locus-tag	class	description
IXO630_000005	COG2201	protein-glutamate methylesterase activity
IXO630_000035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IXO630_000055	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IXO630_000070	COG1595	DNA-templated transcription, initiation
IXO630_000120	COG2244	polysaccharide biosynthetic process
IXO630_000150	COG2264	protein methyltransferase activity
IXO630_000160	COG0438	transferase activity, transferring glycosyl groups
IXO630_000175	COG1136	(ABC) transporter
IXO630_000180	COG1132	(ABC) transporter
IXO630_000190	COG0477	Major facilitator Superfamily
IXO630_000200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IXO630_000215	COG1253	flavin adenine dinucleotide binding
IXO630_000225	COG0306	phosphate transporter
IXO630_000255	COG0504	CTP synthase activity
IXO630_000260	COG2877	3-deoxy-8-phosphooctulonate synthase activity
IXO630_000270	COG0148	phosphopyruvate hydratase activity
IXO630_000275	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IXO630_000280	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
IXO630_000290	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
IXO630_000300	COG2840	Smr protein MutS2
IXO630_000305	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
IXO630_000310	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IXO630_000315	COG1238	metal cluster binding
IXO630_000330	COG1534	Rna-binding protein
IXO630_000335	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
IXO630_000345	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IXO630_000350	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IXO630_000360	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IXO630_000365	COG1546	Belongs to the CinA family
IXO630_000380	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IXO630_000385	COG2137	regulation of response to DNA damage stimulus
IXO630_000390	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IXO630_000395	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IXO630_000420	COG0305	Participates in initiation and elongation during chromosome replication
IXO630_000425	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IXO630_000445	COG1741	Belongs to the pirin family
IXO630_000450	COG0583	DNA-binding transcription factor activity
IXO630_000480	COG0351	phosphomethylpyrimidine kinase
IXO630_000490	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
IXO630_000495	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IXO630_000510	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IXO630_000520	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IXO630_000525	COG3734	2-keto-3-deoxy-galactonokinase
IXO630_000535	COG4948	Mandelate Racemase Muconate Lactonizing
IXO630_000540	COG0800	Aldolase
IXO630_000555	COG1501	Belongs to the glycosyl hydrolase 31 family
IXO630_000565	COG1070	Carbohydrate kinase
IXO630_000575	COG0477	Major facilitator Superfamily
IXO630_000595	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IXO630_000645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IXO630_000650	COG2258	MOSC domain
IXO630_000660	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IXO630_000665	COG0505	Belongs to the CarA family
IXO630_000675	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IXO630_000680	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IXO630_000690	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IXO630_000745	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IXO630_000755	COG2198	Histidine kinase
IXO630_000755	COG0784	Response regulator, receiver
IXO630_000755	COG2205	protein histidine kinase activity
IXO630_000760	COG1024	Enoyl-CoA hydratase
IXO630_000765	COG0318	PFAM AMP-dependent synthetase and ligase
IXO630_000795	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IXO630_000850	COG3039	Transposase
IXO630_000870	COG0835	chemotaxis
IXO630_000885	COG0840	transmembrane signaling receptor activity
IXO630_000890	COG0840	transmembrane signaling receptor activity
IXO630_000895	COG0840	transmembrane signaling receptor activity
IXO630_000900	COG0840	transmembrane signaling receptor activity
IXO630_000910	COG0840	transmembrane signaling receptor activity
IXO630_000920	COG0840	transmembrane signaling receptor activity
IXO630_000930	COG0840	transmembrane signaling receptor activity
IXO630_000950	COG0745	RESPONSE REGULATOR receiver
IXO630_000960	COG0835	chemotaxis
IXO630_000970	COG1360	Flagellar Motor Protein
IXO630_000975	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IXO630_000995	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IXO630_001005	COG4771	TonB-dependent receptor
IXO630_001120	COG3039	Transposase
IXO630_001145	COG3039	Transposase
IXO630_001160	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IXO630_001160	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IXO630_001165	COG1105	Belongs to the carbohydrate kinase PfkB family
IXO630_001170	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IXO630_001170	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IXO630_001175	COG1609	Transcriptional regulator
IXO630_001200	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IXO630_001205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IXO630_001215	COG2902	Dehydrogenase
IXO630_001220	COG3039	Transposase
IXO630_001230	COG0784	Response regulator, receiver
IXO630_001230	COG5002	protein histidine kinase activity
IXO630_001230	COG2205	protein histidine kinase activity
IXO630_001235	COG2733	membrane
IXO630_001245	COG1121	(ABC) transporter
IXO630_001250	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IXO630_001255	COG2223	nitrite transmembrane transporter activity
IXO630_001265	COG0243	molybdopterin cofactor binding
IXO630_001275	COG0477	Major facilitator Superfamily
IXO630_001285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IXO630_001290	COG0174	glutamine synthetase
IXO630_001370	COG3039	Transposase
IXO630_001380	COG0583	DNA-binding transcription factor activity
IXO630_001455	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
IXO630_001460	COG0235	Class ii aldolase
IXO630_001465	COG0531	amino acid
IXO630_001470	COG0531	amino acid
IXO630_001480	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IXO630_001485	COG0277	FAD linked oxidase domain protein
IXO630_001550	COG0436	Aminotransferase
IXO630_001575	COG1187	pseudouridine synthase activity
IXO630_001580	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IXO630_001585	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IXO630_001590	COG2350	Protein conserved in bacteria
IXO630_001620	COG1175	transmembrane transport
IXO630_001625	COG0395	ABC-type sugar transport system, permease component
IXO630_001650	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IXO630_001660	COG2957	Belongs to the agmatine deiminase family
IXO630_001675	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IXO630_001680	COG0539	negative regulation of cytoplasmic translation
IXO630_001685	COG0776	regulation of translation
IXO630_001695	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
IXO630_001700	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IXO630_001710	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IXO630_001730	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IXO630_001745	COG0582	viral genome integration into host DNA
IXO630_001840	COG3002	Belongs to the UPF0753 family
IXO630_001845	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IXO630_001850	COG0583	DNA-binding transcription factor activity
IXO630_001880	COG0583	DNA-binding transcription factor activity
IXO630_001885	COG0583	DNA-binding transcription factor activity
IXO630_001900	COG1914	H( )-stimulated, divalent metal cation uptake system
IXO630_001920	COG0668	transmembrane transport
IXO630_001930	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
IXO630_001945	COG1028	Short-chain dehydrogenase reductase Sdr
IXO630_001950	COG1183	phosphatidylcholine synthase activity
IXO630_001960	COG3243	poly(R)-hydroxyalkanoic acid synthase
IXO630_001975	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IXO630_001975	COG0723	plastoquinol--plastocyanin reductase activity
IXO630_001985	COG2183	response to ionizing radiation
IXO630_002000	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
IXO630_002015	COG0671	phosphoesterase, PA-phosphatase related
IXO630_002035	COG1794	racemase activity, acting on amino acids and derivatives
IXO630_002040	COG0697	spore germination
IXO630_002045	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IXO630_002050	COG0167	dihydroorotate dehydrogenase activity
IXO630_002065	COG1012	belongs to the aldehyde dehydrogenase family
IXO630_002100	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IXO630_002115	COG0124	histidyl-tRNA synthetase
IXO630_002135	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IXO630_002150	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IXO630_002150	COG0131	Imidazoleglycerol-phosphate dehydratase
IXO630_002160	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IXO630_002170	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IXO630_002170	COG0140	phosphoribosyl-ATP diphosphatase activity
IXO630_002210	COG0653	protein targeting
IXO630_002235	COG3039	Transposase
IXO630_002295	COG2201	protein-glutamate methylesterase activity
IXO630_002305	COG2801	Transposase and inactivated derivatives
IXO630_002320	COG3039	Transposase
IXO630_002340	COG3328	transposase activity
IXO630_002375	COG0322	excinuclease ABC activity
IXO630_002385	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IXO630_002395	COG1663	tetraacyldisaccharide 4'-kinase activity
IXO630_002410	COG0811	peptide transport
IXO630_002435	COG4591	ABC-type transport system involved in lipoprotein release permease component
IXO630_002450	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IXO630_002465	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IXO630_002480	COG0354	folic acid binding
IXO630_002495	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IXO630_002505	COG0363	glucosamine-6-phosphate deaminase activity
IXO630_002510	COG0129	dihydroxy-acid dehydratase activity
IXO630_002515	COG0800	Aldolase
IXO630_002555	COG2205	protein histidine kinase activity
IXO630_002555	COG5002	protein histidine kinase activity
IXO630_002555	COG0784	Response regulator, receiver
IXO630_002570	COG3039	Transposase
IXO630_002640	COG0386	Belongs to the glutathione peroxidase family
IXO630_002725	COG2203	Gaf domain
IXO630_002725	COG3706	GGDEF domain
IXO630_002725	COG4251	negative regulation of phosphorylation
IXO630_002725	COG5001	Diguanylate cyclase
IXO630_002740	COG1472	Belongs to the glycosyl hydrolase 3 family
IXO630_002770	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IXO630_002775	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IXO630_002785	COG0617	tRNA 3'-terminal CCA addition
IXO630_002795	COG1469	GTP cyclohydrolase I activity
IXO630_002800	COG0860	N-Acetylmuramoyl-L-alanine amidase
IXO630_002845	COG4566	intracellular signal transduction
IXO630_002855	COG3039	Transposase
IXO630_002880	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IXO630_002885	COG0077	Prephenate dehydratase
IXO630_002885	COG1605	Chorismate mutase
IXO630_002895	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IXO630_002935	COG1228	amidohydrolase
IXO630_002940	COG2986	histidine ammonia-lyase
IXO630_002950	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IXO630_002975	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IXO630_002990	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
IXO630_003010	COG3115	cell septum assembly
IXO630_003020	COG0359	binds to the 23S rRNA
IXO630_003030	COG0360	Binds together with S18 to 16S ribosomal RNA
IXO630_003035	COG0316	Belongs to the HesB IscA family
IXO630_003065	COG0288	reversible hydration of carbon dioxide
IXO630_003100	COG2925	Exonuclease
IXO630_003110	COG0667	Aldo Keto reductase
IXO630_003135	COG0116	Belongs to the methyltransferase superfamily
IXO630_003135	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IXO630_003180	COG0494	nUDIX hydrolase
IXO630_003190	COG1024	Enoyl-CoA hydratase
IXO630_003200	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IXO630_003220	COG3039	Transposase
IXO630_003260	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IXO630_003265	COG0573	inorganic phosphate transmembrane transporter activity
IXO630_003280	COG0704	Plays a role in the regulation of phosphate uptake
IXO630_003290	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IXO630_003325	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IXO630_003330	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IXO630_003335	COG1862	Preprotein translocase
IXO630_003340	COG0343	queuine tRNA-ribosyltransferase activity
IXO630_003390	COG3039	Transposase
IXO630_003425	COG3039	Transposase
IXO630_003450	COG0405	Gamma-glutamyltransferase
IXO630_003455	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IXO630_003465	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IXO630_003470	COG0742	ribosomal rna small subunit methyltransferase
IXO630_003510	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IXO630_003565	COG0303	'Molybdopterin
IXO630_003575	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IXO630_003585	COG1426	Protein conserved in bacteria
IXO630_003595	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IXO630_003610	COG1024	Enoyl-CoA hydratase
IXO630_003610	COG1250	3-hydroxyacyl-CoA dehydrogenase
IXO630_003615	COG0183	Belongs to the thiolase family
IXO630_003620	COG0038	chloride channel
IXO630_003640	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IXO630_003660	COG1674	ftsk spoiiie
IXO630_003665	COG0492	ferredoxin-NADP+ reductase activity
IXO630_003690	COG0542	response to heat
IXO630_003705	COG0482	sulfurtransferase activity
IXO630_003730	COG5001	Diguanylate cyclase
IXO630_003735	COG4585	Histidine kinase
IXO630_003745	COG5002	protein histidine kinase activity
IXO630_003765	COG0784	Response regulator, receiver
IXO630_003765	COG0835	chemotaxis
IXO630_003775	COG1558	bacterial-type flagellum-dependent cell motility
IXO630_003780	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
IXO630_003790	COG4787	bacterial-type flagellum-dependent cell motility
IXO630_003825	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IXO630_003830	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IXO630_003860	COG2201	protein-glutamate methylesterase activity
IXO630_003880	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IXO630_003890	COG1028	Short-chain dehydrogenase reductase Sdr
IXO630_003920	COG1677	Flagellar hook-basal body complex protein FliE
IXO630_003970	COG3190	flagellar
IXO630_003985	COG1684	flagellar biosynthetic protein fliR
IXO630_004040	COG0643	Histidine kinase
IXO630_004040	COG2198	Histidine kinase
IXO630_004040	COG0784	Response regulator, receiver
IXO630_004065	COG3039	Transposase
IXO630_004115	COG3039	Transposase
IXO630_004200	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IXO630_004205	COG4988	ABC transporter
IXO630_004215	COG1271	oxidase subunit
IXO630_004245	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IXO630_004265	COG0165	Argininosuccinate lyase
IXO630_004280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IXO630_004285	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IXO630_004295	COG0137	argininosuccinate synthase activity
IXO630_004300	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IXO630_004315	COG2166	iron-sulfur cluster assembly
IXO630_004340	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IXO630_004385	COG4677	pectinesterase activity
IXO630_004410	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IXO630_004415	COG0402	S-adenosylhomocysteine deaminase activity
IXO630_004430	COG1509	lysine 2,3-aminomutase activity
IXO630_004435	COG3300	MHYT domain
IXO630_004435	COG5001	Diguanylate cyclase
IXO630_004450	COG0483	inositol monophosphate 1-phosphatase activity
IXO630_004455	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IXO630_004475	COG0488	(ABC) transporter
IXO630_004480	COG0513	Belongs to the DEAD box helicase family
IXO630_004485	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IXO630_004490	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
IXO630_004500	COG0625	glutathione transferase activity
IXO630_004510	COG1671	Belongs to the UPF0178 family
IXO630_004515	COG4681	YaeQ
IXO630_004520	COG2081	HI0933 family
IXO630_004530	COG0501	Belongs to the peptidase M48B family
IXO630_004540	COG1028	Short-chain dehydrogenase reductase Sdr
IXO630_004560	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IXO630_004565	COG0860	N-Acetylmuramoyl-L-alanine amidase
IXO630_004570	COG0802	atpase or kinase
IXO630_004575	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IXO630_004575	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IXO630_004580	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IXO630_004600	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IXO630_004685	COG3328	transposase activity
IXO630_004720	COG2969	positive regulation of protein catabolic process
IXO630_004725	COG0625	glutathione transferase activity
IXO630_004730	COG2857	Cytochrome c1
IXO630_004735	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IXO630_004740	COG0723	plastoquinol--plastocyanin reductase activity
IXO630_004745	COG0741	lytic transglycosylase activity
IXO630_004770	COG1702	phosphate starvation-inducible protein PhoH
IXO630_004790	COG4535	Mg2 and Co2 transporter CorC
IXO630_004805	COG1012	belongs to the aldehyde dehydrogenase family
IXO630_004815	COG1177	transmembrane transport
IXO630_004825	COG3842	ATPase activity
IXO630_004895	COG3039	Transposase
IXO630_004905	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IXO630_004925	COG0557	exoribonuclease II activity
IXO630_004950	COG1960	acyl-CoA dehydrogenase activity
IXO630_004955	COG2226	methyltransferase
IXO630_004960	COG1410	methionine synthase
IXO630_004960	COG0646	methionine synthase
IXO630_004965	COG0646	methionine synthase
IXO630_004965	COG1410	methionine synthase
IXO630_004975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IXO630_004985	COG1609	Transcriptional regulator
IXO630_005000	COG2900	Belongs to the SlyX family
IXO630_005015	COG0386	Belongs to the glutathione peroxidase family
IXO630_005025	COG1725	Transcriptional regulator
IXO630_005030	COG1131	(ABC) transporter
IXO630_005110	COG2850	peptidyl-arginine hydroxylation
IXO630_005145	COG1132	(ABC) transporter
IXO630_005160	COG0583	DNA-binding transcription factor activity
IXO630_005175	COG1605	Chorismate mutase
IXO630_005175	COG0287	Prephenate dehydrogenase
IXO630_005180	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
IXO630_005185	COG0484	heat shock protein binding
IXO630_005195	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IXO630_005205	COG0497	DNA recombination
IXO630_005215	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IXO630_005220	COG2914	Belongs to the UPF0125 (RnfH) family
IXO630_005230	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IXO630_005245	COG1960	acyl-CoA dehydrogenase activity
IXO630_005255	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IXO630_005310	COG2814	Major facilitator Superfamily
IXO630_005315	COG1566	PFAM secretion protein HlyD family protein
IXO630_005365	COG4774	siderophore transport
IXO630_005375	COG0367	asparagine synthase
IXO630_005380	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IXO630_005390	COG1393	Belongs to the ArsC family
IXO630_005450	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IXO630_005465	COG0233	cytoplasmic translational termination
IXO630_005475	COG0575	Belongs to the CDS family
IXO630_005485	COG0750	zinc metalloprotease
IXO630_005500	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IXO630_005505	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IXO630_005525	COG0825	malonyl-CoA metabolic process
IXO630_005535	COG4771	TonB-dependent receptor
IXO630_005560	COG1981	membrane
IXO630_005605	COG2895	sulfate adenylyltransferase (ATP) activity
IXO630_005605	COG0529	Catalyzes the synthesis of activated sulfate
IXO630_005645	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IXO630_005660	COG2040	homocysteine
IXO630_005665	COG0833	amino acid
IXO630_005685	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IXO630_005685	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IXO630_005695	COG2878	Part of a membrane complex involved in electron transport
IXO630_005710	COG1595	DNA-templated transcription, initiation
IXO630_005735	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IXO630_005750	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IXO630_005755	COG0251	oxidation-reduction process
IXO630_005765	COG0392	lysyltransferase activity
IXO630_005765	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IXO630_005795	COG3039	Transposase
IXO630_005820	COG2814	Major facilitator Superfamily
IXO630_005825	COG1902	pentaerythritol trinitrate reductase activity
IXO630_005835	COG2824	Alkylphosphonate utilization operon protein PhnA
IXO630_005850	COG1047	Peptidyl-prolyl cis-trans
IXO630_005885	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IXO630_005900	COG1451	nucleotide metabolic process
IXO630_005905	COG3039	Transposase
IXO630_005925	COG0183	Belongs to the thiolase family
IXO630_005955	COG1793	dna ligase
IXO630_005955	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
IXO630_005965	COG1793	dna ligase
IXO630_005970	COG1201	RNA secondary structure unwinding
IXO630_005990	COG1278	Cold shock
IXO630_005995	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IXO630_006000	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
IXO630_006010	COG3046	protein related to deoxyribodipyrimidine photolyase
IXO630_006015	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
IXO630_006020	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IXO630_006025	COG3039	Transposase
IXO630_006035	COG2954	triphosphatase activity
IXO630_006050	COG1381	Involved in DNA repair and RecF pathway recombination
IXO630_006075	COG0481	GTPase activity
IXO630_006080	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IXO630_006095	COG1250	3-hydroxyacyl-CoA dehydrogenase
IXO630_006095	COG1024	Enoyl-CoA hydratase
IXO630_006120	COG1024	Enoyl-CoA hydratase
IXO630_006125	COG1960	acyl-CoA dehydrogenase activity
IXO630_006150	COG3250	beta-galactosidase activity
IXO630_006195	COG2353	YceI-like domain
IXO630_006205	COG2353	YceI-like domain
IXO630_006220	COG1760	l-serine dehydratase
IXO630_006230	COG0626	cystathionine gamma-synthase activity
IXO630_006235	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IXO630_006240	COG0739	heme binding
IXO630_006250	COG1272	protein, Hemolysin III
IXO630_006270	COG0463	Glycosyl transferase, family 2
IXO630_006280	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IXO630_006290	COG4771	TonB-dependent receptor
IXO630_006295	COG1309	transcriptional regulator
IXO630_006305	COG1960	acyl-CoA dehydrogenase activity
IXO630_006325	COG3039	Transposase
IXO630_006340	COG0509	glycine decarboxylation via glycine cleavage system
IXO630_006355	COG0330	HflC and HflK could
IXO630_006370	COG3956	TIGRFAM MazG family protein
IXO630_006380	COG0494	nUDIX hydrolase
IXO630_006390	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IXO630_006395	COG0837	glucose binding
IXO630_006410	COG3858	chitin binding
IXO630_006410	COG1388	LysM domain
IXO630_006420	COG3525	Glycosyl hydrolase, family 20, catalytic domain
IXO630_006430	COG1472	Belongs to the glycosyl hydrolase 3 family
IXO630_006470	COG3537	Alpha-1,2-mannosidase
IXO630_006515	COG1446	asparaginase
IXO630_006540	COG3039	Transposase
IXO630_006560	COG0784	Response regulator, receiver
IXO630_006560	COG0643	Histidine kinase
IXO630_006560	COG2198	Histidine kinase
IXO630_006565	COG0840	transmembrane signaling receptor activity
IXO630_006570	COG0835	chemotaxis
IXO630_006585	COG0189	ligase activity
IXO630_006595	COG1397	ADP-ribosylglycohydrolase
IXO630_006605	COG1199	ATP-dependent helicase activity
IXO630_006615	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IXO630_006620	COG1215	transferase activity, transferring glycosyl groups
IXO630_006630	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IXO630_006650	COG0535	radical SAM domain protein
IXO630_006655	COG0535	radical SAM domain protein
IXO630_006685	COG1643	Atp-dependent helicase
IXO630_006690	COG0783	Belongs to the Dps family
IXO630_006695	COG0514	ATP-dependent DNA helicase (RecQ)
IXO630_006765	COG4695	Portal protein
IXO630_006810	COG3179	chitinase
IXO630_006990	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IXO630_007050	COG1187	pseudouridine synthase activity
IXO630_007055	COG0602	queuosine metabolic process
IXO630_007065	COG2885	chlorophyll binding
IXO630_007080	COG0848	biopolymer transport protein
IXO630_007090	COG0824	Thioesterase
IXO630_007095	COG2255	four-way junction helicase activity
IXO630_007105	COG0632	four-way junction helicase activity
IXO630_007215	COG3328	transposase activity
IXO630_007250	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IXO630_007255	COG1845	cytochrome c oxidase, subunit III
IXO630_007260	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IXO630_007275	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IXO630_007280	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IXO630_007290	COG0196	riboflavin kinase activity
IXO630_007295	COG0728	peptidoglycan biosynthetic process
IXO630_007300	COG0268	Binds directly to 16S ribosomal RNA
IXO630_007305	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IXO630_007310	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IXO630_007320	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IXO630_007325	COG0824	Thioesterase
IXO630_007340	COG1946	Acyl-CoA thioesterase
IXO630_007350	COG1595	DNA-templated transcription, initiation
IXO630_007365	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
IXO630_007400	COG1877	trehalose-phosphatase activity
IXO630_007405	COG3387	PFAM Glycoside hydrolase 15-related
IXO630_007430	COG0564	pseudouridine synthase activity
IXO630_007435	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IXO630_007440	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IXO630_007440	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IXO630_007450	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IXO630_007455	COG0045	succinate-CoA ligase (ADP-forming) activity
IXO630_007495	COG2194	sulfuric ester hydrolase activity
IXO630_007500	COG4969	Belongs to the N-Me-Phe pilin family
IXO630_007510	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
IXO630_007540	COG3039	Transposase
IXO630_007570	COG1132	(ABC) transporter
IXO630_007600	COG0745	RESPONSE REGULATOR receiver
IXO630_007605	COG5000	phosphorelay sensor kinase activity
IXO630_007605	COG5002	protein histidine kinase activity
IXO630_007610	COG0475	glutathione-regulated potassium exporter activity
IXO630_007620	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IXO630_007640	COG1187	pseudouridine synthase activity
IXO630_007645	COG5001	Diguanylate cyclase
IXO630_007645	COG5002	protein histidine kinase activity
IXO630_007745	COG1028	Short-chain dehydrogenase reductase Sdr
IXO630_007760	COG0415	Belongs to the DNA photolyase family
IXO630_007765	COG0305	Participates in initiation and elongation during chromosome replication
IXO630_007775	COG0367	asparagine synthase
IXO630_007790	COG1960	acyl-CoA dehydrogenase activity
IXO630_007805	COG0084	hydrolase, TatD family'
IXO630_007810	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IXO630_007870	COG0735	belongs to the Fur family
IXO630_007875	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IXO630_007900	COG3039	Transposase
IXO630_007950	COG2205	protein histidine kinase activity
IXO630_007960	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IXO630_007970	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IXO630_007985	COG2198	Histidine kinase
IXO630_007985	COG0643	Histidine kinase
IXO630_007990	COG0840	transmembrane signaling receptor activity
IXO630_007995	COG0835	chemotaxis
IXO630_008000	COG2199	diguanylate cyclase activity
IXO630_008000	COG2200	EAL domain
IXO630_008000	COG2202	Pas domain
IXO630_008005	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IXO630_008020	COG3590	peptidase
IXO630_008035	COG0588	phosphoglycerate mutase activity
IXO630_008040	COG1515	deoxyribonuclease V activity
IXO630_008050	COG1741	Belongs to the pirin family
IXO630_008135	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IXO630_008145	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IXO630_008240	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IXO630_008255	COG2197	response regulator
IXO630_008260	COG4585	Histidine kinase
IXO630_008275	COG2894	cell division
IXO630_008280	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
IXO630_008290	COG0642	Histidine kinase
IXO630_008295	COG0745	RESPONSE REGULATOR receiver
IXO630_008300	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IXO630_008310	COG2194	sulfuric ester hydrolase activity
IXO630_008340	COG3551	Protein conserved in bacteria
IXO630_008400	COG0203	ribosomal protein L17
IXO630_008410	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IXO630_008415	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IXO630_008425	COG0201	protein transport
IXO630_008435	COG1841	ribosomal large subunit assembly
IXO630_008445	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IXO630_008465	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IXO630_008475	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IXO630_008480	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IXO630_008485	COG0255	Belongs to the universal ribosomal protein uL29 family
IXO630_008490	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IXO630_008500	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IXO630_008515	COG0089	rRNA binding
IXO630_008520	COG0088	Forms part of the polypeptide exit tunnel
IXO630_008525	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IXO630_008530	COG0051	transcription antitermination factor activity, RNA binding
IXO630_008550	COG0049	tRNA binding
IXO630_008555	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IXO630_008560	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IXO630_008565	COG0085	RNA polymerase activity
IXO630_008570	COG0222	ribosome binding
IXO630_008575	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IXO630_008585	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IXO630_008590	COG0250	Participates in transcription elongation, termination and antitermination
IXO630_008595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IXO630_008625	COG0012	GTP binding
IXO630_008630	COG0193	aminoacyl-tRNA hydrolase activity
IXO630_008640	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IXO630_008655	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
IXO630_008665	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IXO630_008670	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IXO630_008685	COG0521	Mo-molybdopterin cofactor biosynthetic process
IXO630_008705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IXO630_008710	COG1295	ribonuclease BN
IXO630_008740	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IXO630_008745	COG1404	Belongs to the peptidase S8 family
IXO630_008750	COG1404	Belongs to the peptidase S8 family
IXO630_008760	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IXO630_008785	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
IXO630_008810	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
IXO630_008825	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IXO630_008825	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IXO630_008870	COG2890	protein-(glutamine-N5) methyltransferase activity
IXO630_008880	COG3634	alkyl hydroperoxide reductase activity
IXO630_008885	COG0583	DNA-binding transcription factor activity
IXO630_008895	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IXO630_008920	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IXO630_008955	COG0584	glycerophosphoryl diester phosphodiesterase
IXO630_008975	COG3039	Transposase
IXO630_008990	COG0625	glutathione transferase activity
IXO630_008995	COG0039	L-malate dehydrogenase activity
IXO630_009000	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IXO630_009005	COG1217	gtp-binding protein TYPA
IXO630_009025	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
IXO630_009130	COG3293	Transposase
IXO630_009160	COG3781	membrane
IXO630_009170	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IXO630_009200	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
IXO630_009220	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IXO630_009245	COG3710	Transcriptional regulator
IXO630_009250	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IXO630_009260	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IXO630_009290	COG2226	methyltransferase
IXO630_009295	COG0066	3-isopropylmalate dehydratase activity
IXO630_009300	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IXO630_009330	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IXO630_009335	COG1538	Outer membrane efflux protein
IXO630_009340	COG1519	Transferase
IXO630_009345	COG1560	Kdo2-lipid A biosynthetic process
IXO630_009400	COG0308	aminopeptidase N
IXO630_009405	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IXO630_009415	COG0330	HflC and HflK could
IXO630_009420	COG0330	HflC and HflK could
IXO630_009440	COG0678	peroxiredoxin activity
IXO630_009450	COG2826	transposase and inactivated derivatives, IS30 family
IXO630_009480	COG3039	Transposase
IXO630_009510	COG3829	transcription factor binding
IXO630_009545	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IXO630_009550	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IXO630_009560	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IXO630_009565	COG1028	Short-chain dehydrogenase reductase Sdr
IXO630_009590	COG1399	metal-binding, possibly nucleic acid-binding protein
IXO630_009605	COG3039	Transposase
IXO630_009645	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IXO630_009695	COG2188	Transcriptional regulator
IXO630_009710	COG1450	Type ii and iii secretion system protein
IXO630_009725	COG3166	PFAM Fimbrial assembly family protein
IXO630_009730	COG3156	type II secretion system protein K
IXO630_009735	COG4795	General secretion pathway protein
IXO630_009740	COG2165	general secretion pathway protein
IXO630_009745	COG4970	Tfp pilus assembly protein FimT
IXO630_009750	COG2165	general secretion pathway protein
IXO630_009755	COG1459	type II secretion system
IXO630_009765	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IXO630_009775	COG1404	Belongs to the peptidase S8 family
IXO630_009785	COG5295	Hep Hag repeat protein
IXO630_009790	COG0047	phosphoribosylformylglycinamidine synthase activity
IXO630_009790	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IXO630_009795	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IXO630_009800	COG4974	Belongs to the 'phage' integrase family
IXO630_009810	COG0795	lipopolysaccharide-transporting ATPase activity
IXO630_009820	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IXO630_009835	COG0525	valine-tRNA ligase activity
IXO630_009870	COG3039	Transposase
IXO630_009905	COG3039	Transposase
IXO630_009935	COG1183	phosphatidylcholine synthase activity
IXO630_009945	COG0442	prolyl-tRNA aminoacylation
IXO630_009960	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IXO630_009965	COG1127	ABC transporter
IXO630_009970	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IXO630_009970	COG3218	ABC-type transport auxiliary lipoprotein component
IXO630_010005	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IXO630_010010	COG0662	Cupin 2, conserved barrel domain protein
IXO630_010010	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
IXO630_010035	COG2086	electron transfer activity
IXO630_010100	COG0626	cystathionine gamma-synthase activity
IXO630_010130	COG0625	glutathione transferase activity
IXO630_010140	COG0513	Belongs to the DEAD box helicase family
IXO630_010145	COG0720	synthase
IXO630_010155	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IXO630_010160	COG1956	GAF domain-containing protein
IXO630_010195	COG0339	signal peptide processing
IXO630_010245	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IXO630_010250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IXO630_010300	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IXO630_010305	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IXO630_010310	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IXO630_010315	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IXO630_010325	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IXO630_010335	COG0356	it plays a direct role in the translocation of protons across the membrane
IXO630_010355	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IXO630_010365	COG0508	dehydrogenase complex catalyzes the overall conversion of
IXO630_010395	COG2011	ABC-type metal ion transport system permease component
IXO630_010405	COG0697	spore germination
IXO630_010440	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IXO630_010445	COG1187	pseudouridine synthase activity
IXO630_010450	COG2813	Specifically methylates the guanine in position
IXO630_010480	COG2202	Pas domain
IXO630_010480	COG2205	protein histidine kinase activity
IXO630_010505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IXO630_010555	COG0745	RESPONSE REGULATOR receiver
IXO630_010570	COG1404	Belongs to the peptidase S8 family
IXO630_010585	COG0842	Transport permease protein
IXO630_010590	COG1131	(ABC) transporter
IXO630_010595	COG0025	NhaP-type Na H and K H
IXO630_010610	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
IXO630_010620	COG1573	uracil-dna glycosylase
IXO630_010630	COG3384	dioxygenase
IXO630_010645	COG0667	Aldo Keto reductase
IXO630_010655	COG3590	peptidase
IXO630_010675	COG0531	amino acid
IXO630_010700	COG2972	Histidine kinase
IXO630_010750	COG1271	oxidase subunit
IXO630_010905	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IXO630_010915	COG1560	Kdo2-lipid A biosynthetic process
IXO630_010965	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IXO630_010965	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IXO630_010970	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IXO630_010975	COG0242	peptide deformylase activity
IXO630_010980	COG1652	LysM domain
IXO630_010985	COG0758	DNA mediated transformation
IXO630_010990	COG2922	Belongs to the Smg family
IXO630_011005	COG1754	DNA topoisomerase type I activity
IXO630_011005	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IXO630_011010	COG0009	L-threonylcarbamoyladenylate synthase
IXO630_011025	COG1028	Short-chain dehydrogenase reductase Sdr
IXO630_011035	COG0616	signal peptide processing
IXO630_011040	COG0534	Mate efflux family protein
IXO630_011065	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IXO630_011100	COG1324	tolerance protein
IXO630_011110	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
IXO630_011115	COG0511	ligase activity, forming carbon-carbon bonds
IXO630_011125	COG0439	Biotin carboxylase
IXO630_011170	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
IXO630_011230	COG3039	Transposase
IXO630_011255	COG3039	Transposase
IXO630_011325	COG3210	domain, Protein
IXO630_011330	COG2831	hemolysin activation secretion protein
IXO630_011360	COG2267	carboxylic ester hydrolase activity
IXO630_011365	COG2267	carboxylic ester hydrolase activity
IXO630_011375	COG0138	bifunctional purine biosynthesis protein purh
IXO630_011385	COG0151	Belongs to the GarS family
IXO630_011410	COG1289	transmembrane transporter activity
IXO630_011425	COG2814	Major facilitator Superfamily
IXO630_011440	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
IXO630_011475	COG0745	RESPONSE REGULATOR receiver
IXO630_011520	COG0739	heme binding
IXO630_011535	COG2211	Major facilitator Superfamily
IXO630_011540	COG0708	Exodeoxyribonuclease III
IXO630_011555	COG1192	Involved in chromosome partitioning
IXO630_011560	COG1475	DNA binding
IXO630_011575	COG0463	Glycosyl transferase, family 2
IXO630_011600	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IXO630_011610	COG0018	arginyl-trna synthetase
IXO630_011625	COG4221	oxidoreductase activity
IXO630_011650	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IXO630_011655	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IXO630_011670	COG3485	protocatechuate 3,4-dioxygenase
IXO630_011675	COG3485	protocatechuate 3,4-dioxygenase
IXO630_011710	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IXO630_011715	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IXO630_011725	COG0045	succinate-CoA ligase (ADP-forming) activity
IXO630_011725	COG1042	CoA-binding domain protein
IXO630_011725	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IXO630_011740	COG2239	Acts as a magnesium transporter
IXO630_011755	COG3039	Transposase
IXO630_011765	COG3328	transposase activity
IXO630_011770	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IXO630_011770	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IXO630_011780	COG1473	amidohydrolase
IXO630_011785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IXO630_011790	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IXO630_011800	COG5383	Protein conserved in bacteria
IXO630_011825	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IXO630_011830	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
IXO630_011845	COG0028	Belongs to the TPP enzyme family
IXO630_011850	COG4191	Histidine kinase
IXO630_011875	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IXO630_011890	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IXO630_011895	COG3177	Filamentation induced by cAMP protein fic
IXO630_011910	COG0596	Alpha beta hydrolase
IXO630_011915	COG0727	PFAM Uncharacterised protein family (UPF0153)
IXO630_011920	COG0318	PFAM AMP-dependent synthetase and ligase
IXO630_011925	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IXO630_011975	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IXO630_011985	COG0129	dihydroxy-acid dehydratase activity
IXO630_012005	COG3039	Transposase
IXO630_012015	COG0408	coproporphyrinogen oxidase activity
IXO630_012055	COG0232	Belongs to the dGTPase family. Type 2 subfamily
IXO630_012075	COG2201	protein-glutamate methylesterase activity
IXO630_012115	COG2353	YceI-like domain
IXO630_012145	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IXO630_012160	COG3386	PFAM SMP-30 Gluconolaconase
IXO630_012205	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IXO630_012225	COG0459	protein refolding
IXO630_012250	COG1252	NADH dehydrogenase
IXO630_012260	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IXO630_012265	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IXO630_012270	COG2201	protein-glutamate methylesterase activity
IXO630_012275	COG2177	Part of the ABC transporter FtsEX involved in
IXO630_012280	COG2884	Cell division ATP-binding protein ftsE
IXO630_012290	COG3118	belongs to the thioredoxin family
IXO630_012295	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IXO630_012310	COG0729	surface antigen
IXO630_012315	COG2911	Protein conserved in bacteria
IXO630_012350	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IXO630_012365	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IXO630_012415	COG1733	regulation of RNA biosynthetic process
IXO630_012420	COG0702	epimerase
IXO630_012450	COG0583	DNA-binding transcription factor activity
IXO630_012455	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IXO630_012475	COG0745	RESPONSE REGULATOR receiver
IXO630_012505	COG1902	pentaerythritol trinitrate reductase activity
IXO630_012510	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IXO630_012520	COG2814	Major facilitator Superfamily
IXO630_012525	COG0583	DNA-binding transcription factor activity
IXO630_012540	COG0084	hydrolase, TatD family'
IXO630_012585	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IXO630_012605	COG2072	flavoprotein involved in K transport
IXO630_012665	COG4770	biotin carboxylase activity
IXO630_012670	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IXO630_012675	COG1960	acyl-CoA dehydrogenase activity
IXO630_012730	COG0523	cobalamin synthesis protein
IXO630_012740	COG0697	spore germination
IXO630_012750	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IXO630_012765	COG4771	TonB-dependent receptor
IXO630_012770	COG0457	Tetratricopeptide repeat
IXO630_012780	COG0752	glycyl-tRNA synthetase alpha subunit
IXO630_012785	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IXO630_012800	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IXO630_012800	COG0519	Catalyzes the synthesis of GMP from XMP
IXO630_012810	COG0805	protein transport
IXO630_012820	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IXO630_012830	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
IXO630_012855	COG2974	May be involved in recombination
IXO630_012860	COG0037	tRNA processing
IXO630_012875	COG3661	Belongs to the glycosyl hydrolase 67 family
IXO630_012885	COG4948	Mandelate Racemase Muconate Lactonizing
IXO630_012895	COG1472	Belongs to the glycosyl hydrolase 3 family
IXO630_012900	COG0246	Mannitol dehydrogenase
IXO630_012925	COG3693	PFAM glycoside hydrolase, family 10
IXO630_012945	COG2211	Major facilitator Superfamily
IXO630_012990	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IXO630_013030	COG1846	Transcriptional regulator
IXO630_013035	COG1764	response to oxidative stress
IXO630_013110	COG3549	Plasmid maintenance system killer
IXO630_013120	COG1074	ATP-dependent DNA helicase activity
IXO630_013125	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IXO630_013170	COG2032	superoxide dismutase activity
IXO630_013175	COG2032	superoxide dismutase activity
IXO630_013180	COG2204	response regulator
IXO630_013185	COG3852	Histidine kinase
IXO630_013190	COG0004	ammonium transporteR
IXO630_013195	COG0347	Belongs to the P(II) protein family
IXO630_013200	COG0174	glutamine synthetase
IXO630_013205	COG1968	undecaprenyl-diphosphatase activity
IXO630_013250	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IXO630_013260	COG2062	phosphohistidine phosphatase, SixA
IXO630_013265	COG0489	protein tyrosine kinase activity
IXO630_013285	COG1396	sequence-specific DNA binding
IXO630_013290	COG3550	peptidyl-serine autophosphorylation
IXO630_013295	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
IXO630_013300	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IXO630_013315	COG1125	glycine betaine transport
IXO630_013315	COG0517	IMP dehydrogenase activity
IXO630_013330	COG1119	ATPase activity
IXO630_013340	COG1752	Esterase of the alpha-beta hydrolase superfamily
IXO630_013355	COG3039	Transposase
IXO630_013380	COG0656	L-ascorbic acid biosynthetic process
IXO630_013385	COG2130	NADP-dependent
IXO630_013390	COG0667	Aldo Keto reductase
IXO630_013400	COG1187	pseudouridine synthase activity
IXO630_013410	COG1643	Atp-dependent helicase
IXO630_013415	COG4807	Protein conserved in bacteria
IXO630_013420	COG4948	Mandelate Racemase Muconate Lactonizing
IXO630_013425	COG0179	Fumarylacetoacetate (FAA) hydrolase
IXO630_013430	COG1028	Short-chain dehydrogenase reductase Sdr
IXO630_013450	COG3507	Belongs to the glycosyl hydrolase 43 family
IXO630_013490	COG3162	membrane
IXO630_013495	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IXO630_013515	COG0708	Exodeoxyribonuclease III
IXO630_013530	COG2091	lysine biosynthetic process via aminoadipic acid
IXO630_013540	COG3540	Alkaline phosphatase
IXO630_013545	COG0357	Ribosomal RNA small subunit methyltransferase G
IXO630_013570	COG2159	amidohydrolase
IXO630_013580	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IXO630_013585	COG0583	DNA-binding transcription factor activity
IXO630_013590	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IXO630_013605	COG0210	DNA helicase
IXO630_013630	COG0531	amino acid
IXO630_013635	COG1322	Protein conserved in bacteria
IXO630_013645	COG0386	Belongs to the glutathione peroxidase family
IXO630_013705	COG0793	Belongs to the peptidase S41A family
IXO630_013710	COG4942	peptidase
IXO630_013720	COG2234	aminopeptidase activity
IXO630_013765	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IXO630_013770	COG0302	gtp cyclohydrolase
IXO630_013790	COG0477	Major facilitator Superfamily
IXO630_013905	COG3039	Transposase
IXO630_013915	COG1929	Belongs to the glycerate kinase type-1 family
IXO630_013920	COG2271	Major facilitator Superfamily
IXO630_013935	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IXO630_013940	COG0861	Integral membrane protein TerC family
IXO630_013955	COG0584	glycerophosphoryl diester phosphodiesterase
IXO630_013965	COG0671	phosphoesterase, PA-phosphatase related
IXO630_013975	COG0726	polysaccharide deacetylase
IXO630_013980	COG0706	membrane insertase activity
IXO630_013995	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IXO630_014010	COG0187	DNA topoisomerase II activity
IXO630_014020	COG0501	Belongs to the peptidase M48B family
IXO630_014050	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IXO630_014060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IXO630_014070	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
IXO630_014080	COG4772	TonB-dependent receptor
IXO630_014100	COG1304	FMN binding
IXO630_014130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IXO630_014215	COG2826	transposase and inactivated derivatives, IS30 family
IXO630_014240	COG3039	Transposase
IXO630_014250	COG1090	epimerase
IXO630_014260	COG0642	Histidine kinase
IXO630_014270	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IXO630_014380	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IXO630_014455	COG3264	Mechanosensitive ion channel
IXO630_014455	COG1511	domain protein
IXO630_014465	COG3293	Transposase
IXO630_014470	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IXO630_014475	COG2354	Protein conserved in bacteria
IXO630_014480	COG1649	PFAM Uncharacterised BCR, COG1649
IXO630_014500	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IXO630_014525	COG0702	epimerase
IXO630_014540	COG1858	cytochrome C peroxidase
IXO630_014615	COG0513	Belongs to the DEAD box helicase family
IXO630_014620	COG3039	Transposase
IXO630_014665	COG1136	(ABC) transporter
IXO630_014705	COG1136	(ABC) transporter
IXO630_014745	COG1272	protein, Hemolysin III
IXO630_014750	COG1205	dead DEAH box helicase
IXO630_014750	COG1111	helicase
IXO630_014810	COG0067	glutamate synthase
IXO630_014810	COG0069	glutamate synthase activity
IXO630_014810	COG0070	glutamate synthase
IXO630_014815	COG0493	'glutamate synthase
IXO630_014860	COG1609	Transcriptional regulator
IXO630_014890	COG0366	Alpha amylase catalytic
IXO630_014895	COG0366	Alpha amylase catalytic
IXO630_014935	COG0606	chelatase, subunit chli
IXO630_014975	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IXO630_014980	COG1166	arginine decarboxylase activity
IXO630_015055	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IXO630_015080	COG1028	Short-chain dehydrogenase reductase Sdr
IXO630_015105	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
IXO630_015120	COG0210	DNA helicase
IXO630_015135	COG3132	Protein of unknown function, DUF480
IXO630_015140	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
IXO630_015145	COG0284	orotidine-5'-phosphate decarboxylase activity
IXO630_015180	COG2937	Belongs to the GPAT DAPAT family
IXO630_015185	COG0604	alcohol dehydrogenase
IXO630_015185	COG1028	Short-chain dehydrogenase reductase Sdr
IXO630_015185	COG3321	synthase
IXO630_015220	COG3186	Phenylalanine-4-hydroxylase
IXO630_015225	COG1522	sequence-specific DNA binding
IXO630_015270	COG1064	alcohol dehydrogenase
IXO630_015275	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IXO630_015280	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IXO630_015290	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IXO630_015310	COG0676	glucose-6-phosphate 1-epimerase activity
IXO630_015375	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IXO630_015395	COG2853	Lipoprotein
IXO630_015410	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IXO630_015415	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IXO630_015420	COG1127	ABC transporter
IXO630_015495	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IXO630_015500	COG3265	gluconokinase activity
IXO630_015505	COG2211	Major facilitator Superfamily
IXO630_015510	COG3459	Glycosyltransferase 36 associated
IXO630_015520	COG2205	protein histidine kinase activity
IXO630_015530	COG1414	Transcriptional regulator
IXO630_015535	COG0738	Major facilitator superfamily
IXO630_015540	COG3254	rhamnose metabolic process
IXO630_015570	COG0339	signal peptide processing
IXO630_015600	COG0564	pseudouridine synthase activity
IXO630_015610	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IXO630_015620	COG1181	Belongs to the D-alanine--D-alanine ligase family
IXO630_015660	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IXO630_015670	COG0842	Transport permease protein
IXO630_015675	COG1131	(ABC) transporter
IXO630_015705	COG1476	TRANSCRIPTIONal
IXO630_015715	COG4555	ABC transporter
IXO630_015750	COG0625	glutathione transferase activity
IXO630_015795	COG0583	DNA-binding transcription factor activity
IXO630_015835	COG1199	ATP-dependent helicase activity
IXO630_015855	COG1566	PFAM secretion protein HlyD family protein
IXO630_015875	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IXO630_015915	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
IXO630_015915	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
IXO630_015920	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IXO630_015935	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IXO630_015970	COG3237	CsbD-like
IXO630_015975	COG0180	Tryptophanyl-tRNA synthetase
IXO630_015980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IXO630_016025	COG0753	catalase activity
IXO630_016030	COG1595	DNA-templated transcription, initiation
IXO630_016040	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IXO630_016050	COG0628	permease
IXO630_016060	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IXO630_016065	COG1040	competence protein
IXO630_016070	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IXO630_016075	COG0156	8-amino-7-oxononanoate synthase activity
IXO630_016085	COG1028	Short-chain dehydrogenase reductase Sdr
IXO630_016100	COG0463	Glycosyl transferase, family 2
IXO630_016110	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IXO630_016115	COG3100	YcgL domain-containing protein
IXO630_016130	COG3387	PFAM Glycoside hydrolase 15-related
IXO630_016135	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IXO630_016140	COG3039	Transposase
IXO630_016200	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IXO630_016215	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IXO630_016220	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
IXO630_016230	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
IXO630_016235	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IXO630_016240	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IXO630_016290	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IXO630_016305	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
IXO630_016370	COG0358	DNA primase activity
IXO630_016375	COG1295	ribonuclease BN
IXO630_016385	COG1610	YqeY-like protein
IXO630_016395	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IXO630_016400	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IXO630_016440	COG2133	pyrroloquinoline quinone binding
IXO630_016445	COG4682	membrane
IXO630_016470	COG0531	amino acid
IXO630_016500	COG4948	Mandelate Racemase Muconate Lactonizing
IXO630_016510	COG3023	N-Acetylmuramoyl-L-alanine amidase
IXO630_016515	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
IXO630_016585	COG0183	Belongs to the thiolase family
IXO630_016625	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IXO630_016635	COG3483	tryptophan 2,3-dioxygenase activity
IXO630_016640	COG3104	oligopeptide transport
IXO630_016670	COG1320	monovalent cation:proton antiporter activity
IXO630_016675	COG2212	antiporter activity
IXO630_016685	COG0651	ATP synthesis coupled electron transport
IXO630_016690	COG1006	Multisubunit Na H antiporter MnhC subunit
IXO630_016695	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IXO630_016695	COG2111	Na H antiporter
IXO630_016745	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IXO630_016755	COG0456	acetyltransferase
IXO630_016775	COG2801	Transposase and inactivated derivatives
IXO630_016785	COG4221	oxidoreductase activity
IXO630_016830	COG3039	Transposase
IXO630_016850	COG0697	spore germination
IXO630_016855	COG4305	rare lipoprotein A
IXO630_016860	COG5297	Belongs to the glycosyl hydrolase family 6
IXO630_016870	COG1113	amino acid transport
IXO630_016880	COG0598	Magnesium transport protein CorA
IXO630_016950	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IXO630_016950	COG5297	Belongs to the glycosyl hydrolase family 6
IXO630_016955	COG0659	secondary active sulfate transmembrane transporter activity
IXO630_016990	COG3275	phosphorelay sensor kinase activity
IXO630_017000	COG0181	hydroxymethylbilane synthase activity
IXO630_017025	COG1505	serine-type exopeptidase activity
IXO630_017040	COG3039	Transposase
IXO630_017045	COG0436	Aminotransferase
IXO630_017075	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IXO630_017105	COG0308	aminopeptidase N
IXO630_017110	COG2199	diguanylate cyclase activity
IXO630_017160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IXO630_017165	COG1077	Cell shape determining protein MreB Mrl
IXO630_017170	COG1792	Involved in formation and maintenance of cell shape
IXO630_017185	COG0772	Belongs to the SEDS family
IXO630_017220	COG2951	lytic endotransglycosylase activity
IXO630_017225	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IXO630_017230	COG1686	Belongs to the peptidase S11 family
IXO630_017245	COG2921	Belongs to the UPF0250 family
IXO630_017270	COG1051	belongs to the nudix hydrolase family
IXO630_017270	COG1056	cytidyltransferase-related domain
IXO630_017305	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
IXO630_017310	COG0673	inositol 2-dehydrogenase activity
IXO630_017315	COG2823	Periplasmic or secreted lipoprotein
IXO630_017320	COG4251	negative regulation of phosphorylation
IXO630_017325	COG0784	Response regulator, receiver
IXO630_017330	COG4191	Histidine kinase
IXO630_017335	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IXO630_017385	COG3250	beta-galactosidase activity
IXO630_017400	COG2188	Transcriptional regulator
IXO630_017410	COG1609	Transcriptional regulator
IXO630_017415	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IXO630_017420	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IXO630_017430	COG1215	transferase activity, transferring glycosyl groups
IXO630_017435	COG1649	PFAM Uncharacterised BCR, COG1649
IXO630_017435	COG0726	polysaccharide deacetylase
IXO630_017515	COG3039	Transposase
IXO630_017520	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IXO630_017525	COG3039	Transposase
IXO630_017560	COG0218	Necessary for normal cell division and for the maintenance of normal septation
IXO630_017575	COG2205	protein histidine kinase activity
IXO630_017610	COG2205	protein histidine kinase activity
IXO630_017650	COG3039	Transposase
IXO630_017665	COG0488	(ABC) transporter
IXO630_017685	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IXO630_017705	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IXO630_017705	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IXO630_017725	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
IXO630_017730	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IXO630_017735	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IXO630_017755	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IXO630_017760	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
IXO630_017770	COG2205	protein histidine kinase activity
IXO630_017775	COG0745	RESPONSE REGULATOR receiver
IXO630_017780	COG0277	FAD linked oxidase domain protein
IXO630_017785	COG1988	membrane-bound metal-dependent
IXO630_017790	COG0792	nuclease activity
IXO630_017825	COG0275	rRNA processing
IXO630_017830	COG3116	cell division
IXO630_017845	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IXO630_017850	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IXO630_017865	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IXO630_017870	COG1181	Belongs to the D-alanine--D-alanine ligase family
IXO630_017875	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IXO630_017890	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
IXO630_017900	COG1388	LysM domain
IXO630_017900	COG4942	peptidase
IXO630_017905	COG0653	protein targeting
IXO630_017915	COG0494	nUDIX hydrolase
IXO630_017930	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IXO630_017940	COG0604	alcohol dehydrogenase
IXO630_017940	COG3321	synthase
IXO630_017940	COG1028	Short-chain dehydrogenase reductase Sdr
IXO630_017990	COG2226	methyltransferase
IXO630_017995	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IXO630_018030	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IXO630_018035	COG3039	Transposase
IXO630_018050	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IXO630_018060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IXO630_018065	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IXO630_018075	COG3039	Transposase
IXO630_018095	COG0667	Aldo Keto reductase
IXO630_018150	COG2175	clavaminate synthase activity
IXO630_018160	COG4181	ATPase activity
IXO630_018175	COG0642	Histidine kinase
IXO630_018200	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IXO630_018220	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IXO630_018245	COG2967	ApaG domain
IXO630_018250	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IXO630_018260	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IXO630_018275	COG0123	including yeast histone deacetylase and acetoin utilization protein
IXO630_018280	COG2096	Adenosyltransferase
IXO630_018290	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IXO630_018295	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IXO630_018335	COG0583	DNA-binding transcription factor activity
IXO630_018340	COG0318	PFAM AMP-dependent synthetase and ligase
IXO630_018350	COG1024	Enoyl-CoA hydratase
IXO630_018370	COG3386	PFAM SMP-30 Gluconolaconase
IXO630_018485	COG1902	pentaerythritol trinitrate reductase activity
IXO630_018485	COG0446	pyridine nucleotide-disulphide oxidoreductase
IXO630_018490	COG0604	alcohol dehydrogenase
IXO630_018515	COG0156	8-amino-7-oxononanoate synthase activity
IXO630_018520	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IXO630_018525	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IXO630_018530	COG4208	sulfate ABC transporter
IXO630_018535	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IXO630_018565	COG0588	phosphoglycerate mutase activity
IXO630_018575	COG0285	dihydrofolate synthase activity
IXO630_018595	COG2833	Protein of unknown function (DUF455)
IXO630_018615	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IXO630_018620	COG0671	phosphoesterase, PA-phosphatase related
IXO630_018625	COG0438	transferase activity, transferring glycosyl groups
IXO630_018635	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IXO630_018650	COG4783	chaperone-mediated protein folding
IXO630_018675	COG0473	3-isopropylmalate dehydrogenase activity
IXO630_018725	COG0544	peptidyl-prolyl cis-trans isomerase activity
IXO630_018765	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IXO630_018805	COG0631	protein serine/threonine phosphatase activity
IXO630_018875	COG0582	viral genome integration into host DNA
IXO630_018885	COG0859	PFAM glycosyl transferase family 9
IXO630_018890	COG3642	lipopolysaccharide core region biosynthetic process
IXO630_018895	COG1234	tRNA 3'-trailer cleavage
IXO630_018900	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IXO630_018910	COG0315	cyclic pyranopterin monophosphate synthase activity
IXO630_018915	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IXO630_018920	COG0314	molybdopterin synthase activity
IXO630_018950	COG0537	adenosine 5'-monophosphoramidase activity
IXO630_018970	COG0714	Associated with various cellular activities
IXO630_018990	COG0242	peptide deformylase activity
IXO630_019070	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IXO630_019075	COG0726	polysaccharide deacetylase
IXO630_019100	COG1162	GTPase activity
IXO630_019125	COG2211	Major facilitator Superfamily
IXO630_019135	COG1609	Transcriptional regulator
IXO630_019140	COG1028	Short-chain dehydrogenase reductase Sdr
IXO630_019145	COG2851	Citrate transporter
IXO630_019160	COG0642	Histidine kinase
IXO630_019170	COG2197	response regulator
IXO630_019185	COG0583	DNA-binding transcription factor activity
IXO630_019200	COG4191	Histidine kinase
IXO630_019220	COG0280	phosphate acetyltransferase
IXO630_019220	COG0281	malic enzyme
IXO630_019290	COG0352	thiamine-phosphate diphosphorylase activity
IXO630_019295	COG1773	rubredoxin
IXO630_019300	COG2912	Transglutaminase-like superfamily
IXO630_019310	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IXO630_019320	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IXO630_019345	COG0006	proline dipeptidase activity
IXO630_019380	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IXO630_019395	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IXO630_019400	COG1561	YicC-like family, N-terminal region
IXO630_019425	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IXO630_019435	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IXO630_019460	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
IXO630_019505	COG0714	Associated with various cellular activities
IXO630_019525	COG2304	oxidoreductase activity
IXO630_019545	COG1301	dicarboxylic acid transport
IXO630_019550	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IXO630_019560	COG0739	heme binding
IXO630_019565	COG1376	ErfK ybiS ycfS ynhG family protein
IXO630_019590	COG1022	Amp-dependent synthetase and ligase
IXO630_019600	COG1028	Short-chain dehydrogenase reductase Sdr
IXO630_019615	COG0642	Histidine kinase
IXO630_019635	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IXO630_019640	COG4149	molybdate abc transporter
IXO630_019645	COG0725	ABC transporter, periplasmic molybdate-binding protein
IXO630_019650	COG3453	Protein conserved in bacteria
IXO630_019650	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IXO630_019690	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IXO630_019710	COG2205	protein histidine kinase activity
IXO630_019715	COG0745	RESPONSE REGULATOR receiver
IXO630_019770	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IXO630_019775	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IXO630_019825	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IXO630_019840	COG2801	Transposase and inactivated derivatives
IXO630_019880	COG2201	protein-glutamate methylesterase activity
IXO630_019910	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IXO630_019920	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IXO630_019925	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IXO630_019940	COG1842	Phage shock protein A
IXO630_019965	COG0754	glutathionylspermidine amidase activity
IXO630_020020	COG0531	amino acid
IXO630_020025	COG2197	response regulator
IXO630_020040	COG1113	amino acid transport
IXO630_020055	COG1271	oxidase subunit
IXO630_020060	COG1294	oxidase, subunit
IXO630_020070	COG2239	Acts as a magnesium transporter
IXO630_020075	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IXO630_020080	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IXO630_020095	COG1660	Displays ATPase and GTPase activities
IXO630_020100	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IXO630_020105	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IXO630_020120	COG1137	ATPase activity
IXO630_020125	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IXO630_020135	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IXO630_020145	COG0271	Belongs to the BolA IbaG family
IXO630_020150	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IXO630_020170	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IXO630_020185	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IXO630_020195	COG0628	permease
IXO630_020205	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IXO630_020210	COG3178	'Phosphotransferase
IXO630_020225	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IXO630_020230	COG1555	photosystem II stabilization
IXO630_020280	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IXO630_020290	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IXO630_020310	COG0228	four-way junction DNA binding
IXO630_020315	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IXO630_020320	COG0336	Belongs to the RNA methyltransferase TrmD family
IXO630_020335	COG0534	Mate efflux family protein
IXO630_020370	COG0542	response to heat
IXO630_020405	COG4206	TonB-dependent receptor
IXO630_020465	COG0019	diaminopimelate decarboxylase activity
IXO630_020475	COG2814	Major facilitator Superfamily
IXO630_020480	COG4264	IucA IucC family
IXO630_020490	COG4772	TonB-dependent receptor
IXO630_020505	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IXO630_020505	COG4651	solute:proton antiporter activity
IXO630_020545	COG0488	(ABC) transporter
IXO630_020570	COG2755	lipolytic protein G-D-S-L family
IXO630_020570	COG0657	acetylesterase activity
IXO630_020615	COG2207	Transcriptional regulator
IXO630_020620	COG0326	Molecular chaperone. Has ATPase activity
IXO630_020650	COG0174	glutamine synthetase
IXO630_020655	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
IXO630_020665	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IXO630_020680	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IXO630_020705	COG2146	nitrite reductase [NAD(P)H] activity
IXO630_020720	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IXO630_020725	COG0719	Fe-S assembly protein
IXO630_020730	COG0396	ATPase activity
IXO630_020735	COG0719	Fe-S assembly protein
IXO630_020740	COG1959	2 iron, 2 sulfur cluster binding
IXO630_020760	COG0693	protein deglycase activity
IXO630_020800	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IXO630_020830	COG0519	Catalyzes the synthesis of GMP from XMP
IXO630_020840	COG1678	Uncharacterized ACR, COG1678
IXO630_020845	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IXO630_020875	COG1764	response to oxidative stress
IXO630_020885	COG0384	phenazine biosynthesis protein PhzF
IXO630_020895	COG0527	aspartate kinase activity
IXO630_020920	COG0142	geranyltranstransferase activity
IXO630_020925	COG0629	single-stranded DNA binding
IXO630_020930	COG4251	negative regulation of phosphorylation
IXO630_020930	COG2203	Gaf domain
IXO630_020930	COG5001	Diguanylate cyclase
IXO630_020930	COG3706	GGDEF domain
IXO630_020960	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IXO630_021005	COG2879	small protein
IXO630_021010	COG1966	Carbon starvation protein
IXO630_021015	COG1741	Belongs to the pirin family
IXO630_021070	COG3328	transposase activity
IXO630_021085	COG3179	chitinase
IXO630_021110	COG3039	Transposase
IXO630_021135	COG3179	chitinase
IXO630_021270	COG3039	Transposase
IXO630_021275	COG3039	Transposase
IXO630_021355	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
IXO630_021360	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
IXO630_021365	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
IXO630_021370	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
IXO630_021405	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IXO630_021410	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IXO630_021445	COG0587	DNA-directed DNA polymerase activity
IXO630_021460	COG1297	OPT oligopeptide transporter protein
IXO630_021480	COG0823	Involved in the tonB-independent uptake of proteins
IXO630_021480	COG1506	peptidase
IXO630_021500	COG2207	Transcriptional regulator
IXO630_021500	COG1917	Cupin 2, conserved barrel domain protein
IXO630_021525	COG0753	catalase activity
IXO630_021565	COG0469	pyruvate kinase activity
IXO630_021570	COG3588	fructose-bisphosphate aldolase
IXO630_021575	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
IXO630_021625	COG0784	Response regulator, receiver
IXO630_021625	COG2198	Histidine kinase
IXO630_021625	COG2205	protein histidine kinase activity
IXO630_021645	COG0175	sulfate reduction
IXO630_021650	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IXO630_021655	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IXO630_021660	COG0175	sulfate reduction
IXO630_021665	COG2895	sulfate adenylyltransferase (ATP) activity
IXO630_021665	COG0529	Catalyzes the synthesis of activated sulfate
IXO630_021675	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IXO630_021680	COG0308	aminopeptidase N
IXO630_021700	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IXO630_021720	COG1970	mechanosensitive ion channel activity
IXO630_021750	COG3273	potassium ion transport
IXO630_021750	COG0471	metal ion transport
IXO630_021760	COG2022	thiamine diphosphate biosynthetic process
IXO630_021855	COG3039	Transposase
IXO630_021895	COG3039	Transposase
IXO630_021930	COG3118	belongs to the thioredoxin family
IXO630_021955	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IXO630_021980	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IXO630_022010	COG2968	Membrane
IXO630_022025	COG3164	Protein of unknown function
IXO630_022035	COG0312	modulator of DNA gyrase
IXO630_022040	COG3028	Belongs to the UPF0307 family
IXO630_022045	COG0312	modulator of DNA gyrase
IXO630_022070	COG0142	geranyltranstransferase activity
IXO630_022075	COG1722	exodeoxyribonuclease VII activity
IXO630_022080	COG0037	tRNA processing
IXO630_022085	COG1785	Belongs to the alkaline phosphatase family
IXO630_022090	COG1301	dicarboxylic acid transport
IXO630_022105	COG0791	NLP P60 protein
IXO630_022110	COG0791	NLP P60 protein
IXO630_022115	COG1047	Peptidyl-prolyl cis-trans
IXO630_022120	COG2311	Membrane
IXO630_022125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IXO630_022165	COG0489	protein tyrosine kinase activity
IXO630_022170	COG0717	Belongs to the dCTP deaminase family
IXO630_022190	COG0412	Dienelactone hydrolase
IXO630_022200	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IXO630_022240	COG2890	protein-(glutamine-N5) methyltransferase activity
IXO630_022245	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IXO630_022250	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IXO630_022255	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IXO630_022275	COG0101	tRNA pseudouridine synthase activity
IXO630_022280	COG0135	phosphoribosylanthranilate isomerase activity
IXO630_022300	COG0159	tryptophan synthase activity
IXO630_022305	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IXO630_022310	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IXO630_022360	COG0149	triose-phosphate isomerase activity
IXO630_022375	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IXO630_022385	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IXO630_022390	COG0649	NAD binding
IXO630_022395	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
IXO630_022400	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IXO630_022405	COG1034	ATP synthesis coupled electron transport
IXO630_022410	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
IXO630_022440	COG1007	ATP synthesis coupled electron transport
IXO630_022450	COG0779	Required for maturation of 30S ribosomal subunits
IXO630_022455	COG0195	Participates in both transcription termination and antitermination
IXO630_022475	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IXO630_022480	COG1185	polyribonucleotide nucleotidyltransferase activity
IXO630_022515	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IXO630_022525	COG2095	MarC family integral membrane protein
IXO630_022540	COG1611	Belongs to the LOG family
IXO630_022655	COG1192	Involved in chromosome partitioning
IXO630_022750	COG3179	chitinase
IXO630_022795	COG4695	Portal protein
IXO630_022860	COG4969	Belongs to the N-Me-Phe pilin family
IXO630_022865	COG0556	nucleotide-excision repair
IXO630_022900	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IXO630_022915	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IXO630_022970	COG0438	transferase activity, transferring glycosyl groups
IXO630_022975	COG0438	transferase activity, transferring glycosyl groups
IXO630_022985	COG0438	transferase activity, transferring glycosyl groups
IXO630_023025	COG3040	lipid binding
IXO630_023055	COG3039	Transposase
IXO630_023120	COG4191	Histidine kinase
IXO630_023120	COG0784	Response regulator, receiver
IXO630_023140	COG0552	protein localization to endoplasmic reticulum
IXO630_023150	COG3938	Belongs to the proline racemase family
IXO630_023155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IXO630_023170	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IXO630_023180	COG0006	proline dipeptidase activity
IXO630_023195	COG0531	amino acid
IXO630_023245	COG4206	TonB-dependent receptor
IXO630_023330	COG0746	molybdenum cofactor guanylyltransferase activity
IXO630_023355	COG1648	precorrin-2 dehydrogenase activity
IXO630_023355	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IXO630_023400	COG3039	Transposase
IXO630_023410	COG3039	Transposase
IXO630_023450	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IXO630_023470	COG1054	Belongs to the UPF0176 family
IXO630_023485	COG1530	ribonuclease E activity
IXO630_023495	COG3064	Membrane
IXO630_023500	COG0428	transporter
IXO630_023505	COG0428	transporter
IXO630_023515	COG2154	pterin-4-alpha-carbinolamine dehydratase
IXO630_023580	COG3039	Transposase
IXO630_023700	COG0631	protein serine/threonine phosphatase activity
IXO630_023705	COG0515	serine threonine protein kinase
IXO630_023735	COG1858	cytochrome C peroxidase
IXO630_023790	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family