locus-tag	class	description
IXO1088_000010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IXO1088_000030	COG0187	DNA topoisomerase II activity
IXO1088_000040	COG0501	Belongs to the peptidase M48B family
IXO1088_000070	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IXO1088_000080	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IXO1088_000090	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
IXO1088_000100	COG4772	TonB-dependent receptor
IXO1088_000115	COG3039	Transposase
IXO1088_000120	COG1304	FMN binding
IXO1088_000140	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IXO1088_000150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IXO1088_000245	COG2826	transposase and inactivated derivatives, IS30 family
IXO1088_000270	COG3039	Transposase
IXO1088_000280	COG1090	epimerase
IXO1088_000290	COG0642	Histidine kinase
IXO1088_000300	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IXO1088_000405	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IXO1088_000485	COG1511	domain protein
IXO1088_000485	COG3264	Mechanosensitive ion channel
IXO1088_000500	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IXO1088_000510	COG2354	Protein conserved in bacteria
IXO1088_000525	COG0297	glycogen (starch) synthase activity
IXO1088_000535	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IXO1088_000560	COG0702	epimerase
IXO1088_000575	COG1858	cytochrome C peroxidase
IXO1088_000655	COG0513	Belongs to the DEAD box helicase family
IXO1088_000665	COG3039	Transposase
IXO1088_000715	COG1272	protein, Hemolysin III
IXO1088_000720	COG1111	helicase
IXO1088_000720	COG1205	dead DEAH box helicase
IXO1088_000780	COG0067	glutamate synthase
IXO1088_000780	COG0069	glutamate synthase activity
IXO1088_000780	COG0070	glutamate synthase
IXO1088_000785	COG0493	'glutamate synthase
IXO1088_000830	COG1609	Transcriptional regulator
IXO1088_000865	COG0366	Alpha amylase catalytic
IXO1088_000870	COG0366	Alpha amylase catalytic
IXO1088_000910	COG3039	Transposase
IXO1088_000940	COG0606	chelatase, subunit chli
IXO1088_000990	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IXO1088_000995	COG1166	arginine decarboxylase activity
IXO1088_001005	COG3501	Rhs element vgr protein
IXO1088_001070	COG1028	Short-chain dehydrogenase reductase Sdr
IXO1088_001095	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
IXO1088_001110	COG0210	DNA helicase
IXO1088_001125	COG3132	Protein of unknown function, DUF480
IXO1088_001130	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
IXO1088_001135	COG0284	orotidine-5'-phosphate decarboxylase activity
IXO1088_001210	COG1752	Esterase of the alpha-beta hydrolase superfamily
IXO1088_001220	COG1119	ATPase activity
IXO1088_001235	COG0517	IMP dehydrogenase activity
IXO1088_001235	COG1125	glycine betaine transport
IXO1088_001250	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IXO1088_001255	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
IXO1088_001260	COG3550	peptidyl-serine autophosphorylation
IXO1088_001265	COG1396	sequence-specific DNA binding
IXO1088_001285	COG0489	protein tyrosine kinase activity
IXO1088_001290	COG2062	phosphohistidine phosphatase, SixA
IXO1088_001300	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IXO1088_001345	COG1968	undecaprenyl-diphosphatase activity
IXO1088_001350	COG0174	glutamine synthetase
IXO1088_001355	COG0347	Belongs to the P(II) protein family
IXO1088_001360	COG0004	ammonium transporteR
IXO1088_001365	COG3852	Histidine kinase
IXO1088_001370	COG2204	response regulator
IXO1088_001375	COG2032	superoxide dismutase activity
IXO1088_001380	COG2032	superoxide dismutase activity
IXO1088_001450	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IXO1088_001455	COG1074	ATP-dependent DNA helicase activity
IXO1088_001465	COG3549	Plasmid maintenance system killer
IXO1088_001555	COG1764	response to oxidative stress
IXO1088_001560	COG1846	Transcriptional regulator
IXO1088_001610	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IXO1088_001650	COG2211	Major facilitator Superfamily
IXO1088_001675	COG3693	PFAM glycoside hydrolase, family 10
IXO1088_001700	COG0246	Mannitol dehydrogenase
IXO1088_001705	COG1472	Belongs to the glycosyl hydrolase 3 family
IXO1088_001715	COG4948	Mandelate Racemase Muconate Lactonizing
IXO1088_001725	COG3661	Belongs to the glycosyl hydrolase 67 family
IXO1088_001745	COG0037	tRNA processing
IXO1088_001750	COG2974	May be involved in recombination
IXO1088_001775	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
IXO1088_001785	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IXO1088_001795	COG0805	protein transport
IXO1088_001805	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IXO1088_001805	COG0519	Catalyzes the synthesis of GMP from XMP
IXO1088_001830	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IXO1088_001835	COG0752	glycyl-tRNA synthetase alpha subunit
IXO1088_001845	COG0457	Tetratricopeptide repeat
IXO1088_001850	COG4771	TonB-dependent receptor
IXO1088_001865	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IXO1088_001875	COG0697	spore germination
IXO1088_001885	COG0523	cobalamin synthesis protein
IXO1088_001940	COG1960	acyl-CoA dehydrogenase activity
IXO1088_001945	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IXO1088_001950	COG4770	biotin carboxylase activity
IXO1088_002005	COG2072	flavoprotein involved in K transport
IXO1088_002025	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IXO1088_002070	COG0084	hydrolase, TatD family'
IXO1088_002090	COG0583	DNA-binding transcription factor activity
IXO1088_002095	COG2814	Major facilitator Superfamily
IXO1088_002105	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IXO1088_002110	COG1902	pentaerythritol trinitrate reductase activity
IXO1088_002140	COG0745	RESPONSE REGULATOR receiver
IXO1088_002160	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IXO1088_002165	COG0583	DNA-binding transcription factor activity
IXO1088_002195	COG0702	epimerase
IXO1088_002200	COG1733	regulation of RNA biosynthetic process
IXO1088_002260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IXO1088_002275	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IXO1088_002310	COG2911	Protein conserved in bacteria
IXO1088_002315	COG0729	surface antigen
IXO1088_002330	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IXO1088_002335	COG3118	belongs to the thioredoxin family
IXO1088_002345	COG2884	Cell division ATP-binding protein ftsE
IXO1088_002350	COG2177	Part of the ABC transporter FtsEX involved in
IXO1088_002355	COG3437	response regulator, receiver
IXO1088_002360	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IXO1088_002365	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IXO1088_002375	COG1252	NADH dehydrogenase
IXO1088_002400	COG0459	protein refolding
IXO1088_002410	COG4771	TonB-dependent receptor
IXO1088_002425	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IXO1088_002470	COG3386	PFAM SMP-30 Gluconolaconase
IXO1088_002485	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IXO1088_002515	COG0778	Nitroreductase
IXO1088_002520	COG2353	YceI-like domain
IXO1088_002620	COG0408	coproporphyrinogen oxidase activity
IXO1088_002630	COG3039	Transposase
IXO1088_002655	COG0129	dihydroxy-acid dehydratase activity
IXO1088_002665	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IXO1088_002705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IXO1088_002710	COG0318	PFAM AMP-dependent synthetase and ligase
IXO1088_002715	COG0727	PFAM Uncharacterised protein family (UPF0153)
IXO1088_002720	COG0596	Alpha beta hydrolase
IXO1088_002735	COG2189	Belongs to the N(4) N(6)-methyltransferase family
IXO1088_002740	COG3177	Filamentation induced by cAMP protein fic
IXO1088_002745	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IXO1088_002760	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IXO1088_002785	COG4191	Histidine kinase
IXO1088_002805	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
IXO1088_002810	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IXO1088_002840	COG5383	Protein conserved in bacteria
IXO1088_002855	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IXO1088_002860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IXO1088_002865	COG1473	amidohydrolase
IXO1088_002875	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IXO1088_002875	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IXO1088_002980	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IXO1088_002995	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IXO1088_003000	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
IXO1088_003010	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
IXO1088_003015	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IXO1088_003020	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IXO1088_003070	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IXO1088_003085	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
IXO1088_003155	COG3039	Transposase
IXO1088_003180	COG1294	oxidase, subunit
IXO1088_003185	COG1271	oxidase subunit
IXO1088_003245	COG2972	Histidine kinase
IXO1088_003260	COG0531	amino acid
IXO1088_003280	COG3590	peptidase
IXO1088_003295	COG0667	Aldo Keto reductase
IXO1088_003310	COG3384	dioxygenase
IXO1088_003320	COG1573	uracil-dna glycosylase
IXO1088_003330	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
IXO1088_003345	COG0025	NhaP-type Na H and K H
IXO1088_003350	COG1131	(ABC) transporter
IXO1088_003355	COG0842	Transport permease protein
IXO1088_003370	COG1404	Belongs to the peptidase S8 family
IXO1088_003385	COG0745	RESPONSE REGULATOR receiver
IXO1088_003435	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IXO1088_003460	COG2202	Pas domain
IXO1088_003460	COG2205	protein histidine kinase activity
IXO1088_003490	COG2813	Specifically methylates the guanine in position
IXO1088_003495	COG1187	pseudouridine synthase activity
IXO1088_003500	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IXO1088_003535	COG0697	spore germination
IXO1088_003545	COG2011	ABC-type metal ion transport system permease component
IXO1088_003575	COG0508	dehydrogenase complex catalyzes the overall conversion of
IXO1088_003585	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IXO1088_003605	COG0356	it plays a direct role in the translocation of protons across the membrane
IXO1088_003615	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IXO1088_003625	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IXO1088_003630	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IXO1088_003635	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IXO1088_003640	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IXO1088_003690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IXO1088_003695	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IXO1088_003745	COG0339	signal peptide processing
IXO1088_003785	COG1956	GAF domain-containing protein
IXO1088_003790	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IXO1088_003800	COG0720	synthase
IXO1088_003810	COG0513	Belongs to the DEAD box helicase family
IXO1088_003825	COG0625	glutathione transferase activity
IXO1088_003855	COG0626	cystathionine gamma-synthase activity
IXO1088_003905	COG3328	transposase activity
IXO1088_003930	COG2086	electron transfer activity
IXO1088_003955	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
IXO1088_003955	COG0662	Cupin 2, conserved barrel domain protein
IXO1088_003960	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IXO1088_004000	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IXO1088_004000	COG3218	ABC-type transport auxiliary lipoprotein component
IXO1088_004005	COG1127	ABC transporter
IXO1088_004010	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IXO1088_004025	COG0442	prolyl-tRNA aminoacylation
IXO1088_004035	COG1183	phosphatidylcholine synthase activity
IXO1088_004070	COG3039	Transposase
IXO1088_004095	COG3039	Transposase
IXO1088_004125	COG0525	valine-tRNA ligase activity
IXO1088_004140	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IXO1088_004150	COG0795	lipopolysaccharide-transporting ATPase activity
IXO1088_004165	COG4974	Belongs to the 'phage' integrase family
IXO1088_004170	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IXO1088_004175	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IXO1088_004175	COG0047	phosphoribosylformylglycinamidine synthase activity
IXO1088_004185	COG5295	Hep Hag repeat protein
IXO1088_004195	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IXO1088_004205	COG1459	type II secretion system
IXO1088_004210	COG2165	general secretion pathway protein
IXO1088_004215	COG4970	Tfp pilus assembly protein FimT
IXO1088_004220	COG2165	general secretion pathway protein
IXO1088_004225	COG4795	General secretion pathway protein
IXO1088_004230	COG3156	type II secretion system protein K
IXO1088_004235	COG3166	PFAM Fimbrial assembly family protein
IXO1088_004250	COG1450	Type ii and iii secretion system protein
IXO1088_004260	COG2188	Transcriptional regulator
IXO1088_004320	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IXO1088_004325	COG1518	maintenance of DNA repeat elements
IXO1088_004370	COG1399	metal-binding, possibly nucleic acid-binding protein
IXO1088_004395	COG1028	Short-chain dehydrogenase reductase Sdr
IXO1088_004400	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IXO1088_004410	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IXO1088_004415	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IXO1088_004450	COG3829	transcription factor binding
IXO1088_004560	COG2826	transposase and inactivated derivatives, IS30 family
IXO1088_004570	COG0678	peroxiredoxin activity
IXO1088_004590	COG0330	HflC and HflK could
IXO1088_004595	COG0330	HflC and HflK could
IXO1088_004605	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IXO1088_004610	COG0308	aminopeptidase N
IXO1088_004660	COG1560	Kdo2-lipid A biosynthetic process
IXO1088_004665	COG1519	Transferase
IXO1088_004670	COG1538	Outer membrane efflux protein
IXO1088_004675	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IXO1088_004705	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IXO1088_004710	COG0066	3-isopropylmalate dehydratase activity
IXO1088_004745	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IXO1088_004755	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IXO1088_004760	COG3710	Transcriptional regulator
IXO1088_004785	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IXO1088_004795	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
IXO1088_004805	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
IXO1088_004835	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IXO1088_004845	COG3781	membrane
IXO1088_005015	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
IXO1088_005040	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IXO1088_005085	COG3039	Transposase
IXO1088_005110	COG0584	glycerophosphoryl diester phosphodiesterase
IXO1088_005140	COG0446	pyridine nucleotide-disulphide oxidoreductase
IXO1088_005140	COG1902	pentaerythritol trinitrate reductase activity
IXO1088_005145	COG0604	alcohol dehydrogenase
IXO1088_005175	COG0156	8-amino-7-oxononanoate synthase activity
IXO1088_005180	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IXO1088_005185	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IXO1088_005190	COG4208	sulfate ABC transporter
IXO1088_005195	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IXO1088_005230	COG0588	phosphoglycerate mutase activity
IXO1088_005240	COG0285	dihydrofolate synthase activity
IXO1088_005260	COG2833	Protein of unknown function (DUF455)
IXO1088_005280	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IXO1088_005285	COG0671	phosphoesterase, PA-phosphatase related
IXO1088_005290	COG0438	transferase activity, transferring glycosyl groups
IXO1088_005300	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IXO1088_005315	COG4783	chaperone-mediated protein folding
IXO1088_005340	COG0473	3-isopropylmalate dehydrogenase activity
IXO1088_005395	COG0544	peptidyl-prolyl cis-trans isomerase activity
IXO1088_005435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IXO1088_005460	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IXO1088_005470	COG0631	protein serine/threonine phosphatase activity
IXO1088_005495	COG3501	Rhs element vgr protein
IXO1088_005525	COG0582	viral genome integration into host DNA
IXO1088_005535	COG0859	PFAM glycosyl transferase family 9
IXO1088_005540	COG3642	lipopolysaccharide core region biosynthetic process
IXO1088_005545	COG1234	tRNA 3'-trailer cleavage
IXO1088_005550	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IXO1088_005560	COG0315	cyclic pyranopterin monophosphate synthase activity
IXO1088_005565	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IXO1088_005570	COG0314	molybdopterin synthase activity
IXO1088_005600	COG0537	adenosine 5'-monophosphoramidase activity
IXO1088_005620	COG0714	Associated with various cellular activities
IXO1088_005640	COG0242	peptide deformylase activity
IXO1088_005690	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IXO1088_005695	COG0726	polysaccharide deacetylase
IXO1088_005720	COG1162	GTPase activity
IXO1088_005755	COG1609	Transcriptional regulator
IXO1088_005760	COG1028	Short-chain dehydrogenase reductase Sdr
IXO1088_005765	COG2851	Citrate transporter
IXO1088_005785	COG0642	Histidine kinase
IXO1088_005795	COG2197	response regulator
IXO1088_005815	COG0583	DNA-binding transcription factor activity
IXO1088_005830	COG4191	Histidine kinase
IXO1088_005850	COG0281	malic enzyme
IXO1088_005850	COG0280	phosphate acetyltransferase
IXO1088_005915	COG0352	thiamine-phosphate diphosphorylase activity
IXO1088_005920	COG1773	rubredoxin
IXO1088_005925	COG2912	Transglutaminase-like superfamily
IXO1088_005935	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IXO1088_005945	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IXO1088_005970	COG0006	proline dipeptidase activity
IXO1088_006000	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IXO1088_006010	COG0346	lactoylglutathione lyase activity
IXO1088_006015	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IXO1088_006020	COG1561	YicC-like family, N-terminal region
IXO1088_006045	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IXO1088_006055	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IXO1088_006080	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
IXO1088_006120	COG0714	Associated with various cellular activities
IXO1088_006140	COG2304	oxidoreductase activity
IXO1088_006160	COG1301	dicarboxylic acid transport
IXO1088_006165	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IXO1088_006175	COG0739	heme binding
IXO1088_006180	COG1376	ErfK ybiS ycfS ynhG family protein
IXO1088_006205	COG1022	Amp-dependent synthetase and ligase
IXO1088_006215	COG1028	Short-chain dehydrogenase reductase Sdr
IXO1088_006225	COG0745	RESPONSE REGULATOR receiver
IXO1088_006230	COG0642	Histidine kinase
IXO1088_006250	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IXO1088_006255	COG4149	molybdate abc transporter
IXO1088_006260	COG0725	ABC transporter, periplasmic molybdate-binding protein
IXO1088_006265	COG3453	Protein conserved in bacteria
IXO1088_006265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IXO1088_006300	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IXO1088_006320	COG2205	protein histidine kinase activity
IXO1088_006325	COG0745	RESPONSE REGULATOR receiver
IXO1088_006345	COG3039	Transposase
IXO1088_006380	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IXO1088_006385	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IXO1088_006445	COG3039	Transposase
IXO1088_006450	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IXO1088_006475	COG2201	protein-glutamate methylesterase activity
IXO1088_006555	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IXO1088_006565	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IXO1088_006570	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IXO1088_006585	COG1842	Phage shock protein A
IXO1088_006610	COG0754	glutathionylspermidine amidase activity
IXO1088_006680	COG0531	amino acid
IXO1088_006685	COG2197	response regulator
IXO1088_006700	COG1113	amino acid transport
IXO1088_006720	COG1271	oxidase subunit
IXO1088_006725	COG1294	oxidase, subunit
IXO1088_006735	COG2239	Acts as a magnesium transporter
IXO1088_006745	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IXO1088_006750	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IXO1088_006760	COG1660	Displays ATPase and GTPase activities
IXO1088_006765	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IXO1088_006770	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IXO1088_006785	COG1137	ATPase activity
IXO1088_006790	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IXO1088_006800	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IXO1088_006810	COG0271	Belongs to the BolA IbaG family
IXO1088_006815	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IXO1088_006835	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IXO1088_006850	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IXO1088_006860	COG0628	permease
IXO1088_006870	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IXO1088_006875	COG3178	'Phosphotransferase
IXO1088_006890	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IXO1088_006895	COG1555	photosystem II stabilization
IXO1088_006910	COG3039	Transposase
IXO1088_006950	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IXO1088_006965	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IXO1088_006990	COG0228	four-way junction DNA binding
IXO1088_006995	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IXO1088_007000	COG0336	Belongs to the RNA methyltransferase TrmD family
IXO1088_007015	COG0534	Mate efflux family protein
IXO1088_007060	COG0542	response to heat
IXO1088_007100	COG4206	TonB-dependent receptor
IXO1088_007165	COG0019	diaminopimelate decarboxylase activity
IXO1088_007175	COG2814	Major facilitator Superfamily
IXO1088_007180	COG4264	IucA IucC family
IXO1088_007190	COG4772	TonB-dependent receptor
IXO1088_007205	COG4651	solute:proton antiporter activity
IXO1088_007205	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IXO1088_007230	COG0488	(ABC) transporter
IXO1088_007255	COG2755	lipolytic protein G-D-S-L family
IXO1088_007255	COG0657	acetylesterase activity
IXO1088_007280	COG2207	Transcriptional regulator
IXO1088_007285	COG0326	Molecular chaperone. Has ATPase activity
IXO1088_007315	COG3328	transposase activity
IXO1088_007320	COG0174	glutamine synthetase
IXO1088_007325	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
IXO1088_007335	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IXO1088_007350	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IXO1088_007385	COG2146	nitrite reductase [NAD(P)H] activity
IXO1088_007400	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IXO1088_007405	COG0719	Fe-S assembly protein
IXO1088_007410	COG0396	ATPase activity
IXO1088_007415	COG0719	Fe-S assembly protein
IXO1088_007420	COG1959	2 iron, 2 sulfur cluster binding
IXO1088_007440	COG0693	protein deglycase activity
IXO1088_007480	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IXO1088_007515	COG0519	Catalyzes the synthesis of GMP from XMP
IXO1088_007525	COG1678	Uncharacterized ACR, COG1678
IXO1088_007530	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IXO1088_007545	COG1764	response to oxidative stress
IXO1088_007555	COG0384	phenazine biosynthesis protein PhzF
IXO1088_007565	COG0527	aspartate kinase activity
IXO1088_007595	COG0142	geranyltranstransferase activity
IXO1088_007600	COG0629	single-stranded DNA binding
IXO1088_007660	COG2879	small protein
IXO1088_007665	COG1966	Carbon starvation protein
IXO1088_007670	COG1741	Belongs to the pirin family
IXO1088_007680	COG3501	Rhs element vgr protein
IXO1088_007725	COG3179	chitinase
IXO1088_007730	COG3501	Rhs element vgr protein
IXO1088_007740	COG3328	transposase activity
IXO1088_007760	COG3179	chitinase
IXO1088_007800	COG3501	Rhs element vgr protein
IXO1088_007865	COG3501	Rhs element vgr protein
IXO1088_007965	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
IXO1088_007975	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
IXO1088_008010	COG0732	type I restriction modification DNA specificity domain
IXO1088_008105	COG0587	DNA-directed DNA polymerase activity
IXO1088_008125	COG1297	OPT oligopeptide transporter protein
IXO1088_008150	COG1506	peptidase
IXO1088_008150	COG0823	Involved in the tonB-independent uptake of proteins
IXO1088_008170	COG2207	Transcriptional regulator
IXO1088_008170	COG1917	Cupin 2, conserved barrel domain protein
IXO1088_008200	COG0753	catalase activity
IXO1088_008235	COG0126	phosphoglycerate kinase activity
IXO1088_008245	COG0469	pyruvate kinase activity
IXO1088_008255	COG3588	fructose-bisphosphate aldolase
IXO1088_008260	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
IXO1088_008310	COG2205	protein histidine kinase activity
IXO1088_008310	COG2198	Histidine kinase
IXO1088_008310	COG0784	Response regulator, receiver
IXO1088_008330	COG0175	sulfate reduction
IXO1088_008335	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IXO1088_008340	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IXO1088_008345	COG0175	sulfate reduction
IXO1088_008350	COG0529	Catalyzes the synthesis of activated sulfate
IXO1088_008350	COG2895	sulfate adenylyltransferase (ATP) activity
IXO1088_008365	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IXO1088_008370	COG0308	aminopeptidase N
IXO1088_008400	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IXO1088_008425	COG1970	mechanosensitive ion channel activity
IXO1088_008455	COG0471	metal ion transport
IXO1088_008455	COG3273	potassium ion transport
IXO1088_008470	COG2022	thiamine diphosphate biosynthetic process
IXO1088_008665	COG0632	four-way junction helicase activity
IXO1088_008675	COG2255	four-way junction helicase activity
IXO1088_008680	COG0824	Thioesterase
IXO1088_008690	COG0848	biopolymer transport protein
IXO1088_008705	COG2885	chlorophyll binding
IXO1088_008715	COG0602	queuosine metabolic process
IXO1088_008740	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IXO1088_008765	COG0514	ATP-dependent DNA helicase (RecQ)
IXO1088_008770	COG0783	Belongs to the Dps family
IXO1088_008775	COG1643	Atp-dependent helicase
IXO1088_008800	COG0535	radical SAM domain protein
IXO1088_008805	COG0535	radical SAM domain protein
IXO1088_008810	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
IXO1088_008825	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IXO1088_008835	COG1215	transferase activity, transferring glycosyl groups
IXO1088_008840	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IXO1088_008850	COG1199	ATP-dependent helicase activity
IXO1088_008860	COG1397	ADP-ribosylglycohydrolase
IXO1088_008870	COG0189	ligase activity
IXO1088_008885	COG0835	chemotaxis
IXO1088_008890	COG0840	transmembrane signaling receptor activity
IXO1088_008895	COG2198	Histidine kinase
IXO1088_008895	COG0784	Response regulator, receiver
IXO1088_008895	COG0643	Histidine kinase
IXO1088_008945	COG1446	asparaginase
IXO1088_009000	COG3537	Alpha-1,2-mannosidase
IXO1088_009065	COG1472	Belongs to the glycosyl hydrolase 3 family
IXO1088_009085	COG3858	chitin binding
IXO1088_009085	COG1388	LysM domain
IXO1088_009100	COG0837	glucose binding
IXO1088_009105	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IXO1088_009115	COG0494	nUDIX hydrolase
IXO1088_009125	COG3956	TIGRFAM MazG family protein
IXO1088_009140	COG0330	HflC and HflK could
IXO1088_009155	COG0509	glycine decarboxylation via glycine cleavage system
IXO1088_009190	COG1960	acyl-CoA dehydrogenase activity
IXO1088_009200	COG1309	transcriptional regulator
IXO1088_009205	COG4771	TonB-dependent receptor
IXO1088_009215	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IXO1088_009225	COG0463	Glycosyl transferase, family 2
IXO1088_009245	COG1272	protein, Hemolysin III
IXO1088_009250	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IXO1088_009255	COG0739	heme binding
IXO1088_009260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IXO1088_009265	COG0626	cystathionine gamma-synthase activity
IXO1088_009275	COG1760	l-serine dehydratase
IXO1088_009290	COG2353	YceI-like domain
IXO1088_009300	COG2353	YceI-like domain
IXO1088_009370	COG1960	acyl-CoA dehydrogenase activity
IXO1088_009375	COG1024	Enoyl-CoA hydratase
IXO1088_009395	COG1250	3-hydroxyacyl-CoA dehydrogenase
IXO1088_009395	COG1024	Enoyl-CoA hydratase
IXO1088_009410	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IXO1088_009440	COG1381	Involved in DNA repair and RecF pathway recombination
IXO1088_009455	COG2954	triphosphatase activity
IXO1088_009470	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IXO1088_009475	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
IXO1088_009480	COG3046	protein related to deoxyribodipyrimidine photolyase
IXO1088_009495	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IXO1088_009500	COG1278	Cold shock
IXO1088_009520	COG1201	RNA secondary structure unwinding
IXO1088_009525	COG1793	dna ligase
IXO1088_009535	COG1793	dna ligase
IXO1088_009535	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
IXO1088_009565	COG0183	Belongs to the thiolase family
IXO1088_009590	COG1451	nucleotide metabolic process
IXO1088_009610	COG3039	Transposase
IXO1088_009615	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IXO1088_009675	COG1047	Peptidyl-prolyl cis-trans
IXO1088_009690	COG2824	Alkylphosphonate utilization operon protein PhnA
IXO1088_009705	COG1902	pentaerythritol trinitrate reductase activity
IXO1088_009710	COG2814	Major facilitator Superfamily
IXO1088_009755	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IXO1088_009755	COG0392	lysyltransferase activity
IXO1088_009765	COG0251	oxidation-reduction process
IXO1088_009770	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IXO1088_009785	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IXO1088_009810	COG1595	DNA-templated transcription, initiation
IXO1088_009830	COG2878	Part of a membrane complex involved in electron transport
IXO1088_009840	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IXO1088_009840	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IXO1088_009860	COG0833	amino acid
IXO1088_009865	COG2040	homocysteine
IXO1088_009880	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IXO1088_009920	COG0529	Catalyzes the synthesis of activated sulfate
IXO1088_009920	COG2895	sulfate adenylyltransferase (ATP) activity
IXO1088_009995	COG4771	TonB-dependent receptor
IXO1088_010005	COG0825	malonyl-CoA metabolic process
IXO1088_010025	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IXO1088_010030	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IXO1088_010055	COG0750	zinc metalloprotease
IXO1088_010065	COG0575	Belongs to the CDS family
IXO1088_010075	COG0233	cytoplasmic translational termination
IXO1088_010090	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IXO1088_010150	COG1393	Belongs to the ArsC family
IXO1088_010165	COG0367	asparagine synthase
IXO1088_010175	COG4774	siderophore transport
IXO1088_010210	COG2207	Transcriptional regulator
IXO1088_010225	COG1566	PFAM secretion protein HlyD family protein
IXO1088_010230	COG2814	Major facilitator Superfamily
IXO1088_010275	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IXO1088_010285	COG1960	acyl-CoA dehydrogenase activity
IXO1088_010300	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IXO1088_010310	COG2914	Belongs to the UPF0125 (RnfH) family
IXO1088_010320	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IXO1088_010330	COG0497	DNA recombination
IXO1088_010340	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IXO1088_010345	COG0443	Heat shock 70 kDa protein
IXO1088_010350	COG0484	heat shock protein binding
IXO1088_010360	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
IXO1088_010380	COG0583	DNA-binding transcription factor activity
IXO1088_010395	COG1132	(ABC) transporter
IXO1088_010430	COG2850	peptidyl-arginine hydroxylation
IXO1088_010510	COG1131	(ABC) transporter
IXO1088_010515	COG1725	Transcriptional regulator
IXO1088_010525	COG0386	Belongs to the glutathione peroxidase family
IXO1088_010540	COG2900	Belongs to the SlyX family
IXO1088_010565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IXO1088_010580	COG0646	methionine synthase
IXO1088_010580	COG1410	methionine synthase
IXO1088_010585	COG1410	methionine synthase
IXO1088_010585	COG0646	methionine synthase
IXO1088_010590	COG2226	methyltransferase
IXO1088_010595	COG1960	acyl-CoA dehydrogenase activity
IXO1088_010625	COG0557	exoribonuclease II activity
IXO1088_010640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IXO1088_010655	COG3039	Transposase
IXO1088_010685	COG1278	Cold shock
IXO1088_010770	COG3039	Transposase
IXO1088_010780	COG0583	DNA-binding transcription factor activity
IXO1088_010855	COG0742	ribosomal rna small subunit methyltransferase
IXO1088_010860	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IXO1088_010875	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IXO1088_010880	COG0405	Gamma-glutamyltransferase
IXO1088_010960	COG3501	Rhs element vgr protein
IXO1088_010980	COG3501	Rhs element vgr protein
IXO1088_011005	COG3039	Transposase
IXO1088_011045	COG0343	queuine tRNA-ribosyltransferase activity
IXO1088_011050	COG1862	Preprotein translocase
IXO1088_011055	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IXO1088_011060	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IXO1088_011090	COG3328	transposase activity
IXO1088_011105	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IXO1088_011115	COG0704	Plays a role in the regulation of phosphate uptake
IXO1088_011130	COG0573	inorganic phosphate transmembrane transporter activity
IXO1088_011135	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IXO1088_011170	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IXO1088_011180	COG1024	Enoyl-CoA hydratase
IXO1088_011190	COG0494	nUDIX hydrolase
IXO1088_011235	COG0116	Belongs to the methyltransferase superfamily
IXO1088_011235	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IXO1088_011260	COG0667	Aldo Keto reductase
IXO1088_011270	COG2925	Exonuclease
IXO1088_011300	COG0288	reversible hydration of carbon dioxide
IXO1088_011335	COG0316	Belongs to the HesB IscA family
IXO1088_011340	COG0360	Binds together with S18 to 16S ribosomal RNA
IXO1088_011350	COG0359	binds to the 23S rRNA
IXO1088_011360	COG3115	cell septum assembly
IXO1088_011375	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
IXO1088_011390	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IXO1088_011415	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IXO1088_011425	COG2986	histidine ammonia-lyase
IXO1088_011430	COG1228	amidohydrolase
IXO1088_011475	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IXO1088_011485	COG0077	Prephenate dehydratase
IXO1088_011485	COG1605	Chorismate mutase
IXO1088_011490	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IXO1088_011520	COG4566	intracellular signal transduction
IXO1088_011575	COG0860	N-Acetylmuramoyl-L-alanine amidase
IXO1088_011580	COG1469	GTP cyclohydrolase I activity
IXO1088_011590	COG0617	tRNA 3'-terminal CCA addition
IXO1088_011600	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IXO1088_011605	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IXO1088_011640	COG1472	Belongs to the glycosyl hydrolase 3 family
IXO1088_011660	COG4251	negative regulation of phosphorylation
IXO1088_011660	COG2203	Gaf domain
IXO1088_011660	COG3706	GGDEF domain
IXO1088_011660	COG5001	Diguanylate cyclase
IXO1088_011750	COG0386	Belongs to the glutathione peroxidase family
IXO1088_011810	COG3706	GGDEF domain
IXO1088_011835	COG1247	-acetyltransferase
IXO1088_011855	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IXO1088_011860	COG3039	Transposase
IXO1088_011870	COG3039	Transposase
IXO1088_011900	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IXO1088_011915	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IXO1088_011920	COG1393	Belongs to the ArsC family
IXO1088_011925	COG0431	NADPH-dependent FMN reductase
IXO1088_011930	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IXO1088_011935	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IXO1088_011955	COG0784	Response regulator, receiver
IXO1088_011955	COG2205	protein histidine kinase activity
IXO1088_011955	COG5002	protein histidine kinase activity
IXO1088_011990	COG0800	Aldolase
IXO1088_011995	COG0129	dihydroxy-acid dehydratase activity
IXO1088_012000	COG0363	glucosamine-6-phosphate deaminase activity
IXO1088_012010	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IXO1088_012025	COG0354	folic acid binding
IXO1088_012040	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IXO1088_012055	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IXO1088_012070	COG4591	ABC-type transport system involved in lipoprotein release permease component
IXO1088_012095	COG0811	peptide transport
IXO1088_012110	COG1663	tetraacyldisaccharide 4'-kinase activity
IXO1088_012120	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IXO1088_012130	COG0322	excinuclease ABC activity
IXO1088_012180	COG2801	Transposase and inactivated derivatives
IXO1088_012220	COG0653	protein targeting
IXO1088_012385	COG0140	phosphoribosyl-ATP diphosphatase activity
IXO1088_012385	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IXO1088_012395	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IXO1088_012405	COG0131	Imidazoleglycerol-phosphate dehydratase
IXO1088_012405	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IXO1088_012420	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IXO1088_012450	COG0124	histidyl-tRNA synthetase
IXO1088_012470	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IXO1088_012505	COG1012	belongs to the aldehyde dehydrogenase family
IXO1088_012535	COG0697	spore germination
IXO1088_012545	COG1794	racemase activity, acting on amino acids and derivatives
IXO1088_012575	COG0671	phosphoesterase, PA-phosphatase related
IXO1088_012590	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
IXO1088_012605	COG2183	response to ionizing radiation
IXO1088_012615	COG0723	plastoquinol--plastocyanin reductase activity
IXO1088_012615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IXO1088_012630	COG3243	poly(R)-hydroxyalkanoic acid synthase
IXO1088_012640	COG1183	phosphatidylcholine synthase activity
IXO1088_012645	COG1028	Short-chain dehydrogenase reductase Sdr
IXO1088_012660	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
IXO1088_012670	COG0668	transmembrane transport
IXO1088_012690	COG1914	H( )-stimulated, divalent metal cation uptake system
IXO1088_012740	COG0583	DNA-binding transcription factor activity
IXO1088_012745	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IXO1088_012750	COG3002	Belongs to the UPF0753 family
IXO1088_012765	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IXO1088_012785	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IXO1088_012795	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IXO1088_012800	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
IXO1088_012810	COG0776	regulation of translation
IXO1088_012815	COG0539	negative regulation of cytoplasmic translation
IXO1088_012820	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IXO1088_012835	COG2957	Belongs to the agmatine deiminase family
IXO1088_012845	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IXO1088_012870	COG0395	ABC-type sugar transport system, permease component
IXO1088_012875	COG1175	transmembrane transport
IXO1088_012915	COG2350	Protein conserved in bacteria
IXO1088_012920	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IXO1088_012925	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IXO1088_012930	COG1187	pseudouridine synthase activity
IXO1088_012955	COG0436	Aminotransferase
IXO1088_012960	COG4133	protoheme IX ABC transporter activity
IXO1088_013020	COG0277	FAD linked oxidase domain protein
IXO1088_013025	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IXO1088_013035	COG0531	amino acid
IXO1088_013040	COG0531	amino acid
IXO1088_013050	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
IXO1088_013080	COG3039	Transposase
IXO1088_013095	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IXO1088_013165	COG0303	'Molybdopterin
IXO1088_013170	COG1160	GTP binding
IXO1088_013175	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IXO1088_013185	COG1426	Protein conserved in bacteria
IXO1088_013195	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IXO1088_013210	COG1024	Enoyl-CoA hydratase
IXO1088_013210	COG1250	3-hydroxyacyl-CoA dehydrogenase
IXO1088_013215	COG0183	Belongs to the thiolase family
IXO1088_013225	COG0038	chloride channel
IXO1088_013245	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IXO1088_013270	COG1674	ftsk spoiiie
IXO1088_013275	COG0492	ferredoxin-NADP+ reductase activity
IXO1088_013300	COG0542	response to heat
IXO1088_013315	COG0482	sulfurtransferase activity
IXO1088_013340	COG5001	Diguanylate cyclase
IXO1088_013345	COG4585	Histidine kinase
IXO1088_013355	COG5002	protein histidine kinase activity
IXO1088_013375	COG0835	chemotaxis
IXO1088_013375	COG0784	Response regulator, receiver
IXO1088_013385	COG1558	bacterial-type flagellum-dependent cell motility
IXO1088_013390	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
IXO1088_013400	COG4787	bacterial-type flagellum-dependent cell motility
IXO1088_013440	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IXO1088_013445	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IXO1088_013475	COG2201	protein-glutamate methylesterase activity
IXO1088_013495	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IXO1088_013505	COG1028	Short-chain dehydrogenase reductase Sdr
IXO1088_013540	COG1677	Flagellar hook-basal body complex protein FliE
IXO1088_013590	COG3190	flagellar
IXO1088_013610	COG1684	flagellar biosynthetic protein fliR
IXO1088_013615	COG5001	Diguanylate cyclase
IXO1088_013615	COG3300	MHYT domain
IXO1088_013620	COG5001	Diguanylate cyclase
IXO1088_013620	COG3300	MHYT domain
IXO1088_013665	COG0784	Response regulator, receiver
IXO1088_013665	COG2198	Histidine kinase
IXO1088_013665	COG0643	Histidine kinase
IXO1088_013705	COG3209	COG3209 Rhs family protein
IXO1088_013805	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IXO1088_013810	COG4988	ABC transporter
IXO1088_013820	COG1271	oxidase subunit
IXO1088_013850	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IXO1088_013870	COG0165	Argininosuccinate lyase
IXO1088_013885	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IXO1088_013890	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IXO1088_013900	COG0137	argininosuccinate synthase activity
IXO1088_013905	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IXO1088_013920	COG2166	iron-sulfur cluster assembly
IXO1088_013945	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IXO1088_013980	COG3039	Transposase
IXO1088_014000	COG4677	pectinesterase activity
IXO1088_014025	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IXO1088_014030	COG0402	S-adenosylhomocysteine deaminase activity
IXO1088_014045	COG1509	lysine 2,3-aminomutase activity
IXO1088_014050	COG5001	Diguanylate cyclase
IXO1088_014050	COG3300	MHYT domain
IXO1088_014065	COG0483	inositol monophosphate 1-phosphatase activity
IXO1088_014070	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IXO1088_014100	COG0513	Belongs to the DEAD box helicase family
IXO1088_014105	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IXO1088_014120	COG0625	glutathione transferase activity
IXO1088_014125	COG1278	Cold shock
IXO1088_014130	COG1671	Belongs to the UPF0178 family
IXO1088_014135	COG4681	YaeQ
IXO1088_014140	COG2081	HI0933 family
IXO1088_014150	COG0501	Belongs to the peptidase M48B family
IXO1088_014160	COG1028	Short-chain dehydrogenase reductase Sdr
IXO1088_014185	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IXO1088_014190	COG0860	N-Acetylmuramoyl-L-alanine amidase
IXO1088_014195	COG0802	atpase or kinase
IXO1088_014200	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IXO1088_014200	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IXO1088_014205	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IXO1088_014225	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IXO1088_014315	COG3328	transposase activity
IXO1088_014360	COG2969	positive regulation of protein catabolic process
IXO1088_014365	COG0625	glutathione transferase activity
IXO1088_014370	COG2857	Cytochrome c1
IXO1088_014375	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IXO1088_014380	COG0723	plastoquinol--plastocyanin reductase activity
IXO1088_014390	COG0741	lytic transglycosylase activity
IXO1088_014410	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IXO1088_014415	COG1702	phosphate starvation-inducible protein PhoH
IXO1088_014435	COG4535	Mg2 and Co2 transporter CorC
IXO1088_014450	COG1012	belongs to the aldehyde dehydrogenase family
IXO1088_014460	COG1177	transmembrane transport
IXO1088_014470	COG3842	ATPase activity
IXO1088_014515	COG0174	glutamine synthetase
IXO1088_014520	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IXO1088_014530	COG0477	Major facilitator Superfamily
IXO1088_014540	COG0243	molybdopterin cofactor binding
IXO1088_014550	COG2223	nitrite transmembrane transporter activity
IXO1088_014565	COG1121	(ABC) transporter
IXO1088_014575	COG2733	membrane
IXO1088_014580	COG0784	Response regulator, receiver
IXO1088_014580	COG2205	protein histidine kinase activity
IXO1088_014580	COG5002	protein histidine kinase activity
IXO1088_014590	COG3039	Transposase
IXO1088_014600	COG2902	Dehydrogenase
IXO1088_014610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IXO1088_014615	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IXO1088_014635	COG1609	Transcriptional regulator
IXO1088_014640	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IXO1088_014640	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IXO1088_014645	COG1105	Belongs to the carbohydrate kinase PfkB family
IXO1088_014650	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IXO1088_014650	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IXO1088_014665	COG3039	Transposase
IXO1088_014685	COG3039	Transposase
IXO1088_014750	COG3501	Rhs element vgr protein
IXO1088_014795	COG3039	Transposase
IXO1088_014850	COG4771	TonB-dependent receptor
IXO1088_014860	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IXO1088_014880	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IXO1088_014885	COG1360	Flagellar Motor Protein
IXO1088_014895	COG0835	chemotaxis
IXO1088_014905	COG0745	RESPONSE REGULATOR receiver
IXO1088_014935	COG0840	transmembrane signaling receptor activity
IXO1088_014950	COG0840	transmembrane signaling receptor activity
IXO1088_014960	COG0840	transmembrane signaling receptor activity
IXO1088_014970	COG0840	transmembrane signaling receptor activity
IXO1088_014975	COG0840	transmembrane signaling receptor activity
IXO1088_014980	COG0840	transmembrane signaling receptor activity
IXO1088_014985	COG0840	transmembrane signaling receptor activity
IXO1088_015005	COG0835	chemotaxis
IXO1088_015065	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IXO1088_015095	COG0318	PFAM AMP-dependent synthetase and ligase
IXO1088_015100	COG1024	Enoyl-CoA hydratase
IXO1088_015105	COG2205	protein histidine kinase activity
IXO1088_015105	COG2198	Histidine kinase
IXO1088_015105	COG0784	Response regulator, receiver
IXO1088_015180	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IXO1088_015190	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IXO1088_015195	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IXO1088_015205	COG0505	Belongs to the CarA family
IXO1088_015210	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IXO1088_015220	COG2258	MOSC domain
IXO1088_015225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IXO1088_015275	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IXO1088_015295	COG0477	Major facilitator Superfamily
IXO1088_015305	COG1070	Carbohydrate kinase
IXO1088_015315	COG1501	Belongs to the glycosyl hydrolase 31 family
IXO1088_015330	COG0800	Aldolase
IXO1088_015335	COG4948	Mandelate Racemase Muconate Lactonizing
IXO1088_015345	COG3734	2-keto-3-deoxy-galactonokinase
IXO1088_015350	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IXO1088_015360	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IXO1088_015375	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IXO1088_015380	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
IXO1088_015390	COG0351	phosphomethylpyrimidine kinase
IXO1088_015420	COG0583	DNA-binding transcription factor activity
IXO1088_015425	COG1741	Belongs to the pirin family
IXO1088_015450	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IXO1088_015455	COG0305	Participates in initiation and elongation during chromosome replication
IXO1088_015475	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IXO1088_015480	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IXO1088_015485	COG2137	regulation of response to DNA damage stimulus
IXO1088_015490	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IXO1088_015505	COG1546	Belongs to the CinA family
IXO1088_015510	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IXO1088_015520	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IXO1088_015525	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IXO1088_015535	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
IXO1088_015540	COG1534	Rna-binding protein
IXO1088_015555	COG1238	metal cluster binding
IXO1088_015560	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IXO1088_015565	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
IXO1088_015570	COG2840	Smr protein MutS2
IXO1088_015580	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
IXO1088_015590	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
IXO1088_015595	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IXO1088_015600	COG0148	phosphopyruvate hydratase activity
IXO1088_015610	COG2877	3-deoxy-8-phosphooctulonate synthase activity
IXO1088_015615	COG0504	CTP synthase activity
IXO1088_015640	COG1434	Gram-negative-bacterium-type cell wall biogenesis
IXO1088_015645	COG0306	phosphate transporter
IXO1088_015660	COG1253	flavin adenine dinucleotide binding
IXO1088_015675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IXO1088_015695	COG0477	Major facilitator Superfamily
IXO1088_015705	COG1132	(ABC) transporter
IXO1088_015710	COG1136	(ABC) transporter
IXO1088_015725	COG0438	transferase activity, transferring glycosyl groups
IXO1088_015735	COG2264	protein methyltransferase activity
IXO1088_015765	COG2244	polysaccharide biosynthetic process
IXO1088_015815	COG1595	DNA-templated transcription, initiation
IXO1088_015830	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IXO1088_015850	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IXO1088_015910	COG2201	protein-glutamate methylesterase activity
IXO1088_015930	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IXO1088_015935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IXO1088_015985	COG1858	cytochrome C peroxidase
IXO1088_016015	COG0515	serine threonine protein kinase
IXO1088_016020	COG0631	protein serine/threonine phosphatase activity
IXO1088_016055	COG3501	Rhs element vgr protein
IXO1088_016135	COG3039	Transposase
IXO1088_016165	COG3039	Transposase
IXO1088_016170	COG3039	Transposase
IXO1088_016195	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
IXO1088_016195	COG0316	Belongs to the HesB IscA family
IXO1088_016200	COG2154	pterin-4-alpha-carbinolamine dehydratase
IXO1088_016210	COG0428	transporter
IXO1088_016215	COG0428	transporter
IXO1088_016220	COG3064	Membrane
IXO1088_016230	COG1530	ribonuclease E activity
IXO1088_016270	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IXO1088_016305	COG3039	Transposase
IXO1088_016335	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IXO1088_016335	COG1648	precorrin-2 dehydrogenase activity
IXO1088_016360	COG0746	molybdenum cofactor guanylyltransferase activity
IXO1088_016385	COG3039	Transposase
IXO1088_016445	COG4206	TonB-dependent receptor
IXO1088_016495	COG0531	amino acid
IXO1088_016510	COG0006	proline dipeptidase activity
IXO1088_016520	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IXO1088_016535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IXO1088_016540	COG3938	Belongs to the proline racemase family
IXO1088_016550	COG0552	protein localization to endoplasmic reticulum
IXO1088_016575	COG0784	Response regulator, receiver
IXO1088_016575	COG4191	Histidine kinase
IXO1088_016670	COG3040	lipid binding
IXO1088_016710	COG0438	transferase activity, transferring glycosyl groups
IXO1088_016720	COG0438	transferase activity, transferring glycosyl groups
IXO1088_016725	COG0438	transferase activity, transferring glycosyl groups
IXO1088_016780	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IXO1088_016785	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IXO1088_016795	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IXO1088_016835	COG0556	nucleotide-excision repair
IXO1088_016840	COG4969	Belongs to the N-Me-Phe pilin family
IXO1088_016905	COG4695	Portal protein
IXO1088_016950	COG3179	chitinase
IXO1088_017165	COG1611	Belongs to the LOG family
IXO1088_017180	COG2095	MarC family integral membrane protein
IXO1088_017190	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IXO1088_017225	COG1185	polyribonucleotide nucleotidyltransferase activity
IXO1088_017230	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IXO1088_017250	COG0195	Participates in both transcription termination and antitermination
IXO1088_017255	COG0779	Required for maturation of 30S ribosomal subunits
IXO1088_017265	COG1007	ATP synthesis coupled electron transport
IXO1088_017295	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
IXO1088_017300	COG1034	ATP synthesis coupled electron transport
IXO1088_017305	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IXO1088_017310	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
IXO1088_017315	COG0649	NAD binding
IXO1088_017320	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IXO1088_017330	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IXO1088_017345	COG0149	triose-phosphate isomerase activity
IXO1088_017400	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IXO1088_017405	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IXO1088_017415	COG0159	tryptophan synthase activity
IXO1088_017425	COG0133	tryptophan synthase activity
IXO1088_017435	COG0135	phosphoribosylanthranilate isomerase activity
IXO1088_017440	COG0101	tRNA pseudouridine synthase activity
IXO1088_017460	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IXO1088_017465	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IXO1088_017470	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IXO1088_017475	COG2890	protein-(glutamine-N5) methyltransferase activity
IXO1088_017530	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IXO1088_017535	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IXO1088_017555	COG3039	Transposase
IXO1088_017715	COG3179	chitinase
IXO1088_017760	COG4695	Portal protein
IXO1088_017810	COG3039	Transposase
IXO1088_017820	COG0412	Dienelactone hydrolase
IXO1088_017840	COG0717	Belongs to the dCTP deaminase family
IXO1088_017845	COG0489	protein tyrosine kinase activity
IXO1088_017890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IXO1088_017895	COG2311	Membrane
IXO1088_017900	COG1047	Peptidyl-prolyl cis-trans
IXO1088_017905	COG0791	NLP P60 protein
IXO1088_017910	COG0791	NLP P60 protein
IXO1088_017930	COG1301	dicarboxylic acid transport
IXO1088_017935	COG1785	Belongs to the alkaline phosphatase family
IXO1088_017940	COG0037	tRNA processing
IXO1088_017945	COG1722	exodeoxyribonuclease VII activity
IXO1088_017950	COG0142	geranyltranstransferase activity
IXO1088_017975	COG0312	modulator of DNA gyrase
IXO1088_017980	COG3028	Belongs to the UPF0307 family
IXO1088_017985	COG0312	modulator of DNA gyrase
IXO1088_017995	COG3164	Protein of unknown function
IXO1088_018000	COG1530	ribonuclease E activity
IXO1088_018010	COG2968	Membrane
IXO1088_018015	COG3039	Transposase
IXO1088_018045	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IXO1088_018070	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IXO1088_018100	COG3118	belongs to the thioredoxin family
IXO1088_018165	COG3039	Transposase
IXO1088_018195	COG3039	Transposase
IXO1088_018230	COG3501	Rhs element vgr protein
IXO1088_018240	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IXO1088_018245	COG1845	cytochrome c oxidase, subunit III
IXO1088_018250	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IXO1088_018265	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IXO1088_018270	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IXO1088_018280	COG0196	riboflavin kinase activity
IXO1088_018285	COG0728	peptidoglycan biosynthetic process
IXO1088_018290	COG0268	Binds directly to 16S ribosomal RNA
IXO1088_018295	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IXO1088_018300	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IXO1088_018310	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IXO1088_018315	COG0824	Thioesterase
IXO1088_018330	COG1946	Acyl-CoA thioesterase
IXO1088_018340	COG1595	DNA-templated transcription, initiation
IXO1088_018355	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
IXO1088_018395	COG1877	trehalose-phosphatase activity
IXO1088_018400	COG3387	PFAM Glycoside hydrolase 15-related
IXO1088_018425	COG0564	pseudouridine synthase activity
IXO1088_018430	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IXO1088_018435	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IXO1088_018435	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IXO1088_018445	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IXO1088_018450	COG0045	succinate-CoA ligase (ADP-forming) activity
IXO1088_018490	COG2194	sulfuric ester hydrolase activity
IXO1088_018495	COG4969	Belongs to the N-Me-Phe pilin family
IXO1088_018505	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
IXO1088_018545	COG3209	COG3209 Rhs family protein
IXO1088_018560	COG3039	Transposase
IXO1088_018575	COG3039	Transposase
IXO1088_018610	COG1132	(ABC) transporter
IXO1088_018640	COG0745	RESPONSE REGULATOR receiver
IXO1088_018645	COG5002	protein histidine kinase activity
IXO1088_018645	COG5000	phosphorelay sensor kinase activity
IXO1088_018650	COG0475	glutathione-regulated potassium exporter activity
IXO1088_018660	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IXO1088_018680	COG1187	pseudouridine synthase activity
IXO1088_018685	COG5001	Diguanylate cyclase
IXO1088_018685	COG5002	protein histidine kinase activity
IXO1088_018810	COG1028	Short-chain dehydrogenase reductase Sdr
IXO1088_018830	COG0415	Belongs to the DNA photolyase family
IXO1088_018835	COG0305	Participates in initiation and elongation during chromosome replication
IXO1088_018845	COG0367	asparagine synthase
IXO1088_018885	COG0084	hydrolase, TatD family'
IXO1088_018890	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IXO1088_018950	COG0735	belongs to the Fur family
IXO1088_018955	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IXO1088_018980	COG3039	Transposase
IXO1088_019030	COG2205	protein histidine kinase activity
IXO1088_019050	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IXO1088_019060	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IXO1088_019075	COG0643	Histidine kinase
IXO1088_019075	COG2198	Histidine kinase
IXO1088_019085	COG0840	transmembrane signaling receptor activity
IXO1088_019090	COG0835	chemotaxis
IXO1088_019095	COG2202	Pas domain
IXO1088_019095	COG2200	EAL domain
IXO1088_019095	COG2199	diguanylate cyclase activity
IXO1088_019100	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IXO1088_019115	COG3590	peptidase
IXO1088_019130	COG0588	phosphoglycerate mutase activity
IXO1088_019135	COG1515	deoxyribonuclease V activity
IXO1088_019145	COG1741	Belongs to the pirin family
IXO1088_019185	COG3501	Rhs element vgr protein
IXO1088_019205	COG3501	Rhs element vgr protein
IXO1088_019210	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IXO1088_019260	COG3501	Rhs element vgr protein
IXO1088_019340	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IXO1088_019355	COG2197	response regulator
IXO1088_019360	COG4585	Histidine kinase
IXO1088_019380	COG2894	cell division
IXO1088_019385	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
IXO1088_019395	COG0642	Histidine kinase
IXO1088_019400	COG0745	RESPONSE REGULATOR receiver
IXO1088_019405	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IXO1088_019415	COG2194	sulfuric ester hydrolase activity
IXO1088_019445	COG3551	Protein conserved in bacteria
IXO1088_019510	COG0203	ribosomal protein L17
IXO1088_019520	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IXO1088_019525	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IXO1088_019535	COG0201	protein transport
IXO1088_019545	COG1841	ribosomal large subunit assembly
IXO1088_019575	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IXO1088_019585	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IXO1088_019590	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IXO1088_019595	COG0255	Belongs to the universal ribosomal protein uL29 family
IXO1088_019600	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IXO1088_019610	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IXO1088_019625	COG0089	rRNA binding
IXO1088_019630	COG0088	Forms part of the polypeptide exit tunnel
IXO1088_019635	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IXO1088_019640	COG0051	transcription antitermination factor activity, RNA binding
IXO1088_019660	COG0049	tRNA binding
IXO1088_019665	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IXO1088_019670	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IXO1088_019675	COG0085	RNA polymerase activity
IXO1088_019680	COG0222	ribosome binding
IXO1088_019685	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IXO1088_019695	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IXO1088_019705	COG0250	Participates in transcription elongation, termination and antitermination
IXO1088_019710	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IXO1088_019740	COG0012	GTP binding
IXO1088_019745	COG0193	aminoacyl-tRNA hydrolase activity
IXO1088_019755	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IXO1088_019770	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
IXO1088_019780	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IXO1088_019785	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IXO1088_019795	COG0521	Mo-molybdopterin cofactor biosynthetic process
IXO1088_019815	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IXO1088_019820	COG1295	ribonuclease BN
IXO1088_019850	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IXO1088_019855	COG1404	Belongs to the peptidase S8 family
IXO1088_019870	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IXO1088_019900	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
IXO1088_019925	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
IXO1088_019940	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IXO1088_019940	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IXO1088_019980	COG2890	protein-(glutamine-N5) methyltransferase activity
IXO1088_019990	COG3634	alkyl hydroperoxide reductase activity
IXO1088_019995	COG0583	DNA-binding transcription factor activity
IXO1088_020005	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IXO1088_020010	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IXO1088_020060	COG2197	response regulator
IXO1088_020175	COG3386	PFAM SMP-30 Gluconolaconase
IXO1088_020195	COG1024	Enoyl-CoA hydratase
IXO1088_020205	COG0318	PFAM AMP-dependent synthetase and ligase
IXO1088_020210	COG0583	DNA-binding transcription factor activity
IXO1088_020250	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IXO1088_020255	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IXO1088_020265	COG2096	Adenosyltransferase
IXO1088_020270	COG0123	including yeast histone deacetylase and acetoin utilization protein
IXO1088_020285	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IXO1088_020295	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IXO1088_020300	COG2967	ApaG domain
IXO1088_020305	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IXO1088_020330	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IXO1088_020350	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IXO1088_020375	COG0642	Histidine kinase
IXO1088_020390	COG4181	ATPase activity
IXO1088_020400	COG2175	clavaminate synthase activity
IXO1088_020450	COG0667	Aldo Keto reductase
IXO1088_020460	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IXO1088_020465	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IXO1088_020480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IXO1088_020495	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IXO1088_020535	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IXO1088_020540	COG2226	methyltransferase
IXO1088_020595	COG3321	synthase
IXO1088_020595	COG0604	alcohol dehydrogenase
IXO1088_020595	COG1028	Short-chain dehydrogenase reductase Sdr
IXO1088_020610	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IXO1088_020625	COG0494	nUDIX hydrolase
IXO1088_020635	COG0653	protein targeting
IXO1088_020640	COG4942	peptidase
IXO1088_020640	COG1388	LysM domain
IXO1088_020650	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
IXO1088_020665	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IXO1088_020670	COG1181	Belongs to the D-alanine--D-alanine ligase family
IXO1088_020675	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IXO1088_020690	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IXO1088_020695	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IXO1088_020710	COG3116	cell division
IXO1088_020715	COG0275	rRNA processing
IXO1088_020750	COG0792	nuclease activity
IXO1088_020755	COG1988	membrane-bound metal-dependent
IXO1088_020760	COG0277	FAD linked oxidase domain protein
IXO1088_020765	COG0745	RESPONSE REGULATOR receiver
IXO1088_020770	COG2205	protein histidine kinase activity
IXO1088_020780	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
IXO1088_020785	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IXO1088_020810	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IXO1088_020815	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IXO1088_020820	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
IXO1088_020840	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IXO1088_020840	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IXO1088_020860	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IXO1088_020880	COG0488	(ABC) transporter
IXO1088_020930	COG0745	RESPONSE REGULATOR receiver
IXO1088_020935	COG2205	protein histidine kinase activity
IXO1088_020970	COG2205	protein histidine kinase activity
IXO1088_020985	COG0218	Necessary for normal cell division and for the maintenance of normal septation
IXO1088_021120	COG0726	polysaccharide deacetylase
IXO1088_021120	COG1649	PFAM Uncharacterised BCR, COG1649
IXO1088_021125	COG1215	transferase activity, transferring glycosyl groups
IXO1088_021135	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IXO1088_021140	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IXO1088_021145	COG1609	Transcriptional regulator
IXO1088_021155	COG2188	Transcriptional regulator
IXO1088_021170	COG3250	beta-galactosidase activity
IXO1088_021220	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IXO1088_021225	COG4191	Histidine kinase
IXO1088_021230	COG0784	Response regulator, receiver
IXO1088_021235	COG4251	negative regulation of phosphorylation
IXO1088_021240	COG2823	Periplasmic or secreted lipoprotein
IXO1088_021245	COG0673	inositol 2-dehydrogenase activity
IXO1088_021250	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
IXO1088_021285	COG1051	belongs to the nudix hydrolase family
IXO1088_021285	COG1056	cytidyltransferase-related domain
IXO1088_021310	COG2921	Belongs to the UPF0250 family
IXO1088_021325	COG1686	Belongs to the peptidase S11 family
IXO1088_021330	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IXO1088_021335	COG2951	lytic endotransglycosylase activity
IXO1088_021355	COG0772	Belongs to the SEDS family
IXO1088_021370	COG1792	Involved in formation and maintenance of cell shape
IXO1088_021375	COG1077	Cell shape determining protein MreB Mrl
IXO1088_021380	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IXO1088_021425	COG2199	diguanylate cyclase activity
IXO1088_021430	COG0308	aminopeptidase N
IXO1088_021460	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IXO1088_021505	COG1505	serine-type exopeptidase activity
IXO1088_021530	COG0181	hydroxymethylbilane synthase activity
IXO1088_021540	COG3275	phosphorelay sensor kinase activity
IXO1088_021595	COG0659	secondary active sulfate transmembrane transporter activity
IXO1088_021600	COG5297	Belongs to the glycosyl hydrolase family 6
IXO1088_021600	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IXO1088_021610	COG0840	transmembrane signaling receptor activity
IXO1088_021670	COG3039	Transposase
IXO1088_021690	COG0598	Magnesium transport protein CorA
IXO1088_021700	COG1113	amino acid transport
IXO1088_021710	COG5297	Belongs to the glycosyl hydrolase family 6
IXO1088_021715	COG4305	rare lipoprotein A
IXO1088_021720	COG0697	spore germination
IXO1088_021780	COG4221	oxidoreductase activity
IXO1088_021810	COG0456	acetyltransferase
IXO1088_021820	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IXO1088_021865	COG2111	Na H antiporter
IXO1088_021865	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IXO1088_021870	COG1006	Multisubunit Na H antiporter MnhC subunit
IXO1088_021875	COG0651	ATP synthesis coupled electron transport
IXO1088_021885	COG2212	antiporter activity
IXO1088_021890	COG1320	monovalent cation:proton antiporter activity
IXO1088_021910	COG3039	Transposase
IXO1088_021915	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
IXO1088_021935	COG3104	oligopeptide transport
IXO1088_021940	COG3483	tryptophan 2,3-dioxygenase activity
IXO1088_021950	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IXO1088_021985	COG0183	Belongs to the thiolase family
IXO1088_022060	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
IXO1088_022065	COG3023	N-Acetylmuramoyl-L-alanine amidase
IXO1088_022075	COG4948	Mandelate Racemase Muconate Lactonizing
IXO1088_022105	COG0531	amino acid
IXO1088_022130	COG4682	membrane
IXO1088_022135	COG2133	pyrroloquinoline quinone binding
IXO1088_022195	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IXO1088_022200	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IXO1088_022210	COG1610	YqeY-like protein
IXO1088_022230	COG1295	ribonuclease BN
IXO1088_022235	COG0358	DNA primase activity
IXO1088_022280	COG3039	Transposase
IXO1088_022430	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IXO1088_022440	COG1560	Kdo2-lipid A biosynthetic process
IXO1088_022490	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IXO1088_022490	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IXO1088_022495	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IXO1088_022500	COG0242	peptide deformylase activity
IXO1088_022505	COG1652	LysM domain
IXO1088_022510	COG0758	DNA mediated transformation
IXO1088_022515	COG2922	Belongs to the Smg family
IXO1088_022530	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IXO1088_022530	COG1754	DNA topoisomerase type I activity
IXO1088_022535	COG0009	L-threonylcarbamoyladenylate synthase
IXO1088_022550	COG1028	Short-chain dehydrogenase reductase Sdr
IXO1088_022560	COG0616	signal peptide processing
IXO1088_022565	COG0534	Mate efflux family protein
IXO1088_022590	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IXO1088_022625	COG1324	tolerance protein
IXO1088_022645	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
IXO1088_022650	COG0511	ligase activity, forming carbon-carbon bonds
IXO1088_022660	COG0439	Biotin carboxylase
IXO1088_022720	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
IXO1088_022790	COG3210	domain, Protein
IXO1088_022830	COG3210	domain, Protein
IXO1088_022835	COG2831	hemolysin activation secretion protein
IXO1088_022865	COG2267	carboxylic ester hydrolase activity
IXO1088_022875	COG2267	carboxylic ester hydrolase activity
IXO1088_022890	COG0419	ATPase involved in DNA repair
IXO1088_022900	COG0151	Belongs to the GarS family
IXO1088_022920	COG1289	transmembrane transporter activity
IXO1088_022935	COG2814	Major facilitator Superfamily
IXO1088_022960	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
IXO1088_022995	COG0745	RESPONSE REGULATOR receiver
IXO1088_023045	COG0739	heme binding
IXO1088_023065	COG2211	Major facilitator Superfamily
IXO1088_023070	COG0708	Exodeoxyribonuclease III
IXO1088_023085	COG1192	Involved in chromosome partitioning
IXO1088_023090	COG1475	DNA binding
IXO1088_023105	COG0463	Glycosyl transferase, family 2
IXO1088_023130	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IXO1088_023155	COG4221	oxidoreductase activity
IXO1088_023180	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IXO1088_023185	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IXO1088_023200	COG3485	protocatechuate 3,4-dioxygenase
IXO1088_023205	COG3485	protocatechuate 3,4-dioxygenase
IXO1088_023245	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IXO1088_023255	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IXO1088_023270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IXO1088_023270	COG1042	CoA-binding domain protein
IXO1088_023270	COG0045	succinate-CoA ligase (ADP-forming) activity
IXO1088_023280	COG2239	Acts as a magnesium transporter
IXO1088_023295	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IXO1088_023315	COG3100	YcgL domain-containing protein
IXO1088_023320	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IXO1088_023330	COG0463	Glycosyl transferase, family 2
IXO1088_023345	COG1028	Short-chain dehydrogenase reductase Sdr
IXO1088_023360	COG0156	8-amino-7-oxononanoate synthase activity
IXO1088_023365	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IXO1088_023370	COG1040	competence protein
IXO1088_023375	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IXO1088_023390	COG0582	viral genome integration into host DNA
IXO1088_023450	COG0464	growth
IXO1088_023470	COG0628	permease
IXO1088_023480	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IXO1088_023490	COG1595	DNA-templated transcription, initiation
IXO1088_023495	COG0753	catalase activity
IXO1088_023550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IXO1088_023555	COG0180	Tryptophanyl-tRNA synthetase
IXO1088_023560	COG3237	CsbD-like
IXO1088_023600	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IXO1088_023615	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IXO1088_023620	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
IXO1088_023620	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
IXO1088_023645	COG2205	protein histidine kinase activity
IXO1088_023650	COG0745	RESPONSE REGULATOR receiver
IXO1088_023660	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IXO1088_023690	COG1566	PFAM secretion protein HlyD family protein
IXO1088_023710	COG1199	ATP-dependent helicase activity
IXO1088_023745	COG0583	DNA-binding transcription factor activity
IXO1088_023795	COG0625	glutathione transferase activity
IXO1088_023830	COG4555	ABC transporter
IXO1088_023840	COG1476	TRANSCRIPTIONal
IXO1088_023865	COG1131	(ABC) transporter
IXO1088_023870	COG0842	Transport permease protein
IXO1088_023970	COG1181	Belongs to the D-alanine--D-alanine ligase family
IXO1088_023985	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IXO1088_023995	COG0564	pseudouridine synthase activity
IXO1088_024025	COG0339	signal peptide processing
IXO1088_024055	COG3254	rhamnose metabolic process
IXO1088_024060	COG0738	Major facilitator superfamily
IXO1088_024065	COG1414	Transcriptional regulator
IXO1088_024080	COG2205	protein histidine kinase activity
IXO1088_024090	COG3459	Glycosyltransferase 36 associated
IXO1088_024095	COG2211	Major facilitator Superfamily
IXO1088_024100	COG3265	gluconokinase activity
IXO1088_024110	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IXO1088_024150	COG3039	Transposase
IXO1088_024215	COG1127	ABC transporter
IXO1088_024220	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IXO1088_024225	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IXO1088_024240	COG2853	Lipoprotein
IXO1088_024270	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IXO1088_024340	COG0676	glucose-6-phosphate 1-epimerase activity
IXO1088_024365	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IXO1088_024375	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IXO1088_024385	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IXO1088_024395	COG1064	alcohol dehydrogenase
IXO1088_024445	COG1522	sequence-specific DNA binding
IXO1088_024450	COG3186	Phenylalanine-4-hydroxylase
IXO1088_024465	COG2755	lipolytic protein G-D-S-L family
IXO1088_024490	COG0656	L-ascorbic acid biosynthetic process
IXO1088_024495	COG2130	NADP-dependent
IXO1088_024500	COG0667	Aldo Keto reductase
IXO1088_024510	COG1187	pseudouridine synthase activity
IXO1088_024525	COG1643	Atp-dependent helicase
IXO1088_024530	COG4807	Protein conserved in bacteria
IXO1088_024535	COG4948	Mandelate Racemase Muconate Lactonizing
IXO1088_024545	COG0179	Fumarylacetoacetate (FAA) hydrolase
IXO1088_024550	COG1028	Short-chain dehydrogenase reductase Sdr
IXO1088_024570	COG3507	Belongs to the glycosyl hydrolase 43 family
IXO1088_024610	COG3162	membrane
IXO1088_024615	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IXO1088_024630	COG0708	Exodeoxyribonuclease III
IXO1088_024645	COG2091	lysine biosynthetic process via aminoadipic acid
IXO1088_024655	COG3540	Alkaline phosphatase
IXO1088_024660	COG0357	Ribosomal RNA small subunit methyltransferase G
IXO1088_024685	COG2159	amidohydrolase
IXO1088_024705	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IXO1088_024710	COG0583	DNA-binding transcription factor activity
IXO1088_024715	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IXO1088_024735	COG0210	DNA helicase
IXO1088_024750	COG0531	amino acid
IXO1088_024765	COG1322	Protein conserved in bacteria
IXO1088_024775	COG0386	Belongs to the glutathione peroxidase family
IXO1088_024830	COG0793	Belongs to the peptidase S41A family
IXO1088_024835	COG4942	peptidase
IXO1088_024845	COG2234	aminopeptidase activity
IXO1088_024895	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IXO1088_024900	COG0302	gtp cyclohydrolase
IXO1088_024930	COG0477	Major facilitator Superfamily
IXO1088_025015	COG1192	Involved in chromosome partitioning
IXO1088_025050	COG1929	Belongs to the glycerate kinase type-1 family
IXO1088_025055	COG2271	Major facilitator Superfamily
IXO1088_025070	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IXO1088_025080	COG0861	Integral membrane protein TerC family
IXO1088_025090	COG0584	glycerophosphoryl diester phosphodiesterase
IXO1088_025100	COG0671	phosphoesterase, PA-phosphatase related
IXO1088_025110	COG0726	polysaccharide deacetylase
IXO1088_025115	COG0706	membrane insertase activity