locus-tag	class	description
EBA06_00025	COG0187	DNA topoisomerase II activity
EBA06_00035	COG0501	Belongs to the peptidase M48B family
EBA06_00065	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EBA06_00095	COG3039	Transposase
EBA06_00145	COG0793	Belongs to the peptidase S41A family
EBA06_00150	COG4942	peptidase
EBA06_00160	COG2234	aminopeptidase activity
EBA06_00170	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA06_00185	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA06_00195	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA06_00205	COG1064	alcohol dehydrogenase
EBA06_00230	COG0493	'glutamate synthase
EBA06_00235	COG0069	glutamate synthase activity
EBA06_00235	COG0067	glutamate synthase
EBA06_00235	COG0070	glutamate synthase
EBA06_00305	COG1111	helicase
EBA06_00305	COG1205	dead DEAH box helicase
EBA06_00310	COG1272	protein, Hemolysin III
EBA06_00340	COG2032	superoxide dismutase activity
EBA06_00345	COG2204	response regulator
EBA06_00350	COG3852	Histidine kinase
EBA06_00355	COG0004	ammonium transporteR
EBA06_00360	COG0347	Belongs to the P(II) protein family
EBA06_00365	COG0174	glutamine synthetase
EBA06_00420	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EBA06_00430	COG2062	phosphohistidine phosphatase, SixA
EBA06_00435	COG0489	protein tyrosine kinase activity
EBA06_00455	COG1396	sequence-specific DNA binding
EBA06_00460	COG3550	peptidyl-serine autophosphorylation
EBA06_00465	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
EBA06_00470	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EBA06_00485	COG0517	IMP dehydrogenase activity
EBA06_00485	COG1125	glycine betaine transport
EBA06_00500	COG1119	ATPase activity
EBA06_00515	COG1752	Esterase of the alpha-beta hydrolase superfamily
EBA06_00525	COG1522	sequence-specific DNA binding
EBA06_00530	COG3186	Phenylalanine-4-hydroxylase
EBA06_00560	COG1609	Transcriptional regulator
EBA06_00600	COG0366	Alpha amylase catalytic
EBA06_00605	COG0366	Alpha amylase catalytic
EBA06_00615	COG3039	Transposase
EBA06_00625	COG0183	Belongs to the thiolase family
EBA06_00665	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EBA06_00670	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EBA06_00685	COG0028	Belongs to the TPP enzyme family
EBA06_00690	COG4191	Histidine kinase
EBA06_00715	COG3039	Transposase
EBA06_00725	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EBA06_00740	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EBA06_00745	COG3177	Filamentation induced by cAMP protein fic
EBA06_00750	COG0596	Alpha beta hydrolase
EBA06_00765	COG0318	PFAM AMP-dependent synthetase and ligase
EBA06_00770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EBA06_00785	COG1181	Belongs to the D-alanine--D-alanine ligase family
EBA06_00815	COG0564	pseudouridine synthase activity
EBA06_00845	COG0339	signal peptide processing
EBA06_00900	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EBA06_00905	COG1960	acyl-CoA dehydrogenase activity
EBA06_00960	COG0697	spore germination
EBA06_00970	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EBA06_00975	COG1846	Transcriptional regulator
EBA06_00980	COG1764	response to oxidative stress
EBA06_01005	COG3501	Rhs element vgr protein
EBA06_01030	COG0656	L-ascorbic acid biosynthetic process
EBA06_01045	COG2130	NADP-dependent
EBA06_01060	COG1187	pseudouridine synthase activity
EBA06_01075	COG1643	Atp-dependent helicase
EBA06_01085	COG4807	Protein conserved in bacteria
EBA06_01090	COG2072	flavoprotein involved in K transport
EBA06_01110	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EBA06_01115	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EBA06_01155	COG3039	Transposase
EBA06_01200	COG0084	hydrolase, TatD family'
EBA06_01220	COG0583	DNA-binding transcription factor activity
EBA06_01225	COG2814	Major facilitator Superfamily
EBA06_01235	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EBA06_01240	COG1902	pentaerythritol trinitrate reductase activity
EBA06_01270	COG0745	RESPONSE REGULATOR receiver
EBA06_01290	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EBA06_01295	COG0583	DNA-binding transcription factor activity
EBA06_01325	COG0702	epimerase
EBA06_01330	COG1733	regulation of RNA biosynthetic process
EBA06_01365	COG3039	Transposase
EBA06_01385	COG3501	Rhs element vgr protein
EBA06_01410	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EBA06_01480	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EBA06_01485	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EBA06_01495	COG3485	protocatechuate 3,4-dioxygenase
EBA06_01500	COG3485	protocatechuate 3,4-dioxygenase
EBA06_01515	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EBA06_01520	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EBA06_01535	COG1414	Transcriptional regulator
EBA06_01625	COG1040	competence protein
EBA06_01630	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EBA06_01730	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EBA06_01805	COG1511	domain protein
EBA06_01805	COG3264	Mechanosensitive ion channel
EBA06_01815	COG3039	Transposase
EBA06_01820	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EBA06_01830	COG2354	Protein conserved in bacteria
EBA06_01840	COG0745	RESPONSE REGULATOR receiver
EBA06_01840	COG3706	GGDEF domain
EBA06_01855	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EBA06_01880	COG0702	epimerase
EBA06_01890	COG1028	Short-chain dehydrogenase reductase Sdr
EBA06_01935	COG0513	Belongs to the DEAD box helicase family
EBA06_01945	COG3039	Transposase
EBA06_01975	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EBA06_01990	COG3104	oligopeptide transport
EBA06_02020	COG1320	monovalent cation:proton antiporter activity
EBA06_02025	COG2212	antiporter activity
EBA06_02035	COG0651	ATP synthesis coupled electron transport
EBA06_02040	COG1006	Multisubunit Na H antiporter MnhC subunit
EBA06_02045	COG2111	Na H antiporter
EBA06_02045	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EBA06_02080	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EBA06_02090	COG0456	acetyltransferase
EBA06_02135	COG0134	indole-3-glycerol-phosphate synthase activity
EBA06_02145	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EBA06_02190	COG2906	2 iron, 2 sulfur cluster binding
EBA06_02240	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
EBA06_02260	COG2814	Major facilitator Superfamily
EBA06_02270	COG2814	Major facilitator Superfamily
EBA06_02275	COG1289	transmembrane transporter activity
EBA06_02285	COG0151	Belongs to the GarS family
EBA06_02290	COG0138	bifunctional purine biosynthesis protein purh
EBA06_02295	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EBA06_02305	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EBA06_02360	COG0439	Biotin carboxylase
EBA06_02370	COG0511	ligase activity, forming carbon-carbon bonds
EBA06_02390	COG1324	tolerance protein
EBA06_02410	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EBA06_02430	COG0534	Mate efflux family protein
EBA06_02435	COG0616	signal peptide processing
EBA06_02445	COG1028	Short-chain dehydrogenase reductase Sdr
EBA06_02465	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EBA06_02465	COG1754	DNA topoisomerase type I activity
EBA06_02485	COG0758	DNA mediated transformation
EBA06_02490	COG1652	LysM domain
EBA06_02495	COG0242	peptide deformylase activity
EBA06_02505	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EBA06_02505	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EBA06_02555	COG1560	Kdo2-lipid A biosynthetic process
EBA06_02565	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EBA06_02595	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EBA06_02600	COG3118	belongs to the thioredoxin family
EBA06_02610	COG2884	Cell division ATP-binding protein ftsE
EBA06_02615	COG2177	Part of the ABC transporter FtsEX involved in
EBA06_02620	COG3437	response regulator, receiver
EBA06_02630	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EBA06_02635	COG2860	membrane
EBA06_02640	COG1252	NADH dehydrogenase
EBA06_02660	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EBA06_02680	COG3039	Transposase
EBA06_02695	COG3039	Transposase
EBA06_02705	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EBA06_02720	COG3386	PFAM SMP-30 Gluconolaconase
EBA06_02735	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EBA06_02780	COG2353	YceI-like domain
EBA06_02835	COG3501	Rhs element vgr protein
EBA06_02895	COG4221	oxidoreductase activity
EBA06_02950	COG0697	spore germination
EBA06_02955	COG4305	rare lipoprotein A
EBA06_02960	COG5297	Belongs to the glycosyl hydrolase family 6
EBA06_02970	COG1113	amino acid transport
EBA06_02980	COG0598	Magnesium transport protein CorA
EBA06_03060	COG3300	MHYT domain
EBA06_03060	COG5001	Diguanylate cyclase
EBA06_03085	COG5297	Belongs to the glycosyl hydrolase family 6
EBA06_03085	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA06_03090	COG0659	secondary active sulfate transmembrane transporter activity
EBA06_03095	COG3706	GGDEF domain
EBA06_03125	COG3275	phosphorelay sensor kinase activity
EBA06_03160	COG1505	serine-type exopeptidase activity
EBA06_03180	COG2832	Protein of unknown function (DUF454)
EBA06_03200	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EBA06_03210	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EBA06_03245	COG3300	MHYT domain
EBA06_03245	COG5001	Diguanylate cyclase
EBA06_03250	COG0308	aminopeptidase N
EBA06_03270	COG1077	Cell shape determining protein MreB Mrl
EBA06_03275	COG1792	Involved in formation and maintenance of cell shape
EBA06_03290	COG0772	Belongs to the SEDS family
EBA06_03315	COG2951	lytic endotransglycosylase activity
EBA06_03320	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EBA06_03325	COG1686	Belongs to the peptidase S11 family
EBA06_03365	COG1056	cytidyltransferase-related domain
EBA06_03365	COG1051	belongs to the nudix hydrolase family
EBA06_03400	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EBA06_03405	COG0673	inositol 2-dehydrogenase activity
EBA06_03410	COG2823	Periplasmic or secreted lipoprotein
EBA06_03415	COG4251	negative regulation of phosphorylation
EBA06_03420	COG0784	Response regulator, receiver
EBA06_03425	COG4191	Histidine kinase
EBA06_03430	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EBA06_03455	COG3039	Transposase
EBA06_03475	COG3250	beta-galactosidase activity
EBA06_03500	COG1609	Transcriptional regulator
EBA06_03505	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EBA06_03510	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EBA06_03525	COG1215	transferase activity, transferring glycosyl groups
EBA06_03530	COG1649	PFAM Uncharacterised BCR, COG1649
EBA06_03530	COG0726	polysaccharide deacetylase
EBA06_03550	COG3039	Transposase
EBA06_03635	COG2205	protein histidine kinase activity
EBA06_03640	COG0745	RESPONSE REGULATOR receiver
EBA06_03665	COG3791	Glutathione-dependent formaldehyde-activating
EBA06_03680	COG3039	Transposase
EBA06_03695	COG0488	(ABC) transporter
EBA06_03725	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EBA06_03735	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EBA06_03735	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EBA06_03765	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EBA06_03790	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EBA06_03795	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EBA06_03805	COG2205	protein histidine kinase activity
EBA06_03810	COG0745	RESPONSE REGULATOR receiver
EBA06_03840	COG0277	FAD linked oxidase domain protein
EBA06_03895	COG3116	cell division
EBA06_03910	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EBA06_03915	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EBA06_03935	COG1181	Belongs to the D-alanine--D-alanine ligase family
EBA06_03940	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EBA06_03965	COG1196	nuclear chromosome segregation
EBA06_03965	COG0741	lytic transglycosylase activity
EBA06_03965	COG0739	heme binding
EBA06_03980	COG0494	nUDIX hydrolase
EBA06_03995	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EBA06_04010	COG3321	synthase
EBA06_04010	COG1028	Short-chain dehydrogenase reductase Sdr
EBA06_04010	COG0604	alcohol dehydrogenase
EBA06_04070	COG2226	methyltransferase
EBA06_04100	COG2826	transposase and inactivated derivatives, IS30 family
EBA06_04125	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EBA06_04140	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EBA06_04150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBA06_04155	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EBA06_04165	COG0667	Aldo Keto reductase
EBA06_04195	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EBA06_04205	COG2175	clavaminate synthase activity
EBA06_04215	COG4181	ATPase activity
EBA06_04230	COG0642	Histidine kinase
EBA06_04245	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EBA06_04285	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EBA06_04310	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EBA06_04325	COG0123	including yeast histone deacetylase and acetoin utilization protein
EBA06_04330	COG2096	Adenosyltransferase
EBA06_04345	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EBA06_04350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EBA06_04370	COG1802	Transcriptional regulator
EBA06_04380	COG3384	dioxygenase
EBA06_04385	COG0583	DNA-binding transcription factor activity
EBA06_04390	COG0318	PFAM AMP-dependent synthetase and ligase
EBA06_04400	COG1024	Enoyl-CoA hydratase
EBA06_04420	COG3386	PFAM SMP-30 Gluconolaconase
EBA06_04470	COG2197	response regulator
EBA06_04480	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EBA06_04485	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EBA06_04490	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EBA06_04500	COG0583	DNA-binding transcription factor activity
EBA06_04505	COG3634	alkyl hydroperoxide reductase activity
EBA06_04515	COG2890	protein-(glutamine-N5) methyltransferase activity
EBA06_04555	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EBA06_04555	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EBA06_04570	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EBA06_04595	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EBA06_04600	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EBA06_04625	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EBA06_04635	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EBA06_04665	COG1295	ribonuclease BN
EBA06_04670	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EBA06_04675	COG1254	Belongs to the acylphosphatase family
EBA06_04690	COG0521	Mo-molybdopterin cofactor biosynthetic process
EBA06_04705	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EBA06_04730	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EBA06_04745	COG0012	GTP binding
EBA06_04775	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EBA06_04780	COG0250	Participates in transcription elongation, termination and antitermination
EBA06_04795	COG0081	regulation of translation
EBA06_04800	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EBA06_04820	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EBA06_04845	COG0051	transcription antitermination factor activity, RNA binding
EBA06_04860	COG0089	rRNA binding
EBA06_04865	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EBA06_04885	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EBA06_04890	COG0255	Belongs to the universal ribosomal protein uL29 family
EBA06_04895	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EBA06_04905	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EBA06_04915	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EBA06_04935	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EBA06_04940	COG1841	ribosomal large subunit assembly
EBA06_04945	COG0200	Binds to the 23S rRNA
EBA06_04950	COG0201	protein transport
EBA06_04955	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EBA06_04970	COG0202	RNA polymerase activity
EBA06_04975	COG0203	ribosomal protein L17
EBA06_04990	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
EBA06_05015	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EBA06_05025	COG0625	glutathione transferase activity
EBA06_05055	COG3039	Transposase
EBA06_05075	COG1902	pentaerythritol trinitrate reductase activity
EBA06_05075	COG0446	pyridine nucleotide-disulphide oxidoreductase
EBA06_05080	COG0604	alcohol dehydrogenase
EBA06_05110	COG0156	8-amino-7-oxononanoate synthase activity
EBA06_05115	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EBA06_05120	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EBA06_05125	COG4208	sulfate ABC transporter
EBA06_05130	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EBA06_05140	COG1063	alcohol dehydrogenase
EBA06_05165	COG0406	alpha-ribazole phosphatase activity
EBA06_05180	COG0285	dihydrofolate synthase activity
EBA06_05200	COG2833	Protein of unknown function (DUF455)
EBA06_05230	COG0671	phosphoesterase, PA-phosphatase related
EBA06_05235	COG0438	transferase activity, transferring glycosyl groups
EBA06_05245	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EBA06_05250	COG5002	protein histidine kinase activity
EBA06_05260	COG4783	chaperone-mediated protein folding
EBA06_05275	COG0473	3-isopropylmalate dehydrogenase activity
EBA06_05320	COG3039	Transposase
EBA06_05345	COG0544	peptidyl-prolyl cis-trans isomerase activity
EBA06_05350	COG0740	serine-type endopeptidase activity
EBA06_05385	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EBA06_05410	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EBA06_05425	COG0631	protein serine/threonine phosphatase activity
EBA06_05460	COG0859	PFAM glycosyl transferase family 9
EBA06_05470	COG1234	tRNA 3'-trailer cleavage
EBA06_05475	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EBA06_05490	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EBA06_05495	COG0314	molybdopterin synthase activity
EBA06_05530	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EBA06_05540	COG0537	adenosine 5'-monophosphoramidase activity
EBA06_05560	COG0714	Associated with various cellular activities
EBA06_05580	COG1399	metal-binding, possibly nucleic acid-binding protein
EBA06_05605	COG1028	Short-chain dehydrogenase reductase Sdr
EBA06_05620	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EBA06_05625	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EBA06_05660	COG3829	transcription factor binding
EBA06_05700	COG3039	Transposase
EBA06_05775	COG0330	HflC and HflK could
EBA06_05780	COG0330	HflC and HflK could
EBA06_05790	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EBA06_05795	COG0308	aminopeptidase N
EBA06_05810	COG0732	type I restriction modification DNA specificity domain
EBA06_05825	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
EBA06_05865	COG0406	alpha-ribazole phosphatase activity
EBA06_05865	COG0328	RNA-DNA hybrid ribonuclease activity
EBA06_05910	COG0587	DNA-directed DNA polymerase activity
EBA06_05930	COG1297	OPT oligopeptide transporter protein
EBA06_05945	COG1506	peptidase
EBA06_05945	COG0823	Involved in the tonB-independent uptake of proteins
EBA06_05955	COG1917	Cupin 2, conserved barrel domain protein
EBA06_05955	COG2207	Transcriptional regulator
EBA06_06000	COG0753	catalase activity
EBA06_06040	COG3551	Protein conserved in bacteria
EBA06_06070	COG2194	sulfuric ester hydrolase activity
EBA06_06080	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EBA06_06085	COG0745	RESPONSE REGULATOR receiver
EBA06_06090	COG0642	Histidine kinase
EBA06_06100	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EBA06_06105	COG2894	cell division
EBA06_06120	COG4585	Histidine kinase
EBA06_06125	COG2197	response regulator
EBA06_06140	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EBA06_06165	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EBA06_06230	COG3501	Rhs element vgr protein
EBA06_06240	COG2826	transposase and inactivated derivatives, IS30 family
EBA06_06265	COG3039	Transposase
EBA06_06380	COG3501	Rhs element vgr protein
EBA06_06445	COG1842	Phage shock protein A
EBA06_06470	COG0754	glutathionylspermidine amidase activity
EBA06_06550	COG0531	amino acid
EBA06_06555	COG2197	response regulator
EBA06_06570	COG1113	amino acid transport
EBA06_06600	COG3039	Transposase
EBA06_06610	COG1294	oxidase, subunit
EBA06_06620	COG2239	Acts as a magnesium transporter
EBA06_06630	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EBA06_06635	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EBA06_06650	COG3039	Transposase
EBA06_06675	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EBA06_06690	COG1137	ATPase activity
EBA06_06695	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EBA06_06705	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EBA06_06715	COG0271	Belongs to the BolA IbaG family
EBA06_06720	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EBA06_06745	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EBA06_06770	COG0628	permease
EBA06_06780	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EBA06_06785	COG3178	'Phosphotransferase
EBA06_06795	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EBA06_06800	COG1555	photosystem II stabilization
EBA06_06820	COG3039	Transposase
EBA06_06840	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EBA06_06845	COG0719	Fe-S assembly protein
EBA06_06850	COG0396	ATPase activity
EBA06_06855	COG0719	Fe-S assembly protein
EBA06_06860	COG1959	2 iron, 2 sulfur cluster binding
EBA06_06915	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EBA06_06950	COG0519	Catalyzes the synthesis of GMP from XMP
EBA06_06965	COG1678	Uncharacterized ACR, COG1678
EBA06_06975	COG0540	Belongs to the ATCase OTCase family
EBA06_06985	COG1764	response to oxidative stress
EBA06_06995	COG0384	phenazine biosynthesis protein PhzF
EBA06_07005	COG0527	aspartate kinase activity
EBA06_07035	COG3039	Transposase
EBA06_07045	COG0142	geranyltranstransferase activity
EBA06_07050	COG0629	single-stranded DNA binding
EBA06_07055	COG4251	negative regulation of phosphorylation
EBA06_07055	COG2203	Gaf domain
EBA06_07055	COG3706	GGDEF domain
EBA06_07055	COG5001	Diguanylate cyclase
EBA06_07100	COG2879	small protein
EBA06_07105	COG1966	Carbon starvation protein
EBA06_07110	COG1741	Belongs to the pirin family
EBA06_07120	COG3501	Rhs element vgr protein
EBA06_07205	COG1515	deoxyribonuclease V activity
EBA06_07225	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EBA06_07230	COG2200	EAL domain
EBA06_07230	COG2202	Pas domain
EBA06_07230	COG2199	diguanylate cyclase activity
EBA06_07235	COG0835	chemotaxis
EBA06_07240	COG0840	transmembrane signaling receptor activity
EBA06_07250	COG2198	Histidine kinase
EBA06_07250	COG0643	Histidine kinase
EBA06_07260	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EBA06_07270	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EBA06_07310	COG0735	belongs to the Fur family
EBA06_07340	COG2826	transposase and inactivated derivatives, IS30 family
EBA06_07430	COG3039	Transposase
EBA06_07495	COG5001	Diguanylate cyclase
EBA06_07495	COG5002	protein histidine kinase activity
EBA06_07500	COG1187	pseudouridine synthase activity
EBA06_07525	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EBA06_07530	COG0475	glutathione-regulated potassium exporter activity
EBA06_07535	COG5002	protein histidine kinase activity
EBA06_07535	COG5000	phosphorelay sensor kinase activity
EBA06_07540	COG0745	RESPONSE REGULATOR receiver
EBA06_07545	COG1538	Outer membrane efflux protein
EBA06_07570	COG1132	(ABC) transporter
EBA06_07595	COG3039	Transposase
EBA06_07640	COG3118	belongs to the thioredoxin family
EBA06_07670	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EBA06_07690	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EBA06_07715	COG2968	Membrane
EBA06_07725	COG1530	ribonuclease E activity
EBA06_07730	COG3164	Protein of unknown function
EBA06_07740	COG0312	modulator of DNA gyrase
EBA06_07745	COG3028	Belongs to the UPF0307 family
EBA06_07750	COG0312	modulator of DNA gyrase
EBA06_07765	COG4104	PAAR repeat-containing protein
EBA06_07775	COG0142	geranyltranstransferase activity
EBA06_07780	COG1722	exodeoxyribonuclease VII activity
EBA06_07785	COG0037	tRNA processing
EBA06_07790	COG1785	Belongs to the alkaline phosphatase family
EBA06_07795	COG1301	dicarboxylic acid transport
EBA06_07800	COG4106	trans-aconitate 2-methyltransferase activity
EBA06_07810	COG0791	NLP P60 protein
EBA06_07815	COG0791	NLP P60 protein
EBA06_07820	COG1047	Peptidyl-prolyl cis-trans
EBA06_07825	COG2311	Membrane
EBA06_07830	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA06_07860	COG3039	Transposase
EBA06_07870	COG2826	transposase and inactivated derivatives, IS30 family
EBA06_07900	COG2826	transposase and inactivated derivatives, IS30 family
EBA06_07905	COG3039	Transposase
EBA06_07920	COG0489	protein tyrosine kinase activity
EBA06_07930	COG0717	Belongs to the dCTP deaminase family
EBA06_07945	COG3039	Transposase
EBA06_07965	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EBA06_07975	COG3039	Transposase
EBA06_07985	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EBA06_08000	COG2826	transposase and inactivated derivatives, IS30 family
EBA06_08010	COG0433	COG0433 Predicted ATPase
EBA06_08040	COG2890	protein-(glutamine-N5) methyltransferase activity
EBA06_08050	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EBA06_08055	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EBA06_08090	COG0133	tryptophan synthase activity
EBA06_08165	COG1028	Short-chain dehydrogenase reductase Sdr
EBA06_08185	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EBA06_08205	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EBA06_08210	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EBA06_08215	COG1034	ATP synthesis coupled electron transport
EBA06_08220	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EBA06_08225	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EBA06_08235	COG0713	ATP synthesis coupled electron transport
EBA06_08250	COG1007	ATP synthesis coupled electron transport
EBA06_08265	COG0195	Participates in both transcription termination and antitermination
EBA06_08270	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EBA06_08285	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EBA06_08320	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EBA06_08325	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EBA06_08335	COG2095	MarC family integral membrane protein
EBA06_08350	COG3039	Transposase
EBA06_08355	COG1611	Belongs to the LOG family
EBA06_08400	COG4969	Belongs to the N-Me-Phe pilin family
EBA06_08405	COG0556	nucleotide-excision repair
EBA06_08435	COG3723	Recombinational DNA repair protein, rece pathway
EBA06_08525	COG0270	DNA (cytosine-5-)-methyltransferase activity
EBA06_08730	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EBA06_08740	COG2986	histidine ammonia-lyase
EBA06_08790	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EBA06_08795	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EBA06_08800	COG0077	Prephenate dehydratase
EBA06_08800	COG1605	Chorismate mutase
EBA06_08830	COG3039	Transposase
EBA06_08840	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EBA06_08855	COG0583	DNA-binding transcription factor activity
EBA06_08870	COG2336	PFAM SpoVT AbrB
EBA06_08910	COG0840	transmembrane signaling receptor activity
EBA06_08935	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
EBA06_08940	COG4191	Histidine kinase
EBA06_08940	COG0784	Response regulator, receiver
EBA06_08955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EBA06_08975	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EBA06_08990	COG1595	DNA-templated transcription, initiation
EBA06_09040	COG2244	polysaccharide biosynthetic process
EBA06_09070	COG2264	protein methyltransferase activity
EBA06_09080	COG0438	transferase activity, transferring glycosyl groups
EBA06_09095	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
EBA06_09100	COG1132	(ABC) transporter
EBA06_09110	COG0477	Major facilitator Superfamily
EBA06_09130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EBA06_09145	COG1253	flavin adenine dinucleotide binding
EBA06_09160	COG0306	phosphate transporter
EBA06_09200	COG0148	phosphopyruvate hydratase activity
EBA06_09205	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EBA06_09230	COG2840	Smr protein MutS2
EBA06_09245	COG1238	metal cluster binding
EBA06_09260	COG1534	Rna-binding protein
EBA06_09270	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EBA06_09275	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EBA06_09285	COG1923	regulation of RNA biosynthetic process
EBA06_09290	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EBA06_09295	COG1546	Belongs to the CinA family
EBA06_09320	COG2137	regulation of response to DNA damage stimulus
EBA06_09330	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EBA06_09385	COG1741	Belongs to the pirin family
EBA06_09390	COG0583	DNA-binding transcription factor activity
EBA06_09415	COG0352	thiamine-phosphate diphosphorylase activity
EBA06_09415	COG0351	phosphomethylpyrimidine kinase
EBA06_09425	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EBA06_09430	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EBA06_09445	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EBA06_09455	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EBA06_09460	COG3734	2-keto-3-deoxy-galactonokinase
EBA06_09475	COG0800	Aldolase
EBA06_09500	COG1070	Carbohydrate kinase
EBA06_09510	COG0477	Major facilitator Superfamily
EBA06_09530	COG0860	N-Acetylmuramoyl-L-alanine amidase
EBA06_09545	COG0617	tRNA 3'-terminal CCA addition
EBA06_09565	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EBA06_09595	COG1472	Belongs to the glycosyl hydrolase 3 family
EBA06_09615	COG4251	negative regulation of phosphorylation
EBA06_09615	COG2203	Gaf domain
EBA06_09615	COG5001	Diguanylate cyclase
EBA06_09615	COG3706	GGDEF domain
EBA06_09625	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA06_09635	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
EBA06_09650	COG0671	phosphoesterase, PA-phosphatase related
EBA06_09670	COG1794	racemase activity, acting on amino acids and derivatives
EBA06_09680	COG0697	spore germination
EBA06_09685	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EBA06_09710	COG1012	belongs to the aldehyde dehydrogenase family
EBA06_09770	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EBA06_09785	COG0124	histidyl-tRNA synthetase
EBA06_09840	COG0140	phosphoribosyl-ATP diphosphatase activity
EBA06_09840	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EBA06_09870	COG0235	Class ii aldolase
EBA06_09875	COG0531	amino acid
EBA06_09880	COG0531	amino acid
EBA06_09890	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EBA06_09895	COG0277	FAD linked oxidase domain protein
EBA06_09975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EBA06_09980	COG2258	MOSC domain
EBA06_09985	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EBA06_09990	COG0505	Belongs to the CarA family
EBA06_10000	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EBA06_10005	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EBA06_10015	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EBA06_10030	COG3279	Response regulator of the LytR AlgR family
EBA06_10055	COG2198	Histidine kinase
EBA06_10055	COG0784	Response regulator, receiver
EBA06_10055	COG2205	protein histidine kinase activity
EBA06_10060	COG1024	Enoyl-CoA hydratase
EBA06_10065	COG0318	PFAM AMP-dependent synthetase and ligase
EBA06_10095	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EBA06_10125	COG0840	transmembrane signaling receptor activity
EBA06_10135	COG0835	chemotaxis
EBA06_10150	COG0840	transmembrane signaling receptor activity
EBA06_10155	COG0840	transmembrane signaling receptor activity
EBA06_10160	COG0840	transmembrane signaling receptor activity
EBA06_10175	COG0840	transmembrane signaling receptor activity
EBA06_10185	COG0840	transmembrane signaling receptor activity
EBA06_10190	COG0840	transmembrane signaling receptor activity
EBA06_10220	COG0840	transmembrane signaling receptor activity
EBA06_10225	COG2826	transposase and inactivated derivatives, IS30 family
EBA06_10245	COG0745	RESPONSE REGULATOR receiver
EBA06_10255	COG0835	chemotaxis
EBA06_10260	COG1192	Involved in chromosome partitioning
EBA06_10265	COG1360	Flagellar Motor Protein
EBA06_10270	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EBA06_10290	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EBA06_10330	COG3039	Transposase
EBA06_10395	COG0643	Histidine kinase
EBA06_10395	COG2198	Histidine kinase
EBA06_10415	COG0455	bacterial-type flagellum organization
EBA06_10440	COG5001	Diguanylate cyclase
EBA06_10440	COG3300	MHYT domain
EBA06_10445	COG5001	Diguanylate cyclase
EBA06_10445	COG3300	MHYT domain
EBA06_10450	COG1684	flagellar biosynthetic protein fliR
EBA06_10455	COG1987	bacterial-type flagellum assembly
EBA06_10465	COG3190	flagellar
EBA06_10515	COG1677	Flagellar hook-basal body complex protein FliE
EBA06_10550	COG1028	Short-chain dehydrogenase reductase Sdr
EBA06_10560	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EBA06_10575	COG2204	response regulator
EBA06_10580	COG2201	protein-glutamate methylesterase activity
EBA06_10610	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EBA06_10615	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EBA06_10630	COG1705	Flagellar rod assembly protein muramidase FlgJ
EBA06_10630	COG3951	Flagellar rod assembly protein muramidase FlgJ
EBA06_10635	COG1706	bacterial-type flagellum-dependent cell motility
EBA06_10640	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EBA06_10645	COG4786	Flagellar basal body rod
EBA06_10655	COG4787	bacterial-type flagellum-dependent cell motility
EBA06_10660	COG1749	Flagellar hook protein flgE
EBA06_10665	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EBA06_10670	COG1558	bacterial-type flagellum-dependent cell motility
EBA06_10680	COG0784	Response regulator, receiver
EBA06_10680	COG0835	chemotaxis
EBA06_10700	COG5002	protein histidine kinase activity
EBA06_10710	COG4585	Histidine kinase
EBA06_10745	COG0482	sulfurtransferase activity
EBA06_10755	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EBA06_10760	COG0542	response to heat
EBA06_10765	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EBA06_10785	COG0492	ferredoxin-NADP+ reductase activity
EBA06_10790	COG1674	ftsk spoiiie
EBA06_10815	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EBA06_10835	COG0038	chloride channel
EBA06_10840	COG0183	Belongs to the thiolase family
EBA06_10845	COG1024	Enoyl-CoA hydratase
EBA06_10845	COG1250	3-hydroxyacyl-CoA dehydrogenase
EBA06_10855	COG0105	UTP biosynthetic process
EBA06_10880	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EBA06_10885	COG1160	GTP binding
EBA06_10890	COG0303	'Molybdopterin
EBA06_10900	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EBA06_10910	COG2826	transposase and inactivated derivatives, IS30 family
EBA06_10935	COG0746	molybdenum cofactor guanylyltransferase activity
EBA06_10960	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EBA06_10960	COG1648	precorrin-2 dehydrogenase activity
EBA06_11000	COG3039	Transposase
EBA06_11025	COG5001	Diguanylate cyclase
EBA06_11045	COG4566	intracellular signal transduction
EBA06_11085	COG3501	Rhs element vgr protein
EBA06_11170	COG1024	Enoyl-CoA hydratase
EBA06_11175	COG1024	Enoyl-CoA hydratase
EBA06_11185	COG1024	Enoyl-CoA hydratase
EBA06_11200	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EBA06_11310	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EBA06_11315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EBA06_11370	COG1858	cytochrome C peroxidase
EBA06_11400	COG0515	serine threonine protein kinase
EBA06_11405	COG0631	protein serine/threonine phosphatase activity
EBA06_11440	COG3501	Rhs element vgr protein
EBA06_11465	COG2826	transposase and inactivated derivatives, IS30 family
EBA06_11480	COG3039	Transposase
EBA06_11565	COG3039	Transposase
EBA06_11580	COG2154	pterin-4-alpha-carbinolamine dehydratase
EBA06_11595	COG3064	Membrane
EBA06_11605	COG1530	ribonuclease E activity
EBA06_11640	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EBA06_11690	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EBA06_11715	COG0811	peptide transport
EBA06_11740	COG4591	ABC-type transport system involved in lipoprotein release permease component
EBA06_11755	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EBA06_11770	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EBA06_11785	COG0354	folic acid binding
EBA06_11800	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EBA06_11810	COG0363	glucosamine-6-phosphate deaminase activity
EBA06_11815	COG0129	dihydroxy-acid dehydratase activity
EBA06_11820	COG0800	Aldolase
EBA06_11900	COG2205	protein histidine kinase activity
EBA06_11900	COG0784	Response regulator, receiver
EBA06_11915	COG2183	response to ionizing radiation
EBA06_11925	COG0723	plastoquinol--plastocyanin reductase activity
EBA06_11925	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA06_11940	COG3243	poly(R)-hydroxyalkanoic acid synthase
EBA06_11950	COG1183	phosphatidylcholine synthase activity
EBA06_11955	COG1028	Short-chain dehydrogenase reductase Sdr
EBA06_11970	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EBA06_11980	COG0668	transmembrane transport
EBA06_11990	COG0590	tRNA wobble adenosine to inosine editing
EBA06_11995	COG1321	iron dependent repressor
EBA06_12000	COG1914	H( )-stimulated, divalent metal cation uptake system
EBA06_12030	COG0583	DNA-binding transcription factor activity
EBA06_12055	COG0583	DNA-binding transcription factor activity
EBA06_12060	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EBA06_12070	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EBA06_12070	COG0519	Catalyzes the synthesis of GMP from XMP
EBA06_12095	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EBA06_12105	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EBA06_12110	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EBA06_12125	COG0539	negative regulation of cytoplasmic translation
EBA06_12130	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EBA06_12135	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EBA06_12145	COG2957	Belongs to the agmatine deiminase family
EBA06_12155	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EBA06_12180	COG0395	ABC-type sugar transport system, permease component
EBA06_12185	COG1175	transmembrane transport
EBA06_12215	COG2350	Protein conserved in bacteria
EBA06_12220	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EBA06_12225	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EBA06_12230	COG1187	pseudouridine synthase activity
EBA06_12250	COG0436	Aminotransferase
EBA06_12255	COG4133	protoheme IX ABC transporter activity
EBA06_12305	COG1278	Cold shock
EBA06_12315	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EBA06_12320	COG4988	ABC transporter
EBA06_12330	COG1271	oxidase subunit
EBA06_12400	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EBA06_12405	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EBA06_12410	COG0137	argininosuccinate synthase activity
EBA06_12415	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EBA06_12430	COG2166	iron-sulfur cluster assembly
EBA06_12445	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EBA06_12455	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EBA06_12470	COG4302	ethanolamine ammonia-lyase activity
EBA06_12485	COG4677	pectinesterase activity
EBA06_12520	COG0402	S-adenosylhomocysteine deaminase activity
EBA06_12540	COG1509	lysine 2,3-aminomutase activity
EBA06_12545	COG3300	MHYT domain
EBA06_12545	COG5001	Diguanylate cyclase
EBA06_12560	COG0483	inositol monophosphate 1-phosphatase activity
EBA06_12595	COG0513	Belongs to the DEAD box helicase family
EBA06_12605	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EBA06_12615	COG0625	glutathione transferase activity
EBA06_12630	COG4681	YaeQ
EBA06_12635	COG2081	HI0933 family
EBA06_12640	COG1716	ATPase activity
EBA06_12640	COG5001	Diguanylate cyclase
EBA06_12645	COG0501	Belongs to the peptidase M48B family
EBA06_12655	COG1028	Short-chain dehydrogenase reductase Sdr
EBA06_12680	COG0860	N-Acetylmuramoyl-L-alanine amidase
EBA06_12685	COG0802	atpase or kinase
EBA06_12690	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EBA06_12690	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EBA06_12695	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EBA06_12715	COG3039	Transposase
EBA06_12725	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EBA06_12775	COG0835	chemotaxis
EBA06_12780	COG0840	transmembrane signaling receptor activity
EBA06_12810	COG2969	positive regulation of protein catabolic process
EBA06_12815	COG0625	glutathione transferase activity
EBA06_12820	COG2857	Cytochrome c1
EBA06_12825	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EBA06_12830	COG0723	plastoquinol--plastocyanin reductase activity
EBA06_12840	COG0741	lytic transglycosylase activity
EBA06_12865	COG1702	phosphate starvation-inducible protein PhoH
EBA06_12885	COG4535	Mg2 and Co2 transporter CorC
EBA06_12900	COG1012	belongs to the aldehyde dehydrogenase family
EBA06_12905	COG1177	transmembrane transport
EBA06_12910	COG1176	ABC-type spermidine putrescine transport system, permease component I
EBA06_12920	COG3842	ATPase activity
EBA06_12950	COG3039	Transposase
EBA06_12975	COG0174	glutamine synthetase
EBA06_12980	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA06_12985	COG0745	RESPONSE REGULATOR receiver
EBA06_12985	COG3706	GGDEF domain
EBA06_12990	COG0477	Major facilitator Superfamily
EBA06_13000	COG0243	molybdopterin cofactor binding
EBA06_13025	COG1121	(ABC) transporter
EBA06_13035	COG2733	membrane
EBA06_13040	COG5002	protein histidine kinase activity
EBA06_13040	COG0784	Response regulator, receiver
EBA06_13040	COG2205	protein histidine kinase activity
EBA06_13050	COG3039	Transposase
EBA06_13100	COG3039	Transposase
EBA06_13110	COG2902	Dehydrogenase
EBA06_13120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EBA06_13125	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EBA06_13140	COG1609	Transcriptional regulator
EBA06_13145	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EBA06_13145	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EBA06_13150	COG1105	Belongs to the carbohydrate kinase PfkB family
EBA06_13155	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EBA06_13155	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EBA06_13165	COG3501	Rhs element vgr protein
EBA06_13205	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EBA06_13215	COG1862	Preprotein translocase
EBA06_13285	COG0405	Gamma-glutamyltransferase
EBA06_13290	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EBA06_13310	COG0742	ribosomal rna small subunit methyltransferase
EBA06_13315	COG0326	Molecular chaperone. Has ATPase activity
EBA06_13360	COG4206	TonB-dependent receptor
EBA06_13415	COG3039	Transposase
EBA06_13420	COG3039	Transposase
EBA06_13430	COG0531	amino acid
EBA06_13445	COG0006	proline dipeptidase activity
EBA06_13455	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EBA06_13470	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA06_13475	COG3938	Belongs to the proline racemase family
EBA06_13485	COG0552	protein localization to endoplasmic reticulum
EBA06_13500	COG1194	a g-specific adenine glycosylase
EBA06_13510	COG4191	Histidine kinase
EBA06_13510	COG0784	Response regulator, receiver
EBA06_13515	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EBA06_13540	COG3040	lipid binding
EBA06_13550	COG1960	acyl-CoA dehydrogenase activity
EBA06_13600	COG0438	transferase activity, transferring glycosyl groups
EBA06_13605	COG0438	transferase activity, transferring glycosyl groups
EBA06_13650	COG0776	regulation of translation
EBA06_13660	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EBA06_13665	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EBA06_13670	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EBA06_13675	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EBA06_13715	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EBA06_13740	COG0316	Belongs to the HesB IscA family
EBA06_13775	COG0288	reversible hydration of carbon dioxide
EBA06_13800	COG3844	kynureninase activity
EBA06_13810	COG2925	Exonuclease
EBA06_13820	COG0667	Aldo Keto reductase
EBA06_13835	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EBA06_13895	COG0494	nUDIX hydrolase
EBA06_13905	COG1024	Enoyl-CoA hydratase
EBA06_13915	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EBA06_13920	COG0659	secondary active sulfate transmembrane transporter activity
EBA06_13945	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EBA06_13950	COG0573	inorganic phosphate transmembrane transporter activity
EBA06_13955	COG0581	inorganic phosphate transmembrane transporter activity
EBA06_13965	COG0704	Plays a role in the regulation of phosphate uptake
EBA06_13975	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EBA06_13985	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EBA06_14000	COG0557	exoribonuclease II activity
EBA06_14030	COG1960	acyl-CoA dehydrogenase activity
EBA06_14040	COG1410	methionine synthase
EBA06_14040	COG0646	methionine synthase
EBA06_14045	COG1410	methionine synthase
EBA06_14045	COG0646	methionine synthase
EBA06_14055	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBA06_14095	COG0386	Belongs to the glutathione peroxidase family
EBA06_14105	COG1725	Transcriptional regulator
EBA06_14110	COG1131	(ABC) transporter
EBA06_14150	COG3039	Transposase
EBA06_14180	COG2850	peptidyl-arginine hydroxylation
EBA06_14215	COG1132	(ABC) transporter
EBA06_14245	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EBA06_14260	COG0443	Heat shock 70 kDa protein
EBA06_14275	COG0497	DNA recombination
EBA06_14285	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EBA06_14295	COG2914	Belongs to the UPF0125 (RnfH) family
EBA06_14305	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EBA06_14330	COG3039	Transposase
EBA06_14385	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EBA06_14395	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EBA06_14400	COG0174	glutamine synthetase
EBA06_14430	COG3706	GGDEF domain
EBA06_14465	COG0415	Belongs to the DNA photolyase family
EBA06_14470	COG0305	Participates in initiation and elongation during chromosome replication
EBA06_14480	COG0367	asparagine synthase
EBA06_14510	COG0084	hydrolase, TatD family'
EBA06_14515	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EBA06_14555	COG0840	transmembrane signaling receptor activity
EBA06_14570	COG3039	Transposase
EBA06_14585	COG3039	Transposase
EBA06_14620	COG0386	Belongs to the glutathione peroxidase family
EBA06_14720	COG2814	Major facilitator Superfamily
EBA06_14725	COG1566	PFAM secretion protein HlyD family protein
EBA06_14740	COG2207	Transcriptional regulator
EBA06_14770	COG4774	siderophore transport
EBA06_14780	COG0367	asparagine synthase
EBA06_14785	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EBA06_14795	COG1393	Belongs to the ArsC family
EBA06_14815	COG0024	Methionine aminopeptidase
EBA06_14880	COG0575	Belongs to the CDS family
EBA06_14885	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EBA06_14890	COG0750	zinc metalloprotease
EBA06_14905	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EBA06_14935	COG0825	malonyl-CoA metabolic process
EBA06_15010	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EBA06_15025	COG2040	homocysteine
EBA06_15030	COG0833	amino acid
EBA06_15035	COG0346	lactoylglutathione lyase activity
EBA06_15055	COG2878	Part of a membrane complex involved in electron transport
EBA06_15075	COG1595	DNA-templated transcription, initiation
EBA06_15100	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EBA06_15115	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EBA06_15120	COG0251	oxidation-reduction process
EBA06_15130	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EBA06_15130	COG0392	lysyltransferase activity
EBA06_15170	COG2814	Major facilitator Superfamily
EBA06_15175	COG1902	pentaerythritol trinitrate reductase activity
EBA06_15190	COG2824	Alkylphosphonate utilization operon protein PhnA
EBA06_15200	COG1047	Peptidyl-prolyl cis-trans
EBA06_15245	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EBA06_15260	COG1451	nucleotide metabolic process
EBA06_15280	COG0183	Belongs to the thiolase family
EBA06_15295	COG0745	RESPONSE REGULATOR receiver
EBA06_15295	COG3706	GGDEF domain
EBA06_15310	COG1793	dna ligase
EBA06_15310	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EBA06_15320	COG1793	dna ligase
EBA06_15325	COG1201	RNA secondary structure unwinding
EBA06_15345	COG1278	Cold shock
EBA06_15350	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EBA06_15365	COG3046	protein related to deoxyribodipyrimidine photolyase
EBA06_15370	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
EBA06_15425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EBA06_15440	COG1250	3-hydroxyacyl-CoA dehydrogenase
EBA06_15440	COG1024	Enoyl-CoA hydratase
EBA06_15460	COG1024	Enoyl-CoA hydratase
EBA06_15465	COG1960	acyl-CoA dehydrogenase activity
EBA06_15540	COG2353	YceI-like domain
EBA06_15565	COG1760	l-serine dehydratase
EBA06_15575	COG0626	cystathionine gamma-synthase activity
EBA06_15580	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EBA06_15585	COG0739	heme binding
EBA06_15595	COG1272	protein, Hemolysin III
EBA06_15615	COG0516	GMP reductase activity
EBA06_15615	COG0517	IMP dehydrogenase activity
EBA06_15620	COG0463	Glycosyl transferase, family 2
EBA06_15630	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EBA06_15640	COG4771	TonB-dependent receptor
EBA06_15645	COG1309	transcriptional regulator
EBA06_15655	COG1960	acyl-CoA dehydrogenase activity
EBA06_15700	COG0330	HflC and HflK could
EBA06_15710	COG1742	UPF0060 membrane protein
EBA06_15715	COG3956	TIGRFAM MazG family protein
EBA06_15725	COG0494	nUDIX hydrolase
EBA06_15735	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EBA06_15740	COG0837	glucose binding
EBA06_15755	COG3858	chitin binding
EBA06_15755	COG1388	LysM domain
EBA06_15775	COG1472	Belongs to the glycosyl hydrolase 3 family
EBA06_15800	COG2801	Transposase and inactivated derivatives
EBA06_15810	COG2826	transposase and inactivated derivatives, IS30 family
EBA06_15825	COG3039	Transposase
EBA06_15880	COG3537	Alpha-1,2-mannosidase
EBA06_15925	COG3142	Participates in the control of copper homeostasis
EBA06_15930	COG1446	asparaginase
EBA06_15940	COG2304	oxidoreductase activity
EBA06_15970	COG0840	transmembrane signaling receptor activity
EBA06_15975	COG0835	chemotaxis
EBA06_15990	COG0189	ligase activity
EBA06_16000	COG1397	ADP-ribosylglycohydrolase
EBA06_16010	COG1199	ATP-dependent helicase activity
EBA06_16020	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EBA06_16035	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EBA06_16085	COG1643	Atp-dependent helicase
EBA06_16090	COG0783	Belongs to the Dps family
EBA06_16105	COG0514	ATP-dependent DNA helicase (RecQ)
EBA06_16120	COG3039	Transposase
EBA06_16135	COG1187	pseudouridine synthase activity
EBA06_16185	COG0602	queuosine metabolic process
EBA06_16195	COG2885	chlorophyll binding
EBA06_16200	COG0823	Involved in the tonB-independent uptake of proteins
EBA06_16210	COG0848	biopolymer transport protein
EBA06_16220	COG0824	Thioesterase
EBA06_16240	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EBA06_16260	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EBA06_16275	COG0477	Major facilitator Superfamily
EBA06_16310	COG0488	(ABC) transporter
EBA06_16340	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EBA06_16340	COG4651	solute:proton antiporter activity
EBA06_16370	COG0640	Transcriptional regulator
EBA06_16385	COG4772	TonB-dependent receptor
EBA06_16395	COG4264	IucA IucC family
EBA06_16400	COG2814	Major facilitator Superfamily
EBA06_16410	COG0019	diaminopimelate decarboxylase activity
EBA06_16465	COG4206	TonB-dependent receptor
EBA06_16500	COG0542	response to heat
EBA06_16525	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EBA06_16535	COG0534	Mate efflux family protein
EBA06_16585	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EBA06_16595	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EBA06_16635	COG2172	sigma factor antagonist activity
EBA06_16640	COG1366	Belongs to the anti-sigma-factor antagonist family
EBA06_16645	COG1366	Belongs to the anti-sigma-factor antagonist family
EBA06_16655	COG0326	Molecular chaperone. Has ATPase activity
EBA06_16660	COG2207	Transcriptional regulator
EBA06_16715	COG3209	COG3209 Rhs family protein
EBA06_16725	COG3209	COG3209 Rhs family protein
EBA06_16735	COG3501	Rhs element vgr protein
EBA06_16745	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EBA06_16750	COG1845	cytochrome c oxidase, subunit III
EBA06_16755	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EBA06_16775	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EBA06_16790	COG0728	peptidoglycan biosynthetic process
EBA06_16795	COG0268	Binds directly to 16S ribosomal RNA
EBA06_16815	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EBA06_16820	COG0824	Thioesterase
EBA06_16835	COG1946	Acyl-CoA thioesterase
EBA06_16845	COG1595	DNA-templated transcription, initiation
EBA06_16900	COG1877	trehalose-phosphatase activity
EBA06_16905	COG3387	PFAM Glycoside hydrolase 15-related
EBA06_16940	COG0564	pseudouridine synthase activity
EBA06_16945	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EBA06_16950	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EBA06_16950	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EBA06_16965	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EBA06_17010	COG2194	sulfuric ester hydrolase activity
EBA06_17015	COG4969	Belongs to the N-Me-Phe pilin family
EBA06_17025	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EBA06_17030	COG0237	dephospho-CoA kinase activity
EBA06_17035	COG2205	protein histidine kinase activity
EBA06_17040	COG0745	RESPONSE REGULATOR receiver
EBA06_17060	COG3039	Transposase
EBA06_17075	COG3039	Transposase
EBA06_17090	COG2801	Transposase and inactivated derivatives
EBA06_17100	COG3039	Transposase
EBA06_17140	COG0471	metal ion transport
EBA06_17140	COG3273	potassium ion transport
EBA06_17170	COG1970	mechanosensitive ion channel activity
EBA06_17205	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EBA06_17215	COG0308	aminopeptidase N
EBA06_17220	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EBA06_17230	COG0529	Catalyzes the synthesis of activated sulfate
EBA06_17230	COG2895	sulfate adenylyltransferase (ATP) activity
EBA06_17240	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EBA06_17270	COG0784	Response regulator, receiver
EBA06_17270	COG2198	Histidine kinase
EBA06_17270	COG2205	protein histidine kinase activity
EBA06_17315	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EBA06_17320	COG3588	fructose-bisphosphate aldolase
EBA06_17330	COG0469	pyruvate kinase activity
EBA06_17355	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EBA06_17370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EBA06_17370	COG3453	Protein conserved in bacteria
EBA06_17375	COG0725	ABC transporter, periplasmic molybdate-binding protein
EBA06_17380	COG4149	molybdate abc transporter
EBA06_17385	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EBA06_17405	COG0642	Histidine kinase
EBA06_17410	COG0745	RESPONSE REGULATOR receiver
EBA06_17420	COG1028	Short-chain dehydrogenase reductase Sdr
EBA06_17430	COG1022	Amp-dependent synthetase and ligase
EBA06_17460	COG1376	ErfK ybiS ycfS ynhG family protein
EBA06_17465	COG0739	heme binding
EBA06_17480	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EBA06_17485	COG1301	dicarboxylic acid transport
EBA06_17505	COG2304	oxidoreductase activity
EBA06_17525	COG0714	Associated with various cellular activities
EBA06_17560	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EBA06_17585	COG0254	rRNA binding
EBA06_17595	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EBA06_17605	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EBA06_17610	COG1758	RNA polymerase activity
EBA06_17625	COG1561	YicC-like family, N-terminal region
EBA06_17645	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EBA06_17675	COG0006	proline dipeptidase activity
EBA06_17720	COG2912	Transglutaminase-like superfamily
EBA06_17725	COG1773	rubredoxin
EBA06_17730	COG0352	thiamine-phosphate diphosphorylase activity
EBA06_17755	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
EBA06_17795	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EBA06_17820	COG0671	phosphoesterase, PA-phosphatase related
EBA06_17835	COG3781	membrane
EBA06_17845	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EBA06_17860	COG3039	Transposase
EBA06_17875	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
EBA06_17885	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EBA06_17910	COG3710	Transcriptional regulator
EBA06_17955	COG2226	methyltransferase
EBA06_17985	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EBA06_17990	COG1538	Outer membrane efflux protein
EBA06_17995	COG1519	Transferase
EBA06_18000	COG1560	Kdo2-lipid A biosynthetic process
EBA06_18020	COG3039	Transposase
EBA06_18030	COG2826	transposase and inactivated derivatives, IS30 family
EBA06_18095	COG3039	Transposase
EBA06_18110	COG0280	phosphate acetyltransferase
EBA06_18110	COG0281	malic enzyme
EBA06_18130	COG4191	Histidine kinase
EBA06_18145	COG0583	DNA-binding transcription factor activity
EBA06_18165	COG2197	response regulator
EBA06_18175	COG0642	Histidine kinase
EBA06_18195	COG2851	Citrate transporter
EBA06_18200	COG1028	Short-chain dehydrogenase reductase Sdr
EBA06_18210	COG1609	Transcriptional regulator
EBA06_18220	COG2211	Major facilitator Superfamily
EBA06_18250	COG0436	Aminotransferase
EBA06_18270	COG0726	polysaccharide deacetylase
EBA06_18275	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EBA06_18295	COG0402	S-adenosylhomocysteine deaminase activity
EBA06_18345	COG0242	peptide deformylase activity
EBA06_18350	COG3039	Transposase
EBA06_18385	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EBA06_18445	COG2188	Transcriptional regulator
EBA06_18460	COG1450	Type ii and iii secretion system protein
EBA06_18475	COG3166	PFAM Fimbrial assembly family protein
EBA06_18480	COG3156	type II secretion system protein K
EBA06_18485	COG4795	General secretion pathway protein
EBA06_18490	COG2165	general secretion pathway protein
EBA06_18495	COG4970	Tfp pilus assembly protein FimT
EBA06_18500	COG2165	general secretion pathway protein
EBA06_18505	COG1459	type II secretion system
EBA06_18515	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EBA06_18520	COG1404	Belongs to the peptidase S8 family
EBA06_18525	COG5295	Hep Hag repeat protein
EBA06_18535	COG0047	phosphoribosylformylglycinamidine synthase activity
EBA06_18535	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EBA06_18545	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EBA06_18550	COG4974	Belongs to the 'phage' integrase family
EBA06_18565	COG0795	lipopolysaccharide-transporting ATPase activity
EBA06_18600	COG0525	valine-tRNA ligase activity
EBA06_18630	COG2826	transposase and inactivated derivatives, IS30 family
EBA06_18640	COG2826	transposase and inactivated derivatives, IS30 family
EBA06_18665	COG1183	phosphatidylcholine synthase activity
EBA06_18690	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EBA06_18695	COG1127	ABC transporter
EBA06_18700	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EBA06_18700	COG3218	ABC-type transport auxiliary lipoprotein component
EBA06_18745	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EBA06_18750	COG0662	Cupin 2, conserved barrel domain protein
EBA06_18750	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
EBA06_18780	COG2086	electron transfer activity
EBA06_18850	COG0626	cystathionine gamma-synthase activity
EBA06_18880	COG0625	glutathione transferase activity
EBA06_18895	COG0513	Belongs to the DEAD box helicase family
EBA06_18905	COG0720	synthase
EBA06_18920	COG1956	GAF domain-containing protein
EBA06_18930	COG0546	phosphoglycolate phosphatase activity
EBA06_18960	COG0339	signal peptide processing
EBA06_19010	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EBA06_19100	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EBA06_19110	COG0356	it plays a direct role in the translocation of protons across the membrane
EBA06_19130	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EBA06_19140	COG0508	dehydrogenase complex catalyzes the overall conversion of
EBA06_19175	COG2011	ABC-type metal ion transport system permease component
EBA06_19185	COG0697	spore germination
EBA06_19220	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EBA06_19225	COG1187	pseudouridine synthase activity
EBA06_19230	COG2813	Specifically methylates the guanine in position
EBA06_19260	COG2205	protein histidine kinase activity
EBA06_19260	COG2202	Pas domain
EBA06_19285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA06_19290	COG1522	sequence-specific DNA binding
EBA06_19335	COG0745	RESPONSE REGULATOR receiver
EBA06_19350	COG1404	Belongs to the peptidase S8 family
EBA06_19365	COG0842	Transport permease protein
EBA06_19370	COG1131	(ABC) transporter
EBA06_19375	COG0025	NhaP-type Na H and K H
EBA06_19385	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EBA06_19395	COG1573	uracil-dna glycosylase
EBA06_19405	COG3384	dioxygenase
EBA06_19435	COG3590	peptidase
EBA06_19455	COG0531	amino acid
EBA06_19480	COG3685	Protein conserved in bacteria
EBA06_19485	COG3546	catalase activity
EBA06_19510	COG3039	Transposase
EBA06_19540	COG1271	oxidase subunit
EBA06_19545	COG1294	oxidase, subunit
EBA06_19580	COG1063	alcohol dehydrogenase
EBA06_19685	COG1473	amidohydrolase
EBA06_19690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EBA06_19695	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EBA06_19720	COG5383	Protein conserved in bacteria
EBA06_19770	COG3023	N-Acetylmuramoyl-L-alanine amidase
EBA06_19780	COG4948	Mandelate Racemase Muconate Lactonizing
EBA06_19805	COG0531	amino acid
EBA06_19825	COG4682	membrane
EBA06_19830	COG2133	pyrroloquinoline quinone binding
EBA06_19850	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EBA06_19860	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EBA06_19865	COG1610	YqeY-like protein
EBA06_19885	COG1295	ribonuclease BN
EBA06_19890	COG0358	DNA primase activity
EBA06_19950	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
EBA06_19965	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EBA06_20030	COG0739	heme binding
EBA06_20045	COG2211	Major facilitator Superfamily
EBA06_20050	COG0708	Exodeoxyribonuclease III
EBA06_20065	COG1192	Involved in chromosome partitioning
EBA06_20070	COG1475	DNA binding
EBA06_20085	COG0463	Glycosyl transferase, family 2
EBA06_20110	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EBA06_20135	COG4221	oxidoreductase activity
EBA06_20175	COG1166	arginine decarboxylase activity
EBA06_20225	COG0606	chelatase, subunit chli
EBA06_20250	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EBA06_20270	COG3039	Transposase
EBA06_20325	COG1090	epimerase
EBA06_20335	COG0642	Histidine kinase
EBA06_20350	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EBA06_20385	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EBA06_20395	COG1595	DNA-templated transcription, initiation
EBA06_20400	COG0753	catalase activity
EBA06_20425	COG0697	spore germination
EBA06_20450	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EBA06_20455	COG0180	Tryptophanyl-tRNA synthetase
EBA06_20460	COG3237	CsbD-like
EBA06_20515	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EBA06_20515	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EBA06_20525	COG3228	Belongs to the MtfA family
EBA06_20540	COG2205	protein histidine kinase activity
EBA06_20545	COG0745	RESPONSE REGULATOR receiver
EBA06_20555	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EBA06_20610	COG3039	Transposase
EBA06_20615	COG1566	PFAM secretion protein HlyD family protein
EBA06_20630	COG1199	ATP-dependent helicase activity
EBA06_20675	COG0583	DNA-binding transcription factor activity
EBA06_20725	COG0625	glutathione transferase activity
EBA06_20735	COG2826	transposase and inactivated derivatives, IS30 family
EBA06_20765	COG4555	ABC transporter
EBA06_20775	COG1476	TRANSCRIPTIONal
EBA06_20795	COG1230	cation diffusion facilitator family transporter
EBA06_20800	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EBA06_20805	COG1131	(ABC) transporter
EBA06_20810	COG0842	Transport permease protein
EBA06_20820	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EBA06_20855	COG2951	lytic endotransglycosylase activity
EBA06_20870	COG1196	nuclear chromosome segregation
EBA06_20875	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EBA06_20885	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EBA06_20900	COG1042	CoA-binding domain protein
EBA06_20900	COG0045	succinate-CoA ligase (ADP-forming) activity
EBA06_20900	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EBA06_20910	COG2239	Acts as a magnesium transporter
EBA06_20935	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EBA06_20940	COG3387	PFAM Glycoside hydrolase 15-related
EBA06_20955	COG3100	YcgL domain-containing protein
EBA06_20960	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EBA06_20970	COG0463	Glycosyl transferase, family 2
EBA06_20980	COG1028	Short-chain dehydrogenase reductase Sdr
EBA06_21010	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EBA06_21025	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EBA06_21145	COG0210	DNA helicase
EBA06_21165	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EBA06_21180	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EBA06_21195	COG2159	amidohydrolase
EBA06_21200	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EBA06_21205	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EBA06_21225	COG0357	Ribosomal RNA small subunit methyltransferase G
EBA06_21230	COG3540	Alkaline phosphatase
EBA06_21240	COG2091	lysine biosynthetic process via aminoadipic acid
EBA06_21255	COG0708	Exodeoxyribonuclease III
EBA06_21270	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EBA06_21275	COG3162	membrane
EBA06_21330	COG1028	Short-chain dehydrogenase reductase Sdr
EBA06_21335	COG0179	Fumarylacetoacetate (FAA) hydrolase
EBA06_21345	COG4948	Mandelate Racemase Muconate Lactonizing
EBA06_21350	COG3254	rhamnose metabolic process
EBA06_21355	COG0738	Major facilitator superfamily
EBA06_21360	COG1414	Transcriptional regulator
EBA06_21370	COG2205	protein histidine kinase activity
EBA06_21380	COG3459	Glycosyltransferase 36 associated
EBA06_21385	COG2211	Major facilitator Superfamily
EBA06_21390	COG3265	gluconokinase activity
EBA06_21395	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EBA06_21425	COG3039	Transposase
EBA06_21435	COG3039	Transposase
EBA06_21440	COG2911	Protein conserved in bacteria
EBA06_21445	COG0729	surface antigen
EBA06_21450	COG4771	TonB-dependent receptor
EBA06_21455	COG0457	Tetratricopeptide repeat
EBA06_21465	COG0752	glycyl-tRNA synthetase alpha subunit
EBA06_21470	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EBA06_21480	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EBA06_21480	COG0519	Catalyzes the synthesis of GMP from XMP
EBA06_21490	COG0805	protein transport
EBA06_21495	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EBA06_21500	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EBA06_21510	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EBA06_21540	COG2974	May be involved in recombination
EBA06_21545	COG0037	tRNA processing
EBA06_21570	COG3661	Belongs to the glycosyl hydrolase 67 family
EBA06_21580	COG4948	Mandelate Racemase Muconate Lactonizing
EBA06_21590	COG1472	Belongs to the glycosyl hydrolase 3 family
EBA06_21595	COG0246	Mannitol dehydrogenase
EBA06_21630	COG2826	transposase and inactivated derivatives, IS30 family
EBA06_21655	COG3693	PFAM glycoside hydrolase, family 10
EBA06_21680	COG2211	Major facilitator Superfamily
EBA06_21695	COG3039	Transposase
EBA06_21730	COG2937	Belongs to the GPAT DAPAT family
EBA06_21770	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EBA06_21790	COG0210	DNA helicase
EBA06_21805	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
EBA06_21870	COG0676	glucose-6-phosphate 1-epimerase activity
EBA06_21885	COG0730	response to heat
EBA06_21920	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EBA06_21925	COG0302	gtp cyclohydrolase
EBA06_21955	COG2826	transposase and inactivated derivatives, IS30 family
EBA06_21965	COG0477	Major facilitator Superfamily
EBA06_21980	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EBA06_22025	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EBA06_22075	COG3237	CsbD-like
EBA06_22095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBA06_22150	COG4772	TonB-dependent receptor
EBA06_22160	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EBA06_22190	COG3039	Transposase
EBA06_22240	COG0564	pseudouridine synthase activity
EBA06_22255	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EBA06_22275	COG3039	Transposase
EBA06_22295	COG3039	Transposase
EBA06_22320	COG3039	Transposase
EBA06_22395	COG1074	ATP-dependent DNA helicase activity
EBA06_22400	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EBA06_22415	COG3039	Transposase
EBA06_22420	COG3039	Transposase
EBA06_22430	COG1136	(ABC) transporter
EBA06_22450	COG1127	ABC transporter
EBA06_22455	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EBA06_22460	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EBA06_22475	COG2853	Lipoprotein
EBA06_22500	COG0386	Belongs to the glutathione peroxidase family
EBA06_22510	COG1322	Protein conserved in bacteria
EBA06_22515	COG3039	Transposase
EBA06_22540	COG1929	Belongs to the glycerate kinase type-1 family
EBA06_22545	COG2271	Major facilitator Superfamily
EBA06_22560	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EBA06_22570	COG0861	Integral membrane protein TerC family
EBA06_22585	COG0584	glycerophosphoryl diester phosphodiesterase
EBA06_22595	COG0671	phosphoesterase, PA-phosphatase related
EBA06_22600	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EBA06_22605	COG0726	polysaccharide deacetylase
EBA06_22620	COG0230	Belongs to the bacterial ribosomal protein bL34 family