locus-tag	class	description
BHL62_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BHL62_00030	COG0187	DNA topoisomerase II activity
BHL62_00040	COG0501	Belongs to the peptidase M48B family
BHL62_00070	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BHL62_00080	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BHL62_00090	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BHL62_00100	COG4772	TonB-dependent receptor
BHL62_00115	COG3039	Transposase
BHL62_00120	COG1304	FMN binding
BHL62_00140	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BHL62_00150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BHL62_00185	COG3039	Transposase
BHL62_00260	COG2826	transposase and inactivated derivatives, IS30 family
BHL62_00285	COG3039	Transposase
BHL62_00295	COG1090	epimerase
BHL62_00300	COG0642	Histidine kinase
BHL62_00310	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BHL62_00410	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BHL62_00470	COG3328	transposase activity
BHL62_00495	COG3264	Mechanosensitive ion channel
BHL62_00495	COG1511	domain protein
BHL62_00505	COG3293	Transposase
BHL62_00515	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BHL62_00525	COG2354	Protein conserved in bacteria
BHL62_00530	COG1649	PFAM Uncharacterised BCR, COG1649
BHL62_00550	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BHL62_00575	COG0702	epimerase
BHL62_00585	COG1858	cytochrome C peroxidase
BHL62_00655	COG0513	Belongs to the DEAD box helicase family
BHL62_00665	COG3039	Transposase
BHL62_00710	COG1116	anion transmembrane transporter activity
BHL62_00730	COG3039	Transposase
BHL62_00745	COG1136	(ABC) transporter
BHL62_00760	COG2826	transposase and inactivated derivatives, IS30 family
BHL62_00790	COG1272	protein, Hemolysin III
BHL62_00795	COG1111	helicase
BHL62_00795	COG1205	dead DEAH box helicase
BHL62_00865	COG0067	glutamate synthase
BHL62_00865	COG0069	glutamate synthase activity
BHL62_00865	COG0070	glutamate synthase
BHL62_00870	COG0493	'glutamate synthase
BHL62_00895	COG2826	transposase and inactivated derivatives, IS30 family
BHL62_00940	COG1609	Transcriptional regulator
BHL62_00975	COG0366	Alpha amylase catalytic
BHL62_00980	COG0366	Alpha amylase catalytic
BHL62_01115	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BHL62_01120	COG3265	gluconokinase activity
BHL62_01125	COG2211	Major facilitator Superfamily
BHL62_01130	COG3459	Glycosyltransferase 36 associated
BHL62_01145	COG2205	protein histidine kinase activity
BHL62_01155	COG3293	Transposase
BHL62_01165	COG1414	Transcriptional regulator
BHL62_01170	COG0738	Major facilitator superfamily
BHL62_01175	COG3254	rhamnose metabolic process
BHL62_01210	COG0339	signal peptide processing
BHL62_01235	COG0564	pseudouridine synthase activity
BHL62_01245	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BHL62_01260	COG1181	Belongs to the D-alanine--D-alanine ligase family
BHL62_01300	COG3293	Transposase
BHL62_01315	COG2801	Transposase and inactivated derivatives
BHL62_01360	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BHL62_01370	COG0842	Transport permease protein
BHL62_01375	COG1131	(ABC) transporter
BHL62_01380	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BHL62_01400	COG1476	TRANSCRIPTIONal
BHL62_01410	COG4555	ABC transporter
BHL62_01445	COG0625	glutathione transferase activity
BHL62_01500	COG3293	Transposase
BHL62_01515	COG0583	DNA-binding transcription factor activity
BHL62_01555	COG3039	Transposase
BHL62_01565	COG3293	Transposase
BHL62_01575	COG3293	Transposase
BHL62_01625	COG3039	Transposase
BHL62_01635	COG3039	Transposase
BHL62_01645	COG1199	ATP-dependent helicase activity
BHL62_01665	COG3293	Transposase
BHL62_01760	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BHL62_01790	COG3228	Belongs to the MtfA family
BHL62_01805	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BHL62_01805	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BHL62_01810	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BHL62_01825	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BHL62_01865	COG3237	CsbD-like
BHL62_01870	COG0180	Tryptophanyl-tRNA synthetase
BHL62_01875	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BHL62_01925	COG0753	catalase activity
BHL62_01930	COG1595	DNA-templated transcription, initiation
BHL62_01940	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BHL62_01950	COG0628	permease
BHL62_01965	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BHL62_01970	COG1040	competence protein
BHL62_01975	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BHL62_01980	COG0156	8-amino-7-oxononanoate synthase activity
BHL62_01995	COG1028	Short-chain dehydrogenase reductase Sdr
BHL62_02005	COG3293	Transposase
BHL62_02020	COG0463	Glycosyl transferase, family 2
BHL62_02030	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BHL62_02035	COG3100	YcgL domain-containing protein
BHL62_02050	COG3387	PFAM Glycoside hydrolase 15-related
BHL62_02055	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BHL62_02070	COG2239	Acts as a magnesium transporter
BHL62_02080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BHL62_02080	COG1042	CoA-binding domain protein
BHL62_02080	COG0045	succinate-CoA ligase (ADP-forming) activity
BHL62_02095	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BHL62_02105	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BHL62_02145	COG3485	protocatechuate 3,4-dioxygenase
BHL62_02150	COG3485	protocatechuate 3,4-dioxygenase
BHL62_02160	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BHL62_02165	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BHL62_02170	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BHL62_02180	COG1414	Transcriptional regulator
BHL62_02195	COG4221	oxidoreductase activity
BHL62_02220	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BHL62_02245	COG0463	Glycosyl transferase, family 2
BHL62_02260	COG1475	DNA binding
BHL62_02265	COG1192	Involved in chromosome partitioning
BHL62_02280	COG0708	Exodeoxyribonuclease III
BHL62_02285	COG2211	Major facilitator Superfamily
BHL62_02300	COG0739	heme binding
BHL62_02345	COG0745	RESPONSE REGULATOR receiver
BHL62_02385	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BHL62_02405	COG2814	Major facilitator Superfamily
BHL62_02430	COG1289	transmembrane transporter activity
BHL62_02440	COG1136	(ABC) transporter
BHL62_02440	COG0577	efflux transmembrane transporter activity
BHL62_02445	COG0151	Belongs to the GarS family
BHL62_02465	COG2267	carboxylic ester hydrolase activity
BHL62_02475	COG2267	carboxylic ester hydrolase activity
BHL62_02480	COG2453	phosphatase
BHL62_02480	COG0671	phosphoesterase, PA-phosphatase related
BHL62_02495	COG3293	Transposase
BHL62_02520	COG3328	transposase activity
BHL62_02525	COG3328	transposase activity
BHL62_02545	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BHL62_02600	COG0439	Biotin carboxylase
BHL62_02610	COG0511	ligase activity, forming carbon-carbon bonds
BHL62_02615	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BHL62_02630	COG1324	tolerance protein
BHL62_02635	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BHL62_02655	COG0534	Mate efflux family protein
BHL62_02660	COG0616	signal peptide processing
BHL62_02670	COG1028	Short-chain dehydrogenase reductase Sdr
BHL62_02695	COG0009	L-threonylcarbamoyladenylate synthase
BHL62_02700	COG1754	DNA topoisomerase type I activity
BHL62_02700	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BHL62_02715	COG2922	Belongs to the Smg family
BHL62_02720	COG0758	DNA mediated transformation
BHL62_02725	COG1652	LysM domain
BHL62_02730	COG0242	peptide deformylase activity
BHL62_02735	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BHL62_02740	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BHL62_02740	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BHL62_02790	COG1560	Kdo2-lipid A biosynthetic process
BHL62_02800	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BHL62_02980	COG1294	oxidase, subunit
BHL62_02985	COG1271	oxidase subunit
BHL62_03000	COG2204	response regulator
BHL62_03035	COG2972	Histidine kinase
BHL62_03050	COG0531	amino acid
BHL62_03070	COG3590	peptidase
BHL62_03085	COG0667	Aldo Keto reductase
BHL62_03100	COG3384	dioxygenase
BHL62_03110	COG1573	uracil-dna glycosylase
BHL62_03120	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
BHL62_03135	COG0025	NhaP-type Na H and K H
BHL62_03140	COG1131	(ABC) transporter
BHL62_03145	COG0842	Transport permease protein
BHL62_03165	COG1404	Belongs to the peptidase S8 family
BHL62_03180	COG0745	RESPONSE REGULATOR receiver
BHL62_03230	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BHL62_03255	COG2202	Pas domain
BHL62_03255	COG2205	protein histidine kinase activity
BHL62_03270	COG3293	Transposase
BHL62_03305	COG2813	Specifically methylates the guanine in position
BHL62_03310	COG1187	pseudouridine synthase activity
BHL62_03315	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BHL62_03350	COG0697	spore germination
BHL62_03360	COG2011	ABC-type metal ion transport system permease component
BHL62_03390	COG0508	dehydrogenase complex catalyzes the overall conversion of
BHL62_03400	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BHL62_03420	COG0356	it plays a direct role in the translocation of protons across the membrane
BHL62_03430	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BHL62_03440	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BHL62_03445	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BHL62_03450	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BHL62_03510	COG1136	(ABC) transporter
BHL62_03515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BHL62_03520	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BHL62_03535	COG3293	Transposase
BHL62_03580	COG0339	signal peptide processing
BHL62_03620	COG1956	GAF domain-containing protein
BHL62_03625	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BHL62_03635	COG0720	synthase
BHL62_03645	COG0513	Belongs to the DEAD box helicase family
BHL62_03660	COG0625	glutathione transferase activity
BHL62_03690	COG0626	cystathionine gamma-synthase activity
BHL62_03710	COG0438	transferase activity, transferring glycosyl groups
BHL62_03710	COG1216	Glycosyl transferase, family 2
BHL62_03755	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
BHL62_03760	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BHL62_03775	COG0277	FAD linked oxidase domain protein
BHL62_03780	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BHL62_03780	COG0546	phosphoglycolate phosphatase activity
BHL62_03795	COG2086	electron transfer activity
BHL62_03820	COG0662	Cupin 2, conserved barrel domain protein
BHL62_03820	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BHL62_03825	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BHL62_03840	COG3293	Transposase
BHL62_03850	COG3039	Transposase
BHL62_03880	COG3218	ABC-type transport auxiliary lipoprotein component
BHL62_03880	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BHL62_03885	COG1127	ABC transporter
BHL62_03890	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BHL62_03905	COG0442	prolyl-tRNA aminoacylation
BHL62_03915	COG1183	phosphatidylcholine synthase activity
BHL62_03940	COG3039	Transposase
BHL62_03980	COG3039	Transposase
BHL62_03995	COG2801	Transposase and inactivated derivatives
BHL62_04020	COG0525	valine-tRNA ligase activity
BHL62_04035	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BHL62_04045	COG0795	lipopolysaccharide-transporting ATPase activity
BHL62_04060	COG4974	Belongs to the 'phage' integrase family
BHL62_04065	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BHL62_04075	COG0047	phosphoribosylformylglycinamidine synthase activity
BHL62_04075	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BHL62_04085	COG5295	Hep Hag repeat protein
BHL62_04095	COG1404	Belongs to the peptidase S8 family
BHL62_04100	COG1404	Belongs to the peptidase S8 family
BHL62_04105	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BHL62_04115	COG1459	type II secretion system
BHL62_04120	COG2165	general secretion pathway protein
BHL62_04125	COG4970	Tfp pilus assembly protein FimT
BHL62_04130	COG2165	general secretion pathway protein
BHL62_04135	COG4795	General secretion pathway protein
BHL62_04140	COG3156	type II secretion system protein K
BHL62_04145	COG3166	PFAM Fimbrial assembly family protein
BHL62_04160	COG1450	Type ii and iii secretion system protein
BHL62_04170	COG2188	Transcriptional regulator
BHL62_04225	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BHL62_04230	COG1518	maintenance of DNA repeat elements
BHL62_04275	COG1399	metal-binding, possibly nucleic acid-binding protein
BHL62_04300	COG1028	Short-chain dehydrogenase reductase Sdr
BHL62_04305	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BHL62_04315	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BHL62_04320	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BHL62_04345	COG3293	Transposase
BHL62_04360	COG3829	transcription factor binding
BHL62_04440	COG3039	Transposase
BHL62_04445	COG0678	peroxiredoxin activity
BHL62_04465	COG0330	HflC and HflK could
BHL62_04470	COG0330	HflC and HflK could
BHL62_04485	COG0308	aminopeptidase N
BHL62_04510	COG3328	transposase activity
BHL62_04535	COG1560	Kdo2-lipid A biosynthetic process
BHL62_04540	COG1519	Transferase
BHL62_04565	COG1538	Outer membrane efflux protein
BHL62_04570	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BHL62_04595	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BHL62_04600	COG0066	3-isopropylmalate dehydratase activity
BHL62_04635	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BHL62_04645	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BHL62_04650	COG3710	Transcriptional regulator
BHL62_04675	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BHL62_04720	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BHL62_04730	COG3781	membrane
BHL62_04760	COG3293	Transposase
BHL62_04835	COG2963	transposase activity
BHL62_04855	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BHL62_04875	COG1217	gtp-binding protein TYPA
BHL62_04880	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BHL62_04890	COG0625	glutathione transferase activity
BHL62_04910	COG3293	Transposase
BHL62_04935	COG2963	transposase activity
BHL62_04945	COG0446	pyridine nucleotide-disulphide oxidoreductase
BHL62_04945	COG1902	pentaerythritol trinitrate reductase activity
BHL62_04950	COG0604	alcohol dehydrogenase
BHL62_04980	COG0156	8-amino-7-oxononanoate synthase activity
BHL62_04985	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BHL62_04990	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BHL62_04995	COG4208	sulfate ABC transporter
BHL62_05000	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BHL62_05035	COG0406	alpha-ribazole phosphatase activity
BHL62_05045	COG0285	dihydrofolate synthase activity
BHL62_05065	COG2833	Protein of unknown function (DUF455)
BHL62_05085	COG3291	Pkd domain containing protein
BHL62_05095	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BHL62_05100	COG0671	phosphoesterase, PA-phosphatase related
BHL62_05105	COG0438	transferase activity, transferring glycosyl groups
BHL62_05115	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BHL62_05130	COG4783	chaperone-mediated protein folding
BHL62_05160	COG0473	3-isopropylmalate dehydrogenase activity
BHL62_05195	COG2963	transposase activity
BHL62_05205	COG1484	DNA-dependent DNA replication
BHL62_05220	COG0544	peptidyl-prolyl cis-trans isomerase activity
BHL62_05260	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BHL62_05285	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BHL62_05295	COG0631	protein serine/threonine phosphatase activity
BHL62_05350	COG0582	viral genome integration into host DNA
BHL62_05360	COG0859	PFAM glycosyl transferase family 9
BHL62_05365	COG3642	lipopolysaccharide core region biosynthetic process
BHL62_05370	COG1234	tRNA 3'-trailer cleavage
BHL62_05375	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BHL62_05385	COG0315	cyclic pyranopterin monophosphate synthase activity
BHL62_05390	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BHL62_05395	COG0314	molybdopterin synthase activity
BHL62_05425	COG0537	adenosine 5'-monophosphoramidase activity
BHL62_05445	COG0714	Associated with various cellular activities
BHL62_05465	COG0242	peptide deformylase activity
BHL62_05535	COG3039	Transposase
BHL62_05570	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BHL62_05575	COG0726	polysaccharide deacetylase
BHL62_05625	COG2211	Major facilitator Superfamily
BHL62_05635	COG1609	Transcriptional regulator
BHL62_05640	COG1028	Short-chain dehydrogenase reductase Sdr
BHL62_05645	COG2851	Citrate transporter
BHL62_05660	COG0642	Histidine kinase
BHL62_05670	COG2197	response regulator
BHL62_05690	COG0583	DNA-binding transcription factor activity
BHL62_05705	COG4191	Histidine kinase
BHL62_05725	COG0281	malic enzyme
BHL62_05725	COG0280	phosphate acetyltransferase
BHL62_05765	COG0352	thiamine-phosphate diphosphorylase activity
BHL62_05770	COG1773	rubredoxin
BHL62_05775	COG2912	Transglutaminase-like superfamily
BHL62_05795	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BHL62_05820	COG0006	proline dipeptidase activity
BHL62_05855	COG3293	Transposase
BHL62_05860	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BHL62_05875	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BHL62_05880	COG1561	YicC-like family, N-terminal region
BHL62_05910	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BHL62_05920	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BHL62_05950	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BHL62_05990	COG0714	Associated with various cellular activities
BHL62_06010	COG2304	oxidoreductase activity
BHL62_06030	COG1301	dicarboxylic acid transport
BHL62_06035	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BHL62_06040	COG4773	Receptor
BHL62_06045	COG0739	heme binding
BHL62_06050	COG1376	ErfK ybiS ycfS ynhG family protein
BHL62_06075	COG1022	Amp-dependent synthetase and ligase
BHL62_06085	COG1028	Short-chain dehydrogenase reductase Sdr
BHL62_06100	COG0642	Histidine kinase
BHL62_06120	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BHL62_06125	COG4149	molybdate abc transporter
BHL62_06130	COG0725	ABC transporter, periplasmic molybdate-binding protein
BHL62_06135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BHL62_06135	COG3453	Protein conserved in bacteria
BHL62_06170	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BHL62_06180	COG3039	Transposase
BHL62_06205	COG3293	Transposase
BHL62_06220	COG2205	protein histidine kinase activity
BHL62_06225	COG0745	RESPONSE REGULATOR receiver
BHL62_06240	COG3039	Transposase
BHL62_06280	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BHL62_06285	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BHL62_06335	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BHL62_06435	COG2201	protein-glutamate methylesterase activity
BHL62_06510	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BHL62_06525	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BHL62_06540	COG1842	Phage shock protein A
BHL62_06565	COG0754	glutathionylspermidine amidase activity
BHL62_06650	COG0531	amino acid
BHL62_06655	COG2197	response regulator
BHL62_06670	COG1113	amino acid transport
BHL62_06695	COG1271	oxidase subunit
BHL62_06700	COG1294	oxidase, subunit
BHL62_06710	COG2239	Acts as a magnesium transporter
BHL62_06720	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BHL62_06725	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BHL62_06735	COG1660	Displays ATPase and GTPase activities
BHL62_06740	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BHL62_06745	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BHL62_06760	COG1137	ATPase activity
BHL62_06765	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BHL62_06775	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BHL62_06785	COG0271	Belongs to the BolA IbaG family
BHL62_06790	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BHL62_06815	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BHL62_06830	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BHL62_06840	COG0628	permease
BHL62_06850	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BHL62_06855	COG3178	'Phosphotransferase
BHL62_06870	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BHL62_06875	COG1555	photosystem II stabilization
BHL62_06920	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BHL62_06935	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BHL62_06960	COG0228	four-way junction DNA binding
BHL62_06965	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BHL62_06970	COG0336	Belongs to the RNA methyltransferase TrmD family
BHL62_07015	COG0534	Mate efflux family protein
BHL62_07045	COG0542	response to heat
BHL62_07070	COG2963	transposase activity
BHL62_07090	COG4206	TonB-dependent receptor
BHL62_07150	COG0019	diaminopimelate decarboxylase activity
BHL62_07160	COG2814	Major facilitator Superfamily
BHL62_07165	COG4264	IucA IucC family
BHL62_07175	COG4772	TonB-dependent receptor
BHL62_07210	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BHL62_07210	COG4651	solute:proton antiporter activity
BHL62_07255	COG0488	(ABC) transporter
BHL62_07280	COG0657	acetylesterase activity
BHL62_07280	COG2755	lipolytic protein G-D-S-L family
BHL62_07295	COG3293	Transposase
BHL62_07310	COG2207	Transcriptional regulator
BHL62_07315	COG0326	Molecular chaperone. Has ATPase activity
BHL62_07345	COG3328	transposase activity
BHL62_07350	COG0174	glutamine synthetase
BHL62_07355	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BHL62_07365	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BHL62_07380	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BHL62_07400	COG2963	transposase activity
BHL62_07410	COG3039	Transposase
BHL62_07415	COG2146	nitrite reductase [NAD(P)H] activity
BHL62_07430	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BHL62_07435	COG0719	Fe-S assembly protein
BHL62_07440	COG0396	ATPase activity
BHL62_07445	COG0719	Fe-S assembly protein
BHL62_07450	COG1959	2 iron, 2 sulfur cluster binding
BHL62_07470	COG0693	protein deglycase activity
BHL62_07525	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BHL62_07555	COG0519	Catalyzes the synthesis of GMP from XMP
BHL62_07565	COG1678	Uncharacterized ACR, COG1678
BHL62_07570	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BHL62_07585	COG1764	response to oxidative stress
BHL62_07595	COG0384	phenazine biosynthesis protein PhzF
BHL62_07605	COG0527	aspartate kinase activity
BHL62_07635	COG0142	geranyltranstransferase activity
BHL62_07640	COG0629	single-stranded DNA binding
BHL62_07650	COG2203	Gaf domain
BHL62_07650	COG3706	GGDEF domain
BHL62_07650	COG4251	negative regulation of phosphorylation
BHL62_07650	COG5001	Diguanylate cyclase
BHL62_07680	COG2879	small protein
BHL62_07685	COG1966	Carbon starvation protein
BHL62_07690	COG1741	Belongs to the pirin family
BHL62_07780	COG3328	transposase activity
BHL62_07975	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
BHL62_07995	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BHL62_08000	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
BHL62_08005	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
BHL62_08010	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BHL62_08050	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BHL62_08095	COG0587	DNA-directed DNA polymerase activity
BHL62_08115	COG1297	OPT oligopeptide transporter protein
BHL62_08140	COG1506	peptidase
BHL62_08140	COG0823	Involved in the tonB-independent uptake of proteins
BHL62_08165	COG1917	Cupin 2, conserved barrel domain protein
BHL62_08165	COG2207	Transcriptional regulator
BHL62_08190	COG0753	catalase activity
BHL62_08235	COG0469	pyruvate kinase activity
BHL62_08245	COG3588	fructose-bisphosphate aldolase
BHL62_08250	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BHL62_08295	COG2205	protein histidine kinase activity
BHL62_08295	COG2198	Histidine kinase
BHL62_08295	COG0784	Response regulator, receiver
BHL62_08315	COG0175	sulfate reduction
BHL62_08320	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BHL62_08325	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BHL62_08330	COG0175	sulfate reduction
BHL62_08335	COG0529	Catalyzes the synthesis of activated sulfate
BHL62_08335	COG2895	sulfate adenylyltransferase (ATP) activity
BHL62_08345	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BHL62_08350	COG0308	aminopeptidase N
BHL62_08380	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BHL62_08395	COG3293	Transposase
BHL62_08410	COG1970	mechanosensitive ion channel activity
BHL62_08440	COG0471	metal ion transport
BHL62_08440	COG3273	potassium ion transport
BHL62_08450	COG2022	thiamine diphosphate biosynthetic process
BHL62_08580	COG3293	Transposase
BHL62_08595	COG3118	belongs to the thioredoxin family
BHL62_08625	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BHL62_08650	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BHL62_08675	COG2968	Membrane
BHL62_08690	COG3164	Protein of unknown function
BHL62_08700	COG0312	modulator of DNA gyrase
BHL62_08710	COG0312	modulator of DNA gyrase
BHL62_08735	COG0142	geranyltranstransferase activity
BHL62_08740	COG1722	exodeoxyribonuclease VII activity
BHL62_08745	COG0037	tRNA processing
BHL62_08750	COG1785	Belongs to the alkaline phosphatase family
BHL62_08770	COG0791	NLP P60 protein
BHL62_08775	COG0791	NLP P60 protein
BHL62_08780	COG1047	Peptidyl-prolyl cis-trans
BHL62_08785	COG2311	Membrane
BHL62_08790	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BHL62_08835	COG0489	protein tyrosine kinase activity
BHL62_08840	COG0717	Belongs to the dCTP deaminase family
BHL62_08855	COG0412	Dienelactone hydrolase
BHL62_08865	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BHL62_08885	COG0433	COG0433 Predicted ATPase
BHL62_08915	COG2890	protein-(glutamine-N5) methyltransferase activity
BHL62_08920	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BHL62_08925	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BHL62_08930	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BHL62_08955	COG0101	tRNA pseudouridine synthase activity
BHL62_08960	COG0135	phosphoribosylanthranilate isomerase activity
BHL62_08985	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BHL62_08990	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BHL62_09030	COG0149	triose-phosphate isomerase activity
BHL62_09045	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BHL62_09055	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BHL62_09060	COG0649	NAD binding
BHL62_09065	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BHL62_09070	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BHL62_09075	COG1034	ATP synthesis coupled electron transport
BHL62_09080	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BHL62_09110	COG1007	ATP synthesis coupled electron transport
BHL62_09120	COG0779	Required for maturation of 30S ribosomal subunits
BHL62_09125	COG0195	Participates in both transcription termination and antitermination
BHL62_09130	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BHL62_09145	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BHL62_09150	COG1185	polyribonucleotide nucleotidyltransferase activity
BHL62_09185	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BHL62_09195	COG2095	MarC family integral membrane protein
BHL62_09200	COG3039	Transposase
BHL62_09220	COG1611	Belongs to the LOG family
BHL62_09260	COG4969	Belongs to the N-Me-Phe pilin family
BHL62_09290	COG2963	transposase activity
BHL62_09310	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BHL62_09325	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BHL62_09380	COG0438	transferase activity, transferring glycosyl groups
BHL62_09385	COG0438	transferase activity, transferring glycosyl groups
BHL62_09395	COG0438	transferase activity, transferring glycosyl groups
BHL62_09440	COG3040	lipid binding
BHL62_09530	COG4191	Histidine kinase
BHL62_09530	COG0784	Response regulator, receiver
BHL62_09555	COG0552	protein localization to endoplasmic reticulum
BHL62_09565	COG3938	Belongs to the proline racemase family
BHL62_09570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BHL62_09585	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BHL62_09595	COG0006	proline dipeptidase activity
BHL62_09610	COG0531	amino acid
BHL62_09660	COG4206	TonB-dependent receptor
BHL62_09680	COG4206	TonB-dependent receptor
BHL62_09685	COG3328	transposase activity
BHL62_09755	COG0746	molybdenum cofactor guanylyltransferase activity
BHL62_09780	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BHL62_09780	COG1648	precorrin-2 dehydrogenase activity
BHL62_09815	COG3039	Transposase
BHL62_09830	COG3293	Transposase
BHL62_09845	COG3039	Transposase
BHL62_09875	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BHL62_09895	COG1054	Belongs to the UPF0176 family
BHL62_09920	COG1530	ribonuclease E activity
BHL62_09930	COG3064	Membrane
BHL62_09935	COG0428	transporter
BHL62_09940	COG0428	transporter
BHL62_10020	COG3039	Transposase
BHL62_10080	COG3039	Transposase
BHL62_10125	COG0631	protein serine/threonine phosphatase activity
BHL62_10130	COG0515	serine threonine protein kinase
BHL62_10160	COG1858	cytochrome C peroxidase
BHL62_10215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BHL62_10220	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BHL62_10235	COG3039	Transposase
BHL62_10275	COG2201	protein-glutamate methylesterase activity
BHL62_10300	COG0529	Catalyzes the synthesis of activated sulfate
BHL62_10300	COG2895	sulfate adenylyltransferase (ATP) activity
BHL62_10340	COG1981	membrane
BHL62_10365	COG1131	(ABC) transporter
BHL62_10370	COG4771	TonB-dependent receptor
BHL62_10385	COG0825	malonyl-CoA metabolic process
BHL62_10405	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BHL62_10410	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BHL62_10430	COG0750	zinc metalloprotease
BHL62_10435	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BHL62_10440	COG0575	Belongs to the CDS family
BHL62_10450	COG0233	cytoplasmic translational termination
BHL62_10465	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BHL62_10525	COG1393	Belongs to the ArsC family
BHL62_10540	COG0367	asparagine synthase
BHL62_10555	COG4774	siderophore transport
BHL62_10600	COG1566	PFAM secretion protein HlyD family protein
BHL62_10605	COG2814	Major facilitator Superfamily
BHL62_10620	COG3293	Transposase
BHL62_10650	COG3293	Transposase
BHL62_10675	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BHL62_10685	COG1960	acyl-CoA dehydrogenase activity
BHL62_10710	COG2914	Belongs to the UPF0125 (RnfH) family
BHL62_10720	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BHL62_10730	COG0497	DNA recombination
BHL62_10740	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BHL62_10745	COG0443	Heat shock 70 kDa protein
BHL62_10750	COG0484	heat shock protein binding
BHL62_10760	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BHL62_10765	COG0287	Prephenate dehydrogenase
BHL62_10765	COG1605	Chorismate mutase
BHL62_10780	COG0583	DNA-binding transcription factor activity
BHL62_10795	COG1132	(ABC) transporter
BHL62_10830	COG2850	peptidyl-arginine hydroxylation
BHL62_10875	COG3293	Transposase
BHL62_10920	COG1131	(ABC) transporter
BHL62_10925	COG1725	Transcriptional regulator
BHL62_10935	COG0386	Belongs to the glutathione peroxidase family
BHL62_10950	COG2900	Belongs to the SlyX family
BHL62_10965	COG1609	Transcriptional regulator
BHL62_10975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BHL62_10985	COG1410	methionine synthase
BHL62_10985	COG0646	methionine synthase
BHL62_10990	COG1410	methionine synthase
BHL62_10990	COG0646	methionine synthase
BHL62_10995	COG2226	methyltransferase
BHL62_11000	COG1960	acyl-CoA dehydrogenase activity
BHL62_11030	COG0557	exoribonuclease II activity
BHL62_11055	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BHL62_11065	COG3039	Transposase
BHL62_11075	COG3328	transposase activity
BHL62_11090	COG1278	Cold shock
BHL62_11160	COG3293	Transposase
BHL62_11215	COG3039	Transposase
BHL62_11235	COG3293	Transposase
BHL62_11250	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BHL62_11275	COG2166	iron-sulfur cluster assembly
BHL62_11290	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BHL62_11295	COG0137	argininosuccinate synthase activity
BHL62_11305	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BHL62_11310	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BHL62_11325	COG0165	Argininosuccinate lyase
BHL62_11375	COG1294	oxidase, subunit
BHL62_11400	COG4988	ABC transporter
BHL62_11405	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BHL62_11525	COG3209	COG3209 Rhs family protein
BHL62_11540	COG3328	transposase activity
BHL62_11545	COG3209	COG3209 Rhs family protein
BHL62_11565	COG0643	Histidine kinase
BHL62_11565	COG2198	Histidine kinase
BHL62_11565	COG0784	Response regulator, receiver
BHL62_11620	COG1684	flagellar biosynthetic protein fliR
BHL62_11640	COG3190	flagellar
BHL62_11690	COG1677	Flagellar hook-basal body complex protein FliE
BHL62_11730	COG1028	Short-chain dehydrogenase reductase Sdr
BHL62_11740	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BHL62_11760	COG2201	protein-glutamate methylesterase activity
BHL62_11790	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BHL62_11795	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BHL62_11830	COG4787	bacterial-type flagellum-dependent cell motility
BHL62_11840	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BHL62_11845	COG1558	bacterial-type flagellum-dependent cell motility
BHL62_11855	COG0835	chemotaxis
BHL62_11855	COG0784	Response regulator, receiver
BHL62_11875	COG5002	protein histidine kinase activity
BHL62_11885	COG4585	Histidine kinase
BHL62_11890	COG5001	Diguanylate cyclase
BHL62_11930	COG0542	response to heat
BHL62_11960	COG0492	ferredoxin-NADP+ reductase activity
BHL62_11965	COG1674	ftsk spoiiie
BHL62_11990	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BHL62_12010	COG0038	chloride channel
BHL62_12015	COG0183	Belongs to the thiolase family
BHL62_12020	COG1250	3-hydroxyacyl-CoA dehydrogenase
BHL62_12020	COG1024	Enoyl-CoA hydratase
BHL62_12035	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BHL62_12045	COG1426	Protein conserved in bacteria
BHL62_12055	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BHL62_12065	COG0303	'Molybdopterin
BHL62_12105	COG2826	transposase and inactivated derivatives, IS30 family
BHL62_12145	COG3039	Transposase
BHL62_12165	COG3039	Transposase
BHL62_12170	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BHL62_12195	COG0742	ribosomal rna small subunit methyltransferase
BHL62_12200	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BHL62_12215	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BHL62_12220	COG0405	Gamma-glutamyltransferase
BHL62_12235	COG3293	Transposase
BHL62_12315	COG0343	queuine tRNA-ribosyltransferase activity
BHL62_12320	COG1862	Preprotein translocase
BHL62_12330	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BHL62_12370	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BHL62_12380	COG0704	Plays a role in the regulation of phosphate uptake
BHL62_12395	COG0573	inorganic phosphate transmembrane transporter activity
BHL62_12400	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BHL62_12420	COG3293	Transposase
BHL62_12440	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BHL62_12450	COG1024	Enoyl-CoA hydratase
BHL62_12460	COG0494	nUDIX hydrolase
BHL62_12505	COG0116	Belongs to the methyltransferase superfamily
BHL62_12505	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BHL62_12530	COG0667	Aldo Keto reductase
BHL62_12540	COG2925	Exonuclease
BHL62_12565	COG0288	reversible hydration of carbon dioxide
BHL62_12595	COG0316	Belongs to the HesB IscA family
BHL62_12600	COG0360	Binds together with S18 to 16S ribosomal RNA
BHL62_12610	COG0359	binds to the 23S rRNA
BHL62_12620	COG3115	cell septum assembly
BHL62_12635	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
BHL62_12650	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BHL62_12685	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BHL62_12695	COG2986	histidine ammonia-lyase
BHL62_12700	COG1228	amidohydrolase
BHL62_12745	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BHL62_12755	COG0077	Prephenate dehydratase
BHL62_12755	COG1605	Chorismate mutase
BHL62_12760	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BHL62_12770	COG3328	transposase activity
BHL62_12850	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BHL62_12875	COG3293	Transposase
BHL62_12885	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BHL62_12890	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BHL62_12890	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BHL62_12895	COG0802	atpase or kinase
BHL62_12900	COG0860	N-Acetylmuramoyl-L-alanine amidase
BHL62_12905	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BHL62_12930	COG1028	Short-chain dehydrogenase reductase Sdr
BHL62_12950	COG2081	HI0933 family
BHL62_12955	COG4681	YaeQ
BHL62_12960	COG1671	Belongs to the UPF0178 family
BHL62_12970	COG0625	glutathione transferase activity
BHL62_12980	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BHL62_12990	COG0513	Belongs to the DEAD box helicase family
BHL62_12995	COG0488	(ABC) transporter
BHL62_13020	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BHL62_13025	COG0483	inositol monophosphate 1-phosphatase activity
BHL62_13040	COG3300	MHYT domain
BHL62_13040	COG5001	Diguanylate cyclase
BHL62_13045	COG1509	lysine 2,3-aminomutase activity
BHL62_13060	COG0402	S-adenosylhomocysteine deaminase activity
BHL62_13065	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BHL62_13095	COG4677	pectinesterase activity
BHL62_13125	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BHL62_13135	COG0531	amino acid
BHL62_13140	COG0531	amino acid
BHL62_13150	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BHL62_13155	COG0277	FAD linked oxidase domain protein
BHL62_13220	COG0436	Aminotransferase
BHL62_13245	COG1187	pseudouridine synthase activity
BHL62_13250	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BHL62_13255	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BHL62_13260	COG2350	Protein conserved in bacteria
BHL62_13290	COG1175	transmembrane transport
BHL62_13295	COG0395	ABC-type sugar transport system, permease component
BHL62_13320	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BHL62_13330	COG2957	Belongs to the agmatine deiminase family
BHL62_13345	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BHL62_13350	COG0539	negative regulation of cytoplasmic translation
BHL62_13355	COG0776	regulation of translation
BHL62_13365	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BHL62_13370	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BHL62_13380	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BHL62_13400	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BHL62_13415	COG3002	Belongs to the UPF0753 family
BHL62_13420	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BHL62_13425	COG0583	DNA-binding transcription factor activity
BHL62_13440	COG1028	Short-chain dehydrogenase reductase Sdr
BHL62_13455	COG0583	DNA-binding transcription factor activity
BHL62_13480	COG1914	H( )-stimulated, divalent metal cation uptake system
BHL62_13500	COG0668	transmembrane transport
BHL62_13510	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BHL62_13525	COG1028	Short-chain dehydrogenase reductase Sdr
BHL62_13530	COG1183	phosphatidylcholine synthase activity
BHL62_13540	COG3243	poly(R)-hydroxyalkanoic acid synthase
BHL62_13555	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BHL62_13555	COG0723	plastoquinol--plastocyanin reductase activity
BHL62_13565	COG2183	response to ionizing radiation
BHL62_13580	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BHL62_13595	COG0671	phosphoesterase, PA-phosphatase related
BHL62_13625	COG1794	racemase activity, acting on amino acids and derivatives
BHL62_13635	COG0697	spore germination
BHL62_13660	COG1012	belongs to the aldehyde dehydrogenase family
BHL62_13705	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BHL62_13720	COG0124	histidyl-tRNA synthetase
BHL62_13745	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BHL62_13760	COG0131	Imidazoleglycerol-phosphate dehydratase
BHL62_13760	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BHL62_13770	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BHL62_13780	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BHL62_13780	COG0140	phosphoribosyl-ATP diphosphatase activity
BHL62_13890	COG0653	protein targeting
BHL62_13965	COG2201	protein-glutamate methylesterase activity
BHL62_13975	COG2801	Transposase and inactivated derivatives
BHL62_14020	COG0322	excinuclease ABC activity
BHL62_14030	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BHL62_14040	COG1663	tetraacyldisaccharide 4'-kinase activity
BHL62_14055	COG0811	peptide transport
BHL62_14085	COG4591	ABC-type transport system involved in lipoprotein release permease component
BHL62_14100	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BHL62_14115	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BHL62_14130	COG0354	folic acid binding
BHL62_14145	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BHL62_14155	COG0363	glucosamine-6-phosphate deaminase activity
BHL62_14160	COG0129	dihydroxy-acid dehydratase activity
BHL62_14165	COG0800	Aldolase
BHL62_14195	COG5002	protein histidine kinase activity
BHL62_14195	COG2205	protein histidine kinase activity
BHL62_14195	COG0784	Response regulator, receiver
BHL62_14210	COG3293	Transposase
BHL62_14250	COG3039	Transposase
BHL62_14260	COG3328	transposase activity
BHL62_14300	COG0386	Belongs to the glutathione peroxidase family
BHL62_14385	COG4251	negative regulation of phosphorylation
BHL62_14385	COG5001	Diguanylate cyclase
BHL62_14385	COG2203	Gaf domain
BHL62_14385	COG3706	GGDEF domain
BHL62_14405	COG1472	Belongs to the glycosyl hydrolase 3 family
BHL62_14460	COG1469	GTP cyclohydrolase I activity
BHL62_14465	COG0860	N-Acetylmuramoyl-L-alanine amidase
BHL62_14515	COG3039	Transposase
BHL62_14550	COG4566	intracellular signal transduction
BHL62_14610	COG2969	positive regulation of protein catabolic process
BHL62_14615	COG0625	glutathione transferase activity
BHL62_14620	COG2857	Cytochrome c1
BHL62_14625	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BHL62_14630	COG0723	plastoquinol--plastocyanin reductase activity
BHL62_14635	COG0741	lytic transglycosylase activity
BHL62_14660	COG1702	phosphate starvation-inducible protein PhoH
BHL62_14680	COG4535	Mg2 and Co2 transporter CorC
BHL62_14695	COG1012	belongs to the aldehyde dehydrogenase family
BHL62_14705	COG1177	transmembrane transport
BHL62_14710	COG1176	ABC-type spermidine putrescine transport system, permease component I
BHL62_14715	COG3842	ATPase activity
BHL62_14760	COG0174	glutamine synthetase
BHL62_14765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BHL62_14775	COG0477	Major facilitator Superfamily
BHL62_14785	COG0243	molybdopterin cofactor binding
BHL62_14795	COG2223	nitrite transmembrane transporter activity
BHL62_14805	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BHL62_14810	COG1121	(ABC) transporter
BHL62_14820	COG2733	membrane
BHL62_14825	COG0784	Response regulator, receiver
BHL62_14825	COG2205	protein histidine kinase activity
BHL62_14825	COG5002	protein histidine kinase activity
BHL62_14840	COG3039	Transposase
BHL62_14850	COG2902	Dehydrogenase
BHL62_14860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BHL62_14865	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BHL62_14880	COG3385	transposase activity
BHL62_14885	COG1609	Transcriptional regulator
BHL62_14890	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BHL62_14890	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BHL62_14895	COG1105	Belongs to the carbohydrate kinase PfkB family
BHL62_14900	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BHL62_14900	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BHL62_14915	COG3039	Transposase
BHL62_14920	COG3328	transposase activity
BHL62_14950	COG3039	Transposase
BHL62_15045	COG4771	TonB-dependent receptor
BHL62_15055	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BHL62_15075	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BHL62_15080	COG1360	Flagellar Motor Protein
BHL62_15090	COG0835	chemotaxis
BHL62_15100	COG0745	RESPONSE REGULATOR receiver
BHL62_15120	COG0840	transmembrane signaling receptor activity
BHL62_15130	COG0840	transmembrane signaling receptor activity
BHL62_15140	COG3293	Transposase
BHL62_15150	COG0840	transmembrane signaling receptor activity
BHL62_15160	COG0840	transmembrane signaling receptor activity
BHL62_15170	COG0840	transmembrane signaling receptor activity
BHL62_15175	COG0840	transmembrane signaling receptor activity
BHL62_15190	COG0835	chemotaxis
BHL62_15215	COG0840	transmembrane signaling receptor activity
BHL62_15245	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BHL62_15275	COG0318	PFAM AMP-dependent synthetase and ligase
BHL62_15280	COG1024	Enoyl-CoA hydratase
BHL62_15285	COG2205	protein histidine kinase activity
BHL62_15285	COG0784	Response regulator, receiver
BHL62_15285	COG2198	Histidine kinase
BHL62_15380	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BHL62_15390	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BHL62_15395	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BHL62_15405	COG0505	Belongs to the CarA family
BHL62_15410	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BHL62_15420	COG3293	Transposase
BHL62_15425	COG2258	MOSC domain
BHL62_15430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BHL62_15480	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BHL62_15500	COG0477	Major facilitator Superfamily
BHL62_15510	COG1070	Carbohydrate kinase
BHL62_15520	COG1501	Belongs to the glycosyl hydrolase 31 family
BHL62_15535	COG0800	Aldolase
BHL62_15540	COG4948	Mandelate Racemase Muconate Lactonizing
BHL62_15550	COG3734	2-keto-3-deoxy-galactonokinase
BHL62_15555	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BHL62_15565	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BHL62_15580	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BHL62_15585	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BHL62_15595	COG0351	phosphomethylpyrimidine kinase
BHL62_15625	COG0583	DNA-binding transcription factor activity
BHL62_15630	COG1741	Belongs to the pirin family
BHL62_15650	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BHL62_15655	COG0305	Participates in initiation and elongation during chromosome replication
BHL62_15675	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BHL62_15680	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BHL62_15685	COG2137	regulation of response to DNA damage stimulus
BHL62_15690	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BHL62_15705	COG1546	Belongs to the CinA family
BHL62_15710	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BHL62_15725	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BHL62_15735	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BHL62_15740	COG1534	Rna-binding protein
BHL62_15755	COG1238	metal cluster binding
BHL62_15760	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BHL62_15765	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BHL62_15770	COG2840	Smr protein MutS2
BHL62_15780	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BHL62_15790	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BHL62_15795	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BHL62_15800	COG0148	phosphopyruvate hydratase activity
BHL62_15810	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BHL62_15815	COG0504	CTP synthase activity
BHL62_15835	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BHL62_15840	COG0306	phosphate transporter
BHL62_15855	COG1253	flavin adenine dinucleotide binding
BHL62_15870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BHL62_15900	COG0477	Major facilitator Superfamily
BHL62_15915	COG3293	Transposase
BHL62_15920	COG1132	(ABC) transporter
BHL62_15925	COG1136	(ABC) transporter
BHL62_15940	COG0438	transferase activity, transferring glycosyl groups
BHL62_15950	COG2264	protein methyltransferase activity
BHL62_15980	COG2244	polysaccharide biosynthetic process
BHL62_16030	COG1595	DNA-templated transcription, initiation
BHL62_16045	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BHL62_16065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BHL62_16095	COG2201	protein-glutamate methylesterase activity
BHL62_16110	COG0583	DNA-binding transcription factor activity
BHL62_16120	COG3039	Transposase
BHL62_16160	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BHL62_16175	COG2040	homocysteine
BHL62_16180	COG0833	amino acid
BHL62_16200	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BHL62_16200	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BHL62_16210	COG2878	Part of a membrane complex involved in electron transport
BHL62_16230	COG1595	DNA-templated transcription, initiation
BHL62_16255	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BHL62_16270	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BHL62_16275	COG0251	oxidation-reduction process
BHL62_16285	COG0392	lysyltransferase activity
BHL62_16285	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BHL62_16335	COG2814	Major facilitator Superfamily
BHL62_16340	COG1902	pentaerythritol trinitrate reductase activity
BHL62_16355	COG2824	Alkylphosphonate utilization operon protein PhnA
BHL62_16370	COG1047	Peptidyl-prolyl cis-trans
BHL62_16430	COG3293	Transposase
BHL62_16440	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BHL62_16455	COG1451	nucleotide metabolic process
BHL62_16485	COG0183	Belongs to the thiolase family
BHL62_16520	COG1793	dna ligase
BHL62_16520	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BHL62_16530	COG1793	dna ligase
BHL62_16535	COG1201	RNA secondary structure unwinding
BHL62_16555	COG1278	Cold shock
BHL62_16560	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BHL62_16565	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BHL62_16575	COG3046	protein related to deoxyribodipyrimidine photolyase
BHL62_16580	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
BHL62_16585	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BHL62_16605	COG2954	triphosphatase activity
BHL62_16620	COG1381	Involved in DNA repair and RecF pathway recombination
BHL62_16650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BHL62_16665	COG1024	Enoyl-CoA hydratase
BHL62_16665	COG1250	3-hydroxyacyl-CoA dehydrogenase
BHL62_16685	COG1024	Enoyl-CoA hydratase
BHL62_16690	COG1960	acyl-CoA dehydrogenase activity
BHL62_16775	COG2353	YceI-like domain
BHL62_16785	COG2353	YceI-like domain
BHL62_16800	COG1760	l-serine dehydratase
BHL62_16810	COG0626	cystathionine gamma-synthase activity
BHL62_16815	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BHL62_16820	COG0739	heme binding
BHL62_16830	COG1272	protein, Hemolysin III
BHL62_16850	COG0516	GMP reductase activity
BHL62_16850	COG0517	IMP dehydrogenase activity
BHL62_16855	COG0463	Glycosyl transferase, family 2
BHL62_16865	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BHL62_16875	COG4771	TonB-dependent receptor
BHL62_16880	COG1309	transcriptional regulator
BHL62_16890	COG1960	acyl-CoA dehydrogenase activity
BHL62_16930	COG0509	glycine decarboxylation via glycine cleavage system
BHL62_16945	COG0330	HflC and HflK could
BHL62_16960	COG3956	TIGRFAM MazG family protein
BHL62_16970	COG0494	nUDIX hydrolase
BHL62_16980	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BHL62_16985	COG0837	glucose binding
BHL62_17000	COG1388	LysM domain
BHL62_17000	COG3858	chitin binding
BHL62_17010	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BHL62_17020	COG1472	Belongs to the glycosyl hydrolase 3 family
BHL62_17075	COG3328	transposase activity
BHL62_17085	COG3537	Alpha-1,2-mannosidase
BHL62_17140	COG1446	asparaginase
BHL62_17165	COG3293	Transposase
BHL62_17205	COG0784	Response regulator, receiver
BHL62_17205	COG0643	Histidine kinase
BHL62_17205	COG2198	Histidine kinase
BHL62_17210	COG0840	transmembrane signaling receptor activity
BHL62_17215	COG0835	chemotaxis
BHL62_17230	COG0189	ligase activity
BHL62_17240	COG1397	ADP-ribosylglycohydrolase
BHL62_17250	COG1199	ATP-dependent helicase activity
BHL62_17260	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BHL62_17265	COG1215	transferase activity, transferring glycosyl groups
BHL62_17275	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BHL62_17295	COG0535	radical SAM domain protein
BHL62_17300	COG0535	radical SAM domain protein
BHL62_17315	COG0837	glucose binding
BHL62_17340	COG1643	Atp-dependent helicase
BHL62_17345	COG0783	Belongs to the Dps family
BHL62_17350	COG3039	Transposase
BHL62_17360	COG0514	ATP-dependent DNA helicase (RecQ)
BHL62_17395	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BHL62_17440	COG1187	pseudouridine synthase activity
BHL62_17445	COG0602	queuosine metabolic process
BHL62_17455	COG2885	chlorophyll binding
BHL62_17470	COG0848	biopolymer transport protein
BHL62_17480	COG0824	Thioesterase
BHL62_17485	COG2255	four-way junction helicase activity
BHL62_17495	COG0632	four-way junction helicase activity
BHL62_17615	COG2963	transposase activity
BHL62_17645	COG3209	COG3209 Rhs family protein
BHL62_17665	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BHL62_17670	COG1845	cytochrome c oxidase, subunit III
BHL62_17675	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BHL62_17690	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BHL62_17695	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BHL62_17705	COG0196	riboflavin kinase activity
BHL62_17710	COG0728	peptidoglycan biosynthetic process
BHL62_17715	COG0268	Binds directly to 16S ribosomal RNA
BHL62_17720	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BHL62_17725	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BHL62_17735	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BHL62_17740	COG0824	Thioesterase
BHL62_17755	COG1946	Acyl-CoA thioesterase
BHL62_17780	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BHL62_17825	COG1877	trehalose-phosphatase activity
BHL62_17830	COG3387	PFAM Glycoside hydrolase 15-related
BHL62_17855	COG0564	pseudouridine synthase activity
BHL62_17860	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BHL62_17865	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BHL62_17865	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BHL62_17875	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BHL62_17880	COG0045	succinate-CoA ligase (ADP-forming) activity
BHL62_17920	COG2194	sulfuric ester hydrolase activity
BHL62_17925	COG4969	Belongs to the N-Me-Phe pilin family
BHL62_17935	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BHL62_17955	COG3328	transposase activity
BHL62_17970	COG3209	COG3209 Rhs family protein
BHL62_17975	COG3039	Transposase
BHL62_17995	COG3293	Transposase
BHL62_18005	COG1132	(ABC) transporter
BHL62_18035	COG0745	RESPONSE REGULATOR receiver
BHL62_18040	COG5000	phosphorelay sensor kinase activity
BHL62_18040	COG5002	protein histidine kinase activity
BHL62_18045	COG0475	glutathione-regulated potassium exporter activity
BHL62_18055	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BHL62_18075	COG1187	pseudouridine synthase activity
BHL62_18080	COG5002	protein histidine kinase activity
BHL62_18080	COG5001	Diguanylate cyclase
BHL62_18210	COG0415	Belongs to the DNA photolyase family
BHL62_18215	COG0305	Participates in initiation and elongation during chromosome replication
BHL62_18225	COG0367	asparagine synthase
BHL62_18240	COG1960	acyl-CoA dehydrogenase activity
BHL62_18255	COG0084	hydrolase, TatD family'
BHL62_18260	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BHL62_18315	COG0735	belongs to the Fur family
BHL62_18320	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BHL62_18380	COG3039	Transposase
BHL62_18390	COG3039	Transposase
BHL62_18410	COG2205	protein histidine kinase activity
BHL62_18420	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BHL62_18430	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BHL62_18440	COG0643	Histidine kinase
BHL62_18440	COG2198	Histidine kinase
BHL62_18450	COG0840	transmembrane signaling receptor activity
BHL62_18455	COG0835	chemotaxis
BHL62_18460	COG2199	diguanylate cyclase activity
BHL62_18460	COG2202	Pas domain
BHL62_18460	COG2200	EAL domain
BHL62_18465	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BHL62_18475	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BHL62_18480	COG3590	peptidase
BHL62_18500	COG1515	deoxyribonuclease V activity
BHL62_18510	COG1741	Belongs to the pirin family
BHL62_18630	COG2963	transposase activity
BHL62_18660	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BHL62_18675	COG2197	response regulator
BHL62_18680	COG4585	Histidine kinase
BHL62_18705	COG2894	cell division
BHL62_18710	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BHL62_18720	COG0642	Histidine kinase
BHL62_18725	COG0745	RESPONSE REGULATOR receiver
BHL62_18730	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BHL62_18740	COG2194	sulfuric ester hydrolase activity
BHL62_18770	COG3551	Protein conserved in bacteria
BHL62_18830	COG2963	transposase activity
BHL62_18840	COG3293	Transposase
BHL62_18855	COG0203	ribosomal protein L17
BHL62_18865	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BHL62_18870	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BHL62_18880	COG0201	protein transport
BHL62_18890	COG1841	ribosomal large subunit assembly
BHL62_18920	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BHL62_18930	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BHL62_18935	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BHL62_18940	COG0255	Belongs to the universal ribosomal protein uL29 family
BHL62_18945	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BHL62_18970	COG0089	rRNA binding
BHL62_18975	COG0088	Forms part of the polypeptide exit tunnel
BHL62_18980	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BHL62_18985	COG0051	transcription antitermination factor activity, RNA binding
BHL62_19005	COG0049	tRNA binding
BHL62_19010	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BHL62_19015	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BHL62_19020	COG0085	RNA polymerase activity
BHL62_19025	COG0222	ribosome binding
BHL62_19030	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BHL62_19040	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BHL62_19050	COG0250	Participates in transcription elongation, termination and antitermination
BHL62_19055	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BHL62_19085	COG0012	GTP binding
BHL62_19090	COG0193	aminoacyl-tRNA hydrolase activity
BHL62_19100	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BHL62_19115	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BHL62_19130	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BHL62_19140	COG0521	Mo-molybdopterin cofactor biosynthetic process
BHL62_19160	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BHL62_19165	COG1295	ribonuclease BN
BHL62_19195	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BHL62_19205	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BHL62_19235	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BHL62_19260	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BHL62_19275	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BHL62_19275	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BHL62_19320	COG2890	protein-(glutamine-N5) methyltransferase activity
BHL62_19330	COG3634	alkyl hydroperoxide reductase activity
BHL62_19335	COG0583	DNA-binding transcription factor activity
BHL62_19340	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BHL62_19345	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BHL62_19385	COG2197	response regulator
BHL62_19425	COG2826	transposase and inactivated derivatives, IS30 family
BHL62_19435	COG3293	Transposase
BHL62_19490	COG3386	PFAM SMP-30 Gluconolaconase
BHL62_19510	COG1024	Enoyl-CoA hydratase
BHL62_19520	COG0318	PFAM AMP-dependent synthetase and ligase
BHL62_19525	COG0583	DNA-binding transcription factor activity
BHL62_19540	COG2186	Transcriptional regulator
BHL62_19565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BHL62_19570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BHL62_19580	COG2096	Adenosyltransferase
BHL62_19585	COG0123	including yeast histone deacetylase and acetoin utilization protein
BHL62_19600	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BHL62_19610	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BHL62_19615	COG2967	ApaG domain
BHL62_19640	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BHL62_19660	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BHL62_19685	COG0642	Histidine kinase
BHL62_19700	COG4181	ATPase activity
BHL62_19710	COG2175	clavaminate synthase activity
BHL62_19760	COG0667	Aldo Keto reductase
BHL62_19770	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BHL62_19775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BHL62_19790	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BHL62_19805	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BHL62_19840	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BHL62_19845	COG2226	methyltransferase
BHL62_19900	COG0604	alcohol dehydrogenase
BHL62_19900	COG1028	Short-chain dehydrogenase reductase Sdr
BHL62_19900	COG3321	synthase
BHL62_19915	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BHL62_19930	COG0494	nUDIX hydrolase
BHL62_19945	COG4942	peptidase
BHL62_19945	COG1388	LysM domain
BHL62_19955	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BHL62_19970	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BHL62_19975	COG1181	Belongs to the D-alanine--D-alanine ligase family
BHL62_19980	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BHL62_20000	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BHL62_20015	COG3116	cell division
BHL62_20020	COG0275	rRNA processing
BHL62_20055	COG0792	nuclease activity
BHL62_20060	COG1988	membrane-bound metal-dependent
BHL62_20065	COG0277	FAD linked oxidase domain protein
BHL62_20070	COG0745	RESPONSE REGULATOR receiver
BHL62_20075	COG2205	protein histidine kinase activity
BHL62_20085	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BHL62_20090	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BHL62_20125	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BHL62_20130	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BHL62_20135	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BHL62_20155	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BHL62_20155	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BHL62_20175	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BHL62_20195	COG0488	(ABC) transporter
BHL62_20250	COG2205	protein histidine kinase activity
BHL62_20290	COG2205	protein histidine kinase activity
BHL62_20305	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BHL62_20350	COG3039	Transposase
BHL62_20415	COG3293	Transposase
BHL62_20435	COG1649	PFAM Uncharacterised BCR, COG1649
BHL62_20435	COG0726	polysaccharide deacetylase
BHL62_20440	COG1215	transferase activity, transferring glycosyl groups
BHL62_20450	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BHL62_20455	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BHL62_20460	COG1609	Transcriptional regulator
BHL62_20470	COG2188	Transcriptional regulator
BHL62_20485	COG3250	beta-galactosidase activity
BHL62_20535	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BHL62_20540	COG4191	Histidine kinase
BHL62_20545	COG0784	Response regulator, receiver
BHL62_20550	COG4251	negative regulation of phosphorylation
BHL62_20555	COG2823	Periplasmic or secreted lipoprotein
BHL62_20560	COG0673	inositol 2-dehydrogenase activity
BHL62_20565	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BHL62_20600	COG1051	belongs to the nudix hydrolase family
BHL62_20600	COG1056	cytidyltransferase-related domain
BHL62_20645	COG2921	Belongs to the UPF0250 family
BHL62_20655	COG1686	Belongs to the peptidase S11 family
BHL62_20665	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BHL62_20670	COG2951	lytic endotransglycosylase activity
BHL62_20725	COG0772	Belongs to the SEDS family
BHL62_20740	COG1792	Involved in formation and maintenance of cell shape
BHL62_20745	COG1077	Cell shape determining protein MreB Mrl
BHL62_20750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BHL62_20795	COG2199	diguanylate cyclase activity
BHL62_20800	COG0308	aminopeptidase N
BHL62_20835	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BHL62_20865	COG0436	Aminotransferase
BHL62_20880	COG1505	serine-type exopeptidase activity
BHL62_20910	COG0181	hydroxymethylbilane synthase activity
BHL62_20920	COG3275	phosphorelay sensor kinase activity
BHL62_20960	COG0659	secondary active sulfate transmembrane transporter activity
BHL62_20965	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BHL62_20965	COG5297	Belongs to the glycosyl hydrolase family 6
BHL62_21005	COG3293	Transposase
BHL62_21045	COG0598	Magnesium transport protein CorA
BHL62_21055	COG1113	amino acid transport
BHL62_21065	COG5297	Belongs to the glycosyl hydrolase family 6
BHL62_21070	COG4305	rare lipoprotein A
BHL62_21075	COG0697	spore germination
BHL62_21135	COG4221	oxidoreductase activity
BHL62_21170	COG0456	acetyltransferase
BHL62_21180	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BHL62_21210	COG3227	Zinc metalloprotease (Elastase)
BHL62_21225	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BHL62_21225	COG2111	Na H antiporter
BHL62_21230	COG1006	Multisubunit Na H antiporter MnhC subunit
BHL62_21235	COG0651	ATP synthesis coupled electron transport
BHL62_21245	COG2212	antiporter activity
BHL62_21250	COG1320	monovalent cation:proton antiporter activity
BHL62_21280	COG3104	oligopeptide transport
BHL62_21285	COG3483	tryptophan 2,3-dioxygenase activity
BHL62_21295	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BHL62_21325	COG3293	Transposase
BHL62_21335	COG0183	Belongs to the thiolase family
BHL62_21410	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
BHL62_21415	COG3023	N-Acetylmuramoyl-L-alanine amidase
BHL62_21425	COG4948	Mandelate Racemase Muconate Lactonizing
BHL62_21455	COG0531	amino acid
BHL62_21465	COG3293	Transposase
BHL62_21485	COG4682	membrane
BHL62_21490	COG2133	pyrroloquinoline quinone binding
BHL62_21575	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BHL62_21580	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BHL62_21590	COG1610	YqeY-like protein
BHL62_21600	COG1295	ribonuclease BN
BHL62_21605	COG0358	DNA primase activity
BHL62_21665	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
BHL62_21675	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BHL62_21690	COG2963	transposase activity
BHL62_21735	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BHL62_21740	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BHL62_21745	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
BHL62_21755	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BHL62_21760	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BHL62_21775	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BHL62_21850	COG3328	transposase activity
BHL62_21860	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BHL62_21860	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BHL62_21870	COG1473	amidohydrolase
BHL62_21875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BHL62_21880	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BHL62_21895	COG5383	Protein conserved in bacteria
BHL62_21925	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BHL62_21930	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BHL62_21945	COG0028	Belongs to the TPP enzyme family
BHL62_21950	COG4191	Histidine kinase
BHL62_21975	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BHL62_21990	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BHL62_21995	COG3177	Filamentation induced by cAMP protein fic
BHL62_22010	COG0596	Alpha beta hydrolase
BHL62_22015	COG0727	PFAM Uncharacterised protein family (UPF0153)
BHL62_22020	COG0318	PFAM AMP-dependent synthetase and ligase
BHL62_22025	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BHL62_22040	COG3039	Transposase
BHL62_22060	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BHL62_22070	COG0129	dihydroxy-acid dehydratase activity
BHL62_22100	COG3039	Transposase
BHL62_22110	COG0408	coproporphyrinogen oxidase activity
BHL62_22140	COG2963	transposase activity
BHL62_22170	COG3039	Transposase
BHL62_22180	COG2201	protein-glutamate methylesterase activity
BHL62_22230	COG2353	YceI-like domain
BHL62_22265	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BHL62_22280	COG3386	PFAM SMP-30 Gluconolaconase
BHL62_22325	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BHL62_22340	COG4771	TonB-dependent receptor
BHL62_22350	COG0459	protein refolding
BHL62_22375	COG1252	NADH dehydrogenase
BHL62_22385	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BHL62_22390	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BHL62_22395	COG2201	protein-glutamate methylesterase activity
BHL62_22400	COG2177	Part of the ABC transporter FtsEX involved in
BHL62_22405	COG2884	Cell division ATP-binding protein ftsE
BHL62_22415	COG3118	belongs to the thioredoxin family
BHL62_22420	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BHL62_22435	COG2963	transposase activity
BHL62_22445	COG0729	surface antigen
BHL62_22450	COG2911	Protein conserved in bacteria
BHL62_22485	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BHL62_22500	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BHL62_22560	COG1733	regulation of RNA biosynthetic process
BHL62_22565	COG0702	epimerase
BHL62_22595	COG0583	DNA-binding transcription factor activity
BHL62_22600	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BHL62_22615	COG2205	protein histidine kinase activity
BHL62_22620	COG2205	protein histidine kinase activity
BHL62_22625	COG0745	RESPONSE REGULATOR receiver
BHL62_22655	COG1902	pentaerythritol trinitrate reductase activity
BHL62_22660	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BHL62_22670	COG2814	Major facilitator Superfamily
BHL62_22675	COG0583	DNA-binding transcription factor activity
BHL62_22695	COG0084	hydrolase, TatD family'
BHL62_22770	COG3039	Transposase
BHL62_22810	COG3328	transposase activity
BHL62_22845	COG2826	transposase and inactivated derivatives, IS30 family
BHL62_22855	COG4770	biotin carboxylase activity
BHL62_22860	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BHL62_22865	COG1960	acyl-CoA dehydrogenase activity
BHL62_22920	COG0523	cobalamin synthesis protein
BHL62_22940	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BHL62_22955	COG4771	TonB-dependent receptor
BHL62_22960	COG0457	Tetratricopeptide repeat
BHL62_22970	COG0752	glycyl-tRNA synthetase alpha subunit
BHL62_22975	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BHL62_23010	COG0519	Catalyzes the synthesis of GMP from XMP
BHL62_23010	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BHL62_23020	COG0805	protein transport
BHL62_23030	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BHL62_23040	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BHL62_23070	COG2974	May be involved in recombination
BHL62_23075	COG0037	tRNA processing
BHL62_23095	COG3661	Belongs to the glycosyl hydrolase 67 family
BHL62_23105	COG4948	Mandelate Racemase Muconate Lactonizing
BHL62_23115	COG1472	Belongs to the glycosyl hydrolase 3 family
BHL62_23120	COG0246	Mannitol dehydrogenase
BHL62_23145	COG3693	PFAM glycoside hydrolase, family 10
BHL62_23170	COG2211	Major facilitator Superfamily
BHL62_23205	COG3293	Transposase
BHL62_23225	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BHL62_23270	COG1846	Transcriptional regulator
BHL62_23275	COG1764	response to oxidative stress
BHL62_23345	COG3549	Plasmid maintenance system killer
BHL62_23355	COG1074	ATP-dependent DNA helicase activity
BHL62_23360	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BHL62_23400	COG2032	superoxide dismutase activity
BHL62_23405	COG2032	superoxide dismutase activity
BHL62_23410	COG2204	response regulator
BHL62_23415	COG3852	Histidine kinase
BHL62_23420	COG0004	ammonium transporteR
BHL62_23425	COG0347	Belongs to the P(II) protein family
BHL62_23430	COG0174	glutamine synthetase
BHL62_23435	COG1968	undecaprenyl-diphosphatase activity
BHL62_23480	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BHL62_23490	COG2062	phosphohistidine phosphatase, SixA
BHL62_23495	COG0489	protein tyrosine kinase activity
BHL62_23515	COG1396	sequence-specific DNA binding
BHL62_23520	COG3550	peptidyl-serine autophosphorylation
BHL62_23525	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
BHL62_23530	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BHL62_23555	COG1125	glycine betaine transport
BHL62_23555	COG0517	IMP dehydrogenase activity
BHL62_23570	COG1119	ATPase activity
BHL62_23580	COG1752	Esterase of the alpha-beta hydrolase superfamily
BHL62_23630	COG3328	transposase activity
BHL62_23640	COG2963	transposase activity
BHL62_23655	COG0604	alcohol dehydrogenase
BHL62_23655	COG1028	Short-chain dehydrogenase reductase Sdr
BHL62_23655	COG3321	synthase
BHL62_23660	COG2937	Belongs to the GPAT DAPAT family
BHL62_23695	COG0284	orotidine-5'-phosphate decarboxylase activity
BHL62_23700	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BHL62_23705	COG3132	Protein of unknown function, DUF480
BHL62_23720	COG0210	DNA helicase
BHL62_23735	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
BHL62_23770	COG1028	Short-chain dehydrogenase reductase Sdr
BHL62_23795	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BHL62_23855	COG3293	Transposase
BHL62_23885	COG1166	arginine decarboxylase activity
BHL62_23890	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BHL62_23905	COG3328	transposase activity
BHL62_23970	COG0606	chelatase, subunit chli
BHL62_23990	COG3039	Transposase
BHL62_24040	COG1127	ABC transporter
BHL62_24045	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BHL62_24050	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BHL62_24065	COG2853	Lipoprotein
BHL62_24080	COG3293	Transposase
BHL62_24095	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BHL62_24125	COG2963	transposase activity
BHL62_24190	COG0676	glucose-6-phosphate 1-epimerase activity
BHL62_24215	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BHL62_24225	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BHL62_24235	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BHL62_24245	COG1064	alcohol dehydrogenase
BHL62_24295	COG1522	sequence-specific DNA binding
BHL62_24300	COG3186	Phenylalanine-4-hydroxylase
BHL62_24315	COG2755	lipolytic protein G-D-S-L family
BHL62_24325	COG2801	Transposase and inactivated derivatives
BHL62_24345	COG0656	L-ascorbic acid biosynthetic process
BHL62_24350	COG2130	NADP-dependent
BHL62_24355	COG0667	Aldo Keto reductase
BHL62_24365	COG1187	pseudouridine synthase activity
BHL62_24380	COG1643	Atp-dependent helicase
BHL62_24385	COG4807	Protein conserved in bacteria
BHL62_24390	COG4948	Mandelate Racemase Muconate Lactonizing
BHL62_24400	COG0179	Fumarylacetoacetate (FAA) hydrolase
BHL62_24405	COG1028	Short-chain dehydrogenase reductase Sdr
BHL62_24425	COG3507	Belongs to the glycosyl hydrolase 43 family
BHL62_24470	COG3162	membrane
BHL62_24475	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BHL62_24490	COG0708	Exodeoxyribonuclease III
BHL62_24505	COG2091	lysine biosynthetic process via aminoadipic acid
BHL62_24515	COG3540	Alkaline phosphatase
BHL62_24520	COG0357	Ribosomal RNA small subunit methyltransferase G
BHL62_24545	COG2159	amidohydrolase
BHL62_24560	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BHL62_24565	COG0583	DNA-binding transcription factor activity
BHL62_24570	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BHL62_24585	COG0210	DNA helicase
BHL62_24600	COG0531	amino acid
BHL62_24625	COG0386	Belongs to the glutathione peroxidase family
BHL62_24680	COG0793	Belongs to the peptidase S41A family
BHL62_24685	COG4942	peptidase
BHL62_24695	COG2234	aminopeptidase activity
BHL62_24745	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BHL62_24750	COG0302	gtp cyclohydrolase
BHL62_24770	COG0477	Major facilitator Superfamily
BHL62_24785	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BHL62_24860	COG1929	Belongs to the glycerate kinase type-1 family
BHL62_24865	COG2271	Major facilitator Superfamily
BHL62_24880	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BHL62_24890	COG0861	Integral membrane protein TerC family
BHL62_24900	COG0584	glycerophosphoryl diester phosphodiesterase
BHL62_24910	COG0671	phosphoesterase, PA-phosphatase related
BHL62_24915	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BHL62_24920	COG0726	polysaccharide deacetylase