locus-tag	class	description
IXO1104_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IXO1104_00020	COG0187	DNA topoisomerase II activity
IXO1104_00030	COG0501	Belongs to the peptidase M48B family
IXO1104_00060	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IXO1104_00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IXO1104_00080	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
IXO1104_00090	COG4772	TonB-dependent receptor
IXO1104_00105	COG3039	Transposase
IXO1104_00110	COG1304	FMN binding
IXO1104_00130	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IXO1104_00140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IXO1104_00230	COG2826	transposase and inactivated derivatives, IS30 family
IXO1104_00255	COG3039	Transposase
IXO1104_00265	COG1090	epimerase
IXO1104_00275	COG0642	Histidine kinase
IXO1104_00285	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IXO1104_00390	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IXO1104_00465	COG1511	domain protein
IXO1104_00465	COG3264	Mechanosensitive ion channel
IXO1104_00480	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IXO1104_00485	COG2354	Protein conserved in bacteria
IXO1104_00490	COG1649	PFAM Uncharacterised BCR, COG1649
IXO1104_00500	COG0297	glycogen (starch) synthase activity
IXO1104_00510	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IXO1104_00535	COG0702	epimerase
IXO1104_00550	COG1858	cytochrome C peroxidase
IXO1104_00615	COG0513	Belongs to the DEAD box helicase family
IXO1104_00625	COG3039	Transposase
IXO1104_00670	COG1272	protein, Hemolysin III
IXO1104_00675	COG1205	dead DEAH box helicase
IXO1104_00675	COG1111	helicase
IXO1104_00735	COG0067	glutamate synthase
IXO1104_00735	COG0070	glutamate synthase
IXO1104_00735	COG0069	glutamate synthase activity
IXO1104_00740	COG0493	'glutamate synthase
IXO1104_00780	COG1609	Transcriptional regulator
IXO1104_00810	COG0366	Alpha amylase catalytic
IXO1104_00815	COG0366	Alpha amylase catalytic
IXO1104_00840	COG3039	Transposase
IXO1104_00870	COG0606	chelatase, subunit chli
IXO1104_00915	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IXO1104_00920	COG1166	arginine decarboxylase activity
IXO1104_00965	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IXO1104_00990	COG1028	Short-chain dehydrogenase reductase Sdr
IXO1104_01015	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
IXO1104_01030	COG0210	DNA helicase
IXO1104_01045	COG3132	Protein of unknown function, DUF480
IXO1104_01050	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
IXO1104_01055	COG0284	orotidine-5'-phosphate decarboxylase activity
IXO1104_01090	COG2937	Belongs to the GPAT DAPAT family
IXO1104_01130	COG1752	Esterase of the alpha-beta hydrolase superfamily
IXO1104_01140	COG1119	ATPase activity
IXO1104_01155	COG1125	glycine betaine transport
IXO1104_01155	COG0517	IMP dehydrogenase activity
IXO1104_01170	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IXO1104_01175	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
IXO1104_01180	COG3550	peptidyl-serine autophosphorylation
IXO1104_01185	COG1396	sequence-specific DNA binding
IXO1104_01210	COG0489	protein tyrosine kinase activity
IXO1104_01215	COG2062	phosphohistidine phosphatase, SixA
IXO1104_01225	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IXO1104_01270	COG1968	undecaprenyl-diphosphatase activity
IXO1104_01275	COG0174	glutamine synthetase
IXO1104_01280	COG0347	Belongs to the P(II) protein family
IXO1104_01285	COG0004	ammonium transporteR
IXO1104_01290	COG3852	Histidine kinase
IXO1104_01295	COG2204	response regulator
IXO1104_01300	COG2032	superoxide dismutase activity
IXO1104_01305	COG2032	superoxide dismutase activity
IXO1104_01370	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IXO1104_01375	COG1074	ATP-dependent DNA helicase activity
IXO1104_01385	COG3549	Plasmid maintenance system killer
IXO1104_01465	COG1764	response to oxidative stress
IXO1104_01470	COG1846	Transcriptional regulator
IXO1104_01515	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IXO1104_01555	COG2211	Major facilitator Superfamily
IXO1104_01575	COG3693	PFAM glycoside hydrolase, family 10
IXO1104_01600	COG0246	Mannitol dehydrogenase
IXO1104_01605	COG1472	Belongs to the glycosyl hydrolase 3 family
IXO1104_01615	COG4948	Mandelate Racemase Muconate Lactonizing
IXO1104_01625	COG3661	Belongs to the glycosyl hydrolase 67 family
IXO1104_01640	COG0037	tRNA processing
IXO1104_01645	COG2974	May be involved in recombination
IXO1104_01670	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
IXO1104_01680	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IXO1104_01690	COG0805	protein transport
IXO1104_01700	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IXO1104_01700	COG0519	Catalyzes the synthesis of GMP from XMP
IXO1104_01715	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IXO1104_01720	COG0752	glycyl-tRNA synthetase alpha subunit
IXO1104_01730	COG0457	Tetratricopeptide repeat
IXO1104_01735	COG4771	TonB-dependent receptor
IXO1104_01750	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IXO1104_01760	COG0697	spore germination
IXO1104_01770	COG0523	cobalamin synthesis protein
IXO1104_01820	COG1960	acyl-CoA dehydrogenase activity
IXO1104_01825	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IXO1104_01830	COG4770	biotin carboxylase activity
IXO1104_01875	COG2072	flavoprotein involved in K transport
IXO1104_01895	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IXO1104_01940	COG0084	hydrolase, TatD family'
IXO1104_01955	COG0583	DNA-binding transcription factor activity
IXO1104_01960	COG2814	Major facilitator Superfamily
IXO1104_01970	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IXO1104_01975	COG1902	pentaerythritol trinitrate reductase activity
IXO1104_02005	COG0745	RESPONSE REGULATOR receiver
IXO1104_02025	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IXO1104_02030	COG0583	DNA-binding transcription factor activity
IXO1104_02060	COG0702	epimerase
IXO1104_02065	COG1733	regulation of RNA biosynthetic process
IXO1104_02120	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IXO1104_02135	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IXO1104_02170	COG2911	Protein conserved in bacteria
IXO1104_02175	COG0729	surface antigen
IXO1104_02190	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IXO1104_02195	COG3118	belongs to the thioredoxin family
IXO1104_02205	COG2884	Cell division ATP-binding protein ftsE
IXO1104_02210	COG2177	Part of the ABC transporter FtsEX involved in
IXO1104_02215	COG3437	response regulator, receiver
IXO1104_02220	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IXO1104_02225	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IXO1104_02235	COG1252	NADH dehydrogenase
IXO1104_02260	COG0459	protein refolding
IXO1104_02270	COG4771	TonB-dependent receptor
IXO1104_02285	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IXO1104_02330	COG3386	PFAM SMP-30 Gluconolaconase
IXO1104_02345	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IXO1104_02370	COG0778	Nitroreductase
IXO1104_02375	COG2353	YceI-like domain
IXO1104_02465	COG0408	coproporphyrinogen oxidase activity
IXO1104_02475	COG3039	Transposase
IXO1104_02500	COG0129	dihydroxy-acid dehydratase activity
IXO1104_02510	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IXO1104_02540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IXO1104_02545	COG0318	PFAM AMP-dependent synthetase and ligase
IXO1104_02550	COG0727	PFAM Uncharacterised protein family (UPF0153)
IXO1104_02555	COG0596	Alpha beta hydrolase
IXO1104_02570	COG2189	Belongs to the N(4) N(6)-methyltransferase family
IXO1104_02575	COG3177	Filamentation induced by cAMP protein fic
IXO1104_02580	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IXO1104_02595	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IXO1104_02620	COG4191	Histidine kinase
IXO1104_02640	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
IXO1104_02645	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IXO1104_02675	COG5383	Protein conserved in bacteria
IXO1104_02690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IXO1104_02695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IXO1104_02700	COG1473	amidohydrolase
IXO1104_02710	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IXO1104_02710	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IXO1104_02735	COG3039	Transposase
IXO1104_02795	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IXO1104_02810	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IXO1104_02815	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
IXO1104_02825	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
IXO1104_02830	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IXO1104_02835	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IXO1104_02885	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IXO1104_02900	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
IXO1104_02970	COG3039	Transposase
IXO1104_02990	COG1294	oxidase, subunit
IXO1104_02995	COG1271	oxidase subunit
IXO1104_03045	COG2972	Histidine kinase
IXO1104_03060	COG0531	amino acid
IXO1104_03080	COG3590	peptidase
IXO1104_03090	COG0667	Aldo Keto reductase
IXO1104_03105	COG3384	dioxygenase
IXO1104_03115	COG1573	uracil-dna glycosylase
IXO1104_03125	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
IXO1104_03135	COG0025	NhaP-type Na H and K H
IXO1104_03140	COG1131	(ABC) transporter
IXO1104_03145	COG0842	Transport permease protein
IXO1104_03160	COG1404	Belongs to the peptidase S8 family
IXO1104_03175	COG0745	RESPONSE REGULATOR receiver
IXO1104_03225	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IXO1104_03250	COG2202	Pas domain
IXO1104_03250	COG2205	protein histidine kinase activity
IXO1104_03280	COG2813	Specifically methylates the guanine in position
IXO1104_03285	COG1187	pseudouridine synthase activity
IXO1104_03290	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IXO1104_03325	COG0697	spore germination
IXO1104_03335	COG2011	ABC-type metal ion transport system permease component
IXO1104_03365	COG0508	dehydrogenase complex catalyzes the overall conversion of
IXO1104_03375	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IXO1104_03395	COG0356	it plays a direct role in the translocation of protons across the membrane
IXO1104_03405	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IXO1104_03415	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IXO1104_03420	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IXO1104_03425	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IXO1104_03430	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IXO1104_03480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IXO1104_03485	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IXO1104_03535	COG0339	signal peptide processing
IXO1104_03575	COG1956	GAF domain-containing protein
IXO1104_03580	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IXO1104_03590	COG0720	synthase
IXO1104_03595	COG0513	Belongs to the DEAD box helicase family
IXO1104_03610	COG0625	glutathione transferase activity
IXO1104_03640	COG0626	cystathionine gamma-synthase activity
IXO1104_03685	COG3328	transposase activity
IXO1104_03710	COG2086	electron transfer activity
IXO1104_03735	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
IXO1104_03735	COG0662	Cupin 2, conserved barrel domain protein
IXO1104_03740	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IXO1104_03775	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IXO1104_03775	COG3218	ABC-type transport auxiliary lipoprotein component
IXO1104_03780	COG1127	ABC transporter
IXO1104_03785	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IXO1104_03800	COG0442	prolyl-tRNA aminoacylation
IXO1104_03810	COG1183	phosphatidylcholine synthase activity
IXO1104_03840	COG3039	Transposase
IXO1104_03865	COG3039	Transposase
IXO1104_03895	COG0525	valine-tRNA ligase activity
IXO1104_03910	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IXO1104_03920	COG0795	lipopolysaccharide-transporting ATPase activity
IXO1104_03935	COG4974	Belongs to the 'phage' integrase family
IXO1104_03940	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IXO1104_03945	COG0047	phosphoribosylformylglycinamidine synthase activity
IXO1104_03945	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IXO1104_03950	COG5295	Hep Hag repeat protein
IXO1104_03960	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IXO1104_03970	COG1459	type II secretion system
IXO1104_03975	COG2165	general secretion pathway protein
IXO1104_03980	COG4970	Tfp pilus assembly protein FimT
IXO1104_03985	COG2165	general secretion pathway protein
IXO1104_03990	COG4795	General secretion pathway protein
IXO1104_03995	COG3156	type II secretion system protein K
IXO1104_04000	COG3166	PFAM Fimbrial assembly family protein
IXO1104_04015	COG1450	Type ii and iii secretion system protein
IXO1104_04025	COG2188	Transcriptional regulator
IXO1104_04075	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IXO1104_04080	COG1518	maintenance of DNA repeat elements
IXO1104_04125	COG1399	metal-binding, possibly nucleic acid-binding protein
IXO1104_04150	COG1028	Short-chain dehydrogenase reductase Sdr
IXO1104_04155	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IXO1104_04165	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IXO1104_04170	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IXO1104_04205	COG3829	transcription factor binding
IXO1104_04300	COG2826	transposase and inactivated derivatives, IS30 family
IXO1104_04310	COG0678	peroxiredoxin activity
IXO1104_04330	COG0330	HflC and HflK could
IXO1104_04335	COG0330	HflC and HflK could
IXO1104_04345	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IXO1104_04350	COG0308	aminopeptidase N
IXO1104_04395	COG1560	Kdo2-lipid A biosynthetic process
IXO1104_04400	COG1519	Transferase
IXO1104_04405	COG1538	Outer membrane efflux protein
IXO1104_04410	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IXO1104_04440	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IXO1104_04445	COG0066	3-isopropylmalate dehydratase activity
IXO1104_04480	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IXO1104_04490	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IXO1104_04495	COG3710	Transcriptional regulator
IXO1104_04520	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IXO1104_04530	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
IXO1104_04540	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
IXO1104_04570	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IXO1104_04580	COG3781	membrane
IXO1104_04735	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
IXO1104_04755	COG1217	gtp-binding protein TYPA
IXO1104_04760	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IXO1104_04795	COG3039	Transposase
IXO1104_04815	COG0584	glycerophosphoryl diester phosphodiesterase
IXO1104_04845	COG1902	pentaerythritol trinitrate reductase activity
IXO1104_04845	COG0446	pyridine nucleotide-disulphide oxidoreductase
IXO1104_04850	COG0604	alcohol dehydrogenase
IXO1104_04875	COG0156	8-amino-7-oxononanoate synthase activity
IXO1104_04880	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IXO1104_04885	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IXO1104_04890	COG4208	sulfate ABC transporter
IXO1104_04895	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IXO1104_04925	COG0588	phosphoglycerate mutase activity
IXO1104_04935	COG0285	dihydrofolate synthase activity
IXO1104_04955	COG2833	Protein of unknown function (DUF455)
IXO1104_04975	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IXO1104_04980	COG0671	phosphoesterase, PA-phosphatase related
IXO1104_04985	COG0438	transferase activity, transferring glycosyl groups
IXO1104_04995	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IXO1104_05010	COG4783	chaperone-mediated protein folding
IXO1104_05035	COG0473	3-isopropylmalate dehydrogenase activity
IXO1104_05085	COG0544	peptidyl-prolyl cis-trans isomerase activity
IXO1104_05125	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IXO1104_05150	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IXO1104_05160	COG0631	protein serine/threonine phosphatase activity
IXO1104_05210	COG0582	viral genome integration into host DNA
IXO1104_05220	COG0859	PFAM glycosyl transferase family 9
IXO1104_05225	COG3642	lipopolysaccharide core region biosynthetic process
IXO1104_05230	COG1234	tRNA 3'-trailer cleavage
IXO1104_05235	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IXO1104_05245	COG0315	cyclic pyranopterin monophosphate synthase activity
IXO1104_05250	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IXO1104_05255	COG0314	molybdopterin synthase activity
IXO1104_05285	COG0537	adenosine 5'-monophosphoramidase activity
IXO1104_05305	COG0714	Associated with various cellular activities
IXO1104_05325	COG0242	peptide deformylase activity
IXO1104_05370	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IXO1104_05375	COG0726	polysaccharide deacetylase
IXO1104_05400	COG1162	GTPase activity
IXO1104_05435	COG1609	Transcriptional regulator
IXO1104_05440	COG1028	Short-chain dehydrogenase reductase Sdr
IXO1104_05445	COG2851	Citrate transporter
IXO1104_05460	COG0642	Histidine kinase
IXO1104_05470	COG2197	response regulator
IXO1104_05485	COG0583	DNA-binding transcription factor activity
IXO1104_05500	COG4191	Histidine kinase
IXO1104_05520	COG0280	phosphate acetyltransferase
IXO1104_05520	COG0281	malic enzyme
IXO1104_05580	COG0352	thiamine-phosphate diphosphorylase activity
IXO1104_05585	COG1773	rubredoxin
IXO1104_05590	COG2912	Transglutaminase-like superfamily
IXO1104_05600	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IXO1104_05610	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IXO1104_05635	COG0006	proline dipeptidase activity
IXO1104_05665	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IXO1104_05675	COG0346	lactoylglutathione lyase activity
IXO1104_05680	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IXO1104_05685	COG1561	YicC-like family, N-terminal region
IXO1104_05710	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IXO1104_05720	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IXO1104_05745	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
IXO1104_05785	COG0714	Associated with various cellular activities
IXO1104_05805	COG2304	oxidoreductase activity
IXO1104_05825	COG1301	dicarboxylic acid transport
IXO1104_05830	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IXO1104_05840	COG0739	heme binding
IXO1104_05845	COG1376	ErfK ybiS ycfS ynhG family protein
IXO1104_05870	COG1022	Amp-dependent synthetase and ligase
IXO1104_05880	COG1028	Short-chain dehydrogenase reductase Sdr
IXO1104_05895	COG0642	Histidine kinase
IXO1104_05915	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IXO1104_05920	COG4149	molybdate abc transporter
IXO1104_05925	COG0725	ABC transporter, periplasmic molybdate-binding protein
IXO1104_05930	COG3453	Protein conserved in bacteria
IXO1104_05930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IXO1104_05970	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IXO1104_05990	COG2205	protein histidine kinase activity
IXO1104_05995	COG0745	RESPONSE REGULATOR receiver
IXO1104_06015	COG3039	Transposase
IXO1104_06050	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IXO1104_06055	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IXO1104_06110	COG3039	Transposase
IXO1104_06115	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IXO1104_06145	COG2201	protein-glutamate methylesterase activity
IXO1104_06225	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IXO1104_06235	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IXO1104_06240	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IXO1104_06255	COG1842	Phage shock protein A
IXO1104_06280	COG0754	glutathionylspermidine amidase activity
IXO1104_06340	COG0531	amino acid
IXO1104_06345	COG2197	response regulator
IXO1104_06360	COG1113	amino acid transport
IXO1104_06380	COG1271	oxidase subunit
IXO1104_06385	COG1294	oxidase, subunit
IXO1104_06395	COG2239	Acts as a magnesium transporter
IXO1104_06400	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IXO1104_06405	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IXO1104_06415	COG1660	Displays ATPase and GTPase activities
IXO1104_06420	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IXO1104_06425	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IXO1104_06440	COG1137	ATPase activity
IXO1104_06445	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IXO1104_06455	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IXO1104_06465	COG0271	Belongs to the BolA IbaG family
IXO1104_06470	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IXO1104_06490	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IXO1104_06505	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IXO1104_06515	COG0628	permease
IXO1104_06525	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IXO1104_06530	COG3178	'Phosphotransferase
IXO1104_06545	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IXO1104_06550	COG1555	photosystem II stabilization
IXO1104_06565	COG3039	Transposase
IXO1104_06605	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IXO1104_06615	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IXO1104_06640	COG0228	four-way junction DNA binding
IXO1104_06645	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IXO1104_06650	COG0336	Belongs to the RNA methyltransferase TrmD family
IXO1104_06665	COG0534	Mate efflux family protein
IXO1104_06700	COG0542	response to heat
IXO1104_06735	COG4206	TonB-dependent receptor
IXO1104_06800	COG0019	diaminopimelate decarboxylase activity
IXO1104_06810	COG2814	Major facilitator Superfamily
IXO1104_06815	COG4264	IucA IucC family
IXO1104_06825	COG4772	TonB-dependent receptor
IXO1104_06840	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IXO1104_06840	COG4651	solute:proton antiporter activity
IXO1104_06860	COG0488	(ABC) transporter
IXO1104_06885	COG2755	lipolytic protein G-D-S-L family
IXO1104_06885	COG0657	acetylesterase activity
IXO1104_06905	COG2207	Transcriptional regulator
IXO1104_06910	COG0326	Molecular chaperone. Has ATPase activity
IXO1104_06935	COG3328	transposase activity
IXO1104_06940	COG0174	glutamine synthetase
IXO1104_06945	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
IXO1104_06955	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IXO1104_06970	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IXO1104_07005	COG2146	nitrite reductase [NAD(P)H] activity
IXO1104_07015	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IXO1104_07020	COG0719	Fe-S assembly protein
IXO1104_07025	COG0396	ATPase activity
IXO1104_07030	COG0719	Fe-S assembly protein
IXO1104_07035	COG1959	2 iron, 2 sulfur cluster binding
IXO1104_07055	COG0693	protein deglycase activity
IXO1104_07095	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IXO1104_07125	COG0519	Catalyzes the synthesis of GMP from XMP
IXO1104_07135	COG1678	Uncharacterized ACR, COG1678
IXO1104_07140	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IXO1104_07155	COG1764	response to oxidative stress
IXO1104_07165	COG0384	phenazine biosynthesis protein PhzF
IXO1104_07175	COG0527	aspartate kinase activity
IXO1104_07200	COG0142	geranyltranstransferase activity
IXO1104_07205	COG0629	single-stranded DNA binding
IXO1104_07260	COG2879	small protein
IXO1104_07265	COG1966	Carbon starvation protein
IXO1104_07270	COG1741	Belongs to the pirin family
IXO1104_07325	COG3179	chitinase
IXO1104_07340	COG3328	transposase activity
IXO1104_07355	COG3179	chitinase
IXO1104_07540	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
IXO1104_07550	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
IXO1104_07585	COG0732	type I restriction modification DNA specificity domain
IXO1104_07670	COG0587	DNA-directed DNA polymerase activity
IXO1104_07685	COG1297	OPT oligopeptide transporter protein
IXO1104_07705	COG1506	peptidase
IXO1104_07705	COG0823	Involved in the tonB-independent uptake of proteins
IXO1104_07725	COG1917	Cupin 2, conserved barrel domain protein
IXO1104_07725	COG2207	Transcriptional regulator
IXO1104_07750	COG0753	catalase activity
IXO1104_07780	COG0126	phosphoglycerate kinase activity
IXO1104_07790	COG0469	pyruvate kinase activity
IXO1104_07795	COG3588	fructose-bisphosphate aldolase
IXO1104_07800	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
IXO1104_07845	COG0784	Response regulator, receiver
IXO1104_07845	COG2198	Histidine kinase
IXO1104_07845	COG2205	protein histidine kinase activity
IXO1104_07865	COG0175	sulfate reduction
IXO1104_07870	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IXO1104_07875	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IXO1104_07880	COG0175	sulfate reduction
IXO1104_07885	COG0529	Catalyzes the synthesis of activated sulfate
IXO1104_07885	COG2895	sulfate adenylyltransferase (ATP) activity
IXO1104_07895	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IXO1104_07900	COG0308	aminopeptidase N
IXO1104_07925	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IXO1104_07950	COG1970	mechanosensitive ion channel activity
IXO1104_07980	COG3273	potassium ion transport
IXO1104_07980	COG0471	metal ion transport
IXO1104_07990	COG2022	thiamine diphosphate biosynthetic process
IXO1104_08155	COG0632	four-way junction helicase activity
IXO1104_08165	COG2255	four-way junction helicase activity
IXO1104_08170	COG0824	Thioesterase
IXO1104_08180	COG0848	biopolymer transport protein
IXO1104_08195	COG2885	chlorophyll binding
IXO1104_08205	COG0602	queuosine metabolic process
IXO1104_08230	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IXO1104_08255	COG0514	ATP-dependent DNA helicase (RecQ)
IXO1104_08260	COG0783	Belongs to the Dps family
IXO1104_08265	COG1643	Atp-dependent helicase
IXO1104_08290	COG0535	radical SAM domain protein
IXO1104_08295	COG0535	radical SAM domain protein
IXO1104_08300	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
IXO1104_08315	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IXO1104_08325	COG1215	transferase activity, transferring glycosyl groups
IXO1104_08330	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IXO1104_08340	COG1199	ATP-dependent helicase activity
IXO1104_08350	COG1397	ADP-ribosylglycohydrolase
IXO1104_08360	COG0189	ligase activity
IXO1104_08375	COG0835	chemotaxis
IXO1104_08380	COG0840	transmembrane signaling receptor activity
IXO1104_08385	COG0643	Histidine kinase
IXO1104_08385	COG2198	Histidine kinase
IXO1104_08385	COG0784	Response regulator, receiver
IXO1104_08425	COG1446	asparaginase
IXO1104_08470	COG3537	Alpha-1,2-mannosidase
IXO1104_08530	COG1472	Belongs to the glycosyl hydrolase 3 family
IXO1104_08550	COG1388	LysM domain
IXO1104_08550	COG3858	chitin binding
IXO1104_08565	COG0837	glucose binding
IXO1104_08570	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IXO1104_08580	COG0494	nUDIX hydrolase
IXO1104_08590	COG3956	TIGRFAM MazG family protein
IXO1104_08605	COG0330	HflC and HflK could
IXO1104_08620	COG0509	glycine decarboxylation via glycine cleavage system
IXO1104_08655	COG1960	acyl-CoA dehydrogenase activity
IXO1104_08665	COG1309	transcriptional regulator
IXO1104_08670	COG4771	TonB-dependent receptor
IXO1104_08680	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IXO1104_08690	COG0463	Glycosyl transferase, family 2
IXO1104_08710	COG1272	protein, Hemolysin III
IXO1104_08715	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IXO1104_08720	COG0739	heme binding
IXO1104_08725	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IXO1104_08730	COG0626	cystathionine gamma-synthase activity
IXO1104_08740	COG1760	l-serine dehydratase
IXO1104_08755	COG2353	YceI-like domain
IXO1104_08765	COG2353	YceI-like domain
IXO1104_08835	COG1960	acyl-CoA dehydrogenase activity
IXO1104_08840	COG1024	Enoyl-CoA hydratase
IXO1104_08860	COG1250	3-hydroxyacyl-CoA dehydrogenase
IXO1104_08860	COG1024	Enoyl-CoA hydratase
IXO1104_08875	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IXO1104_08905	COG1381	Involved in DNA repair and RecF pathway recombination
IXO1104_08920	COG2954	triphosphatase activity
IXO1104_08935	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IXO1104_08940	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
IXO1104_08945	COG3046	protein related to deoxyribodipyrimidine photolyase
IXO1104_08955	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
IXO1104_08960	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IXO1104_08965	COG1278	Cold shock
IXO1104_08985	COG1201	RNA secondary structure unwinding
IXO1104_08990	COG1793	dna ligase
IXO1104_09000	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
IXO1104_09000	COG1793	dna ligase
IXO1104_09030	COG0183	Belongs to the thiolase family
IXO1104_09050	COG1451	nucleotide metabolic process
IXO1104_09070	COG3039	Transposase
IXO1104_09075	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IXO1104_09130	COG1047	Peptidyl-prolyl cis-trans
IXO1104_09145	COG2824	Alkylphosphonate utilization operon protein PhnA
IXO1104_09155	COG1902	pentaerythritol trinitrate reductase activity
IXO1104_09160	COG2814	Major facilitator Superfamily
IXO1104_09200	COG0392	lysyltransferase activity
IXO1104_09200	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IXO1104_09210	COG0251	oxidation-reduction process
IXO1104_09215	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IXO1104_09230	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IXO1104_09255	COG1595	DNA-templated transcription, initiation
IXO1104_09270	COG2878	Part of a membrane complex involved in electron transport
IXO1104_09280	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IXO1104_09280	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IXO1104_09300	COG0833	amino acid
IXO1104_09305	COG2040	homocysteine
IXO1104_09320	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IXO1104_09355	COG0529	Catalyzes the synthesis of activated sulfate
IXO1104_09355	COG2895	sulfate adenylyltransferase (ATP) activity
IXO1104_09400	COG1981	membrane
IXO1104_09430	COG4771	TonB-dependent receptor
IXO1104_09440	COG0825	malonyl-CoA metabolic process
IXO1104_09460	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IXO1104_09465	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IXO1104_09490	COG0750	zinc metalloprotease
IXO1104_09500	COG0575	Belongs to the CDS family
IXO1104_09510	COG0233	cytoplasmic translational termination
IXO1104_09525	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IXO1104_09585	COG1393	Belongs to the ArsC family
IXO1104_09600	COG0367	asparagine synthase
IXO1104_09610	COG4774	siderophore transport
IXO1104_09635	COG2207	Transcriptional regulator
IXO1104_09650	COG1566	PFAM secretion protein HlyD family protein
IXO1104_09655	COG2814	Major facilitator Superfamily
IXO1104_09700	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IXO1104_09710	COG1960	acyl-CoA dehydrogenase activity
IXO1104_09725	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IXO1104_09735	COG2914	Belongs to the UPF0125 (RnfH) family
IXO1104_09740	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IXO1104_09750	COG0497	DNA recombination
IXO1104_09760	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IXO1104_09765	COG0443	Heat shock 70 kDa protein
IXO1104_09770	COG0484	heat shock protein binding
IXO1104_09775	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
IXO1104_09795	COG0583	DNA-binding transcription factor activity
IXO1104_09810	COG1132	(ABC) transporter
IXO1104_09845	COG2850	peptidyl-arginine hydroxylation
IXO1104_09925	COG1131	(ABC) transporter
IXO1104_09930	COG1725	Transcriptional regulator
IXO1104_09940	COG0386	Belongs to the glutathione peroxidase family
IXO1104_09955	COG2900	Belongs to the SlyX family
IXO1104_09970	COG1609	Transcriptional regulator
IXO1104_09980	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IXO1104_09995	COG1410	methionine synthase
IXO1104_09995	COG0646	methionine synthase
IXO1104_10000	COG0646	methionine synthase
IXO1104_10000	COG1410	methionine synthase
IXO1104_10005	COG2226	methyltransferase
IXO1104_10010	COG1960	acyl-CoA dehydrogenase activity
IXO1104_10035	COG0557	exoribonuclease II activity
IXO1104_10050	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IXO1104_10060	COG3039	Transposase
IXO1104_10090	COG1278	Cold shock
IXO1104_10170	COG3039	Transposase
IXO1104_10180	COG0583	DNA-binding transcription factor activity
IXO1104_10245	COG0742	ribosomal rna small subunit methyltransferase
IXO1104_10250	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IXO1104_10265	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IXO1104_10270	COG0405	Gamma-glutamyltransferase
IXO1104_10380	COG3039	Transposase
IXO1104_10420	COG0343	queuine tRNA-ribosyltransferase activity
IXO1104_10425	COG1862	Preprotein translocase
IXO1104_10430	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IXO1104_10435	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IXO1104_10465	COG3328	transposase activity
IXO1104_10480	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IXO1104_10490	COG0704	Plays a role in the regulation of phosphate uptake
IXO1104_10505	COG0573	inorganic phosphate transmembrane transporter activity
IXO1104_10510	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IXO1104_10545	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IXO1104_10555	COG1024	Enoyl-CoA hydratase
IXO1104_10565	COG0494	nUDIX hydrolase
IXO1104_10610	COG0116	Belongs to the methyltransferase superfamily
IXO1104_10610	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IXO1104_10635	COG0667	Aldo Keto reductase
IXO1104_10645	COG2925	Exonuclease
IXO1104_10675	COG0288	reversible hydration of carbon dioxide
IXO1104_10705	COG0316	Belongs to the HesB IscA family
IXO1104_10710	COG0360	Binds together with S18 to 16S ribosomal RNA
IXO1104_10720	COG0359	binds to the 23S rRNA
IXO1104_10730	COG3115	cell septum assembly
IXO1104_10745	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
IXO1104_10760	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IXO1104_10785	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IXO1104_10795	COG2986	histidine ammonia-lyase
IXO1104_10800	COG1228	amidohydrolase
IXO1104_10840	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IXO1104_10850	COG0077	Prephenate dehydratase
IXO1104_10850	COG1605	Chorismate mutase
IXO1104_10855	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IXO1104_10885	COG4566	intracellular signal transduction
IXO1104_10930	COG0860	N-Acetylmuramoyl-L-alanine amidase
IXO1104_10935	COG1469	GTP cyclohydrolase I activity
IXO1104_10945	COG0617	tRNA 3'-terminal CCA addition
IXO1104_10955	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IXO1104_10960	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IXO1104_10990	COG1472	Belongs to the glycosyl hydrolase 3 family
IXO1104_11010	COG3706	GGDEF domain
IXO1104_11010	COG4251	negative regulation of phosphorylation
IXO1104_11010	COG5001	Diguanylate cyclase
IXO1104_11010	COG2203	Gaf domain
IXO1104_11095	COG0386	Belongs to the glutathione peroxidase family
IXO1104_11180	COG1247	-acetyltransferase
IXO1104_11200	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IXO1104_11205	COG3039	Transposase
IXO1104_11215	COG3039	Transposase
IXO1104_11240	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IXO1104_11255	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IXO1104_11260	COG1393	Belongs to the ArsC family
IXO1104_11265	COG0431	NADPH-dependent FMN reductase
IXO1104_11270	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IXO1104_11275	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IXO1104_11295	COG0784	Response regulator, receiver
IXO1104_11295	COG2205	protein histidine kinase activity
IXO1104_11295	COG5002	protein histidine kinase activity
IXO1104_11335	COG0800	Aldolase
IXO1104_11340	COG0129	dihydroxy-acid dehydratase activity
IXO1104_11345	COG0363	glucosamine-6-phosphate deaminase activity
IXO1104_11355	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IXO1104_11370	COG0354	folic acid binding
IXO1104_11385	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IXO1104_11400	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IXO1104_11415	COG4591	ABC-type transport system involved in lipoprotein release permease component
IXO1104_11440	COG0811	peptide transport
IXO1104_11455	COG1663	tetraacyldisaccharide 4'-kinase activity
IXO1104_11465	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IXO1104_11475	COG0322	excinuclease ABC activity
IXO1104_11525	COG2801	Transposase and inactivated derivatives
IXO1104_11535	COG2201	protein-glutamate methylesterase activity
IXO1104_11570	COG0653	protein targeting
IXO1104_11715	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IXO1104_11715	COG0140	phosphoribosyl-ATP diphosphatase activity
IXO1104_11725	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IXO1104_11735	COG0131	Imidazoleglycerol-phosphate dehydratase
IXO1104_11735	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IXO1104_11750	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IXO1104_11780	COG0124	histidyl-tRNA synthetase
IXO1104_11800	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IXO1104_11840	COG1012	belongs to the aldehyde dehydrogenase family
IXO1104_11865	COG0697	spore germination
IXO1104_11870	COG1794	racemase activity, acting on amino acids and derivatives
IXO1104_11895	COG0671	phosphoesterase, PA-phosphatase related
IXO1104_11910	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
IXO1104_11925	COG2183	response to ionizing radiation
IXO1104_11935	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IXO1104_11935	COG0723	plastoquinol--plastocyanin reductase activity
IXO1104_11950	COG3243	poly(R)-hydroxyalkanoic acid synthase
IXO1104_11960	COG1183	phosphatidylcholine synthase activity
IXO1104_11965	COG1028	Short-chain dehydrogenase reductase Sdr
IXO1104_11980	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
IXO1104_11990	COG0668	transmembrane transport
IXO1104_12010	COG1914	H( )-stimulated, divalent metal cation uptake system
IXO1104_12055	COG0583	DNA-binding transcription factor activity
IXO1104_12060	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IXO1104_12065	COG3002	Belongs to the UPF0753 family
IXO1104_12080	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IXO1104_12100	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IXO1104_12110	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IXO1104_12115	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
IXO1104_12125	COG0776	regulation of translation
IXO1104_12130	COG0539	negative regulation of cytoplasmic translation
IXO1104_12135	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IXO1104_12150	COG2957	Belongs to the agmatine deiminase family
IXO1104_12160	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IXO1104_12185	COG0395	ABC-type sugar transport system, permease component
IXO1104_12190	COG1175	transmembrane transport
IXO1104_12230	COG2350	Protein conserved in bacteria
IXO1104_12235	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IXO1104_12240	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IXO1104_12245	COG1187	pseudouridine synthase activity
IXO1104_12270	COG0436	Aminotransferase
IXO1104_12275	COG4133	protoheme IX ABC transporter activity
IXO1104_12335	COG0277	FAD linked oxidase domain protein
IXO1104_12340	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IXO1104_12350	COG0531	amino acid
IXO1104_12355	COG0531	amino acid
IXO1104_12365	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
IXO1104_12395	COG3039	Transposase
IXO1104_12410	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IXO1104_12480	COG0303	'Molybdopterin
IXO1104_12485	COG1160	GTP binding
IXO1104_12490	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IXO1104_12500	COG1426	Protein conserved in bacteria
IXO1104_12510	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IXO1104_12525	COG1024	Enoyl-CoA hydratase
IXO1104_12525	COG1250	3-hydroxyacyl-CoA dehydrogenase
IXO1104_12530	COG0183	Belongs to the thiolase family
IXO1104_12540	COG0038	chloride channel
IXO1104_12560	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IXO1104_12580	COG1674	ftsk spoiiie
IXO1104_12585	COG0492	ferredoxin-NADP+ reductase activity
IXO1104_12610	COG0542	response to heat
IXO1104_12625	COG0482	sulfurtransferase activity
IXO1104_12650	COG5001	Diguanylate cyclase
IXO1104_12655	COG4585	Histidine kinase
IXO1104_12665	COG5002	protein histidine kinase activity
IXO1104_12685	COG0784	Response regulator, receiver
IXO1104_12685	COG0835	chemotaxis
IXO1104_12695	COG1558	bacterial-type flagellum-dependent cell motility
IXO1104_12700	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
IXO1104_12710	COG4787	bacterial-type flagellum-dependent cell motility
IXO1104_12750	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IXO1104_12755	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IXO1104_12785	COG2201	protein-glutamate methylesterase activity
IXO1104_12805	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IXO1104_12815	COG1028	Short-chain dehydrogenase reductase Sdr
IXO1104_12850	COG1677	Flagellar hook-basal body complex protein FliE
IXO1104_12900	COG3190	flagellar
IXO1104_12915	COG1684	flagellar biosynthetic protein fliR
IXO1104_12970	COG0784	Response regulator, receiver
IXO1104_12970	COG0643	Histidine kinase
IXO1104_12970	COG2198	Histidine kinase
IXO1104_13000	COG3209	COG3209 Rhs family protein
IXO1104_13100	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IXO1104_13105	COG4988	ABC transporter
IXO1104_13115	COG1271	oxidase subunit
IXO1104_13145	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IXO1104_13165	COG0165	Argininosuccinate lyase
IXO1104_13180	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IXO1104_13185	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IXO1104_13195	COG0137	argininosuccinate synthase activity
IXO1104_13200	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IXO1104_13215	COG2166	iron-sulfur cluster assembly
IXO1104_13240	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IXO1104_13270	COG3039	Transposase
IXO1104_13290	COG4677	pectinesterase activity
IXO1104_13315	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IXO1104_13320	COG0402	S-adenosylhomocysteine deaminase activity
IXO1104_13335	COG1509	lysine 2,3-aminomutase activity
IXO1104_13340	COG3300	MHYT domain
IXO1104_13340	COG5001	Diguanylate cyclase
IXO1104_13355	COG0483	inositol monophosphate 1-phosphatase activity
IXO1104_13360	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IXO1104_13380	COG0488	(ABC) transporter
IXO1104_13385	COG0513	Belongs to the DEAD box helicase family
IXO1104_13390	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IXO1104_13405	COG0625	glutathione transferase activity
IXO1104_13410	COG1278	Cold shock
IXO1104_13415	COG1671	Belongs to the UPF0178 family
IXO1104_13420	COG4681	YaeQ
IXO1104_13425	COG2081	HI0933 family
IXO1104_13435	COG0501	Belongs to the peptidase M48B family
IXO1104_13445	COG1028	Short-chain dehydrogenase reductase Sdr
IXO1104_13465	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IXO1104_13470	COG0860	N-Acetylmuramoyl-L-alanine amidase
IXO1104_13475	COG0802	atpase or kinase
IXO1104_13480	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IXO1104_13480	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IXO1104_13485	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IXO1104_13505	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IXO1104_13580	COG3328	transposase activity
IXO1104_13615	COG2969	positive regulation of protein catabolic process
IXO1104_13620	COG0625	glutathione transferase activity
IXO1104_13625	COG2857	Cytochrome c1
IXO1104_13630	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IXO1104_13635	COG0723	plastoquinol--plastocyanin reductase activity
IXO1104_13640	COG0741	lytic transglycosylase activity
IXO1104_13660	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IXO1104_13665	COG1702	phosphate starvation-inducible protein PhoH
IXO1104_13685	COG4535	Mg2 and Co2 transporter CorC
IXO1104_13700	COG1012	belongs to the aldehyde dehydrogenase family
IXO1104_13710	COG1177	transmembrane transport
IXO1104_13720	COG3842	ATPase activity
IXO1104_13755	COG0174	glutamine synthetase
IXO1104_13760	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IXO1104_13770	COG0477	Major facilitator Superfamily
IXO1104_13780	COG0243	molybdopterin cofactor binding
IXO1104_13790	COG2223	nitrite transmembrane transporter activity
IXO1104_13800	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IXO1104_13805	COG1121	(ABC) transporter
IXO1104_13815	COG2733	membrane
IXO1104_13820	COG5002	protein histidine kinase activity
IXO1104_13820	COG0784	Response regulator, receiver
IXO1104_13820	COG2205	protein histidine kinase activity
IXO1104_13830	COG3039	Transposase
IXO1104_13835	COG2902	Dehydrogenase
IXO1104_13845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IXO1104_13850	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IXO1104_13870	COG1609	Transcriptional regulator
IXO1104_13875	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IXO1104_13875	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IXO1104_13880	COG1105	Belongs to the carbohydrate kinase PfkB family
IXO1104_13885	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IXO1104_13885	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IXO1104_13900	COG3039	Transposase
IXO1104_13920	COG3039	Transposase
IXO1104_14010	COG3039	Transposase
IXO1104_14065	COG4771	TonB-dependent receptor
IXO1104_14075	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IXO1104_14095	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IXO1104_14100	COG1360	Flagellar Motor Protein
IXO1104_14110	COG0835	chemotaxis
IXO1104_14120	COG0745	RESPONSE REGULATOR receiver
IXO1104_14150	COG0840	transmembrane signaling receptor activity
IXO1104_14160	COG0840	transmembrane signaling receptor activity
IXO1104_14170	COG0840	transmembrane signaling receptor activity
IXO1104_14180	COG0840	transmembrane signaling receptor activity
IXO1104_14185	COG0840	transmembrane signaling receptor activity
IXO1104_14190	COG0840	transmembrane signaling receptor activity
IXO1104_14195	COG0840	transmembrane signaling receptor activity
IXO1104_14210	COG0835	chemotaxis
IXO1104_14265	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IXO1104_14295	COG0318	PFAM AMP-dependent synthetase and ligase
IXO1104_14300	COG1024	Enoyl-CoA hydratase
IXO1104_14305	COG0784	Response regulator, receiver
IXO1104_14305	COG2198	Histidine kinase
IXO1104_14305	COG2205	protein histidine kinase activity
IXO1104_14375	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IXO1104_14385	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IXO1104_14390	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IXO1104_14400	COG0505	Belongs to the CarA family
IXO1104_14405	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IXO1104_14415	COG2258	MOSC domain
IXO1104_14420	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IXO1104_14470	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IXO1104_14490	COG0477	Major facilitator Superfamily
IXO1104_14500	COG1070	Carbohydrate kinase
IXO1104_14510	COG1501	Belongs to the glycosyl hydrolase 31 family
IXO1104_14525	COG0800	Aldolase
IXO1104_14530	COG4948	Mandelate Racemase Muconate Lactonizing
IXO1104_14540	COG3734	2-keto-3-deoxy-galactonokinase
IXO1104_14545	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IXO1104_14555	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IXO1104_14570	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IXO1104_14575	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
IXO1104_14585	COG0351	phosphomethylpyrimidine kinase
IXO1104_14615	COG0583	DNA-binding transcription factor activity
IXO1104_14620	COG1741	Belongs to the pirin family
IXO1104_14645	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IXO1104_14650	COG0305	Participates in initiation and elongation during chromosome replication
IXO1104_14670	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IXO1104_14675	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IXO1104_14680	COG2137	regulation of response to DNA damage stimulus
IXO1104_14685	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IXO1104_14700	COG1546	Belongs to the CinA family
IXO1104_14705	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IXO1104_14715	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IXO1104_14720	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IXO1104_14730	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
IXO1104_14735	COG1534	Rna-binding protein
IXO1104_14750	COG1238	metal cluster binding
IXO1104_14755	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IXO1104_14760	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
IXO1104_14765	COG2840	Smr protein MutS2
IXO1104_14775	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
IXO1104_14785	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
IXO1104_14790	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IXO1104_14795	COG0148	phosphopyruvate hydratase activity
IXO1104_14805	COG2877	3-deoxy-8-phosphooctulonate synthase activity
IXO1104_14810	COG0504	CTP synthase activity
IXO1104_14835	COG1434	Gram-negative-bacterium-type cell wall biogenesis
IXO1104_14840	COG0306	phosphate transporter
IXO1104_14850	COG1253	flavin adenine dinucleotide binding
IXO1104_14865	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IXO1104_14875	COG0477	Major facilitator Superfamily
IXO1104_14885	COG1132	(ABC) transporter
IXO1104_14890	COG1136	(ABC) transporter
IXO1104_14905	COG0438	transferase activity, transferring glycosyl groups
IXO1104_14915	COG2264	protein methyltransferase activity
IXO1104_14945	COG2244	polysaccharide biosynthetic process
IXO1104_14995	COG1595	DNA-templated transcription, initiation
IXO1104_15010	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IXO1104_15030	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IXO1104_15110	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IXO1104_15115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IXO1104_15165	COG1858	cytochrome C peroxidase
IXO1104_15195	COG0515	serine threonine protein kinase
IXO1104_15200	COG0631	protein serine/threonine phosphatase activity
IXO1104_15310	COG3039	Transposase
IXO1104_15340	COG3039	Transposase
IXO1104_15345	COG3039	Transposase
IXO1104_15370	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
IXO1104_15370	COG0316	Belongs to the HesB IscA family
IXO1104_15375	COG2154	pterin-4-alpha-carbinolamine dehydratase
IXO1104_15385	COG0428	transporter
IXO1104_15390	COG0428	transporter
IXO1104_15395	COG3064	Membrane
IXO1104_15405	COG1530	ribonuclease E activity
IXO1104_15420	COG1054	Belongs to the UPF0176 family
IXO1104_15440	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IXO1104_15475	COG3039	Transposase
IXO1104_15510	COG1648	precorrin-2 dehydrogenase activity
IXO1104_15510	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IXO1104_15535	COG0746	molybdenum cofactor guanylyltransferase activity
IXO1104_15560	COG3039	Transposase
IXO1104_15610	COG4206	TonB-dependent receptor
IXO1104_15640	COG0531	amino acid
IXO1104_15655	COG0006	proline dipeptidase activity
IXO1104_15665	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IXO1104_15680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IXO1104_15685	COG3938	Belongs to the proline racemase family
IXO1104_15695	COG0552	protein localization to endoplasmic reticulum
IXO1104_15715	COG0784	Response regulator, receiver
IXO1104_15715	COG4191	Histidine kinase
IXO1104_15805	COG3040	lipid binding
IXO1104_15850	COG0438	transferase activity, transferring glycosyl groups
IXO1104_15860	COG0438	transferase activity, transferring glycosyl groups
IXO1104_15865	COG0438	transferase activity, transferring glycosyl groups
IXO1104_15920	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IXO1104_15925	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IXO1104_15935	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IXO1104_15975	COG0556	nucleotide-excision repair
IXO1104_15980	COG4969	Belongs to the N-Me-Phe pilin family
IXO1104_16045	COG4695	Portal protein
IXO1104_16090	COG3179	chitinase
IXO1104_16285	COG1611	Belongs to the LOG family
IXO1104_16300	COG2095	MarC family integral membrane protein
IXO1104_16310	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IXO1104_16345	COG1185	polyribonucleotide nucleotidyltransferase activity
IXO1104_16350	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IXO1104_16370	COG0195	Participates in both transcription termination and antitermination
IXO1104_16375	COG0779	Required for maturation of 30S ribosomal subunits
IXO1104_16385	COG1007	ATP synthesis coupled electron transport
IXO1104_16415	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
IXO1104_16420	COG1034	ATP synthesis coupled electron transport
IXO1104_16425	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IXO1104_16430	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
IXO1104_16435	COG0649	NAD binding
IXO1104_16440	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IXO1104_16450	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IXO1104_16465	COG0149	triose-phosphate isomerase activity
IXO1104_16515	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IXO1104_16520	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IXO1104_16525	COG0159	tryptophan synthase activity
IXO1104_16535	COG0133	tryptophan synthase activity
IXO1104_16545	COG0135	phosphoribosylanthranilate isomerase activity
IXO1104_16550	COG0101	tRNA pseudouridine synthase activity
IXO1104_16570	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IXO1104_16575	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IXO1104_16580	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IXO1104_16585	COG2890	protein-(glutamine-N5) methyltransferase activity
IXO1104_16635	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IXO1104_16640	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IXO1104_16660	COG3039	Transposase
IXO1104_16815	COG3179	chitinase
IXO1104_16860	COG4695	Portal protein
IXO1104_16905	COG3039	Transposase
IXO1104_16915	COG0412	Dienelactone hydrolase
IXO1104_16935	COG0717	Belongs to the dCTP deaminase family
IXO1104_16940	COG0489	protein tyrosine kinase activity
IXO1104_16980	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IXO1104_16985	COG2311	Membrane
IXO1104_16990	COG1047	Peptidyl-prolyl cis-trans
IXO1104_16995	COG0791	NLP P60 protein
IXO1104_17000	COG0791	NLP P60 protein
IXO1104_17015	COG1301	dicarboxylic acid transport
IXO1104_17020	COG1785	Belongs to the alkaline phosphatase family
IXO1104_17025	COG0037	tRNA processing
IXO1104_17030	COG1722	exodeoxyribonuclease VII activity
IXO1104_17035	COG0142	geranyltranstransferase activity
IXO1104_17060	COG0312	modulator of DNA gyrase
IXO1104_17065	COG3028	Belongs to the UPF0307 family
IXO1104_17070	COG0312	modulator of DNA gyrase
IXO1104_17080	COG3164	Protein of unknown function
IXO1104_17095	COG2968	Membrane
IXO1104_17100	COG3039	Transposase
IXO1104_17130	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IXO1104_17155	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IXO1104_17180	COG3118	belongs to the thioredoxin family
IXO1104_17240	COG3039	Transposase
IXO1104_17270	COG3039	Transposase
IXO1104_17310	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IXO1104_17315	COG1845	cytochrome c oxidase, subunit III
IXO1104_17320	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IXO1104_17335	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IXO1104_17340	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IXO1104_17350	COG0196	riboflavin kinase activity
IXO1104_17355	COG0728	peptidoglycan biosynthetic process
IXO1104_17360	COG0268	Binds directly to 16S ribosomal RNA
IXO1104_17365	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IXO1104_17370	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IXO1104_17380	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IXO1104_17385	COG0824	Thioesterase
IXO1104_17400	COG1946	Acyl-CoA thioesterase
IXO1104_17410	COG1595	DNA-templated transcription, initiation
IXO1104_17425	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
IXO1104_17465	COG1877	trehalose-phosphatase activity
IXO1104_17470	COG3387	PFAM Glycoside hydrolase 15-related
IXO1104_17495	COG0564	pseudouridine synthase activity
IXO1104_17500	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IXO1104_17505	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IXO1104_17505	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IXO1104_17515	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IXO1104_17520	COG0045	succinate-CoA ligase (ADP-forming) activity
IXO1104_17560	COG2194	sulfuric ester hydrolase activity
IXO1104_17565	COG4969	Belongs to the N-Me-Phe pilin family
IXO1104_17575	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
IXO1104_17615	COG3209	COG3209 Rhs family protein
IXO1104_17630	COG3039	Transposase
IXO1104_17645	COG3039	Transposase
IXO1104_17680	COG1132	(ABC) transporter
IXO1104_17710	COG0745	RESPONSE REGULATOR receiver
IXO1104_17715	COG5002	protein histidine kinase activity
IXO1104_17715	COG5000	phosphorelay sensor kinase activity
IXO1104_17720	COG0475	glutathione-regulated potassium exporter activity
IXO1104_17730	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IXO1104_17750	COG1187	pseudouridine synthase activity
IXO1104_17755	COG5001	Diguanylate cyclase
IXO1104_17755	COG5002	protein histidine kinase activity
IXO1104_17875	COG1028	Short-chain dehydrogenase reductase Sdr
IXO1104_17890	COG0415	Belongs to the DNA photolyase family
IXO1104_17895	COG0305	Participates in initiation and elongation during chromosome replication
IXO1104_17905	COG0367	asparagine synthase
IXO1104_17945	COG0084	hydrolase, TatD family'
IXO1104_17950	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IXO1104_18010	COG0735	belongs to the Fur family
IXO1104_18015	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IXO1104_18040	COG3039	Transposase
IXO1104_18090	COG2205	protein histidine kinase activity
IXO1104_18105	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IXO1104_18115	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IXO1104_18130	COG0643	Histidine kinase
IXO1104_18130	COG2198	Histidine kinase
IXO1104_18135	COG0840	transmembrane signaling receptor activity
IXO1104_18140	COG0835	chemotaxis
IXO1104_18145	COG2202	Pas domain
IXO1104_18145	COG2200	EAL domain
IXO1104_18145	COG2199	diguanylate cyclase activity
IXO1104_18150	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IXO1104_18165	COG3590	peptidase
IXO1104_18180	COG0588	phosphoglycerate mutase activity
IXO1104_18185	COG1515	deoxyribonuclease V activity
IXO1104_18195	COG1741	Belongs to the pirin family
IXO1104_18255	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IXO1104_18385	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IXO1104_18400	COG2197	response regulator
IXO1104_18405	COG4585	Histidine kinase
IXO1104_18425	COG2894	cell division
IXO1104_18430	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
IXO1104_18440	COG0642	Histidine kinase
IXO1104_18445	COG0745	RESPONSE REGULATOR receiver
IXO1104_18450	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IXO1104_18460	COG2194	sulfuric ester hydrolase activity
IXO1104_18490	COG3551	Protein conserved in bacteria
IXO1104_18550	COG0203	ribosomal protein L17
IXO1104_18560	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IXO1104_18565	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IXO1104_18575	COG0201	protein transport
IXO1104_18585	COG1841	ribosomal large subunit assembly
IXO1104_18615	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IXO1104_18625	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IXO1104_18630	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IXO1104_18635	COG0255	Belongs to the universal ribosomal protein uL29 family
IXO1104_18640	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IXO1104_18650	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IXO1104_18665	COG0089	rRNA binding
IXO1104_18670	COG0088	Forms part of the polypeptide exit tunnel
IXO1104_18675	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IXO1104_18680	COG0051	transcription antitermination factor activity, RNA binding
IXO1104_18700	COG0049	tRNA binding
IXO1104_18705	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IXO1104_18710	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IXO1104_18715	COG0085	RNA polymerase activity
IXO1104_18720	COG0222	ribosome binding
IXO1104_18725	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IXO1104_18735	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IXO1104_18740	COG0250	Participates in transcription elongation, termination and antitermination
IXO1104_18745	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IXO1104_18775	COG0012	GTP binding
IXO1104_18780	COG0193	aminoacyl-tRNA hydrolase activity
IXO1104_18790	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IXO1104_18805	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
IXO1104_18815	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IXO1104_18820	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IXO1104_18830	COG0521	Mo-molybdopterin cofactor biosynthetic process
IXO1104_18850	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IXO1104_18855	COG1295	ribonuclease BN
IXO1104_18885	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IXO1104_18890	COG1404	Belongs to the peptidase S8 family
IXO1104_18905	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IXO1104_18930	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
IXO1104_18955	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
IXO1104_18970	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IXO1104_18970	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IXO1104_19010	COG2890	protein-(glutamine-N5) methyltransferase activity
IXO1104_19020	COG3634	alkyl hydroperoxide reductase activity
IXO1104_19025	COG0583	DNA-binding transcription factor activity
IXO1104_19030	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IXO1104_19035	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IXO1104_19080	COG2197	response regulator
IXO1104_19185	COG3386	PFAM SMP-30 Gluconolaconase
IXO1104_19205	COG1024	Enoyl-CoA hydratase
IXO1104_19215	COG0318	PFAM AMP-dependent synthetase and ligase
IXO1104_19220	COG0583	DNA-binding transcription factor activity
IXO1104_19260	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IXO1104_19265	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IXO1104_19275	COG2096	Adenosyltransferase
IXO1104_19280	COG0123	including yeast histone deacetylase and acetoin utilization protein
IXO1104_19295	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IXO1104_19305	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IXO1104_19310	COG2967	ApaG domain
IXO1104_19315	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IXO1104_19340	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IXO1104_19360	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IXO1104_19380	COG0642	Histidine kinase
IXO1104_19395	COG4181	ATPase activity
IXO1104_19405	COG2175	clavaminate synthase activity
IXO1104_19455	COG0667	Aldo Keto reductase
IXO1104_19465	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IXO1104_19470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IXO1104_19480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IXO1104_19495	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IXO1104_19530	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IXO1104_19535	COG2226	methyltransferase
IXO1104_19585	COG3321	synthase
IXO1104_19585	COG1028	Short-chain dehydrogenase reductase Sdr
IXO1104_19585	COG0604	alcohol dehydrogenase
IXO1104_19595	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IXO1104_19610	COG0494	nUDIX hydrolase
IXO1104_19620	COG0653	protein targeting
IXO1104_19625	COG4942	peptidase
IXO1104_19625	COG1388	LysM domain
IXO1104_19635	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
IXO1104_19650	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IXO1104_19655	COG1181	Belongs to the D-alanine--D-alanine ligase family
IXO1104_19660	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IXO1104_19675	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IXO1104_19680	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IXO1104_19695	COG3116	cell division
IXO1104_19700	COG0275	rRNA processing
IXO1104_19735	COG0792	nuclease activity
IXO1104_19740	COG1988	membrane-bound metal-dependent
IXO1104_19745	COG0277	FAD linked oxidase domain protein
IXO1104_19750	COG0745	RESPONSE REGULATOR receiver
IXO1104_19755	COG2205	protein histidine kinase activity
IXO1104_19765	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
IXO1104_19770	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IXO1104_19790	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IXO1104_19795	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IXO1104_19800	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
IXO1104_19820	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IXO1104_19820	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IXO1104_19840	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IXO1104_19860	COG0488	(ABC) transporter
IXO1104_19910	COG2205	protein histidine kinase activity
IXO1104_19945	COG2205	protein histidine kinase activity
IXO1104_19960	COG0218	Necessary for normal cell division and for the maintenance of normal septation
IXO1104_20085	COG1649	PFAM Uncharacterised BCR, COG1649
IXO1104_20085	COG0726	polysaccharide deacetylase
IXO1104_20090	COG1215	transferase activity, transferring glycosyl groups
IXO1104_20100	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IXO1104_20105	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IXO1104_20110	COG1609	Transcriptional regulator
IXO1104_20120	COG2188	Transcriptional regulator
IXO1104_20135	COG3250	beta-galactosidase activity
IXO1104_20185	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IXO1104_20190	COG4191	Histidine kinase
IXO1104_20195	COG0784	Response regulator, receiver
IXO1104_20200	COG4251	negative regulation of phosphorylation
IXO1104_20205	COG2823	Periplasmic or secreted lipoprotein
IXO1104_20210	COG0673	inositol 2-dehydrogenase activity
IXO1104_20215	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
IXO1104_20250	COG1056	cytidyltransferase-related domain
IXO1104_20250	COG1051	belongs to the nudix hydrolase family
IXO1104_20275	COG2921	Belongs to the UPF0250 family
IXO1104_20285	COG1686	Belongs to the peptidase S11 family
IXO1104_20290	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IXO1104_20295	COG2951	lytic endotransglycosylase activity
IXO1104_20315	COG0772	Belongs to the SEDS family
IXO1104_20330	COG1792	Involved in formation and maintenance of cell shape
IXO1104_20335	COG1077	Cell shape determining protein MreB Mrl
IXO1104_20340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IXO1104_20385	COG2199	diguanylate cyclase activity
IXO1104_20390	COG0308	aminopeptidase N
IXO1104_20420	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IXO1104_20450	COG0436	Aminotransferase
IXO1104_20465	COG1505	serine-type exopeptidase activity
IXO1104_20490	COG0181	hydroxymethylbilane synthase activity
IXO1104_20500	COG3275	phosphorelay sensor kinase activity
IXO1104_20550	COG0659	secondary active sulfate transmembrane transporter activity
IXO1104_20555	COG5297	Belongs to the glycosyl hydrolase family 6
IXO1104_20555	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IXO1104_20565	COG0840	transmembrane signaling receptor activity
IXO1104_20620	COG3039	Transposase
IXO1104_20640	COG0598	Magnesium transport protein CorA
IXO1104_20650	COG1113	amino acid transport
IXO1104_20655	COG5297	Belongs to the glycosyl hydrolase family 6
IXO1104_20660	COG4305	rare lipoprotein A
IXO1104_20665	COG0697	spore germination
IXO1104_20720	COG4221	oxidoreductase activity
IXO1104_20750	COG0456	acetyltransferase
IXO1104_20760	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IXO1104_20805	COG2111	Na H antiporter
IXO1104_20805	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IXO1104_20810	COG1006	Multisubunit Na H antiporter MnhC subunit
IXO1104_20815	COG0651	ATP synthesis coupled electron transport
IXO1104_20825	COG2212	antiporter activity
IXO1104_20830	COG1320	monovalent cation:proton antiporter activity
IXO1104_20840	COG3039	Transposase
IXO1104_20845	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
IXO1104_20865	COG3104	oligopeptide transport
IXO1104_20870	COG3483	tryptophan 2,3-dioxygenase activity
IXO1104_20880	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IXO1104_20915	COG0183	Belongs to the thiolase family
IXO1104_20985	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
IXO1104_20990	COG3023	N-Acetylmuramoyl-L-alanine amidase
IXO1104_21000	COG4948	Mandelate Racemase Muconate Lactonizing
IXO1104_21025	COG0531	amino acid
IXO1104_21050	COG4682	membrane
IXO1104_21055	COG2133	pyrroloquinoline quinone binding
IXO1104_21110	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IXO1104_21115	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IXO1104_21125	COG1610	YqeY-like protein
IXO1104_21140	COG1295	ribonuclease BN
IXO1104_21145	COG0358	DNA primase activity
IXO1104_21190	COG3039	Transposase
IXO1104_21330	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IXO1104_21340	COG1560	Kdo2-lipid A biosynthetic process
IXO1104_21390	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IXO1104_21390	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IXO1104_21395	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IXO1104_21400	COG0242	peptide deformylase activity
IXO1104_21405	COG1652	LysM domain
IXO1104_21410	COG0758	DNA mediated transformation
IXO1104_21415	COG2922	Belongs to the Smg family
IXO1104_21430	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IXO1104_21430	COG1754	DNA topoisomerase type I activity
IXO1104_21435	COG0009	L-threonylcarbamoyladenylate synthase
IXO1104_21450	COG1028	Short-chain dehydrogenase reductase Sdr
IXO1104_21460	COG0616	signal peptide processing
IXO1104_21465	COG0534	Mate efflux family protein
IXO1104_21485	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IXO1104_21520	COG1324	tolerance protein
IXO1104_21530	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
IXO1104_21535	COG0511	ligase activity, forming carbon-carbon bonds
IXO1104_21545	COG0439	Biotin carboxylase
IXO1104_21590	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
IXO1104_21660	COG3210	domain, Protein
IXO1104_21700	COG3210	domain, Protein
IXO1104_21705	COG2831	hemolysin activation secretion protein
IXO1104_21735	COG2267	carboxylic ester hydrolase activity
IXO1104_21740	COG2267	carboxylic ester hydrolase activity
IXO1104_21745	COG2267	carboxylic ester hydrolase activity
IXO1104_21760	COG0419	ATPase involved in DNA repair
IXO1104_21770	COG0151	Belongs to the GarS family
IXO1104_21790	COG1289	transmembrane transporter activity
IXO1104_21805	COG2814	Major facilitator Superfamily
IXO1104_21820	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
IXO1104_21855	COG0745	RESPONSE REGULATOR receiver
IXO1104_21900	COG0739	heme binding
IXO1104_21915	COG2211	Major facilitator Superfamily
IXO1104_21920	COG0708	Exodeoxyribonuclease III
IXO1104_21935	COG1192	Involved in chromosome partitioning
IXO1104_21940	COG1475	DNA binding
IXO1104_21955	COG0463	Glycosyl transferase, family 2
IXO1104_21980	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IXO1104_22005	COG4221	oxidoreductase activity
IXO1104_22030	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IXO1104_22035	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IXO1104_22050	COG3485	protocatechuate 3,4-dioxygenase
IXO1104_22055	COG3485	protocatechuate 3,4-dioxygenase
IXO1104_22095	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IXO1104_22100	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IXO1104_22110	COG0045	succinate-CoA ligase (ADP-forming) activity
IXO1104_22110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IXO1104_22110	COG1042	CoA-binding domain protein
IXO1104_22120	COG2239	Acts as a magnesium transporter
IXO1104_22135	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IXO1104_22155	COG3100	YcgL domain-containing protein
IXO1104_22160	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IXO1104_22170	COG0463	Glycosyl transferase, family 2
IXO1104_22185	COG1028	Short-chain dehydrogenase reductase Sdr
IXO1104_22195	COG0156	8-amino-7-oxononanoate synthase activity
IXO1104_22200	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IXO1104_22205	COG1040	competence protein
IXO1104_22210	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IXO1104_22220	COG0582	viral genome integration into host DNA
IXO1104_22275	COG0464	growth
IXO1104_22290	COG0628	permease
IXO1104_22300	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IXO1104_22310	COG1595	DNA-templated transcription, initiation
IXO1104_22315	COG0753	catalase activity
IXO1104_22365	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IXO1104_22370	COG0180	Tryptophanyl-tRNA synthetase
IXO1104_22375	COG3237	CsbD-like
IXO1104_22410	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IXO1104_22425	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IXO1104_22430	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
IXO1104_22430	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
IXO1104_22470	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IXO1104_22490	COG1566	PFAM secretion protein HlyD family protein
IXO1104_22505	COG1199	ATP-dependent helicase activity
IXO1104_22545	COG0583	DNA-binding transcription factor activity
IXO1104_22590	COG0625	glutathione transferase activity
IXO1104_22625	COG4555	ABC transporter
IXO1104_22635	COG1476	TRANSCRIPTIONal
IXO1104_22665	COG1131	(ABC) transporter
IXO1104_22670	COG0842	Transport permease protein
IXO1104_22760	COG1181	Belongs to the D-alanine--D-alanine ligase family
IXO1104_22770	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IXO1104_22780	COG0564	pseudouridine synthase activity
IXO1104_22810	COG0339	signal peptide processing
IXO1104_22840	COG3254	rhamnose metabolic process
IXO1104_22845	COG0738	Major facilitator superfamily
IXO1104_22850	COG1414	Transcriptional regulator
IXO1104_22865	COG2205	protein histidine kinase activity
IXO1104_22875	COG3459	Glycosyltransferase 36 associated
IXO1104_22880	COG2211	Major facilitator Superfamily
IXO1104_22885	COG3265	gluconokinase activity
IXO1104_22890	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IXO1104_22930	COG3039	Transposase
IXO1104_22990	COG1127	ABC transporter
IXO1104_22995	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IXO1104_23000	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IXO1104_23015	COG2853	Lipoprotein
IXO1104_23040	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IXO1104_23105	COG0676	glucose-6-phosphate 1-epimerase activity
IXO1104_23130	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IXO1104_23140	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IXO1104_23150	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IXO1104_23155	COG1064	alcohol dehydrogenase
IXO1104_23205	COG1522	sequence-specific DNA binding
IXO1104_23210	COG3186	Phenylalanine-4-hydroxylase
IXO1104_23250	COG0656	L-ascorbic acid biosynthetic process
IXO1104_23255	COG2130	NADP-dependent
IXO1104_23260	COG0667	Aldo Keto reductase
IXO1104_23270	COG1187	pseudouridine synthase activity
IXO1104_23285	COG1643	Atp-dependent helicase
IXO1104_23290	COG4807	Protein conserved in bacteria
IXO1104_23295	COG4948	Mandelate Racemase Muconate Lactonizing
IXO1104_23300	COG0179	Fumarylacetoacetate (FAA) hydrolase
IXO1104_23305	COG1028	Short-chain dehydrogenase reductase Sdr
IXO1104_23325	COG3507	Belongs to the glycosyl hydrolase 43 family
IXO1104_23365	COG3162	membrane
IXO1104_23370	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IXO1104_23385	COG0708	Exodeoxyribonuclease III
IXO1104_23400	COG2091	lysine biosynthetic process via aminoadipic acid
IXO1104_23410	COG3540	Alkaline phosphatase
IXO1104_23415	COG0357	Ribosomal RNA small subunit methyltransferase G
IXO1104_23440	COG2159	amidohydrolase
IXO1104_23455	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IXO1104_23460	COG0583	DNA-binding transcription factor activity
IXO1104_23465	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IXO1104_23480	COG0210	DNA helicase
IXO1104_23500	COG0531	amino acid
IXO1104_23510	COG1322	Protein conserved in bacteria
IXO1104_23520	COG0386	Belongs to the glutathione peroxidase family
IXO1104_23570	COG0793	Belongs to the peptidase S41A family
IXO1104_23575	COG4942	peptidase
IXO1104_23585	COG2234	aminopeptidase activity
IXO1104_23630	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IXO1104_23635	COG0302	gtp cyclohydrolase
IXO1104_23665	COG0477	Major facilitator Superfamily
IXO1104_23675	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IXO1104_23750	COG1192	Involved in chromosome partitioning
IXO1104_23780	COG1929	Belongs to the glycerate kinase type-1 family
IXO1104_23785	COG2271	Major facilitator Superfamily
IXO1104_23800	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IXO1104_23805	COG0861	Integral membrane protein TerC family
IXO1104_23815	COG0584	glycerophosphoryl diester phosphodiesterase
IXO1104_23825	COG0671	phosphoesterase, PA-phosphatase related
IXO1104_23835	COG0726	polysaccharide deacetylase
IXO1104_23840	COG0706	membrane insertase activity