locus-tag	class	description
IXO597_000005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IXO597_000020	COG0187	DNA topoisomerase II activity
IXO597_000030	COG0501	Belongs to the peptidase M48B family
IXO597_000060	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IXO597_000070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IXO597_000080	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
IXO597_000090	COG4772	TonB-dependent receptor
IXO597_000105	COG3039	Transposase
IXO597_000110	COG1304	FMN binding
IXO597_000130	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IXO597_000140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IXO597_000230	COG2826	transposase and inactivated derivatives, IS30 family
IXO597_000255	COG3039	Transposase
IXO597_000265	COG1090	epimerase
IXO597_000275	COG0642	Histidine kinase
IXO597_000285	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IXO597_000390	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IXO597_000450	COG3328	transposase activity
IXO597_000470	COG3264	Mechanosensitive ion channel
IXO597_000470	COG1511	domain protein
IXO597_000485	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IXO597_000490	COG2354	Protein conserved in bacteria
IXO597_000495	COG1649	PFAM Uncharacterised BCR, COG1649
IXO597_000515	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IXO597_000540	COG0702	epimerase
IXO597_000555	COG1858	cytochrome C peroxidase
IXO597_000620	COG0513	Belongs to the DEAD box helicase family
IXO597_000625	COG3039	Transposase
IXO597_000670	COG1116	anion transmembrane transporter activity
IXO597_000695	COG3039	Transposase
IXO597_000710	COG1136	(ABC) transporter
IXO597_000755	COG1272	protein, Hemolysin III
IXO597_000760	COG1111	helicase
IXO597_000760	COG1205	dead DEAH box helicase
IXO597_000830	COG0067	glutamate synthase
IXO597_000830	COG0070	glutamate synthase
IXO597_000830	COG0069	glutamate synthase activity
IXO597_000835	COG0493	'glutamate synthase
IXO597_000890	COG1609	Transcriptional regulator
IXO597_000920	COG0366	Alpha amylase catalytic
IXO597_000925	COG0366	Alpha amylase catalytic
IXO597_001025	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IXO597_001030	COG3265	gluconokinase activity
IXO597_001035	COG2211	Major facilitator Superfamily
IXO597_001040	COG3459	Glycosyltransferase 36 associated
IXO597_001050	COG2205	protein histidine kinase activity
IXO597_001065	COG1414	Transcriptional regulator
IXO597_001070	COG0738	Major facilitator superfamily
IXO597_001075	COG3254	rhamnose metabolic process
IXO597_001105	COG0339	signal peptide processing
IXO597_001130	COG0564	pseudouridine synthase activity
IXO597_001140	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IXO597_001150	COG1181	Belongs to the D-alanine--D-alanine ligase family
IXO597_001225	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IXO597_001235	COG0842	Transport permease protein
IXO597_001240	COG1131	(ABC) transporter
IXO597_001245	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IXO597_001270	COG1476	TRANSCRIPTIONal
IXO597_001280	COG4555	ABC transporter
IXO597_001315	COG0625	glutathione transferase activity
IXO597_001375	COG0583	DNA-binding transcription factor activity
IXO597_001410	COG3039	Transposase
IXO597_001465	COG3039	Transposase
IXO597_001475	COG3039	Transposase
IXO597_001490	COG1199	ATP-dependent helicase activity
IXO597_001585	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IXO597_001625	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
IXO597_001625	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
IXO597_001630	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IXO597_001645	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IXO597_001680	COG3237	CsbD-like
IXO597_001685	COG0180	Tryptophanyl-tRNA synthetase
IXO597_001690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IXO597_001735	COG0753	catalase activity
IXO597_001740	COG1595	DNA-templated transcription, initiation
IXO597_001750	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IXO597_001760	COG0628	permease
IXO597_001770	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IXO597_001775	COG1040	competence protein
IXO597_001780	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IXO597_001785	COG0156	8-amino-7-oxononanoate synthase activity
IXO597_001795	COG1028	Short-chain dehydrogenase reductase Sdr
IXO597_001815	COG0463	Glycosyl transferase, family 2
IXO597_001825	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IXO597_001830	COG3100	YcgL domain-containing protein
IXO597_001850	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IXO597_001865	COG2239	Acts as a magnesium transporter
IXO597_001880	COG0045	succinate-CoA ligase (ADP-forming) activity
IXO597_001880	COG1042	CoA-binding domain protein
IXO597_001880	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IXO597_001890	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IXO597_001895	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IXO597_001930	COG3485	protocatechuate 3,4-dioxygenase
IXO597_001935	COG3485	protocatechuate 3,4-dioxygenase
IXO597_001945	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IXO597_001950	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IXO597_001955	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IXO597_001980	COG4221	oxidoreductase activity
IXO597_002005	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IXO597_002030	COG0463	Glycosyl transferase, family 2
IXO597_002045	COG1475	DNA binding
IXO597_002050	COG1192	Involved in chromosome partitioning
IXO597_002065	COG0708	Exodeoxyribonuclease III
IXO597_002070	COG2211	Major facilitator Superfamily
IXO597_002090	COG0739	heme binding
IXO597_002135	COG0745	RESPONSE REGULATOR receiver
IXO597_002175	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
IXO597_002190	COG2814	Major facilitator Superfamily
IXO597_002215	COG1289	transmembrane transporter activity
IXO597_002225	COG0577	efflux transmembrane transporter activity
IXO597_002225	COG1136	(ABC) transporter
IXO597_002230	COG0151	Belongs to the GarS family
IXO597_002250	COG2267	carboxylic ester hydrolase activity
IXO597_002255	COG2267	carboxylic ester hydrolase activity
IXO597_002260	COG2267	carboxylic ester hydrolase activity
IXO597_002290	COG3039	Transposase
IXO597_002305	COG3328	transposase activity
IXO597_002325	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
IXO597_002370	COG0439	Biotin carboxylase
IXO597_002380	COG0511	ligase activity, forming carbon-carbon bonds
IXO597_002385	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
IXO597_002400	COG1324	tolerance protein
IXO597_002405	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IXO597_002425	COG0534	Mate efflux family protein
IXO597_002430	COG0616	signal peptide processing
IXO597_002440	COG1028	Short-chain dehydrogenase reductase Sdr
IXO597_002460	COG0009	L-threonylcarbamoyladenylate synthase
IXO597_002465	COG1754	DNA topoisomerase type I activity
IXO597_002465	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IXO597_002480	COG2922	Belongs to the Smg family
IXO597_002485	COG0758	DNA mediated transformation
IXO597_002490	COG1652	LysM domain
IXO597_002495	COG0242	peptide deformylase activity
IXO597_002500	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IXO597_002505	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IXO597_002505	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IXO597_002555	COG1560	Kdo2-lipid A biosynthetic process
IXO597_002565	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IXO597_002730	COG1294	oxidase, subunit
IXO597_002735	COG1271	oxidase subunit
IXO597_002745	COG2204	response regulator
IXO597_002770	COG2972	Histidine kinase
IXO597_002785	COG0531	amino acid
IXO597_002805	COG3590	peptidase
IXO597_002820	COG0667	Aldo Keto reductase
IXO597_002835	COG3384	dioxygenase
IXO597_002845	COG1573	uracil-dna glycosylase
IXO597_002855	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
IXO597_002865	COG0025	NhaP-type Na H and K H
IXO597_002870	COG1131	(ABC) transporter
IXO597_002875	COG0842	Transport permease protein
IXO597_002890	COG1404	Belongs to the peptidase S8 family
IXO597_002905	COG0745	RESPONSE REGULATOR receiver
IXO597_002955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IXO597_002980	COG2202	Pas domain
IXO597_002980	COG2205	protein histidine kinase activity
IXO597_003020	COG2813	Specifically methylates the guanine in position
IXO597_003025	COG1187	pseudouridine synthase activity
IXO597_003030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IXO597_003065	COG0697	spore germination
IXO597_003075	COG2011	ABC-type metal ion transport system permease component
IXO597_003105	COG0508	dehydrogenase complex catalyzes the overall conversion of
IXO597_003115	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IXO597_003135	COG0356	it plays a direct role in the translocation of protons across the membrane
IXO597_003145	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IXO597_003155	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IXO597_003160	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IXO597_003165	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IXO597_003215	COG1136	(ABC) transporter
IXO597_003220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IXO597_003225	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IXO597_003280	COG0339	signal peptide processing
IXO597_003320	COG1956	GAF domain-containing protein
IXO597_003325	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IXO597_003335	COG0720	synthase
IXO597_003340	COG0513	Belongs to the DEAD box helicase family
IXO597_003355	COG0625	glutathione transferase activity
IXO597_003385	COG0626	cystathionine gamma-synthase activity
IXO597_003405	COG0438	transferase activity, transferring glycosyl groups
IXO597_003405	COG1216	Glycosyl transferase, family 2
IXO597_003440	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
IXO597_003445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IXO597_003460	COG0277	FAD linked oxidase domain protein
IXO597_003465	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IXO597_003465	COG0546	phosphoglycolate phosphatase activity
IXO597_003480	COG2086	electron transfer activity
IXO597_003505	COG0662	Cupin 2, conserved barrel domain protein
IXO597_003505	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
IXO597_003510	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IXO597_003530	COG3039	Transposase
IXO597_003555	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IXO597_003555	COG3218	ABC-type transport auxiliary lipoprotein component
IXO597_003560	COG1127	ABC transporter
IXO597_003565	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IXO597_003580	COG0442	prolyl-tRNA aminoacylation
IXO597_003590	COG1183	phosphatidylcholine synthase activity
IXO597_003615	COG3039	Transposase
IXO597_003650	COG3039	Transposase
IXO597_003680	COG0525	valine-tRNA ligase activity
IXO597_003695	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IXO597_003705	COG0795	lipopolysaccharide-transporting ATPase activity
IXO597_003715	COG4974	Belongs to the 'phage' integrase family
IXO597_003720	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IXO597_003725	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IXO597_003725	COG0047	phosphoribosylformylglycinamidine synthase activity
IXO597_003730	COG5295	Hep Hag repeat protein
IXO597_003740	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IXO597_003750	COG1459	type II secretion system
IXO597_003755	COG2165	general secretion pathway protein
IXO597_003760	COG4970	Tfp pilus assembly protein FimT
IXO597_003765	COG2165	general secretion pathway protein
IXO597_003770	COG4795	General secretion pathway protein
IXO597_003775	COG3156	type II secretion system protein K
IXO597_003780	COG3166	PFAM Fimbrial assembly family protein
IXO597_003795	COG1450	Type ii and iii secretion system protein
IXO597_003805	COG2188	Transcriptional regulator
IXO597_003850	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IXO597_003855	COG1518	maintenance of DNA repeat elements
IXO597_003900	COG1399	metal-binding, possibly nucleic acid-binding protein
IXO597_003925	COG1028	Short-chain dehydrogenase reductase Sdr
IXO597_003930	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IXO597_003940	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IXO597_003945	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IXO597_003980	COG3829	transcription factor binding
IXO597_004055	COG3039	Transposase
IXO597_004060	COG0678	peroxiredoxin activity
IXO597_004080	COG0330	HflC and HflK could
IXO597_004085	COG0330	HflC and HflK could
IXO597_004100	COG0308	aminopeptidase N
IXO597_004125	COG3328	transposase activity
IXO597_004150	COG1560	Kdo2-lipid A biosynthetic process
IXO597_004155	COG1519	Transferase
IXO597_004170	COG1538	Outer membrane efflux protein
IXO597_004175	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IXO597_004200	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IXO597_004205	COG0066	3-isopropylmalate dehydratase activity
IXO597_004240	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IXO597_004250	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IXO597_004255	COG3710	Transcriptional regulator
IXO597_004280	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IXO597_004300	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
IXO597_004330	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IXO597_004340	COG3781	membrane
IXO597_004455	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
IXO597_004475	COG1217	gtp-binding protein TYPA
IXO597_004480	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IXO597_004490	COG0625	glutathione transferase activity
IXO597_004535	COG0446	pyridine nucleotide-disulphide oxidoreductase
IXO597_004535	COG1902	pentaerythritol trinitrate reductase activity
IXO597_004540	COG0604	alcohol dehydrogenase
IXO597_004565	COG0156	8-amino-7-oxononanoate synthase activity
IXO597_004570	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IXO597_004575	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IXO597_004580	COG4208	sulfate ABC transporter
IXO597_004585	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IXO597_004615	COG0406	alpha-ribazole phosphatase activity
IXO597_004625	COG0285	dihydrofolate synthase activity
IXO597_004645	COG2833	Protein of unknown function (DUF455)
IXO597_004660	COG3291	Pkd domain containing protein
IXO597_004670	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IXO597_004675	COG0671	phosphoesterase, PA-phosphatase related
IXO597_004680	COG0438	transferase activity, transferring glycosyl groups
IXO597_004690	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IXO597_004705	COG4783	chaperone-mediated protein folding
IXO597_004730	COG0473	3-isopropylmalate dehydrogenase activity
IXO597_004780	COG0544	peptidyl-prolyl cis-trans isomerase activity
IXO597_004820	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IXO597_004845	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IXO597_004855	COG0631	protein serine/threonine phosphatase activity
IXO597_004910	COG0582	viral genome integration into host DNA
IXO597_004920	COG0859	PFAM glycosyl transferase family 9
IXO597_004925	COG3642	lipopolysaccharide core region biosynthetic process
IXO597_004930	COG1234	tRNA 3'-trailer cleavage
IXO597_004935	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IXO597_004945	COG0315	cyclic pyranopterin monophosphate synthase activity
IXO597_004950	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IXO597_004955	COG0314	molybdopterin synthase activity
IXO597_004985	COG0537	adenosine 5'-monophosphoramidase activity
IXO597_005005	COG0714	Associated with various cellular activities
IXO597_005025	COG0242	peptide deformylase activity
IXO597_005085	COG3039	Transposase
IXO597_005115	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IXO597_005120	COG0726	polysaccharide deacetylase
IXO597_005170	COG2211	Major facilitator Superfamily
IXO597_005180	COG1609	Transcriptional regulator
IXO597_005185	COG1028	Short-chain dehydrogenase reductase Sdr
IXO597_005190	COG2851	Citrate transporter
IXO597_005210	COG0642	Histidine kinase
IXO597_005220	COG2197	response regulator
IXO597_005235	COG0583	DNA-binding transcription factor activity
IXO597_005250	COG4191	Histidine kinase
IXO597_005270	COG0281	malic enzyme
IXO597_005270	COG0280	phosphate acetyltransferase
IXO597_005295	COG0352	thiamine-phosphate diphosphorylase activity
IXO597_005300	COG1773	rubredoxin
IXO597_005305	COG2912	Transglutaminase-like superfamily
IXO597_005325	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IXO597_005350	COG0006	proline dipeptidase activity
IXO597_005385	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IXO597_005400	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IXO597_005405	COG1561	YicC-like family, N-terminal region
IXO597_005430	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IXO597_005440	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IXO597_005470	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
IXO597_005510	COG0714	Associated with various cellular activities
IXO597_005530	COG2304	oxidoreductase activity
IXO597_005550	COG1301	dicarboxylic acid transport
IXO597_005555	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IXO597_005565	COG0739	heme binding
IXO597_005570	COG1376	ErfK ybiS ycfS ynhG family protein
IXO597_005605	COG1028	Short-chain dehydrogenase reductase Sdr
IXO597_005620	COG0642	Histidine kinase
IXO597_005640	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IXO597_005645	COG4149	molybdate abc transporter
IXO597_005650	COG0725	ABC transporter, periplasmic molybdate-binding protein
IXO597_005655	COG3453	Protein conserved in bacteria
IXO597_005655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IXO597_005685	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IXO597_005695	COG3039	Transposase
IXO597_005725	COG2205	protein histidine kinase activity
IXO597_005730	COG0745	RESPONSE REGULATOR receiver
IXO597_005745	COG3039	Transposase
IXO597_005780	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IXO597_005785	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IXO597_005835	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IXO597_005930	COG2201	protein-glutamate methylesterase activity
IXO597_005995	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IXO597_006010	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IXO597_006025	COG1842	Phage shock protein A
IXO597_006050	COG0754	glutathionylspermidine amidase activity
IXO597_006110	COG0531	amino acid
IXO597_006115	COG2197	response regulator
IXO597_006130	COG1113	amino acid transport
IXO597_006160	COG1271	oxidase subunit
IXO597_006165	COG1294	oxidase, subunit
IXO597_006175	COG2239	Acts as a magnesium transporter
IXO597_006180	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IXO597_006185	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IXO597_006195	COG1660	Displays ATPase and GTPase activities
IXO597_006200	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IXO597_006205	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IXO597_006220	COG1137	ATPase activity
IXO597_006225	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IXO597_006235	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IXO597_006245	COG0271	Belongs to the BolA IbaG family
IXO597_006255	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IXO597_006275	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IXO597_006290	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IXO597_006300	COG0628	permease
IXO597_006310	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IXO597_006315	COG3178	'Phosphotransferase
IXO597_006330	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IXO597_006335	COG1555	photosystem II stabilization
IXO597_006380	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IXO597_006390	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IXO597_006415	COG0228	four-way junction DNA binding
IXO597_006420	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IXO597_006425	COG0336	Belongs to the RNA methyltransferase TrmD family
IXO597_006465	COG0534	Mate efflux family protein
IXO597_006490	COG0542	response to heat
IXO597_006525	COG4206	TonB-dependent receptor
IXO597_006585	COG0019	diaminopimelate decarboxylase activity
IXO597_006595	COG2814	Major facilitator Superfamily
IXO597_006600	COG4264	IucA IucC family
IXO597_006610	COG4772	TonB-dependent receptor
IXO597_006640	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IXO597_006640	COG4651	solute:proton antiporter activity
IXO597_006685	COG0488	(ABC) transporter
IXO597_006710	COG0657	acetylesterase activity
IXO597_006710	COG2755	lipolytic protein G-D-S-L family
IXO597_006740	COG2207	Transcriptional regulator
IXO597_006745	COG0326	Molecular chaperone. Has ATPase activity
IXO597_006770	COG3328	transposase activity
IXO597_006775	COG0174	glutamine synthetase
IXO597_006780	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
IXO597_006790	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IXO597_006805	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IXO597_006840	COG2146	nitrite reductase [NAD(P)H] activity
IXO597_006850	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IXO597_006855	COG0719	Fe-S assembly protein
IXO597_006860	COG0396	ATPase activity
IXO597_006865	COG0719	Fe-S assembly protein
IXO597_006870	COG1959	2 iron, 2 sulfur cluster binding
IXO597_006890	COG0693	protein deglycase activity
IXO597_006940	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IXO597_006970	COG0519	Catalyzes the synthesis of GMP from XMP
IXO597_006980	COG1678	Uncharacterized ACR, COG1678
IXO597_006985	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IXO597_007000	COG1764	response to oxidative stress
IXO597_007010	COG0384	phenazine biosynthesis protein PhzF
IXO597_007020	COG0527	aspartate kinase activity
IXO597_007045	COG0142	geranyltranstransferase activity
IXO597_007050	COG0629	single-stranded DNA binding
IXO597_007055	COG2203	Gaf domain
IXO597_007055	COG3706	GGDEF domain
IXO597_007055	COG4251	negative regulation of phosphorylation
IXO597_007055	COG5001	Diguanylate cyclase
IXO597_007090	COG2879	small protein
IXO597_007095	COG1966	Carbon starvation protein
IXO597_007100	COG1741	Belongs to the pirin family
IXO597_007185	COG3328	transposase activity
IXO597_007380	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
IXO597_007400	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
IXO597_007405	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
IXO597_007410	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
IXO597_007415	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
IXO597_007495	COG0587	DNA-directed DNA polymerase activity
IXO597_007510	COG1297	OPT oligopeptide transporter protein
IXO597_007535	COG0823	Involved in the tonB-independent uptake of proteins
IXO597_007535	COG1506	peptidase
IXO597_007555	COG1917	Cupin 2, conserved barrel domain protein
IXO597_007555	COG2207	Transcriptional regulator
IXO597_007575	COG0753	catalase activity
IXO597_007615	COG0469	pyruvate kinase activity
IXO597_007620	COG3588	fructose-bisphosphate aldolase
IXO597_007625	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
IXO597_007670	COG0784	Response regulator, receiver
IXO597_007670	COG2198	Histidine kinase
IXO597_007670	COG2205	protein histidine kinase activity
IXO597_007690	COG0175	sulfate reduction
IXO597_007695	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IXO597_007700	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IXO597_007705	COG0175	sulfate reduction
IXO597_007710	COG0529	Catalyzes the synthesis of activated sulfate
IXO597_007710	COG2895	sulfate adenylyltransferase (ATP) activity
IXO597_007720	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IXO597_007725	COG0308	aminopeptidase N
IXO597_007745	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IXO597_007770	COG1970	mechanosensitive ion channel activity
IXO597_007800	COG0471	metal ion transport
IXO597_007800	COG3273	potassium ion transport
IXO597_007810	COG2022	thiamine diphosphate biosynthetic process
IXO597_007935	COG3118	belongs to the thioredoxin family
IXO597_007960	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IXO597_007985	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IXO597_008010	COG2968	Membrane
IXO597_008025	COG3164	Protein of unknown function
IXO597_008035	COG0312	modulator of DNA gyrase
IXO597_008045	COG0312	modulator of DNA gyrase
IXO597_008070	COG0142	geranyltranstransferase activity
IXO597_008075	COG1722	exodeoxyribonuclease VII activity
IXO597_008080	COG0037	tRNA processing
IXO597_008085	COG1785	Belongs to the alkaline phosphatase family
IXO597_008090	COG1301	dicarboxylic acid transport
IXO597_008105	COG0791	NLP P60 protein
IXO597_008110	COG0791	NLP P60 protein
IXO597_008115	COG1047	Peptidyl-prolyl cis-trans
IXO597_008120	COG2311	Membrane
IXO597_008125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IXO597_008165	COG0489	protein tyrosine kinase activity
IXO597_008170	COG0717	Belongs to the dCTP deaminase family
IXO597_008190	COG0412	Dienelactone hydrolase
IXO597_008200	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IXO597_008245	COG2890	protein-(glutamine-N5) methyltransferase activity
IXO597_008250	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IXO597_008255	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IXO597_008260	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IXO597_008280	COG0101	tRNA pseudouridine synthase activity
IXO597_008285	COG0135	phosphoribosylanthranilate isomerase activity
IXO597_008310	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IXO597_008315	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IXO597_008360	COG0149	triose-phosphate isomerase activity
IXO597_008375	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IXO597_008385	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IXO597_008390	COG0649	NAD binding
IXO597_008395	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
IXO597_008400	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IXO597_008405	COG1034	ATP synthesis coupled electron transport
IXO597_008410	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
IXO597_008440	COG1007	ATP synthesis coupled electron transport
IXO597_008450	COG0779	Required for maturation of 30S ribosomal subunits
IXO597_008455	COG0195	Participates in both transcription termination and antitermination
IXO597_008460	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IXO597_008475	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IXO597_008480	COG1185	polyribonucleotide nucleotidyltransferase activity
IXO597_008515	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IXO597_008525	COG2095	MarC family integral membrane protein
IXO597_008530	COG3039	Transposase
IXO597_008550	COG1611	Belongs to the LOG family
IXO597_008590	COG4969	Belongs to the N-Me-Phe pilin family
IXO597_008630	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IXO597_008645	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IXO597_008700	COG0438	transferase activity, transferring glycosyl groups
IXO597_008705	COG0438	transferase activity, transferring glycosyl groups
IXO597_008715	COG0438	transferase activity, transferring glycosyl groups
IXO597_008760	COG3040	lipid binding
IXO597_008845	COG0784	Response regulator, receiver
IXO597_008845	COG4191	Histidine kinase
IXO597_008865	COG0552	protein localization to endoplasmic reticulum
IXO597_008875	COG3938	Belongs to the proline racemase family
IXO597_008880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IXO597_008895	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IXO597_008905	COG0006	proline dipeptidase activity
IXO597_008920	COG0531	amino acid
IXO597_008970	COG4206	TonB-dependent receptor
IXO597_009065	COG0746	molybdenum cofactor guanylyltransferase activity
IXO597_009095	COG1648	precorrin-2 dehydrogenase activity
IXO597_009095	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IXO597_009130	COG3039	Transposase
IXO597_009150	COG3039	Transposase
IXO597_009180	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IXO597_009200	COG1054	Belongs to the UPF0176 family
IXO597_009215	COG1530	ribonuclease E activity
IXO597_009225	COG3064	Membrane
IXO597_009230	COG0428	transporter
IXO597_009235	COG0428	transporter
IXO597_009315	COG3039	Transposase
IXO597_009425	COG0631	protein serine/threonine phosphatase activity
IXO597_009430	COG0515	serine threonine protein kinase
IXO597_009460	COG1858	cytochrome C peroxidase
IXO597_009510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IXO597_009515	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IXO597_009530	COG3039	Transposase
IXO597_009535	COG2801	Transposase and inactivated derivatives
IXO597_009565	COG2201	protein-glutamate methylesterase activity
IXO597_009590	COG2895	sulfate adenylyltransferase (ATP) activity
IXO597_009590	COG0529	Catalyzes the synthesis of activated sulfate
IXO597_009635	COG1981	membrane
IXO597_009660	COG1131	(ABC) transporter
IXO597_009665	COG4771	TonB-dependent receptor
IXO597_009675	COG0825	malonyl-CoA metabolic process
IXO597_009695	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IXO597_009700	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IXO597_009720	COG0750	zinc metalloprotease
IXO597_009725	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
IXO597_009730	COG0575	Belongs to the CDS family
IXO597_009740	COG0233	cytoplasmic translational termination
IXO597_009755	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IXO597_009815	COG1393	Belongs to the ArsC family
IXO597_009830	COG0367	asparagine synthase
IXO597_009840	COG4774	siderophore transport
IXO597_009880	COG1566	PFAM secretion protein HlyD family protein
IXO597_009885	COG2814	Major facilitator Superfamily
IXO597_009935	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IXO597_009945	COG1960	acyl-CoA dehydrogenase activity
IXO597_009970	COG2914	Belongs to the UPF0125 (RnfH) family
IXO597_009975	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IXO597_009985	COG0497	DNA recombination
IXO597_009995	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IXO597_010000	COG0443	Heat shock 70 kDa protein
IXO597_010005	COG0484	heat shock protein binding
IXO597_010010	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
IXO597_010015	COG0287	Prephenate dehydrogenase
IXO597_010015	COG1605	Chorismate mutase
IXO597_010030	COG0583	DNA-binding transcription factor activity
IXO597_010045	COG1132	(ABC) transporter
IXO597_010080	COG2850	peptidyl-arginine hydroxylation
IXO597_010165	COG1131	(ABC) transporter
IXO597_010170	COG1725	Transcriptional regulator
IXO597_010180	COG0386	Belongs to the glutathione peroxidase family
IXO597_010195	COG2900	Belongs to the SlyX family
IXO597_010210	COG1609	Transcriptional regulator
IXO597_010220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IXO597_010230	COG1410	methionine synthase
IXO597_010230	COG0646	methionine synthase
IXO597_010235	COG0646	methionine synthase
IXO597_010235	COG1410	methionine synthase
IXO597_010240	COG2226	methyltransferase
IXO597_010245	COG1960	acyl-CoA dehydrogenase activity
IXO597_010270	COG0557	exoribonuclease II activity
IXO597_010290	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IXO597_010300	COG3039	Transposase
IXO597_010310	COG3328	transposase activity
IXO597_010320	COG1278	Cold shock
IXO597_010410	COG3039	Transposase
IXO597_010440	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IXO597_010465	COG2166	iron-sulfur cluster assembly
IXO597_010480	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IXO597_010485	COG0137	argininosuccinate synthase activity
IXO597_010495	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IXO597_010500	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IXO597_010515	COG0165	Argininosuccinate lyase
IXO597_010570	COG1271	oxidase subunit
IXO597_010590	COG4988	ABC transporter
IXO597_010595	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IXO597_010685	COG3209	COG3209 Rhs family protein
IXO597_010700	COG3328	transposase activity
IXO597_010730	COG0643	Histidine kinase
IXO597_010730	COG0784	Response regulator, receiver
IXO597_010730	COG2198	Histidine kinase
IXO597_010785	COG1684	flagellar biosynthetic protein fliR
IXO597_010800	COG3190	flagellar
IXO597_010850	COG1677	Flagellar hook-basal body complex protein FliE
IXO597_010885	COG1028	Short-chain dehydrogenase reductase Sdr
IXO597_010895	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IXO597_010915	COG2201	protein-glutamate methylesterase activity
IXO597_010945	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IXO597_010950	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IXO597_010990	COG4787	bacterial-type flagellum-dependent cell motility
IXO597_011000	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
IXO597_011005	COG1558	bacterial-type flagellum-dependent cell motility
IXO597_011015	COG0784	Response regulator, receiver
IXO597_011015	COG0835	chemotaxis
IXO597_011035	COG5002	protein histidine kinase activity
IXO597_011045	COG4585	Histidine kinase
IXO597_011050	COG5001	Diguanylate cyclase
IXO597_011095	COG0542	response to heat
IXO597_011120	COG0492	ferredoxin-NADP+ reductase activity
IXO597_011125	COG1674	ftsk spoiiie
IXO597_011145	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IXO597_011165	COG0038	chloride channel
IXO597_011170	COG0183	Belongs to the thiolase family
IXO597_011175	COG1024	Enoyl-CoA hydratase
IXO597_011175	COG1250	3-hydroxyacyl-CoA dehydrogenase
IXO597_011190	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IXO597_011200	COG1426	Protein conserved in bacteria
IXO597_011210	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IXO597_011220	COG0303	'Molybdopterin
IXO597_011280	COG3039	Transposase
IXO597_011300	COG3039	Transposase
IXO597_011305	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IXO597_011325	COG0742	ribosomal rna small subunit methyltransferase
IXO597_011330	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IXO597_011340	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IXO597_011345	COG0405	Gamma-glutamyltransferase
IXO597_011425	COG0343	queuine tRNA-ribosyltransferase activity
IXO597_011430	COG1862	Preprotein translocase
IXO597_011440	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IXO597_011470	COG3328	transposase activity
IXO597_011480	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IXO597_011490	COG0704	Plays a role in the regulation of phosphate uptake
IXO597_011505	COG0573	inorganic phosphate transmembrane transporter activity
IXO597_011510	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IXO597_011545	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IXO597_011555	COG1024	Enoyl-CoA hydratase
IXO597_011565	COG0494	nUDIX hydrolase
IXO597_011610	COG0116	Belongs to the methyltransferase superfamily
IXO597_011610	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IXO597_011635	COG0667	Aldo Keto reductase
IXO597_011645	COG2925	Exonuclease
IXO597_011675	COG0288	reversible hydration of carbon dioxide
IXO597_011705	COG0316	Belongs to the HesB IscA family
IXO597_011710	COG0360	Binds together with S18 to 16S ribosomal RNA
IXO597_011720	COG0359	binds to the 23S rRNA
IXO597_011730	COG3115	cell septum assembly
IXO597_011745	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
IXO597_011760	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IXO597_011785	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IXO597_011795	COG2986	histidine ammonia-lyase
IXO597_011800	COG1228	amidohydrolase
IXO597_011840	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IXO597_011850	COG0077	Prephenate dehydratase
IXO597_011850	COG1605	Chorismate mutase
IXO597_011855	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IXO597_011865	COG3328	transposase activity
IXO597_011945	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IXO597_011970	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IXO597_011975	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IXO597_011975	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IXO597_011980	COG0802	atpase or kinase
IXO597_011985	COG0860	N-Acetylmuramoyl-L-alanine amidase
IXO597_011990	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IXO597_012010	COG1028	Short-chain dehydrogenase reductase Sdr
IXO597_012030	COG2081	HI0933 family
IXO597_012035	COG4681	YaeQ
IXO597_012040	COG1671	Belongs to the UPF0178 family
IXO597_012050	COG0625	glutathione transferase activity
IXO597_012060	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
IXO597_012070	COG0513	Belongs to the DEAD box helicase family
IXO597_012075	COG0488	(ABC) transporter
IXO597_012095	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IXO597_012100	COG0483	inositol monophosphate 1-phosphatase activity
IXO597_012115	COG5001	Diguanylate cyclase
IXO597_012115	COG3300	MHYT domain
IXO597_012120	COG1509	lysine 2,3-aminomutase activity
IXO597_012135	COG0402	S-adenosylhomocysteine deaminase activity
IXO597_012140	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IXO597_012165	COG4677	pectinesterase activity
IXO597_012195	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
IXO597_012205	COG0531	amino acid
IXO597_012210	COG0531	amino acid
IXO597_012220	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IXO597_012225	COG0277	FAD linked oxidase domain protein
IXO597_012290	COG0436	Aminotransferase
IXO597_012315	COG1187	pseudouridine synthase activity
IXO597_012320	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IXO597_012325	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IXO597_012330	COG2350	Protein conserved in bacteria
IXO597_012360	COG1175	transmembrane transport
IXO597_012365	COG0395	ABC-type sugar transport system, permease component
IXO597_012390	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IXO597_012400	COG2957	Belongs to the agmatine deiminase family
IXO597_012415	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IXO597_012420	COG0539	negative regulation of cytoplasmic translation
IXO597_012425	COG0776	regulation of translation
IXO597_012435	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
IXO597_012440	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IXO597_012450	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IXO597_012470	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IXO597_012485	COG3002	Belongs to the UPF0753 family
IXO597_012490	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IXO597_012495	COG0583	DNA-binding transcription factor activity
IXO597_012525	COG0583	DNA-binding transcription factor activity
IXO597_012545	COG1914	H( )-stimulated, divalent metal cation uptake system
IXO597_012565	COG0668	transmembrane transport
IXO597_012575	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
IXO597_012590	COG1028	Short-chain dehydrogenase reductase Sdr
IXO597_012595	COG1183	phosphatidylcholine synthase activity
IXO597_012605	COG3243	poly(R)-hydroxyalkanoic acid synthase
IXO597_012620	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IXO597_012620	COG0723	plastoquinol--plastocyanin reductase activity
IXO597_012630	COG2183	response to ionizing radiation
IXO597_012645	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
IXO597_012660	COG0671	phosphoesterase, PA-phosphatase related
IXO597_012690	COG1794	racemase activity, acting on amino acids and derivatives
IXO597_012695	COG0697	spore germination
IXO597_012720	COG1012	belongs to the aldehyde dehydrogenase family
IXO597_012760	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IXO597_012780	COG0124	histidyl-tRNA synthetase
IXO597_012800	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IXO597_012815	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IXO597_012815	COG0131	Imidazoleglycerol-phosphate dehydratase
IXO597_012825	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IXO597_012835	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IXO597_012835	COG0140	phosphoribosyl-ATP diphosphatase activity
IXO597_012880	COG0653	protein targeting
IXO597_012950	COG2801	Transposase and inactivated derivatives
IXO597_013000	COG0322	excinuclease ABC activity
IXO597_013010	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IXO597_013020	COG1663	tetraacyldisaccharide 4'-kinase activity
IXO597_013035	COG0811	peptide transport
IXO597_013060	COG4591	ABC-type transport system involved in lipoprotein release permease component
IXO597_013075	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IXO597_013090	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IXO597_013105	COG0354	folic acid binding
IXO597_013120	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IXO597_013130	COG0363	glucosamine-6-phosphate deaminase activity
IXO597_013135	COG0129	dihydroxy-acid dehydratase activity
IXO597_013140	COG0800	Aldolase
IXO597_013170	COG2205	protein histidine kinase activity
IXO597_013170	COG5002	protein histidine kinase activity
IXO597_013170	COG0784	Response regulator, receiver
IXO597_013205	COG3328	transposase activity
IXO597_013220	COG3039	Transposase
IXO597_013230	COG3328	transposase activity
IXO597_013270	COG0386	Belongs to the glutathione peroxidase family
IXO597_013355	COG2203	Gaf domain
IXO597_013355	COG5001	Diguanylate cyclase
IXO597_013355	COG4251	negative regulation of phosphorylation
IXO597_013355	COG3706	GGDEF domain
IXO597_013375	COG1472	Belongs to the glycosyl hydrolase 3 family
IXO597_013430	COG1469	GTP cyclohydrolase I activity
IXO597_013435	COG0860	N-Acetylmuramoyl-L-alanine amidase
IXO597_013470	COG3039	Transposase
IXO597_013500	COG4566	intracellular signal transduction
IXO597_013560	COG2969	positive regulation of protein catabolic process
IXO597_013565	COG0625	glutathione transferase activity
IXO597_013570	COG2857	Cytochrome c1
IXO597_013575	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IXO597_013580	COG0723	plastoquinol--plastocyanin reductase activity
IXO597_013585	COG0741	lytic transglycosylase activity
IXO597_013610	COG1702	phosphate starvation-inducible protein PhoH
IXO597_013630	COG4535	Mg2 and Co2 transporter CorC
IXO597_013645	COG1012	belongs to the aldehyde dehydrogenase family
IXO597_013655	COG1177	transmembrane transport
IXO597_013665	COG3842	ATPase activity
IXO597_013710	COG0174	glutamine synthetase
IXO597_013715	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IXO597_013725	COG0477	Major facilitator Superfamily
IXO597_013735	COG0243	molybdopterin cofactor binding
IXO597_013745	COG2223	nitrite transmembrane transporter activity
IXO597_013755	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IXO597_013760	COG1121	(ABC) transporter
IXO597_013770	COG2733	membrane
IXO597_013775	COG2205	protein histidine kinase activity
IXO597_013775	COG0784	Response regulator, receiver
IXO597_013775	COG5002	protein histidine kinase activity
IXO597_013790	COG3039	Transposase
IXO597_013795	COG2902	Dehydrogenase
IXO597_013805	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IXO597_013810	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IXO597_013830	COG1609	Transcriptional regulator
IXO597_013835	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IXO597_013835	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IXO597_013840	COG1105	Belongs to the carbohydrate kinase PfkB family
IXO597_013845	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IXO597_013845	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IXO597_013860	COG3039	Transposase
IXO597_013865	COG3328	transposase activity
IXO597_013895	COG3039	Transposase
IXO597_013985	COG4771	TonB-dependent receptor
IXO597_013995	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IXO597_014015	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IXO597_014020	COG1360	Flagellar Motor Protein
IXO597_014030	COG0835	chemotaxis
IXO597_014040	COG0745	RESPONSE REGULATOR receiver
IXO597_014060	COG0840	transmembrane signaling receptor activity
IXO597_014070	COG0840	transmembrane signaling receptor activity
IXO597_014085	COG0840	transmembrane signaling receptor activity
IXO597_014095	COG0840	transmembrane signaling receptor activity
IXO597_014100	COG0840	transmembrane signaling receptor activity
IXO597_014105	COG0840	transmembrane signaling receptor activity
IXO597_014110	COG0840	transmembrane signaling receptor activity
IXO597_014130	COG0835	chemotaxis
IXO597_014150	COG0840	transmembrane signaling receptor activity
IXO597_014180	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IXO597_014210	COG0318	PFAM AMP-dependent synthetase and ligase
IXO597_014215	COG1024	Enoyl-CoA hydratase
IXO597_014220	COG0784	Response regulator, receiver
IXO597_014220	COG2198	Histidine kinase
IXO597_014220	COG2205	protein histidine kinase activity
IXO597_014310	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IXO597_014320	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IXO597_014325	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IXO597_014335	COG0505	Belongs to the CarA family
IXO597_014340	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IXO597_014350	COG2258	MOSC domain
IXO597_014355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IXO597_014405	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IXO597_014425	COG0477	Major facilitator Superfamily
IXO597_014435	COG1070	Carbohydrate kinase
IXO597_014445	COG1501	Belongs to the glycosyl hydrolase 31 family
IXO597_014460	COG0800	Aldolase
IXO597_014465	COG4948	Mandelate Racemase Muconate Lactonizing
IXO597_014475	COG3734	2-keto-3-deoxy-galactonokinase
IXO597_014480	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IXO597_014490	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IXO597_014505	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IXO597_014510	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
IXO597_014520	COG0351	phosphomethylpyrimidine kinase
IXO597_014550	COG0583	DNA-binding transcription factor activity
IXO597_014555	COG1741	Belongs to the pirin family
IXO597_014575	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IXO597_014580	COG0305	Participates in initiation and elongation during chromosome replication
IXO597_014605	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IXO597_014610	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IXO597_014615	COG2137	regulation of response to DNA damage stimulus
IXO597_014620	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IXO597_014635	COG1546	Belongs to the CinA family
IXO597_014640	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IXO597_014655	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IXO597_014665	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
IXO597_014670	COG1534	Rna-binding protein
IXO597_014685	COG1238	metal cluster binding
IXO597_014690	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IXO597_014695	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
IXO597_014700	COG2840	Smr protein MutS2
IXO597_014710	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
IXO597_014720	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
IXO597_014725	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IXO597_014730	COG0148	phosphopyruvate hydratase activity
IXO597_014740	COG2877	3-deoxy-8-phosphooctulonate synthase activity
IXO597_014745	COG0504	CTP synthase activity
IXO597_014765	COG1434	Gram-negative-bacterium-type cell wall biogenesis
IXO597_014770	COG0306	phosphate transporter
IXO597_014780	COG1253	flavin adenine dinucleotide binding
IXO597_014795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IXO597_014815	COG0477	Major facilitator Superfamily
IXO597_014830	COG1132	(ABC) transporter
IXO597_014835	COG1136	(ABC) transporter
IXO597_014850	COG0438	transferase activity, transferring glycosyl groups
IXO597_014860	COG2264	protein methyltransferase activity
IXO597_014885	COG1216	Glycosyl transferase, family 2
IXO597_014885	COG1442	glycosyl transferase family 8
IXO597_014890	COG2244	polysaccharide biosynthetic process
IXO597_014940	COG1595	DNA-templated transcription, initiation
IXO597_014955	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IXO597_014975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IXO597_015005	COG2201	protein-glutamate methylesterase activity
IXO597_015025	COG0583	DNA-binding transcription factor activity
IXO597_015035	COG3039	Transposase
IXO597_015075	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IXO597_015090	COG2040	homocysteine
IXO597_015095	COG0833	amino acid
IXO597_015115	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IXO597_015115	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IXO597_015125	COG2878	Part of a membrane complex involved in electron transport
IXO597_015140	COG1595	DNA-templated transcription, initiation
IXO597_015165	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IXO597_015180	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IXO597_015185	COG0251	oxidation-reduction process
IXO597_015195	COG0392	lysyltransferase activity
IXO597_015195	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IXO597_015240	COG2814	Major facilitator Superfamily
IXO597_015245	COG1902	pentaerythritol trinitrate reductase activity
IXO597_015255	COG2824	Alkylphosphonate utilization operon protein PhnA
IXO597_015270	COG1047	Peptidyl-prolyl cis-trans
IXO597_015320	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IXO597_015335	COG1451	nucleotide metabolic process
IXO597_015360	COG0183	Belongs to the thiolase family
IXO597_015390	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
IXO597_015390	COG1793	dna ligase
IXO597_015400	COG1793	dna ligase
IXO597_015405	COG1201	RNA secondary structure unwinding
IXO597_015425	COG1278	Cold shock
IXO597_015430	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IXO597_015435	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
IXO597_015445	COG3046	protein related to deoxyribodipyrimidine photolyase
IXO597_015450	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
IXO597_015455	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IXO597_015475	COG2954	triphosphatase activity
IXO597_015490	COG1381	Involved in DNA repair and RecF pathway recombination
IXO597_015520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IXO597_015535	COG1250	3-hydroxyacyl-CoA dehydrogenase
IXO597_015535	COG1024	Enoyl-CoA hydratase
IXO597_015555	COG1024	Enoyl-CoA hydratase
IXO597_015560	COG1960	acyl-CoA dehydrogenase activity
IXO597_015630	COG2353	YceI-like domain
IXO597_015640	COG2353	YceI-like domain
IXO597_015655	COG1760	l-serine dehydratase
IXO597_015665	COG0626	cystathionine gamma-synthase activity
IXO597_015670	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IXO597_015675	COG0739	heme binding
IXO597_015685	COG1272	protein, Hemolysin III
IXO597_015705	COG0463	Glycosyl transferase, family 2
IXO597_015715	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IXO597_015725	COG4771	TonB-dependent receptor
IXO597_015730	COG1309	transcriptional regulator
IXO597_015740	COG1960	acyl-CoA dehydrogenase activity
IXO597_015775	COG0509	glycine decarboxylation via glycine cleavage system
IXO597_015790	COG0330	HflC and HflK could
IXO597_015805	COG3956	TIGRFAM MazG family protein
IXO597_015815	COG0494	nUDIX hydrolase
IXO597_015825	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IXO597_015830	COG0837	glucose binding
IXO597_015845	COG1388	LysM domain
IXO597_015845	COG3858	chitin binding
IXO597_015865	COG1472	Belongs to the glycosyl hydrolase 3 family
IXO597_015920	COG3328	transposase activity
IXO597_015935	COG3537	Alpha-1,2-mannosidase
IXO597_015980	COG1446	asparaginase
IXO597_016025	COG0784	Response regulator, receiver
IXO597_016025	COG2198	Histidine kinase
IXO597_016025	COG0643	Histidine kinase
IXO597_016030	COG0840	transmembrane signaling receptor activity
IXO597_016035	COG0835	chemotaxis
IXO597_016050	COG0189	ligase activity
IXO597_016060	COG1397	ADP-ribosylglycohydrolase
IXO597_016070	COG1199	ATP-dependent helicase activity
IXO597_016080	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IXO597_016085	COG1215	transferase activity, transferring glycosyl groups
IXO597_016095	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IXO597_016115	COG0535	radical SAM domain protein
IXO597_016120	COG0535	radical SAM domain protein
IXO597_016145	COG1643	Atp-dependent helicase
IXO597_016150	COG0783	Belongs to the Dps family
IXO597_016155	COG3039	Transposase
IXO597_016160	COG0514	ATP-dependent DNA helicase (RecQ)
IXO597_016185	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IXO597_016215	COG0840	transmembrane signaling receptor activity
IXO597_016230	COG1187	pseudouridine synthase activity
IXO597_016240	COG0602	queuosine metabolic process
IXO597_016250	COG2885	chlorophyll binding
IXO597_016265	COG0848	biopolymer transport protein
IXO597_016275	COG0824	Thioesterase
IXO597_016280	COG2255	four-way junction helicase activity
IXO597_016290	COG0632	four-way junction helicase activity
IXO597_016415	COG3209	COG3209 Rhs family protein
IXO597_016435	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IXO597_016440	COG1845	cytochrome c oxidase, subunit III
IXO597_016445	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IXO597_016460	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IXO597_016465	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IXO597_016475	COG0196	riboflavin kinase activity
IXO597_016480	COG0728	peptidoglycan biosynthetic process
IXO597_016485	COG0268	Binds directly to 16S ribosomal RNA
IXO597_016490	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IXO597_016495	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IXO597_016505	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IXO597_016510	COG0824	Thioesterase
IXO597_016525	COG1946	Acyl-CoA thioesterase
IXO597_016535	COG1595	DNA-templated transcription, initiation
IXO597_016550	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
IXO597_016590	COG1877	trehalose-phosphatase activity
IXO597_016595	COG3387	PFAM Glycoside hydrolase 15-related
IXO597_016620	COG0564	pseudouridine synthase activity
IXO597_016625	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IXO597_016630	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IXO597_016630	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IXO597_016640	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IXO597_016645	COG0045	succinate-CoA ligase (ADP-forming) activity
IXO597_016670	COG2184	nucleotidyltransferase activity
IXO597_016690	COG2194	sulfuric ester hydrolase activity
IXO597_016695	COG4969	Belongs to the N-Me-Phe pilin family
IXO597_016705	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
IXO597_016720	COG3328	transposase activity
IXO597_016735	COG3209	COG3209 Rhs family protein
IXO597_016750	COG3039	Transposase
IXO597_016765	COG3039	Transposase
IXO597_016780	COG1132	(ABC) transporter
IXO597_016810	COG0745	RESPONSE REGULATOR receiver
IXO597_016815	COG5000	phosphorelay sensor kinase activity
IXO597_016815	COG5002	protein histidine kinase activity
IXO597_016820	COG0475	glutathione-regulated potassium exporter activity
IXO597_016830	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IXO597_016850	COG1187	pseudouridine synthase activity
IXO597_016855	COG5002	protein histidine kinase activity
IXO597_016855	COG5001	Diguanylate cyclase
IXO597_016970	COG0415	Belongs to the DNA photolyase family
IXO597_016975	COG0305	Participates in initiation and elongation during chromosome replication
IXO597_016985	COG0367	asparagine synthase
IXO597_017000	COG1960	acyl-CoA dehydrogenase activity
IXO597_017015	COG0084	hydrolase, TatD family'
IXO597_017020	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IXO597_017080	COG0735	belongs to the Fur family
IXO597_017085	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IXO597_017150	COG3039	Transposase
IXO597_017160	COG3039	Transposase
IXO597_017185	COG2205	protein histidine kinase activity
IXO597_017195	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IXO597_017205	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IXO597_017220	COG0643	Histidine kinase
IXO597_017220	COG2198	Histidine kinase
IXO597_017225	COG0840	transmembrane signaling receptor activity
IXO597_017230	COG0835	chemotaxis
IXO597_017235	COG2202	Pas domain
IXO597_017235	COG2200	EAL domain
IXO597_017235	COG2199	diguanylate cyclase activity
IXO597_017240	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IXO597_017255	COG3590	peptidase
IXO597_017275	COG1515	deoxyribonuclease V activity
IXO597_017285	COG1741	Belongs to the pirin family
IXO597_017430	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IXO597_017445	COG2197	response regulator
IXO597_017450	COG4585	Histidine kinase
IXO597_017470	COG2894	cell division
IXO597_017475	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
IXO597_017485	COG0642	Histidine kinase
IXO597_017490	COG0745	RESPONSE REGULATOR receiver
IXO597_017495	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IXO597_017505	COG2194	sulfuric ester hydrolase activity
IXO597_017535	COG3551	Protein conserved in bacteria
IXO597_017605	COG0203	ribosomal protein L17
IXO597_017615	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IXO597_017620	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IXO597_017630	COG0201	protein transport
IXO597_017640	COG1841	ribosomal large subunit assembly
IXO597_017670	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IXO597_017680	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IXO597_017685	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IXO597_017690	COG0255	Belongs to the universal ribosomal protein uL29 family
IXO597_017695	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IXO597_017705	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IXO597_017720	COG0089	rRNA binding
IXO597_017725	COG0088	Forms part of the polypeptide exit tunnel
IXO597_017730	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IXO597_017735	COG0051	transcription antitermination factor activity, RNA binding
IXO597_017755	COG0049	tRNA binding
IXO597_017760	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IXO597_017765	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IXO597_017770	COG0085	RNA polymerase activity
IXO597_017775	COG0222	ribosome binding
IXO597_017780	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IXO597_017790	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IXO597_017795	COG0250	Participates in transcription elongation, termination and antitermination
IXO597_017800	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IXO597_017830	COG0012	GTP binding
IXO597_017835	COG0193	aminoacyl-tRNA hydrolase activity
IXO597_017845	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IXO597_017860	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
IXO597_017875	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IXO597_017885	COG0521	Mo-molybdopterin cofactor biosynthetic process
IXO597_017905	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IXO597_017910	COG1295	ribonuclease BN
IXO597_017940	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IXO597_017950	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IXO597_017975	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
IXO597_018000	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
IXO597_018015	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IXO597_018015	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IXO597_018065	COG2890	protein-(glutamine-N5) methyltransferase activity
IXO597_018075	COG3634	alkyl hydroperoxide reductase activity
IXO597_018080	COG0583	DNA-binding transcription factor activity
IXO597_018085	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IXO597_018090	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IXO597_018125	COG2197	response regulator
IXO597_018200	COG3386	PFAM SMP-30 Gluconolaconase
IXO597_018220	COG1024	Enoyl-CoA hydratase
IXO597_018230	COG0318	PFAM AMP-dependent synthetase and ligase
IXO597_018235	COG0583	DNA-binding transcription factor activity
IXO597_018275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IXO597_018280	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IXO597_018290	COG2096	Adenosyltransferase
IXO597_018295	COG0123	including yeast histone deacetylase and acetoin utilization protein
IXO597_018310	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IXO597_018320	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IXO597_018325	COG2967	ApaG domain
IXO597_018350	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IXO597_018370	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IXO597_018390	COG0642	Histidine kinase
IXO597_018405	COG4181	ATPase activity
IXO597_018415	COG2175	clavaminate synthase activity
IXO597_018425	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
IXO597_018465	COG0667	Aldo Keto reductase
IXO597_018475	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IXO597_018480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IXO597_018490	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IXO597_018505	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IXO597_018540	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IXO597_018545	COG2226	methyltransferase
IXO597_018595	COG0604	alcohol dehydrogenase
IXO597_018595	COG3321	synthase
IXO597_018595	COG1028	Short-chain dehydrogenase reductase Sdr
IXO597_018605	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IXO597_018620	COG0494	nUDIX hydrolase
IXO597_018635	COG1388	LysM domain
IXO597_018635	COG4942	peptidase
IXO597_018645	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
IXO597_018660	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IXO597_018665	COG1181	Belongs to the D-alanine--D-alanine ligase family
IXO597_018670	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IXO597_018690	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IXO597_018705	COG3116	cell division
IXO597_018710	COG0275	rRNA processing
IXO597_018745	COG0792	nuclease activity
IXO597_018750	COG1988	membrane-bound metal-dependent
IXO597_018755	COG0277	FAD linked oxidase domain protein
IXO597_018760	COG0745	RESPONSE REGULATOR receiver
IXO597_018765	COG2205	protein histidine kinase activity
IXO597_018775	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
IXO597_018780	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IXO597_018805	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IXO597_018810	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IXO597_018815	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
IXO597_018835	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IXO597_018835	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IXO597_018855	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IXO597_018875	COG0488	(ABC) transporter
IXO597_018925	COG2205	protein histidine kinase activity
IXO597_018960	COG2205	protein histidine kinase activity
IXO597_018975	COG0218	Necessary for normal cell division and for the maintenance of normal septation
IXO597_019010	COG3039	Transposase
IXO597_019090	COG0726	polysaccharide deacetylase
IXO597_019090	COG1649	PFAM Uncharacterised BCR, COG1649
IXO597_019095	COG1215	transferase activity, transferring glycosyl groups
IXO597_019105	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IXO597_019110	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IXO597_019115	COG1609	Transcriptional regulator
IXO597_019125	COG2188	Transcriptional regulator
IXO597_019140	COG3250	beta-galactosidase activity
IXO597_019180	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IXO597_019185	COG4191	Histidine kinase
IXO597_019190	COG0784	Response regulator, receiver
IXO597_019195	COG4251	negative regulation of phosphorylation
IXO597_019200	COG2823	Periplasmic or secreted lipoprotein
IXO597_019205	COG0673	inositol 2-dehydrogenase activity
IXO597_019210	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
IXO597_019245	COG1051	belongs to the nudix hydrolase family
IXO597_019245	COG1056	cytidyltransferase-related domain
IXO597_019285	COG2921	Belongs to the UPF0250 family
IXO597_019295	COG1686	Belongs to the peptidase S11 family
IXO597_019300	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IXO597_019305	COG2951	lytic endotransglycosylase activity
IXO597_019360	COG0772	Belongs to the SEDS family
IXO597_019375	COG1792	Involved in formation and maintenance of cell shape
IXO597_019380	COG1077	Cell shape determining protein MreB Mrl
IXO597_019385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IXO597_019430	COG2199	diguanylate cyclase activity
IXO597_019435	COG0308	aminopeptidase N
IXO597_019470	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IXO597_019500	COG0436	Aminotransferase
IXO597_019515	COG1505	serine-type exopeptidase activity
IXO597_019540	COG0181	hydroxymethylbilane synthase activity
IXO597_019550	COG3275	phosphorelay sensor kinase activity
IXO597_019585	COG0659	secondary active sulfate transmembrane transporter activity
IXO597_019590	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IXO597_019590	COG5297	Belongs to the glycosyl hydrolase family 6
IXO597_019660	COG0598	Magnesium transport protein CorA
IXO597_019670	COG1113	amino acid transport
IXO597_019675	COG5297	Belongs to the glycosyl hydrolase family 6
IXO597_019680	COG4305	rare lipoprotein A
IXO597_019685	COG0697	spore germination
IXO597_019740	COG4221	oxidoreductase activity
IXO597_019770	COG0456	acetyltransferase
IXO597_019780	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IXO597_019815	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IXO597_019815	COG2111	Na H antiporter
IXO597_019820	COG1006	Multisubunit Na H antiporter MnhC subunit
IXO597_019825	COG0651	ATP synthesis coupled electron transport
IXO597_019835	COG2212	antiporter activity
IXO597_019840	COG1320	monovalent cation:proton antiporter activity
IXO597_019870	COG3104	oligopeptide transport
IXO597_019875	COG3483	tryptophan 2,3-dioxygenase activity
IXO597_019885	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IXO597_019925	COG0183	Belongs to the thiolase family
IXO597_019995	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
IXO597_020000	COG3023	N-Acetylmuramoyl-L-alanine amidase
IXO597_020010	COG4948	Mandelate Racemase Muconate Lactonizing
IXO597_020035	COG0531	amino acid
IXO597_020060	COG4682	membrane
IXO597_020065	COG2133	pyrroloquinoline quinone binding
IXO597_020130	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IXO597_020135	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IXO597_020145	COG1610	YqeY-like protein
IXO597_020155	COG1295	ribonuclease BN
IXO597_020160	COG0358	DNA primase activity
IXO597_020225	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
IXO597_020240	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IXO597_020290	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IXO597_020295	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IXO597_020300	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
IXO597_020310	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
IXO597_020315	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IXO597_020330	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IXO597_020390	COG3328	transposase activity
IXO597_020395	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IXO597_020395	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IXO597_020405	COG1473	amidohydrolase
IXO597_020410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IXO597_020415	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IXO597_020430	COG5383	Protein conserved in bacteria
IXO597_020460	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IXO597_020465	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
IXO597_020480	COG0028	Belongs to the TPP enzyme family
IXO597_020485	COG4191	Histidine kinase
IXO597_020510	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IXO597_020525	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IXO597_020530	COG3177	Filamentation induced by cAMP protein fic
IXO597_020545	COG0596	Alpha beta hydrolase
IXO597_020550	COG0727	PFAM Uncharacterised protein family (UPF0153)
IXO597_020555	COG0318	PFAM AMP-dependent synthetase and ligase
IXO597_020560	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IXO597_020575	COG3039	Transposase
IXO597_020595	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IXO597_020605	COG0129	dihydroxy-acid dehydratase activity
IXO597_020635	COG3039	Transposase
IXO597_020645	COG0408	coproporphyrinogen oxidase activity
IXO597_020690	COG3039	Transposase
IXO597_020740	COG2353	YceI-like domain
IXO597_020770	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IXO597_020785	COG3386	PFAM SMP-30 Gluconolaconase
IXO597_020830	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IXO597_020845	COG4771	TonB-dependent receptor
IXO597_020855	COG0459	protein refolding
IXO597_020880	COG1252	NADH dehydrogenase
IXO597_020890	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IXO597_020895	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IXO597_020900	COG3437	response regulator, receiver
IXO597_020905	COG2177	Part of the ABC transporter FtsEX involved in
IXO597_020910	COG2884	Cell division ATP-binding protein ftsE
IXO597_020920	COG3118	belongs to the thioredoxin family
IXO597_020925	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IXO597_020940	COG0729	surface antigen
IXO597_020945	COG2911	Protein conserved in bacteria
IXO597_020980	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IXO597_020995	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IXO597_021045	COG1733	regulation of RNA biosynthetic process
IXO597_021050	COG0702	epimerase
IXO597_021080	COG0583	DNA-binding transcription factor activity
IXO597_021085	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IXO597_021105	COG0745	RESPONSE REGULATOR receiver
IXO597_021135	COG1902	pentaerythritol trinitrate reductase activity
IXO597_021140	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IXO597_021150	COG2814	Major facilitator Superfamily
IXO597_021155	COG0583	DNA-binding transcription factor activity
IXO597_021170	COG0084	hydrolase, TatD family'
IXO597_021240	COG3039	Transposase
IXO597_021280	COG3328	transposase activity
IXO597_021320	COG4770	biotin carboxylase activity
IXO597_021325	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IXO597_021330	COG1960	acyl-CoA dehydrogenase activity
IXO597_021385	COG0523	cobalamin synthesis protein
IXO597_021405	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IXO597_021420	COG4771	TonB-dependent receptor
IXO597_021425	COG0457	Tetratricopeptide repeat
IXO597_021435	COG0752	glycyl-tRNA synthetase alpha subunit
IXO597_021440	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IXO597_021465	COG0519	Catalyzes the synthesis of GMP from XMP
IXO597_021465	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IXO597_021475	COG0805	protein transport
IXO597_021485	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IXO597_021495	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
IXO597_021520	COG2974	May be involved in recombination
IXO597_021525	COG0037	tRNA processing
IXO597_021540	COG3661	Belongs to the glycosyl hydrolase 67 family
IXO597_021550	COG4948	Mandelate Racemase Muconate Lactonizing
IXO597_021560	COG1472	Belongs to the glycosyl hydrolase 3 family
IXO597_021565	COG0246	Mannitol dehydrogenase
IXO597_021590	COG3693	PFAM glycoside hydrolase, family 10
IXO597_021610	COG2211	Major facilitator Superfamily
IXO597_021655	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IXO597_021695	COG1846	Transcriptional regulator
IXO597_021700	COG1764	response to oxidative stress
IXO597_021765	COG3549	Plasmid maintenance system killer
IXO597_021775	COG1074	ATP-dependent DNA helicase activity
IXO597_021780	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IXO597_021830	COG2032	superoxide dismutase activity
IXO597_021835	COG2032	superoxide dismutase activity
IXO597_021840	COG2204	response regulator
IXO597_021845	COG3852	Histidine kinase
IXO597_021850	COG0004	ammonium transporteR
IXO597_021855	COG0347	Belongs to the P(II) protein family
IXO597_021860	COG0174	glutamine synthetase
IXO597_021865	COG1968	undecaprenyl-diphosphatase activity
IXO597_021910	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IXO597_021920	COG2062	phosphohistidine phosphatase, SixA
IXO597_021925	COG0489	protein tyrosine kinase activity
IXO597_021945	COG1396	sequence-specific DNA binding
IXO597_021950	COG3550	peptidyl-serine autophosphorylation
IXO597_021955	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
IXO597_021960	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IXO597_021985	COG0517	IMP dehydrogenase activity
IXO597_021985	COG1125	glycine betaine transport
IXO597_022000	COG1119	ATPase activity
IXO597_022010	COG1752	Esterase of the alpha-beta hydrolase superfamily
IXO597_022060	COG3328	transposase activity
IXO597_022080	COG3321	synthase
IXO597_022080	COG0604	alcohol dehydrogenase
IXO597_022080	COG1028	Short-chain dehydrogenase reductase Sdr
IXO597_022085	COG2937	Belongs to the GPAT DAPAT family
IXO597_022120	COG0284	orotidine-5'-phosphate decarboxylase activity
IXO597_022125	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
IXO597_022130	COG3132	Protein of unknown function, DUF480
IXO597_022145	COG0210	DNA helicase
IXO597_022160	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
IXO597_022195	COG1028	Short-chain dehydrogenase reductase Sdr
IXO597_022220	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IXO597_022300	COG1166	arginine decarboxylase activity
IXO597_022305	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IXO597_022320	COG3328	transposase activity
IXO597_022365	COG0606	chelatase, subunit chli
IXO597_022380	COG3039	Transposase
IXO597_022425	COG1127	ABC transporter
IXO597_022430	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IXO597_022435	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IXO597_022450	COG2853	Lipoprotein
IXO597_022475	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IXO597_022560	COG0676	glucose-6-phosphate 1-epimerase activity
IXO597_022585	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IXO597_022595	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IXO597_022605	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IXO597_022610	COG1064	alcohol dehydrogenase
IXO597_022660	COG1522	sequence-specific DNA binding
IXO597_022665	COG3186	Phenylalanine-4-hydroxylase
IXO597_022680	COG2755	lipolytic protein G-D-S-L family
IXO597_022710	COG0656	L-ascorbic acid biosynthetic process
IXO597_022715	COG2130	NADP-dependent
IXO597_022720	COG0667	Aldo Keto reductase
IXO597_022730	COG1187	pseudouridine synthase activity
IXO597_022740	COG1643	Atp-dependent helicase
IXO597_022745	COG4807	Protein conserved in bacteria
IXO597_022750	COG4948	Mandelate Racemase Muconate Lactonizing
IXO597_022755	COG0179	Fumarylacetoacetate (FAA) hydrolase
IXO597_022760	COG1028	Short-chain dehydrogenase reductase Sdr
IXO597_022780	COG3507	Belongs to the glycosyl hydrolase 43 family
IXO597_022820	COG3162	membrane
IXO597_022825	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IXO597_022840	COG0708	Exodeoxyribonuclease III
IXO597_022855	COG2091	lysine biosynthetic process via aminoadipic acid
IXO597_022865	COG3540	Alkaline phosphatase
IXO597_022870	COG0357	Ribosomal RNA small subunit methyltransferase G
IXO597_022895	COG2159	amidohydrolase
IXO597_022905	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IXO597_022910	COG0583	DNA-binding transcription factor activity
IXO597_022915	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IXO597_022930	COG0210	DNA helicase
IXO597_022945	COG0531	amino acid
IXO597_022950	COG1322	Protein conserved in bacteria
IXO597_022960	COG0386	Belongs to the glutathione peroxidase family
IXO597_023010	COG0793	Belongs to the peptidase S41A family
IXO597_023015	COG4942	peptidase
IXO597_023025	COG2234	aminopeptidase activity
IXO597_023070	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IXO597_023075	COG0302	gtp cyclohydrolase
IXO597_023095	COG0477	Major facilitator Superfamily
IXO597_023105	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IXO597_023165	COG1929	Belongs to the glycerate kinase type-1 family
IXO597_023170	COG2271	Major facilitator Superfamily
IXO597_023185	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IXO597_023190	COG0861	Integral membrane protein TerC family
IXO597_023200	COG0584	glycerophosphoryl diester phosphodiesterase
IXO597_023210	COG0671	phosphoesterase, PA-phosphatase related
IXO597_023215	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IXO597_023220	COG0726	polysaccharide deacetylase