locus-tag	class	description
EBA05_00025	COG0187	DNA topoisomerase II activity
EBA05_00035	COG0501	Belongs to the peptidase M48B family
EBA05_00065	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EBA05_00095	COG3039	Transposase
EBA05_00145	COG0793	Belongs to the peptidase S41A family
EBA05_00150	COG4942	peptidase
EBA05_00160	COG2234	aminopeptidase activity
EBA05_00170	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA05_00185	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA05_00195	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA05_00205	COG1064	alcohol dehydrogenase
EBA05_00230	COG0493	'glutamate synthase
EBA05_00235	COG0067	glutamate synthase
EBA05_00235	COG0069	glutamate synthase activity
EBA05_00235	COG0070	glutamate synthase
EBA05_00305	COG1205	dead DEAH box helicase
EBA05_00305	COG1111	helicase
EBA05_00310	COG1272	protein, Hemolysin III
EBA05_00340	COG2032	superoxide dismutase activity
EBA05_00345	COG2204	response regulator
EBA05_00350	COG3852	Histidine kinase
EBA05_00355	COG0004	ammonium transporteR
EBA05_00360	COG0347	Belongs to the P(II) protein family
EBA05_00365	COG0174	glutamine synthetase
EBA05_00420	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EBA05_00430	COG2062	phosphohistidine phosphatase, SixA
EBA05_00435	COG0489	protein tyrosine kinase activity
EBA05_00455	COG1396	sequence-specific DNA binding
EBA05_00460	COG3550	peptidyl-serine autophosphorylation
EBA05_00465	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
EBA05_00470	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EBA05_00485	COG1125	glycine betaine transport
EBA05_00485	COG0517	IMP dehydrogenase activity
EBA05_00500	COG1119	ATPase activity
EBA05_00515	COG1752	Esterase of the alpha-beta hydrolase superfamily
EBA05_00525	COG1522	sequence-specific DNA binding
EBA05_00530	COG3186	Phenylalanine-4-hydroxylase
EBA05_00560	COG1609	Transcriptional regulator
EBA05_00600	COG0366	Alpha amylase catalytic
EBA05_00605	COG0366	Alpha amylase catalytic
EBA05_00615	COG3039	Transposase
EBA05_00625	COG0183	Belongs to the thiolase family
EBA05_00665	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EBA05_00670	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EBA05_00685	COG0028	Belongs to the TPP enzyme family
EBA05_00690	COG4191	Histidine kinase
EBA05_00715	COG3039	Transposase
EBA05_00725	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EBA05_00740	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EBA05_00745	COG3177	Filamentation induced by cAMP protein fic
EBA05_00750	COG0596	Alpha beta hydrolase
EBA05_00765	COG0318	PFAM AMP-dependent synthetase and ligase
EBA05_00770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EBA05_00785	COG1181	Belongs to the D-alanine--D-alanine ligase family
EBA05_00815	COG0564	pseudouridine synthase activity
EBA05_00845	COG0339	signal peptide processing
EBA05_00900	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EBA05_00905	COG1960	acyl-CoA dehydrogenase activity
EBA05_00960	COG0697	spore germination
EBA05_00970	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EBA05_00975	COG1846	Transcriptional regulator
EBA05_00980	COG1764	response to oxidative stress
EBA05_01005	COG3501	Rhs element vgr protein
EBA05_01030	COG0656	L-ascorbic acid biosynthetic process
EBA05_01045	COG2130	NADP-dependent
EBA05_01060	COG1187	pseudouridine synthase activity
EBA05_01075	COG1643	Atp-dependent helicase
EBA05_01085	COG4807	Protein conserved in bacteria
EBA05_01090	COG2072	flavoprotein involved in K transport
EBA05_01110	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EBA05_01115	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EBA05_01155	COG3039	Transposase
EBA05_01200	COG0084	hydrolase, TatD family'
EBA05_01220	COG0583	DNA-binding transcription factor activity
EBA05_01225	COG2814	Major facilitator Superfamily
EBA05_01235	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EBA05_01240	COG1902	pentaerythritol trinitrate reductase activity
EBA05_01270	COG0745	RESPONSE REGULATOR receiver
EBA05_01290	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EBA05_01295	COG0583	DNA-binding transcription factor activity
EBA05_01325	COG0702	epimerase
EBA05_01330	COG1733	regulation of RNA biosynthetic process
EBA05_01365	COG3039	Transposase
EBA05_01385	COG3501	Rhs element vgr protein
EBA05_01410	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EBA05_01480	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EBA05_01485	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EBA05_01495	COG3485	protocatechuate 3,4-dioxygenase
EBA05_01500	COG3485	protocatechuate 3,4-dioxygenase
EBA05_01515	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EBA05_01520	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EBA05_01535	COG1414	Transcriptional regulator
EBA05_01625	COG1040	competence protein
EBA05_01630	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EBA05_01730	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EBA05_01805	COG1511	domain protein
EBA05_01805	COG3264	Mechanosensitive ion channel
EBA05_01815	COG3039	Transposase
EBA05_01820	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EBA05_01830	COG2354	Protein conserved in bacteria
EBA05_01840	COG3706	GGDEF domain
EBA05_01840	COG0745	RESPONSE REGULATOR receiver
EBA05_01855	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EBA05_01880	COG0702	epimerase
EBA05_01890	COG1028	Short-chain dehydrogenase reductase Sdr
EBA05_01935	COG0513	Belongs to the DEAD box helicase family
EBA05_01945	COG3039	Transposase
EBA05_01975	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EBA05_01990	COG3104	oligopeptide transport
EBA05_02020	COG1320	monovalent cation:proton antiporter activity
EBA05_02025	COG2212	antiporter activity
EBA05_02035	COG0651	ATP synthesis coupled electron transport
EBA05_02040	COG1006	Multisubunit Na H antiporter MnhC subunit
EBA05_02045	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EBA05_02045	COG2111	Na H antiporter
EBA05_02080	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EBA05_02090	COG0456	acetyltransferase
EBA05_02135	COG0134	indole-3-glycerol-phosphate synthase activity
EBA05_02145	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EBA05_02190	COG2906	2 iron, 2 sulfur cluster binding
EBA05_02240	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
EBA05_02260	COG2814	Major facilitator Superfamily
EBA05_02270	COG2814	Major facilitator Superfamily
EBA05_02275	COG1289	transmembrane transporter activity
EBA05_02285	COG0151	Belongs to the GarS family
EBA05_02290	COG0138	bifunctional purine biosynthesis protein purh
EBA05_02295	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EBA05_02305	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EBA05_02360	COG0439	Biotin carboxylase
EBA05_02370	COG0511	ligase activity, forming carbon-carbon bonds
EBA05_02390	COG1324	tolerance protein
EBA05_02410	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EBA05_02430	COG0534	Mate efflux family protein
EBA05_02435	COG0616	signal peptide processing
EBA05_02445	COG1028	Short-chain dehydrogenase reductase Sdr
EBA05_02465	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EBA05_02465	COG1754	DNA topoisomerase type I activity
EBA05_02485	COG0758	DNA mediated transformation
EBA05_02490	COG1652	LysM domain
EBA05_02495	COG0242	peptide deformylase activity
EBA05_02505	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EBA05_02505	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EBA05_02555	COG1560	Kdo2-lipid A biosynthetic process
EBA05_02565	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EBA05_02595	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EBA05_02600	COG3118	belongs to the thioredoxin family
EBA05_02610	COG2884	Cell division ATP-binding protein ftsE
EBA05_02615	COG2177	Part of the ABC transporter FtsEX involved in
EBA05_02620	COG3437	response regulator, receiver
EBA05_02630	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EBA05_02635	COG2860	membrane
EBA05_02640	COG1252	NADH dehydrogenase
EBA05_02660	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EBA05_02680	COG3039	Transposase
EBA05_02695	COG3039	Transposase
EBA05_02705	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EBA05_02720	COG3386	PFAM SMP-30 Gluconolaconase
EBA05_02735	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EBA05_02780	COG2353	YceI-like domain
EBA05_02835	COG3501	Rhs element vgr protein
EBA05_02895	COG4221	oxidoreductase activity
EBA05_02950	COG0697	spore germination
EBA05_02955	COG4305	rare lipoprotein A
EBA05_02960	COG5297	Belongs to the glycosyl hydrolase family 6
EBA05_02970	COG1113	amino acid transport
EBA05_02980	COG0598	Magnesium transport protein CorA
EBA05_03060	COG3300	MHYT domain
EBA05_03060	COG5001	Diguanylate cyclase
EBA05_03085	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA05_03085	COG5297	Belongs to the glycosyl hydrolase family 6
EBA05_03090	COG0659	secondary active sulfate transmembrane transporter activity
EBA05_03095	COG3706	GGDEF domain
EBA05_03125	COG3275	phosphorelay sensor kinase activity
EBA05_03160	COG1505	serine-type exopeptidase activity
EBA05_03180	COG2832	Protein of unknown function (DUF454)
EBA05_03200	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EBA05_03210	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EBA05_03245	COG3300	MHYT domain
EBA05_03245	COG5001	Diguanylate cyclase
EBA05_03250	COG0308	aminopeptidase N
EBA05_03270	COG1077	Cell shape determining protein MreB Mrl
EBA05_03275	COG1792	Involved in formation and maintenance of cell shape
EBA05_03290	COG0772	Belongs to the SEDS family
EBA05_03315	COG2951	lytic endotransglycosylase activity
EBA05_03320	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EBA05_03325	COG1686	Belongs to the peptidase S11 family
EBA05_03365	COG1051	belongs to the nudix hydrolase family
EBA05_03365	COG1056	cytidyltransferase-related domain
EBA05_03400	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EBA05_03405	COG0673	inositol 2-dehydrogenase activity
EBA05_03410	COG2823	Periplasmic or secreted lipoprotein
EBA05_03415	COG4251	negative regulation of phosphorylation
EBA05_03420	COG0784	Response regulator, receiver
EBA05_03425	COG4191	Histidine kinase
EBA05_03430	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EBA05_03455	COG3039	Transposase
EBA05_03475	COG3250	beta-galactosidase activity
EBA05_03500	COG1609	Transcriptional regulator
EBA05_03505	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EBA05_03510	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EBA05_03525	COG1215	transferase activity, transferring glycosyl groups
EBA05_03530	COG0726	polysaccharide deacetylase
EBA05_03530	COG1649	PFAM Uncharacterised BCR, COG1649
EBA05_03550	COG3039	Transposase
EBA05_03635	COG2205	protein histidine kinase activity
EBA05_03640	COG0745	RESPONSE REGULATOR receiver
EBA05_03665	COG3791	Glutathione-dependent formaldehyde-activating
EBA05_03680	COG3039	Transposase
EBA05_03695	COG0488	(ABC) transporter
EBA05_03725	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EBA05_03735	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EBA05_03735	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EBA05_03765	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EBA05_03790	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EBA05_03795	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EBA05_03805	COG2205	protein histidine kinase activity
EBA05_03810	COG0745	RESPONSE REGULATOR receiver
EBA05_03840	COG0277	FAD linked oxidase domain protein
EBA05_03895	COG3116	cell division
EBA05_03910	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EBA05_03915	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EBA05_03935	COG1181	Belongs to the D-alanine--D-alanine ligase family
EBA05_03940	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EBA05_03965	COG0741	lytic transglycosylase activity
EBA05_03965	COG0739	heme binding
EBA05_03965	COG1196	nuclear chromosome segregation
EBA05_03980	COG0494	nUDIX hydrolase
EBA05_03995	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EBA05_04010	COG3321	synthase
EBA05_04010	COG0604	alcohol dehydrogenase
EBA05_04010	COG1028	Short-chain dehydrogenase reductase Sdr
EBA05_04070	COG2226	methyltransferase
EBA05_04100	COG2826	transposase and inactivated derivatives, IS30 family
EBA05_04125	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EBA05_04140	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EBA05_04150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBA05_04155	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EBA05_04165	COG0667	Aldo Keto reductase
EBA05_04195	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EBA05_04205	COG2175	clavaminate synthase activity
EBA05_04215	COG4181	ATPase activity
EBA05_04230	COG0642	Histidine kinase
EBA05_04245	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EBA05_04285	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EBA05_04310	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EBA05_04325	COG0123	including yeast histone deacetylase and acetoin utilization protein
EBA05_04330	COG2096	Adenosyltransferase
EBA05_04345	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EBA05_04350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EBA05_04370	COG1802	Transcriptional regulator
EBA05_04380	COG3384	dioxygenase
EBA05_04385	COG0583	DNA-binding transcription factor activity
EBA05_04390	COG0318	PFAM AMP-dependent synthetase and ligase
EBA05_04400	COG1024	Enoyl-CoA hydratase
EBA05_04420	COG3386	PFAM SMP-30 Gluconolaconase
EBA05_04470	COG2197	response regulator
EBA05_04480	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EBA05_04485	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EBA05_04490	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EBA05_04500	COG0583	DNA-binding transcription factor activity
EBA05_04505	COG3634	alkyl hydroperoxide reductase activity
EBA05_04515	COG2890	protein-(glutamine-N5) methyltransferase activity
EBA05_04555	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EBA05_04555	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EBA05_04570	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EBA05_04595	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EBA05_04600	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EBA05_04625	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EBA05_04635	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EBA05_04665	COG1295	ribonuclease BN
EBA05_04670	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EBA05_04675	COG1254	Belongs to the acylphosphatase family
EBA05_04690	COG0521	Mo-molybdopterin cofactor biosynthetic process
EBA05_04705	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EBA05_04730	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EBA05_04745	COG0012	GTP binding
EBA05_04775	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EBA05_04780	COG0250	Participates in transcription elongation, termination and antitermination
EBA05_04795	COG0081	regulation of translation
EBA05_04800	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EBA05_04820	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EBA05_04845	COG0051	transcription antitermination factor activity, RNA binding
EBA05_04860	COG0089	rRNA binding
EBA05_04865	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EBA05_04885	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EBA05_04890	COG0255	Belongs to the universal ribosomal protein uL29 family
EBA05_04895	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EBA05_04905	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EBA05_04915	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EBA05_04935	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EBA05_04940	COG1841	ribosomal large subunit assembly
EBA05_04945	COG0200	Binds to the 23S rRNA
EBA05_04950	COG0201	protein transport
EBA05_04955	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EBA05_04970	COG0202	RNA polymerase activity
EBA05_04975	COG0203	ribosomal protein L17
EBA05_04990	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
EBA05_05015	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EBA05_05025	COG0625	glutathione transferase activity
EBA05_05055	COG3039	Transposase
EBA05_05075	COG1902	pentaerythritol trinitrate reductase activity
EBA05_05075	COG0446	pyridine nucleotide-disulphide oxidoreductase
EBA05_05080	COG0604	alcohol dehydrogenase
EBA05_05110	COG0156	8-amino-7-oxononanoate synthase activity
EBA05_05115	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EBA05_05120	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EBA05_05125	COG4208	sulfate ABC transporter
EBA05_05130	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EBA05_05140	COG1063	alcohol dehydrogenase
EBA05_05165	COG0406	alpha-ribazole phosphatase activity
EBA05_05180	COG0285	dihydrofolate synthase activity
EBA05_05200	COG2833	Protein of unknown function (DUF455)
EBA05_05230	COG0671	phosphoesterase, PA-phosphatase related
EBA05_05245	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EBA05_05250	COG5002	protein histidine kinase activity
EBA05_05260	COG4783	chaperone-mediated protein folding
EBA05_05275	COG0473	3-isopropylmalate dehydrogenase activity
EBA05_05320	COG3039	Transposase
EBA05_05345	COG0544	peptidyl-prolyl cis-trans isomerase activity
EBA05_05350	COG0740	serine-type endopeptidase activity
EBA05_05385	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EBA05_05410	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EBA05_05425	COG0631	protein serine/threonine phosphatase activity
EBA05_05460	COG0859	PFAM glycosyl transferase family 9
EBA05_05470	COG1234	tRNA 3'-trailer cleavage
EBA05_05475	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EBA05_05490	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EBA05_05495	COG0314	molybdopterin synthase activity
EBA05_05530	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EBA05_05540	COG0537	adenosine 5'-monophosphoramidase activity
EBA05_05560	COG0714	Associated with various cellular activities
EBA05_05580	COG1399	metal-binding, possibly nucleic acid-binding protein
EBA05_05605	COG1028	Short-chain dehydrogenase reductase Sdr
EBA05_05620	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EBA05_05625	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EBA05_05660	COG3829	transcription factor binding
EBA05_05700	COG3039	Transposase
EBA05_05775	COG0330	HflC and HflK could
EBA05_05780	COG0330	HflC and HflK could
EBA05_05790	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EBA05_05795	COG0308	aminopeptidase N
EBA05_05810	COG0732	type I restriction modification DNA specificity domain
EBA05_05825	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
EBA05_05865	COG0406	alpha-ribazole phosphatase activity
EBA05_05865	COG0328	RNA-DNA hybrid ribonuclease activity
EBA05_05910	COG0587	DNA-directed DNA polymerase activity
EBA05_05930	COG1297	OPT oligopeptide transporter protein
EBA05_05945	COG0823	Involved in the tonB-independent uptake of proteins
EBA05_05945	COG1506	peptidase
EBA05_05955	COG2207	Transcriptional regulator
EBA05_05955	COG1917	Cupin 2, conserved barrel domain protein
EBA05_06000	COG0753	catalase activity
EBA05_06040	COG3551	Protein conserved in bacteria
EBA05_06070	COG2194	sulfuric ester hydrolase activity
EBA05_06080	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EBA05_06085	COG0745	RESPONSE REGULATOR receiver
EBA05_06090	COG0642	Histidine kinase
EBA05_06100	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EBA05_06105	COG2894	cell division
EBA05_06120	COG4585	Histidine kinase
EBA05_06125	COG2197	response regulator
EBA05_06140	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EBA05_06165	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EBA05_06230	COG3501	Rhs element vgr protein
EBA05_06240	COG2826	transposase and inactivated derivatives, IS30 family
EBA05_06265	COG3039	Transposase
EBA05_06380	COG3501	Rhs element vgr protein
EBA05_06445	COG1842	Phage shock protein A
EBA05_06470	COG0754	glutathionylspermidine amidase activity
EBA05_06550	COG0531	amino acid
EBA05_06555	COG2197	response regulator
EBA05_06570	COG1113	amino acid transport
EBA05_06600	COG3039	Transposase
EBA05_06610	COG1294	oxidase, subunit
EBA05_06620	COG2239	Acts as a magnesium transporter
EBA05_06630	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EBA05_06635	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EBA05_06650	COG3039	Transposase
EBA05_06675	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EBA05_06690	COG1137	ATPase activity
EBA05_06695	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EBA05_06705	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EBA05_06715	COG0271	Belongs to the BolA IbaG family
EBA05_06720	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EBA05_06745	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EBA05_06770	COG0628	permease
EBA05_06780	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EBA05_06785	COG3178	'Phosphotransferase
EBA05_06795	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EBA05_06800	COG1555	photosystem II stabilization
EBA05_06820	COG3039	Transposase
EBA05_06840	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EBA05_06845	COG0719	Fe-S assembly protein
EBA05_06850	COG0396	ATPase activity
EBA05_06855	COG0719	Fe-S assembly protein
EBA05_06860	COG1959	2 iron, 2 sulfur cluster binding
EBA05_06915	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EBA05_06950	COG0519	Catalyzes the synthesis of GMP from XMP
EBA05_06965	COG1678	Uncharacterized ACR, COG1678
EBA05_06975	COG0540	Belongs to the ATCase OTCase family
EBA05_06985	COG1764	response to oxidative stress
EBA05_06995	COG0384	phenazine biosynthesis protein PhzF
EBA05_07005	COG0527	aspartate kinase activity
EBA05_07035	COG3039	Transposase
EBA05_07045	COG0142	geranyltranstransferase activity
EBA05_07050	COG0629	single-stranded DNA binding
EBA05_07055	COG3706	GGDEF domain
EBA05_07055	COG4251	negative regulation of phosphorylation
EBA05_07055	COG2203	Gaf domain
EBA05_07055	COG5001	Diguanylate cyclase
EBA05_07100	COG2879	small protein
EBA05_07105	COG1966	Carbon starvation protein
EBA05_07110	COG1741	Belongs to the pirin family
EBA05_07120	COG3501	Rhs element vgr protein
EBA05_07205	COG1515	deoxyribonuclease V activity
EBA05_07225	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EBA05_07230	COG2200	EAL domain
EBA05_07230	COG2202	Pas domain
EBA05_07230	COG2199	diguanylate cyclase activity
EBA05_07235	COG0835	chemotaxis
EBA05_07240	COG0840	transmembrane signaling receptor activity
EBA05_07250	COG0643	Histidine kinase
EBA05_07250	COG2198	Histidine kinase
EBA05_07260	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EBA05_07270	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EBA05_07310	COG0735	belongs to the Fur family
EBA05_07340	COG2826	transposase and inactivated derivatives, IS30 family
EBA05_07430	COG3039	Transposase
EBA05_07495	COG5002	protein histidine kinase activity
EBA05_07495	COG5001	Diguanylate cyclase
EBA05_07500	COG1187	pseudouridine synthase activity
EBA05_07525	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EBA05_07530	COG0475	glutathione-regulated potassium exporter activity
EBA05_07535	COG5000	phosphorelay sensor kinase activity
EBA05_07535	COG5002	protein histidine kinase activity
EBA05_07540	COG0745	RESPONSE REGULATOR receiver
EBA05_07545	COG1538	Outer membrane efflux protein
EBA05_07570	COG1132	(ABC) transporter
EBA05_07595	COG3039	Transposase
EBA05_07640	COG3118	belongs to the thioredoxin family
EBA05_07670	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EBA05_07690	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EBA05_07715	COG2968	Membrane
EBA05_07725	COG1530	ribonuclease E activity
EBA05_07730	COG3164	Protein of unknown function
EBA05_07740	COG0312	modulator of DNA gyrase
EBA05_07745	COG3028	Belongs to the UPF0307 family
EBA05_07750	COG0312	modulator of DNA gyrase
EBA05_07765	COG4104	PAAR repeat-containing protein
EBA05_07775	COG0142	geranyltranstransferase activity
EBA05_07780	COG1722	exodeoxyribonuclease VII activity
EBA05_07785	COG0037	tRNA processing
EBA05_07795	COG1301	dicarboxylic acid transport
EBA05_07800	COG4106	trans-aconitate 2-methyltransferase activity
EBA05_07810	COG0791	NLP P60 protein
EBA05_07815	COG0791	NLP P60 protein
EBA05_07820	COG1047	Peptidyl-prolyl cis-trans
EBA05_07825	COG2311	Membrane
EBA05_07830	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA05_07860	COG3039	Transposase
EBA05_07870	COG2826	transposase and inactivated derivatives, IS30 family
EBA05_07900	COG2826	transposase and inactivated derivatives, IS30 family
EBA05_07905	COG3039	Transposase
EBA05_07920	COG0489	protein tyrosine kinase activity
EBA05_07930	COG0717	Belongs to the dCTP deaminase family
EBA05_07945	COG3039	Transposase
EBA05_07965	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EBA05_07975	COG3039	Transposase
EBA05_07985	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EBA05_08000	COG2826	transposase and inactivated derivatives, IS30 family
EBA05_08010	COG0433	COG0433 Predicted ATPase
EBA05_08040	COG2890	protein-(glutamine-N5) methyltransferase activity
EBA05_08050	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EBA05_08055	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EBA05_08090	COG0133	tryptophan synthase activity
EBA05_08165	COG1028	Short-chain dehydrogenase reductase Sdr
EBA05_08185	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EBA05_08205	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EBA05_08215	COG1034	ATP synthesis coupled electron transport
EBA05_08220	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EBA05_08225	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EBA05_08235	COG0713	ATP synthesis coupled electron transport
EBA05_08250	COG1007	ATP synthesis coupled electron transport
EBA05_08265	COG0195	Participates in both transcription termination and antitermination
EBA05_08270	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EBA05_08285	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EBA05_08320	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EBA05_08325	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EBA05_08335	COG2095	MarC family integral membrane protein
EBA05_08350	COG3039	Transposase
EBA05_08355	COG1611	Belongs to the LOG family
EBA05_08400	COG4969	Belongs to the N-Me-Phe pilin family
EBA05_08405	COG0556	nucleotide-excision repair
EBA05_08435	COG3723	Recombinational DNA repair protein, rece pathway
EBA05_08525	COG0270	DNA (cytosine-5-)-methyltransferase activity
EBA05_08730	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EBA05_08740	COG2986	histidine ammonia-lyase
EBA05_08790	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EBA05_08795	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EBA05_08800	COG1605	Chorismate mutase
EBA05_08800	COG0077	Prephenate dehydratase
EBA05_08830	COG3039	Transposase
EBA05_08840	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EBA05_08855	COG0583	DNA-binding transcription factor activity
EBA05_08870	COG2336	PFAM SpoVT AbrB
EBA05_08910	COG0840	transmembrane signaling receptor activity
EBA05_08935	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
EBA05_08940	COG0784	Response regulator, receiver
EBA05_08940	COG4191	Histidine kinase
EBA05_08955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EBA05_08975	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EBA05_08990	COG1595	DNA-templated transcription, initiation
EBA05_09040	COG2244	polysaccharide biosynthetic process
EBA05_09070	COG2264	protein methyltransferase activity
EBA05_09080	COG0438	transferase activity, transferring glycosyl groups
EBA05_09095	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
EBA05_09100	COG1132	(ABC) transporter
EBA05_09110	COG0477	Major facilitator Superfamily
EBA05_09130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EBA05_09145	COG1253	flavin adenine dinucleotide binding
EBA05_09160	COG0306	phosphate transporter
EBA05_09200	COG0148	phosphopyruvate hydratase activity
EBA05_09205	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EBA05_09230	COG2840	Smr protein MutS2
EBA05_09245	COG1238	metal cluster binding
EBA05_09260	COG1534	Rna-binding protein
EBA05_09270	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EBA05_09275	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EBA05_09285	COG1923	regulation of RNA biosynthetic process
EBA05_09290	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EBA05_09295	COG1546	Belongs to the CinA family
EBA05_09320	COG2137	regulation of response to DNA damage stimulus
EBA05_09330	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EBA05_09385	COG1741	Belongs to the pirin family
EBA05_09390	COG0583	DNA-binding transcription factor activity
EBA05_09415	COG0352	thiamine-phosphate diphosphorylase activity
EBA05_09415	COG0351	phosphomethylpyrimidine kinase
EBA05_09425	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EBA05_09430	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EBA05_09445	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EBA05_09455	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EBA05_09460	COG3734	2-keto-3-deoxy-galactonokinase
EBA05_09475	COG0800	Aldolase
EBA05_09500	COG1070	Carbohydrate kinase
EBA05_09510	COG0477	Major facilitator Superfamily
EBA05_09530	COG0860	N-Acetylmuramoyl-L-alanine amidase
EBA05_09545	COG0617	tRNA 3'-terminal CCA addition
EBA05_09565	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EBA05_09595	COG1472	Belongs to the glycosyl hydrolase 3 family
EBA05_09615	COG2203	Gaf domain
EBA05_09615	COG5001	Diguanylate cyclase
EBA05_09615	COG3706	GGDEF domain
EBA05_09615	COG4251	negative regulation of phosphorylation
EBA05_09625	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA05_09635	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
EBA05_09650	COG0671	phosphoesterase, PA-phosphatase related
EBA05_09670	COG1794	racemase activity, acting on amino acids and derivatives
EBA05_09680	COG0697	spore germination
EBA05_09685	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EBA05_09710	COG1012	belongs to the aldehyde dehydrogenase family
EBA05_09770	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EBA05_09785	COG0124	histidyl-tRNA synthetase
EBA05_09840	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EBA05_09840	COG0140	phosphoribosyl-ATP diphosphatase activity
EBA05_09870	COG0235	Class ii aldolase
EBA05_09875	COG0531	amino acid
EBA05_09880	COG0531	amino acid
EBA05_09890	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EBA05_09895	COG0277	FAD linked oxidase domain protein
EBA05_09975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EBA05_09980	COG2258	MOSC domain
EBA05_09985	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EBA05_09990	COG0505	Belongs to the CarA family
EBA05_10000	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EBA05_10005	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EBA05_10015	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EBA05_10030	COG3279	Response regulator of the LytR AlgR family
EBA05_10055	COG2205	protein histidine kinase activity
EBA05_10055	COG2198	Histidine kinase
EBA05_10055	COG0784	Response regulator, receiver
EBA05_10060	COG1024	Enoyl-CoA hydratase
EBA05_10065	COG0318	PFAM AMP-dependent synthetase and ligase
EBA05_10095	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EBA05_10125	COG0840	transmembrane signaling receptor activity
EBA05_10135	COG0835	chemotaxis
EBA05_10150	COG0840	transmembrane signaling receptor activity
EBA05_10155	COG0840	transmembrane signaling receptor activity
EBA05_10160	COG0840	transmembrane signaling receptor activity
EBA05_10175	COG0840	transmembrane signaling receptor activity
EBA05_10185	COG0840	transmembrane signaling receptor activity
EBA05_10190	COG0840	transmembrane signaling receptor activity
EBA05_10220	COG0840	transmembrane signaling receptor activity
EBA05_10225	COG2826	transposase and inactivated derivatives, IS30 family
EBA05_10245	COG0745	RESPONSE REGULATOR receiver
EBA05_10255	COG0835	chemotaxis
EBA05_10260	COG1192	Involved in chromosome partitioning
EBA05_10265	COG1360	Flagellar Motor Protein
EBA05_10270	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EBA05_10290	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EBA05_10330	COG3039	Transposase
EBA05_10395	COG0643	Histidine kinase
EBA05_10395	COG2198	Histidine kinase
EBA05_10415	COG0455	bacterial-type flagellum organization
EBA05_10440	COG3300	MHYT domain
EBA05_10440	COG5001	Diguanylate cyclase
EBA05_10445	COG5001	Diguanylate cyclase
EBA05_10445	COG3300	MHYT domain
EBA05_10450	COG1684	flagellar biosynthetic protein fliR
EBA05_10455	COG1987	bacterial-type flagellum assembly
EBA05_10465	COG3190	flagellar
EBA05_10515	COG1677	Flagellar hook-basal body complex protein FliE
EBA05_10550	COG1028	Short-chain dehydrogenase reductase Sdr
EBA05_10560	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EBA05_10575	COG2204	response regulator
EBA05_10580	COG2201	protein-glutamate methylesterase activity
EBA05_10610	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EBA05_10615	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EBA05_10630	COG3951	Flagellar rod assembly protein muramidase FlgJ
EBA05_10630	COG1705	Flagellar rod assembly protein muramidase FlgJ
EBA05_10635	COG1706	bacterial-type flagellum-dependent cell motility
EBA05_10640	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EBA05_10645	COG4786	Flagellar basal body rod
EBA05_10655	COG4787	bacterial-type flagellum-dependent cell motility
EBA05_10660	COG1749	Flagellar hook protein flgE
EBA05_10665	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EBA05_10670	COG1558	bacterial-type flagellum-dependent cell motility
EBA05_10680	COG0784	Response regulator, receiver
EBA05_10680	COG0835	chemotaxis
EBA05_10700	COG5002	protein histidine kinase activity
EBA05_10710	COG4585	Histidine kinase
EBA05_10745	COG0482	sulfurtransferase activity
EBA05_10755	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EBA05_10760	COG0542	response to heat
EBA05_10765	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EBA05_10785	COG0492	ferredoxin-NADP+ reductase activity
EBA05_10790	COG1674	ftsk spoiiie
EBA05_10815	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EBA05_10835	COG0038	chloride channel
EBA05_10840	COG0183	Belongs to the thiolase family
EBA05_10845	COG1024	Enoyl-CoA hydratase
EBA05_10845	COG1250	3-hydroxyacyl-CoA dehydrogenase
EBA05_10855	COG0105	UTP biosynthetic process
EBA05_10880	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EBA05_10885	COG1160	GTP binding
EBA05_10890	COG0303	'Molybdopterin
EBA05_10900	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EBA05_10910	COG2826	transposase and inactivated derivatives, IS30 family
EBA05_10935	COG0746	molybdenum cofactor guanylyltransferase activity
EBA05_10960	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EBA05_10960	COG1648	precorrin-2 dehydrogenase activity
EBA05_11000	COG3039	Transposase
EBA05_11025	COG5001	Diguanylate cyclase
EBA05_11045	COG4566	intracellular signal transduction
EBA05_11085	COG3501	Rhs element vgr protein
EBA05_11175	COG1024	Enoyl-CoA hydratase
EBA05_11180	COG1024	Enoyl-CoA hydratase
EBA05_11190	COG1024	Enoyl-CoA hydratase
EBA05_11205	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EBA05_11315	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EBA05_11320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EBA05_11375	COG1858	cytochrome C peroxidase
EBA05_11405	COG0515	serine threonine protein kinase
EBA05_11410	COG0631	protein serine/threonine phosphatase activity
EBA05_11445	COG3501	Rhs element vgr protein
EBA05_11470	COG2826	transposase and inactivated derivatives, IS30 family
EBA05_11485	COG3039	Transposase
EBA05_11570	COG3039	Transposase
EBA05_11585	COG2154	pterin-4-alpha-carbinolamine dehydratase
EBA05_11600	COG3064	Membrane
EBA05_11610	COG1530	ribonuclease E activity
EBA05_11645	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EBA05_11695	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EBA05_11720	COG0811	peptide transport
EBA05_11745	COG4591	ABC-type transport system involved in lipoprotein release permease component
EBA05_11760	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EBA05_11775	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EBA05_11790	COG0354	folic acid binding
EBA05_11805	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EBA05_11815	COG0363	glucosamine-6-phosphate deaminase activity
EBA05_11820	COG0129	dihydroxy-acid dehydratase activity
EBA05_11825	COG0800	Aldolase
EBA05_11905	COG2205	protein histidine kinase activity
EBA05_11905	COG0784	Response regulator, receiver
EBA05_11920	COG2183	response to ionizing radiation
EBA05_11930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA05_11930	COG0723	plastoquinol--plastocyanin reductase activity
EBA05_11945	COG3243	poly(R)-hydroxyalkanoic acid synthase
EBA05_11955	COG1183	phosphatidylcholine synthase activity
EBA05_11960	COG1028	Short-chain dehydrogenase reductase Sdr
EBA05_11975	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EBA05_11985	COG0668	transmembrane transport
EBA05_11995	COG0590	tRNA wobble adenosine to inosine editing
EBA05_12000	COG1321	iron dependent repressor
EBA05_12005	COG1914	H( )-stimulated, divalent metal cation uptake system
EBA05_12035	COG0583	DNA-binding transcription factor activity
EBA05_12060	COG0583	DNA-binding transcription factor activity
EBA05_12065	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EBA05_12075	COG0519	Catalyzes the synthesis of GMP from XMP
EBA05_12075	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EBA05_12100	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EBA05_12110	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EBA05_12115	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EBA05_12130	COG0539	negative regulation of cytoplasmic translation
EBA05_12135	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EBA05_12140	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EBA05_12150	COG2957	Belongs to the agmatine deiminase family
EBA05_12160	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EBA05_12185	COG0395	ABC-type sugar transport system, permease component
EBA05_12190	COG1175	transmembrane transport
EBA05_12220	COG2350	Protein conserved in bacteria
EBA05_12225	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EBA05_12230	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EBA05_12235	COG1187	pseudouridine synthase activity
EBA05_12255	COG0436	Aminotransferase
EBA05_12260	COG4133	protoheme IX ABC transporter activity
EBA05_12310	COG1278	Cold shock
EBA05_12320	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EBA05_12325	COG4988	ABC transporter
EBA05_12335	COG1271	oxidase subunit
EBA05_12405	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EBA05_12410	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EBA05_12415	COG0137	argininosuccinate synthase activity
EBA05_12420	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EBA05_12435	COG2166	iron-sulfur cluster assembly
EBA05_12450	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EBA05_12460	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EBA05_12475	COG4302	ethanolamine ammonia-lyase activity
EBA05_12490	COG4677	pectinesterase activity
EBA05_12525	COG0402	S-adenosylhomocysteine deaminase activity
EBA05_12545	COG1509	lysine 2,3-aminomutase activity
EBA05_12550	COG5001	Diguanylate cyclase
EBA05_12550	COG3300	MHYT domain
EBA05_12565	COG0483	inositol monophosphate 1-phosphatase activity
EBA05_12600	COG0513	Belongs to the DEAD box helicase family
EBA05_12610	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EBA05_12620	COG0625	glutathione transferase activity
EBA05_12635	COG4681	YaeQ
EBA05_12640	COG2081	HI0933 family
EBA05_12645	COG5001	Diguanylate cyclase
EBA05_12645	COG1716	ATPase activity
EBA05_12650	COG0501	Belongs to the peptidase M48B family
EBA05_12660	COG1028	Short-chain dehydrogenase reductase Sdr
EBA05_12685	COG0860	N-Acetylmuramoyl-L-alanine amidase
EBA05_12690	COG0802	atpase or kinase
EBA05_12695	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EBA05_12695	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EBA05_12700	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EBA05_12720	COG3039	Transposase
EBA05_12730	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EBA05_12780	COG0835	chemotaxis
EBA05_12785	COG0840	transmembrane signaling receptor activity
EBA05_12815	COG2969	positive regulation of protein catabolic process
EBA05_12820	COG0625	glutathione transferase activity
EBA05_12825	COG2857	Cytochrome c1
EBA05_12830	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EBA05_12835	COG0723	plastoquinol--plastocyanin reductase activity
EBA05_12845	COG0741	lytic transglycosylase activity
EBA05_12870	COG1702	phosphate starvation-inducible protein PhoH
EBA05_12890	COG4535	Mg2 and Co2 transporter CorC
EBA05_12905	COG1012	belongs to the aldehyde dehydrogenase family
EBA05_12910	COG1177	transmembrane transport
EBA05_12915	COG1176	ABC-type spermidine putrescine transport system, permease component I
EBA05_12925	COG3842	ATPase activity
EBA05_12955	COG3039	Transposase
EBA05_12980	COG0174	glutamine synthetase
EBA05_12985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA05_12990	COG3706	GGDEF domain
EBA05_12990	COG0745	RESPONSE REGULATOR receiver
EBA05_12995	COG0477	Major facilitator Superfamily
EBA05_13005	COG0243	molybdopterin cofactor binding
EBA05_13030	COG1121	(ABC) transporter
EBA05_13040	COG2733	membrane
EBA05_13055	COG3039	Transposase
EBA05_13105	COG3039	Transposase
EBA05_13115	COG2902	Dehydrogenase
EBA05_13125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EBA05_13130	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EBA05_13145	COG1609	Transcriptional regulator
EBA05_13150	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EBA05_13150	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EBA05_13155	COG1105	Belongs to the carbohydrate kinase PfkB family
EBA05_13160	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EBA05_13160	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EBA05_13170	COG3501	Rhs element vgr protein
EBA05_13210	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EBA05_13220	COG1862	Preprotein translocase
EBA05_13290	COG0405	Gamma-glutamyltransferase
EBA05_13295	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EBA05_13315	COG0742	ribosomal rna small subunit methyltransferase
EBA05_13320	COG0326	Molecular chaperone. Has ATPase activity
EBA05_13365	COG4206	TonB-dependent receptor
EBA05_13420	COG3039	Transposase
EBA05_13425	COG3039	Transposase
EBA05_13435	COG0531	amino acid
EBA05_13450	COG0006	proline dipeptidase activity
EBA05_13460	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EBA05_13475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA05_13480	COG3938	Belongs to the proline racemase family
EBA05_13490	COG0552	protein localization to endoplasmic reticulum
EBA05_13505	COG1194	a g-specific adenine glycosylase
EBA05_13515	COG4191	Histidine kinase
EBA05_13515	COG0784	Response regulator, receiver
EBA05_13520	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EBA05_13545	COG3040	lipid binding
EBA05_13555	COG1960	acyl-CoA dehydrogenase activity
EBA05_13605	COG0438	transferase activity, transferring glycosyl groups
EBA05_13610	COG0438	transferase activity, transferring glycosyl groups
EBA05_13655	COG0776	regulation of translation
EBA05_13665	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EBA05_13670	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EBA05_13675	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EBA05_13680	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EBA05_13720	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EBA05_13725	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EBA05_13730	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EBA05_13735	COG3115	cell septum assembly
EBA05_13760	COG0316	Belongs to the HesB IscA family
EBA05_13795	COG0288	reversible hydration of carbon dioxide
EBA05_13820	COG3844	kynureninase activity
EBA05_13830	COG2925	Exonuclease
EBA05_13840	COG0667	Aldo Keto reductase
EBA05_13855	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EBA05_13915	COG0494	nUDIX hydrolase
EBA05_13925	COG1024	Enoyl-CoA hydratase
EBA05_13935	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EBA05_13940	COG0659	secondary active sulfate transmembrane transporter activity
EBA05_13965	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EBA05_13970	COG0573	inorganic phosphate transmembrane transporter activity
EBA05_13975	COG0581	inorganic phosphate transmembrane transporter activity
EBA05_13985	COG0704	Plays a role in the regulation of phosphate uptake
EBA05_13995	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EBA05_14005	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EBA05_14020	COG0557	exoribonuclease II activity
EBA05_14050	COG1960	acyl-CoA dehydrogenase activity
EBA05_14060	COG0646	methionine synthase
EBA05_14060	COG1410	methionine synthase
EBA05_14065	COG1410	methionine synthase
EBA05_14065	COG0646	methionine synthase
EBA05_14075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBA05_14115	COG0386	Belongs to the glutathione peroxidase family
EBA05_14125	COG1725	Transcriptional regulator
EBA05_14130	COG1131	(ABC) transporter
EBA05_14170	COG3039	Transposase
EBA05_14200	COG2850	peptidyl-arginine hydroxylation
EBA05_14235	COG1132	(ABC) transporter
EBA05_14265	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EBA05_14280	COG0443	Heat shock 70 kDa protein
EBA05_14295	COG0497	DNA recombination
EBA05_14305	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EBA05_14315	COG2914	Belongs to the UPF0125 (RnfH) family
EBA05_14325	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EBA05_14350	COG3039	Transposase
EBA05_14405	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EBA05_14415	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EBA05_14420	COG0174	glutamine synthetase
EBA05_14450	COG3706	GGDEF domain
EBA05_14485	COG0415	Belongs to the DNA photolyase family
EBA05_14490	COG0305	Participates in initiation and elongation during chromosome replication
EBA05_14500	COG0367	asparagine synthase
EBA05_14530	COG0084	hydrolase, TatD family'
EBA05_14535	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EBA05_14575	COG0840	transmembrane signaling receptor activity
EBA05_14590	COG3039	Transposase
EBA05_14605	COG3039	Transposase
EBA05_14640	COG0386	Belongs to the glutathione peroxidase family
EBA05_14740	COG2814	Major facilitator Superfamily
EBA05_14745	COG1566	PFAM secretion protein HlyD family protein
EBA05_14760	COG2207	Transcriptional regulator
EBA05_14790	COG4774	siderophore transport
EBA05_14800	COG0367	asparagine synthase
EBA05_14805	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EBA05_14815	COG1393	Belongs to the ArsC family
EBA05_14835	COG0024	Methionine aminopeptidase
EBA05_14900	COG0575	Belongs to the CDS family
EBA05_14905	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EBA05_14910	COG0750	zinc metalloprotease
EBA05_14925	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EBA05_14955	COG0825	malonyl-CoA metabolic process
EBA05_15030	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EBA05_15045	COG2040	homocysteine
EBA05_15050	COG0833	amino acid
EBA05_15055	COG0346	lactoylglutathione lyase activity
EBA05_15075	COG2878	Part of a membrane complex involved in electron transport
EBA05_15095	COG1595	DNA-templated transcription, initiation
EBA05_15120	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EBA05_15135	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EBA05_15140	COG0251	oxidation-reduction process
EBA05_15150	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EBA05_15150	COG0392	lysyltransferase activity
EBA05_15190	COG2814	Major facilitator Superfamily
EBA05_15195	COG1902	pentaerythritol trinitrate reductase activity
EBA05_15210	COG2824	Alkylphosphonate utilization operon protein PhnA
EBA05_15220	COG1047	Peptidyl-prolyl cis-trans
EBA05_15265	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EBA05_15280	COG1451	nucleotide metabolic process
EBA05_15300	COG0183	Belongs to the thiolase family
EBA05_15315	COG3706	GGDEF domain
EBA05_15315	COG0745	RESPONSE REGULATOR receiver
EBA05_15330	COG1793	dna ligase
EBA05_15330	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EBA05_15340	COG1793	dna ligase
EBA05_15345	COG1201	RNA secondary structure unwinding
EBA05_15365	COG1278	Cold shock
EBA05_15370	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EBA05_15385	COG3046	protein related to deoxyribodipyrimidine photolyase
EBA05_15390	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
EBA05_15445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EBA05_15460	COG1024	Enoyl-CoA hydratase
EBA05_15460	COG1250	3-hydroxyacyl-CoA dehydrogenase
EBA05_15480	COG1024	Enoyl-CoA hydratase
EBA05_15485	COG1960	acyl-CoA dehydrogenase activity
EBA05_15560	COG2353	YceI-like domain
EBA05_15585	COG1760	l-serine dehydratase
EBA05_15595	COG0626	cystathionine gamma-synthase activity
EBA05_15600	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EBA05_15605	COG0739	heme binding
EBA05_15615	COG1272	protein, Hemolysin III
EBA05_15635	COG0517	IMP dehydrogenase activity
EBA05_15635	COG0516	GMP reductase activity
EBA05_15640	COG0463	Glycosyl transferase, family 2
EBA05_15650	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EBA05_15660	COG4771	TonB-dependent receptor
EBA05_15665	COG1309	transcriptional regulator
EBA05_15675	COG1960	acyl-CoA dehydrogenase activity
EBA05_15720	COG0330	HflC and HflK could
EBA05_15730	COG1742	UPF0060 membrane protein
EBA05_15735	COG3956	TIGRFAM MazG family protein
EBA05_15745	COG0494	nUDIX hydrolase
EBA05_15755	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EBA05_15760	COG0837	glucose binding
EBA05_15775	COG1388	LysM domain
EBA05_15775	COG3858	chitin binding
EBA05_15795	COG1472	Belongs to the glycosyl hydrolase 3 family
EBA05_15820	COG2801	Transposase and inactivated derivatives
EBA05_15830	COG2826	transposase and inactivated derivatives, IS30 family
EBA05_15845	COG3039	Transposase
EBA05_15900	COG3537	Alpha-1,2-mannosidase
EBA05_15945	COG3142	Participates in the control of copper homeostasis
EBA05_15950	COG1446	asparaginase
EBA05_15960	COG2304	oxidoreductase activity
EBA05_15990	COG0840	transmembrane signaling receptor activity
EBA05_15995	COG0835	chemotaxis
EBA05_16010	COG0189	ligase activity
EBA05_16020	COG1397	ADP-ribosylglycohydrolase
EBA05_16030	COG1199	ATP-dependent helicase activity
EBA05_16040	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EBA05_16055	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EBA05_16105	COG1643	Atp-dependent helicase
EBA05_16110	COG0783	Belongs to the Dps family
EBA05_16125	COG0514	ATP-dependent DNA helicase (RecQ)
EBA05_16140	COG3039	Transposase
EBA05_16155	COG1187	pseudouridine synthase activity
EBA05_16205	COG0602	queuosine metabolic process
EBA05_16215	COG2885	chlorophyll binding
EBA05_16220	COG0823	Involved in the tonB-independent uptake of proteins
EBA05_16230	COG0848	biopolymer transport protein
EBA05_16240	COG0824	Thioesterase
EBA05_16260	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EBA05_16280	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EBA05_16295	COG0477	Major facilitator Superfamily
EBA05_16330	COG0488	(ABC) transporter
EBA05_16360	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EBA05_16360	COG4651	solute:proton antiporter activity
EBA05_16390	COG0640	Transcriptional regulator
EBA05_16405	COG4772	TonB-dependent receptor
EBA05_16415	COG4264	IucA IucC family
EBA05_16420	COG2814	Major facilitator Superfamily
EBA05_16430	COG0019	diaminopimelate decarboxylase activity
EBA05_16485	COG4206	TonB-dependent receptor
EBA05_16520	COG0542	response to heat
EBA05_16545	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EBA05_16555	COG0534	Mate efflux family protein
EBA05_16605	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EBA05_16615	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EBA05_16655	COG2172	sigma factor antagonist activity
EBA05_16660	COG1366	Belongs to the anti-sigma-factor antagonist family
EBA05_16665	COG1366	Belongs to the anti-sigma-factor antagonist family
EBA05_16675	COG0326	Molecular chaperone. Has ATPase activity
EBA05_16680	COG2207	Transcriptional regulator
EBA05_16735	COG3209	COG3209 Rhs family protein
EBA05_16745	COG3209	COG3209 Rhs family protein
EBA05_16755	COG3501	Rhs element vgr protein
EBA05_16765	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EBA05_16770	COG1845	cytochrome c oxidase, subunit III
EBA05_16775	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EBA05_16795	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EBA05_16810	COG0728	peptidoglycan biosynthetic process
EBA05_16815	COG0268	Binds directly to 16S ribosomal RNA
EBA05_16835	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EBA05_16840	COG0824	Thioesterase
EBA05_16855	COG1946	Acyl-CoA thioesterase
EBA05_16865	COG1595	DNA-templated transcription, initiation
EBA05_16920	COG1877	trehalose-phosphatase activity
EBA05_16925	COG3387	PFAM Glycoside hydrolase 15-related
EBA05_16960	COG0564	pseudouridine synthase activity
EBA05_16965	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EBA05_16970	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EBA05_16970	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EBA05_16985	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EBA05_17030	COG2194	sulfuric ester hydrolase activity
EBA05_17035	COG4969	Belongs to the N-Me-Phe pilin family
EBA05_17045	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EBA05_17050	COG0237	dephospho-CoA kinase activity
EBA05_17055	COG2205	protein histidine kinase activity
EBA05_17060	COG0745	RESPONSE REGULATOR receiver
EBA05_17080	COG3039	Transposase
EBA05_17095	COG3039	Transposase
EBA05_17110	COG2801	Transposase and inactivated derivatives
EBA05_17120	COG3039	Transposase
EBA05_17160	COG3273	potassium ion transport
EBA05_17160	COG0471	metal ion transport
EBA05_17190	COG1970	mechanosensitive ion channel activity
EBA05_17225	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EBA05_17235	COG0308	aminopeptidase N
EBA05_17240	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EBA05_17250	COG2895	sulfate adenylyltransferase (ATP) activity
EBA05_17250	COG0529	Catalyzes the synthesis of activated sulfate
EBA05_17260	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EBA05_17290	COG2198	Histidine kinase
EBA05_17290	COG0784	Response regulator, receiver
EBA05_17290	COG2205	protein histidine kinase activity
EBA05_17335	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EBA05_17340	COG3588	fructose-bisphosphate aldolase
EBA05_17350	COG0469	pyruvate kinase activity
EBA05_17375	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EBA05_17390	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EBA05_17390	COG3453	Protein conserved in bacteria
EBA05_17395	COG0725	ABC transporter, periplasmic molybdate-binding protein
EBA05_17400	COG4149	molybdate abc transporter
EBA05_17405	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EBA05_17425	COG0642	Histidine kinase
EBA05_17430	COG0745	RESPONSE REGULATOR receiver
EBA05_17440	COG1028	Short-chain dehydrogenase reductase Sdr
EBA05_17450	COG1022	Amp-dependent synthetase and ligase
EBA05_17475	COG1376	ErfK ybiS ycfS ynhG family protein
EBA05_17480	COG0739	heme binding
EBA05_17495	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EBA05_17500	COG1301	dicarboxylic acid transport
EBA05_17520	COG2304	oxidoreductase activity
EBA05_17540	COG0714	Associated with various cellular activities
EBA05_17575	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EBA05_17600	COG0254	rRNA binding
EBA05_17610	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EBA05_17620	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EBA05_17625	COG1758	RNA polymerase activity
EBA05_17640	COG1561	YicC-like family, N-terminal region
EBA05_17660	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EBA05_17690	COG0006	proline dipeptidase activity
EBA05_17735	COG2912	Transglutaminase-like superfamily
EBA05_17740	COG1773	rubredoxin
EBA05_17745	COG0352	thiamine-phosphate diphosphorylase activity
EBA05_17770	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
EBA05_17810	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EBA05_17835	COG0671	phosphoesterase, PA-phosphatase related
EBA05_17850	COG3781	membrane
EBA05_17860	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EBA05_17875	COG3039	Transposase
EBA05_17890	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
EBA05_17900	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EBA05_17925	COG3710	Transcriptional regulator
EBA05_17970	COG2226	methyltransferase
EBA05_18000	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EBA05_18005	COG1538	Outer membrane efflux protein
EBA05_18010	COG1519	Transferase
EBA05_18015	COG1560	Kdo2-lipid A biosynthetic process
EBA05_18035	COG3039	Transposase
EBA05_18045	COG2826	transposase and inactivated derivatives, IS30 family
EBA05_18110	COG3039	Transposase
EBA05_18125	COG0280	phosphate acetyltransferase
EBA05_18125	COG0281	malic enzyme
EBA05_18145	COG4191	Histidine kinase
EBA05_18160	COG0583	DNA-binding transcription factor activity
EBA05_18180	COG2197	response regulator
EBA05_18190	COG0642	Histidine kinase
EBA05_18210	COG2851	Citrate transporter
EBA05_18215	COG1028	Short-chain dehydrogenase reductase Sdr
EBA05_18225	COG1609	Transcriptional regulator
EBA05_18235	COG2211	Major facilitator Superfamily
EBA05_18265	COG0436	Aminotransferase
EBA05_18285	COG0726	polysaccharide deacetylase
EBA05_18290	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EBA05_18310	COG0402	S-adenosylhomocysteine deaminase activity
EBA05_18360	COG0242	peptide deformylase activity
EBA05_18365	COG3039	Transposase
EBA05_18400	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EBA05_18460	COG2188	Transcriptional regulator
EBA05_18475	COG1450	Type ii and iii secretion system protein
EBA05_18490	COG3166	PFAM Fimbrial assembly family protein
EBA05_18495	COG3156	type II secretion system protein K
EBA05_18500	COG4795	General secretion pathway protein
EBA05_18505	COG2165	general secretion pathway protein
EBA05_18510	COG4970	Tfp pilus assembly protein FimT
EBA05_18515	COG2165	general secretion pathway protein
EBA05_18520	COG1459	type II secretion system
EBA05_18530	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EBA05_18535	COG1404	Belongs to the peptidase S8 family
EBA05_18540	COG5295	Hep Hag repeat protein
EBA05_18550	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EBA05_18550	COG0047	phosphoribosylformylglycinamidine synthase activity
EBA05_18560	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EBA05_18565	COG4974	Belongs to the 'phage' integrase family
EBA05_18580	COG0795	lipopolysaccharide-transporting ATPase activity
EBA05_18615	COG0525	valine-tRNA ligase activity
EBA05_18645	COG2826	transposase and inactivated derivatives, IS30 family
EBA05_18655	COG2826	transposase and inactivated derivatives, IS30 family
EBA05_18680	COG1183	phosphatidylcholine synthase activity
EBA05_18705	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EBA05_18710	COG1127	ABC transporter
EBA05_18715	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EBA05_18715	COG3218	ABC-type transport auxiliary lipoprotein component
EBA05_18760	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EBA05_18765	COG0662	Cupin 2, conserved barrel domain protein
EBA05_18765	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
EBA05_18795	COG2086	electron transfer activity
EBA05_18865	COG0626	cystathionine gamma-synthase activity
EBA05_18895	COG0625	glutathione transferase activity
EBA05_18910	COG0513	Belongs to the DEAD box helicase family
EBA05_18920	COG0720	synthase
EBA05_18935	COG1956	GAF domain-containing protein
EBA05_18945	COG0546	phosphoglycolate phosphatase activity
EBA05_18975	COG0339	signal peptide processing
EBA05_19025	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EBA05_19115	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EBA05_19125	COG0356	it plays a direct role in the translocation of protons across the membrane
EBA05_19145	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EBA05_19155	COG0508	dehydrogenase complex catalyzes the overall conversion of
EBA05_19190	COG2011	ABC-type metal ion transport system permease component
EBA05_19200	COG0697	spore germination
EBA05_19235	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EBA05_19240	COG1187	pseudouridine synthase activity
EBA05_19245	COG2813	Specifically methylates the guanine in position
EBA05_19275	COG2202	Pas domain
EBA05_19275	COG2205	protein histidine kinase activity
EBA05_19300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA05_19305	COG1522	sequence-specific DNA binding
EBA05_19350	COG0745	RESPONSE REGULATOR receiver
EBA05_19365	COG1404	Belongs to the peptidase S8 family
EBA05_19380	COG0842	Transport permease protein
EBA05_19385	COG1131	(ABC) transporter
EBA05_19390	COG0025	NhaP-type Na H and K H
EBA05_19400	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EBA05_19410	COG1573	uracil-dna glycosylase
EBA05_19420	COG3384	dioxygenase
EBA05_19450	COG3590	peptidase
EBA05_19470	COG0531	amino acid
EBA05_19495	COG3685	Protein conserved in bacteria
EBA05_19500	COG3546	catalase activity
EBA05_19525	COG3039	Transposase
EBA05_19555	COG1271	oxidase subunit
EBA05_19560	COG1294	oxidase, subunit
EBA05_19595	COG1063	alcohol dehydrogenase
EBA05_19700	COG1473	amidohydrolase
EBA05_19705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EBA05_19710	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EBA05_19735	COG5383	Protein conserved in bacteria
EBA05_19785	COG3023	N-Acetylmuramoyl-L-alanine amidase
EBA05_19795	COG4948	Mandelate Racemase Muconate Lactonizing
EBA05_19820	COG0531	amino acid
EBA05_19840	COG4682	membrane
EBA05_19845	COG2133	pyrroloquinoline quinone binding
EBA05_19865	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EBA05_19875	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EBA05_19880	COG1610	YqeY-like protein
EBA05_19900	COG1295	ribonuclease BN
EBA05_19905	COG0358	DNA primase activity
EBA05_19965	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
EBA05_19980	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EBA05_20045	COG0739	heme binding
EBA05_20060	COG2211	Major facilitator Superfamily
EBA05_20065	COG0708	Exodeoxyribonuclease III
EBA05_20080	COG1192	Involved in chromosome partitioning
EBA05_20085	COG1475	DNA binding
EBA05_20100	COG0463	Glycosyl transferase, family 2
EBA05_20125	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EBA05_20150	COG4221	oxidoreductase activity
EBA05_20190	COG1166	arginine decarboxylase activity
EBA05_20240	COG0606	chelatase, subunit chli
EBA05_20265	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EBA05_20285	COG3039	Transposase
EBA05_20340	COG1090	epimerase
EBA05_20350	COG0642	Histidine kinase
EBA05_20365	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EBA05_20400	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EBA05_20410	COG1595	DNA-templated transcription, initiation
EBA05_20415	COG0753	catalase activity
EBA05_20440	COG0697	spore germination
EBA05_20465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EBA05_20470	COG0180	Tryptophanyl-tRNA synthetase
EBA05_20475	COG3237	CsbD-like
EBA05_20530	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EBA05_20530	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EBA05_20540	COG3228	Belongs to the MtfA family
EBA05_20555	COG2205	protein histidine kinase activity
EBA05_20560	COG0745	RESPONSE REGULATOR receiver
EBA05_20570	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EBA05_20625	COG3039	Transposase
EBA05_20630	COG1566	PFAM secretion protein HlyD family protein
EBA05_20645	COG1199	ATP-dependent helicase activity
EBA05_20690	COG0583	DNA-binding transcription factor activity
EBA05_20740	COG0625	glutathione transferase activity
EBA05_20750	COG2826	transposase and inactivated derivatives, IS30 family
EBA05_20780	COG4555	ABC transporter
EBA05_20790	COG1476	TRANSCRIPTIONal
EBA05_20810	COG1230	cation diffusion facilitator family transporter
EBA05_20815	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EBA05_20820	COG1131	(ABC) transporter
EBA05_20825	COG0842	Transport permease protein
EBA05_20835	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EBA05_20870	COG2951	lytic endotransglycosylase activity
EBA05_20885	COG1196	nuclear chromosome segregation
EBA05_20890	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EBA05_20900	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EBA05_20915	COG0045	succinate-CoA ligase (ADP-forming) activity
EBA05_20915	COG1042	CoA-binding domain protein
EBA05_20915	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EBA05_20925	COG2239	Acts as a magnesium transporter
EBA05_20950	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EBA05_20955	COG3387	PFAM Glycoside hydrolase 15-related
EBA05_20970	COG3100	YcgL domain-containing protein
EBA05_20975	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EBA05_20985	COG0463	Glycosyl transferase, family 2
EBA05_21000	COG1028	Short-chain dehydrogenase reductase Sdr
EBA05_21030	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EBA05_21045	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EBA05_21165	COG0210	DNA helicase
EBA05_21185	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EBA05_21200	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EBA05_21215	COG2159	amidohydrolase
EBA05_21220	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EBA05_21225	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EBA05_21245	COG0357	Ribosomal RNA small subunit methyltransferase G
EBA05_21250	COG3540	Alkaline phosphatase
EBA05_21260	COG2091	lysine biosynthetic process via aminoadipic acid
EBA05_21275	COG0708	Exodeoxyribonuclease III
EBA05_21290	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EBA05_21295	COG3162	membrane
EBA05_21350	COG1028	Short-chain dehydrogenase reductase Sdr
EBA05_21355	COG0179	Fumarylacetoacetate (FAA) hydrolase
EBA05_21365	COG4948	Mandelate Racemase Muconate Lactonizing
EBA05_21370	COG3254	rhamnose metabolic process
EBA05_21375	COG0738	Major facilitator superfamily
EBA05_21380	COG1414	Transcriptional regulator
EBA05_21390	COG2205	protein histidine kinase activity
EBA05_21400	COG3459	Glycosyltransferase 36 associated
EBA05_21405	COG2211	Major facilitator Superfamily
EBA05_21410	COG3265	gluconokinase activity
EBA05_21415	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EBA05_21445	COG3039	Transposase
EBA05_21455	COG3039	Transposase
EBA05_21460	COG2911	Protein conserved in bacteria
EBA05_21465	COG0729	surface antigen
EBA05_21470	COG4771	TonB-dependent receptor
EBA05_21475	COG0457	Tetratricopeptide repeat
EBA05_21485	COG0752	glycyl-tRNA synthetase alpha subunit
EBA05_21490	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EBA05_21500	COG0519	Catalyzes the synthesis of GMP from XMP
EBA05_21500	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EBA05_21510	COG0805	protein transport
EBA05_21515	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EBA05_21520	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EBA05_21530	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EBA05_21560	COG2974	May be involved in recombination
EBA05_21565	COG0037	tRNA processing
EBA05_21590	COG3661	Belongs to the glycosyl hydrolase 67 family
EBA05_21600	COG4948	Mandelate Racemase Muconate Lactonizing
EBA05_21610	COG1472	Belongs to the glycosyl hydrolase 3 family
EBA05_21615	COG0246	Mannitol dehydrogenase
EBA05_21650	COG2826	transposase and inactivated derivatives, IS30 family
EBA05_21675	COG3693	PFAM glycoside hydrolase, family 10
EBA05_21700	COG2211	Major facilitator Superfamily
EBA05_21715	COG3039	Transposase
EBA05_21750	COG2937	Belongs to the GPAT DAPAT family
EBA05_21790	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EBA05_21810	COG0210	DNA helicase
EBA05_21825	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
EBA05_21890	COG0676	glucose-6-phosphate 1-epimerase activity
EBA05_21905	COG0730	response to heat
EBA05_21940	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EBA05_21945	COG0302	gtp cyclohydrolase
EBA05_21975	COG2826	transposase and inactivated derivatives, IS30 family
EBA05_21985	COG0477	Major facilitator Superfamily
EBA05_22000	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EBA05_22045	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EBA05_22095	COG3237	CsbD-like
EBA05_22115	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBA05_22170	COG4772	TonB-dependent receptor
EBA05_22180	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EBA05_22210	COG3039	Transposase
EBA05_22260	COG0564	pseudouridine synthase activity
EBA05_22275	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EBA05_22295	COG3039	Transposase
EBA05_22315	COG3039	Transposase
EBA05_22340	COG3039	Transposase
EBA05_22410	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EBA05_22420	COG1074	ATP-dependent DNA helicase activity
EBA05_22425	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EBA05_22440	COG3039	Transposase
EBA05_22445	COG3039	Transposase
EBA05_22455	COG1136	(ABC) transporter
EBA05_22475	COG1127	ABC transporter
EBA05_22480	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EBA05_22485	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EBA05_22500	COG2853	Lipoprotein
EBA05_22525	COG0386	Belongs to the glutathione peroxidase family
EBA05_22535	COG1322	Protein conserved in bacteria
EBA05_22540	COG3039	Transposase
EBA05_22565	COG1929	Belongs to the glycerate kinase type-1 family
EBA05_22570	COG2271	Major facilitator Superfamily
EBA05_22585	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EBA05_22595	COG0861	Integral membrane protein TerC family
EBA05_22610	COG0584	glycerophosphoryl diester phosphodiesterase
EBA05_22620	COG0671	phosphoesterase, PA-phosphatase related
EBA05_22625	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EBA05_22630	COG0726	polysaccharide deacetylase
EBA05_22645	COG0230	Belongs to the bacterial ribosomal protein bL34 family