locus-tag	class	description
DZA53_00030	COG0187	DNA topoisomerase II activity
DZA53_00040	COG0501	Belongs to the peptidase M48B family
DZA53_00070	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DZA53_00080	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DZA53_00100	COG4772	TonB-dependent receptor
DZA53_00115	COG3039	Transposase
DZA53_00150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DZA53_00260	COG2826	transposase and inactivated derivatives, IS30 family
DZA53_00285	COG3039	Transposase
DZA53_00295	COG1090	epimerase
DZA53_00305	COG0642	Histidine kinase
DZA53_00315	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DZA53_00430	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DZA53_00510	COG3264	Mechanosensitive ion channel
DZA53_00510	COG1511	domain protein
DZA53_00535	COG3039	Transposase
DZA53_00555	COG3039	Transposase
DZA53_00560	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DZA53_00570	COG2354	Protein conserved in bacteria
DZA53_00580	COG3706	GGDEF domain
DZA53_00580	COG0745	RESPONSE REGULATOR receiver
DZA53_00595	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DZA53_00620	COG0702	epimerase
DZA53_00630	COG1858	cytochrome C peroxidase
DZA53_00720	COG0513	Belongs to the DEAD box helicase family
DZA53_00730	COG3039	Transposase
DZA53_00780	COG1136	(ABC) transporter
DZA53_00795	COG3039	Transposase
DZA53_00805	COG3039	Transposase
DZA53_00820	COG1136	(ABC) transporter
DZA53_00865	COG1272	protein, Hemolysin III
DZA53_00870	COG1205	dead DEAH box helicase
DZA53_00870	COG1111	helicase
DZA53_00935	COG0070	glutamate synthase
DZA53_00935	COG0069	glutamate synthase activity
DZA53_00935	COG0067	glutamate synthase
DZA53_00940	COG0493	'glutamate synthase
DZA53_00995	COG1609	Transcriptional regulator
DZA53_01030	COG0366	Alpha amylase catalytic
DZA53_01035	COG0366	Alpha amylase catalytic
DZA53_01105	COG0606	chelatase, subunit chli
DZA53_01165	COG1166	arginine decarboxylase activity
DZA53_01175	COG3501	Rhs element vgr protein
DZA53_01255	COG1028	Short-chain dehydrogenase reductase Sdr
DZA53_01280	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
DZA53_01295	COG0210	DNA helicase
DZA53_01315	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
DZA53_01355	COG2937	Belongs to the GPAT DAPAT family
DZA53_01425	COG1752	Esterase of the alpha-beta hydrolase superfamily
DZA53_01435	COG1119	ATPase activity
DZA53_01450	COG0517	IMP dehydrogenase activity
DZA53_01450	COG1125	glycine betaine transport
DZA53_01465	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DZA53_01470	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
DZA53_01475	COG3550	peptidyl-serine autophosphorylation
DZA53_01480	COG1396	sequence-specific DNA binding
DZA53_01500	COG0489	protein tyrosine kinase activity
DZA53_01505	COG2062	phosphohistidine phosphatase, SixA
DZA53_01515	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DZA53_01565	COG0174	glutamine synthetase
DZA53_01570	COG0347	Belongs to the P(II) protein family
DZA53_01575	COG0004	ammonium transporteR
DZA53_01580	COG3852	Histidine kinase
DZA53_01585	COG2204	response regulator
DZA53_01590	COG2032	superoxide dismutase activity
DZA53_01595	COG2032	superoxide dismutase activity
DZA53_01630	COG1196	nuclear chromosome segregation
DZA53_01635	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
DZA53_01640	COG1074	ATP-dependent DNA helicase activity
DZA53_01650	COG3549	Plasmid maintenance system killer
DZA53_01750	COG1764	response to oxidative stress
DZA53_01755	COG1846	Transcriptional regulator
DZA53_01805	COG4943	cyclic-guanylate-specific phosphodiesterase activity
DZA53_01850	COG2211	Major facilitator Superfamily
DZA53_01875	COG3693	PFAM glycoside hydrolase, family 10
DZA53_01900	COG0246	Mannitol dehydrogenase
DZA53_01905	COG1472	Belongs to the glycosyl hydrolase 3 family
DZA53_01915	COG4948	Mandelate Racemase Muconate Lactonizing
DZA53_01925	COG3661	Belongs to the glycosyl hydrolase 67 family
DZA53_01945	COG0037	tRNA processing
DZA53_01950	COG2974	May be involved in recombination
DZA53_01980	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DZA53_01990	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DZA53_02000	COG0805	protein transport
DZA53_02010	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DZA53_02010	COG0519	Catalyzes the synthesis of GMP from XMP
DZA53_02035	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DZA53_02040	COG0752	glycyl-tRNA synthetase alpha subunit
DZA53_02050	COG0457	Tetratricopeptide repeat
DZA53_02055	COG4771	TonB-dependent receptor
DZA53_02070	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DZA53_02090	COG0523	cobalamin synthesis protein
DZA53_02145	COG1960	acyl-CoA dehydrogenase activity
DZA53_02150	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DZA53_02220	COG2072	flavoprotein involved in K transport
DZA53_02240	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DZA53_02295	COG0084	hydrolase, TatD family'
DZA53_02315	COG0583	DNA-binding transcription factor activity
DZA53_02320	COG2814	Major facilitator Superfamily
DZA53_02330	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DZA53_02335	COG1902	pentaerythritol trinitrate reductase activity
DZA53_02365	COG0745	RESPONSE REGULATOR receiver
DZA53_02385	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DZA53_02390	COG0583	DNA-binding transcription factor activity
DZA53_02425	COG0702	epimerase
DZA53_02430	COG1733	regulation of RNA biosynthetic process
DZA53_02490	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DZA53_02505	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DZA53_02540	COG2911	Protein conserved in bacteria
DZA53_02545	COG0729	surface antigen
DZA53_02560	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DZA53_02565	COG3118	belongs to the thioredoxin family
DZA53_02575	COG2884	Cell division ATP-binding protein ftsE
DZA53_02580	COG2177	Part of the ABC transporter FtsEX involved in
DZA53_02585	COG3437	response regulator, receiver
DZA53_02595	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DZA53_02605	COG1252	NADH dehydrogenase
DZA53_02625	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DZA53_02640	COG4771	TonB-dependent receptor
DZA53_02655	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DZA53_02695	COG3386	PFAM SMP-30 Gluconolaconase
DZA53_02710	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DZA53_02745	COG0778	Nitroreductase
DZA53_02750	COG2353	YceI-like domain
DZA53_02855	COG3039	Transposase
DZA53_02890	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DZA53_02930	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DZA53_02935	COG0318	PFAM AMP-dependent synthetase and ligase
DZA53_02945	COG0596	Alpha beta hydrolase
DZA53_02960	COG3177	Filamentation induced by cAMP protein fic
DZA53_02965	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DZA53_02980	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DZA53_03005	COG4191	Histidine kinase
DZA53_03010	COG0028	Belongs to the TPP enzyme family
DZA53_03030	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DZA53_03070	COG5383	Protein conserved in bacteria
DZA53_03085	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DZA53_03090	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DZA53_03095	COG1473	amidohydrolase
DZA53_03275	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DZA53_03290	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
DZA53_03355	COG3039	Transposase
DZA53_03380	COG1271	oxidase subunit
DZA53_03445	COG2972	Histidine kinase
DZA53_03470	COG0531	amino acid
DZA53_03490	COG3590	peptidase
DZA53_03505	COG0667	Aldo Keto reductase
DZA53_03520	COG3384	dioxygenase
DZA53_03530	COG1573	uracil-dna glycosylase
DZA53_03540	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
DZA53_03550	COG0025	NhaP-type Na H and K H
DZA53_03555	COG1131	(ABC) transporter
DZA53_03560	COG0842	Transport permease protein
DZA53_03575	COG1404	Belongs to the peptidase S8 family
DZA53_03590	COG0745	RESPONSE REGULATOR receiver
DZA53_03635	COG1522	sequence-specific DNA binding
DZA53_03640	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DZA53_03665	COG2202	Pas domain
DZA53_03665	COG2205	protein histidine kinase activity
DZA53_03700	COG2813	Specifically methylates the guanine in position
DZA53_03705	COG1187	pseudouridine synthase activity
DZA53_03710	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DZA53_03750	COG0697	spore germination
DZA53_03760	COG2011	ABC-type metal ion transport system permease component
DZA53_03790	COG0508	dehydrogenase complex catalyzes the overall conversion of
DZA53_03800	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DZA53_03820	COG0356	it plays a direct role in the translocation of protons across the membrane
DZA53_03855	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DZA53_03915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DZA53_03920	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DZA53_03970	COG0339	signal peptide processing
DZA53_04010	COG1956	GAF domain-containing protein
DZA53_04025	COG0720	synthase
DZA53_04035	COG0513	Belongs to the DEAD box helicase family
DZA53_04050	COG0625	glutathione transferase activity
DZA53_04080	COG0626	cystathionine gamma-synthase activity
DZA53_04100	COG1216	Glycosyl transferase, family 2
DZA53_04100	COG0438	transferase activity, transferring glycosyl groups
DZA53_04135	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
DZA53_04140	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DZA53_04155	COG0277	FAD linked oxidase domain protein
DZA53_04160	COG0546	phosphoglycolate phosphatase activity
DZA53_04160	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DZA53_04175	COG2086	electron transfer activity
DZA53_04200	COG0662	Cupin 2, conserved barrel domain protein
DZA53_04200	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
DZA53_04205	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DZA53_04245	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DZA53_04245	COG3218	ABC-type transport auxiliary lipoprotein component
DZA53_04250	COG1127	ABC transporter
DZA53_04255	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DZA53_04280	COG1183	phosphatidylcholine synthase activity
DZA53_04315	COG3039	Transposase
DZA53_04355	COG3039	Transposase
DZA53_04395	COG0525	valine-tRNA ligase activity
DZA53_04420	COG0795	lipopolysaccharide-transporting ATPase activity
DZA53_04435	COG4974	Belongs to the 'phage' integrase family
DZA53_04440	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DZA53_04445	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DZA53_04445	COG0047	phosphoribosylformylglycinamidine synthase activity
DZA53_04455	COG5295	Hep Hag repeat protein
DZA53_04465	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DZA53_04475	COG1459	type II secretion system
DZA53_04480	COG2165	general secretion pathway protein
DZA53_04485	COG4970	Tfp pilus assembly protein FimT
DZA53_04490	COG2165	general secretion pathway protein
DZA53_04495	COG4795	General secretion pathway protein
DZA53_04500	COG3156	type II secretion system protein K
DZA53_04505	COG3166	PFAM Fimbrial assembly family protein
DZA53_04520	COG1450	Type ii and iii secretion system protein
DZA53_04535	COG2188	Transcriptional regulator
DZA53_04590	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DZA53_04595	COG1518	maintenance of DNA repeat elements
DZA53_04640	COG1399	metal-binding, possibly nucleic acid-binding protein
DZA53_04665	COG1028	Short-chain dehydrogenase reductase Sdr
DZA53_04680	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DZA53_04685	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DZA53_04710	COG3829	transcription factor binding
DZA53_04820	COG2826	transposase and inactivated derivatives, IS30 family
DZA53_04830	COG0678	peroxiredoxin activity
DZA53_04850	COG0330	HflC and HflK could
DZA53_04855	COG0330	HflC and HflK could
DZA53_04865	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DZA53_04870	COG0308	aminopeptidase N
DZA53_04920	COG1560	Kdo2-lipid A biosynthetic process
DZA53_04925	COG1519	Transferase
DZA53_04930	COG1538	Outer membrane efflux protein
DZA53_04935	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DZA53_04975	COG2226	methyltransferase
DZA53_05020	COG3710	Transcriptional regulator
DZA53_05045	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DZA53_05065	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DZA53_05095	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DZA53_05105	COG3781	membrane
DZA53_05260	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
DZA53_05285	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DZA53_05290	COG0039	L-malate dehydrogenase activity
DZA53_05295	COG0625	glutathione transferase activity
DZA53_05315	COG3039	Transposase
DZA53_05345	COG0584	glycerophosphoryl diester phosphodiesterase
DZA53_05375	COG1902	pentaerythritol trinitrate reductase activity
DZA53_05375	COG0446	pyridine nucleotide-disulphide oxidoreductase
DZA53_05410	COG0156	8-amino-7-oxononanoate synthase activity
DZA53_05415	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DZA53_05420	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DZA53_05425	COG4208	sulfate ABC transporter
DZA53_05430	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DZA53_05475	COG0406	alpha-ribazole phosphatase activity
DZA53_05485	COG0285	dihydrofolate synthase activity
DZA53_05505	COG2833	Protein of unknown function (DUF455)
DZA53_05530	COG0671	phosphoesterase, PA-phosphatase related
DZA53_05535	COG0438	transferase activity, transferring glycosyl groups
DZA53_05545	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DZA53_05560	COG4783	chaperone-mediated protein folding
DZA53_05585	COG0473	3-isopropylmalate dehydrogenase activity
DZA53_05640	COG0544	peptidyl-prolyl cis-trans isomerase activity
DZA53_05645	COG0740	serine-type endopeptidase activity
DZA53_05680	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DZA53_05705	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DZA53_05715	COG0631	protein serine/threonine phosphatase activity
DZA53_05825	COG0582	viral genome integration into host DNA
DZA53_05835	COG0859	PFAM glycosyl transferase family 9
DZA53_05845	COG1234	tRNA 3'-trailer cleavage
DZA53_05850	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DZA53_05865	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DZA53_05870	COG0314	molybdopterin synthase activity
DZA53_05900	COG0537	adenosine 5'-monophosphoramidase activity
DZA53_05920	COG0714	Associated with various cellular activities
DZA53_05940	COG0242	peptide deformylase activity
DZA53_05990	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DZA53_05995	COG0726	polysaccharide deacetylase
DZA53_06020	COG1162	GTPase activity
DZA53_06045	COG2211	Major facilitator Superfamily
DZA53_06055	COG1609	Transcriptional regulator
DZA53_06060	COG1028	Short-chain dehydrogenase reductase Sdr
DZA53_06065	COG2851	Citrate transporter
DZA53_06085	COG0642	Histidine kinase
DZA53_06090	COG1840	ABC-type Fe3 transport system, periplasmic component
DZA53_06095	COG2197	response regulator
DZA53_06120	COG0583	DNA-binding transcription factor activity
DZA53_06135	COG4191	Histidine kinase
DZA53_06155	COG0281	malic enzyme
DZA53_06155	COG0280	phosphate acetyltransferase
DZA53_06190	COG0352	thiamine-phosphate diphosphorylase activity
DZA53_06195	COG1773	rubredoxin
DZA53_06200	COG2912	Transglutaminase-like superfamily
DZA53_06210	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DZA53_06245	COG0006	proline dipeptidase activity
DZA53_06275	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DZA53_06295	COG1561	YicC-like family, N-terminal region
DZA53_06320	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DZA53_06330	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DZA53_06340	COG0254	rRNA binding
DZA53_06355	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DZA53_06395	COG0714	Associated with various cellular activities
DZA53_06415	COG2304	oxidoreductase activity
DZA53_06435	COG1301	dicarboxylic acid transport
DZA53_06440	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DZA53_06450	COG0739	heme binding
DZA53_06455	COG1376	ErfK ybiS ycfS ynhG family protein
DZA53_06480	COG1022	Amp-dependent synthetase and ligase
DZA53_06490	COG1028	Short-chain dehydrogenase reductase Sdr
DZA53_06500	COG0745	RESPONSE REGULATOR receiver
DZA53_06505	COG0642	Histidine kinase
DZA53_06525	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
DZA53_06530	COG4149	molybdate abc transporter
DZA53_06535	COG0725	ABC transporter, periplasmic molybdate-binding protein
DZA53_06540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DZA53_06540	COG3453	Protein conserved in bacteria
DZA53_06585	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DZA53_06605	COG2205	protein histidine kinase activity
DZA53_06610	COG3039	Transposase
DZA53_06615	COG0745	RESPONSE REGULATOR receiver
DZA53_06630	COG3039	Transposase
DZA53_06665	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DZA53_06670	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DZA53_06725	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DZA53_06755	COG2201	protein-glutamate methylesterase activity
DZA53_06840	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DZA53_06850	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DZA53_06870	COG1842	Phage shock protein A
DZA53_06895	COG0754	glutathionylspermidine amidase activity
DZA53_06910	COG0789	Transcriptional regulator
DZA53_06965	COG0531	amino acid
DZA53_06970	COG2197	response regulator
DZA53_06985	COG1113	amino acid transport
DZA53_07005	COG1271	oxidase subunit
DZA53_07010	COG1294	oxidase, subunit
DZA53_07020	COG2239	Acts as a magnesium transporter
DZA53_07030	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DZA53_07035	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DZA53_07055	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DZA53_07070	COG1137	ATPase activity
DZA53_07075	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
DZA53_07085	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DZA53_07095	COG0271	Belongs to the BolA IbaG family
DZA53_07120	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DZA53_07145	COG0628	permease
DZA53_07155	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DZA53_07160	COG3178	'Phosphotransferase
DZA53_07175	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DZA53_07180	COG1555	photosystem II stabilization
DZA53_07235	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DZA53_07245	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DZA53_07295	COG0534	Mate efflux family protein
DZA53_07340	COG0542	response to heat
DZA53_07380	COG4206	TonB-dependent receptor
DZA53_07440	COG0019	diaminopimelate decarboxylase activity
DZA53_07455	COG4264	IucA IucC family
DZA53_07465	COG4772	TonB-dependent receptor
DZA53_07480	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DZA53_07480	COG4651	solute:proton antiporter activity
DZA53_07510	COG0488	(ABC) transporter
DZA53_07535	COG2755	lipolytic protein G-D-S-L family
DZA53_07535	COG0657	acetylesterase activity
DZA53_07555	COG2207	Transcriptional regulator
DZA53_07560	COG0326	Molecular chaperone. Has ATPase activity
DZA53_07595	COG0174	glutamine synthetase
DZA53_07600	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
DZA53_07610	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DZA53_07670	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DZA53_07675	COG0719	Fe-S assembly protein
DZA53_07680	COG0396	ATPase activity
DZA53_07685	COG0719	Fe-S assembly protein
DZA53_07690	COG1959	2 iron, 2 sulfur cluster binding
DZA53_07710	COG0693	protein deglycase activity
DZA53_07755	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DZA53_07790	COG0519	Catalyzes the synthesis of GMP from XMP
DZA53_07820	COG1764	response to oxidative stress
DZA53_07830	COG0384	phenazine biosynthesis protein PhzF
DZA53_07840	COG0527	aspartate kinase activity
DZA53_07870	COG0142	geranyltranstransferase activity
DZA53_07875	COG0629	single-stranded DNA binding
DZA53_07885	COG4251	negative regulation of phosphorylation
DZA53_07885	COG5001	Diguanylate cyclase
DZA53_07885	COG2203	Gaf domain
DZA53_07885	COG3706	GGDEF domain
DZA53_07930	COG2879	small protein
DZA53_07935	COG1966	Carbon starvation protein
DZA53_07940	COG1741	Belongs to the pirin family
DZA53_07950	COG3501	Rhs element vgr protein
DZA53_07995	COG3501	Rhs element vgr protein
DZA53_08000	COG3179	chitinase
DZA53_08005	COG3501	Rhs element vgr protein
DZA53_08070	COG3501	Rhs element vgr protein
DZA53_08135	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
DZA53_08170	COG0732	type I restriction modification DNA specificity domain
DZA53_08210	COG0328	RNA-DNA hybrid ribonuclease activity
DZA53_08210	COG0406	alpha-ribazole phosphatase activity
DZA53_08260	COG0587	DNA-directed DNA polymerase activity
DZA53_08280	COG1297	OPT oligopeptide transporter protein
DZA53_08305	COG1506	peptidase
DZA53_08305	COG0823	Involved in the tonB-independent uptake of proteins
DZA53_08325	COG2207	Transcriptional regulator
DZA53_08325	COG1917	Cupin 2, conserved barrel domain protein
DZA53_08355	COG0753	catalase activity
DZA53_08390	COG0126	phosphoglycerate kinase activity
DZA53_08400	COG0469	pyruvate kinase activity
DZA53_08410	COG3588	fructose-bisphosphate aldolase
DZA53_08415	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
DZA53_08465	COG2205	protein histidine kinase activity
DZA53_08465	COG2198	Histidine kinase
DZA53_08465	COG0784	Response regulator, receiver
DZA53_08500	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DZA53_08510	COG0529	Catalyzes the synthesis of activated sulfate
DZA53_08510	COG2895	sulfate adenylyltransferase (ATP) activity
DZA53_08515	COG3039	Transposase
DZA53_08530	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DZA53_08535	COG0308	aminopeptidase N
DZA53_08565	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DZA53_08590	COG1970	mechanosensitive ion channel activity
DZA53_08620	COG3273	potassium ion transport
DZA53_08620	COG0471	metal ion transport
DZA53_08730	COG3039	Transposase
DZA53_08835	COG3118	belongs to the thioredoxin family
DZA53_08845	COG0495	leucyl-tRNA aminoacylation
DZA53_08865	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DZA53_08920	COG2968	Membrane
DZA53_08930	COG1530	ribonuclease E activity
DZA53_08935	COG3164	Protein of unknown function
DZA53_08945	COG0312	modulator of DNA gyrase
DZA53_08950	COG3028	Belongs to the UPF0307 family
DZA53_08955	COG0312	modulator of DNA gyrase
DZA53_08980	COG0142	geranyltranstransferase activity
DZA53_08990	COG0037	tRNA processing
DZA53_08995	COG1785	Belongs to the alkaline phosphatase family
DZA53_09000	COG1301	dicarboxylic acid transport
DZA53_09015	COG0791	NLP P60 protein
DZA53_09020	COG0791	NLP P60 protein
DZA53_09025	COG1047	Peptidyl-prolyl cis-trans
DZA53_09030	COG2311	Membrane
DZA53_09035	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DZA53_09080	COG0489	protein tyrosine kinase activity
DZA53_09105	COG0412	Dienelactone hydrolase
DZA53_09115	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DZA53_09170	COG2890	protein-(glutamine-N5) methyltransferase activity
DZA53_09180	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DZA53_09185	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DZA53_09220	COG0133	tryptophan synthase activity
DZA53_09230	COG0159	tryptophan synthase activity
DZA53_09295	COG1028	Short-chain dehydrogenase reductase Sdr
DZA53_09315	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DZA53_09335	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
DZA53_09340	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DZA53_09345	COG1034	ATP synthesis coupled electron transport
DZA53_09350	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DZA53_09365	COG0713	ATP synthesis coupled electron transport
DZA53_09380	COG1007	ATP synthesis coupled electron transport
DZA53_09395	COG0195	Participates in both transcription termination and antitermination
DZA53_09400	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DZA53_09415	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DZA53_09450	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DZA53_09455	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DZA53_09465	COG2095	MarC family integral membrane protein
DZA53_09480	COG1611	Belongs to the LOG family
DZA53_09520	COG4969	Belongs to the N-Me-Phe pilin family
DZA53_09525	COG0556	nucleotide-excision repair
DZA53_09565	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DZA53_09570	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DZA53_09575	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DZA53_09580	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DZA53_09590	COG0776	regulation of translation
DZA53_09635	COG0438	transferase activity, transferring glycosyl groups
DZA53_09640	COG0438	transferase activity, transferring glycosyl groups
DZA53_09690	COG3040	lipid binding
DZA53_09785	COG4191	Histidine kinase
DZA53_09785	COG0784	Response regulator, receiver
DZA53_09810	COG0552	protein localization to endoplasmic reticulum
DZA53_09820	COG3938	Belongs to the proline racemase family
DZA53_09825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DZA53_09840	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DZA53_09850	COG0006	proline dipeptidase activity
DZA53_09865	COG0531	amino acid
DZA53_09915	COG4206	TonB-dependent receptor
DZA53_10000	COG0746	molybdenum cofactor guanylyltransferase activity
DZA53_10025	COG1648	precorrin-2 dehydrogenase activity
DZA53_10025	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DZA53_10070	COG3039	Transposase
DZA53_10075	COG3039	Transposase
DZA53_10120	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
DZA53_10160	COG1530	ribonuclease E activity
DZA53_10170	COG3064	Membrane
DZA53_10175	COG0428	transporter
DZA53_10180	COG0428	transporter
DZA53_10190	COG2154	pterin-4-alpha-carbinolamine dehydratase
DZA53_10195	COG0316	Belongs to the HesB IscA family
DZA53_10195	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
DZA53_10220	COG3501	Rhs element vgr protein
DZA53_10355	COG0824	Thioesterase
DZA53_10365	COG0848	biopolymer transport protein
DZA53_10375	COG0823	Involved in the tonB-independent uptake of proteins
DZA53_10380	COG2885	chlorophyll binding
DZA53_10390	COG0602	queuosine metabolic process
DZA53_10440	COG0514	ATP-dependent DNA helicase (RecQ)
DZA53_10450	COG0783	Belongs to the Dps family
DZA53_10455	COG1643	Atp-dependent helicase
DZA53_10480	COG0535	radical SAM domain protein
DZA53_10485	COG0535	radical SAM domain protein
DZA53_10490	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
DZA53_10505	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DZA53_10520	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DZA53_10530	COG1199	ATP-dependent helicase activity
DZA53_10540	COG1397	ADP-ribosylglycohydrolase
DZA53_10550	COG0189	ligase activity
DZA53_10565	COG0835	chemotaxis
DZA53_10570	COG0840	transmembrane signaling receptor activity
DZA53_10630	COG1446	asparaginase
DZA53_10635	COG3142	Participates in the control of copper homeostasis
DZA53_10680	COG3537	Alpha-1,2-mannosidase
DZA53_10750	COG1472	Belongs to the glycosyl hydrolase 3 family
DZA53_10770	COG1388	LysM domain
DZA53_10770	COG3858	chitin binding
DZA53_10785	COG0837	glucose binding
DZA53_10790	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DZA53_10800	COG0494	nUDIX hydrolase
DZA53_10810	COG3956	TIGRFAM MazG family protein
DZA53_10825	COG0330	HflC and HflK could
DZA53_10875	COG1960	acyl-CoA dehydrogenase activity
DZA53_10885	COG1309	transcriptional regulator
DZA53_10890	COG4771	TonB-dependent receptor
DZA53_10900	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DZA53_10910	COG0463	Glycosyl transferase, family 2
DZA53_10935	COG1272	protein, Hemolysin III
DZA53_10940	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DZA53_10945	COG0739	heme binding
DZA53_10950	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DZA53_10955	COG0626	cystathionine gamma-synthase activity
DZA53_10965	COG1760	l-serine dehydratase
DZA53_10980	COG2353	YceI-like domain
DZA53_10990	COG2353	YceI-like domain
DZA53_11060	COG1960	acyl-CoA dehydrogenase activity
DZA53_11065	COG1024	Enoyl-CoA hydratase
DZA53_11085	COG1250	3-hydroxyacyl-CoA dehydrogenase
DZA53_11085	COG1024	Enoyl-CoA hydratase
DZA53_11100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DZA53_11165	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
DZA53_11170	COG3046	protein related to deoxyribodipyrimidine photolyase
DZA53_11185	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DZA53_11190	COG1278	Cold shock
DZA53_11210	COG1201	RNA secondary structure unwinding
DZA53_11215	COG1793	dna ligase
DZA53_11225	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DZA53_11225	COG1793	dna ligase
DZA53_11240	COG0745	RESPONSE REGULATOR receiver
DZA53_11240	COG3706	GGDEF domain
DZA53_11255	COG0183	Belongs to the thiolase family
DZA53_11280	COG1451	nucleotide metabolic process
DZA53_11295	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DZA53_11300	COG3039	Transposase
DZA53_11335	COG1047	Peptidyl-prolyl cis-trans
DZA53_11350	COG2824	Alkylphosphonate utilization operon protein PhnA
DZA53_11365	COG1902	pentaerythritol trinitrate reductase activity
DZA53_11370	COG2814	Major facilitator Superfamily
DZA53_11415	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DZA53_11415	COG0392	lysyltransferase activity
DZA53_11425	COG0251	oxidation-reduction process
DZA53_11430	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DZA53_11445	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DZA53_11470	COG1595	DNA-templated transcription, initiation
DZA53_11490	COG2878	Part of a membrane complex involved in electron transport
DZA53_11520	COG0833	amino acid
DZA53_11525	COG2040	homocysteine
DZA53_11545	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DZA53_11585	COG2895	sulfate adenylyltransferase (ATP) activity
DZA53_11585	COG0529	Catalyzes the synthesis of activated sulfate
DZA53_11660	COG1131	(ABC) transporter
DZA53_11665	COG4771	TonB-dependent receptor
DZA53_11720	COG0750	zinc metalloprotease
DZA53_11730	COG0575	Belongs to the CDS family
DZA53_11795	COG0024	Methionine aminopeptidase
DZA53_11815	COG1393	Belongs to the ArsC family
DZA53_11825	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DZA53_11830	COG0367	asparagine synthase
DZA53_11845	COG4774	siderophore transport
DZA53_11880	COG2207	Transcriptional regulator
DZA53_11895	COG1566	PFAM secretion protein HlyD family protein
DZA53_11900	COG2814	Major facilitator Superfamily
DZA53_11955	COG1960	acyl-CoA dehydrogenase activity
DZA53_11970	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DZA53_11980	COG2914	Belongs to the UPF0125 (RnfH) family
DZA53_11990	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DZA53_12000	COG0497	DNA recombination
DZA53_12030	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
DZA53_12035	COG0287	Prephenate dehydrogenase
DZA53_12035	COG1605	Chorismate mutase
DZA53_12055	COG0583	DNA-binding transcription factor activity
DZA53_12070	COG1132	(ABC) transporter
DZA53_12105	COG2850	peptidyl-arginine hydroxylation
DZA53_12150	COG3039	Transposase
DZA53_12190	COG1131	(ABC) transporter
DZA53_12195	COG1725	Transcriptional regulator
DZA53_12205	COG0386	Belongs to the glutathione peroxidase family
DZA53_12245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DZA53_12255	COG0646	methionine synthase
DZA53_12255	COG1410	methionine synthase
DZA53_12260	COG1410	methionine synthase
DZA53_12260	COG0646	methionine synthase
DZA53_12270	COG1960	acyl-CoA dehydrogenase activity
DZA53_12310	COG0557	exoribonuclease II activity
DZA53_12325	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DZA53_12340	COG3039	Transposase
DZA53_12380	COG3328	transposase activity
DZA53_12390	COG1278	Cold shock
DZA53_12475	COG3039	Transposase
DZA53_12485	COG0583	DNA-binding transcription factor activity
DZA53_12550	COG3209	COG3209 Rhs family protein
DZA53_12615	COG0643	Histidine kinase
DZA53_12615	COG2198	Histidine kinase
DZA53_12635	COG0455	bacterial-type flagellum organization
DZA53_12645	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DZA53_12660	COG5001	Diguanylate cyclase
DZA53_12660	COG3300	MHYT domain
DZA53_12665	COG5001	Diguanylate cyclase
DZA53_12665	COG3300	MHYT domain
DZA53_12670	COG1684	flagellar biosynthetic protein fliR
DZA53_12675	COG1987	bacterial-type flagellum assembly
DZA53_12690	COG3190	flagellar
DZA53_12740	COG1677	Flagellar hook-basal body complex protein FliE
DZA53_12790	COG1028	Short-chain dehydrogenase reductase Sdr
DZA53_12800	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DZA53_12815	COG2204	response regulator
DZA53_12820	COG2201	protein-glutamate methylesterase activity
DZA53_12850	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
DZA53_12855	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DZA53_12885	COG4786	Flagellar basal body rod
DZA53_12895	COG4787	bacterial-type flagellum-dependent cell motility
DZA53_12900	COG1749	Flagellar hook protein flgE
DZA53_12905	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DZA53_12910	COG1558	bacterial-type flagellum-dependent cell motility
DZA53_12920	COG0784	Response regulator, receiver
DZA53_12920	COG0835	chemotaxis
DZA53_12940	COG5002	protein histidine kinase activity
DZA53_12950	COG4585	Histidine kinase
DZA53_12955	COG5001	Diguanylate cyclase
DZA53_12980	COG0482	sulfurtransferase activity
DZA53_12990	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DZA53_12995	COG0542	response to heat
DZA53_13000	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DZA53_13020	COG0492	ferredoxin-NADP+ reductase activity
DZA53_13025	COG1674	ftsk spoiiie
DZA53_13050	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DZA53_13070	COG0038	chloride channel
DZA53_13075	COG0183	Belongs to the thiolase family
DZA53_13080	COG1024	Enoyl-CoA hydratase
DZA53_13080	COG1250	3-hydroxyacyl-CoA dehydrogenase
DZA53_13090	COG0105	UTP biosynthetic process
DZA53_13105	COG1426	Protein conserved in bacteria
DZA53_13115	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DZA53_13125	COG0303	'Molybdopterin
DZA53_13205	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DZA53_13215	COG3039	Transposase
DZA53_13245	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
DZA53_13255	COG0235	Class ii aldolase
DZA53_13260	COG0531	amino acid
DZA53_13265	COG0531	amino acid
DZA53_13275	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DZA53_13280	COG0277	FAD linked oxidase domain protein
DZA53_13345	COG0436	Aminotransferase
DZA53_13370	COG1187	pseudouridine synthase activity
DZA53_13375	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DZA53_13380	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DZA53_13385	COG2350	Protein conserved in bacteria
DZA53_13415	COG1175	transmembrane transport
DZA53_13420	COG0395	ABC-type sugar transport system, permease component
DZA53_13445	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DZA53_13455	COG2957	Belongs to the agmatine deiminase family
DZA53_13465	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DZA53_13475	COG0539	negative regulation of cytoplasmic translation
DZA53_13490	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
DZA53_13495	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DZA53_13505	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DZA53_13545	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DZA53_13550	COG0583	DNA-binding transcription factor activity
DZA53_13580	COG0583	DNA-binding transcription factor activity
DZA53_13595	COG2201	protein-glutamate methylesterase activity
DZA53_13605	COG1914	H( )-stimulated, divalent metal cation uptake system
DZA53_13610	COG1321	iron dependent repressor
DZA53_13615	COG0590	tRNA wobble adenosine to inosine editing
DZA53_13625	COG0668	transmembrane transport
DZA53_13650	COG1028	Short-chain dehydrogenase reductase Sdr
DZA53_13655	COG1183	phosphatidylcholine synthase activity
DZA53_13665	COG3243	poly(R)-hydroxyalkanoic acid synthase
DZA53_13680	COG0723	plastoquinol--plastocyanin reductase activity
DZA53_13680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DZA53_13690	COG2183	response to ionizing radiation
DZA53_13705	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
DZA53_13720	COG0671	phosphoesterase, PA-phosphatase related
DZA53_13745	COG1794	racemase activity, acting on amino acids and derivatives
DZA53_13755	COG0697	spore germination
DZA53_13780	COG1012	belongs to the aldehyde dehydrogenase family
DZA53_13825	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DZA53_13840	COG0124	histidyl-tRNA synthetase
DZA53_13905	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DZA53_13905	COG0140	phosphoribosyl-ATP diphosphatase activity
DZA53_13995	COG0653	protein targeting
DZA53_14035	COG2801	Transposase and inactivated derivatives
DZA53_14055	COG3328	transposase activity
DZA53_14100	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DZA53_14125	COG0811	peptide transport
DZA53_14155	COG4591	ABC-type transport system involved in lipoprotein release permease component
DZA53_14170	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DZA53_14185	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
DZA53_14200	COG0354	folic acid binding
DZA53_14215	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DZA53_14225	COG0363	glucosamine-6-phosphate deaminase activity
DZA53_14230	COG0129	dihydroxy-acid dehydratase activity
DZA53_14235	COG0800	Aldolase
DZA53_14270	COG0784	Response regulator, receiver
DZA53_14270	COG2205	protein histidine kinase activity
DZA53_14270	COG5002	protein histidine kinase activity
DZA53_14315	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DZA53_14320	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DZA53_14325	COG0431	NADPH-dependent FMN reductase
DZA53_14330	COG1393	Belongs to the ArsC family
DZA53_14335	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DZA53_14350	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DZA53_14380	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DZA53_14405	COG1247	-acetyltransferase
DZA53_14430	COG3706	GGDEF domain
DZA53_14485	COG0386	Belongs to the glutathione peroxidase family
DZA53_14575	COG5001	Diguanylate cyclase
DZA53_14575	COG4251	negative regulation of phosphorylation
DZA53_14575	COG2203	Gaf domain
DZA53_14575	COG3706	GGDEF domain
DZA53_14595	COG1472	Belongs to the glycosyl hydrolase 3 family
DZA53_14620	COG0166	Belongs to the GPI family
DZA53_14630	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DZA53_14635	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DZA53_14645	COG0617	tRNA 3'-terminal CCA addition
DZA53_14660	COG0860	N-Acetylmuramoyl-L-alanine amidase
DZA53_14710	COG4566	intracellular signal transduction
DZA53_14755	COG1605	Chorismate mutase
DZA53_14755	COG0077	Prephenate dehydratase
DZA53_14760	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DZA53_14765	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DZA53_14815	COG2986	histidine ammonia-lyase
DZA53_14825	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DZA53_14865	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
DZA53_14880	COG3115	cell septum assembly
DZA53_14905	COG0316	Belongs to the HesB IscA family
DZA53_14940	COG0288	reversible hydration of carbon dioxide
DZA53_14960	COG3844	kynureninase activity
DZA53_14970	COG2925	Exonuclease
DZA53_14980	COG0667	Aldo Keto reductase
DZA53_15050	COG0494	nUDIX hydrolase
DZA53_15060	COG1024	Enoyl-CoA hydratase
DZA53_15070	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DZA53_15105	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DZA53_15110	COG0573	inorganic phosphate transmembrane transporter activity
DZA53_15125	COG0704	Plays a role in the regulation of phosphate uptake
DZA53_15135	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DZA53_15155	COG3328	transposase activity
DZA53_15185	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DZA53_15195	COG1862	Preprotein translocase
DZA53_15240	COG3039	Transposase
DZA53_15315	COG0405	Gamma-glutamyltransferase
DZA53_15320	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DZA53_15340	COG0742	ribosomal rna small subunit methyltransferase
DZA53_15455	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DZA53_15460	COG4988	ABC transporter
DZA53_15470	COG1271	oxidase subunit
DZA53_15535	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DZA53_15540	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DZA53_15550	COG0137	argininosuccinate synthase activity
DZA53_15555	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DZA53_15570	COG2166	iron-sulfur cluster assembly
DZA53_15585	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DZA53_15595	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DZA53_15630	COG3039	Transposase
DZA53_15655	COG4677	pectinesterase activity
DZA53_15690	COG0402	S-adenosylhomocysteine deaminase activity
DZA53_15705	COG1509	lysine 2,3-aminomutase activity
DZA53_15710	COG3300	MHYT domain
DZA53_15710	COG5001	Diguanylate cyclase
DZA53_15725	COG0483	inositol monophosphate 1-phosphatase activity
DZA53_15760	COG0513	Belongs to the DEAD box helicase family
DZA53_15765	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DZA53_15780	COG0625	glutathione transferase activity
DZA53_15795	COG4681	YaeQ
DZA53_15800	COG2081	HI0933 family
DZA53_15810	COG0501	Belongs to the peptidase M48B family
DZA53_15820	COG1028	Short-chain dehydrogenase reductase Sdr
DZA53_15850	COG0860	N-Acetylmuramoyl-L-alanine amidase
DZA53_15855	COG0802	atpase or kinase
DZA53_15860	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DZA53_15860	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DZA53_15865	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DZA53_15885	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DZA53_15970	COG3328	transposase activity
DZA53_16015	COG2969	positive regulation of protein catabolic process
DZA53_16020	COG0625	glutathione transferase activity
DZA53_16025	COG2857	Cytochrome c1
DZA53_16030	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DZA53_16035	COG0723	plastoquinol--plastocyanin reductase activity
DZA53_16045	COG0741	lytic transglycosylase activity
DZA53_16070	COG1702	phosphate starvation-inducible protein PhoH
DZA53_16090	COG4535	Mg2 and Co2 transporter CorC
DZA53_16105	COG1012	belongs to the aldehyde dehydrogenase family
DZA53_16115	COG1177	transmembrane transport
DZA53_16170	COG0174	glutamine synthetase
DZA53_16175	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DZA53_16180	COG3706	GGDEF domain
DZA53_16180	COG0745	RESPONSE REGULATOR receiver
DZA53_16185	COG0477	Major facilitator Superfamily
DZA53_16200	COG0243	molybdopterin cofactor binding
DZA53_16225	COG1121	(ABC) transporter
DZA53_16235	COG2733	membrane
DZA53_16240	COG2205	protein histidine kinase activity
DZA53_16240	COG0784	Response regulator, receiver
DZA53_16240	COG5002	protein histidine kinase activity
DZA53_16250	COG3039	Transposase
DZA53_16260	COG2902	Dehydrogenase
DZA53_16270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DZA53_16275	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DZA53_16295	COG1609	Transcriptional regulator
DZA53_16300	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DZA53_16300	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DZA53_16305	COG1105	Belongs to the carbohydrate kinase PfkB family
DZA53_16310	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DZA53_16310	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DZA53_16325	COG3039	Transposase
DZA53_16335	COG3039	Transposase
DZA53_16360	COG3039	Transposase
DZA53_16405	COG3501	Rhs element vgr protein
DZA53_16425	COG3501	Rhs element vgr protein
DZA53_16470	COG4771	TonB-dependent receptor
DZA53_16480	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DZA53_16500	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DZA53_16505	COG1360	Flagellar Motor Protein
DZA53_16510	COG1192	Involved in chromosome partitioning
DZA53_16515	COG0835	chemotaxis
DZA53_16525	COG0745	RESPONSE REGULATOR receiver
DZA53_16550	COG0840	transmembrane signaling receptor activity
DZA53_16565	COG0840	transmembrane signaling receptor activity
DZA53_16575	COG0840	transmembrane signaling receptor activity
DZA53_16585	COG0840	transmembrane signaling receptor activity
DZA53_16590	COG0840	transmembrane signaling receptor activity
DZA53_16595	COG0840	transmembrane signaling receptor activity
DZA53_16600	COG0840	transmembrane signaling receptor activity
DZA53_16625	COG0835	chemotaxis
DZA53_16650	COG0840	transmembrane signaling receptor activity
DZA53_16685	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DZA53_16715	COG0318	PFAM AMP-dependent synthetase and ligase
DZA53_16720	COG1024	Enoyl-CoA hydratase
DZA53_16725	COG2205	protein histidine kinase activity
DZA53_16725	COG2198	Histidine kinase
DZA53_16725	COG0784	Response regulator, receiver
DZA53_16740	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DZA53_16800	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DZA53_16810	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DZA53_16815	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DZA53_16825	COG0505	Belongs to the CarA family
DZA53_16830	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DZA53_16840	COG2258	MOSC domain
DZA53_16845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DZA53_16915	COG0477	Major facilitator Superfamily
DZA53_16925	COG1070	Carbohydrate kinase
DZA53_16935	COG1501	Belongs to the glycosyl hydrolase 31 family
DZA53_16950	COG0800	Aldolase
DZA53_16965	COG3734	2-keto-3-deoxy-galactonokinase
DZA53_16970	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DZA53_16980	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DZA53_16995	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DZA53_17000	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DZA53_17010	COG0351	phosphomethylpyrimidine kinase
DZA53_17040	COG0583	DNA-binding transcription factor activity
DZA53_17045	COG1741	Belongs to the pirin family
DZA53_17070	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DZA53_17075	COG0305	Participates in initiation and elongation during chromosome replication
DZA53_17095	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
DZA53_17105	COG2137	regulation of response to DNA damage stimulus
DZA53_17130	COG1546	Belongs to the CinA family
DZA53_17135	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DZA53_17140	COG1923	regulation of RNA biosynthetic process
DZA53_17145	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DZA53_17150	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DZA53_17155	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DZA53_17165	COG1534	Rna-binding protein
DZA53_17180	COG1238	metal cluster binding
DZA53_17195	COG2840	Smr protein MutS2
DZA53_17220	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DZA53_17275	COG0306	phosphate transporter
DZA53_17290	COG1253	flavin adenine dinucleotide binding
DZA53_17305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DZA53_17325	COG0477	Major facilitator Superfamily
DZA53_17335	COG1132	(ABC) transporter
DZA53_17340	COG1136	(ABC) transporter
DZA53_17355	COG0438	transferase activity, transferring glycosyl groups
DZA53_17365	COG2264	protein methyltransferase activity
DZA53_17395	COG2244	polysaccharide biosynthetic process
DZA53_17445	COG1595	DNA-templated transcription, initiation
DZA53_17460	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DZA53_17480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DZA53_17530	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DZA53_17535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DZA53_17595	COG1858	cytochrome C peroxidase
DZA53_17625	COG0515	serine threonine protein kinase
DZA53_17630	COG0631	protein serine/threonine phosphatase activity
DZA53_17665	COG3501	Rhs element vgr protein
DZA53_17725	COG3039	Transposase
DZA53_17735	COG3501	Rhs element vgr protein
DZA53_17775	COG3039	Transposase
DZA53_17800	COG3039	Transposase
DZA53_17825	COG3039	Transposase
DZA53_17830	COG3209	COG3209 Rhs family protein
DZA53_17830	COG3209	COG3209 Rhs family protein
DZA53_17870	COG3209	COG3209 Rhs family protein
DZA53_17870	COG3209	COG3209 Rhs family protein
DZA53_17880	COG3501	Rhs element vgr protein
DZA53_17890	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DZA53_17895	COG1845	cytochrome c oxidase, subunit III
DZA53_17900	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DZA53_17930	COG0196	riboflavin kinase activity
DZA53_17935	COG0728	peptidoglycan biosynthetic process
DZA53_17940	COG0268	Binds directly to 16S ribosomal RNA
DZA53_17960	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DZA53_17965	COG0824	Thioesterase
DZA53_17980	COG1946	Acyl-CoA thioesterase
DZA53_17990	COG1595	DNA-templated transcription, initiation
DZA53_18045	COG1877	trehalose-phosphatase activity
DZA53_18050	COG3387	PFAM Glycoside hydrolase 15-related
DZA53_18075	COG0564	pseudouridine synthase activity
DZA53_18080	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DZA53_18085	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DZA53_18085	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DZA53_18095	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DZA53_18120	COG2184	nucleotidyltransferase activity
DZA53_18140	COG2194	sulfuric ester hydrolase activity
DZA53_18145	COG4969	Belongs to the N-Me-Phe pilin family
DZA53_18155	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DZA53_18210	COG3039	Transposase
DZA53_18220	COG3209	COG3209 Rhs family protein
DZA53_18260	COG1132	(ABC) transporter
DZA53_18290	COG0745	RESPONSE REGULATOR receiver
DZA53_18295	COG5000	phosphorelay sensor kinase activity
DZA53_18295	COG5002	protein histidine kinase activity
DZA53_18300	COG0475	glutathione-regulated potassium exporter activity
DZA53_18335	COG1187	pseudouridine synthase activity
DZA53_18340	COG5001	Diguanylate cyclase
DZA53_18340	COG5002	protein histidine kinase activity
DZA53_18440	COG1028	Short-chain dehydrogenase reductase Sdr
DZA53_18460	COG0415	Belongs to the DNA photolyase family
DZA53_18465	COG0305	Participates in initiation and elongation during chromosome replication
DZA53_18475	COG0367	asparagine synthase
DZA53_18490	COG1960	acyl-CoA dehydrogenase activity
DZA53_18505	COG0084	hydrolase, TatD family'
DZA53_18510	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DZA53_18570	COG0735	belongs to the Fur family
DZA53_18590	COG3039	Transposase
DZA53_18615	COG3039	Transposase
DZA53_18655	COG3039	Transposase
DZA53_18695	COG2205	protein histidine kinase activity
DZA53_18710	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
DZA53_18720	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DZA53_18730	COG0643	Histidine kinase
DZA53_18730	COG2198	Histidine kinase
DZA53_18740	COG0840	transmembrane signaling receptor activity
DZA53_18745	COG0835	chemotaxis
DZA53_18750	COG2202	Pas domain
DZA53_18750	COG2200	EAL domain
DZA53_18750	COG2199	diguanylate cyclase activity
DZA53_18755	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DZA53_18770	COG3590	peptidase
DZA53_18790	COG0588	phosphoglycerate mutase activity
DZA53_18795	COG1515	deoxyribonuclease V activity
DZA53_18805	COG1741	Belongs to the pirin family
DZA53_18830	COG3039	Transposase
DZA53_18840	COG3039	Transposase
DZA53_18875	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DZA53_18895	COG3501	Rhs element vgr protein
DZA53_18950	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DZA53_18975	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
DZA53_18990	COG2197	response regulator
DZA53_18995	COG4585	Histidine kinase
DZA53_19015	COG2894	cell division
DZA53_19020	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
DZA53_19030	COG0642	Histidine kinase
DZA53_19035	COG0745	RESPONSE REGULATOR receiver
DZA53_19040	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DZA53_19050	COG2194	sulfuric ester hydrolase activity
DZA53_19080	COG3551	Protein conserved in bacteria
DZA53_19145	COG0203	ribosomal protein L17
DZA53_19150	COG0202	RNA polymerase activity
DZA53_19165	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DZA53_19170	COG0201	protein transport
DZA53_19180	COG1841	ribosomal large subunit assembly
DZA53_19185	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DZA53_19190	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DZA53_19205	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DZA53_19215	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DZA53_19225	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DZA53_19230	COG0255	Belongs to the universal ribosomal protein uL29 family
DZA53_19235	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DZA53_19260	COG0089	rRNA binding
DZA53_19305	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DZA53_19330	COG0081	regulation of translation
DZA53_19345	COG0250	Participates in transcription elongation, termination and antitermination
DZA53_19350	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DZA53_19380	COG0012	GTP binding
DZA53_19395	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DZA53_19420	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DZA53_19435	COG0521	Mo-molybdopterin cofactor biosynthetic process
DZA53_19455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DZA53_19490	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DZA53_19495	COG1404	Belongs to the peptidase S8 family
DZA53_19510	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DZA53_19540	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
DZA53_19545	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
DZA53_19565	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
DZA53_19580	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DZA53_19580	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DZA53_19620	COG2890	protein-(glutamine-N5) methyltransferase activity
DZA53_19630	COG3634	alkyl hydroperoxide reductase activity
DZA53_19635	COG0583	DNA-binding transcription factor activity
DZA53_19645	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DZA53_19650	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DZA53_19680	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DZA53_19720	COG0745	RESPONSE REGULATOR receiver
DZA53_19720	COG3706	GGDEF domain
DZA53_19805	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
DZA53_19815	COG3386	PFAM SMP-30 Gluconolaconase
DZA53_19835	COG1024	Enoyl-CoA hydratase
DZA53_19845	COG0318	PFAM AMP-dependent synthetase and ligase
DZA53_19850	COG0583	DNA-binding transcription factor activity
DZA53_19890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DZA53_19895	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DZA53_19905	COG2096	Adenosyltransferase
DZA53_19910	COG0123	including yeast histone deacetylase and acetoin utilization protein
DZA53_19925	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DZA53_19985	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DZA53_20005	COG0642	Histidine kinase
DZA53_20020	COG4181	ATPase activity
DZA53_20030	COG2175	clavaminate synthase activity
DZA53_20080	COG0667	Aldo Keto reductase
DZA53_20090	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DZA53_20095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DZA53_20115	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DZA53_20130	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DZA53_20185	COG2226	methyltransferase
DZA53_20240	COG3321	synthase
DZA53_20240	COG0604	alcohol dehydrogenase
DZA53_20240	COG1028	Short-chain dehydrogenase reductase Sdr
DZA53_20255	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DZA53_20270	COG0494	nUDIX hydrolase
DZA53_20280	COG0653	protein targeting
DZA53_20285	COG4942	peptidase
DZA53_20285	COG1388	LysM domain
DZA53_20310	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DZA53_20315	COG1181	Belongs to the D-alanine--D-alanine ligase family
DZA53_20335	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DZA53_20340	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DZA53_20355	COG3116	cell division
DZA53_20400	COG1988	membrane-bound metal-dependent
DZA53_20405	COG0277	FAD linked oxidase domain protein
DZA53_20410	COG0745	RESPONSE REGULATOR receiver
DZA53_20415	COG2205	protein histidine kinase activity
DZA53_20425	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DZA53_20430	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DZA53_20455	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DZA53_20485	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DZA53_20485	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DZA53_20525	COG0488	(ABC) transporter
DZA53_20575	COG0745	RESPONSE REGULATOR receiver
DZA53_20580	COG2205	protein histidine kinase activity
DZA53_20660	COG3039	Transposase
DZA53_20675	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DZA53_20760	COG3039	Transposase
DZA53_20815	COG1649	PFAM Uncharacterised BCR, COG1649
DZA53_20815	COG0726	polysaccharide deacetylase
DZA53_20820	COG1215	transferase activity, transferring glycosyl groups
DZA53_20830	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DZA53_20835	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DZA53_20840	COG1609	Transcriptional regulator
DZA53_20865	COG3250	beta-galactosidase activity
DZA53_20915	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DZA53_20920	COG4191	Histidine kinase
DZA53_20925	COG0784	Response regulator, receiver
DZA53_20930	COG4251	negative regulation of phosphorylation
DZA53_20935	COG2823	Periplasmic or secreted lipoprotein
DZA53_20940	COG0673	inositol 2-dehydrogenase activity
DZA53_20945	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
DZA53_20980	COG1051	belongs to the nudix hydrolase family
DZA53_20980	COG1056	cytidyltransferase-related domain
DZA53_21020	COG1686	Belongs to the peptidase S11 family
DZA53_21030	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DZA53_21035	COG2951	lytic endotransglycosylase activity
DZA53_21050	COG3409	Peptidoglycan-binding domain 1 protein
DZA53_21050	COG5632	N-Acetylmuramoyl-L-alanine amidase
DZA53_21050	COG1388	LysM domain
DZA53_21085	COG0772	Belongs to the SEDS family
DZA53_21100	COG1792	Involved in formation and maintenance of cell shape
DZA53_21105	COG1077	Cell shape determining protein MreB Mrl
DZA53_21155	COG2199	diguanylate cyclase activity
DZA53_21160	COG0308	aminopeptidase N
DZA53_21190	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DZA53_21235	COG1505	serine-type exopeptidase activity
DZA53_21270	COG3275	phosphorelay sensor kinase activity
DZA53_21325	COG0659	secondary active sulfate transmembrane transporter activity
DZA53_21330	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DZA53_21330	COG5297	Belongs to the glycosyl hydrolase family 6
DZA53_21395	COG3039	Transposase
DZA53_21415	COG0598	Magnesium transport protein CorA
DZA53_21425	COG1113	amino acid transport
DZA53_21435	COG5297	Belongs to the glycosyl hydrolase family 6
DZA53_21440	COG4305	rare lipoprotein A
DZA53_21445	COG0697	spore germination
DZA53_21505	COG4221	oxidoreductase activity
DZA53_21535	COG0456	acetyltransferase
DZA53_21545	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
DZA53_21590	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DZA53_21590	COG2111	Na H antiporter
DZA53_21595	COG1006	Multisubunit Na H antiporter MnhC subunit
DZA53_21600	COG0651	ATP synthesis coupled electron transport
DZA53_21610	COG2212	antiporter activity
DZA53_21615	COG1320	monovalent cation:proton antiporter activity
DZA53_21630	COG3039	Transposase
DZA53_21655	COG3104	oligopeptide transport
DZA53_21670	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DZA53_21705	COG0183	Belongs to the thiolase family
DZA53_21775	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
DZA53_21780	COG3023	N-Acetylmuramoyl-L-alanine amidase
DZA53_21790	COG4948	Mandelate Racemase Muconate Lactonizing
DZA53_21825	COG0531	amino acid
DZA53_21855	COG4682	membrane
DZA53_21860	COG2133	pyrroloquinoline quinone binding
DZA53_21900	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DZA53_21910	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DZA53_21915	COG1610	YqeY-like protein
DZA53_21935	COG1295	ribonuclease BN
DZA53_21940	COG0358	DNA primase activity
DZA53_22085	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DZA53_22095	COG1560	Kdo2-lipid A biosynthetic process
DZA53_22145	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DZA53_22145	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DZA53_22155	COG0242	peptide deformylase activity
DZA53_22160	COG1652	LysM domain
DZA53_22165	COG0758	DNA mediated transformation
DZA53_22185	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DZA53_22185	COG1754	DNA topoisomerase type I activity
DZA53_22205	COG1028	Short-chain dehydrogenase reductase Sdr
DZA53_22215	COG0616	signal peptide processing
DZA53_22220	COG0534	Mate efflux family protein
DZA53_22250	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DZA53_22285	COG1324	tolerance protein
DZA53_22310	COG0511	ligase activity, forming carbon-carbon bonds
DZA53_22320	COG0439	Biotin carboxylase
DZA53_22380	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
DZA53_22445	COG2831	hemolysin activation secretion protein
DZA53_22470	COG2453	phosphatase
DZA53_22470	COG0671	phosphoesterase, PA-phosphatase related
DZA53_22475	COG2267	carboxylic ester hydrolase activity
DZA53_22485	COG2267	carboxylic ester hydrolase activity
DZA53_22495	COG0138	bifunctional purine biosynthesis protein purh
DZA53_22500	COG0151	Belongs to the GarS family
DZA53_22505	COG1136	(ABC) transporter
DZA53_22505	COG0577	efflux transmembrane transporter activity
DZA53_22515	COG1289	transmembrane transporter activity
DZA53_22530	COG2814	Major facilitator Superfamily
DZA53_22555	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DZA53_22635	COG0739	heme binding
DZA53_22650	COG2211	Major facilitator Superfamily
DZA53_22655	COG0708	Exodeoxyribonuclease III
DZA53_22670	COG1192	Involved in chromosome partitioning
DZA53_22675	COG1475	DNA binding
DZA53_22690	COG0463	Glycosyl transferase, family 2
DZA53_22710	COG0756	dUTP diphosphatase activity
DZA53_22715	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DZA53_22720	COG2003	Belongs to the UPF0758 family
DZA53_22725	COG0018	arginyl-trna synthetase
DZA53_22740	COG4221	oxidoreductase activity
DZA53_22765	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DZA53_22770	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DZA53_22785	COG3485	protocatechuate 3,4-dioxygenase
DZA53_22790	COG3485	protocatechuate 3,4-dioxygenase
DZA53_22830	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DZA53_22840	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DZA53_22855	COG1042	CoA-binding domain protein
DZA53_22855	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DZA53_22855	COG0045	succinate-CoA ligase (ADP-forming) activity
DZA53_22865	COG2239	Acts as a magnesium transporter
DZA53_22885	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DZA53_22905	COG3100	YcgL domain-containing protein
DZA53_22910	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DZA53_22920	COG0463	Glycosyl transferase, family 2
DZA53_22935	COG1028	Short-chain dehydrogenase reductase Sdr
DZA53_22960	COG1040	competence protein
DZA53_22980	COG0628	permease
DZA53_22990	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DZA53_23000	COG1595	DNA-templated transcription, initiation
DZA53_23005	COG0753	catalase activity
DZA53_23050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DZA53_23055	COG0180	Tryptophanyl-tRNA synthetase
DZA53_23060	COG3237	CsbD-like
DZA53_23120	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
DZA53_23120	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
DZA53_23145	COG2205	protein histidine kinase activity
DZA53_23150	COG0745	RESPONSE REGULATOR receiver
DZA53_23160	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DZA53_23190	COG1566	PFAM secretion protein HlyD family protein
DZA53_23210	COG1199	ATP-dependent helicase activity
DZA53_23245	COG0583	DNA-binding transcription factor activity
DZA53_23295	COG0625	glutathione transferase activity
DZA53_23330	COG4555	ABC transporter
DZA53_23340	COG1476	TRANSCRIPTIONal
DZA53_23365	COG1131	(ABC) transporter
DZA53_23370	COG0842	Transport permease protein
DZA53_23380	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DZA53_23465	COG1181	Belongs to the D-alanine--D-alanine ligase family
DZA53_23490	COG0564	pseudouridine synthase activity
DZA53_23520	COG0339	signal peptide processing
DZA53_23550	COG3254	rhamnose metabolic process
DZA53_23555	COG0738	Major facilitator superfamily
DZA53_23560	COG1414	Transcriptional regulator
DZA53_23575	COG2205	protein histidine kinase activity
DZA53_23590	COG3459	Glycosyltransferase 36 associated
DZA53_23595	COG2211	Major facilitator Superfamily
DZA53_23600	COG3265	gluconokinase activity
DZA53_23610	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DZA53_23700	COG1127	ABC transporter
DZA53_23705	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DZA53_23710	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DZA53_23725	COG2853	Lipoprotein
DZA53_23815	COG0676	glucose-6-phosphate 1-epimerase activity
DZA53_23840	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DZA53_23850	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DZA53_23860	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DZA53_23870	COG1064	alcohol dehydrogenase
DZA53_23915	COG1522	sequence-specific DNA binding
DZA53_23920	COG3186	Phenylalanine-4-hydroxylase
DZA53_23935	COG2755	lipolytic protein G-D-S-L family
DZA53_23960	COG0656	L-ascorbic acid biosynthetic process
DZA53_23965	COG2130	NADP-dependent
DZA53_23970	COG0667	Aldo Keto reductase
DZA53_23980	COG1187	pseudouridine synthase activity
DZA53_23995	COG1643	Atp-dependent helicase
DZA53_24000	COG4807	Protein conserved in bacteria
DZA53_24005	COG4948	Mandelate Racemase Muconate Lactonizing
DZA53_24015	COG0179	Fumarylacetoacetate (FAA) hydrolase
DZA53_24020	COG1028	Short-chain dehydrogenase reductase Sdr
DZA53_24040	COG3507	Belongs to the glycosyl hydrolase 43 family
DZA53_24085	COG3162	membrane
DZA53_24090	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DZA53_24105	COG0708	Exodeoxyribonuclease III
DZA53_24120	COG2091	lysine biosynthetic process via aminoadipic acid
DZA53_24130	COG3540	Alkaline phosphatase
DZA53_24135	COG0357	Ribosomal RNA small subunit methyltransferase G
DZA53_24150	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DZA53_24155	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DZA53_24160	COG2159	amidohydrolase
DZA53_24175	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DZA53_24180	COG0583	DNA-binding transcription factor activity
DZA53_24185	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DZA53_24205	COG0210	DNA helicase
DZA53_24220	COG0531	amino acid
DZA53_24235	COG1322	Protein conserved in bacteria
DZA53_24250	COG0386	Belongs to the glutathione peroxidase family
DZA53_24305	COG0793	Belongs to the peptidase S41A family
DZA53_24310	COG4942	peptidase
DZA53_24320	COG2234	aminopeptidase activity
DZA53_24370	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DZA53_24375	COG0302	gtp cyclohydrolase
DZA53_24395	COG0477	Major facilitator Superfamily
DZA53_24405	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DZA53_24480	COG1192	Involved in chromosome partitioning
DZA53_24515	COG1929	Belongs to the glycerate kinase type-1 family
DZA53_24520	COG2271	Major facilitator Superfamily
DZA53_24535	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DZA53_24545	COG0861	Integral membrane protein TerC family
DZA53_24555	COG0584	glycerophosphoryl diester phosphodiesterase
DZA53_24565	COG0671	phosphoesterase, PA-phosphatase related
DZA53_24570	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DZA53_24575	COG0726	polysaccharide deacetylase
DZA53_24580	COG0706	membrane insertase activity
DZA53_24590	COG0230	Belongs to the bacterial ribosomal protein bL34 family