03245	COG5001	Diguanylate cyclase
EBA04_03250	COG0308	aminopeptidase N
EBA04_03270	COG1077	Cell shape determining protein MreB Mrl
EBA04_03275	COG1792	Involved in formation and maintenance of cell shape
EBA04_03290	COG0772	Belongs to the SEDS family
EBA04_03315	COG2951	lytic endotransglycosylase activity
EBA04_03320	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EBA04_03325	COG1686	Belongs to the peptidase S11 family
EBA04_03365	COG1056	cytidyltransferase-related domain
EBA04_03365	COG1051	belongs to the nudix hydrolase family
EBA04_03400	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EBA04_03405	COG0673	inositol 2-dehydrogenase activity
EBA04_03410	COG2823	Periplasmic or secreted lipoprotein
EBA04_03415	COG4251	negative regulation of phosphorylation
EBA04_03420	COG0784	Response regulator, receiver
EBA04_03425	COG4191	Histidine kinase
EBA04_03430	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EBA04_03455	COG3039	Transposase
EBA04_03475	COG3250	beta-galactosidase activity
EBA04_03500	COG1609	Transcriptional regulator
EBA04_03505	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EBA04_03510	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EBA04_03525	COG1215	transferase activity, transferring glycosyl groups
EBA04_03530	COG0726	polysaccharide deacetylase
EBA04_03530	COG1649	PFAM Uncharacterised BCR, COG1649
EBA04_03550	COG3039	Transposase
EBA04_03635	COG2205	protein histidine kinase activity
EBA04_03640	COG0745	RESPONSE REGULATOR receiver
EBA04_03665	COG3791	Glutathione-dependent formaldehyde-activating
EBA04_03680	COG3039	Transposase
EBA04_03695	COG0488	(ABC) transporter
EBA04_03725	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EBA04_03735	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EBA04_03735	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EBA04_03765	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EBA04_03795	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EBA04_03800	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EBA04_03810	COG2205	protein histidine kinase activity
EBA04_03815	COG0745	RESPONSE REGULATOR receiver
EBA04_03845	COG0277	FAD linked oxidase domain protein
EBA04_03900	COG3116	cell division
EBA04_03915	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EBA04_03920	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EBA04_03940	COG1181	Belongs to the D-alanine--D-alanine ligase family
EBA04_03945	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EBA04_03970	COG1196	nuclear chromosome segregation
EBA04_03970	COG0741	lytic transglycosylase activity
EBA04_03970	COG0739	heme binding
EBA04_03985	COG0494	nUDIX hydrolase
EBA04_04000	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EBA04_04015	COG3321	synthase
EBA04_04015	COG1028	Short-chain dehydrogenase reductase Sdr
EBA04_04015	COG0604	alcohol dehydrogenase
EBA04_04075	COG2226	methyltransferase
EBA04_04105	COG2826	transposase and inactivated derivatives, IS30 family
EBA04_04130	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EBA04_04145	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EBA04_04155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBA04_04160	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EBA04_04170	COG0667	Aldo Keto reductase
EBA04_04200	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EBA04_04210	COG2175	clavaminate synthase activity
EBA04_04220	COG4181	ATPase activity
EBA04_04235	COG0642	Histidine kinase
EBA04_04250	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EBA04_04290	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EBA04_04315	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EBA04_04330	COG0123	including yeast histone deacetylase and acetoin utilization protein
EBA04_04335	COG2096	Adenosyltransferase
EBA04_04350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EBA04_04355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EBA04_04375	COG1802	Transcriptional regulator
EBA04_04385	COG3384	dioxygenase
EBA04_04390	COG0583	DNA-binding transcription factor activity
EBA04_04395	COG0318	PFAM AMP-dependent synthetase and ligase
EBA04_04405	COG1024	Enoyl-CoA hydratase
EBA04_04425	COG3386	PFAM SMP-30 Gluconolaconase
EBA04_04475	COG2197	response regulator
EBA04_04485	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EBA04_04490	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EBA04_04495	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EBA04_04505	COG0583	DNA-binding transcription factor activity
EBA04_04510	COG3634	alkyl hydroperoxide reductase activity
EBA04_04520	COG2890	protein-(glutamine-N5) methyltransferase activity
EBA04_04560	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EBA04_04560	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EBA04_04575	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EBA04_04600	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EBA04_04605	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EBA04_04630	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EBA04_04640	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EBA04_04670	COG1295	ribonuclease BN
EBA04_04675	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EBA04_04680	COG1254	Belongs to the acylphosphatase family
EBA04_04695	COG0521	Mo-molybdopterin cofactor biosynthetic process
EBA04_04710	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EBA04_04735	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EBA04_04750	COG0012	GTP binding
EBA04_04780	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EBA04_04785	COG0250	Participates in transcription elongation, termination and antitermination
EBA04_04800	COG0081	regulation of translation
EBA04_04805	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EBA04_04825	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EBA04_04850	COG0051	transcription antitermination factor activity, RNA binding
EBA04_04865	COG0089	rRNA binding
EBA04_04870	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EBA04_04890	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EBA04_04895	COG0255	Belongs to the universal ribosomal protein uL29 family
EBA04_04900	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EBA04_04910	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EBA04_04920	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EBA04_04940	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EBA04_04945	COG1841	ribosomal large subunit assembly
EBA04_04950	COG0200	Binds to the 23S rRNA
EBA04_04955	COG0201	protein transport
EBA04_04960	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EBA04_04975	COG0202	RNA polymerase activity
EBA04_04980	COG0203	ribosomal protein L17
EBA04_04995	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
EBA04_05020	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EBA04_05030	COG0625	glutathione transferase activity
EBA04_05060	COG3039	Transposase
EBA04_05080	COG0446	pyridine nucleotide-disulphide oxidoreductase
EBA04_05080	COG1902	pentaerythritol trinitrate reductase activity
EBA04_05085	COG0604	alcohol dehydrogenase
EBA04_05115	COG0156	8-amino-7-oxononanoate synthase activity
EBA04_05120	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EBA04_05125	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EBA04_05130	COG4208	sulfate ABC transporter
EBA04_05135	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EBA04_05145	COG1063	alcohol dehydrogenase
EBA04_05170	COG0406	alpha-ribazole phosphatase activity
EBA04_05180	COG0285	dihydrofolate synthase activity
EBA04_05200	COG2833	Protein of unknown function (DUF455)
EBA04_05230	COG0671	phosphoesterase, PA-phosphatase related
EBA04_05235	COG0438	transferase activity, transferring glycosyl groups
EBA04_05245	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EBA04_05250	COG5002	protein histidine kinase activity
EBA04_05260	COG4783	chaperone-mediated protein folding
EBA04_05275	COG0473	3-isopropylmalate dehydrogenase activity
EBA04_05320	COG3039	Transposase
EBA04_05345	COG0544	peptidyl-prolyl cis-trans isomerase activity
EBA04_05350	COG0740	serine-type endopeptidase activity
EBA04_05385	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EBA04_05410	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EBA04_05425	COG0631	protein serine/threonine phosphatase activity
EBA04_05460	COG0859	PFAM glycosyl transferase family 9
EBA04_05470	COG1234	tRNA 3'-trailer cleavage
EBA04_05475	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EBA04_05490	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EBA04_05495	COG0314	molybdopterin synthase activity
EBA04_05530	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EBA04_05540	COG0537	adenosine 5'-monophosphoramidase activity
EBA04_05560	COG0714	Associated with various cellular activities
EBA04_05580	COG1399	metal-binding, possibly nucleic acid-binding protein
EBA04_05605	COG1028	Short-chain dehydrogenase reductase Sdr
EBA04_05620	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EBA04_05625	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EBA04_05660	COG3829	transcription factor binding
EBA04_05700	COG3039	Transposase
EBA04_05775	COG0330	HflC and HflK could
EBA04_05780	COG0330	HflC and HflK could
EBA04_05790	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EBA04_05795	COG0308	aminopeptidase N
EBA04_05810	COG0732	type I restriction modification DNA specificity domain
EBA04_05825	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
EBA04_05865	COG0406	alpha-ribazole phosphatase activity
EBA04_05865	COG0328	RNA-DNA hybrid ribonuclease activity
EBA04_05910	COG0587	DNA-directed DNA polymerase activity
EBA04_05930	COG1297	OPT oligopeptide transporter protein
EBA04_05945	COG0823	Involved in the tonB-independent uptake of proteins
EBA04_05945	COG1506	peptidase
EBA04_05955	COG2207	Transcriptional regulator
EBA04_05955	COG1917	Cupin 2, conserved barrel domain protein
EBA04_06000	COG0753	catalase activity
EBA04_06040	COG3551	Protein conserved in bacteria
EBA04_06070	COG2194	sulfuric ester hydrolase activity
EBA04_06080	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EBA04_06085	COG0745	RESPONSE REGULATOR receiver
EBA04_06090	COG0642	Histidine kinase
EBA04_06100	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EBA04_06105	COG2894	cell division
EBA04_06120	COG4585	Histidine kinase
EBA04_06125	COG2197	response regulator
EBA04_06140	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EBA04_06165	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EBA04_06230	COG3501	Rhs element vgr protein
EBA04_06240	COG2826	transposase and inactivated derivatives, IS30 family
EBA04_06265	COG3039	Transposase
EBA04_06380	COG3501	Rhs element vgr protein
EBA04_06445	COG1842	Phage shock protein A
EBA04_06470	COG0754	glutathionylspermidine amidase activity
EBA04_06550	COG0531	amino acid
EBA04_06555	COG2197	response regulator
EBA04_06570	COG1113	amino acid transport
EBA04_06600	COG3039	Transposase
EBA04_06610	COG1294	oxidase, subunit
EBA04_06620	COG2239	Acts as a magnesium transporter
EBA04_06630	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EBA04_06635	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EBA04_06650	COG3039	Transposase
EBA04_06675	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EBA04_06690	COG1137	ATPase activity
EBA04_06695	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EBA04_06705	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EBA04_06715	COG0271	Belongs to the BolA IbaG family
EBA04_06720	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EBA04_06745	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EBA04_06770	COG0628	permease
EBA04_06780	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EBA04_06785	COG3178	'Phosphotransferase
EBA04_06795	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EBA04_06800	COG1555	photosystem II stabilization
EBA04_06820	COG3039	Transposase
EBA04_06840	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EBA04_06845	COG0719	Fe-S assembly protein
EBA04_06850	COG0396	ATPase activity
EBA04_06855	COG0719	Fe-S assembly protein
EBA04_06860	COG1959	2 iron, 2 sulfur cluster binding
EBA04_06915	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EBA04_06950	COG0519	Catalyzes the synthesis of GMP from XMP
EBA04_06965	COG1678	Uncharacterized ACR, COG1678
EBA04_06975	COG0540	Belongs to the ATCase OTCase family
EBA04_06985	COG1764	response to oxidative stress
EBA04_06995	COG0384	phenazine biosynthesis protein PhzF
EBA04_07005	COG0527	aspartate kinase activity
EBA04_07035	COG3039	Transposase
EBA04_07045	COG0142	geranyltranstransferase activity
EBA04_07050	COG0629	single-stranded DNA binding
EBA04_07060	COG3706	GGDEF domain
EBA04_07060	COG2203	Gaf domain
EBA04_07060	COG5001	Diguanylate cyclase
EBA04_07060	COG4251	negative regulation of phosphorylation
EBA04_07105	COG2879	small protein
EBA04_07110	COG1966	Carbon starvation protein
EBA04_07115	COG1741	Belongs to the pirin family
EBA04_07125	COG3501	Rhs element vgr protein
EBA04_07210	COG1515	deoxyribonuclease V activity
EBA04_07230	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EBA04_07235	COG2200	EAL domain
EBA04_07235	COG2202	Pas domain
EBA04_07235	COG2199	diguanylate cyclase activity
EBA04_07240	COG0835	chemotaxis
EBA04_07245	COG0840	transmembrane signaling receptor activity
EBA04_07255	COG0643	Histidine kinase
EBA04_07255	COG2198	Histidine kinase
EBA04_07265	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EBA04_07275	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EBA04_07315	COG0735	belongs to the Fur family
EBA04_07345	COG2826	transposase and inactivated derivatives, IS30 family
EBA04_07435	COG3039	Transposase
EBA04_07500	COG5001	Diguanylate cyclase
EBA04_07500	COG5002	protein histidine kinase activity
EBA04_07505	COG1187	pseudouridine synthase activity
EBA04_07530	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EBA04_07535	COG0475	glutathione-regulated potassium exporter activity
EBA04_07540	COG5002	protein histidine kinase activity
EBA04_07540	COG5000	phosphorelay sensor kinase activity
EBA04_07545	COG0745	RESPONSE REGULATOR receiver
EBA04_07550	COG1538	Outer membrane efflux protein
EBA04_07575	COG1132	(ABC) transporter
EBA04_07600	COG3039	Transposase
EBA04_07645	COG3118	belongs to the thioredoxin family
EBA04_07675	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EBA04_07695	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EBA04_07720	COG2968	Membrane
EBA04_07730	COG1530	ribonuclease E activity
EBA04_07735	COG3164	Protein of unknown function
EBA04_07745	COG0312	modulator of DNA gyrase
EBA04_07750	COG3028	Belongs to the UPF0307 family
EBA04_07755	COG0312	modulator of DNA gyrase
EBA04_07770	COG4104	PAAR repeat-containing protein
EBA04_07780	COG0142	geranyltranstransferase activity
EBA04_07785	COG1722	exodeoxyribonuclease VII activity
EBA04_07790	COG0037	tRNA processing
EBA04_07795	COG1785	Belongs to the alkaline phosphatase family
EBA04_07800	COG1301	dicarboxylic acid transport
EBA04_07805	COG4106	trans-aconitate 2-methyltransferase activity
EBA04_07815	COG0791	NLP P60 protein
EBA04_07820	COG0791	NLP P60 protein
EBA04_07825	COG1047	Peptidyl-prolyl cis-trans
EBA04_07830	COG2311	Membrane
EBA04_07835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA04_07865	COG3039	Transposase
EBA04_07875	COG2826	transposase and inactivated derivatives, IS30 family
EBA04_07905	COG2826	transposase and inactivated derivatives, IS30 family
EBA04_07910	COG3039	Transposase
EBA04_07925	COG0489	protein tyrosine kinase activity
EBA04_07935	COG0717	Belongs to the dCTP deaminase family
EBA04_07950	COG3039	Transposase
EBA04_07970	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EBA04_07980	COG3039	Transposase
EBA04_07990	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EBA04_08005	COG2826	transposase and inactivated derivatives, IS30 family
EBA04_08015	COG0433	COG0433 Predicted ATPase
EBA04_08045	COG2890	protein-(glutamine-N5) methyltransferase activity
EBA04_08055	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EBA04_08060	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EBA04_08095	COG0133	tryptophan synthase activity
EBA04_08170	COG1028	Short-chain dehydrogenase reductase Sdr
EBA04_08190	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EBA04_08210	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EBA04_08215	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EBA04_08220	COG1034	ATP synthesis coupled electron transport
EBA04_08225	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EBA04_08230	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EBA04_08240	COG0713	ATP synthesis coupled electron transport
EBA04_08255	COG1007	ATP synthesis coupled electron transport
EBA04_08270	COG0195	Participates in both transcription termination and antitermination
EBA04_08275	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EBA04_08290	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EBA04_08325	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EBA04_08330	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EBA04_08340	COG2095	MarC family integral membrane protein
EBA04_08355	COG3039	Transposase
EBA04_08360	COG1611	Belongs to the LOG family
EBA04_08405	COG4969	Belongs to the N-Me-Phe pilin family
EBA04_08410	COG0556	nucleotide-excision repair
EBA04_08440	COG3723	Recombinational DNA repair protein, rece pathway
EBA04_08530	COG0270	DNA (cytosine-5-)-methyltransferase activity
EBA04_08740	COG3723	Recombinational DNA repair protein, rece pathway
EBA04_08905	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EBA04_08915	COG2986	histidine ammonia-lyase
EBA04_08965	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EBA04_08970	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EBA04_08975	COG0077	Prephenate dehydratase
EBA04_08975	COG1605	Chorismate mutase
EBA04_09005	COG3039	Transposase
EBA04_09015	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EBA04_09030	COG0583	DNA-binding transcription factor activity
EBA04_09045	COG2336	PFAM SpoVT AbrB
EBA04_09085	COG0840	transmembrane signaling receptor activity
EBA04_09110	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
EBA04_09115	COG0784	Response regulator, receiver
EBA04_09115	COG4191	Histidine kinase
EBA04_09130	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EBA04_09150	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EBA04_09165	COG1595	DNA-templated transcription, initiation
EBA04_09215	COG2244	polysaccharide biosynthetic process
EBA04_09245	COG2264	protein methyltransferase activity
EBA04_09255	COG0438	transferase activity, transferring glycosyl groups
EBA04_09270	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
EBA04_09275	COG1132	(ABC) transporter
EBA04_09285	COG0477	Major facilitator Superfamily
EBA04_09305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EBA04_09320	COG1253	flavin adenine dinucleotide binding
EBA04_09335	COG0306	phosphate transporter
EBA04_09375	COG0148	phosphopyruvate hydratase activity
EBA04_09380	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EBA04_09405	COG2840	Smr protein MutS2
EBA04_09420	COG1238	metal cluster binding
EBA04_09435	COG1534	Rna-binding protein
EBA04_09445	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EBA04_09450	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EBA04_09460	COG1923	regulation of RNA biosynthetic process
EBA04_09465	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EBA04_09470	COG1546	Belongs to the CinA family
EBA04_09495	COG2137	regulation of response to DNA damage stimulus
EBA04_09505	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EBA04_09560	COG1741	Belongs to the pirin family
EBA04_09565	COG0583	DNA-binding transcription factor activity
EBA04_09590	COG0351	phosphomethylpyrimidine kinase
EBA04_09590	COG0352	thiamine-phosphate diphosphorylase activity
EBA04_09600	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EBA04_09605	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EBA04_09620	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EBA04_09630	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EBA04_09635	COG3734	2-keto-3-deoxy-galactonokinase
EBA04_09650	COG0800	Aldolase
EBA04_09675	COG1070	Carbohydrate kinase
EBA04_09685	COG0477	Major facilitator Superfamily
EBA04_09705	COG0860	N-Acetylmuramoyl-L-alanine amidase
EBA04_09720	COG0617	tRNA 3'-terminal CCA addition
EBA04_09740	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EBA04_09770	COG1472	Belongs to the glycosyl hydrolase 3 family
EBA04_09790	COG2203	Gaf domain
EBA04_09790	COG3706	GGDEF domain
EBA04_09790	COG5001	Diguanylate cyclase
EBA04_09790	COG4251	negative regulation of phosphorylation
EBA04_09800	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA04_09810	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
EBA04_09825	COG0671	phosphoesterase, PA-phosphatase related
EBA04_09845	COG1794	racemase activity, acting on amino acids and derivatives
EBA04_09855	COG0697	spore germination
EBA04_09860	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EBA04_09885	COG1012	belongs to the aldehyde dehydrogenase family
EBA04_09945	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EBA04_09960	COG0124	histidyl-tRNA synthetase
EBA04_10015	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EBA04_10015	COG0140	phosphoribosyl-ATP diphosphatase activity
EBA04_10045	COG0235	Class ii aldolase
EBA04_10050	COG0531	amino acid
EBA04_10055	COG0531	amino acid
EBA04_10065	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EBA04_10070	COG0277	FAD linked oxidase domain protein
EBA04_10150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EBA04_10155	COG2258	MOSC domain
EBA04_10160	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EBA04_10165	COG0505	Belongs to the CarA family
EBA04_10175	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EBA04_10180	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EBA04_10190	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EBA04_10205	COG3279	Response regulator of the LytR AlgR family
EBA04_10230	COG2205	protein histidine kinase activity
EBA04_10230	COG2198	Histidine kinase
EBA04_10230	COG0784	Response regulator, receiver
EBA04_10235	COG1024	Enoyl-CoA hydratase
EBA04_10240	COG0318	PFAM AMP-dependent synthetase and ligase
EBA04_10270	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EBA04_10300	COG0840	transmembrane signaling receptor activity
EBA04_10310	COG0835	chemotaxis
EBA04_10325	COG0840	transmembrane signaling receptor activity
EBA04_10330	COG0840	transmembrane signaling receptor activity
EBA04_10335	COG0840	transmembrane signaling receptor activity
EBA04_10350	COG0840	transmembrane signaling receptor activity
EBA04_10360	COG0840	transmembrane signaling receptor activity
EBA04_10365	COG0840	transmembrane signaling receptor activity
EBA04_10395	COG0840	transmembrane signaling receptor activity
EBA04_10400	COG2826	transposase and inactivated derivatives, IS30 family
EBA04_10420	COG0745	RESPONSE REGULATOR receiver
EBA04_10430	COG0835	chemotaxis
EBA04_10435	COG1192	Involved in chromosome partitioning
EBA04_10440	COG1360	Flagellar Motor Protein
EBA04_10445	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EBA04_10465	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EBA04_10505	COG3039	Transposase
EBA04_10570	COG2198	Histidine kinase
EBA04_10570	COG0643	Histidine kinase
EBA04_10590	COG0455	bacterial-type flagellum organization
EBA04_10615	COG5001	Diguanylate cyclase
EBA04_10615	COG3300	MHYT domain
EBA04_10620	COG3300	MHYT domain
EBA04_10620	COG5001	Diguanylate cyclase
EBA04_10625	COG1684	flagellar biosynthetic protein fliR
EBA04_10630	COG1987	bacterial-type flagellum assembly
EBA04_10640	COG3190	flagellar
EBA04_10690	COG1677	Flagellar hook-basal body complex protein FliE
EBA04_10725	COG1028	Short-chain dehydrogenase reductase Sdr
EBA04_10735	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EBA04_10750	COG2204	response regulator
EBA04_10755	COG2201	protein-glutamate methylesterase activity
EBA04_10785	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EBA04_10790	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EBA04_10805	COG3951	Flagellar rod assembly protein muramidase FlgJ
EBA04_10805	COG1705	Flagellar rod assembly protein muramidase FlgJ
EBA04_10810	COG1706	bacterial-type flagellum-dependent cell motility
EBA04_10815	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EBA04_10820	COG4786	Flagellar basal body rod
EBA04_10830	COG4787	bacterial-type flagellum-dependent cell motility
EBA04_10835	COG1749	Flagellar hook protein flgE
EBA04_10840	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EBA04_10845	COG1558	bacterial-type flagellum-dependent cell motility
EBA04_10855	COG0784	Response regulator, receiver
EBA04_10855	COG0835	chemotaxis
EBA04_10875	COG5002	protein histidine kinase activity
EBA04_10885	COG4585	Histidine kinase
EBA04_10920	COG0482	sulfurtransferase activity
EBA04_10930	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EBA04_10935	COG0542	response to heat
EBA04_10940	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EBA04_10960	COG0492	ferredoxin-NADP+ reductase activity
EBA04_10965	COG1674	ftsk spoiiie
EBA04_10990	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EBA04_11010	COG0038	chloride channel
EBA04_11015	COG0183	Belongs to the thiolase family
EBA04_11020	COG1024	Enoyl-CoA hydratase
EBA04_11020	COG1250	3-hydroxyacyl-CoA dehydrogenase
EBA04_11030	COG0105	UTP biosynthetic process
EBA04_11055	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EBA04_11060	COG1160	GTP binding
EBA04_11065	COG0303	'Molybdopterin
EBA04_11075	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EBA04_11085	COG2826	transposase and inactivated derivatives, IS30 family
EBA04_11110	COG0746	molybdenum cofactor guanylyltransferase activity
EBA04_11135	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EBA04_11135	COG1648	precorrin-2 dehydrogenase activity
EBA04_11175	COG3039	Transposase
EBA04_11200	COG5001	Diguanylate cyclase
EBA04_11220	COG4566	intracellular signal transduction
EBA04_11260	COG3501	Rhs element vgr protein
EBA04_11345	COG1024	Enoyl-CoA hydratase
EBA04_11350	COG1024	Enoyl-CoA hydratase
EBA04_11360	COG1024	Enoyl-CoA hydratase
EBA04_11375	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EBA04_11485	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EBA04_11490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EBA04_11550	COG1858	cytochrome C peroxidase
EBA04_11580	COG0515	serine threonine protein kinase
EBA04_11585	COG0631	protein serine/threonine phosphatase activity
EBA04_11620	COG3501	Rhs element vgr protein
EBA04_11645	COG2826	transposase and inactivated derivatives, IS30 family
EBA04_11660	COG3039	Transposase
EBA04_11745	COG3039	Transposase
EBA04_11760	COG2154	pterin-4-alpha-carbinolamine dehydratase
EBA04_11775	COG3064	Membrane
EBA04_11785	COG1530	ribonuclease E activity
EBA04_11820	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EBA04_11870	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EBA04_11890	COG0848	biopolymer transport protein
EBA04_11895	COG0811	peptide transport
EBA04_11920	COG4591	ABC-type transport system involved in lipoprotein release permease component
EBA04_11935	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EBA04_11950	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EBA04_11965	COG0354	folic acid binding
EBA04_11980	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EBA04_11990	COG0363	glucosamine-6-phosphate deaminase activity
EBA04_11995	COG0129	dihydroxy-acid dehydratase activity
EBA04_12000	COG0800	Aldolase
EBA04_12080	COG2205	protein histidine kinase activity
EBA04_12080	COG0784	Response regulator, receiver
EBA04_12095	COG2183	response to ionizing radiation
EBA04_12105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA04_12105	COG0723	plastoquinol--plastocyanin reductase activity
EBA04_12120	COG3243	poly(R)-hydroxyalkanoic acid synthase
EBA04_12130	COG1183	phosphatidylcholine synthase activity
EBA04_12135	COG1028	Short-chain dehydrogenase reductase Sdr
EBA04_12150	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EBA04_12160	COG0668	transmembrane transport
EBA04_12170	COG0590	tRNA wobble adenosine to inosine editing
EBA04_12175	COG1321	iron dependent repressor
EBA04_12180	COG1914	H( )-stimulated, divalent metal cation uptake system
EBA04_12210	COG0583	DNA-binding transcription factor activity
EBA04_12235	COG0583	DNA-binding transcription factor activity
EBA04_12240	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EBA04_12250	COG0519	Catalyzes the synthesis of GMP from XMP
EBA04_12250	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EBA04_12275	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EBA04_12285	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EBA04_12290	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EBA04_12305	COG0539	negative regulation of cytoplasmic translation
EBA04_12310	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EBA04_12315	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EBA04_12325	COG2957	Belongs to the agmatine deiminase family
EBA04_12335	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EBA04_12360	COG0395	ABC-type sugar transport system, permease component
EBA04_12365	COG1175	transmembrane transport
EBA04_12395	COG2350	Protein conserved in bacteria
EBA04_12400	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EBA04_12405	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EBA04_12410	COG1187	pseudouridine synthase activity
EBA04_12430	COG0436	Aminotransferase
EBA04_12435	COG4133	protoheme IX ABC transporter activity
EBA04_12485	COG1278	Cold shock
EBA04_12495	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EBA04_12500	COG4988	ABC transporter
EBA04_12510	COG1271	oxidase subunit
EBA04_12580	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EBA04_12585	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EBA04_12590	COG0137	argininosuccinate synthase activity
EBA04_12595	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EBA04_12610	COG2166	iron-sulfur cluster assembly
EBA04_12625	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EBA04_12635	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EBA04_12650	COG4302	ethanolamine ammonia-lyase activity
EBA04_12665	COG4677	pectinesterase activity
EBA04_12700	COG0402	S-adenosylhomocysteine deaminase activity
EBA04_12720	COG1509	lysine 2,3-aminomutase activity
EBA04_12725	COG5001	Diguanylate cyclase
EBA04_12725	COG3300	MHYT domain
EBA04_12740	COG0483	inositol monophosphate 1-phosphatase activity
EBA04_12775	COG0513	Belongs to the DEAD box helicase family
EBA04_12785	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EBA04_12795	COG0625	glutathione transferase activity
EBA04_12810	COG4681	YaeQ
EBA04_12815	COG2081	HI0933 family
EBA04_12820	COG1716	ATPase activity
EBA04_12820	COG5001	Diguanylate cyclase
EBA04_12825	COG0501	Belongs to the peptidase M48B family
EBA04_12835	COG1028	Short-chain dehydrogenase reductase Sdr
EBA04_12860	COG0860	N-Acetylmuramoyl-L-alanine amidase
EBA04_12865	COG0802	atpase or kinase
EBA04_12870	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EBA04_12870	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EBA04_12875	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EBA04_12895	COG3039	Transposase
EBA04_12905	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EBA04_12955	COG0835	chemotaxis
EBA04_12960	COG0840	transmembrane signaling receptor activity
EBA04_12990	COG2969	positive regulation of protein catabolic process
EBA04_12995	COG0625	glutathione transferase activity
EBA04_13000	COG2857	Cytochrome c1
EBA04_13005	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EBA04_13010	COG0723	plastoquinol--plastocyanin reductase activity
EBA04_13020	COG0741	lytic transglycosylase activity
EBA04_13045	COG1702	phosphate starvation-inducible protein PhoH
EBA04_13065	COG4535	Mg2 and Co2 transporter CorC
EBA04_13080	COG1012	belongs to the aldehyde dehydrogenase family
EBA04_13085	COG1177	transmembrane transport
EBA04_13090	COG1176	ABC-type spermidine putrescine transport system, permease component I
EBA04_13100	COG3842	ATPase activity
EBA04_13130	COG3039	Transposase
EBA04_13155	COG0174	glutamine synthetase
EBA04_13160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA04_13165	COG3706	GGDEF domain
EBA04_13165	COG0745	RESPONSE REGULATOR receiver
EBA04_13170	COG0477	Major facilitator Superfamily
EBA04_13180	COG0243	molybdopterin cofactor binding
EBA04_13205	COG1121	(ABC) transporter
EBA04_13215	COG2733	membrane
EBA04_13230	COG3039	Transposase
EBA04_13280	COG3039	Transposase
EBA04_13290	COG2902	Dehydrogenase
EBA04_13300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EBA04_13305	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EBA04_13320	COG1609	Transcriptional regulator
EBA04_13325	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EBA04_13325	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EBA04_13330	COG1105	Belongs to the carbohydrate kinase PfkB family
EBA04_13335	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EBA04_13335	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EBA04_13345	COG3501	Rhs element vgr protein
EBA04_13385	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EBA04_13395	COG1862	Preprotein translocase
EBA04_13465	COG0405	Gamma-glutamyltransferase
EBA04_13470	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EBA04_13490	COG0742	ribosomal rna small subunit methyltransferase
EBA04_13495	COG0326	Molecular chaperone. Has ATPase activity
EBA04_13540	COG4206	TonB-dependent receptor
EBA04_13595	COG3039	Transposase
EBA04_13600	COG3039	Transposase
EBA04_13610	COG0531	amino acid
EBA04_13625	COG0006	proline dipeptidase activity
EBA04_13635	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EBA04_13650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA04_13655	COG3938	Belongs to the proline racemase family
EBA04_13665	COG0552	protein localization to endoplasmic reticulum
EBA04_13680	COG1194	a g-specific adenine glycosylase
EBA04_13690	COG4191	Histidine kinase
EBA04_13690	COG0784	Response regulator, receiver
EBA04_13695	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EBA04_13720	COG3040	lipid binding
EBA04_13730	COG1960	acyl-CoA dehydrogenase activity
EBA04_13780	COG0438	transferase activity, transferring glycosyl groups
EBA04_13785	COG0438	transferase activity, transferring glycosyl groups
EBA04_13830	COG0776	regulation of translation
EBA04_13840	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EBA04_13845	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EBA04_13850	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EBA04_13855	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EBA04_13895	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EBA04_13900	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EBA04_13905	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EBA04_13910	COG3115	cell septum assembly
EBA04_13935	COG0316	Belongs to the HesB IscA family
EBA04_13970	COG0288	reversible hydration of carbon dioxide
EBA04_13995	COG3844	kynureninase activity
EBA04_14005	COG2925	Exonuclease
EBA04_14015	COG0667	Aldo Keto reductase
EBA04_14030	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EBA04_14090	COG0494	nUDIX hydrolase
EBA04_14100	COG1024	Enoyl-CoA hydratase
EBA04_14110	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EBA04_14115	COG0659	secondary active sulfate transmembrane transporter activity
EBA04_14140	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EBA04_14145	COG0573	inorganic phosphate transmembrane transporter activity
EBA04_14150	COG0581	inorganic phosphate transmembrane transporter activity
EBA04_14160	COG0704	Plays a role in the regulation of phosphate uptake
EBA04_14170	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EBA04_14180	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EBA04_14195	COG0557	exoribonuclease II activity
EBA04_14225	COG1960	acyl-CoA dehydrogenase activity
EBA04_14235	COG1410	methionine synthase
EBA04_14235	COG0646	methionine synthase
EBA04_14240	COG0646	methionine synthase
EBA04_14240	COG1410	methionine synthase
EBA04_14250	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBA04_14290	COG0386	Belongs to the glutathione peroxidase family
EBA04_14300	COG1725	Transcriptional regulator
EBA04_14305	COG1131	(ABC) transporter
EBA04_14345	COG3039	Transposase
EBA04_14375	COG2850	peptidyl-arginine hydroxylation
EBA04_14410	COG1132	(ABC) transporter
EBA04_14440	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EBA04_14455	COG0443	Heat shock 70 kDa protein
EBA04_14470	COG0497	DNA recombination
EBA04_14480	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EBA04_14490	COG2914	Belongs to the UPF0125 (RnfH) family
EBA04_14500	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EBA04_14525	COG3039	Transposase
EBA04_14580	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EBA04_14590	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EBA04_14595	COG0174	glutamine synthetase
EBA04_14625	COG3706	GGDEF domain
EBA04_14660	COG0415	Belongs to the DNA photolyase family
EBA04_14665	COG0305	Participates in initiation and elongation during chromosome replication
EBA04_14675	COG0367	asparagine synthase
EBA04_14705	COG0084	hydrolase, TatD family'
EBA04_14710	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EBA04_14750	COG0840	transmembrane signaling receptor activity
EBA04_14765	COG3039	Transposase
EBA04_14780	COG3039	Transposase
EBA04_14815	COG0386	Belongs to the glutathione peroxidase family
EBA04_14915	COG2814	Major facilitator Superfamily
EBA04_14920	COG1566	PFAM secretion protein HlyD family protein
EBA04_14935	COG2207	Transcriptional regulator
EBA04_14965	COG4774	siderophore transport
EBA04_14975	COG0367	asparagine synthase
EBA04_14980	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EBA04_14990	COG1393	Belongs to the ArsC family
EBA04_15010	COG0024	Methionine aminopeptidase
EBA04_15075	COG0575	Belongs to the CDS family
EBA04_15080	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EBA04_15085	COG0750	zinc metalloprotease
EBA04_15100	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EBA04_15130	COG0825	malonyl-CoA metabolic process
EBA04_15205	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EBA04_15220	COG2040	homocysteine
EBA04_15225	COG0833	amino acid
EBA04_15230	COG0346	lactoylglutathione lyase activity
EBA04_15250	COG2878	Part of a membrane complex involved in electron transport
EBA04_15270	COG1595	DNA-templated transcription, initiation
EBA04_15295	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EBA04_15310	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EBA04_15315	COG0251	oxidation-reduction process
EBA04_15325	COG0392	lysyltransferase activity
EBA04_15325	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EBA04_15365	COG2814	Major facilitator Superfamily
EBA04_15370	COG1902	pentaerythritol trinitrate reductase activity
EBA04_15385	COG2824	Alkylphosphonate utilization operon protein PhnA
EBA04_15395	COG1047	Peptidyl-prolyl cis-trans
EBA04_15440	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EBA04_15455	COG1451	nucleotide metabolic process
EBA04_15475	COG0183	Belongs to the thiolase family
EBA04_15490	COG3706	GGDEF domain
EBA04_15490	COG0745	RESPONSE REGULATOR receiver
EBA04_15505	COG1793	dna ligase
EBA04_15505	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EBA04_15515	COG1793	dna ligase
EBA04_15520	COG1201	RNA secondary structure unwinding
EBA04_15540	COG1278	Cold shock
EBA04_15545	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EBA04_15560	COG3046	protein related to deoxyribodipyrimidine photolyase
EBA04_15565	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
EBA04_15620	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EBA04_15635	COG1250	3-hydroxyacyl-CoA dehydrogenase
EBA04_15635	COG1024	Enoyl-CoA hydratase
EBA04_15655	COG1024	Enoyl-CoA hydratase
EBA04_15660	COG1960	acyl-CoA dehydrogenase activity
EBA04_15735	COG2353	YceI-like domain
EBA04_15760	COG1760	l-serine dehydratase
EBA04_15770	COG0626	cystathionine gamma-synthase activity
EBA04_15775	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EBA04_15780	COG0739	heme binding
EBA04_15790	COG1272	protein, Hemolysin III
EBA04_15810	COG0517	IMP dehydrogenase activity
EBA04_15810	COG0516	GMP reductase activity
EBA04_15815	COG0463	Glycosyl transferase, family 2
EBA04_15825	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EBA04_15835	COG4771	TonB-dependent receptor
EBA04_15840	COG1309	transcriptional regulator
EBA04_15850	COG1960	acyl-CoA dehydrogenase activity
EBA04_15895	COG0330	HflC and HflK could
EBA04_15905	COG1742	UPF0060 membrane protein
EBA04_15910	COG3956	TIGRFAM MazG family protein
EBA04_15920	COG0494	nUDIX hydrolase
EBA04_15930	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EBA04_15935	COG0837	glucose binding
EBA04_15950	COG3858	chitin binding
EBA04_15950	COG1388	LysM domain
EBA04_15970	COG1472	Belongs to the glycosyl hydrolase 3 family
EBA04_15995	COG2801	Transposase and inactivated derivatives
EBA04_16005	COG2826	transposase and inactivated derivatives, IS30 family
EBA04_16020	COG3039	Transposase
EBA04_16075	COG3537	Alpha-1,2-mannosidase
EBA04_16120	COG3142	Participates in the control of copper homeostasis
EBA04_16125	COG1446	asparaginase
EBA04_16135	COG2304	oxidoreductase activity
EBA04_16165	COG0840	transmembrane signaling receptor activity
EBA04_16170	COG0835	chemotaxis
EBA04_16185	COG0189	ligase activity
EBA04_16195	COG1397	ADP-ribosylglycohydrolase
EBA04_16205	COG1199	ATP-dependent helicase activity
EBA04_16215	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EBA04_16230	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EBA04_16280	COG1643	Atp-dependent helicase
EBA04_16285	COG0783	Belongs to the Dps family
EBA04_16300	COG0514	ATP-dependent DNA helicase (RecQ)
EBA04_16315	COG3039	Transposase
EBA04_16330	COG1187	pseudouridine synthase activity
EBA04_16380	COG0602	queuosine metabolic process
EBA04_16390	COG2885	chlorophyll binding
EBA04_16395	COG0823	Involved in the tonB-independent uptake of proteins
EBA04_16405	COG0848	biopolymer transport protein
EBA04_16415	COG0824	Thioesterase
EBA04_16435	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EBA04_16455	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EBA04_16470	COG0477	Major facilitator Superfamily
EBA04_16505	COG0488	(ABC) transporter
EBA04_16535	COG4651	solute:proton antiporter activity
EBA04_16535	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EBA04_16565	COG0640	Transcriptional regulator
EBA04_16580	COG4772	TonB-dependent receptor
EBA04_16590	COG4264	IucA IucC family
EBA04_16595	COG2814	Major facilitator Superfamily
EBA04_16605	COG0019	diaminopimelate decarboxylase activity
EBA04_16660	COG4206	TonB-dependent receptor
EBA04_16695	COG0542	response to heat
EBA04_16720	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EBA04_16730	COG0534	Mate efflux family protein
EBA04_16780	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EBA04_16790	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EBA04_16830	COG2172	sigma factor antagonist activity
EBA04_16835	COG1366	Belongs to the anti-sigma-factor antagonist family
EBA04_16840	COG1366	Belongs to the anti-sigma-factor antagonist family
EBA04_16850	COG0326	Molecular chaperone. Has ATPase activity
EBA04_16855	COG2207	Transcriptional regulator
EBA04_16910	COG3209	COG3209 Rhs family protein
EBA04_16920	COG3209	COG3209 Rhs family protein
EBA04_16930	COG3501	Rhs element vgr protein
EBA04_16940	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EBA04_16945	COG1845	cytochrome c oxidase, subunit III
EBA04_16950	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EBA04_16970	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EBA04_16985	COG0728	peptidoglycan biosynthetic process
EBA04_16990	COG0268	Binds directly to 16S ribosomal RNA
EBA04_17010	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EBA04_17015	COG0824	Thioesterase
EBA04_17030	COG1946	Acyl-CoA thioesterase
EBA04_17040	COG1595	DNA-templated transcription, initiation
EBA04_17095	COG1877	trehalose-phosphatase activity
EBA04_17100	COG3387	PFAM Glycoside hydrolase 15-related
EBA04_17135	COG0564	pseudouridine synthase activity
EBA04_17140	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EBA04_17145	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EBA04_17145	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EBA04_17160	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EBA04_17205	COG2194	sulfuric ester hydrolase activity
EBA04_17210	COG4969	Belongs to the N-Me-Phe pilin family
EBA04_17220	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EBA04_17225	COG0237	dephospho-CoA kinase activity
EBA04_17230	COG2205	protein histidine kinase activity
EBA04_17235	COG0745	RESPONSE REGULATOR receiver
EBA04_17255	COG3039	Transposase
EBA04_17270	COG3039	Transposase
EBA04_17285	COG2801	Transposase and inactivated derivatives
EBA04_17295	COG3039	Transposase
EBA04_17335	COG0471	metal ion transport
EBA04_17335	COG3273	potassium ion transport
EBA04_17365	COG1970	mechanosensitive ion channel activity
EBA04_17400	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EBA04_17410	COG0308	aminopeptidase N
EBA04_17415	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EBA04_17425	COG2895	sulfate adenylyltransferase (ATP) activity
EBA04_17425	COG0529	Catalyzes the synthesis of activated sulfate
EBA04_17435	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EBA04_17465	COG0784	Response regulator, receiver
EBA04_17465	COG2198	Histidine kinase
EBA04_17465	COG2205	protein histidine kinase activity
EBA04_17505	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EBA04_17510	COG3588	fructose-bisphosphate aldolase
EBA04_17520	COG0469	pyruvate kinase activity
EBA04_17545	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EBA04_17560	COG3453	Protein conserved in bacteria
EBA04_17560	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EBA04_17565	COG0725	ABC transporter, periplasmic molybdate-binding protein
EBA04_17570	COG4149	molybdate abc transporter
EBA04_17575	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EBA04_17595	COG0642	Histidine kinase
EBA04_17600	COG0745	RESPONSE REGULATOR receiver
EBA04_17610	COG1028	Short-chain dehydrogenase reductase Sdr
EBA04_17620	COG1022	Amp-dependent synthetase and ligase
EBA04_17645	COG1376	ErfK ybiS ycfS ynhG family protein
EBA04_17650	COG0739	heme binding
EBA04_17665	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EBA04_17670	COG1301	dicarboxylic acid transport
EBA04_17690	COG2304	oxidoreductase activity
EBA04_17710	COG0714	Associated with various cellular activities
EBA04_17745	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EBA04_17770	COG0254	rRNA binding
EBA04_17780	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EBA04_17790	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EBA04_17795	COG1758	RNA polymerase activity
EBA04_17810	COG1561	YicC-like family, N-terminal region
EBA04_17830	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EBA04_17860	COG0006	proline dipeptidase activity
EBA04_17905	COG2912	Transglutaminase-like superfamily
EBA04_17910	COG1773	rubredoxin
EBA04_17915	COG0352	thiamine-phosphate diphosphorylase activity
EBA04_17940	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
EBA04_17980	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EBA04_18005	COG0671	phosphoesterase, PA-phosphatase related
EBA04_18020	COG3781	membrane
EBA04_18030	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EBA04_18045	COG3039	Transposase
EBA04_18060	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
EBA04_18070	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EBA04_18095	COG3710	Transcriptional regulator
EBA04_18140	COG2226	methyltransferase
EBA04_18170	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EBA04_18175	COG1538	Outer membrane efflux protein
EBA04_18180	COG1519	Transferase
EBA04_18185	COG1560	Kdo2-lipid A biosynthetic process
EBA04_18205	COG3039	Transposase
EBA04_18215	COG2826	transposase and inactivated derivatives, IS30 family
EBA04_18280	COG3039	Transposase
EBA04_18295	COG0280	phosphate acetyltransferase
EBA04_18295	COG0281	malic enzyme
EBA04_18315	COG4191	Histidine kinase
EBA04_18330	COG0583	DNA-binding transcription factor activity
EBA04_18350	COG2197	response regulator
EBA04_18360	COG0642	Histidine kinase
EBA04_18380	COG2851	Citrate transporter
EBA04_18385	COG1028	Short-chain dehydrogenase reductase Sdr
EBA04_18395	COG1609	Transcriptional regulator
EBA04_18405	COG2211	Major facilitator Superfamily
EBA04_18435	COG0436	Aminotransferase
EBA04_18455	COG0726	polysaccharide deacetylase
EBA04_18460	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EBA04_18480	COG0402	S-adenosylhomocysteine deaminase activity
EBA04_18530	COG0242	peptide deformylase activity
EBA04_18535	COG3039	Transposase
EBA04_18570	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EBA04_18630	COG2188	Transcriptional regulator
EBA04_18645	COG1450	Type ii and iii secretion system protein
EBA04_18660	COG3166	PFAM Fimbrial assembly family protein
EBA04_18665	COG3156	type II secretion system protein K
EBA04_18670	COG4795	General secretion pathway protein
EBA04_18675	COG2165	general secretion pathway protein
EBA04_18680	COG4970	Tfp pilus assembly protein FimT
EBA04_18685	COG2165	general secretion pathway protein
EBA04_18690	COG1459	type II secretion system
EBA04_18700	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EBA04_18705	COG1404	Belongs to the peptidase S8 family
EBA04_18710	COG5295	Hep Hag repeat protein
EBA04_18720	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EBA04_18720	COG0047	phosphoribosylformylglycinamidine synthase activity
EBA04_18730	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EBA04_18735	COG4974	Belongs to the 'phage' integrase family
EBA04_18750	COG0795	lipopolysaccharide-transporting ATPase activity
EBA04_18785	COG0525	valine-tRNA ligase activity
EBA04_18815	COG2826	transposase and inactivated derivatives, IS30 family
EBA04_18825	COG2826	transposase and inactivated derivatives, IS30 family
EBA04_18850	COG1183	phosphatidylcholine synthase activity
EBA04_18875	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EBA04_18880	COG1127	ABC transporter
EBA04_18885	COG3218	ABC-type transport auxiliary lipoprotein component
EBA04_18885	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EBA04_18930	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EBA04_18935	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
EBA04_18935	COG0662	Cupin 2, conserved barrel domain protein
EBA04_18965	COG2086	electron transfer activity
EBA04_19035	COG0626	cystathionine gamma-synthase activity
EBA04_19065	COG0625	glutathione transferase activity
EBA04_19080	COG0513	Belongs to the DEAD box helicase family
EBA04_19090	COG0720	synthase
EBA04_19105	COG1956	GAF domain-containing protein
EBA04_19115	COG0546	phosphoglycolate phosphatase activity
EBA04_19145	COG0339	signal peptide processing
EBA04_19195	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EBA04_19285	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EBA04_19295	COG0356	it plays a direct role in the translocation of protons across the membrane
EBA04_19315	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EBA04_19325	COG0508	dehydrogenase complex catalyzes the overall conversion of
EBA04_19360	COG2011	ABC-type metal ion transport system permease component
EBA04_19370	COG0697	spore germination
EBA04_19405	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EBA04_19410	COG1187	pseudouridine synthase activity
EBA04_19415	COG2813	Specifically methylates the guanine in position
EBA04_19445	COG2202	Pas domain
EBA04_19445	COG2205	protein histidine kinase activity
EBA04_19470	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA04_19475	COG1522	sequence-specific DNA binding
EBA04_19520	COG0745	RESPONSE REGULATOR receiver
EBA04_19535	COG1404	Belongs to the peptidase S8 family
EBA04_19550	COG0842	Transport permease protein
EBA04_19555	COG1131	(ABC) transporter
EBA04_19560	COG0025	NhaP-type Na H and K H
EBA04_19570	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EBA04_19580	COG1573	uracil-dna glycosylase
EBA04_19590	COG3384	dioxygenase
EBA04_19620	COG3590	peptidase
EBA04_19640	COG0531	amino acid
EBA04_19665	COG3685	Protein conserved in bacteria
EBA04_19670	COG3546	catalase activity
EBA04_19695	COG3039	Transposase
EBA04_19725	COG1271	oxidase subunit
EBA04_19730	COG1294	oxidase, subunit
EBA04_19765	COG1063	alcohol dehydrogenase
EBA04_19870	COG1473	amidohydrolase
EBA04_19875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EBA04_19880	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EBA04_19905	COG5383	Protein conserved in bacteria
EBA04_19955	COG3023	N-Acetylmuramoyl-L-alanine amidase
EBA04_19965	COG4948	Mandelate Racemase Muconate Lactonizing
EBA04_19990	COG0531	amino acid
EBA04_20010	COG4682	membrane
EBA04_20015	COG2133	pyrroloquinoline quinone binding
EBA04_20035	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EBA04_20045	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EBA04_20050	COG1610	YqeY-like protein
EBA04_20070	COG1295	ribonuclease BN
EBA04_20075	COG0358	DNA primase activity
EBA04_20135	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
EBA04_20150	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EBA04_20215	COG0739	heme binding
EBA04_20230	COG2211	Major facilitator Superfamily
EBA04_20235	COG0708	Exodeoxyribonuclease III
EBA04_20250	COG1192	Involved in chromosome partitioning
EBA04_20255	COG1475	DNA binding
EBA04_20270	COG0463	Glycosyl transferase, family 2
EBA04_20295	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EBA04_20320	COG4221	oxidoreductase activity
EBA04_20360	COG1166	arginine decarboxylase activity
EBA04_20410	COG0606	chelatase, subunit chli
EBA04_20435	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EBA04_20455	COG3039	Transposase
EBA04_20515	COG1090	epimerase
EBA04_20525	COG0642	Histidine kinase
EBA04_20540	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EBA04_20575	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EBA04_20585	COG1595	DNA-templated transcription, initiation
EBA04_20590	COG0753	catalase activity
EBA04_20615	COG0697	spore germination
EBA04_20640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EBA04_20645	COG0180	Tryptophanyl-tRNA synthetase
EBA04_20650	COG3237	CsbD-like
EBA04_20705	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EBA04_20705	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EBA04_20715	COG3228	Belongs to the MtfA family
EBA04_20730	COG2205	protein histidine kinase activity
EBA04_20735	COG0745	RESPONSE REGULATOR receiver
EBA04_20745	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EBA04_20800	COG3039	Transposase
EBA04_20805	COG1566	PFAM secretion protein HlyD family protein
EBA04_20820	COG1199	ATP-dependent helicase activity
EBA04_20865	COG0583	DNA-binding transcription factor activity
EBA04_20915	COG0625	glutathione transferase activity
EBA04_20925	COG2826	transposase and inactivated derivatives, IS30 family
EBA04_20955	COG4555	ABC transporter
EBA04_20965	COG1476	TRANSCRIPTIONal
EBA04_20985	COG1230	cation diffusion facilitator family transporter
EBA04_20990	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EBA04_20995	COG1131	(ABC) transporter
EBA04_21000	COG0842	Transport permease protein
EBA04_21010	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EBA04_21045	COG2951	lytic endotransglycosylase activity
EBA04_21060	COG1196	nuclear chromosome segregation
EBA04_21065	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EBA04_21075	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EBA04_21090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EBA04_21090	COG1042	CoA-binding domain protein
EBA04_21090	COG0045	succinate-CoA ligase (ADP-forming) activity
EBA04_21100	COG2239	Acts as a magnesium transporter
EBA04_21125	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EBA04_21130	COG3387	PFAM Glycoside hydrolase 15-related
EBA04_21145	COG3100	YcgL domain-containing protein
EBA04_21150	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EBA04_21160	COG0463	Glycosyl transferase, family 2
EBA04_21170	COG1028	Short-chain dehydrogenase reductase Sdr
EBA04_21200	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EBA04_21215	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EBA04_21335	COG0210	DNA helicase
EBA04_21355	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EBA04_21370	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EBA04_21385	COG2159	amidohydrolase
EBA04_21390	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EBA04_21395	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EBA04_21415	COG0357	Ribosomal RNA small subunit methyltransferase G
EBA04_21420	COG3540	Alkaline phosphatase
EBA04_21430	COG2091	lysine biosynthetic process via aminoadipic acid
EBA04_21445	COG0708	Exodeoxyribonuclease III
EBA04_21460	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EBA04_21465	COG3162	membrane
EBA04_21520	COG1028	Short-chain dehydrogenase reductase Sdr
EBA04_21525	COG0179	Fumarylacetoacetate (FAA) hydrolase
EBA04_21535	COG4948	Mandelate Racemase Muconate Lactonizing
EBA04_21540	COG3254	rhamnose metabolic process
EBA04_21545	COG0738	Major facilitator superfamily
EBA04_21550	COG1414	Transcriptional regulator
EBA04_21560	COG2205	protein histidine kinase activity
EBA04_21570	COG3459	Glycosyltransferase 36 associated
EBA04_21575	COG2211	Major facilitator Superfamily
EBA04_21580	COG3265	gluconokinase activity
EBA04_21585	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EBA04_21615	COG3039	Transposase
EBA04_21625	COG3039	Transposase
EBA04_21630	COG2911	Protein conserved in bacteria
EBA04_21635	COG0729	surface antigen
EBA04_21640	COG4771	TonB-dependent receptor
EBA04_21645	COG0457	Tetratricopeptide repeat
EBA04_21655	COG0752	glycyl-tRNA synthetase alpha subunit
EBA04_21660	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EBA04_21670	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EBA04_21670	COG0519	Catalyzes the synthesis of GMP from XMP
EBA04_21680	COG0805	protein transport
EBA04_21685	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EBA04_21690	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EBA04_21700	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EBA04_21730	COG2974	May be involved in recombination
EBA04_21735	COG0037	tRNA processing
EBA04_21760	COG3661	Belongs to the glycosyl hydrolase 67 family
EBA04_21770	COG4948	Mandelate Racemase Muconate Lactonizing
EBA04_21780	COG1472	Belongs to the glycosyl hydrolase 3 family
EBA04_21785	COG0246	Mannitol dehydrogenase
EBA04_21820	COG2826	transposase and inactivated derivatives, IS30 family
EBA04_21845	COG3693	PFAM glycoside hydrolase, family 10
EBA04_21870	COG2211	Major facilitator Superfamily
EBA04_21885	COG3039	Transposase
EBA04_21920	COG2937	Belongs to the GPAT DAPAT family
EBA04_21960	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EBA04_21980	COG0210	DNA helicase
EBA04_21995	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
EBA04_22060	COG0676	glucose-6-phosphate 1-epimerase activity
EBA04_22075	COG0730	response to heat
EBA04_22110	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EBA04_22115	COG0302	gtp cyclohydrolase
EBA04_22145	COG2826	transposase and inactivated derivatives, IS30 family
EBA04_22155	COG0477	Major facilitator Superfamily
EBA04_22170	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EBA04_22215	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EBA04_22265	COG3237	CsbD-like
EBA04_22285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBA04_22340	COG4772	TonB-dependent receptor
EBA04_22350	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EBA04_22380	COG3039	Transposase
EBA04_22430	COG0564	pseudouridine synthase activity
EBA04_22445	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EBA04_22465	COG3039	Transposase
EBA04_22485	COG3039	Transposase
EBA04_22510	COG3039	Transposase
EBA04_22585	COG1074	ATP-dependent DNA helicase activity
EBA04_22590	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EBA04_22605	COG3039	Transposase
EBA04_22610	COG3039	Transposase
EBA04_22620	COG1136	(ABC) transporter
EBA04_22640	COG1127	ABC transporter
EBA04_22645	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EBA04_22650	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EBA04_22665	COG2853	Lipoprotein
EBA04_22690	COG0386	Belongs to the glutathione peroxidase family
EBA04_22700	COG1322	Protein conserved in bacteria
EBA04_22705	COG3039	Transposase
EBA04_22730	COG1929	Belongs to the glycerate kinase type-1 family
EBA04_22735	COG2271	Major facilitator Superfamily
EBA04_22750	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EBA04_22760	COG0861	Integral membrane protein TerC family
EBA04_22775	COG0584	glycerophosphoryl diester phosphodiesterase
EBA04_22785	COG0671	phosphoesterase, PA-phosphatase related
EBA04_22790	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EBA04_22795	COG0726	polysaccharide deacetylase
EBA04_22810	COG0230	Belongs to the bacterial ribosomal protein bL34 family