locus-tag	class	description
EYR02_00025	COG0187	DNA topoisomerase II activity
EYR02_00035	COG0501	Belongs to the peptidase M48B family
EYR02_00065	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EYR02_00095	COG3039	Transposase
EYR02_00150	COG0793	Belongs to the peptidase S41A family
EYR02_00155	COG4942	peptidase
EYR02_00165	COG2234	aminopeptidase activity
EYR02_00175	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EYR02_00190	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EYR02_00200	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EYR02_00210	COG1064	alcohol dehydrogenase
EYR02_00240	COG0493	'glutamate synthase
EYR02_00245	COG0067	glutamate synthase
EYR02_00245	COG0069	glutamate synthase activity
EYR02_00245	COG0070	glutamate synthase
EYR02_00315	COG1111	helicase
EYR02_00315	COG1205	dead DEAH box helicase
EYR02_00320	COG1272	protein, Hemolysin III
EYR02_00350	COG2032	superoxide dismutase activity
EYR02_00355	COG2204	response regulator
EYR02_00360	COG3852	Histidine kinase
EYR02_00365	COG0004	ammonium transporteR
EYR02_00370	COG0347	Belongs to the P(II) protein family
EYR02_00375	COG0174	glutamine synthetase
EYR02_00430	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EYR02_00440	COG2062	phosphohistidine phosphatase, SixA
EYR02_00445	COG0489	protein tyrosine kinase activity
EYR02_00465	COG1396	sequence-specific DNA binding
EYR02_00470	COG3550	peptidyl-serine autophosphorylation
EYR02_00475	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
EYR02_00480	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EYR02_00495	COG1125	glycine betaine transport
EYR02_00495	COG0517	IMP dehydrogenase activity
EYR02_00510	COG1119	ATPase activity
EYR02_00525	COG1752	Esterase of the alpha-beta hydrolase superfamily
EYR02_00535	COG1522	sequence-specific DNA binding
EYR02_00540	COG3186	Phenylalanine-4-hydroxylase
EYR02_00570	COG1609	Transcriptional regulator
EYR02_00615	COG0366	Alpha amylase catalytic
EYR02_00620	COG0366	Alpha amylase catalytic
EYR02_00630	COG3039	Transposase
EYR02_00640	COG0183	Belongs to the thiolase family
EYR02_00680	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EYR02_00685	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EYR02_00700	COG0028	Belongs to the TPP enzyme family
EYR02_00705	COG4191	Histidine kinase
EYR02_00730	COG3039	Transposase
EYR02_00740	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EYR02_00755	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EYR02_00760	COG3177	Filamentation induced by cAMP protein fic
EYR02_00765	COG0596	Alpha beta hydrolase
EYR02_00780	COG0318	PFAM AMP-dependent synthetase and ligase
EYR02_00785	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EYR02_00800	COG1181	Belongs to the D-alanine--D-alanine ligase family
EYR02_00830	COG0564	pseudouridine synthase activity
EYR02_00860	COG0339	signal peptide processing
EYR02_00910	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EYR02_00915	COG1960	acyl-CoA dehydrogenase activity
EYR02_00960	COG0523	cobalamin synthesis protein
EYR02_00970	COG0697	spore germination
EYR02_00980	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EYR02_00985	COG1846	Transcriptional regulator
EYR02_00990	COG1764	response to oxidative stress
EYR02_01015	COG3501	Rhs element vgr protein
EYR02_01040	COG0656	L-ascorbic acid biosynthetic process
EYR02_01055	COG2130	NADP-dependent
EYR02_01070	COG1187	pseudouridine synthase activity
EYR02_01085	COG1643	Atp-dependent helicase
EYR02_01095	COG4807	Protein conserved in bacteria
EYR02_01100	COG2072	flavoprotein involved in K transport
EYR02_01120	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EYR02_01125	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EYR02_01165	COG3039	Transposase
EYR02_01210	COG0084	hydrolase, TatD family'
EYR02_01230	COG0583	DNA-binding transcription factor activity
EYR02_01235	COG2814	Major facilitator Superfamily
EYR02_01245	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EYR02_01250	COG1902	pentaerythritol trinitrate reductase activity
EYR02_01280	COG0745	RESPONSE REGULATOR receiver
EYR02_01300	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EYR02_01305	COG0583	DNA-binding transcription factor activity
EYR02_01335	COG0702	epimerase
EYR02_01340	COG1733	regulation of RNA biosynthetic process
EYR02_01375	COG3039	Transposase
EYR02_01395	COG3501	Rhs element vgr protein
EYR02_01420	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EYR02_01490	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EYR02_01505	COG3485	protocatechuate 3,4-dioxygenase
EYR02_01510	COG3485	protocatechuate 3,4-dioxygenase
EYR02_01525	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EYR02_01530	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EYR02_01545	COG1414	Transcriptional regulator
EYR02_01635	COG1040	competence protein
EYR02_01640	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EYR02_01750	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EYR02_01825	COG1511	domain protein
EYR02_01825	COG3264	Mechanosensitive ion channel
EYR02_01835	COG3039	Transposase
EYR02_01840	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EYR02_01850	COG2354	Protein conserved in bacteria
EYR02_01865	COG0745	RESPONSE REGULATOR receiver
EYR02_01865	COG3706	GGDEF domain
EYR02_01880	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EYR02_01905	COG0702	epimerase
EYR02_01915	COG1028	Short-chain dehydrogenase reductase Sdr
EYR02_01960	COG0513	Belongs to the DEAD box helicase family
EYR02_01970	COG3039	Transposase
EYR02_02000	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EYR02_02015	COG3104	oligopeptide transport
EYR02_02045	COG1320	monovalent cation:proton antiporter activity
EYR02_02050	COG2212	antiporter activity
EYR02_02060	COG0651	ATP synthesis coupled electron transport
EYR02_02065	COG1006	Multisubunit Na H antiporter MnhC subunit
EYR02_02070	COG2111	Na H antiporter
EYR02_02070	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EYR02_02105	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EYR02_02115	COG0456	acetyltransferase
EYR02_02160	COG0134	indole-3-glycerol-phosphate synthase activity
EYR02_02170	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EYR02_02215	COG2906	2 iron, 2 sulfur cluster binding
EYR02_02265	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
EYR02_02285	COG2814	Major facilitator Superfamily
EYR02_02295	COG2814	Major facilitator Superfamily
EYR02_02300	COG1289	transmembrane transporter activity
EYR02_02310	COG0151	Belongs to the GarS family
EYR02_02320	COG0419	ATPase involved in DNA repair
EYR02_02325	COG0138	bifunctional purine biosynthesis protein purh
EYR02_02330	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EYR02_02340	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EYR02_02395	COG0439	Biotin carboxylase
EYR02_02405	COG0511	ligase activity, forming carbon-carbon bonds
EYR02_02425	COG1324	tolerance protein
EYR02_02445	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EYR02_02465	COG0534	Mate efflux family protein
EYR02_02470	COG0616	signal peptide processing
EYR02_02480	COG1028	Short-chain dehydrogenase reductase Sdr
EYR02_02500	COG1754	DNA topoisomerase type I activity
EYR02_02500	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EYR02_02520	COG0758	DNA mediated transformation
EYR02_02525	COG1652	LysM domain
EYR02_02530	COG0242	peptide deformylase activity
EYR02_02540	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EYR02_02540	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EYR02_02590	COG1560	Kdo2-lipid A biosynthetic process
EYR02_02600	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EYR02_02770	COG3179	chitinase
EYR02_02815	COG4695	Portal protein
EYR02_02840	COG3501	Rhs element vgr protein
EYR02_02890	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EYR02_02895	COG3118	belongs to the thioredoxin family
EYR02_02905	COG2884	Cell division ATP-binding protein ftsE
EYR02_02910	COG2177	Part of the ABC transporter FtsEX involved in
EYR02_02915	COG3437	response regulator, receiver
EYR02_02925	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EYR02_02930	COG2860	membrane
EYR02_02935	COG1252	NADH dehydrogenase
EYR02_02955	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EYR02_02975	COG3039	Transposase
EYR02_02985	COG3039	Transposase
EYR02_02995	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EYR02_03010	COG3386	PFAM SMP-30 Gluconolaconase
EYR02_03025	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EYR02_03080	COG2353	YceI-like domain
EYR02_03130	COG3501	Rhs element vgr protein
EYR02_03180	COG4221	oxidoreductase activity
EYR02_03240	COG0697	spore germination
EYR02_03245	COG4305	rare lipoprotein A
EYR02_03250	COG5297	Belongs to the glycosyl hydrolase family 6
EYR02_03260	COG1113	amino acid transport
EYR02_03270	COG0598	Magnesium transport protein CorA
EYR02_03345	COG5001	Diguanylate cyclase
EYR02_03345	COG3300	MHYT domain
EYR02_03370	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EYR02_03370	COG5297	Belongs to the glycosyl hydrolase family 6
EYR02_03375	COG0659	secondary active sulfate transmembrane transporter activity
EYR02_03380	COG3706	GGDEF domain
EYR02_03410	COG3275	phosphorelay sensor kinase activity
EYR02_03445	COG1505	serine-type exopeptidase activity
EYR02_03465	COG2832	Protein of unknown function (DUF454)
EYR02_03485	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EYR02_03495	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EYR02_03530	COG3300	MHYT domain
EYR02_03530	COG5001	Diguanylate cyclase
EYR02_03535	COG0308	aminopeptidase N
EYR02_03555	COG1077	Cell shape determining protein MreB Mrl
EYR02_03560	COG1792	Involved in formation and maintenance of cell shape
EYR02_03575	COG0772	Belongs to the SEDS family
EYR02_03600	COG2951	lytic endotransglycosylase activity
EYR02_03605	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EYR02_03610	COG1686	Belongs to the peptidase S11 family
EYR02_03650	COG1051	belongs to the nudix hydrolase family
EYR02_03650	COG1056	cytidyltransferase-related domain
EYR02_03685	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EYR02_03690	COG0673	inositol 2-dehydrogenase activity
EYR02_03695	COG2823	Periplasmic or secreted lipoprotein
EYR02_03700	COG4251	negative regulation of phosphorylation
EYR02_03705	COG0784	Response regulator, receiver
EYR02_03710	COG4191	Histidine kinase
EYR02_03715	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EYR02_03740	COG3039	Transposase
EYR02_03760	COG3250	beta-galactosidase activity
EYR02_03785	COG1609	Transcriptional regulator
EYR02_03790	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EYR02_03795	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EYR02_03810	COG1215	transferase activity, transferring glycosyl groups
EYR02_03815	COG1649	PFAM Uncharacterised BCR, COG1649
EYR02_03815	COG0726	polysaccharide deacetylase
EYR02_03835	COG3039	Transposase
EYR02_03925	COG2205	protein histidine kinase activity
EYR02_03930	COG0745	RESPONSE REGULATOR receiver
EYR02_03955	COG3791	Glutathione-dependent formaldehyde-activating
EYR02_03970	COG3039	Transposase
EYR02_03985	COG0488	(ABC) transporter
EYR02_04015	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EYR02_04025	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EYR02_04025	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EYR02_04055	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EYR02_04080	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EYR02_04085	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EYR02_04095	COG2205	protein histidine kinase activity
EYR02_04100	COG0745	RESPONSE REGULATOR receiver
EYR02_04130	COG0277	FAD linked oxidase domain protein
EYR02_04185	COG3116	cell division
EYR02_04200	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EYR02_04205	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EYR02_04225	COG1181	Belongs to the D-alanine--D-alanine ligase family
EYR02_04230	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EYR02_04255	COG0741	lytic transglycosylase activity
EYR02_04255	COG0739	heme binding
EYR02_04255	COG1196	nuclear chromosome segregation
EYR02_04270	COG0494	nUDIX hydrolase
EYR02_04285	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EYR02_04300	COG3321	synthase
EYR02_04300	COG1028	Short-chain dehydrogenase reductase Sdr
EYR02_04300	COG0604	alcohol dehydrogenase
EYR02_04360	COG2226	methyltransferase
EYR02_04405	COG2826	transposase and inactivated derivatives, IS30 family
EYR02_04430	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EYR02_04445	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EYR02_04455	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYR02_04460	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EYR02_04470	COG0667	Aldo Keto reductase
EYR02_04495	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EYR02_04505	COG2175	clavaminate synthase activity
EYR02_04515	COG4181	ATPase activity
EYR02_04530	COG0642	Histidine kinase
EYR02_04545	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EYR02_04585	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EYR02_04610	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EYR02_04625	COG0123	including yeast histone deacetylase and acetoin utilization protein
EYR02_04630	COG2096	Adenosyltransferase
EYR02_04645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EYR02_04650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EYR02_04670	COG1802	Transcriptional regulator
EYR02_04680	COG3384	dioxygenase
EYR02_04685	COG0583	DNA-binding transcription factor activity
EYR02_04690	COG0318	PFAM AMP-dependent synthetase and ligase
EYR02_04700	COG1024	Enoyl-CoA hydratase
EYR02_04720	COG3386	PFAM SMP-30 Gluconolaconase
EYR02_04770	COG2197	response regulator
EYR02_04780	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EYR02_04785	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EYR02_04790	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EYR02_04800	COG0583	DNA-binding transcription factor activity
EYR02_04805	COG3634	alkyl hydroperoxide reductase activity
EYR02_04815	COG2890	protein-(glutamine-N5) methyltransferase activity
EYR02_04855	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EYR02_04855	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EYR02_04895	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EYR02_04900	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EYR02_04925	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EYR02_04935	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EYR02_04965	COG1295	ribonuclease BN
EYR02_04970	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYR02_04975	COG1254	Belongs to the acylphosphatase family
EYR02_04990	COG0521	Mo-molybdopterin cofactor biosynthetic process
EYR02_05005	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EYR02_05030	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EYR02_05045	COG0012	GTP binding
EYR02_05075	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EYR02_05080	COG0250	Participates in transcription elongation, termination and antitermination
EYR02_05095	COG0081	regulation of translation
EYR02_05100	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EYR02_05120	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EYR02_05145	COG0051	transcription antitermination factor activity, RNA binding
EYR02_05160	COG0089	rRNA binding
EYR02_05165	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EYR02_05185	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EYR02_05190	COG0255	Belongs to the universal ribosomal protein uL29 family
EYR02_05195	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EYR02_05205	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EYR02_05215	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EYR02_05235	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EYR02_05240	COG1841	ribosomal large subunit assembly
EYR02_05245	COG0200	Binds to the 23S rRNA
EYR02_05250	COG0201	protein transport
EYR02_05255	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EYR02_05270	COG0202	RNA polymerase activity
EYR02_05275	COG0203	ribosomal protein L17
EYR02_05295	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
EYR02_05320	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EYR02_05330	COG0625	glutathione transferase activity
EYR02_05360	COG3039	Transposase
EYR02_05380	COG0446	pyridine nucleotide-disulphide oxidoreductase
EYR02_05380	COG1902	pentaerythritol trinitrate reductase activity
EYR02_05385	COG0604	alcohol dehydrogenase
EYR02_05415	COG0156	8-amino-7-oxononanoate synthase activity
EYR02_05420	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EYR02_05425	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EYR02_05430	COG4208	sulfate ABC transporter
EYR02_05435	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EYR02_05445	COG1063	alcohol dehydrogenase
EYR02_05470	COG0406	alpha-ribazole phosphatase activity
EYR02_05480	COG0285	dihydrofolate synthase activity
EYR02_05500	COG2833	Protein of unknown function (DUF455)
EYR02_05530	COG0671	phosphoesterase, PA-phosphatase related
EYR02_05535	COG0438	transferase activity, transferring glycosyl groups
EYR02_05545	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EYR02_05550	COG5002	protein histidine kinase activity
EYR02_05560	COG4783	chaperone-mediated protein folding
EYR02_05575	COG0473	3-isopropylmalate dehydrogenase activity
EYR02_05615	COG3039	Transposase
EYR02_05640	COG0544	peptidyl-prolyl cis-trans isomerase activity
EYR02_05645	COG0740	serine-type endopeptidase activity
EYR02_05680	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EYR02_05705	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EYR02_05720	COG0631	protein serine/threonine phosphatase activity
EYR02_05755	COG0859	PFAM glycosyl transferase family 9
EYR02_05765	COG1234	tRNA 3'-trailer cleavage
EYR02_05770	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EYR02_05785	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EYR02_05790	COG0314	molybdopterin synthase activity
EYR02_05825	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EYR02_05835	COG0537	adenosine 5'-monophosphoramidase activity
EYR02_05855	COG0714	Associated with various cellular activities
EYR02_05875	COG1399	metal-binding, possibly nucleic acid-binding protein
EYR02_05900	COG1028	Short-chain dehydrogenase reductase Sdr
EYR02_05915	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EYR02_05920	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EYR02_05950	COG3829	transcription factor binding
EYR02_06060	COG0330	HflC and HflK could
EYR02_06065	COG0330	HflC and HflK could
EYR02_06075	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EYR02_06080	COG0308	aminopeptidase N
EYR02_06095	COG0732	type I restriction modification DNA specificity domain
EYR02_06110	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
EYR02_06150	COG0406	alpha-ribazole phosphatase activity
EYR02_06150	COG0328	RNA-DNA hybrid ribonuclease activity
EYR02_06195	COG0587	DNA-directed DNA polymerase activity
EYR02_06215	COG1297	OPT oligopeptide transporter protein
EYR02_06235	COG0823	Involved in the tonB-independent uptake of proteins
EYR02_06235	COG1506	peptidase
EYR02_06245	COG2207	Transcriptional regulator
EYR02_06245	COG1917	Cupin 2, conserved barrel domain protein
EYR02_06290	COG0753	catalase activity
EYR02_06330	COG3551	Protein conserved in bacteria
EYR02_06360	COG2194	sulfuric ester hydrolase activity
EYR02_06370	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EYR02_06375	COG0745	RESPONSE REGULATOR receiver
EYR02_06380	COG0642	Histidine kinase
EYR02_06390	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EYR02_06395	COG2894	cell division
EYR02_06410	COG4585	Histidine kinase
EYR02_06415	COG2197	response regulator
EYR02_06430	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EYR02_06455	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EYR02_06520	COG3501	Rhs element vgr protein
EYR02_06530	COG2826	transposase and inactivated derivatives, IS30 family
EYR02_06555	COG3039	Transposase
EYR02_06635	COG3501	Rhs element vgr protein
EYR02_06705	COG1842	Phage shock protein A
EYR02_06730	COG0754	glutathionylspermidine amidase activity
EYR02_06810	COG0531	amino acid
EYR02_06815	COG2197	response regulator
EYR02_06830	COG1113	amino acid transport
EYR02_06860	COG3039	Transposase
EYR02_06870	COG1294	oxidase, subunit
EYR02_06880	COG2239	Acts as a magnesium transporter
EYR02_06890	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EYR02_06895	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYR02_06910	COG3039	Transposase
EYR02_06935	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYR02_06950	COG1137	ATPase activity
EYR02_06955	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EYR02_06965	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EYR02_06975	COG0271	Belongs to the BolA IbaG family
EYR02_06980	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EYR02_07005	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EYR02_07030	COG0628	permease
EYR02_07040	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EYR02_07045	COG3178	'Phosphotransferase
EYR02_07055	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EYR02_07060	COG1555	photosystem II stabilization
EYR02_07085	COG3039	Transposase
EYR02_07105	COG3039	Transposase
EYR02_07110	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EYR02_07115	COG0719	Fe-S assembly protein
EYR02_07120	COG0396	ATPase activity
EYR02_07125	COG0719	Fe-S assembly protein
EYR02_07130	COG1959	2 iron, 2 sulfur cluster binding
EYR02_07185	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EYR02_07220	COG0519	Catalyzes the synthesis of GMP from XMP
EYR02_07235	COG1678	Uncharacterized ACR, COG1678
EYR02_07245	COG0540	Belongs to the ATCase OTCase family
EYR02_07255	COG1764	response to oxidative stress
EYR02_07265	COG0384	phenazine biosynthesis protein PhzF
EYR02_07275	COG0527	aspartate kinase activity
EYR02_07305	COG3039	Transposase
EYR02_07315	COG0142	geranyltranstransferase activity
EYR02_07320	COG0629	single-stranded DNA binding
EYR02_07325	COG2203	Gaf domain
EYR02_07325	COG3706	GGDEF domain
EYR02_07325	COG4251	negative regulation of phosphorylation
EYR02_07325	COG5001	Diguanylate cyclase
EYR02_07370	COG2879	small protein
EYR02_07375	COG1966	Carbon starvation protein
EYR02_07380	COG1741	Belongs to the pirin family
EYR02_07390	COG3501	Rhs element vgr protein
EYR02_07485	COG1515	deoxyribonuclease V activity
EYR02_07505	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EYR02_07510	COG2202	Pas domain
EYR02_07510	COG2200	EAL domain
EYR02_07510	COG2199	diguanylate cyclase activity
EYR02_07515	COG0835	chemotaxis
EYR02_07520	COG0840	transmembrane signaling receptor activity
EYR02_07530	COG0643	Histidine kinase
EYR02_07530	COG2198	Histidine kinase
EYR02_07545	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EYR02_07555	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EYR02_07595	COG0735	belongs to the Fur family
EYR02_07625	COG2826	transposase and inactivated derivatives, IS30 family
EYR02_07770	COG5001	Diguanylate cyclase
EYR02_07770	COG5002	protein histidine kinase activity
EYR02_07775	COG1187	pseudouridine synthase activity
EYR02_07800	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EYR02_07805	COG0475	glutathione-regulated potassium exporter activity
EYR02_07810	COG5002	protein histidine kinase activity
EYR02_07810	COG5000	phosphorelay sensor kinase activity
EYR02_07815	COG0745	RESPONSE REGULATOR receiver
EYR02_07820	COG1538	Outer membrane efflux protein
EYR02_07845	COG1132	(ABC) transporter
EYR02_07870	COG3039	Transposase
EYR02_07915	COG3118	belongs to the thioredoxin family
EYR02_07945	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EYR02_07965	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EYR02_07990	COG2968	Membrane
EYR02_08000	COG1530	ribonuclease E activity
EYR02_08005	COG3164	Protein of unknown function
EYR02_08015	COG0312	modulator of DNA gyrase
EYR02_08020	COG3028	Belongs to the UPF0307 family
EYR02_08025	COG0312	modulator of DNA gyrase
EYR02_08040	COG4104	PAAR repeat-containing protein
EYR02_08050	COG0142	geranyltranstransferase activity
EYR02_08055	COG1722	exodeoxyribonuclease VII activity
EYR02_08060	COG0037	tRNA processing
EYR02_08065	COG1785	Belongs to the alkaline phosphatase family
EYR02_08070	COG1301	dicarboxylic acid transport
EYR02_08075	COG4106	trans-aconitate 2-methyltransferase activity
EYR02_08090	COG0791	NLP P60 protein
EYR02_08095	COG0791	NLP P60 protein
EYR02_08100	COG1047	Peptidyl-prolyl cis-trans
EYR02_08105	COG2311	Membrane
EYR02_08110	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYR02_08140	COG3039	Transposase
EYR02_08150	COG2826	transposase and inactivated derivatives, IS30 family
EYR02_08175	COG2826	transposase and inactivated derivatives, IS30 family
EYR02_08180	COG3039	Transposase
EYR02_08195	COG0489	protein tyrosine kinase activity
EYR02_08205	COG0717	Belongs to the dCTP deaminase family
EYR02_08220	COG3039	Transposase
EYR02_08240	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EYR02_08250	COG3039	Transposase
EYR02_08260	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EYR02_08280	COG0433	COG0433 Predicted ATPase
EYR02_08310	COG2890	protein-(glutamine-N5) methyltransferase activity
EYR02_08320	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EYR02_08325	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EYR02_08360	COG0133	tryptophan synthase activity
EYR02_08440	COG1028	Short-chain dehydrogenase reductase Sdr
EYR02_08460	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EYR02_08480	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EYR02_08485	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EYR02_08490	COG1034	ATP synthesis coupled electron transport
EYR02_08495	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EYR02_08500	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EYR02_08510	COG0713	ATP synthesis coupled electron transport
EYR02_08525	COG1007	ATP synthesis coupled electron transport
EYR02_08540	COG0195	Participates in both transcription termination and antitermination
EYR02_08545	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EYR02_08560	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EYR02_08595	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EYR02_08600	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EYR02_08610	COG2095	MarC family integral membrane protein
EYR02_08625	COG1611	Belongs to the LOG family
EYR02_08665	COG4969	Belongs to the N-Me-Phe pilin family
EYR02_08670	COG0556	nucleotide-excision repair
EYR02_08700	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EYR02_08710	COG2986	histidine ammonia-lyase
EYR02_08760	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EYR02_08765	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EYR02_08770	COG1605	Chorismate mutase
EYR02_08770	COG0077	Prephenate dehydratase
EYR02_08800	COG3039	Transposase
EYR02_08810	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EYR02_08825	COG0583	DNA-binding transcription factor activity
EYR02_08840	COG2336	PFAM SpoVT AbrB
EYR02_08880	COG0840	transmembrane signaling receptor activity
EYR02_08905	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
EYR02_08910	COG0784	Response regulator, receiver
EYR02_08910	COG4191	Histidine kinase
EYR02_08925	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYR02_08945	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EYR02_08960	COG1595	DNA-templated transcription, initiation
EYR02_09010	COG2244	polysaccharide biosynthetic process
EYR02_09040	COG2264	protein methyltransferase activity
EYR02_09050	COG0438	transferase activity, transferring glycosyl groups
EYR02_09065	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
EYR02_09070	COG1132	(ABC) transporter
EYR02_09080	COG2271	Major facilitator Superfamily
EYR02_09100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EYR02_09115	COG1253	flavin adenine dinucleotide binding
EYR02_09130	COG0306	phosphate transporter
EYR02_09170	COG0148	phosphopyruvate hydratase activity
EYR02_09175	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EYR02_09200	COG2840	Smr protein MutS2
EYR02_09215	COG1238	metal cluster binding
EYR02_09230	COG1534	Rna-binding protein
EYR02_09240	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EYR02_09245	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EYR02_09255	COG1923	regulation of RNA biosynthetic process
EYR02_09260	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EYR02_09265	COG1546	Belongs to the CinA family
EYR02_09290	COG2137	regulation of response to DNA damage stimulus
EYR02_09300	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EYR02_09350	COG1741	Belongs to the pirin family
EYR02_09355	COG0583	DNA-binding transcription factor activity
EYR02_09380	COG0352	thiamine-phosphate diphosphorylase activity
EYR02_09380	COG0351	phosphomethylpyrimidine kinase
EYR02_09390	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EYR02_09395	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EYR02_09410	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EYR02_09420	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EYR02_09425	COG3734	2-keto-3-deoxy-galactonokinase
EYR02_09440	COG0800	Aldolase
EYR02_09465	COG1070	Carbohydrate kinase
EYR02_09475	COG0477	Major facilitator Superfamily
EYR02_09495	COG0860	N-Acetylmuramoyl-L-alanine amidase
EYR02_09510	COG0617	tRNA 3'-terminal CCA addition
EYR02_09530	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EYR02_09560	COG1472	Belongs to the glycosyl hydrolase 3 family
EYR02_09580	COG5001	Diguanylate cyclase
EYR02_09580	COG2203	Gaf domain
EYR02_09580	COG3706	GGDEF domain
EYR02_09580	COG4251	negative regulation of phosphorylation
EYR02_09590	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EYR02_09600	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
EYR02_09615	COG0671	phosphoesterase, PA-phosphatase related
EYR02_09635	COG1794	racemase activity, acting on amino acids and derivatives
EYR02_09645	COG0697	spore germination
EYR02_09650	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EYR02_09675	COG1012	belongs to the aldehyde dehydrogenase family
EYR02_09740	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EYR02_09755	COG0124	histidyl-tRNA synthetase
EYR02_09810	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EYR02_09810	COG0140	phosphoribosyl-ATP diphosphatase activity
EYR02_09835	COG0235	Class ii aldolase
EYR02_09840	COG0531	amino acid
EYR02_09845	COG0531	amino acid
EYR02_09855	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EYR02_09860	COG0277	FAD linked oxidase domain protein
EYR02_09935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EYR02_09940	COG2258	MOSC domain
EYR02_09945	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EYR02_09950	COG0505	Belongs to the CarA family
EYR02_09960	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EYR02_09965	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EYR02_09975	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EYR02_09990	COG3279	Response regulator of the LytR AlgR family
EYR02_10015	COG2205	protein histidine kinase activity
EYR02_10015	COG0784	Response regulator, receiver
EYR02_10015	COG2198	Histidine kinase
EYR02_10020	COG1024	Enoyl-CoA hydratase
EYR02_10025	COG0318	PFAM AMP-dependent synthetase and ligase
EYR02_10055	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EYR02_10085	COG0840	transmembrane signaling receptor activity
EYR02_10095	COG0835	chemotaxis
EYR02_10110	COG0840	transmembrane signaling receptor activity
EYR02_10115	COG0840	transmembrane signaling receptor activity
EYR02_10120	COG0840	transmembrane signaling receptor activity
EYR02_10135	COG0840	transmembrane signaling receptor activity
EYR02_10145	COG0840	transmembrane signaling receptor activity
EYR02_10150	COG0840	transmembrane signaling receptor activity
EYR02_10180	COG0840	transmembrane signaling receptor activity
EYR02_10190	COG0745	RESPONSE REGULATOR receiver
EYR02_10200	COG0835	chemotaxis
EYR02_10205	COG1192	Involved in chromosome partitioning
EYR02_10210	COG1360	Flagellar Motor Protein
EYR02_10215	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EYR02_10235	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EYR02_10275	COG3039	Transposase
EYR02_10340	COG0643	Histidine kinase
EYR02_10340	COG2198	Histidine kinase
EYR02_10360	COG0455	bacterial-type flagellum organization
EYR02_10385	COG3300	MHYT domain
EYR02_10385	COG5001	Diguanylate cyclase
EYR02_10390	COG3300	MHYT domain
EYR02_10390	COG5001	Diguanylate cyclase
EYR02_10395	COG1684	flagellar biosynthetic protein fliR
EYR02_10400	COG1987	bacterial-type flagellum assembly
EYR02_10410	COG3190	flagellar
EYR02_10460	COG1677	Flagellar hook-basal body complex protein FliE
EYR02_10495	COG1028	Short-chain dehydrogenase reductase Sdr
EYR02_10505	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EYR02_10520	COG2204	response regulator
EYR02_10525	COG2201	protein-glutamate methylesterase activity
EYR02_10555	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EYR02_10560	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EYR02_10575	COG3951	Flagellar rod assembly protein muramidase FlgJ
EYR02_10575	COG1705	Flagellar rod assembly protein muramidase FlgJ
EYR02_10580	COG1706	bacterial-type flagellum-dependent cell motility
EYR02_10585	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EYR02_10590	COG4786	Flagellar basal body rod
EYR02_10600	COG4787	bacterial-type flagellum-dependent cell motility
EYR02_10605	COG1749	Flagellar hook protein flgE
EYR02_10610	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EYR02_10615	COG1558	bacterial-type flagellum-dependent cell motility
EYR02_10625	COG0784	Response regulator, receiver
EYR02_10625	COG0835	chemotaxis
EYR02_10645	COG5002	protein histidine kinase activity
EYR02_10655	COG4585	Histidine kinase
EYR02_10690	COG0482	sulfurtransferase activity
EYR02_10700	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EYR02_10705	COG0542	response to heat
EYR02_10710	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EYR02_10730	COG0492	ferredoxin-NADP+ reductase activity
EYR02_10735	COG1674	ftsk spoiiie
EYR02_10760	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EYR02_10780	COG0038	chloride channel
EYR02_10785	COG0183	Belongs to the thiolase family
EYR02_10790	COG1024	Enoyl-CoA hydratase
EYR02_10790	COG1250	3-hydroxyacyl-CoA dehydrogenase
EYR02_10800	COG0105	UTP biosynthetic process
EYR02_10825	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EYR02_10830	COG1160	GTP binding
EYR02_10835	COG0303	'Molybdopterin
EYR02_10845	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EYR02_10855	COG2826	transposase and inactivated derivatives, IS30 family
EYR02_10865	COG3039	Transposase
EYR02_10890	COG0746	molybdenum cofactor guanylyltransferase activity
EYR02_10915	COG1648	precorrin-2 dehydrogenase activity
EYR02_10915	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EYR02_10955	COG3039	Transposase
EYR02_10980	COG5001	Diguanylate cyclase
EYR02_10990	COG3039	Transposase
EYR02_11000	COG4566	intracellular signal transduction
EYR02_11050	COG3501	Rhs element vgr protein
EYR02_11140	COG1024	Enoyl-CoA hydratase
EYR02_11145	COG1024	Enoyl-CoA hydratase
EYR02_11155	COG1024	Enoyl-CoA hydratase
EYR02_11170	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EYR02_11195	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EYR02_11200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EYR02_11250	COG1858	cytochrome C peroxidase
EYR02_11280	COG0515	serine threonine protein kinase
EYR02_11285	COG0631	protein serine/threonine phosphatase activity
EYR02_11320	COG3501	Rhs element vgr protein
EYR02_11350	COG3039	Transposase
EYR02_11435	COG3039	Transposase
EYR02_11450	COG2154	pterin-4-alpha-carbinolamine dehydratase
EYR02_11465	COG3064	Membrane
EYR02_11475	COG1530	ribonuclease E activity
EYR02_11510	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EYR02_11560	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EYR02_11585	COG0811	peptide transport
EYR02_11610	COG4591	ABC-type transport system involved in lipoprotein release permease component
EYR02_11625	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EYR02_11640	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EYR02_11655	COG0354	folic acid binding
EYR02_11670	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EYR02_11680	COG0363	glucosamine-6-phosphate deaminase activity
EYR02_11685	COG0129	dihydroxy-acid dehydratase activity
EYR02_11690	COG0800	Aldolase
EYR02_11765	COG2205	protein histidine kinase activity
EYR02_11765	COG0784	Response regulator, receiver
EYR02_11780	COG2183	response to ionizing radiation
EYR02_11790	COG0723	plastoquinol--plastocyanin reductase activity
EYR02_11790	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYR02_11805	COG3243	poly(R)-hydroxyalkanoic acid synthase
EYR02_11815	COG1183	phosphatidylcholine synthase activity
EYR02_11820	COG1028	Short-chain dehydrogenase reductase Sdr
EYR02_11835	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EYR02_11845	COG0668	transmembrane transport
EYR02_11855	COG0590	tRNA wobble adenosine to inosine editing
EYR02_11860	COG1321	iron dependent repressor
EYR02_11865	COG1914	H( )-stimulated, divalent metal cation uptake system
EYR02_11895	COG0583	DNA-binding transcription factor activity
EYR02_11920	COG0583	DNA-binding transcription factor activity
EYR02_11925	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EYR02_11935	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EYR02_11935	COG0519	Catalyzes the synthesis of GMP from XMP
EYR02_11960	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EYR02_11970	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EYR02_11975	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EYR02_11990	COG0539	negative regulation of cytoplasmic translation
EYR02_11995	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EYR02_12000	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EYR02_12010	COG2957	Belongs to the agmatine deiminase family
EYR02_12020	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EYR02_12045	COG0395	ABC-type sugar transport system, permease component
EYR02_12050	COG1175	transmembrane transport
EYR02_12080	COG2350	Protein conserved in bacteria
EYR02_12085	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EYR02_12090	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EYR02_12095	COG1187	pseudouridine synthase activity
EYR02_12115	COG0436	Aminotransferase
EYR02_12120	COG4133	protoheme IX ABC transporter activity
EYR02_12170	COG1278	Cold shock
EYR02_12180	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EYR02_12185	COG4988	ABC transporter
EYR02_12195	COG1271	oxidase subunit
EYR02_12265	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EYR02_12270	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EYR02_12275	COG0137	argininosuccinate synthase activity
EYR02_12280	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EYR02_12295	COG2166	iron-sulfur cluster assembly
EYR02_12310	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EYR02_12320	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EYR02_12335	COG4302	ethanolamine ammonia-lyase activity
EYR02_12350	COG4677	pectinesterase activity
EYR02_12355	COG2826	transposase and inactivated derivatives, IS30 family
EYR02_12380	COG0402	S-adenosylhomocysteine deaminase activity
EYR02_12400	COG1509	lysine 2,3-aminomutase activity
EYR02_12405	COG5001	Diguanylate cyclase
EYR02_12405	COG3300	MHYT domain
EYR02_12420	COG0483	inositol monophosphate 1-phosphatase activity
EYR02_12455	COG0513	Belongs to the DEAD box helicase family
EYR02_12465	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EYR02_12475	COG0625	glutathione transferase activity
EYR02_12490	COG4681	YaeQ
EYR02_12495	COG2081	HI0933 family
EYR02_12500	COG1716	ATPase activity
EYR02_12500	COG5001	Diguanylate cyclase
EYR02_12505	COG0501	Belongs to the peptidase M48B family
EYR02_12515	COG1028	Short-chain dehydrogenase reductase Sdr
EYR02_12540	COG0860	N-Acetylmuramoyl-L-alanine amidase
EYR02_12545	COG0802	atpase or kinase
EYR02_12550	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EYR02_12550	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EYR02_12555	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EYR02_12575	COG3039	Transposase
EYR02_12585	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EYR02_12630	COG0835	chemotaxis
EYR02_12635	COG0840	transmembrane signaling receptor activity
EYR02_12665	COG2969	positive regulation of protein catabolic process
EYR02_12670	COG0625	glutathione transferase activity
EYR02_12675	COG2857	Cytochrome c1
EYR02_12680	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EYR02_12685	COG0723	plastoquinol--plastocyanin reductase activity
EYR02_12695	COG0741	lytic transglycosylase activity
EYR02_12720	COG1702	phosphate starvation-inducible protein PhoH
EYR02_12740	COG4535	Mg2 and Co2 transporter CorC
EYR02_12755	COG1012	belongs to the aldehyde dehydrogenase family
EYR02_12760	COG1177	transmembrane transport
EYR02_12765	COG1176	ABC-type spermidine putrescine transport system, permease component I
EYR02_12775	COG3842	ATPase activity
EYR02_12805	COG3039	Transposase
EYR02_12830	COG0174	glutamine synthetase
EYR02_12835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYR02_12840	COG0745	RESPONSE REGULATOR receiver
EYR02_12840	COG3706	GGDEF domain
EYR02_12845	COG0477	Major facilitator Superfamily
EYR02_12855	COG0243	molybdopterin cofactor binding
EYR02_12880	COG1121	(ABC) transporter
EYR02_12890	COG2733	membrane
EYR02_12895	COG0784	Response regulator, receiver
EYR02_12895	COG2205	protein histidine kinase activity
EYR02_12895	COG5002	protein histidine kinase activity
EYR02_12905	COG3039	Transposase
EYR02_12910	COG2902	Dehydrogenase
EYR02_12920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EYR02_12925	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EYR02_12940	COG1609	Transcriptional regulator
EYR02_12945	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EYR02_12945	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYR02_12950	COG1105	Belongs to the carbohydrate kinase PfkB family
EYR02_12955	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EYR02_12955	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EYR02_12965	COG3501	Rhs element vgr protein
EYR02_12980	COG2826	transposase and inactivated derivatives, IS30 family
EYR02_13015	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EYR02_13025	COG1862	Preprotein translocase
EYR02_13095	COG0405	Gamma-glutamyltransferase
EYR02_13100	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EYR02_13120	COG0742	ribosomal rna small subunit methyltransferase
EYR02_13125	COG0326	Molecular chaperone. Has ATPase activity
EYR02_13170	COG4206	TonB-dependent receptor
EYR02_13225	COG0531	amino acid
EYR02_13240	COG0006	proline dipeptidase activity
EYR02_13250	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EYR02_13265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYR02_13270	COG3938	Belongs to the proline racemase family
EYR02_13280	COG0552	protein localization to endoplasmic reticulum
EYR02_13295	COG1194	a g-specific adenine glycosylase
EYR02_13305	COG4191	Histidine kinase
EYR02_13305	COG0784	Response regulator, receiver
EYR02_13310	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EYR02_13335	COG3040	lipid binding
EYR02_13345	COG1960	acyl-CoA dehydrogenase activity
EYR02_13395	COG0438	transferase activity, transferring glycosyl groups
EYR02_13400	COG0438	transferase activity, transferring glycosyl groups
EYR02_13445	COG0776	regulation of translation
EYR02_13455	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EYR02_13460	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EYR02_13465	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EYR02_13470	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EYR02_13510	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EYR02_13515	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EYR02_13520	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EYR02_13525	COG3115	cell septum assembly
EYR02_13550	COG0316	Belongs to the HesB IscA family
EYR02_13585	COG0288	reversible hydration of carbon dioxide
EYR02_13610	COG3844	kynureninase activity
EYR02_13620	COG2925	Exonuclease
EYR02_13630	COG0667	Aldo Keto reductase
EYR02_13645	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EYR02_13705	COG0494	nUDIX hydrolase
EYR02_13715	COG1024	Enoyl-CoA hydratase
EYR02_13725	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EYR02_13730	COG0659	secondary active sulfate transmembrane transporter activity
EYR02_13740	COG3039	Transposase
EYR02_13760	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EYR02_13765	COG0573	inorganic phosphate transmembrane transporter activity
EYR02_13770	COG0581	inorganic phosphate transmembrane transporter activity
EYR02_13780	COG0704	Plays a role in the regulation of phosphate uptake
EYR02_13790	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EYR02_13800	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EYR02_13815	COG0557	exoribonuclease II activity
EYR02_13845	COG1960	acyl-CoA dehydrogenase activity
EYR02_13855	COG0646	methionine synthase
EYR02_13855	COG1410	methionine synthase
EYR02_13860	COG0646	methionine synthase
EYR02_13860	COG1410	methionine synthase
EYR02_13870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYR02_13910	COG0386	Belongs to the glutathione peroxidase family
EYR02_13920	COG1725	Transcriptional regulator
EYR02_13925	COG1131	(ABC) transporter
EYR02_13965	COG3039	Transposase
EYR02_13975	COG2826	transposase and inactivated derivatives, IS30 family
EYR02_14000	COG2850	peptidyl-arginine hydroxylation
EYR02_14035	COG1132	(ABC) transporter
EYR02_14065	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EYR02_14080	COG0443	Heat shock 70 kDa protein
EYR02_14095	COG0497	DNA recombination
EYR02_14105	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EYR02_14115	COG2914	Belongs to the UPF0125 (RnfH) family
EYR02_14125	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EYR02_14150	COG3039	Transposase
EYR02_14205	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EYR02_14215	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EYR02_14220	COG0174	glutamine synthetase
EYR02_14265	COG3706	GGDEF domain
EYR02_14300	COG0415	Belongs to the DNA photolyase family
EYR02_14305	COG0305	Participates in initiation and elongation during chromosome replication
EYR02_14315	COG0367	asparagine synthase
EYR02_14345	COG0084	hydrolase, TatD family'
EYR02_14350	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EYR02_14390	COG0840	transmembrane signaling receptor activity
EYR02_14405	COG3039	Transposase
EYR02_14420	COG3039	Transposase
EYR02_14450	COG0386	Belongs to the glutathione peroxidase family
EYR02_14550	COG2814	Major facilitator Superfamily
EYR02_14555	COG1566	PFAM secretion protein HlyD family protein
EYR02_14570	COG2207	Transcriptional regulator
EYR02_14600	COG4774	siderophore transport
EYR02_14610	COG0367	asparagine synthase
EYR02_14615	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EYR02_14625	COG1393	Belongs to the ArsC family
EYR02_14645	COG0024	Methionine aminopeptidase
EYR02_14710	COG0575	Belongs to the CDS family
EYR02_14715	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EYR02_14720	COG0750	zinc metalloprotease
EYR02_14735	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EYR02_14765	COG0825	malonyl-CoA metabolic process
EYR02_14840	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EYR02_14855	COG2040	homocysteine
EYR02_14860	COG0833	amino acid
EYR02_14865	COG0346	lactoylglutathione lyase activity
EYR02_14885	COG2878	Part of a membrane complex involved in electron transport
EYR02_14905	COG1595	DNA-templated transcription, initiation
EYR02_14930	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EYR02_14945	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EYR02_14950	COG0251	oxidation-reduction process
EYR02_14960	COG0392	lysyltransferase activity
EYR02_14960	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EYR02_15000	COG2814	Major facilitator Superfamily
EYR02_15005	COG1902	pentaerythritol trinitrate reductase activity
EYR02_15020	COG2824	Alkylphosphonate utilization operon protein PhnA
EYR02_15030	COG1047	Peptidyl-prolyl cis-trans
EYR02_15075	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EYR02_15090	COG1451	nucleotide metabolic process
EYR02_15110	COG0183	Belongs to the thiolase family
EYR02_15125	COG3706	GGDEF domain
EYR02_15125	COG0745	RESPONSE REGULATOR receiver
EYR02_15140	COG1793	dna ligase
EYR02_15140	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EYR02_15150	COG1793	dna ligase
EYR02_15155	COG1201	RNA secondary structure unwinding
EYR02_15175	COG1278	Cold shock
EYR02_15180	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EYR02_15195	COG3046	protein related to deoxyribodipyrimidine photolyase
EYR02_15200	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
EYR02_15205	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EYR02_15255	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EYR02_15270	COG1024	Enoyl-CoA hydratase
EYR02_15270	COG1250	3-hydroxyacyl-CoA dehydrogenase
EYR02_15290	COG1024	Enoyl-CoA hydratase
EYR02_15295	COG1960	acyl-CoA dehydrogenase activity
EYR02_15370	COG2353	YceI-like domain
EYR02_15395	COG1760	l-serine dehydratase
EYR02_15405	COG0626	cystathionine gamma-synthase activity
EYR02_15410	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EYR02_15415	COG0739	heme binding
EYR02_15425	COG1272	protein, Hemolysin III
EYR02_15455	COG0516	GMP reductase activity
EYR02_15455	COG0517	IMP dehydrogenase activity
EYR02_15460	COG0463	Glycosyl transferase, family 2
EYR02_15470	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EYR02_15480	COG4771	TonB-dependent receptor
EYR02_15485	COG1309	transcriptional regulator
EYR02_15495	COG1960	acyl-CoA dehydrogenase activity
EYR02_15540	COG0330	HflC and HflK could
EYR02_15550	COG1742	UPF0060 membrane protein
EYR02_15555	COG3956	TIGRFAM MazG family protein
EYR02_15565	COG0494	nUDIX hydrolase
EYR02_15575	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EYR02_15580	COG0837	glucose binding
EYR02_15595	COG3858	chitin binding
EYR02_15595	COG1388	LysM domain
EYR02_15615	COG1472	Belongs to the glycosyl hydrolase 3 family
EYR02_15665	COG3537	Alpha-1,2-mannosidase
EYR02_15710	COG3142	Participates in the control of copper homeostasis
EYR02_15715	COG1446	asparaginase
EYR02_15725	COG2304	oxidoreductase activity
EYR02_15755	COG0840	transmembrane signaling receptor activity
EYR02_15760	COG0835	chemotaxis
EYR02_15775	COG0189	ligase activity
EYR02_15785	COG1397	ADP-ribosylglycohydrolase
EYR02_15795	COG1199	ATP-dependent helicase activity
EYR02_15805	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EYR02_15820	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EYR02_15870	COG1643	Atp-dependent helicase
EYR02_15875	COG0783	Belongs to the Dps family
EYR02_15885	COG0514	ATP-dependent DNA helicase (RecQ)
EYR02_15900	COG3039	Transposase
EYR02_15915	COG1187	pseudouridine synthase activity
EYR02_15965	COG0602	queuosine metabolic process
EYR02_15975	COG2885	chlorophyll binding
EYR02_15980	COG0823	Involved in the tonB-independent uptake of proteins
EYR02_15990	COG0848	biopolymer transport protein
EYR02_16000	COG0824	Thioesterase
EYR02_16020	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EYR02_16045	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EYR02_16060	COG0477	Major facilitator Superfamily
EYR02_16095	COG0488	(ABC) transporter
EYR02_16125	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EYR02_16125	COG4651	solute:proton antiporter activity
EYR02_16155	COG0640	Transcriptional regulator
EYR02_16170	COG4772	TonB-dependent receptor
EYR02_16180	COG4264	IucA IucC family
EYR02_16195	COG0019	diaminopimelate decarboxylase activity
EYR02_16250	COG4206	TonB-dependent receptor
EYR02_16280	COG0542	response to heat
EYR02_16305	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EYR02_16315	COG0534	Mate efflux family protein
EYR02_16365	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EYR02_16370	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EYR02_16410	COG2172	sigma factor antagonist activity
EYR02_16415	COG1366	Belongs to the anti-sigma-factor antagonist family
EYR02_16420	COG1366	Belongs to the anti-sigma-factor antagonist family
EYR02_16430	COG0326	Molecular chaperone. Has ATPase activity
EYR02_16435	COG2207	Transcriptional regulator
EYR02_16500	COG3039	Transposase
EYR02_16525	COG3209	COG3209 Rhs family protein
EYR02_16535	COG3501	Rhs element vgr protein
EYR02_16545	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EYR02_16550	COG1845	cytochrome c oxidase, subunit III
EYR02_16555	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EYR02_16575	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EYR02_16595	COG0268	Binds directly to 16S ribosomal RNA
EYR02_16620	COG0824	Thioesterase
EYR02_16645	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EYR02_16650	COG1845	cytochrome c oxidase, subunit III
EYR02_16655	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EYR02_16675	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EYR02_16690	COG0728	peptidoglycan biosynthetic process
EYR02_16695	COG0268	Binds directly to 16S ribosomal RNA
EYR02_16715	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EYR02_16720	COG0824	Thioesterase
EYR02_16735	COG1946	Acyl-CoA thioesterase
EYR02_16745	COG1595	DNA-templated transcription, initiation
EYR02_16800	COG1877	trehalose-phosphatase activity
EYR02_16805	COG3387	PFAM Glycoside hydrolase 15-related
EYR02_16845	COG0564	pseudouridine synthase activity
EYR02_16850	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EYR02_16855	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EYR02_16855	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EYR02_16870	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EYR02_16915	COG2194	sulfuric ester hydrolase activity
EYR02_16920	COG4969	Belongs to the N-Me-Phe pilin family
EYR02_16930	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EYR02_16935	COG0237	dephospho-CoA kinase activity
EYR02_16940	COG2205	protein histidine kinase activity
EYR02_16945	COG0745	RESPONSE REGULATOR receiver
EYR02_16965	COG3039	Transposase
EYR02_16990	COG3039	Transposase
EYR02_17020	COG3039	Transposase
EYR02_17060	COG0471	metal ion transport
EYR02_17060	COG3273	potassium ion transport
EYR02_17090	COG1970	mechanosensitive ion channel activity
EYR02_17125	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EYR02_17140	COG0308	aminopeptidase N
EYR02_17145	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EYR02_17155	COG0529	Catalyzes the synthesis of activated sulfate
EYR02_17155	COG2895	sulfate adenylyltransferase (ATP) activity
EYR02_17165	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EYR02_17195	COG0784	Response regulator, receiver
EYR02_17195	COG2198	Histidine kinase
EYR02_17195	COG2205	protein histidine kinase activity
EYR02_17235	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EYR02_17240	COG3588	fructose-bisphosphate aldolase
EYR02_17245	COG0469	pyruvate kinase activity
EYR02_17270	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EYR02_17280	COG3453	Protein conserved in bacteria
EYR02_17280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EYR02_17285	COG0725	ABC transporter, periplasmic molybdate-binding protein
EYR02_17290	COG4149	molybdate abc transporter
EYR02_17295	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EYR02_17315	COG0642	Histidine kinase
EYR02_17320	COG0745	RESPONSE REGULATOR receiver
EYR02_17330	COG1028	Short-chain dehydrogenase reductase Sdr
EYR02_17340	COG1022	Amp-dependent synthetase and ligase
EYR02_17365	COG1376	ErfK ybiS ycfS ynhG family protein
EYR02_17370	COG0739	heme binding
EYR02_17385	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EYR02_17390	COG1301	dicarboxylic acid transport
EYR02_17410	COG2304	oxidoreductase activity
EYR02_17430	COG0714	Associated with various cellular activities
EYR02_17465	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EYR02_17490	COG0254	rRNA binding
EYR02_17500	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EYR02_17510	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EYR02_17515	COG1758	RNA polymerase activity
EYR02_17530	COG1561	YicC-like family, N-terminal region
EYR02_17550	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EYR02_17580	COG0006	proline dipeptidase activity
EYR02_17605	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EYR02_17625	COG2912	Transglutaminase-like superfamily
EYR02_17630	COG1773	rubredoxin
EYR02_17635	COG0352	thiamine-phosphate diphosphorylase activity
EYR02_17660	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
EYR02_17705	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EYR02_17730	COG0671	phosphoesterase, PA-phosphatase related
EYR02_17745	COG3781	membrane
EYR02_17755	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EYR02_17770	COG3039	Transposase
EYR02_17785	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
EYR02_17795	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EYR02_17820	COG3710	Transcriptional regulator
EYR02_17865	COG2226	methyltransferase
EYR02_17895	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EYR02_17900	COG1538	Outer membrane efflux protein
EYR02_17905	COG1519	Transferase
EYR02_17910	COG1560	Kdo2-lipid A biosynthetic process
EYR02_17945	COG2826	transposase and inactivated derivatives, IS30 family
EYR02_17985	COG0280	phosphate acetyltransferase
EYR02_17985	COG0281	malic enzyme
EYR02_18005	COG4191	Histidine kinase
EYR02_18020	COG0583	DNA-binding transcription factor activity
EYR02_18040	COG2197	response regulator
EYR02_18050	COG0642	Histidine kinase
EYR02_18070	COG2851	Citrate transporter
EYR02_18075	COG1028	Short-chain dehydrogenase reductase Sdr
EYR02_18085	COG1609	Transcriptional regulator
EYR02_18090	COG2211	Major facilitator Superfamily
EYR02_18120	COG0436	Aminotransferase
EYR02_18140	COG0726	polysaccharide deacetylase
EYR02_18145	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EYR02_18165	COG0402	S-adenosylhomocysteine deaminase activity
EYR02_18215	COG0242	peptide deformylase activity
EYR02_18220	COG3039	Transposase
EYR02_18250	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EYR02_18310	COG2188	Transcriptional regulator
EYR02_18325	COG1450	Type ii and iii secretion system protein
EYR02_18340	COG3166	PFAM Fimbrial assembly family protein
EYR02_18345	COG3156	type II secretion system protein K
EYR02_18350	COG4795	General secretion pathway protein
EYR02_18355	COG2165	general secretion pathway protein
EYR02_18360	COG4970	Tfp pilus assembly protein FimT
EYR02_18365	COG2165	general secretion pathway protein
EYR02_18370	COG1459	type II secretion system
EYR02_18380	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EYR02_18385	COG1404	Belongs to the peptidase S8 family
EYR02_18390	COG5295	Hep Hag repeat protein
EYR02_18400	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EYR02_18400	COG0047	phosphoribosylformylglycinamidine synthase activity
EYR02_18410	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EYR02_18415	COG4974	Belongs to the 'phage' integrase family
EYR02_18430	COG0795	lipopolysaccharide-transporting ATPase activity
EYR02_18465	COG0525	valine-tRNA ligase activity
EYR02_18495	COG2826	transposase and inactivated derivatives, IS30 family
EYR02_18505	COG2826	transposase and inactivated derivatives, IS30 family
EYR02_18530	COG1183	phosphatidylcholine synthase activity
EYR02_18555	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EYR02_18560	COG1127	ABC transporter
EYR02_18565	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EYR02_18565	COG3218	ABC-type transport auxiliary lipoprotein component
EYR02_18610	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EYR02_18615	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
EYR02_18615	COG0662	Cupin 2, conserved barrel domain protein
EYR02_18645	COG2086	electron transfer activity
EYR02_18730	COG0626	cystathionine gamma-synthase activity
EYR02_18760	COG0625	glutathione transferase activity
EYR02_18775	COG0513	Belongs to the DEAD box helicase family
EYR02_18785	COG0720	synthase
EYR02_18800	COG1956	GAF domain-containing protein
EYR02_18810	COG3039	Transposase
EYR02_18815	COG0546	phosphoglycolate phosphatase activity
EYR02_18845	COG0339	signal peptide processing
EYR02_18895	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EYR02_18975	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EYR02_18985	COG0356	it plays a direct role in the translocation of protons across the membrane
EYR02_19005	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EYR02_19015	COG0508	dehydrogenase complex catalyzes the overall conversion of
EYR02_19050	COG2011	ABC-type metal ion transport system permease component
EYR02_19060	COG0697	spore germination
EYR02_19095	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EYR02_19105	COG2813	Specifically methylates the guanine in position
EYR02_19135	COG2202	Pas domain
EYR02_19135	COG2205	protein histidine kinase activity
EYR02_19160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYR02_19225	COG0745	RESPONSE REGULATOR receiver
EYR02_19240	COG1404	Belongs to the peptidase S8 family
EYR02_19255	COG0842	Transport permease protein
EYR02_19260	COG1131	(ABC) transporter
EYR02_19265	COG0025	NhaP-type Na H and K H
EYR02_19275	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EYR02_19285	COG1573	uracil-dna glycosylase
EYR02_19295	COG3384	dioxygenase
EYR02_19310	COG0667	Aldo Keto reductase
EYR02_19320	COG3590	peptidase
EYR02_19340	COG0531	amino acid
EYR02_19365	COG3685	Protein conserved in bacteria
EYR02_19370	COG3546	catalase activity
EYR02_19395	COG3039	Transposase
EYR02_19425	COG1271	oxidase subunit
EYR02_19430	COG1294	oxidase, subunit
EYR02_19460	COG1063	alcohol dehydrogenase
EYR02_19565	COG1473	amidohydrolase
EYR02_19570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EYR02_19575	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EYR02_19600	COG5383	Protein conserved in bacteria
EYR02_19655	COG3023	N-Acetylmuramoyl-L-alanine amidase
EYR02_19665	COG4948	Mandelate Racemase Muconate Lactonizing
EYR02_19695	COG0531	amino acid
EYR02_19715	COG4682	membrane
EYR02_19720	COG2133	pyrroloquinoline quinone binding
EYR02_19740	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EYR02_19750	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EYR02_19755	COG1610	YqeY-like protein
EYR02_19775	COG1295	ribonuclease BN
EYR02_19780	COG0358	DNA primase activity
EYR02_19850	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
EYR02_19865	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EYR02_19925	COG0739	heme binding
EYR02_19940	COG2211	Major facilitator Superfamily
EYR02_19945	COG0708	Exodeoxyribonuclease III
EYR02_19960	COG1192	Involved in chromosome partitioning
EYR02_19965	COG1475	DNA binding
EYR02_19985	COG0463	Glycosyl transferase, family 2
EYR02_20010	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EYR02_20035	COG4221	oxidoreductase activity
EYR02_20075	COG1166	arginine decarboxylase activity
EYR02_20125	COG0606	chelatase, subunit chli
EYR02_20150	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EYR02_20170	COG3039	Transposase
EYR02_20230	COG1090	epimerase
EYR02_20240	COG0642	Histidine kinase
EYR02_20255	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EYR02_20290	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EYR02_20300	COG1595	DNA-templated transcription, initiation
EYR02_20305	COG0753	catalase activity
EYR02_20330	COG0697	spore germination
EYR02_20355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EYR02_20360	COG0180	Tryptophanyl-tRNA synthetase
EYR02_20365	COG3237	CsbD-like
EYR02_20420	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EYR02_20420	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EYR02_20430	COG3228	Belongs to the MtfA family
EYR02_20445	COG2205	protein histidine kinase activity
EYR02_20450	COG0745	RESPONSE REGULATOR receiver
EYR02_20460	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EYR02_20515	COG3039	Transposase
EYR02_20520	COG1566	PFAM secretion protein HlyD family protein
EYR02_20535	COG1199	ATP-dependent helicase activity
EYR02_20580	COG0583	DNA-binding transcription factor activity
EYR02_20640	COG2826	transposase and inactivated derivatives, IS30 family
EYR02_20675	COG4555	ABC transporter
EYR02_20685	COG1476	TRANSCRIPTIONal
EYR02_20705	COG1230	cation diffusion facilitator family transporter
EYR02_20710	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EYR02_20715	COG1131	(ABC) transporter
EYR02_20720	COG0842	Transport permease protein
EYR02_20730	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EYR02_20785	COG2951	lytic endotransglycosylase activity
EYR02_20805	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EYR02_20815	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EYR02_20830	COG1042	CoA-binding domain protein
EYR02_20830	COG0045	succinate-CoA ligase (ADP-forming) activity
EYR02_20830	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EYR02_20840	COG2239	Acts as a magnesium transporter
EYR02_20865	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EYR02_20870	COG3387	PFAM Glycoside hydrolase 15-related
EYR02_20885	COG3100	YcgL domain-containing protein
EYR02_20890	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EYR02_20900	COG0463	Glycosyl transferase, family 2
EYR02_20915	COG1028	Short-chain dehydrogenase reductase Sdr
EYR02_20945	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EYR02_20960	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EYR02_21090	COG0210	DNA helicase
EYR02_21110	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EYR02_21125	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EYR02_21140	COG2159	amidohydrolase
EYR02_21145	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EYR02_21150	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EYR02_21170	COG0357	Ribosomal RNA small subunit methyltransferase G
EYR02_21175	COG3540	Alkaline phosphatase
EYR02_21185	COG2091	lysine biosynthetic process via aminoadipic acid
EYR02_21200	COG0708	Exodeoxyribonuclease III
EYR02_21215	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EYR02_21220	COG3162	membrane
EYR02_21275	COG1028	Short-chain dehydrogenase reductase Sdr
EYR02_21280	COG0179	Fumarylacetoacetate (FAA) hydrolase
EYR02_21290	COG4948	Mandelate Racemase Muconate Lactonizing
EYR02_21300	COG3039	Transposase
EYR02_21305	COG3254	rhamnose metabolic process
EYR02_21310	COG0738	Major facilitator superfamily
EYR02_21315	COG1414	Transcriptional regulator
EYR02_21325	COG2205	protein histidine kinase activity
EYR02_21335	COG3459	Glycosyltransferase 36 associated
EYR02_21340	COG2211	Major facilitator Superfamily
EYR02_21345	COG3265	gluconokinase activity
EYR02_21350	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EYR02_21380	COG3039	Transposase
EYR02_21390	COG3039	Transposase
EYR02_21395	COG2911	Protein conserved in bacteria
EYR02_21400	COG0729	surface antigen
EYR02_21405	COG4771	TonB-dependent receptor
EYR02_21410	COG0457	Tetratricopeptide repeat
EYR02_21425	COG0752	glycyl-tRNA synthetase alpha subunit
EYR02_21430	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EYR02_21445	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EYR02_21445	COG0519	Catalyzes the synthesis of GMP from XMP
EYR02_21455	COG0805	protein transport
EYR02_21460	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EYR02_21465	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EYR02_21475	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EYR02_21505	COG2974	May be involved in recombination
EYR02_21510	COG0037	tRNA processing
EYR02_21530	COG3661	Belongs to the glycosyl hydrolase 67 family
EYR02_21540	COG4948	Mandelate Racemase Muconate Lactonizing
EYR02_21550	COG1472	Belongs to the glycosyl hydrolase 3 family
EYR02_21555	COG0246	Mannitol dehydrogenase
EYR02_21590	COG2826	transposase and inactivated derivatives, IS30 family
EYR02_21615	COG3693	PFAM glycoside hydrolase, family 10
EYR02_21640	COG2211	Major facilitator Superfamily
EYR02_21655	COG3039	Transposase
EYR02_21685	COG2937	Belongs to the GPAT DAPAT family
EYR02_21735	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EYR02_21755	COG0210	DNA helicase
EYR02_21770	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
EYR02_21835	COG0676	glucose-6-phosphate 1-epimerase activity
EYR02_21850	COG0730	response to heat
EYR02_21885	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EYR02_21890	COG0302	gtp cyclohydrolase
EYR02_21920	COG2826	transposase and inactivated derivatives, IS30 family
EYR02_21930	COG0477	Major facilitator Superfamily
EYR02_21945	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EYR02_21990	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYR02_22050	COG3237	CsbD-like
EYR02_22085	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYR02_22140	COG4772	TonB-dependent receptor
EYR02_22150	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EYR02_22180	COG3039	Transposase
EYR02_22235	COG0564	pseudouridine synthase activity
EYR02_22250	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EYR02_22285	COG3039	Transposase
EYR02_22310	COG2826	transposase and inactivated derivatives, IS30 family
EYR02_22375	COG1074	ATP-dependent DNA helicase activity
EYR02_22380	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EYR02_22385	COG1116	anion transmembrane transporter activity
EYR02_22395	COG3039	Transposase
EYR02_22400	COG3039	Transposase
EYR02_22410	COG1136	(ABC) transporter
EYR02_22430	COG1127	ABC transporter
EYR02_22435	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EYR02_22440	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EYR02_22455	COG2853	Lipoprotein
EYR02_22475	COG0386	Belongs to the glutathione peroxidase family
EYR02_22485	COG1322	Protein conserved in bacteria
EYR02_22490	COG3039	Transposase
EYR02_22515	COG1929	Belongs to the glycerate kinase type-1 family
EYR02_22520	COG2271	Major facilitator Superfamily
EYR02_22535	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EYR02_22545	COG0861	Integral membrane protein TerC family
EYR02_22555	COG0584	glycerophosphoryl diester phosphodiesterase
EYR02_22565	COG0671	phosphoesterase, PA-phosphatase related
EYR02_22570	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EYR02_22575	COG0726	polysaccharide deacetylase
EYR02_22590	COG0230	Belongs to the bacterial ribosomal protein bL34 family