locus-tag	class	description
LNP58_00040	COG2353	YceI-like domain
LNP58_00050	COG2353	YceI-like domain
LNP58_00065	COG1760	l-serine dehydratase
LNP58_00075	COG0626	cystathionine gamma-synthase activity
LNP58_00080	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LNP58_00085	COG0739	heme binding
LNP58_00095	COG1272	protein, Hemolysin III
LNP58_00120	COG0463	Glycosyl transferase, family 2
LNP58_00130	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LNP58_00140	COG4771	TonB-dependent receptor
LNP58_00145	COG1309	transcriptional regulator
LNP58_00155	COG1960	acyl-CoA dehydrogenase activity
LNP58_00190	COG0509	glycine decarboxylation via glycine cleavage system
LNP58_00205	COG0330	HflC and HflK could
LNP58_00220	COG3956	TIGRFAM MazG family protein
LNP58_00230	COG0494	nUDIX hydrolase
LNP58_00240	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LNP58_00245	COG0837	glucose binding
LNP58_00260	COG1388	LysM domain
LNP58_00260	COG3858	chitin binding
LNP58_00270	COG3525	Glycosyl hydrolase, family 20, catalytic domain
LNP58_00280	COG1472	Belongs to the glycosyl hydrolase 3 family
LNP58_00360	COG3537	Alpha-1,2-mannosidase
LNP58_00410	COG3142	Participates in the control of copper homeostasis
LNP58_00415	COG1446	asparaginase
LNP58_00425	COG2304	oxidoreductase activity
LNP58_00430	COG2304	oxidoreductase activity
LNP58_00455	COG2198	Histidine kinase
LNP58_00455	COG0784	Response regulator, receiver
LNP58_00455	COG0643	Histidine kinase
LNP58_00460	COG0840	transmembrane signaling receptor activity
LNP58_00465	COG0835	chemotaxis
LNP58_00480	COG0189	ligase activity
LNP58_00490	COG1397	ADP-ribosylglycohydrolase
LNP58_00500	COG1199	ATP-dependent helicase activity
LNP58_00510	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LNP58_00515	COG1215	transferase activity, transferring glycosyl groups
LNP58_00525	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LNP58_00580	COG1643	Atp-dependent helicase
LNP58_00585	COG0783	Belongs to the Dps family
LNP58_00590	COG0514	ATP-dependent DNA helicase (RecQ)
LNP58_00615	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LNP58_00660	COG4695	Portal protein
LNP58_00705	COG3179	chitinase
LNP58_00735	COG3039	Transposase
LNP58_00895	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LNP58_00950	COG1187	pseudouridine synthase activity
LNP58_00955	COG0602	queuosine metabolic process
LNP58_00965	COG2885	chlorophyll binding
LNP58_00980	COG0848	biopolymer transport protein
LNP58_00990	COG0824	Thioesterase
LNP58_00995	COG2255	four-way junction helicase activity
LNP58_01005	COG0632	four-way junction helicase activity
LNP58_01110	COG3209	COG3209 Rhs family protein
LNP58_01130	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LNP58_01135	COG1845	cytochrome c oxidase, subunit III
LNP58_01140	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LNP58_01155	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LNP58_01160	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LNP58_01170	COG0196	riboflavin kinase activity
LNP58_01175	COG0728	peptidoglycan biosynthetic process
LNP58_01180	COG0268	Binds directly to 16S ribosomal RNA
LNP58_01185	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LNP58_01190	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LNP58_01200	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LNP58_01205	COG0824	Thioesterase
LNP58_01220	COG1946	Acyl-CoA thioesterase
LNP58_01250	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
LNP58_01290	COG1877	trehalose-phosphatase activity
LNP58_01295	COG3387	PFAM Glycoside hydrolase 15-related
LNP58_01320	COG0564	pseudouridine synthase activity
LNP58_01325	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LNP58_01330	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LNP58_01330	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LNP58_01345	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LNP58_01350	COG0045	succinate-CoA ligase (ADP-forming) activity
LNP58_01375	COG2184	nucleotidyltransferase activity
LNP58_01395	COG2194	sulfuric ester hydrolase activity
LNP58_01400	COG4969	Belongs to the N-Me-Phe pilin family
LNP58_01410	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LNP58_01445	COG3039	Transposase
LNP58_01450	COG3039	Transposase
LNP58_01475	COG3039	Transposase
LNP58_01505	COG1132	(ABC) transporter
LNP58_01535	COG0745	RESPONSE REGULATOR receiver
LNP58_01540	COG5000	phosphorelay sensor kinase activity
LNP58_01540	COG5002	protein histidine kinase activity
LNP58_01545	COG0475	glutathione-regulated potassium exporter activity
LNP58_01555	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LNP58_01575	COG1187	pseudouridine synthase activity
LNP58_01580	COG5001	Diguanylate cyclase
LNP58_01580	COG5002	protein histidine kinase activity
LNP58_01700	COG0415	Belongs to the DNA photolyase family
LNP58_01705	COG0305	Participates in initiation and elongation during chromosome replication
LNP58_01715	COG0367	asparagine synthase
LNP58_01730	COG1960	acyl-CoA dehydrogenase activity
LNP58_01745	COG0084	hydrolase, TatD family'
LNP58_01750	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LNP58_01810	COG0735	belongs to the Fur family
LNP58_01815	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LNP58_01910	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LNP58_01920	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LNP58_01935	COG2198	Histidine kinase
LNP58_01935	COG0643	Histidine kinase
LNP58_01940	COG0840	transmembrane signaling receptor activity
LNP58_01945	COG0835	chemotaxis
LNP58_01950	COG2202	Pas domain
LNP58_01950	COG2200	EAL domain
LNP58_01950	COG2199	diguanylate cyclase activity
LNP58_01955	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LNP58_01970	COG3590	peptidase
LNP58_01990	COG1515	deoxyribonuclease V activity
LNP58_02000	COG1741	Belongs to the pirin family
LNP58_02050	COG3039	Transposase
LNP58_02095	COG3039	Transposase
LNP58_02130	COG1741	Belongs to the pirin family
LNP58_02135	COG1966	Carbon starvation protein
LNP58_02140	COG2879	small protein
LNP58_02175	COG2203	Gaf domain
LNP58_02175	COG3706	GGDEF domain
LNP58_02175	COG4251	negative regulation of phosphorylation
LNP58_02175	COG5001	Diguanylate cyclase
LNP58_02180	COG0629	single-stranded DNA binding
LNP58_02185	COG0142	geranyltranstransferase activity
LNP58_02210	COG0527	aspartate kinase activity
LNP58_02220	COG0384	phenazine biosynthesis protein PhzF
LNP58_02230	COG1764	response to oxidative stress
LNP58_02245	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LNP58_02250	COG1678	Uncharacterized ACR, COG1678
LNP58_02260	COG0519	Catalyzes the synthesis of GMP from XMP
LNP58_02290	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LNP58_02350	COG1959	2 iron, 2 sulfur cluster binding
LNP58_02355	COG0719	Fe-S assembly protein
LNP58_02360	COG0396	ATPase activity
LNP58_02365	COG0719	Fe-S assembly protein
LNP58_02370	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LNP58_02380	COG2146	nitrite reductase [NAD(P)H] activity
LNP58_02415	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LNP58_02430	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LNP58_02440	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
LNP58_02445	COG0174	glutamine synthetase
LNP58_02450	COG3328	transposase activity
LNP58_02475	COG0326	Molecular chaperone. Has ATPase activity
LNP58_02480	COG2207	Transcriptional regulator
LNP58_02510	COG0657	acetylesterase activity
LNP58_02510	COG2755	lipolytic protein G-D-S-L family
LNP58_02535	COG0488	(ABC) transporter
LNP58_02570	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LNP58_02570	COG4651	solute:proton antiporter activity
LNP58_02585	COG4772	TonB-dependent receptor
LNP58_02595	COG4264	IucA IucC family
LNP58_02600	COG2814	Major facilitator Superfamily
LNP58_02610	COG0019	diaminopimelate decarboxylase activity
LNP58_02675	COG4206	TonB-dependent receptor
LNP58_02710	COG0542	response to heat
LNP58_02745	COG0534	Mate efflux family protein
LNP58_02760	COG0336	Belongs to the RNA methyltransferase TrmD family
LNP58_02765	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LNP58_02770	COG0228	four-way junction DNA binding
LNP58_02790	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LNP58_02800	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LNP58_02840	COG1555	photosystem II stabilization
LNP58_02845	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LNP58_02860	COG3178	'Phosphotransferase
LNP58_02865	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LNP58_02875	COG0628	permease
LNP58_02885	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LNP58_02900	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LNP58_02925	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LNP58_02930	COG0271	Belongs to the BolA IbaG family
LNP58_02940	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LNP58_02950	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
LNP58_02955	COG1137	ATPase activity
LNP58_02970	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LNP58_02975	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LNP58_02980	COG1660	Displays ATPase and GTPase activities
LNP58_02990	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LNP58_02995	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LNP58_03000	COG2239	Acts as a magnesium transporter
LNP58_03010	COG1294	oxidase, subunit
LNP58_03015	COG1271	oxidase subunit
LNP58_03030	COG1113	amino acid transport
LNP58_03045	COG2197	response regulator
LNP58_03050	COG0531	amino acid
LNP58_03110	COG0754	glutathionylspermidine amidase activity
LNP58_03135	COG1842	Phage shock protein A
LNP58_03150	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LNP58_03155	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LNP58_03165	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LNP58_03195	COG2201	protein-glutamate methylesterase activity
LNP58_03245	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LNP58_03290	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LNP58_03295	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LNP58_03340	COG0745	RESPONSE REGULATOR receiver
LNP58_03345	COG2205	protein histidine kinase activity
LNP58_03365	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LNP58_03395	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LNP58_03395	COG3453	Protein conserved in bacteria
LNP58_03400	COG0725	ABC transporter, periplasmic molybdate-binding protein
LNP58_03405	COG4149	molybdate abc transporter
LNP58_03410	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
LNP58_03430	COG0642	Histidine kinase
LNP58_03445	COG1028	Short-chain dehydrogenase reductase Sdr
LNP58_03455	COG1022	Amp-dependent synthetase and ligase
LNP58_03480	COG1376	ErfK ybiS ycfS ynhG family protein
LNP58_03485	COG0739	heme binding
LNP58_03495	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LNP58_03500	COG1301	dicarboxylic acid transport
LNP58_03520	COG2304	oxidoreductase activity
LNP58_03540	COG0714	Associated with various cellular activities
LNP58_03590	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LNP58_03620	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LNP58_03630	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LNP58_03655	COG1561	YicC-like family, N-terminal region
LNP58_03660	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LNP58_03675	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LNP58_03715	COG0006	proline dipeptidase activity
LNP58_03740	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LNP58_03760	COG2912	Transglutaminase-like superfamily
LNP58_03765	COG1773	rubredoxin
LNP58_03770	COG0352	thiamine-phosphate diphosphorylase activity
LNP58_03800	COG0281	malic enzyme
LNP58_03800	COG0280	phosphate acetyltransferase
LNP58_03820	COG4191	Histidine kinase
LNP58_03835	COG0583	DNA-binding transcription factor activity
LNP58_03855	COG2197	response regulator
LNP58_03865	COG0642	Histidine kinase
LNP58_03880	COG2851	Citrate transporter
LNP58_03885	COG1028	Short-chain dehydrogenase reductase Sdr
LNP58_03890	COG1609	Transcriptional regulator
LNP58_03900	COG2211	Major facilitator Superfamily
LNP58_03950	COG0726	polysaccharide deacetylase
LNP58_03955	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LNP58_03980	COG3039	Transposase
LNP58_04025	COG0242	peptide deformylase activity
LNP58_04045	COG0714	Associated with various cellular activities
LNP58_04065	COG0537	adenosine 5'-monophosphoramidase activity
LNP58_04095	COG0314	molybdopterin synthase activity
LNP58_04100	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LNP58_04105	COG0315	cyclic pyranopterin monophosphate synthase activity
LNP58_04115	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LNP58_04120	COG1234	tRNA 3'-trailer cleavage
LNP58_04125	COG3642	lipopolysaccharide core region biosynthetic process
LNP58_04130	COG0859	PFAM glycosyl transferase family 9
LNP58_04140	COG0582	viral genome integration into host DNA
LNP58_04200	COG0631	protein serine/threonine phosphatase activity
LNP58_04210	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LNP58_04235	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LNP58_04275	COG0544	peptidyl-prolyl cis-trans isomerase activity
LNP58_04330	COG0473	3-isopropylmalate dehydrogenase activity
LNP58_04355	COG0584	glycerophosphoryl diester phosphodiesterase
LNP58_04375	COG3039	Transposase
LNP58_04505	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
LNP58_04525	COG1217	gtp-binding protein TYPA
LNP58_04530	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LNP58_04540	COG0625	glutathione transferase activity
LNP58_04555	COG3781	membrane
LNP58_04565	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LNP58_04595	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
LNP58_04615	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LNP58_04640	COG3710	Transcriptional regulator
LNP58_04645	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LNP58_04655	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LNP58_04690	COG0066	3-isopropylmalate dehydratase activity
LNP58_04695	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LNP58_04715	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LNP58_04720	COG1538	Outer membrane efflux protein
LNP58_04725	COG1519	Transferase
LNP58_04730	COG1560	Kdo2-lipid A biosynthetic process
LNP58_04750	COG3039	Transposase
LNP58_04785	COG0308	aminopeptidase N
LNP58_04800	COG0330	HflC and HflK could
LNP58_04805	COG0330	HflC and HflK could
LNP58_04825	COG0678	peroxiredoxin activity
LNP58_04835	COG2826	transposase and inactivated derivatives, IS30 family
LNP58_04865	COG3039	Transposase
LNP58_04890	COG3039	Transposase
LNP58_04920	COG3829	transcription factor binding
LNP58_04955	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LNP58_04960	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LNP58_04970	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LNP58_04975	COG1028	Short-chain dehydrogenase reductase Sdr
LNP58_05000	COG1399	metal-binding, possibly nucleic acid-binding protein
LNP58_05040	COG1518	maintenance of DNA repeat elements
LNP58_05045	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LNP58_05090	COG2188	Transcriptional regulator
LNP58_05105	COG1450	Type ii and iii secretion system protein
LNP58_05120	COG3166	PFAM Fimbrial assembly family protein
LNP58_05125	COG3156	type II secretion system protein K
LNP58_05130	COG4795	General secretion pathway protein
LNP58_05135	COG2165	general secretion pathway protein
LNP58_05140	COG4970	Tfp pilus assembly protein FimT
LNP58_05145	COG2165	general secretion pathway protein
LNP58_05150	COG1459	type II secretion system
LNP58_05160	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LNP58_05180	COG5295	Hep Hag repeat protein
LNP58_05185	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LNP58_05185	COG0047	phosphoribosylformylglycinamidine synthase activity
LNP58_05190	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LNP58_05195	COG4974	Belongs to the 'phage' integrase family
LNP58_05210	COG0795	lipopolysaccharide-transporting ATPase activity
LNP58_05220	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LNP58_05235	COG0525	valine-tRNA ligase activity
LNP58_05275	COG3039	Transposase
LNP58_05300	COG3039	Transposase
LNP58_05325	COG1183	phosphatidylcholine synthase activity
LNP58_05335	COG0442	prolyl-tRNA aminoacylation
LNP58_05350	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LNP58_05355	COG1127	ABC transporter
LNP58_05360	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LNP58_05360	COG3218	ABC-type transport auxiliary lipoprotein component
LNP58_05395	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LNP58_05400	COG0662	Cupin 2, conserved barrel domain protein
LNP58_05400	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
LNP58_05425	COG2086	electron transfer activity
LNP58_05450	COG3328	transposase activity
LNP58_05490	COG0626	cystathionine gamma-synthase activity
LNP58_05530	COG0513	Belongs to the DEAD box helicase family
LNP58_05535	COG0720	synthase
LNP58_05545	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LNP58_05550	COG1956	GAF domain-containing protein
LNP58_05585	COG0339	signal peptide processing
LNP58_05640	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LNP58_05645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LNP58_05695	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LNP58_05700	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LNP58_05705	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LNP58_05710	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LNP58_05720	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LNP58_05730	COG0356	it plays a direct role in the translocation of protons across the membrane
LNP58_05750	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LNP58_05760	COG0508	dehydrogenase complex catalyzes the overall conversion of
LNP58_05790	COG2011	ABC-type metal ion transport system permease component
LNP58_05800	COG0697	spore germination
LNP58_05840	COG1187	pseudouridine synthase activity
LNP58_05845	COG2813	Specifically methylates the guanine in position
LNP58_05875	COG2205	protein histidine kinase activity
LNP58_05875	COG2202	Pas domain
LNP58_05900	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LNP58_05950	COG0745	RESPONSE REGULATOR receiver
LNP58_05965	COG1404	Belongs to the peptidase S8 family
LNP58_05985	COG0842	Transport permease protein
LNP58_05990	COG1131	(ABC) transporter
LNP58_05995	COG0025	NhaP-type Na H and K H
LNP58_06005	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
LNP58_06015	COG1573	uracil-dna glycosylase
LNP58_06025	COG3384	dioxygenase
LNP58_06040	COG0667	Aldo Keto reductase
LNP58_06055	COG3590	peptidase
LNP58_06075	COG0531	amino acid
LNP58_06090	COG2972	Histidine kinase
LNP58_06115	COG2204	response regulator
LNP58_06125	COG1271	oxidase subunit
LNP58_06130	COG1294	oxidase, subunit
LNP58_06285	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LNP58_06295	COG1560	Kdo2-lipid A biosynthetic process
LNP58_06345	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LNP58_06345	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LNP58_06350	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LNP58_06355	COG0242	peptide deformylase activity
LNP58_06360	COG1652	LysM domain
LNP58_06365	COG0758	DNA mediated transformation
LNP58_06370	COG2922	Belongs to the Smg family
LNP58_06385	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LNP58_06385	COG1754	DNA topoisomerase type I activity
LNP58_06390	COG0009	L-threonylcarbamoyladenylate synthase
LNP58_06405	COG1028	Short-chain dehydrogenase reductase Sdr
LNP58_06415	COG0616	signal peptide processing
LNP58_06420	COG0534	Mate efflux family protein
LNP58_06440	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LNP58_06475	COG1324	tolerance protein
LNP58_06485	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LNP58_06490	COG0511	ligase activity, forming carbon-carbon bonds
LNP58_06500	COG0439	Biotin carboxylase
LNP58_06540	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
LNP58_06575	COG0419	ATPase involved in DNA repair
LNP58_06585	COG0151	Belongs to the GarS family
LNP58_06590	COG0577	efflux transmembrane transporter activity
LNP58_06590	COG1136	(ABC) transporter
LNP58_06600	COG1289	transmembrane transporter activity
LNP58_06615	COG2814	Major facilitator Superfamily
LNP58_06630	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
LNP58_06670	COG0745	RESPONSE REGULATOR receiver
LNP58_06715	COG0739	heme binding
LNP58_06730	COG2211	Major facilitator Superfamily
LNP58_06740	COG0708	Exodeoxyribonuclease III
LNP58_06755	COG1192	Involved in chromosome partitioning
LNP58_06760	COG1475	DNA binding
LNP58_06775	COG0463	Glycosyl transferase, family 2
LNP58_06800	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LNP58_06805	COG2003	Belongs to the UPF0758 family
LNP58_06810	COG0018	arginyl-trna synthetase
LNP58_06825	COG4221	oxidoreductase activity
LNP58_06850	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LNP58_06855	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LNP58_06860	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LNP58_06870	COG3485	protocatechuate 3,4-dioxygenase
LNP58_06875	COG3485	protocatechuate 3,4-dioxygenase
LNP58_06910	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LNP58_06915	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LNP58_06925	COG0045	succinate-CoA ligase (ADP-forming) activity
LNP58_06925	COG1042	CoA-binding domain protein
LNP58_06925	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LNP58_06935	COG2239	Acts as a magnesium transporter
LNP58_06950	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LNP58_06955	COG3387	PFAM Glycoside hydrolase 15-related
LNP58_06970	COG3100	YcgL domain-containing protein
LNP58_06975	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LNP58_06985	COG0463	Glycosyl transferase, family 2
LNP58_07000	COG1028	Short-chain dehydrogenase reductase Sdr
LNP58_07010	COG0156	8-amino-7-oxononanoate synthase activity
LNP58_07015	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LNP58_07020	COG1040	competence protein
LNP58_07025	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LNP58_07035	COG0628	permease
LNP58_07045	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LNP58_07055	COG1595	DNA-templated transcription, initiation
LNP58_07060	COG0753	catalase activity
LNP58_07105	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LNP58_07110	COG0180	Tryptophanyl-tRNA synthetase
LNP58_07115	COG3237	CsbD-like
LNP58_07150	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LNP58_07165	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LNP58_07170	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
LNP58_07170	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
LNP58_07180	COG3228	Belongs to the MtfA family
LNP58_07210	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LNP58_07250	COG1199	ATP-dependent helicase activity
LNP58_07290	COG0583	DNA-binding transcription factor activity
LNP58_07335	COG0625	glutathione transferase activity
LNP58_07370	COG4555	ABC transporter
LNP58_07380	COG1476	TRANSCRIPTIONal
LNP58_07405	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LNP58_07410	COG1131	(ABC) transporter
LNP58_07415	COG0842	Transport permease protein
LNP58_07425	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LNP58_07505	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LNP58_07515	COG0564	pseudouridine synthase activity
LNP58_07545	COG0339	signal peptide processing
LNP58_07580	COG3254	rhamnose metabolic process
LNP58_07585	COG0738	Major facilitator superfamily
LNP58_07590	COG1414	Transcriptional regulator
LNP58_07600	COG2205	protein histidine kinase activity
LNP58_07610	COG3459	Glycosyltransferase 36 associated
LNP58_07615	COG2211	Major facilitator Superfamily
LNP58_07620	COG3265	gluconokinase activity
LNP58_07630	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LNP58_07705	COG1127	ABC transporter
LNP58_07710	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LNP58_07715	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LNP58_07730	COG2853	Lipoprotein
LNP58_07750	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LNP58_07815	COG0676	glucose-6-phosphate 1-epimerase activity
LNP58_07820	COG3039	Transposase
LNP58_07845	COG3039	Transposase
LNP58_07850	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LNP58_07860	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LNP58_07870	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LNP58_07875	COG1064	alcohol dehydrogenase
LNP58_07920	COG1522	sequence-specific DNA binding
LNP58_07925	COG3186	Phenylalanine-4-hydroxylase
LNP58_07965	COG2937	Belongs to the GPAT DAPAT family
LNP58_08000	COG0284	orotidine-5'-phosphate decarboxylase activity
LNP58_08005	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
LNP58_08010	COG3132	Protein of unknown function, DUF480
LNP58_08025	COG0210	DNA helicase
LNP58_08040	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
LNP58_08065	COG1028	Short-chain dehydrogenase reductase Sdr
LNP58_08090	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LNP58_08155	COG1166	arginine decarboxylase activity
LNP58_08160	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LNP58_08200	COG0606	chelatase, subunit chli
LNP58_08245	COG0366	Alpha amylase catalytic
LNP58_08250	COG0366	Alpha amylase catalytic
LNP58_08275	COG1609	Transcriptional regulator
LNP58_08325	COG0493	'glutamate synthase
LNP58_08330	COG0067	glutamate synthase
LNP58_08330	COG0069	glutamate synthase activity
LNP58_08330	COG0070	glutamate synthase
LNP58_08390	COG1111	helicase
LNP58_08390	COG1205	dead DEAH box helicase
LNP58_08395	COG1272	protein, Hemolysin III
LNP58_08435	COG1136	(ABC) transporter
LNP58_08495	COG2826	transposase and inactivated derivatives, IS30 family
LNP58_08520	COG3039	Transposase
LNP58_08530	COG1090	epimerase
LNP58_08550	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LNP58_08660	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LNP58_08735	COG3264	Mechanosensitive ion channel
LNP58_08735	COG1511	domain protein
LNP58_08760	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LNP58_08765	COG2354	Protein conserved in bacteria
LNP58_08770	COG1649	PFAM Uncharacterised BCR, COG1649
LNP58_08790	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LNP58_08815	COG0702	epimerase
LNP58_08830	COG1858	cytochrome C peroxidase
LNP58_08875	COG3039	Transposase
LNP58_08925	COG0513	Belongs to the DEAD box helicase family
LNP58_08930	COG3039	Transposase
LNP58_08970	COG1136	(ABC) transporter
LNP58_08980	COG3039	Transposase
LNP58_08990	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LNP58_09015	COG1755	Isoprenylcysteine carboxyl methyltransferase
LNP58_09020	COG1304	FMN binding
LNP58_09025	COG3039	Transposase
LNP58_09040	COG4772	TonB-dependent receptor
LNP58_09050	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
LNP58_09060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LNP58_09100	COG0501	Belongs to the peptidase M48B family
LNP58_09110	COG0187	DNA topoisomerase II activity
LNP58_09125	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LNP58_09145	COG0726	polysaccharide deacetylase
LNP58_09155	COG0671	phosphoesterase, PA-phosphatase related
LNP58_09165	COG0584	glycerophosphoryl diester phosphodiesterase
LNP58_09175	COG0861	Integral membrane protein TerC family
LNP58_09180	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LNP58_09195	COG2271	Major facilitator Superfamily
LNP58_09200	COG1929	Belongs to the glycerate kinase type-1 family
LNP58_09295	COG0477	Major facilitator Superfamily
LNP58_09325	COG0302	gtp cyclohydrolase
LNP58_09330	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LNP58_09375	COG2234	aminopeptidase activity
LNP58_09385	COG4942	peptidase
LNP58_09390	COG0793	Belongs to the peptidase S41A family
LNP58_09440	COG0386	Belongs to the glutathione peroxidase family
LNP58_09450	COG1322	Protein conserved in bacteria
LNP58_09460	COG0531	amino acid
LNP58_09475	COG0210	DNA helicase
LNP58_09490	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LNP58_09495	COG0583	DNA-binding transcription factor activity
LNP58_09500	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LNP58_09550	COG3540	Alkaline phosphatase
LNP58_09560	COG2091	lysine biosynthetic process via aminoadipic acid
LNP58_09575	COG0708	Exodeoxyribonuclease III
LNP58_09590	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LNP58_09595	COG3162	membrane
LNP58_09655	COG1028	Short-chain dehydrogenase reductase Sdr
LNP58_09660	COG0179	Fumarylacetoacetate (FAA) hydrolase
LNP58_09665	COG4948	Mandelate Racemase Muconate Lactonizing
LNP58_09670	COG4807	Protein conserved in bacteria
LNP58_09675	COG1643	Atp-dependent helicase
LNP58_09685	COG1187	pseudouridine synthase activity
LNP58_09695	COG0667	Aldo Keto reductase
LNP58_09700	COG2130	NADP-dependent
LNP58_09705	COG0656	L-ascorbic acid biosynthetic process
LNP58_09730	COG3039	Transposase
LNP58_09745	COG1752	Esterase of the alpha-beta hydrolase superfamily
LNP58_09755	COG1119	ATPase activity
LNP58_09770	COG0517	IMP dehydrogenase activity
LNP58_09770	COG1125	glycine betaine transport
LNP58_09785	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LNP58_09790	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
LNP58_09795	COG3550	peptidyl-serine autophosphorylation
LNP58_09800	COG1396	sequence-specific DNA binding
LNP58_09820	COG0489	protein tyrosine kinase activity
LNP58_09825	COG2062	phosphohistidine phosphatase, SixA
LNP58_09835	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LNP58_09875	COG1968	undecaprenyl-diphosphatase activity
LNP58_09880	COG0174	glutamine synthetase
LNP58_09885	COG0347	Belongs to the P(II) protein family
LNP58_09890	COG0004	ammonium transporteR
LNP58_09895	COG3852	Histidine kinase
LNP58_09900	COG2204	response regulator
LNP58_09905	COG2032	superoxide dismutase activity
LNP58_09910	COG2032	superoxide dismutase activity
LNP58_09950	COG1196	nuclear chromosome segregation
LNP58_09965	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LNP58_09970	COG1074	ATP-dependent DNA helicase activity
LNP58_09980	COG3549	Plasmid maintenance system killer
LNP58_10065	COG1764	response to oxidative stress
LNP58_10070	COG1846	Transcriptional regulator
LNP58_10160	COG2211	Major facilitator Superfamily
LNP58_10185	COG3693	PFAM glycoside hydrolase, family 10
LNP58_10210	COG0246	Mannitol dehydrogenase
LNP58_10215	COG1472	Belongs to the glycosyl hydrolase 3 family
LNP58_10225	COG4948	Mandelate Racemase Muconate Lactonizing
LNP58_10235	COG3661	Belongs to the glycosyl hydrolase 67 family
LNP58_10285	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LNP58_10295	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LNP58_10305	COG0805	protein transport
LNP58_10315	COG0519	Catalyzes the synthesis of GMP from XMP
LNP58_10315	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LNP58_10330	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LNP58_10345	COG0457	Tetratricopeptide repeat
LNP58_10350	COG4771	TonB-dependent receptor
LNP58_10365	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LNP58_10385	COG0523	cobalamin synthesis protein
LNP58_10440	COG1960	acyl-CoA dehydrogenase activity
LNP58_10445	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LNP58_10450	COG4770	biotin carboxylase activity
LNP58_10525	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LNP58_10575	COG0084	hydrolase, TatD family'
LNP58_10590	COG0583	DNA-binding transcription factor activity
LNP58_10595	COG2814	Major facilitator Superfamily
LNP58_10605	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LNP58_10610	COG1902	pentaerythritol trinitrate reductase activity
LNP58_10640	COG0745	RESPONSE REGULATOR receiver
LNP58_10660	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LNP58_10665	COG0583	DNA-binding transcription factor activity
LNP58_10695	COG0702	epimerase
LNP58_10700	COG1733	regulation of RNA biosynthetic process
LNP58_10755	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LNP58_10805	COG2911	Protein conserved in bacteria
LNP58_10810	COG0729	surface antigen
LNP58_10830	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LNP58_10835	COG3118	belongs to the thioredoxin family
LNP58_10845	COG2884	Cell division ATP-binding protein ftsE
LNP58_10850	COG2177	Part of the ABC transporter FtsEX involved in
LNP58_10855	COG2201	protein-glutamate methylesterase activity
LNP58_10860	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LNP58_10865	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LNP58_10875	COG1252	NADH dehydrogenase
LNP58_10905	COG0459	protein refolding
LNP58_10925	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LNP58_10950	COG3386	PFAM SMP-30 Gluconolaconase
LNP58_10965	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LNP58_10995	COG2353	YceI-like domain
LNP58_11085	COG0408	coproporphyrinogen oxidase activity
LNP58_11095	COG3039	Transposase
LNP58_11120	COG0129	dihydroxy-acid dehydratase activity
LNP58_11130	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LNP58_11180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LNP58_11185	COG0318	PFAM AMP-dependent synthetase and ligase
LNP58_11190	COG0727	PFAM Uncharacterised protein family (UPF0153)
LNP58_11195	COG0596	Alpha beta hydrolase
LNP58_11210	COG3177	Filamentation induced by cAMP protein fic
LNP58_11215	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LNP58_11230	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LNP58_11255	COG4191	Histidine kinase
LNP58_11260	COG0028	Belongs to the TPP enzyme family
LNP58_11275	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
LNP58_11280	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LNP58_11315	COG5383	Protein conserved in bacteria
LNP58_11325	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LNP58_11330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LNP58_11335	COG1473	amidohydrolase
LNP58_11345	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LNP58_11345	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LNP58_11355	COG3328	transposase activity
LNP58_11445	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LNP58_11460	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LNP58_11465	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
LNP58_11475	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
LNP58_11480	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LNP58_11485	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LNP58_11535	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LNP58_11550	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
LNP58_11615	COG0358	DNA primase activity
LNP58_11620	COG1295	ribonuclease BN
LNP58_11630	COG1610	YqeY-like protein
LNP58_11640	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LNP58_11645	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LNP58_11680	COG2133	pyrroloquinoline quinone binding
LNP58_11685	COG4682	membrane
LNP58_11720	COG0531	amino acid
LNP58_11755	COG4948	Mandelate Racemase Muconate Lactonizing
LNP58_11765	COG3023	N-Acetylmuramoyl-L-alanine amidase
LNP58_11770	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
LNP58_11800	COG3039	Transposase
LNP58_11850	COG0183	Belongs to the thiolase family
LNP58_11900	COG3483	tryptophan 2,3-dioxygenase activity
LNP58_11905	COG3104	oligopeptide transport
LNP58_11925	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
LNP58_11930	COG3039	Transposase
LNP58_11940	COG1320	monovalent cation:proton antiporter activity
LNP58_11945	COG2212	antiporter activity
LNP58_11955	COG0651	ATP synthesis coupled electron transport
LNP58_11960	COG1006	Multisubunit Na H antiporter MnhC subunit
LNP58_11965	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LNP58_11965	COG2111	Na H antiporter
LNP58_11995	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
LNP58_12005	COG0456	acetyltransferase
LNP58_12035	COG4221	oxidoreductase activity
LNP58_12095	COG0697	spore germination
LNP58_12100	COG4305	rare lipoprotein A
LNP58_12105	COG5297	Belongs to the glycosyl hydrolase family 6
LNP58_12115	COG1113	amino acid transport
LNP58_12125	COG0598	Magnesium transport protein CorA
LNP58_12195	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LNP58_12195	COG5297	Belongs to the glycosyl hydrolase family 6
LNP58_12200	COG0659	secondary active sulfate transmembrane transporter activity
LNP58_12235	COG3275	phosphorelay sensor kinase activity
LNP58_12245	COG0181	hydroxymethylbilane synthase activity
LNP58_12270	COG1505	serine-type exopeptidase activity
LNP58_12285	COG0436	Aminotransferase
LNP58_12315	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LNP58_12345	COG0308	aminopeptidase N
LNP58_12350	COG2199	diguanylate cyclase activity
LNP58_12395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LNP58_12400	COG1077	Cell shape determining protein MreB Mrl
LNP58_12405	COG1792	Involved in formation and maintenance of cell shape
LNP58_12420	COG0772	Belongs to the SEDS family
LNP58_12465	COG2951	lytic endotransglycosylase activity
LNP58_12470	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LNP58_12475	COG1686	Belongs to the peptidase S11 family
LNP58_12490	COG2921	Belongs to the UPF0250 family
LNP58_12540	COG1056	cytidyltransferase-related domain
LNP58_12540	COG1051	belongs to the nudix hydrolase family
LNP58_12575	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LNP58_12580	COG0673	inositol 2-dehydrogenase activity
LNP58_12585	COG2823	Periplasmic or secreted lipoprotein
LNP58_12590	COG4251	negative regulation of phosphorylation
LNP58_12595	COG0784	Response regulator, receiver
LNP58_12600	COG4191	Histidine kinase
LNP58_12605	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LNP58_12645	COG3250	beta-galactosidase activity
LNP58_12660	COG2188	Transcriptional regulator
LNP58_12670	COG1609	Transcriptional regulator
LNP58_12675	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LNP58_12680	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LNP58_12690	COG1215	transferase activity, transferring glycosyl groups
LNP58_12695	COG0726	polysaccharide deacetylase
LNP58_12695	COG1649	PFAM Uncharacterised BCR, COG1649
LNP58_12735	COG3039	Transposase
LNP58_12790	COG3039	Transposase
LNP58_12805	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LNP58_12810	COG3039	Transposase
LNP58_12845	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LNP58_12895	COG2205	protein histidine kinase activity
LNP58_12920	COG3791	Glutathione-dependent formaldehyde-activating
LNP58_12945	COG0488	(ABC) transporter
LNP58_12965	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LNP58_12985	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LNP58_12985	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LNP58_13005	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LNP58_13010	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LNP58_13015	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LNP58_13035	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
LNP58_13040	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LNP58_13050	COG2205	protein histidine kinase activity
LNP58_13055	COG0745	RESPONSE REGULATOR receiver
LNP58_13060	COG0277	FAD linked oxidase domain protein
LNP58_13065	COG1988	membrane-bound metal-dependent
LNP58_13070	COG0792	nuclease activity
LNP58_13105	COG0275	rRNA processing
LNP58_13110	COG3116	cell division
LNP58_13125	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LNP58_13145	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LNP58_13150	COG1181	Belongs to the D-alanine--D-alanine ligase family
LNP58_13155	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LNP58_13170	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
LNP58_13180	COG1388	LysM domain
LNP58_13180	COG4942	peptidase
LNP58_13195	COG0494	nUDIX hydrolase
LNP58_13210	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LNP58_13220	COG0604	alcohol dehydrogenase
LNP58_13220	COG1028	Short-chain dehydrogenase reductase Sdr
LNP58_13220	COG3321	synthase
LNP58_13275	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LNP58_13325	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LNP58_13340	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LNP58_13350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LNP58_13355	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LNP58_13365	COG0667	Aldo Keto reductase
LNP58_13415	COG2175	clavaminate synthase activity
LNP58_13425	COG4181	ATPase activity
LNP58_13440	COG0642	Histidine kinase
LNP58_13455	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LNP58_13475	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LNP58_13500	COG2967	ApaG domain
LNP58_13505	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LNP58_13515	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LNP58_13530	COG0123	including yeast histone deacetylase and acetoin utilization protein
LNP58_13535	COG2096	Adenosyltransferase
LNP58_13545	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LNP58_13550	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LNP58_13590	COG0583	DNA-binding transcription factor activity
LNP58_13595	COG0318	PFAM AMP-dependent synthetase and ligase
LNP58_13605	COG1024	Enoyl-CoA hydratase
LNP58_13625	COG3386	PFAM SMP-30 Gluconolaconase
LNP58_13755	COG0446	pyridine nucleotide-disulphide oxidoreductase
LNP58_13755	COG1902	pentaerythritol trinitrate reductase activity
LNP58_13760	COG0604	alcohol dehydrogenase
LNP58_13785	COG0156	8-amino-7-oxononanoate synthase activity
LNP58_13790	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LNP58_13795	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LNP58_13800	COG4208	sulfate ABC transporter
LNP58_13805	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
LNP58_13835	COG0406	alpha-ribazole phosphatase activity
LNP58_13845	COG0285	dihydrofolate synthase activity
LNP58_13865	COG2833	Protein of unknown function (DUF455)
LNP58_13885	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LNP58_13890	COG0671	phosphoesterase, PA-phosphatase related
LNP58_13895	COG0438	transferase activity, transferring glycosyl groups
LNP58_13905	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LNP58_13920	COG4783	chaperone-mediated protein folding
LNP58_13980	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LNP58_13985	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LNP58_13990	COG0583	DNA-binding transcription factor activity
LNP58_13995	COG3634	alkyl hydroperoxide reductase activity
LNP58_14005	COG2890	protein-(glutamine-N5) methyltransferase activity
LNP58_14055	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LNP58_14055	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LNP58_14070	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
LNP58_14095	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
LNP58_14120	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LNP58_14130	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LNP58_14160	COG1295	ribonuclease BN
LNP58_14165	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LNP58_14185	COG0521	Mo-molybdopterin cofactor biosynthetic process
LNP58_14195	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LNP58_14210	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
LNP58_14225	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LNP58_14235	COG0193	aminoacyl-tRNA hydrolase activity
LNP58_14240	COG0012	GTP binding
LNP58_14270	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LNP58_14275	COG0250	Participates in transcription elongation, termination and antitermination
LNP58_14280	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LNP58_14290	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LNP58_14295	COG0222	ribosome binding
LNP58_14300	COG0085	RNA polymerase activity
LNP58_14305	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LNP58_14310	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LNP58_14315	COG0049	tRNA binding
LNP58_14335	COG0051	transcription antitermination factor activity, RNA binding
LNP58_14340	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LNP58_14345	COG0088	Forms part of the polypeptide exit tunnel
LNP58_14350	COG0089	rRNA binding
LNP58_14365	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LNP58_14375	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LNP58_14380	COG0255	Belongs to the universal ribosomal protein uL29 family
LNP58_14385	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LNP58_14390	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LNP58_14400	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LNP58_14430	COG1841	ribosomal large subunit assembly
LNP58_14440	COG0201	protein transport
LNP58_14450	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LNP58_14455	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LNP58_14465	COG0203	ribosomal protein L17
LNP58_14525	COG3551	Protein conserved in bacteria
LNP58_14555	COG2194	sulfuric ester hydrolase activity
LNP58_14565	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LNP58_14570	COG0745	RESPONSE REGULATOR receiver
LNP58_14575	COG0642	Histidine kinase
LNP58_14585	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
LNP58_14590	COG2894	cell division
LNP58_14605	COG4585	Histidine kinase
LNP58_14610	COG2197	response regulator
LNP58_14625	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LNP58_14655	COG2963	transposase activity
LNP58_14715	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LNP58_14725	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LNP58_14790	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LNP58_14865	COG3039	Transposase
LNP58_14920	COG3179	chitinase
LNP58_15095	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
LNP58_15115	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LNP58_15120	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
LNP58_15125	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
LNP58_15140	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LNP58_15180	COG3039	Transposase
LNP58_15240	COG1297	OPT oligopeptide transporter protein
LNP58_15245	COG3039	Transposase
LNP58_15265	COG1506	peptidase
LNP58_15265	COG0823	Involved in the tonB-independent uptake of proteins
LNP58_15295	COG2207	Transcriptional regulator
LNP58_15295	COG1917	Cupin 2, conserved barrel domain protein
LNP58_15345	COG0753	catalase activity
LNP58_15385	COG0469	pyruvate kinase activity
LNP58_15390	COG3588	fructose-bisphosphate aldolase
LNP58_15395	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
LNP58_15440	COG2205	protein histidine kinase activity
LNP58_15440	COG2198	Histidine kinase
LNP58_15440	COG0784	Response regulator, receiver
LNP58_15460	COG0175	sulfate reduction
LNP58_15465	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LNP58_15470	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LNP58_15475	COG0175	sulfate reduction
LNP58_15480	COG0529	Catalyzes the synthesis of activated sulfate
LNP58_15480	COG2895	sulfate adenylyltransferase (ATP) activity
LNP58_15490	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LNP58_15495	COG0308	aminopeptidase N
LNP58_15515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LNP58_15520	COG2272	Belongs to the type-B carboxylesterase lipase family
LNP58_15540	COG1970	mechanosensitive ion channel activity
LNP58_15570	COG0471	metal ion transport
LNP58_15570	COG3273	potassium ion transport
LNP58_15580	COG2022	thiamine diphosphate biosynthetic process
LNP58_15725	COG3118	belongs to the thioredoxin family
LNP58_15750	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LNP58_15775	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LNP58_15800	COG2968	Membrane
LNP58_15815	COG3164	Protein of unknown function
LNP58_15825	COG0312	modulator of DNA gyrase
LNP58_15830	COG3028	Belongs to the UPF0307 family
LNP58_15835	COG0312	modulator of DNA gyrase
LNP58_15860	COG0142	geranyltranstransferase activity
LNP58_15865	COG1722	exodeoxyribonuclease VII activity
LNP58_15870	COG0037	tRNA processing
LNP58_15875	COG1785	Belongs to the alkaline phosphatase family
LNP58_15900	COG0791	NLP P60 protein
LNP58_15905	COG0791	NLP P60 protein
LNP58_15910	COG1047	Peptidyl-prolyl cis-trans
LNP58_15915	COG2311	Membrane
LNP58_15920	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LNP58_15960	COG0489	protein tyrosine kinase activity
LNP58_15965	COG0717	Belongs to the dCTP deaminase family
LNP58_15995	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LNP58_16040	COG2890	protein-(glutamine-N5) methyltransferase activity
LNP58_16045	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LNP58_16050	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LNP58_16055	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LNP58_16075	COG0101	tRNA pseudouridine synthase activity
LNP58_16080	COG0135	phosphoribosylanthranilate isomerase activity
LNP58_16090	COG0133	tryptophan synthase activity
LNP58_16105	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LNP58_16110	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LNP58_16160	COG0149	triose-phosphate isomerase activity
LNP58_16175	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LNP58_16185	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LNP58_16190	COG0649	NAD binding
LNP58_16195	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
LNP58_16200	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LNP58_16205	COG1034	ATP synthesis coupled electron transport
LNP58_16210	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LNP58_16240	COG1007	ATP synthesis coupled electron transport
LNP58_16250	COG0779	Required for maturation of 30S ribosomal subunits
LNP58_16255	COG0195	Participates in both transcription termination and antitermination
LNP58_16275	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LNP58_16280	COG1185	polyribonucleotide nucleotidyltransferase activity
LNP58_16315	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LNP58_16325	COG2095	MarC family integral membrane protein
LNP58_16340	COG1611	Belongs to the LOG family
LNP58_16380	COG4969	Belongs to the N-Me-Phe pilin family
LNP58_16385	COG0556	nucleotide-excision repair
LNP58_16420	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LNP58_16490	COG0438	transferase activity, transferring glycosyl groups
LNP58_16495	COG0438	transferase activity, transferring glycosyl groups
LNP58_16505	COG0438	transferase activity, transferring glycosyl groups
LNP58_16545	COG3040	lipid binding
LNP58_16630	COG0784	Response regulator, receiver
LNP58_16630	COG4191	Histidine kinase
LNP58_16650	COG0552	protein localization to endoplasmic reticulum
LNP58_16660	COG3938	Belongs to the proline racemase family
LNP58_16665	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LNP58_16680	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LNP58_16690	COG0006	proline dipeptidase activity
LNP58_16705	COG0531	amino acid
LNP58_16735	COG4206	TonB-dependent receptor
LNP58_16825	COG0746	molybdenum cofactor guanylyltransferase activity
LNP58_16850	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LNP58_16850	COG1648	precorrin-2 dehydrogenase activity
LNP58_16885	COG3039	Transposase
LNP58_16890	COG3039	Transposase
LNP58_16925	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LNP58_16945	COG3039	Transposase
LNP58_16950	COG1054	Belongs to the UPF0176 family
LNP58_16965	COG1530	ribonuclease E activity
LNP58_16975	COG3064	Membrane
LNP58_16990	COG2154	pterin-4-alpha-carbinolamine dehydratase
LNP58_16995	COG0316	Belongs to the HesB IscA family
LNP58_16995	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
LNP58_17045	COG3039	Transposase
LNP58_17060	COG3039	Transposase
LNP58_17165	COG0631	protein serine/threonine phosphatase activity
LNP58_17170	COG0515	serine threonine protein kinase
LNP58_17205	COG1858	cytochrome C peroxidase
LNP58_17260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LNP58_17330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LNP58_17350	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LNP58_17365	COG1595	DNA-templated transcription, initiation
LNP58_17415	COG2244	polysaccharide biosynthetic process
LNP58_17445	COG2264	protein methyltransferase activity
LNP58_17455	COG0438	transferase activity, transferring glycosyl groups
LNP58_17475	COG1136	(ABC) transporter
LNP58_17480	COG1132	(ABC) transporter
LNP58_17490	COG0477	Major facilitator Superfamily
LNP58_17500	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LNP58_17515	COG1253	flavin adenine dinucleotide binding
LNP58_17525	COG0306	phosphate transporter
LNP58_17530	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LNP58_17555	COG0504	CTP synthase activity
LNP58_17560	COG2877	3-deoxy-8-phosphooctulonate synthase activity
LNP58_17570	COG0148	phosphopyruvate hydratase activity
LNP58_17575	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LNP58_17590	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LNP58_17600	COG2840	Smr protein MutS2
LNP58_17605	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LNP58_17610	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LNP58_17615	COG1238	metal cluster binding
LNP58_17630	COG1534	Rna-binding protein
LNP58_17635	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
LNP58_17645	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LNP58_17660	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LNP58_17665	COG1546	Belongs to the CinA family
LNP58_17680	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LNP58_17685	COG2137	regulation of response to DNA damage stimulus
LNP58_17690	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LNP58_17695	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LNP58_17715	COG0305	Participates in initiation and elongation during chromosome replication
LNP58_17720	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LNP58_17735	COG1741	Belongs to the pirin family
LNP58_17740	COG0583	DNA-binding transcription factor activity
LNP58_17765	COG0351	phosphomethylpyrimidine kinase
LNP58_17775	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LNP58_17780	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LNP58_17795	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LNP58_17805	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LNP58_17810	COG3734	2-keto-3-deoxy-galactonokinase
LNP58_17820	COG4948	Mandelate Racemase Muconate Lactonizing
LNP58_17825	COG0800	Aldolase
LNP58_17840	COG1501	Belongs to the glycosyl hydrolase 31 family
LNP58_17850	COG1070	Carbohydrate kinase
LNP58_17860	COG0477	Major facilitator Superfamily
LNP58_17880	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LNP58_17925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LNP58_17930	COG2258	MOSC domain
LNP58_17940	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LNP58_17945	COG0505	Belongs to the CarA family
LNP58_17955	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LNP58_17960	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LNP58_17970	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LNP58_18030	COG0784	Response regulator, receiver
LNP58_18030	COG2198	Histidine kinase
LNP58_18030	COG2205	protein histidine kinase activity
LNP58_18035	COG1024	Enoyl-CoA hydratase
LNP58_18040	COG0318	PFAM AMP-dependent synthetase and ligase
LNP58_18070	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LNP58_18100	COG0840	transmembrane signaling receptor activity
LNP58_18120	COG0835	chemotaxis
LNP58_18135	COG0840	transmembrane signaling receptor activity
LNP58_18140	COG0840	transmembrane signaling receptor activity
LNP58_18145	COG0840	transmembrane signaling receptor activity
LNP58_18150	COG0840	transmembrane signaling receptor activity
LNP58_18160	COG0840	transmembrane signaling receptor activity
LNP58_18170	COG0840	transmembrane signaling receptor activity
LNP58_18200	COG0745	RESPONSE REGULATOR receiver
LNP58_18210	COG0835	chemotaxis
LNP58_18220	COG1360	Flagellar Motor Protein
LNP58_18225	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LNP58_18245	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LNP58_18255	COG4771	TonB-dependent receptor
LNP58_18280	COG3039	Transposase
LNP58_18390	COG3039	Transposase
LNP58_18405	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LNP58_18405	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LNP58_18410	COG1105	Belongs to the carbohydrate kinase PfkB family
LNP58_18415	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LNP58_18415	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LNP58_18420	COG1609	Transcriptional regulator
LNP58_18440	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LNP58_18445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LNP58_18455	COG2902	Dehydrogenase
LNP58_18460	COG3039	Transposase
LNP58_18470	COG0784	Response regulator, receiver
LNP58_18470	COG2205	protein histidine kinase activity
LNP58_18470	COG5002	protein histidine kinase activity
LNP58_18475	COG2733	membrane
LNP58_18485	COG1121	(ABC) transporter
LNP58_18490	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LNP58_18495	COG2223	nitrite transmembrane transporter activity
LNP58_18505	COG0243	molybdopterin cofactor binding
LNP58_18515	COG0477	Major facilitator Superfamily
LNP58_18525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LNP58_18530	COG0174	glutamine synthetase
LNP58_18565	COG3842	ATPase activity
LNP58_18585	COG1012	belongs to the aldehyde dehydrogenase family
LNP58_18600	COG4535	Mg2 and Co2 transporter CorC
LNP58_18620	COG1702	phosphate starvation-inducible protein PhoH
LNP58_18650	COG0741	lytic transglycosylase activity
LNP58_18655	COG0723	plastoquinol--plastocyanin reductase activity
LNP58_18660	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LNP58_18665	COG2857	Cytochrome c1
LNP58_18670	COG0625	glutathione transferase activity
LNP58_18675	COG2969	positive regulation of protein catabolic process
LNP58_18700	COG2094	Belongs to the DNA glycosylase MPG family
LNP58_18710	COG3328	transposase activity
LNP58_18775	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LNP58_18800	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LNP58_18805	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LNP58_18805	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LNP58_18810	COG0802	atpase or kinase
LNP58_18815	COG0860	N-Acetylmuramoyl-L-alanine amidase
LNP58_18820	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LNP58_18840	COG1028	Short-chain dehydrogenase reductase Sdr
LNP58_18860	COG2081	HI0933 family
LNP58_18865	COG4681	YaeQ
LNP58_18870	COG1671	Belongs to the UPF0178 family
LNP58_18880	COG0625	glutathione transferase activity
LNP58_18900	COG0513	Belongs to the DEAD box helicase family
LNP58_18905	COG0488	(ABC) transporter
LNP58_18925	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LNP58_18930	COG0483	inositol monophosphate 1-phosphatase activity
LNP58_18945	COG3300	MHYT domain
LNP58_18945	COG5001	Diguanylate cyclase
LNP58_18950	COG1509	lysine 2,3-aminomutase activity
LNP58_18965	COG0402	S-adenosylhomocysteine deaminase activity
LNP58_18970	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LNP58_18995	COG4677	pectinesterase activity
LNP58_19005	COG3039	Transposase
LNP58_19040	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LNP58_19065	COG2166	iron-sulfur cluster assembly
LNP58_19080	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LNP58_19085	COG0137	argininosuccinate synthase activity
LNP58_19095	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LNP58_19100	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LNP58_19115	COG0165	Argininosuccinate lyase
LNP58_19135	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LNP58_19170	COG4988	ABC transporter
LNP58_19175	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LNP58_19250	COG3039	Transposase
LNP58_19260	COG3039	Transposase
LNP58_19270	COG3209	COG3209 Rhs family protein
LNP58_19280	COG3039	Transposase
LNP58_19310	COG0643	Histidine kinase
LNP58_19310	COG2198	Histidine kinase
LNP58_19310	COG0784	Response regulator, receiver
LNP58_19365	COG1684	flagellar biosynthetic protein fliR
LNP58_19380	COG3190	flagellar
LNP58_19430	COG1677	Flagellar hook-basal body complex protein FliE
LNP58_19460	COG1028	Short-chain dehydrogenase reductase Sdr
LNP58_19470	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LNP58_19490	COG2201	protein-glutamate methylesterase activity
LNP58_19525	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LNP58_19530	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LNP58_19565	COG4787	bacterial-type flagellum-dependent cell motility
LNP58_19575	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
LNP58_19580	COG1558	bacterial-type flagellum-dependent cell motility
LNP58_19590	COG0835	chemotaxis
LNP58_19590	COG0784	Response regulator, receiver
LNP58_19610	COG5002	protein histidine kinase activity
LNP58_19620	COG4585	Histidine kinase
LNP58_19625	COG5001	Diguanylate cyclase
LNP58_19650	COG0482	sulfurtransferase activity
LNP58_19665	COG0542	response to heat
LNP58_19700	COG0492	ferredoxin-NADP+ reductase activity
LNP58_19705	COG1674	ftsk spoiiie
LNP58_19725	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LNP58_19745	COG0038	chloride channel
LNP58_19750	COG0183	Belongs to the thiolase family
LNP58_19755	COG1024	Enoyl-CoA hydratase
LNP58_19755	COG1250	3-hydroxyacyl-CoA dehydrogenase
LNP58_19770	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LNP58_19780	COG1426	Protein conserved in bacteria
LNP58_19790	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LNP58_19800	COG0303	'Molybdopterin
LNP58_19830	COG3039	Transposase
LNP58_19865	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LNP58_19885	COG0742	ribosomal rna small subunit methyltransferase
LNP58_19890	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LNP58_19900	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LNP58_19905	COG0405	Gamma-glutamyltransferase
LNP58_19980	COG0343	queuine tRNA-ribosyltransferase activity
LNP58_19985	COG1862	Preprotein translocase
LNP58_19990	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LNP58_19995	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LNP58_20005	COG3039	Transposase
LNP58_20040	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LNP58_20050	COG0704	Plays a role in the regulation of phosphate uptake
LNP58_20065	COG0573	inorganic phosphate transmembrane transporter activity
LNP58_20070	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LNP58_20110	COG3039	Transposase
LNP58_20130	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LNP58_20140	COG1024	Enoyl-CoA hydratase
LNP58_20155	COG0494	nUDIX hydrolase
LNP58_20200	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LNP58_20200	COG0116	Belongs to the methyltransferase superfamily
LNP58_20225	COG0667	Aldo Keto reductase
LNP58_20235	COG2925	Exonuclease
LNP58_20260	COG0288	reversible hydration of carbon dioxide
LNP58_20290	COG0316	Belongs to the HesB IscA family
LNP58_20295	COG0360	Binds together with S18 to 16S ribosomal RNA
LNP58_20305	COG0359	binds to the 23S rRNA
LNP58_20315	COG3115	cell septum assembly
LNP58_20335	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
LNP58_20350	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
LNP58_20375	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LNP58_20385	COG2986	histidine ammonia-lyase
LNP58_20390	COG1228	amidohydrolase
LNP58_20430	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LNP58_20440	COG0077	Prephenate dehydratase
LNP58_20440	COG1605	Chorismate mutase
LNP58_20445	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LNP58_20475	COG4566	intracellular signal transduction
LNP58_20520	COG0860	N-Acetylmuramoyl-L-alanine amidase
LNP58_20525	COG1469	GTP cyclohydrolase I activity
LNP58_20535	COG0617	tRNA 3'-terminal CCA addition
LNP58_20550	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LNP58_20580	COG1472	Belongs to the glycosyl hydrolase 3 family
LNP58_20595	COG2203	Gaf domain
LNP58_20595	COG3706	GGDEF domain
LNP58_20595	COG4251	negative regulation of phosphorylation
LNP58_20595	COG5001	Diguanylate cyclase
LNP58_20680	COG0386	Belongs to the glutathione peroxidase family
LNP58_20755	COG5002	protein histidine kinase activity
LNP58_20755	COG2205	protein histidine kinase activity
LNP58_20755	COG0784	Response regulator, receiver
LNP58_20785	COG0800	Aldolase
LNP58_20790	COG0129	dihydroxy-acid dehydratase activity
LNP58_20795	COG0363	glucosamine-6-phosphate deaminase activity
LNP58_20805	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LNP58_20820	COG0354	folic acid binding
LNP58_20835	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LNP58_20850	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LNP58_20865	COG4591	ABC-type transport system involved in lipoprotein release permease component
LNP58_20890	COG0811	peptide transport
LNP58_20905	COG1663	tetraacyldisaccharide 4'-kinase activity
LNP58_20915	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LNP58_20925	COG0322	excinuclease ABC activity
LNP58_20960	COG3328	transposase activity
LNP58_20975	COG2201	protein-glutamate methylesterase activity
LNP58_21205	COG0140	phosphoribosyl-ATP diphosphatase activity
LNP58_21205	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LNP58_21215	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LNP58_21225	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LNP58_21225	COG0131	Imidazoleglycerol-phosphate dehydratase
LNP58_21240	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LNP58_21260	COG0124	histidyl-tRNA synthetase
LNP58_21275	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LNP58_21310	COG1012	belongs to the aldehyde dehydrogenase family
LNP58_21340	COG0697	spore germination
LNP58_21365	COG0671	phosphoesterase, PA-phosphatase related
LNP58_21380	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
LNP58_21395	COG2183	response to ionizing radiation
LNP58_21405	COG0723	plastoquinol--plastocyanin reductase activity
LNP58_21405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LNP58_21420	COG3243	poly(R)-hydroxyalkanoic acid synthase
LNP58_21430	COG1183	phosphatidylcholine synthase activity
LNP58_21435	COG1028	Short-chain dehydrogenase reductase Sdr
LNP58_21485	COG0668	transmembrane transport
LNP58_21505	COG1914	H( )-stimulated, divalent metal cation uptake system
LNP58_21540	COG1028	Short-chain dehydrogenase reductase Sdr
LNP58_21555	COG0583	DNA-binding transcription factor activity
LNP58_21560	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LNP58_21565	COG3002	Belongs to the UPF0753 family
LNP58_21580	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LNP58_21600	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LNP58_21610	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LNP58_21615	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
LNP58_21625	COG0776	regulation of translation
LNP58_21630	COG0539	negative regulation of cytoplasmic translation
LNP58_21635	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LNP58_21650	COG2957	Belongs to the agmatine deiminase family
LNP58_21660	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LNP58_21685	COG0395	ABC-type sugar transport system, permease component
LNP58_21690	COG1175	transmembrane transport
LNP58_21720	COG2350	Protein conserved in bacteria
LNP58_21725	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LNP58_21730	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LNP58_21735	COG1187	pseudouridine synthase activity
LNP58_21760	COG0436	Aminotransferase
LNP58_21825	COG0277	FAD linked oxidase domain protein
LNP58_21830	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LNP58_21840	COG0531	amino acid
LNP58_21845	COG0531	amino acid
LNP58_21855	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
LNP58_21885	COG2201	protein-glutamate methylesterase activity
LNP58_21935	COG0583	DNA-binding transcription factor activity
LNP58_21945	COG3039	Transposase
LNP58_21995	COG3039	Transposase
LNP58_22045	COG3039	Transposase
LNP58_22055	COG3039	Transposase
LNP58_22080	COG3328	transposase activity
LNP58_22100	COG3039	Transposase
LNP58_22110	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LNP58_22130	COG0557	exoribonuclease II activity
LNP58_22155	COG1960	acyl-CoA dehydrogenase activity
LNP58_22160	COG2226	methyltransferase
LNP58_22165	COG0646	methionine synthase
LNP58_22165	COG1410	methionine synthase
LNP58_22170	COG1410	methionine synthase
LNP58_22170	COG0646	methionine synthase
LNP58_22180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LNP58_22190	COG1609	Transcriptional regulator
LNP58_22205	COG2900	Belongs to the SlyX family
LNP58_22220	COG0386	Belongs to the glutathione peroxidase family
LNP58_22230	COG1725	Transcriptional regulator
LNP58_22235	COG1131	(ABC) transporter
LNP58_22310	COG2850	peptidyl-arginine hydroxylation
LNP58_22345	COG1132	(ABC) transporter
LNP58_22370	COG1605	Chorismate mutase
LNP58_22370	COG0287	Prephenate dehydrogenase
LNP58_22375	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
LNP58_22380	COG0484	heat shock protein binding
LNP58_22385	COG0443	Heat shock 70 kDa protein
LNP58_22390	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LNP58_22400	COG0497	DNA recombination
LNP58_22410	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LNP58_22415	COG2914	Belongs to the UPF0125 (RnfH) family
LNP58_22440	COG1960	acyl-CoA dehydrogenase activity
LNP58_22450	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LNP58_22495	COG2814	Major facilitator Superfamily
LNP58_22500	COG1566	PFAM secretion protein HlyD family protein
LNP58_22535	COG4774	siderophore transport
LNP58_22545	COG0367	asparagine synthase
LNP58_22560	COG1393	Belongs to the ArsC family
LNP58_22620	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LNP58_22635	COG0233	cytoplasmic translational termination
LNP58_22645	COG0575	Belongs to the CDS family
LNP58_22655	COG0750	zinc metalloprotease
LNP58_22675	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LNP58_22680	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LNP58_22700	COG0825	malonyl-CoA metabolic process
LNP58_22710	COG4771	TonB-dependent receptor
LNP58_22715	COG1131	(ABC) transporter
LNP58_22740	COG1981	membrane
LNP58_22785	COG0529	Catalyzes the synthesis of activated sulfate
LNP58_22785	COG2895	sulfate adenylyltransferase (ATP) activity
LNP58_22820	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LNP58_22835	COG2040	homocysteine
LNP58_22840	COG0833	amino acid
LNP58_22860	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LNP58_22860	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LNP58_22870	COG2878	Part of a membrane complex involved in electron transport
LNP58_22885	COG1595	DNA-templated transcription, initiation
LNP58_22910	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LNP58_22925	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LNP58_22930	COG0251	oxidation-reduction process
LNP58_22940	COG0392	lysyltransferase activity
LNP58_22940	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LNP58_22985	COG2814	Major facilitator Superfamily
LNP58_22990	COG1902	pentaerythritol trinitrate reductase activity
LNP58_23000	COG2824	Alkylphosphonate utilization operon protein PhnA
LNP58_23015	COG1047	Peptidyl-prolyl cis-trans
LNP58_23050	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LNP58_23090	COG0183	Belongs to the thiolase family
LNP58_23120	COG1793	dna ligase
LNP58_23120	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
LNP58_23130	COG1793	dna ligase
LNP58_23135	COG1201	RNA secondary structure unwinding
LNP58_23165	COG1278	Cold shock
LNP58_23170	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LNP58_23175	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LNP58_23185	COG3046	protein related to deoxyribodipyrimidine photolyase
LNP58_23190	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
LNP58_23195	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LNP58_23210	COG2954	triphosphatase activity
LNP58_23225	COG1381	Involved in DNA repair and RecF pathway recombination
LNP58_23255	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LNP58_23270	COG1024	Enoyl-CoA hydratase
LNP58_23270	COG1250	3-hydroxyacyl-CoA dehydrogenase
LNP58_23290	COG1024	Enoyl-CoA hydratase
LNP58_23295	COG1960	acyl-CoA dehydrogenase activity
LNP58_23315	COG3867	Arabinogalactan endo-beta-1,4-galactanase