locus-tag	class	description
LUZ17_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LUZ17_00020	COG0187	DNA topoisomerase II activity
LUZ17_00030	COG0501	Belongs to the peptidase M48B family
LUZ17_00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LUZ17_00080	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
LUZ17_00090	COG4772	TonB-dependent receptor
LUZ17_00105	COG3039	Transposase
LUZ17_00110	COG1304	FMN binding
LUZ17_00140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LUZ17_00150	COG3039	Transposase
LUZ17_00160	COG1136	(ABC) transporter
LUZ17_00205	COG3039	Transposase
LUZ17_00210	COG0513	Belongs to the DEAD box helicase family
LUZ17_00260	COG3039	Transposase
LUZ17_00305	COG1858	cytochrome C peroxidase
LUZ17_00320	COG0702	epimerase
LUZ17_00345	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LUZ17_00365	COG1649	PFAM Uncharacterised BCR, COG1649
LUZ17_00370	COG2354	Protein conserved in bacteria
LUZ17_00375	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LUZ17_00390	COG3264	Mechanosensitive ion channel
LUZ17_00390	COG1511	domain protein
LUZ17_00465	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LUZ17_00575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LUZ17_00595	COG1090	epimerase
LUZ17_00605	COG3039	Transposase
LUZ17_00630	COG2826	transposase and inactivated derivatives, IS30 family
LUZ17_00690	COG1136	(ABC) transporter
LUZ17_00730	COG1272	protein, Hemolysin III
LUZ17_00735	COG1111	helicase
LUZ17_00735	COG1205	dead DEAH box helicase
LUZ17_00795	COG0067	glutamate synthase
LUZ17_00795	COG0069	glutamate synthase activity
LUZ17_00795	COG0070	glutamate synthase
LUZ17_00800	COG0493	'glutamate synthase
LUZ17_00850	COG1609	Transcriptional regulator
LUZ17_00875	COG0366	Alpha amylase catalytic
LUZ17_00880	COG0366	Alpha amylase catalytic
LUZ17_00925	COG0606	chelatase, subunit chli
LUZ17_00965	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LUZ17_00970	COG1166	arginine decarboxylase activity
LUZ17_01035	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LUZ17_01060	COG1028	Short-chain dehydrogenase reductase Sdr
LUZ17_01085	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
LUZ17_01100	COG0210	DNA helicase
LUZ17_01115	COG3132	Protein of unknown function, DUF480
LUZ17_01120	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
LUZ17_01125	COG0284	orotidine-5'-phosphate decarboxylase activity
LUZ17_01160	COG2937	Belongs to the GPAT DAPAT family
LUZ17_01165	COG0604	alcohol dehydrogenase
LUZ17_01165	COG1028	Short-chain dehydrogenase reductase Sdr
LUZ17_01165	COG3321	synthase
LUZ17_01200	COG3186	Phenylalanine-4-hydroxylase
LUZ17_01205	COG1522	sequence-specific DNA binding
LUZ17_01250	COG1064	alcohol dehydrogenase
LUZ17_01255	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LUZ17_01265	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LUZ17_01275	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LUZ17_01300	COG3039	Transposase
LUZ17_01305	COG0676	glucose-6-phosphate 1-epimerase activity
LUZ17_01370	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LUZ17_01390	COG2853	Lipoprotein
LUZ17_01405	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LUZ17_01410	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LUZ17_01415	COG1127	ABC transporter
LUZ17_01490	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LUZ17_01500	COG3265	gluconokinase activity
LUZ17_01505	COG2211	Major facilitator Superfamily
LUZ17_01510	COG3459	Glycosyltransferase 36 associated
LUZ17_01520	COG2205	protein histidine kinase activity
LUZ17_01530	COG1414	Transcriptional regulator
LUZ17_01535	COG0738	Major facilitator superfamily
LUZ17_01540	COG3254	rhamnose metabolic process
LUZ17_01570	COG0339	signal peptide processing
LUZ17_01600	COG0564	pseudouridine synthase activity
LUZ17_01610	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LUZ17_01620	COG1181	Belongs to the D-alanine--D-alanine ligase family
LUZ17_01630	COG3039	Transposase
LUZ17_01710	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LUZ17_01720	COG0842	Transport permease protein
LUZ17_01725	COG1131	(ABC) transporter
LUZ17_01730	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LUZ17_01755	COG1476	TRANSCRIPTIONal
LUZ17_01765	COG4555	ABC transporter
LUZ17_01800	COG0625	glutathione transferase activity
LUZ17_01845	COG0583	DNA-binding transcription factor activity
LUZ17_01885	COG1199	ATP-dependent helicase activity
LUZ17_01925	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LUZ17_01955	COG3228	Belongs to the MtfA family
LUZ17_01965	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
LUZ17_01965	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
LUZ17_01970	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LUZ17_01985	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LUZ17_02020	COG3237	CsbD-like
LUZ17_02025	COG0180	Tryptophanyl-tRNA synthetase
LUZ17_02030	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LUZ17_02075	COG0753	catalase activity
LUZ17_02080	COG1595	DNA-templated transcription, initiation
LUZ17_02090	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LUZ17_02100	COG0628	permease
LUZ17_02110	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LUZ17_02115	COG1040	competence protein
LUZ17_02120	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LUZ17_02125	COG0156	8-amino-7-oxononanoate synthase activity
LUZ17_02135	COG1028	Short-chain dehydrogenase reductase Sdr
LUZ17_02150	COG0463	Glycosyl transferase, family 2
LUZ17_02160	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LUZ17_02165	COG3100	YcgL domain-containing protein
LUZ17_02180	COG3387	PFAM Glycoside hydrolase 15-related
LUZ17_02185	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LUZ17_02200	COG2239	Acts as a magnesium transporter
LUZ17_02210	COG1042	CoA-binding domain protein
LUZ17_02210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LUZ17_02210	COG0045	succinate-CoA ligase (ADP-forming) activity
LUZ17_02220	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LUZ17_02225	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LUZ17_02260	COG3485	protocatechuate 3,4-dioxygenase
LUZ17_02265	COG3485	protocatechuate 3,4-dioxygenase
LUZ17_02280	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LUZ17_02285	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LUZ17_02310	COG4221	oxidoreductase activity
LUZ17_02325	COG0018	arginyl-trna synthetase
LUZ17_02330	COG2003	Belongs to the UPF0758 family
LUZ17_02335	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LUZ17_02360	COG0463	Glycosyl transferase, family 2
LUZ17_02375	COG1475	DNA binding
LUZ17_02380	COG1192	Involved in chromosome partitioning
LUZ17_02395	COG0708	Exodeoxyribonuclease III
LUZ17_02400	COG2211	Major facilitator Superfamily
LUZ17_02415	COG0739	heme binding
LUZ17_02460	COG0745	RESPONSE REGULATOR receiver
LUZ17_02500	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
LUZ17_02515	COG2814	Major facilitator Superfamily
LUZ17_02530	COG1289	transmembrane transporter activity
LUZ17_02540	COG0577	efflux transmembrane transporter activity
LUZ17_02540	COG1136	(ABC) transporter
LUZ17_02545	COG0151	Belongs to the GarS family
LUZ17_02555	COG0419	ATPase involved in DNA repair
LUZ17_02590	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
LUZ17_02630	COG0439	Biotin carboxylase
LUZ17_02640	COG0511	ligase activity, forming carbon-carbon bonds
LUZ17_02645	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LUZ17_02655	COG1324	tolerance protein
LUZ17_02690	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LUZ17_02710	COG0534	Mate efflux family protein
LUZ17_02715	COG0616	signal peptide processing
LUZ17_02725	COG1028	Short-chain dehydrogenase reductase Sdr
LUZ17_02740	COG0009	L-threonylcarbamoyladenylate synthase
LUZ17_02745	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LUZ17_02745	COG1754	DNA topoisomerase type I activity
LUZ17_02760	COG2922	Belongs to the Smg family
LUZ17_02765	COG0758	DNA mediated transformation
LUZ17_02770	COG1652	LysM domain
LUZ17_02775	COG0242	peptide deformylase activity
LUZ17_02780	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LUZ17_02785	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LUZ17_02785	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LUZ17_02835	COG1560	Kdo2-lipid A biosynthetic process
LUZ17_02845	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LUZ17_03070	COG1294	oxidase, subunit
LUZ17_03075	COG1271	oxidase subunit
LUZ17_03085	COG2204	response regulator
LUZ17_03110	COG2972	Histidine kinase
LUZ17_03125	COG0531	amino acid
LUZ17_03145	COG3590	peptidase
LUZ17_03160	COG0667	Aldo Keto reductase
LUZ17_03175	COG3384	dioxygenase
LUZ17_03185	COG1573	uracil-dna glycosylase
LUZ17_03195	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
LUZ17_03205	COG0025	NhaP-type Na H and K H
LUZ17_03210	COG1131	(ABC) transporter
LUZ17_03215	COG0842	Transport permease protein
LUZ17_03235	COG1404	Belongs to the peptidase S8 family
LUZ17_03250	COG0745	RESPONSE REGULATOR receiver
LUZ17_03300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LUZ17_03325	COG2202	Pas domain
LUZ17_03325	COG2205	protein histidine kinase activity
LUZ17_03355	COG2813	Specifically methylates the guanine in position
LUZ17_03360	COG1187	pseudouridine synthase activity
LUZ17_03365	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LUZ17_03400	COG0697	spore germination
LUZ17_03410	COG2011	ABC-type metal ion transport system permease component
LUZ17_03440	COG0508	dehydrogenase complex catalyzes the overall conversion of
LUZ17_03450	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LUZ17_03470	COG0356	it plays a direct role in the translocation of protons across the membrane
LUZ17_03480	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LUZ17_03490	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LUZ17_03495	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LUZ17_03500	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LUZ17_03505	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LUZ17_03555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LUZ17_03560	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LUZ17_03615	COG0339	signal peptide processing
LUZ17_03650	COG1956	GAF domain-containing protein
LUZ17_03655	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LUZ17_03665	COG0720	synthase
LUZ17_03670	COG0513	Belongs to the DEAD box helicase family
LUZ17_03680	COG0625	glutathione transferase activity
LUZ17_03710	COG0626	cystathionine gamma-synthase activity
LUZ17_03750	COG3328	transposase activity
LUZ17_03775	COG2086	electron transfer activity
LUZ17_03800	COG0662	Cupin 2, conserved barrel domain protein
LUZ17_03800	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
LUZ17_03805	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LUZ17_03840	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LUZ17_03840	COG3218	ABC-type transport auxiliary lipoprotein component
LUZ17_03845	COG1127	ABC transporter
LUZ17_03850	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LUZ17_03865	COG0442	prolyl-tRNA aminoacylation
LUZ17_03875	COG1183	phosphatidylcholine synthase activity
LUZ17_03900	COG3039	Transposase
LUZ17_03955	COG0525	valine-tRNA ligase activity
LUZ17_03970	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LUZ17_03980	COG0795	lipopolysaccharide-transporting ATPase activity
LUZ17_03995	COG4974	Belongs to the 'phage' integrase family
LUZ17_04000	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LUZ17_04005	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LUZ17_04005	COG0047	phosphoribosylformylglycinamidine synthase activity
LUZ17_04010	COG5295	Hep Hag repeat protein
LUZ17_04030	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LUZ17_04040	COG1459	type II secretion system
LUZ17_04045	COG2165	general secretion pathway protein
LUZ17_04050	COG4970	Tfp pilus assembly protein FimT
LUZ17_04055	COG2165	general secretion pathway protein
LUZ17_04060	COG4795	General secretion pathway protein
LUZ17_04065	COG3156	type II secretion system protein K
LUZ17_04070	COG3166	PFAM Fimbrial assembly family protein
LUZ17_04085	COG1450	Type ii and iii secretion system protein
LUZ17_04100	COG2188	Transcriptional regulator
LUZ17_04150	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LUZ17_04155	COG1518	maintenance of DNA repeat elements
LUZ17_04195	COG1399	metal-binding, possibly nucleic acid-binding protein
LUZ17_04220	COG1028	Short-chain dehydrogenase reductase Sdr
LUZ17_04225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LUZ17_04235	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LUZ17_04240	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LUZ17_04275	COG3829	transcription factor binding
LUZ17_04355	COG2826	transposase and inactivated derivatives, IS30 family
LUZ17_04365	COG0678	peroxiredoxin activity
LUZ17_04385	COG0330	HflC and HflK could
LUZ17_04390	COG0330	HflC and HflK could
LUZ17_04405	COG0308	aminopeptidase N
LUZ17_04455	COG1560	Kdo2-lipid A biosynthetic process
LUZ17_04460	COG1519	Transferase
LUZ17_04465	COG1538	Outer membrane efflux protein
LUZ17_04470	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LUZ17_04500	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LUZ17_04505	COG0066	3-isopropylmalate dehydratase activity
LUZ17_04540	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LUZ17_04550	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LUZ17_04555	COG3710	Transcriptional regulator
LUZ17_04580	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LUZ17_04600	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
LUZ17_04630	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LUZ17_04640	COG3781	membrane
LUZ17_04655	COG0625	glutathione transferase activity
LUZ17_04665	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LUZ17_04670	COG1217	gtp-binding protein TYPA
LUZ17_04690	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
LUZ17_04820	COG3039	Transposase
LUZ17_04840	COG0584	glycerophosphoryl diester phosphodiesterase
LUZ17_04865	COG0473	3-isopropylmalate dehydrogenase activity
LUZ17_04915	COG0544	peptidyl-prolyl cis-trans isomerase activity
LUZ17_04955	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LUZ17_04980	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LUZ17_04990	COG0631	protein serine/threonine phosphatase activity
LUZ17_05065	COG0582	viral genome integration into host DNA
LUZ17_05075	COG0859	PFAM glycosyl transferase family 9
LUZ17_05080	COG3642	lipopolysaccharide core region biosynthetic process
LUZ17_05085	COG1234	tRNA 3'-trailer cleavage
LUZ17_05090	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LUZ17_05100	COG0315	cyclic pyranopterin monophosphate synthase activity
LUZ17_05105	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LUZ17_05110	COG0314	molybdopterin synthase activity
LUZ17_05140	COG0537	adenosine 5'-monophosphoramidase activity
LUZ17_05160	COG0714	Associated with various cellular activities
LUZ17_05180	COG0242	peptide deformylase activity
LUZ17_05225	COG3039	Transposase
LUZ17_05250	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LUZ17_05255	COG0726	polysaccharide deacetylase
LUZ17_05305	COG2211	Major facilitator Superfamily
LUZ17_05315	COG1609	Transcriptional regulator
LUZ17_05320	COG1028	Short-chain dehydrogenase reductase Sdr
LUZ17_05325	COG2851	Citrate transporter
LUZ17_05340	COG0642	Histidine kinase
LUZ17_05350	COG2197	response regulator
LUZ17_05370	COG0583	DNA-binding transcription factor activity
LUZ17_05385	COG4191	Histidine kinase
LUZ17_05405	COG0280	phosphate acetyltransferase
LUZ17_05405	COG0281	malic enzyme
LUZ17_05435	COG0352	thiamine-phosphate diphosphorylase activity
LUZ17_05440	COG1773	rubredoxin
LUZ17_05445	COG2912	Transglutaminase-like superfamily
LUZ17_05465	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LUZ17_05490	COG0006	proline dipeptidase activity
LUZ17_05530	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LUZ17_05545	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LUZ17_05550	COG1561	YicC-like family, N-terminal region
LUZ17_05575	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LUZ17_05585	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LUZ17_05615	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LUZ17_05665	COG0714	Associated with various cellular activities
LUZ17_05685	COG2304	oxidoreductase activity
LUZ17_05705	COG1301	dicarboxylic acid transport
LUZ17_05710	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LUZ17_05720	COG0739	heme binding
LUZ17_05725	COG1376	ErfK ybiS ycfS ynhG family protein
LUZ17_05750	COG1022	Amp-dependent synthetase and ligase
LUZ17_05760	COG1028	Short-chain dehydrogenase reductase Sdr
LUZ17_05775	COG0642	Histidine kinase
LUZ17_05795	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
LUZ17_05800	COG4149	molybdate abc transporter
LUZ17_05805	COG0725	ABC transporter, periplasmic molybdate-binding protein
LUZ17_05810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LUZ17_05810	COG3453	Protein conserved in bacteria
LUZ17_05840	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LUZ17_05860	COG2205	protein histidine kinase activity
LUZ17_05865	COG0745	RESPONSE REGULATOR receiver
LUZ17_05910	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LUZ17_05915	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LUZ17_05960	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LUZ17_06010	COG2201	protein-glutamate methylesterase activity
LUZ17_06040	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LUZ17_06050	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LUZ17_06055	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LUZ17_06070	COG1842	Phage shock protein A
LUZ17_06095	COG0754	glutathionylspermidine amidase activity
LUZ17_06155	COG0531	amino acid
LUZ17_06160	COG2197	response regulator
LUZ17_06175	COG1113	amino acid transport
LUZ17_06190	COG1271	oxidase subunit
LUZ17_06195	COG1294	oxidase, subunit
LUZ17_06205	COG2239	Acts as a magnesium transporter
LUZ17_06210	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LUZ17_06215	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LUZ17_06225	COG1660	Displays ATPase and GTPase activities
LUZ17_06230	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LUZ17_06235	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LUZ17_06250	COG1137	ATPase activity
LUZ17_06255	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
LUZ17_06265	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LUZ17_06275	COG0271	Belongs to the BolA IbaG family
LUZ17_06280	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LUZ17_06300	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LUZ17_06315	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LUZ17_06325	COG0628	permease
LUZ17_06335	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LUZ17_06340	COG3178	'Phosphotransferase
LUZ17_06355	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LUZ17_06360	COG1555	photosystem II stabilization
LUZ17_06400	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LUZ17_06410	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LUZ17_06430	COG0228	four-way junction DNA binding
LUZ17_06435	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LUZ17_06440	COG0336	Belongs to the RNA methyltransferase TrmD family
LUZ17_06455	COG0534	Mate efflux family protein
LUZ17_06490	COG0542	response to heat
LUZ17_06525	COG4206	TonB-dependent receptor
LUZ17_06590	COG0019	diaminopimelate decarboxylase activity
LUZ17_06600	COG2814	Major facilitator Superfamily
LUZ17_06605	COG4264	IucA IucC family
LUZ17_06615	COG4772	TonB-dependent receptor
LUZ17_06630	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LUZ17_06630	COG4651	solute:proton antiporter activity
LUZ17_06665	COG0488	(ABC) transporter
LUZ17_06690	COG0657	acetylesterase activity
LUZ17_06690	COG2755	lipolytic protein G-D-S-L family
LUZ17_06720	COG2207	Transcriptional regulator
LUZ17_06725	COG0326	Molecular chaperone. Has ATPase activity
LUZ17_06750	COG3328	transposase activity
LUZ17_06755	COG0174	glutamine synthetase
LUZ17_06760	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
LUZ17_06770	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LUZ17_06785	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LUZ17_06820	COG2146	nitrite reductase [NAD(P)H] activity
LUZ17_06830	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LUZ17_06835	COG0719	Fe-S assembly protein
LUZ17_06840	COG0396	ATPase activity
LUZ17_06845	COG0719	Fe-S assembly protein
LUZ17_06850	COG1959	2 iron, 2 sulfur cluster binding
LUZ17_06910	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LUZ17_06935	COG0519	Catalyzes the synthesis of GMP from XMP
LUZ17_06950	COG1678	Uncharacterized ACR, COG1678
LUZ17_06955	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LUZ17_06970	COG1764	response to oxidative stress
LUZ17_06980	COG0384	phenazine biosynthesis protein PhzF
LUZ17_06990	COG0527	aspartate kinase activity
LUZ17_07015	COG0142	geranyltranstransferase activity
LUZ17_07020	COG0629	single-stranded DNA binding
LUZ17_07025	COG2203	Gaf domain
LUZ17_07025	COG4251	negative regulation of phosphorylation
LUZ17_07025	COG3706	GGDEF domain
LUZ17_07025	COG5001	Diguanylate cyclase
LUZ17_07060	COG2879	small protein
LUZ17_07065	COG1966	Carbon starvation protein
LUZ17_07070	COG1741	Belongs to the pirin family
LUZ17_07160	COG1741	Belongs to the pirin family
LUZ17_07170	COG1515	deoxyribonuclease V activity
LUZ17_07190	COG3590	peptidase
LUZ17_07205	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LUZ17_07210	COG2199	diguanylate cyclase activity
LUZ17_07210	COG2200	EAL domain
LUZ17_07210	COG2202	Pas domain
LUZ17_07215	COG0835	chemotaxis
LUZ17_07220	COG0840	transmembrane signaling receptor activity
LUZ17_07225	COG2198	Histidine kinase
LUZ17_07225	COG0643	Histidine kinase
LUZ17_07240	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LUZ17_07250	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LUZ17_07350	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LUZ17_07355	COG0735	belongs to the Fur family
LUZ17_07415	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LUZ17_07420	COG0084	hydrolase, TatD family'
LUZ17_07435	COG1960	acyl-CoA dehydrogenase activity
LUZ17_07450	COG0367	asparagine synthase
LUZ17_07460	COG0305	Participates in initiation and elongation during chromosome replication
LUZ17_07465	COG0415	Belongs to the DNA photolyase family
LUZ17_07585	COG5001	Diguanylate cyclase
LUZ17_07585	COG5002	protein histidine kinase activity
LUZ17_07590	COG1187	pseudouridine synthase activity
LUZ17_07610	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LUZ17_07620	COG0475	glutathione-regulated potassium exporter activity
LUZ17_07625	COG5002	protein histidine kinase activity
LUZ17_07625	COG5000	phosphorelay sensor kinase activity
LUZ17_07630	COG0745	RESPONSE REGULATOR receiver
LUZ17_07660	COG1132	(ABC) transporter
LUZ17_07690	COG3039	Transposase
LUZ17_07715	COG3039	Transposase
LUZ17_07750	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LUZ17_07760	COG4969	Belongs to the N-Me-Phe pilin family
LUZ17_07765	COG2194	sulfuric ester hydrolase activity
LUZ17_07785	COG2184	nucleotidyltransferase activity
LUZ17_07810	COG0045	succinate-CoA ligase (ADP-forming) activity
LUZ17_07815	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LUZ17_07830	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LUZ17_07830	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LUZ17_07835	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LUZ17_07840	COG0564	pseudouridine synthase activity
LUZ17_07865	COG3387	PFAM Glycoside hydrolase 15-related
LUZ17_07870	COG1877	trehalose-phosphatase activity
LUZ17_07910	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
LUZ17_07940	COG1946	Acyl-CoA thioesterase
LUZ17_07955	COG0824	Thioesterase
LUZ17_07960	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LUZ17_07970	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LUZ17_07975	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LUZ17_07980	COG0268	Binds directly to 16S ribosomal RNA
LUZ17_07985	COG0728	peptidoglycan biosynthetic process
LUZ17_07990	COG0196	riboflavin kinase activity
LUZ17_08000	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LUZ17_08005	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LUZ17_08020	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LUZ17_08025	COG1845	cytochrome c oxidase, subunit III
LUZ17_08030	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LUZ17_08050	COG3209	COG3209 Rhs family protein
LUZ17_08165	COG0632	four-way junction helicase activity
LUZ17_08175	COG2255	four-way junction helicase activity
LUZ17_08180	COG0824	Thioesterase
LUZ17_08190	COG0848	biopolymer transport protein
LUZ17_08205	COG2885	chlorophyll binding
LUZ17_08215	COG0602	queuosine metabolic process
LUZ17_08220	COG1187	pseudouridine synthase activity
LUZ17_08275	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LUZ17_08300	COG0514	ATP-dependent DNA helicase (RecQ)
LUZ17_08305	COG0783	Belongs to the Dps family
LUZ17_08310	COG1643	Atp-dependent helicase
LUZ17_08365	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LUZ17_08375	COG1215	transferase activity, transferring glycosyl groups
LUZ17_08380	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LUZ17_08390	COG1199	ATP-dependent helicase activity
LUZ17_08400	COG1397	ADP-ribosylglycohydrolase
LUZ17_08410	COG0189	ligase activity
LUZ17_08425	COG0835	chemotaxis
LUZ17_08430	COG0840	transmembrane signaling receptor activity
LUZ17_08435	COG2198	Histidine kinase
LUZ17_08435	COG0784	Response regulator, receiver
LUZ17_08435	COG0643	Histidine kinase
LUZ17_08460	COG2304	oxidoreductase activity
LUZ17_08465	COG2304	oxidoreductase activity
LUZ17_08475	COG1446	asparaginase
LUZ17_08480	COG3142	Participates in the control of copper homeostasis
LUZ17_08530	COG3537	Alpha-1,2-mannosidase
LUZ17_08605	COG1472	Belongs to the glycosyl hydrolase 3 family
LUZ17_08615	COG3525	Glycosyl hydrolase, family 20, catalytic domain
LUZ17_08625	COG1388	LysM domain
LUZ17_08625	COG3858	chitin binding
LUZ17_08640	COG0837	glucose binding
LUZ17_08645	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LUZ17_08655	COG0494	nUDIX hydrolase
LUZ17_08665	COG3956	TIGRFAM MazG family protein
LUZ17_08680	COG0330	HflC and HflK could
LUZ17_08695	COG0509	glycine decarboxylation via glycine cleavage system
LUZ17_08730	COG1960	acyl-CoA dehydrogenase activity
LUZ17_08740	COG1309	transcriptional regulator
LUZ17_08745	COG4771	TonB-dependent receptor
LUZ17_08755	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LUZ17_08765	COG0463	Glycosyl transferase, family 2
LUZ17_08790	COG1272	protein, Hemolysin III
LUZ17_08800	COG0739	heme binding
LUZ17_08805	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LUZ17_08810	COG0626	cystathionine gamma-synthase activity
LUZ17_08820	COG1760	l-serine dehydratase
LUZ17_08835	COG2353	YceI-like domain
LUZ17_08845	COG2353	YceI-like domain
LUZ17_08915	COG1960	acyl-CoA dehydrogenase activity
LUZ17_08920	COG1024	Enoyl-CoA hydratase
LUZ17_08940	COG1250	3-hydroxyacyl-CoA dehydrogenase
LUZ17_08940	COG1024	Enoyl-CoA hydratase
LUZ17_08955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LUZ17_08985	COG1381	Involved in DNA repair and RecF pathway recombination
LUZ17_09000	COG2954	triphosphatase activity
LUZ17_09015	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LUZ17_09020	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
LUZ17_09025	COG3046	protein related to deoxyribodipyrimidine photolyase
LUZ17_09035	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LUZ17_09040	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LUZ17_09045	COG1278	Cold shock
LUZ17_09075	COG1201	RNA secondary structure unwinding
LUZ17_09080	COG1793	dna ligase
LUZ17_09090	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
LUZ17_09090	COG1793	dna ligase
LUZ17_09120	COG0183	Belongs to the thiolase family
LUZ17_09160	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LUZ17_09195	COG1047	Peptidyl-prolyl cis-trans
LUZ17_09210	COG2824	Alkylphosphonate utilization operon protein PhnA
LUZ17_09220	COG1902	pentaerythritol trinitrate reductase activity
LUZ17_09225	COG2814	Major facilitator Superfamily
LUZ17_09270	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LUZ17_09270	COG0392	lysyltransferase activity
LUZ17_09280	COG0251	oxidation-reduction process
LUZ17_09285	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LUZ17_09300	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LUZ17_09325	COG1595	DNA-templated transcription, initiation
LUZ17_09345	COG2878	Part of a membrane complex involved in electron transport
LUZ17_09355	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LUZ17_09355	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LUZ17_09375	COG0833	amino acid
LUZ17_09380	COG2040	homocysteine
LUZ17_09395	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LUZ17_09430	COG0529	Catalyzes the synthesis of activated sulfate
LUZ17_09430	COG2895	sulfate adenylyltransferase (ATP) activity
LUZ17_09475	COG1981	membrane
LUZ17_09500	COG1131	(ABC) transporter
LUZ17_09505	COG4771	TonB-dependent receptor
LUZ17_09515	COG0825	malonyl-CoA metabolic process
LUZ17_09535	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LUZ17_09540	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LUZ17_09560	COG0750	zinc metalloprotease
LUZ17_09570	COG0575	Belongs to the CDS family
LUZ17_09580	COG0233	cytoplasmic translational termination
LUZ17_09595	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LUZ17_09655	COG1393	Belongs to the ArsC family
LUZ17_09670	COG0367	asparagine synthase
LUZ17_09680	COG4774	siderophore transport
LUZ17_09715	COG1566	PFAM secretion protein HlyD family protein
LUZ17_09720	COG2814	Major facilitator Superfamily
LUZ17_09765	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LUZ17_09775	COG1960	acyl-CoA dehydrogenase activity
LUZ17_09800	COG2914	Belongs to the UPF0125 (RnfH) family
LUZ17_09805	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LUZ17_09815	COG0497	DNA recombination
LUZ17_09825	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LUZ17_09830	COG0443	Heat shock 70 kDa protein
LUZ17_09835	COG0484	heat shock protein binding
LUZ17_09840	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
LUZ17_09845	COG1605	Chorismate mutase
LUZ17_09845	COG0287	Prephenate dehydrogenase
LUZ17_09870	COG1132	(ABC) transporter
LUZ17_09905	COG2850	peptidyl-arginine hydroxylation
LUZ17_09980	COG1131	(ABC) transporter
LUZ17_09985	COG1725	Transcriptional regulator
LUZ17_09995	COG0386	Belongs to the glutathione peroxidase family
LUZ17_10010	COG2900	Belongs to the SlyX family
LUZ17_10025	COG1609	Transcriptional regulator
LUZ17_10035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LUZ17_10045	COG1410	methionine synthase
LUZ17_10045	COG0646	methionine synthase
LUZ17_10050	COG0646	methionine synthase
LUZ17_10050	COG1410	methionine synthase
LUZ17_10055	COG2226	methyltransferase
LUZ17_10060	COG1960	acyl-CoA dehydrogenase activity
LUZ17_10085	COG0557	exoribonuclease II activity
LUZ17_10105	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LUZ17_10115	COG3039	Transposase
LUZ17_10135	COG3328	transposase activity
LUZ17_10160	COG3039	Transposase
LUZ17_10210	COG3039	Transposase
LUZ17_10260	COG3039	Transposase
LUZ17_10270	COG0583	DNA-binding transcription factor activity
LUZ17_10320	COG2201	protein-glutamate methylesterase activity
LUZ17_10350	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
LUZ17_10360	COG0531	amino acid
LUZ17_10365	COG0531	amino acid
LUZ17_10375	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LUZ17_10380	COG0277	FAD linked oxidase domain protein
LUZ17_10445	COG0436	Aminotransferase
LUZ17_10470	COG1187	pseudouridine synthase activity
LUZ17_10475	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LUZ17_10480	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LUZ17_10485	COG2350	Protein conserved in bacteria
LUZ17_10515	COG1175	transmembrane transport
LUZ17_10520	COG0395	ABC-type sugar transport system, permease component
LUZ17_10545	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LUZ17_10555	COG2957	Belongs to the agmatine deiminase family
LUZ17_10570	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LUZ17_10575	COG0539	negative regulation of cytoplasmic translation
LUZ17_10580	COG0776	regulation of translation
LUZ17_10590	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
LUZ17_10595	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LUZ17_10605	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LUZ17_10625	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LUZ17_10640	COG3002	Belongs to the UPF0753 family
LUZ17_10645	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LUZ17_10650	COG0583	DNA-binding transcription factor activity
LUZ17_10665	COG1028	Short-chain dehydrogenase reductase Sdr
LUZ17_10680	COG0583	DNA-binding transcription factor activity
LUZ17_10705	COG1914	H( )-stimulated, divalent metal cation uptake system
LUZ17_10725	COG0668	transmembrane transport
LUZ17_10775	COG1028	Short-chain dehydrogenase reductase Sdr
LUZ17_10780	COG1183	phosphatidylcholine synthase activity
LUZ17_10790	COG3243	poly(R)-hydroxyalkanoic acid synthase
LUZ17_10805	COG0723	plastoquinol--plastocyanin reductase activity
LUZ17_10805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LUZ17_10815	COG2183	response to ionizing radiation
LUZ17_10830	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
LUZ17_10845	COG0671	phosphoesterase, PA-phosphatase related
LUZ17_10870	COG0697	spore germination
LUZ17_10900	COG1012	belongs to the aldehyde dehydrogenase family
LUZ17_10935	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LUZ17_10950	COG0124	histidyl-tRNA synthetase
LUZ17_10970	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LUZ17_10985	COG0131	Imidazoleglycerol-phosphate dehydratase
LUZ17_10985	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LUZ17_10995	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LUZ17_11005	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LUZ17_11005	COG0140	phosphoribosyl-ATP diphosphatase activity
LUZ17_11235	COG2201	protein-glutamate methylesterase activity
LUZ17_11260	COG3039	Transposase
LUZ17_11280	COG3328	transposase activity
LUZ17_11315	COG0322	excinuclease ABC activity
LUZ17_11325	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LUZ17_11335	COG1663	tetraacyldisaccharide 4'-kinase activity
LUZ17_11350	COG0811	peptide transport
LUZ17_11375	COG4591	ABC-type transport system involved in lipoprotein release permease component
LUZ17_11390	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LUZ17_11405	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LUZ17_11420	COG0354	folic acid binding
LUZ17_11435	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LUZ17_11445	COG0363	glucosamine-6-phosphate deaminase activity
LUZ17_11450	COG0129	dihydroxy-acid dehydratase activity
LUZ17_11455	COG0800	Aldolase
LUZ17_11485	COG5002	protein histidine kinase activity
LUZ17_11485	COG0784	Response regulator, receiver
LUZ17_11485	COG2205	protein histidine kinase activity
LUZ17_11565	COG0386	Belongs to the glutathione peroxidase family
LUZ17_11650	COG2203	Gaf domain
LUZ17_11650	COG3706	GGDEF domain
LUZ17_11650	COG4251	negative regulation of phosphorylation
LUZ17_11650	COG5001	Diguanylate cyclase
LUZ17_11665	COG1472	Belongs to the glycosyl hydrolase 3 family
LUZ17_11695	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LUZ17_11710	COG0617	tRNA 3'-terminal CCA addition
LUZ17_11720	COG1469	GTP cyclohydrolase I activity
LUZ17_11725	COG0860	N-Acetylmuramoyl-L-alanine amidase
LUZ17_11770	COG4566	intracellular signal transduction
LUZ17_11800	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LUZ17_11805	COG1605	Chorismate mutase
LUZ17_11805	COG0077	Prephenate dehydratase
LUZ17_11815	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LUZ17_11855	COG1228	amidohydrolase
LUZ17_11860	COG2986	histidine ammonia-lyase
LUZ17_11870	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LUZ17_11895	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
LUZ17_11910	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
LUZ17_11930	COG3115	cell septum assembly
LUZ17_11940	COG0359	binds to the 23S rRNA
LUZ17_11950	COG0360	Binds together with S18 to 16S ribosomal RNA
LUZ17_11955	COG0316	Belongs to the HesB IscA family
LUZ17_11985	COG0288	reversible hydration of carbon dioxide
LUZ17_12010	COG2925	Exonuclease
LUZ17_12020	COG0667	Aldo Keto reductase
LUZ17_12045	COG0116	Belongs to the methyltransferase superfamily
LUZ17_12045	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LUZ17_12090	COG0494	nUDIX hydrolase
LUZ17_12105	COG1024	Enoyl-CoA hydratase
LUZ17_12115	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LUZ17_12135	COG3039	Transposase
LUZ17_12175	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LUZ17_12180	COG0573	inorganic phosphate transmembrane transporter activity
LUZ17_12195	COG0704	Plays a role in the regulation of phosphate uptake
LUZ17_12205	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LUZ17_12220	COG3328	transposase activity
LUZ17_12240	COG3039	Transposase
LUZ17_12250	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LUZ17_12255	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LUZ17_12260	COG1862	Preprotein translocase
LUZ17_12265	COG0343	queuine tRNA-ribosyltransferase activity
LUZ17_12340	COG0405	Gamma-glutamyltransferase
LUZ17_12345	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LUZ17_12355	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LUZ17_12360	COG0742	ribosomal rna small subunit methyltransferase
LUZ17_12380	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LUZ17_12415	COG3039	Transposase
LUZ17_12445	COG0303	'Molybdopterin
LUZ17_12455	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LUZ17_12465	COG1426	Protein conserved in bacteria
LUZ17_12475	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LUZ17_12490	COG1024	Enoyl-CoA hydratase
LUZ17_12490	COG1250	3-hydroxyacyl-CoA dehydrogenase
LUZ17_12495	COG0183	Belongs to the thiolase family
LUZ17_12500	COG0038	chloride channel
LUZ17_12520	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LUZ17_12540	COG1674	ftsk spoiiie
LUZ17_12545	COG0492	ferredoxin-NADP+ reductase activity
LUZ17_12580	COG0542	response to heat
LUZ17_12595	COG0482	sulfurtransferase activity
LUZ17_12620	COG5001	Diguanylate cyclase
LUZ17_12625	COG4585	Histidine kinase
LUZ17_12635	COG5002	protein histidine kinase activity
LUZ17_12655	COG0835	chemotaxis
LUZ17_12655	COG0784	Response regulator, receiver
LUZ17_12665	COG1558	bacterial-type flagellum-dependent cell motility
LUZ17_12670	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
LUZ17_12680	COG4787	bacterial-type flagellum-dependent cell motility
LUZ17_12715	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LUZ17_12720	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LUZ17_12755	COG2201	protein-glutamate methylesterase activity
LUZ17_12775	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LUZ17_12785	COG1028	Short-chain dehydrogenase reductase Sdr
LUZ17_12815	COG1677	Flagellar hook-basal body complex protein FliE
LUZ17_12865	COG3190	flagellar
LUZ17_12880	COG1684	flagellar biosynthetic protein fliR
LUZ17_12935	COG0784	Response regulator, receiver
LUZ17_12935	COG0643	Histidine kinase
LUZ17_12935	COG2198	Histidine kinase
LUZ17_12965	COG3039	Transposase
LUZ17_12975	COG3209	COG3209 Rhs family protein
LUZ17_12985	COG3039	Transposase
LUZ17_12995	COG3039	Transposase
LUZ17_13005	COG3039	Transposase
LUZ17_13085	COG3039	Transposase
LUZ17_13095	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LUZ17_13100	COG4988	ABC transporter
LUZ17_13115	COG3039	Transposase
LUZ17_13150	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LUZ17_13170	COG0165	Argininosuccinate lyase
LUZ17_13185	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LUZ17_13190	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LUZ17_13200	COG0137	argininosuccinate synthase activity
LUZ17_13205	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LUZ17_13220	COG2166	iron-sulfur cluster assembly
LUZ17_13245	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LUZ17_13280	COG3039	Transposase
LUZ17_13290	COG4677	pectinesterase activity
LUZ17_13315	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LUZ17_13320	COG0402	S-adenosylhomocysteine deaminase activity
LUZ17_13335	COG1509	lysine 2,3-aminomutase activity
LUZ17_13340	COG3300	MHYT domain
LUZ17_13340	COG5001	Diguanylate cyclase
LUZ17_13355	COG0483	inositol monophosphate 1-phosphatase activity
LUZ17_13360	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LUZ17_13380	COG0488	(ABC) transporter
LUZ17_13385	COG0513	Belongs to the DEAD box helicase family
LUZ17_13405	COG0625	glutathione transferase activity
LUZ17_13415	COG1671	Belongs to the UPF0178 family
LUZ17_13420	COG4681	YaeQ
LUZ17_13425	COG2081	HI0933 family
LUZ17_13445	COG1028	Short-chain dehydrogenase reductase Sdr
LUZ17_13465	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LUZ17_13470	COG0860	N-Acetylmuramoyl-L-alanine amidase
LUZ17_13475	COG0802	atpase or kinase
LUZ17_13480	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LUZ17_13480	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LUZ17_13485	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LUZ17_13510	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LUZ17_13575	COG3328	transposase activity
LUZ17_13585	COG2094	Belongs to the DNA glycosylase MPG family
LUZ17_13610	COG2969	positive regulation of protein catabolic process
LUZ17_13615	COG0625	glutathione transferase activity
LUZ17_13620	COG2857	Cytochrome c1
LUZ17_13625	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LUZ17_13630	COG0723	plastoquinol--plastocyanin reductase activity
LUZ17_13635	COG0741	lytic transglycosylase activity
LUZ17_13665	COG1702	phosphate starvation-inducible protein PhoH
LUZ17_13685	COG4535	Mg2 and Co2 transporter CorC
LUZ17_13700	COG1012	belongs to the aldehyde dehydrogenase family
LUZ17_13720	COG3842	ATPase activity
LUZ17_13755	COG0174	glutamine synthetase
LUZ17_13760	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LUZ17_13770	COG0477	Major facilitator Superfamily
LUZ17_13780	COG0243	molybdopterin cofactor binding
LUZ17_13790	COG2223	nitrite transmembrane transporter activity
LUZ17_13795	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LUZ17_13800	COG1121	(ABC) transporter
LUZ17_13810	COG2733	membrane
LUZ17_13815	COG5002	protein histidine kinase activity
LUZ17_13815	COG2205	protein histidine kinase activity
LUZ17_13815	COG0784	Response regulator, receiver
LUZ17_13825	COG3039	Transposase
LUZ17_13830	COG2902	Dehydrogenase
LUZ17_13840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LUZ17_13845	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LUZ17_13865	COG1609	Transcriptional regulator
LUZ17_13870	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LUZ17_13870	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LUZ17_13875	COG1105	Belongs to the carbohydrate kinase PfkB family
LUZ17_13880	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LUZ17_13880	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LUZ17_13890	COG3039	Transposase
LUZ17_13970	COG3409	Peptidoglycan-binding domain 1 protein
LUZ17_13970	COG3501	Rhs element vgr protein
LUZ17_13990	COG3409	Peptidoglycan-binding domain 1 protein
LUZ17_13990	COG3501	Rhs element vgr protein
LUZ17_14035	COG3039	Transposase
LUZ17_14060	COG4771	TonB-dependent receptor
LUZ17_14070	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LUZ17_14090	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LUZ17_14095	COG1360	Flagellar Motor Protein
LUZ17_14105	COG0835	chemotaxis
LUZ17_14115	COG0745	RESPONSE REGULATOR receiver
LUZ17_14145	COG0840	transmembrane signaling receptor activity
LUZ17_14155	COG0840	transmembrane signaling receptor activity
LUZ17_14165	COG0840	transmembrane signaling receptor activity
LUZ17_14170	COG0840	transmembrane signaling receptor activity
LUZ17_14175	COG0840	transmembrane signaling receptor activity
LUZ17_14180	COG0840	transmembrane signaling receptor activity
LUZ17_14195	COG0835	chemotaxis
LUZ17_14215	COG0840	transmembrane signaling receptor activity
LUZ17_14245	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LUZ17_14275	COG0318	PFAM AMP-dependent synthetase and ligase
LUZ17_14280	COG1024	Enoyl-CoA hydratase
LUZ17_14285	COG2198	Histidine kinase
LUZ17_14285	COG2205	protein histidine kinase activity
LUZ17_14285	COG0784	Response regulator, receiver
LUZ17_14335	COG3039	Transposase
LUZ17_14345	COG3039	Transposase
LUZ17_14355	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LUZ17_14365	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LUZ17_14370	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LUZ17_14380	COG0505	Belongs to the CarA family
LUZ17_14385	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LUZ17_14395	COG2258	MOSC domain
LUZ17_14400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LUZ17_14445	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LUZ17_14465	COG0477	Major facilitator Superfamily
LUZ17_14475	COG1070	Carbohydrate kinase
LUZ17_14485	COG1501	Belongs to the glycosyl hydrolase 31 family
LUZ17_14500	COG0800	Aldolase
LUZ17_14505	COG4948	Mandelate Racemase Muconate Lactonizing
LUZ17_14515	COG3734	2-keto-3-deoxy-galactonokinase
LUZ17_14520	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LUZ17_14530	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LUZ17_14545	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LUZ17_14550	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LUZ17_14560	COG0351	phosphomethylpyrimidine kinase
LUZ17_14585	COG0583	DNA-binding transcription factor activity
LUZ17_14590	COG1741	Belongs to the pirin family
LUZ17_14605	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LUZ17_14610	COG0305	Participates in initiation and elongation during chromosome replication
LUZ17_14630	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LUZ17_14635	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LUZ17_14640	COG2137	regulation of response to DNA damage stimulus
LUZ17_14645	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LUZ17_14660	COG1546	Belongs to the CinA family
LUZ17_14665	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LUZ17_14680	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LUZ17_14690	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
LUZ17_14695	COG1534	Rna-binding protein
LUZ17_14710	COG1238	metal cluster binding
LUZ17_14715	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LUZ17_14720	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LUZ17_14725	COG2840	Smr protein MutS2
LUZ17_14735	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LUZ17_14750	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LUZ17_14755	COG0148	phosphopyruvate hydratase activity
LUZ17_14765	COG2877	3-deoxy-8-phosphooctulonate synthase activity
LUZ17_14770	COG0504	CTP synthase activity
LUZ17_14795	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LUZ17_14800	COG0306	phosphate transporter
LUZ17_14810	COG1253	flavin adenine dinucleotide binding
LUZ17_14825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LUZ17_14835	COG0477	Major facilitator Superfamily
LUZ17_14845	COG1132	(ABC) transporter
LUZ17_14850	COG1136	(ABC) transporter
LUZ17_14870	COG0438	transferase activity, transferring glycosyl groups
LUZ17_14880	COG2264	protein methyltransferase activity
LUZ17_14910	COG2244	polysaccharide biosynthetic process
LUZ17_14960	COG1595	DNA-templated transcription, initiation
LUZ17_14975	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LUZ17_14995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LUZ17_15040	COG2201	protein-glutamate methylesterase activity
LUZ17_15065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LUZ17_15120	COG1858	cytochrome C peroxidase
LUZ17_15155	COG0515	serine threonine protein kinase
LUZ17_15160	COG0631	protein serine/threonine phosphatase activity
LUZ17_15265	COG3039	Transposase
LUZ17_15315	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
LUZ17_15315	COG0316	Belongs to the HesB IscA family
LUZ17_15320	COG2154	pterin-4-alpha-carbinolamine dehydratase
LUZ17_15335	COG3064	Membrane
LUZ17_15345	COG1530	ribonuclease E activity
LUZ17_15360	COG1054	Belongs to the UPF0176 family
LUZ17_15365	COG3039	Transposase
LUZ17_15385	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LUZ17_15420	COG3039	Transposase
LUZ17_15430	COG3039	Transposase
LUZ17_15460	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LUZ17_15460	COG1648	precorrin-2 dehydrogenase activity
LUZ17_15485	COG0746	molybdenum cofactor guanylyltransferase activity
LUZ17_15575	COG4206	TonB-dependent receptor
LUZ17_15605	COG0531	amino acid
LUZ17_15620	COG0006	proline dipeptidase activity
LUZ17_15630	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LUZ17_15645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LUZ17_15650	COG3938	Belongs to the proline racemase family
LUZ17_15660	COG0552	protein localization to endoplasmic reticulum
LUZ17_15680	COG4191	Histidine kinase
LUZ17_15680	COG0784	Response regulator, receiver
LUZ17_15685	COG3039	Transposase
LUZ17_15770	COG3040	lipid binding
LUZ17_15810	COG0438	transferase activity, transferring glycosyl groups
LUZ17_15820	COG0438	transferase activity, transferring glycosyl groups
LUZ17_15825	COG0438	transferase activity, transferring glycosyl groups
LUZ17_15895	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LUZ17_15930	COG0556	nucleotide-excision repair
LUZ17_15935	COG4969	Belongs to the N-Me-Phe pilin family
LUZ17_15975	COG1611	Belongs to the LOG family
LUZ17_15990	COG2095	MarC family integral membrane protein
LUZ17_16000	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LUZ17_16035	COG1185	polyribonucleotide nucleotidyltransferase activity
LUZ17_16040	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LUZ17_16060	COG0195	Participates in both transcription termination and antitermination
LUZ17_16065	COG0779	Required for maturation of 30S ribosomal subunits
LUZ17_16075	COG1007	ATP synthesis coupled electron transport
LUZ17_16105	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LUZ17_16110	COG1034	ATP synthesis coupled electron transport
LUZ17_16115	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LUZ17_16120	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
LUZ17_16125	COG0649	NAD binding
LUZ17_16130	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LUZ17_16140	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LUZ17_16155	COG0149	triose-phosphate isomerase activity
LUZ17_16200	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LUZ17_16205	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LUZ17_16230	COG0135	phosphoribosylanthranilate isomerase activity
LUZ17_16235	COG0101	tRNA pseudouridine synthase activity
LUZ17_16255	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LUZ17_16260	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LUZ17_16265	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LUZ17_16270	COG2890	protein-(glutamine-N5) methyltransferase activity
LUZ17_16310	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LUZ17_16340	COG0717	Belongs to the dCTP deaminase family
LUZ17_16345	COG0489	protein tyrosine kinase activity
LUZ17_16385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LUZ17_16390	COG2311	Membrane
LUZ17_16395	COG1047	Peptidyl-prolyl cis-trans
LUZ17_16400	COG0791	NLP P60 protein
LUZ17_16405	COG0791	NLP P60 protein
LUZ17_16430	COG1785	Belongs to the alkaline phosphatase family
LUZ17_16435	COG0037	tRNA processing
LUZ17_16440	COG1722	exodeoxyribonuclease VII activity
LUZ17_16445	COG0142	geranyltranstransferase activity
LUZ17_16470	COG0312	modulator of DNA gyrase
LUZ17_16475	COG3028	Belongs to the UPF0307 family
LUZ17_16480	COG0312	modulator of DNA gyrase
LUZ17_16490	COG3164	Protein of unknown function
LUZ17_16505	COG2968	Membrane
LUZ17_16530	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LUZ17_16555	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LUZ17_16580	COG3118	belongs to the thioredoxin family
LUZ17_16645	COG3039	Transposase
LUZ17_16650	COG3039	Transposase
LUZ17_16735	COG2022	thiamine diphosphate biosynthetic process
LUZ17_16745	COG0471	metal ion transport
LUZ17_16745	COG3273	potassium ion transport
LUZ17_16765	COG3039	Transposase
LUZ17_16780	COG1970	mechanosensitive ion channel activity
LUZ17_16800	COG2272	Belongs to the type-B carboxylesterase lipase family
LUZ17_16805	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LUZ17_16825	COG0308	aminopeptidase N
LUZ17_16830	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LUZ17_16840	COG0529	Catalyzes the synthesis of activated sulfate
LUZ17_16840	COG2895	sulfate adenylyltransferase (ATP) activity
LUZ17_16845	COG0175	sulfate reduction
LUZ17_16850	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LUZ17_16855	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LUZ17_16860	COG0175	sulfate reduction
LUZ17_16880	COG0784	Response regulator, receiver
LUZ17_16880	COG2198	Histidine kinase
LUZ17_16880	COG2205	protein histidine kinase activity
LUZ17_16930	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
LUZ17_16935	COG3588	fructose-bisphosphate aldolase
LUZ17_16940	COG0469	pyruvate kinase activity
LUZ17_16980	COG0753	catalase activity
LUZ17_17000	COG3039	Transposase
LUZ17_17025	COG2207	Transcriptional regulator
LUZ17_17025	COG1917	Cupin 2, conserved barrel domain protein
LUZ17_17045	COG1506	peptidase
LUZ17_17045	COG0823	Involved in the tonB-independent uptake of proteins
LUZ17_17065	COG3039	Transposase
LUZ17_17070	COG1297	OPT oligopeptide transporter protein
LUZ17_17165	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LUZ17_17180	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
LUZ17_17185	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
LUZ17_17190	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LUZ17_17210	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
LUZ17_17225	COG0732	type I restriction modification DNA specificity domain
LUZ17_17410	COG3179	chitinase
LUZ17_17465	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LUZ17_17530	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LUZ17_17540	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LUZ17_17635	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LUZ17_17660	COG2197	response regulator
LUZ17_17665	COG4585	Histidine kinase
LUZ17_17680	COG2894	cell division
LUZ17_17685	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
LUZ17_17695	COG0642	Histidine kinase
LUZ17_17700	COG0745	RESPONSE REGULATOR receiver
LUZ17_17705	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LUZ17_17715	COG2194	sulfuric ester hydrolase activity
LUZ17_17745	COG3551	Protein conserved in bacteria
LUZ17_17805	COG0203	ribosomal protein L17
LUZ17_17815	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LUZ17_17820	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LUZ17_17830	COG0201	protein transport
LUZ17_17840	COG1841	ribosomal large subunit assembly
LUZ17_17870	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LUZ17_17880	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LUZ17_17885	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LUZ17_17890	COG0255	Belongs to the universal ribosomal protein uL29 family
LUZ17_17895	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LUZ17_17905	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LUZ17_17920	COG0089	rRNA binding
LUZ17_17925	COG0088	Forms part of the polypeptide exit tunnel
LUZ17_17930	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LUZ17_17935	COG0051	transcription antitermination factor activity, RNA binding
LUZ17_17955	COG0049	tRNA binding
LUZ17_17960	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LUZ17_17965	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LUZ17_17970	COG0085	RNA polymerase activity
LUZ17_17975	COG0222	ribosome binding
LUZ17_17980	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LUZ17_17990	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LUZ17_17995	COG0250	Participates in transcription elongation, termination and antitermination
LUZ17_18000	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LUZ17_18030	COG0012	GTP binding
LUZ17_18035	COG0193	aminoacyl-tRNA hydrolase activity
LUZ17_18045	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LUZ17_18060	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
LUZ17_18075	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LUZ17_18085	COG0521	Mo-molybdopterin cofactor biosynthetic process
LUZ17_18105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LUZ17_18110	COG1295	ribonuclease BN
LUZ17_18140	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LUZ17_18150	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LUZ17_18175	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
LUZ17_18200	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
LUZ17_18215	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LUZ17_18215	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LUZ17_18265	COG2890	protein-(glutamine-N5) methyltransferase activity
LUZ17_18275	COG3634	alkyl hydroperoxide reductase activity
LUZ17_18280	COG0583	DNA-binding transcription factor activity
LUZ17_18285	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LUZ17_18350	COG4783	chaperone-mediated protein folding
LUZ17_18365	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LUZ17_18375	COG0438	transferase activity, transferring glycosyl groups
LUZ17_18380	COG0671	phosphoesterase, PA-phosphatase related
LUZ17_18385	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LUZ17_18405	COG2833	Protein of unknown function (DUF455)
LUZ17_18425	COG0285	dihydrofolate synthase activity
LUZ17_18435	COG0406	alpha-ribazole phosphatase activity
LUZ17_18465	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
LUZ17_18470	COG4208	sulfate ABC transporter
LUZ17_18475	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LUZ17_18480	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LUZ17_18485	COG0156	8-amino-7-oxononanoate synthase activity
LUZ17_18510	COG0604	alcohol dehydrogenase
LUZ17_18515	COG0446	pyridine nucleotide-disulphide oxidoreductase
LUZ17_18515	COG1902	pentaerythritol trinitrate reductase activity
LUZ17_18650	COG3386	PFAM SMP-30 Gluconolaconase
LUZ17_18670	COG1024	Enoyl-CoA hydratase
LUZ17_18680	COG0318	PFAM AMP-dependent synthetase and ligase
LUZ17_18685	COG0583	DNA-binding transcription factor activity
LUZ17_18725	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LUZ17_18730	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LUZ17_18740	COG2096	Adenosyltransferase
LUZ17_18745	COG0123	including yeast histone deacetylase and acetoin utilization protein
LUZ17_18760	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LUZ17_18770	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LUZ17_18775	COG2967	ApaG domain
LUZ17_18800	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LUZ17_18820	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LUZ17_18835	COG0642	Histidine kinase
LUZ17_18850	COG4181	ATPase activity
LUZ17_18860	COG2175	clavaminate synthase activity
LUZ17_18910	COG0667	Aldo Keto reductase
LUZ17_18920	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LUZ17_18925	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LUZ17_18935	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LUZ17_18950	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LUZ17_18990	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LUZ17_19045	COG3321	synthase
LUZ17_19045	COG1028	Short-chain dehydrogenase reductase Sdr
LUZ17_19045	COG0604	alcohol dehydrogenase
LUZ17_19055	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LUZ17_19075	COG0494	nUDIX hydrolase
LUZ17_19090	COG4942	peptidase
LUZ17_19090	COG1388	LysM domain
LUZ17_19100	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
LUZ17_19115	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LUZ17_19120	COG1181	Belongs to the D-alanine--D-alanine ligase family
LUZ17_19125	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LUZ17_19145	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LUZ17_19160	COG3116	cell division
LUZ17_19165	COG0275	rRNA processing
LUZ17_19200	COG0792	nuclease activity
LUZ17_19205	COG1988	membrane-bound metal-dependent
LUZ17_19210	COG0277	FAD linked oxidase domain protein
LUZ17_19215	COG0745	RESPONSE REGULATOR receiver
LUZ17_19220	COG2205	protein histidine kinase activity
LUZ17_19230	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LUZ17_19235	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
LUZ17_19255	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LUZ17_19260	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LUZ17_19265	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LUZ17_19285	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LUZ17_19285	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LUZ17_19305	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LUZ17_19325	COG0488	(ABC) transporter
LUZ17_19350	COG3791	Glutathione-dependent formaldehyde-activating
LUZ17_19375	COG2205	protein histidine kinase activity
LUZ17_19430	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LUZ17_19465	COG3039	Transposase
LUZ17_19470	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LUZ17_19480	COG3039	Transposase
LUZ17_19535	COG3039	Transposase
LUZ17_19585	COG1649	PFAM Uncharacterised BCR, COG1649
LUZ17_19585	COG0726	polysaccharide deacetylase
LUZ17_19590	COG1215	transferase activity, transferring glycosyl groups
LUZ17_19600	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LUZ17_19605	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LUZ17_19610	COG1609	Transcriptional regulator
LUZ17_19620	COG2188	Transcriptional regulator
LUZ17_19635	COG3250	beta-galactosidase activity
LUZ17_19675	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LUZ17_19680	COG4191	Histidine kinase
LUZ17_19685	COG0784	Response regulator, receiver
LUZ17_19690	COG4251	negative regulation of phosphorylation
LUZ17_19695	COG2823	Periplasmic or secreted lipoprotein
LUZ17_19700	COG0673	inositol 2-dehydrogenase activity
LUZ17_19705	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LUZ17_19740	COG1051	belongs to the nudix hydrolase family
LUZ17_19740	COG1056	cytidyltransferase-related domain
LUZ17_19780	COG2921	Belongs to the UPF0250 family
LUZ17_19795	COG1686	Belongs to the peptidase S11 family
LUZ17_19800	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LUZ17_19805	COG2951	lytic endotransglycosylase activity
LUZ17_19875	COG0772	Belongs to the SEDS family
LUZ17_19890	COG1792	Involved in formation and maintenance of cell shape
LUZ17_19895	COG1077	Cell shape determining protein MreB Mrl
LUZ17_19900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LUZ17_19905	COG3039	Transposase
LUZ17_19955	COG2199	diguanylate cyclase activity
LUZ17_19960	COG0308	aminopeptidase N
LUZ17_19990	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LUZ17_20020	COG0436	Aminotransferase
LUZ17_20035	COG1505	serine-type exopeptidase activity
LUZ17_20060	COG0181	hydroxymethylbilane synthase activity
LUZ17_20070	COG3275	phosphorelay sensor kinase activity
LUZ17_20105	COG0659	secondary active sulfate transmembrane transporter activity
LUZ17_20110	COG5297	Belongs to the glycosyl hydrolase family 6
LUZ17_20110	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LUZ17_20180	COG0598	Magnesium transport protein CorA
LUZ17_20190	COG1113	amino acid transport
LUZ17_20200	COG5297	Belongs to the glycosyl hydrolase family 6
LUZ17_20205	COG4305	rare lipoprotein A
LUZ17_20210	COG0697	spore germination
LUZ17_20270	COG4221	oxidoreductase activity
LUZ17_20300	COG0456	acetyltransferase
LUZ17_20310	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
LUZ17_20340	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LUZ17_20340	COG2111	Na H antiporter
LUZ17_20345	COG1006	Multisubunit Na H antiporter MnhC subunit
LUZ17_20350	COG0651	ATP synthesis coupled electron transport
LUZ17_20360	COG2212	antiporter activity
LUZ17_20365	COG1320	monovalent cation:proton antiporter activity
LUZ17_20375	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
LUZ17_20395	COG3104	oligopeptide transport
LUZ17_20400	COG3483	tryptophan 2,3-dioxygenase activity
LUZ17_20445	COG0183	Belongs to the thiolase family
LUZ17_20495	COG3039	Transposase
LUZ17_20525	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
LUZ17_20530	COG3023	N-Acetylmuramoyl-L-alanine amidase
LUZ17_20540	COG4948	Mandelate Racemase Muconate Lactonizing
LUZ17_20575	COG0531	amino acid
LUZ17_20610	COG4682	membrane
LUZ17_20615	COG2133	pyrroloquinoline quinone binding
LUZ17_20650	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LUZ17_20655	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LUZ17_20665	COG1610	YqeY-like protein
LUZ17_20675	COG1295	ribonuclease BN
LUZ17_20680	COG0358	DNA primase activity
LUZ17_20745	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
LUZ17_20760	COG1565	acr, cog1565
LUZ17_20760	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LUZ17_20810	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LUZ17_20815	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LUZ17_20820	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
LUZ17_20830	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
LUZ17_20835	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LUZ17_20850	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LUZ17_20910	COG3328	transposase activity
LUZ17_20920	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LUZ17_20920	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LUZ17_20930	COG1473	amidohydrolase
LUZ17_20935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LUZ17_20940	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LUZ17_20950	COG5383	Protein conserved in bacteria
LUZ17_20985	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LUZ17_20990	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
LUZ17_21005	COG0028	Belongs to the TPP enzyme family
LUZ17_21010	COG4191	Histidine kinase
LUZ17_21035	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LUZ17_21050	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LUZ17_21055	COG3177	Filamentation induced by cAMP protein fic
LUZ17_21070	COG0596	Alpha beta hydrolase
LUZ17_21075	COG0727	PFAM Uncharacterised protein family (UPF0153)
LUZ17_21080	COG0318	PFAM AMP-dependent synthetase and ligase
LUZ17_21085	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LUZ17_21135	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LUZ17_21145	COG0129	dihydroxy-acid dehydratase activity
LUZ17_21170	COG3039	Transposase
LUZ17_21180	COG0408	coproporphyrinogen oxidase activity
LUZ17_21270	COG2353	YceI-like domain
LUZ17_21300	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LUZ17_21315	COG3386	PFAM SMP-30 Gluconolaconase
LUZ17_21345	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LUZ17_21365	COG0459	protein refolding
LUZ17_21390	COG1252	NADH dehydrogenase
LUZ17_21400	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LUZ17_21405	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LUZ17_21410	COG2201	protein-glutamate methylesterase activity
LUZ17_21415	COG2177	Part of the ABC transporter FtsEX involved in
LUZ17_21420	COG2884	Cell division ATP-binding protein ftsE
LUZ17_21430	COG3118	belongs to the thioredoxin family
LUZ17_21435	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LUZ17_21450	COG0729	surface antigen
LUZ17_21455	COG2911	Protein conserved in bacteria
LUZ17_21505	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LUZ17_21560	COG1733	regulation of RNA biosynthetic process
LUZ17_21565	COG0702	epimerase
LUZ17_21595	COG0583	DNA-binding transcription factor activity
LUZ17_21600	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LUZ17_21620	COG0745	RESPONSE REGULATOR receiver
LUZ17_21650	COG1902	pentaerythritol trinitrate reductase activity
LUZ17_21655	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LUZ17_21665	COG2814	Major facilitator Superfamily
LUZ17_21670	COG0583	DNA-binding transcription factor activity
LUZ17_21685	COG0084	hydrolase, TatD family'
LUZ17_21735	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LUZ17_21810	COG4770	biotin carboxylase activity
LUZ17_21815	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LUZ17_21820	COG1960	acyl-CoA dehydrogenase activity
LUZ17_21875	COG0523	cobalamin synthesis protein
LUZ17_21895	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LUZ17_21910	COG4771	TonB-dependent receptor
LUZ17_21915	COG0457	Tetratricopeptide repeat
LUZ17_21930	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LUZ17_21945	COG0519	Catalyzes the synthesis of GMP from XMP
LUZ17_21945	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LUZ17_21955	COG0805	protein transport
LUZ17_21965	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LUZ17_21975	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LUZ17_22025	COG3661	Belongs to the glycosyl hydrolase 67 family
LUZ17_22035	COG4948	Mandelate Racemase Muconate Lactonizing
LUZ17_22045	COG1472	Belongs to the glycosyl hydrolase 3 family
LUZ17_22050	COG0246	Mannitol dehydrogenase
LUZ17_22075	COG3693	PFAM glycoside hydrolase, family 10
LUZ17_22100	COG2211	Major facilitator Superfamily
LUZ17_22195	COG1846	Transcriptional regulator
LUZ17_22200	COG1764	response to oxidative stress
LUZ17_22285	COG3549	Plasmid maintenance system killer
LUZ17_22295	COG1074	ATP-dependent DNA helicase activity
LUZ17_22300	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LUZ17_22315	COG1196	nuclear chromosome segregation
LUZ17_22350	COG2032	superoxide dismutase activity
LUZ17_22355	COG2032	superoxide dismutase activity
LUZ17_22360	COG2204	response regulator
LUZ17_22365	COG3852	Histidine kinase
LUZ17_22370	COG0004	ammonium transporteR
LUZ17_22375	COG0347	Belongs to the P(II) protein family
LUZ17_22380	COG0174	glutamine synthetase
LUZ17_22385	COG1968	undecaprenyl-diphosphatase activity
LUZ17_22425	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LUZ17_22435	COG2062	phosphohistidine phosphatase, SixA
LUZ17_22440	COG0489	protein tyrosine kinase activity
LUZ17_22460	COG1396	sequence-specific DNA binding
LUZ17_22465	COG3550	peptidyl-serine autophosphorylation
LUZ17_22470	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
LUZ17_22475	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LUZ17_22490	COG0517	IMP dehydrogenase activity
LUZ17_22490	COG1125	glycine betaine transport
LUZ17_22505	COG1119	ATPase activity
LUZ17_22515	COG1752	Esterase of the alpha-beta hydrolase superfamily
LUZ17_22530	COG3039	Transposase
LUZ17_22555	COG0656	L-ascorbic acid biosynthetic process
LUZ17_22560	COG2130	NADP-dependent
LUZ17_22565	COG0667	Aldo Keto reductase
LUZ17_22575	COG1187	pseudouridine synthase activity
LUZ17_22590	COG1643	Atp-dependent helicase
LUZ17_22595	COG4807	Protein conserved in bacteria
LUZ17_22600	COG4948	Mandelate Racemase Muconate Lactonizing
LUZ17_22605	COG0179	Fumarylacetoacetate (FAA) hydrolase
LUZ17_22610	COG1028	Short-chain dehydrogenase reductase Sdr
LUZ17_22670	COG3162	membrane
LUZ17_22675	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LUZ17_22690	COG0708	Exodeoxyribonuclease III
LUZ17_22705	COG2091	lysine biosynthetic process via aminoadipic acid
LUZ17_22715	COG3540	Alkaline phosphatase
LUZ17_22765	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LUZ17_22770	COG0583	DNA-binding transcription factor activity
LUZ17_22775	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LUZ17_22790	COG0210	DNA helicase
LUZ17_22805	COG0531	amino acid
LUZ17_22815	COG1322	Protein conserved in bacteria
LUZ17_22825	COG0386	Belongs to the glutathione peroxidase family
LUZ17_22875	COG0793	Belongs to the peptidase S41A family
LUZ17_22880	COG4942	peptidase
LUZ17_22890	COG2234	aminopeptidase activity
LUZ17_22935	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LUZ17_22940	COG0302	gtp cyclohydrolase
LUZ17_22965	COG0477	Major facilitator Superfamily
LUZ17_23060	COG1929	Belongs to the glycerate kinase type-1 family
LUZ17_23065	COG2271	Major facilitator Superfamily
LUZ17_23080	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LUZ17_23085	COG0861	Integral membrane protein TerC family
LUZ17_23095	COG0584	glycerophosphoryl diester phosphodiesterase
LUZ17_23105	COG0671	phosphoesterase, PA-phosphatase related
LUZ17_23115	COG0726	polysaccharide deacetylase