locus-tag	class	description
IXO704_000015	COG1192	Involved in chromosome partitioning
IXO704_000020	COG1475	DNA binding
IXO704_000050	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IXO704_000065	COG0741	lytic transglycosylase activity
IXO704_000080	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
IXO704_000085	COG2948	multi-organism process
IXO704_000100	COG3704	protein secretion by the type IV secretion system
IXO704_000115	COG3451	type IV secretory pathway VirB4
IXO704_000155	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IXO704_000175	COG0187	DNA topoisomerase II activity
IXO704_000185	COG0501	Belongs to the peptidase M48B family
IXO704_000215	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IXO704_000225	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IXO704_000235	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
IXO704_000245	COG4772	TonB-dependent receptor
IXO704_000265	COG1304	FMN binding
IXO704_000295	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IXO704_000385	COG2826	transposase and inactivated derivatives, IS30 family
IXO704_000410	COG3039	Transposase
IXO704_000420	COG1090	epimerase
IXO704_000430	COG0642	Histidine kinase
IXO704_000440	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IXO704_000545	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IXO704_000625	COG1511	domain protein
IXO704_000625	COG3264	Mechanosensitive ion channel
IXO704_000640	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IXO704_000650	COG2354	Protein conserved in bacteria
IXO704_000675	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IXO704_000700	COG0702	epimerase
IXO704_000715	COG1858	cytochrome C peroxidase
IXO704_000800	COG0513	Belongs to the DEAD box helicase family
IXO704_000810	COG3039	Transposase
IXO704_000860	COG1136	(ABC) transporter
IXO704_000885	COG1136	(ABC) transporter
IXO704_000930	COG1272	protein, Hemolysin III
IXO704_000935	COG1111	helicase
IXO704_000935	COG1205	dead DEAH box helicase
IXO704_001000	COG0070	glutamate synthase
IXO704_001000	COG0069	glutamate synthase activity
IXO704_001000	COG0067	glutamate synthase
IXO704_001005	COG0493	'glutamate synthase
IXO704_001050	COG1609	Transcriptional regulator
IXO704_001085	COG0366	Alpha amylase catalytic
IXO704_001090	COG0366	Alpha amylase catalytic
IXO704_001140	COG0606	chelatase, subunit chli
IXO704_001185	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IXO704_001190	COG1166	arginine decarboxylase activity
IXO704_001205	COG3501	Rhs element vgr protein
IXO704_001300	COG1028	Short-chain dehydrogenase reductase Sdr
IXO704_001325	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
IXO704_001340	COG0210	DNA helicase
IXO704_001355	COG3132	Protein of unknown function, DUF480
IXO704_001360	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
IXO704_001365	COG0284	orotidine-5'-phosphate decarboxylase activity
IXO704_001405	COG0604	alcohol dehydrogenase
IXO704_001405	COG3321	synthase
IXO704_001405	COG1028	Short-chain dehydrogenase reductase Sdr
IXO704_001430	COG2755	lipolytic protein G-D-S-L family
IXO704_001445	COG3186	Phenylalanine-4-hydroxylase
IXO704_001450	COG1522	sequence-specific DNA binding
IXO704_001500	COG1064	alcohol dehydrogenase
IXO704_001510	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IXO704_001520	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IXO704_001530	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IXO704_001555	COG0676	glucose-6-phosphate 1-epimerase activity
IXO704_001625	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IXO704_001650	COG2853	Lipoprotein
IXO704_001665	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IXO704_001670	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IXO704_001675	COG1127	ABC transporter
IXO704_001755	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IXO704_001765	COG3265	gluconokinase activity
IXO704_001770	COG2211	Major facilitator Superfamily
IXO704_001775	COG3459	Glycosyltransferase 36 associated
IXO704_001785	COG2205	protein histidine kinase activity
IXO704_001795	COG1414	Transcriptional regulator
IXO704_001800	COG0738	Major facilitator superfamily
IXO704_001805	COG3254	rhamnose metabolic process
IXO704_001835	COG0339	signal peptide processing
IXO704_001865	COG0564	pseudouridine synthase activity
IXO704_001875	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IXO704_001890	COG1181	Belongs to the D-alanine--D-alanine ligase family
IXO704_001940	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IXO704_001950	COG0842	Transport permease protein
IXO704_001955	COG1131	(ABC) transporter
IXO704_001980	COG1476	TRANSCRIPTIONal
IXO704_001990	COG4555	ABC transporter
IXO704_002025	COG0625	glutathione transferase activity
IXO704_002075	COG0583	DNA-binding transcription factor activity
IXO704_002110	COG1199	ATP-dependent helicase activity
IXO704_002130	COG1566	PFAM secretion protein HlyD family protein
IXO704_002160	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IXO704_002170	COG0745	RESPONSE REGULATOR receiver
IXO704_002175	COG2205	protein histidine kinase activity
IXO704_002200	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
IXO704_002200	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
IXO704_002205	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IXO704_002220	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IXO704_002260	COG3237	CsbD-like
IXO704_002265	COG0180	Tryptophanyl-tRNA synthetase
IXO704_002270	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IXO704_002320	COG0753	catalase activity
IXO704_002325	COG1595	DNA-templated transcription, initiation
IXO704_002335	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IXO704_002345	COG0628	permease
IXO704_002360	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IXO704_002365	COG1040	competence protein
IXO704_002370	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IXO704_002375	COG0156	8-amino-7-oxononanoate synthase activity
IXO704_002390	COG1028	Short-chain dehydrogenase reductase Sdr
IXO704_002405	COG0463	Glycosyl transferase, family 2
IXO704_002415	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IXO704_002420	COG3100	YcgL domain-containing protein
IXO704_002440	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IXO704_002445	COG3039	Transposase
IXO704_002520	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IXO704_002535	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IXO704_002540	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
IXO704_002550	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
IXO704_002555	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IXO704_002560	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IXO704_002610	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IXO704_002625	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
IXO704_002695	COG0358	DNA primase activity
IXO704_002700	COG1295	ribonuclease BN
IXO704_002715	COG1610	YqeY-like protein
IXO704_002725	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IXO704_002730	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IXO704_002775	COG2133	pyrroloquinoline quinone binding
IXO704_002780	COG4682	membrane
IXO704_002805	COG0531	amino acid
IXO704_002835	COG4948	Mandelate Racemase Muconate Lactonizing
IXO704_002845	COG3023	N-Acetylmuramoyl-L-alanine amidase
IXO704_002850	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
IXO704_002925	COG0183	Belongs to the thiolase family
IXO704_002965	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IXO704_002975	COG3483	tryptophan 2,3-dioxygenase activity
IXO704_002980	COG3104	oligopeptide transport
IXO704_003010	COG1320	monovalent cation:proton antiporter activity
IXO704_003015	COG2212	antiporter activity
IXO704_003025	COG0651	ATP synthesis coupled electron transport
IXO704_003030	COG1006	Multisubunit Na H antiporter MnhC subunit
IXO704_003035	COG2111	Na H antiporter
IXO704_003035	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IXO704_003085	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IXO704_003095	COG0456	acetyltransferase
IXO704_003115	COG2801	Transposase and inactivated derivatives
IXO704_003125	COG4221	oxidoreductase activity
IXO704_003170	COG3039	Transposase
IXO704_003190	COG0697	spore germination
IXO704_003195	COG4305	rare lipoprotein A
IXO704_003200	COG5297	Belongs to the glycosyl hydrolase family 6
IXO704_003210	COG1113	amino acid transport
IXO704_003220	COG0598	Magnesium transport protein CorA
IXO704_003295	COG5297	Belongs to the glycosyl hydrolase family 6
IXO704_003295	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IXO704_003300	COG0659	secondary active sulfate transmembrane transporter activity
IXO704_003340	COG3275	phosphorelay sensor kinase activity
IXO704_003350	COG0181	hydroxymethylbilane synthase activity
IXO704_003375	COG1505	serine-type exopeptidase activity
IXO704_003390	COG3039	Transposase
IXO704_003425	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IXO704_003455	COG0308	aminopeptidase N
IXO704_003460	COG2199	diguanylate cyclase activity
IXO704_003510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IXO704_003515	COG1077	Cell shape determining protein MreB Mrl
IXO704_003520	COG1792	Involved in formation and maintenance of cell shape
IXO704_003535	COG0772	Belongs to the SEDS family
IXO704_003545	COG3501	Rhs element vgr protein
IXO704_003570	COG2951	lytic endotransglycosylase activity
IXO704_003575	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IXO704_003580	COG1686	Belongs to the peptidase S11 family
IXO704_003595	COG2921	Belongs to the UPF0250 family
IXO704_003620	COG1051	belongs to the nudix hydrolase family
IXO704_003620	COG1056	cytidyltransferase-related domain
IXO704_003655	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
IXO704_003660	COG0673	inositol 2-dehydrogenase activity
IXO704_003665	COG2823	Periplasmic or secreted lipoprotein
IXO704_003670	COG4251	negative regulation of phosphorylation
IXO704_003675	COG0784	Response regulator, receiver
IXO704_003680	COG4191	Histidine kinase
IXO704_003685	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IXO704_003735	COG3250	beta-galactosidase activity
IXO704_003750	COG2188	Transcriptional regulator
IXO704_003760	COG1609	Transcriptional regulator
IXO704_003765	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IXO704_003770	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IXO704_003780	COG1215	transferase activity, transferring glycosyl groups
IXO704_003785	COG1649	PFAM Uncharacterised BCR, COG1649
IXO704_003785	COG0726	polysaccharide deacetylase
IXO704_003880	COG3039	Transposase
IXO704_003895	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IXO704_003900	COG3039	Transposase
IXO704_003935	COG0218	Necessary for normal cell division and for the maintenance of normal septation
IXO704_003950	COG2205	protein histidine kinase activity
IXO704_003985	COG2205	protein histidine kinase activity
IXO704_003990	COG0745	RESPONSE REGULATOR receiver
IXO704_004030	COG3039	Transposase
IXO704_004045	COG0488	(ABC) transporter
IXO704_004065	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IXO704_004085	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IXO704_004085	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IXO704_004105	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
IXO704_004110	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IXO704_004115	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IXO704_004140	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IXO704_004145	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
IXO704_004155	COG2205	protein histidine kinase activity
IXO704_004160	COG0745	RESPONSE REGULATOR receiver
IXO704_004165	COG0277	FAD linked oxidase domain protein
IXO704_004170	COG1988	membrane-bound metal-dependent
IXO704_004175	COG0792	nuclease activity
IXO704_004210	COG0275	rRNA processing
IXO704_004215	COG3116	cell division
IXO704_004230	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IXO704_004235	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IXO704_004250	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IXO704_004255	COG1181	Belongs to the D-alanine--D-alanine ligase family
IXO704_004260	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IXO704_004275	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
IXO704_004285	COG1388	LysM domain
IXO704_004285	COG4942	peptidase
IXO704_004290	COG0653	protein targeting
IXO704_004300	COG0494	nUDIX hydrolase
IXO704_004315	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IXO704_004330	COG0604	alcohol dehydrogenase
IXO704_004330	COG3321	synthase
IXO704_004330	COG1028	Short-chain dehydrogenase reductase Sdr
IXO704_004390	COG2226	methyltransferase
IXO704_004395	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IXO704_004435	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IXO704_004440	COG3039	Transposase
IXO704_004455	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IXO704_004470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IXO704_004475	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IXO704_004485	COG3039	Transposase
IXO704_004510	COG0667	Aldo Keto reductase
IXO704_004565	COG2175	clavaminate synthase activity
IXO704_004575	COG4181	ATPase activity
IXO704_004590	COG0642	Histidine kinase
IXO704_004610	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IXO704_004630	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IXO704_004655	COG2967	ApaG domain
IXO704_004660	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IXO704_004670	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IXO704_004685	COG0123	including yeast histone deacetylase and acetoin utilization protein
IXO704_004690	COG2096	Adenosyltransferase
IXO704_004700	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IXO704_004705	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IXO704_004745	COG0583	DNA-binding transcription factor activity
IXO704_004750	COG0318	PFAM AMP-dependent synthetase and ligase
IXO704_004760	COG1024	Enoyl-CoA hydratase
IXO704_004780	COG3386	PFAM SMP-30 Gluconolaconase
IXO704_004910	COG1902	pentaerythritol trinitrate reductase activity
IXO704_004910	COG0446	pyridine nucleotide-disulphide oxidoreductase
IXO704_004915	COG0604	alcohol dehydrogenase
IXO704_004945	COG0156	8-amino-7-oxononanoate synthase activity
IXO704_004950	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IXO704_004955	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IXO704_004960	COG4208	sulfate ABC transporter
IXO704_004965	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IXO704_005000	COG0588	phosphoglycerate mutase activity
IXO704_005010	COG0285	dihydrofolate synthase activity
IXO704_005030	COG2833	Protein of unknown function (DUF455)
IXO704_005050	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IXO704_005055	COG0671	phosphoesterase, PA-phosphatase related
IXO704_005060	COG0438	transferase activity, transferring glycosyl groups
IXO704_005070	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IXO704_005085	COG4783	chaperone-mediated protein folding
IXO704_005110	COG0473	3-isopropylmalate dehydrogenase activity
IXO704_005165	COG0544	peptidyl-prolyl cis-trans isomerase activity
IXO704_005205	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IXO704_005235	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IXO704_005245	COG0631	protein serine/threonine phosphatase activity
IXO704_005270	COG3501	Rhs element vgr protein
IXO704_005315	COG0582	viral genome integration into host DNA
IXO704_005325	COG0859	PFAM glycosyl transferase family 9
IXO704_005330	COG3642	lipopolysaccharide core region biosynthetic process
IXO704_005335	COG1234	tRNA 3'-trailer cleavage
IXO704_005340	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IXO704_005350	COG0315	cyclic pyranopterin monophosphate synthase activity
IXO704_005355	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IXO704_005360	COG0314	molybdopterin synthase activity
IXO704_005390	COG0537	adenosine 5'-monophosphoramidase activity
IXO704_005410	COG0714	Associated with various cellular activities
IXO704_005430	COG0242	peptide deformylase activity
IXO704_005515	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IXO704_005545	COG1162	GTPase activity
IXO704_005570	COG2211	Major facilitator Superfamily
IXO704_005580	COG1609	Transcriptional regulator
IXO704_005585	COG1028	Short-chain dehydrogenase reductase Sdr
IXO704_005590	COG2851	Citrate transporter
IXO704_005620	COG2197	response regulator
IXO704_005640	COG0583	DNA-binding transcription factor activity
IXO704_005655	COG4191	Histidine kinase
IXO704_005675	COG0280	phosphate acetyltransferase
IXO704_005675	COG0281	malic enzyme
IXO704_005750	COG0352	thiamine-phosphate diphosphorylase activity
IXO704_005755	COG1773	rubredoxin
IXO704_005760	COG2912	Transglutaminase-like superfamily
IXO704_005770	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IXO704_005780	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IXO704_005805	COG0006	proline dipeptidase activity
IXO704_005835	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IXO704_005850	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IXO704_005855	COG1561	YicC-like family, N-terminal region
IXO704_005880	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IXO704_005890	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IXO704_005915	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
IXO704_005960	COG0714	Associated with various cellular activities
IXO704_005980	COG2304	oxidoreductase activity
IXO704_006000	COG1301	dicarboxylic acid transport
IXO704_006005	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IXO704_006015	COG0739	heme binding
IXO704_006020	COG1376	ErfK ybiS ycfS ynhG family protein
IXO704_006045	COG1022	Amp-dependent synthetase and ligase
IXO704_006055	COG1028	Short-chain dehydrogenase reductase Sdr
IXO704_006065	COG0745	RESPONSE REGULATOR receiver
IXO704_006070	COG0642	Histidine kinase
IXO704_006090	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IXO704_006095	COG4149	molybdate abc transporter
IXO704_006100	COG0725	ABC transporter, periplasmic molybdate-binding protein
IXO704_006105	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IXO704_006105	COG3453	Protein conserved in bacteria
IXO704_006140	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IXO704_006160	COG2205	protein histidine kinase activity
IXO704_006165	COG0745	RESPONSE REGULATOR receiver
IXO704_006215	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IXO704_006220	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IXO704_006265	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IXO704_006280	COG2801	Transposase and inactivated derivatives
IXO704_006325	COG2201	protein-glutamate methylesterase activity
IXO704_006360	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IXO704_006370	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IXO704_006375	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IXO704_006390	COG1842	Phage shock protein A
IXO704_006415	COG0754	glutathionylspermidine amidase activity
IXO704_006485	COG0531	amino acid
IXO704_006490	COG2197	response regulator
IXO704_006505	COG1113	amino acid transport
IXO704_006525	COG1271	oxidase subunit
IXO704_006530	COG1294	oxidase, subunit
IXO704_006540	COG2239	Acts as a magnesium transporter
IXO704_006550	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IXO704_006555	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IXO704_006565	COG1660	Displays ATPase and GTPase activities
IXO704_006570	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IXO704_006575	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IXO704_006590	COG1137	ATPase activity
IXO704_006595	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IXO704_006605	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IXO704_006615	COG0271	Belongs to the BolA IbaG family
IXO704_006625	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IXO704_006645	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IXO704_006660	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IXO704_006670	COG0628	permease
IXO704_006680	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IXO704_006685	COG3178	'Phosphotransferase
IXO704_006700	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IXO704_006705	COG1555	photosystem II stabilization
IXO704_006755	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IXO704_006765	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IXO704_006790	COG0228	four-way junction DNA binding
IXO704_006795	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IXO704_006800	COG0336	Belongs to the RNA methyltransferase TrmD family
IXO704_006815	COG0534	Mate efflux family protein
IXO704_006855	COG0542	response to heat
IXO704_006895	COG4206	TonB-dependent receptor
IXO704_006955	COG0019	diaminopimelate decarboxylase activity
IXO704_006965	COG2814	Major facilitator Superfamily
IXO704_006970	COG4264	IucA IucC family
IXO704_006980	COG4772	TonB-dependent receptor
IXO704_006995	COG4651	solute:proton antiporter activity
IXO704_006995	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IXO704_007035	COG0488	(ABC) transporter
IXO704_007060	COG2755	lipolytic protein G-D-S-L family
IXO704_007060	COG0657	acetylesterase activity
IXO704_007100	COG2207	Transcriptional regulator
IXO704_007105	COG0326	Molecular chaperone. Has ATPase activity
IXO704_007135	COG3328	transposase activity
IXO704_007140	COG0174	glutamine synthetase
IXO704_007145	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
IXO704_007155	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IXO704_007170	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IXO704_007195	COG2146	nitrite reductase [NAD(P)H] activity
IXO704_007205	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IXO704_007210	COG0719	Fe-S assembly protein
IXO704_007215	COG0396	ATPase activity
IXO704_007220	COG0719	Fe-S assembly protein
IXO704_007225	COG1959	2 iron, 2 sulfur cluster binding
IXO704_007245	COG0693	protein deglycase activity
IXO704_007290	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IXO704_007325	COG0519	Catalyzes the synthesis of GMP from XMP
IXO704_007335	COG1678	Uncharacterized ACR, COG1678
IXO704_007340	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IXO704_007370	COG1764	response to oxidative stress
IXO704_007380	COG0384	phenazine biosynthesis protein PhzF
IXO704_007390	COG0527	aspartate kinase activity
IXO704_007420	COG0142	geranyltranstransferase activity
IXO704_007425	COG0629	single-stranded DNA binding
IXO704_007430	COG2203	Gaf domain
IXO704_007430	COG5001	Diguanylate cyclase
IXO704_007430	COG4251	negative regulation of phosphorylation
IXO704_007430	COG3706	GGDEF domain
IXO704_007470	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IXO704_007525	COG2879	small protein
IXO704_007530	COG1966	Carbon starvation protein
IXO704_007535	COG1741	Belongs to the pirin family
IXO704_007545	COG3501	Rhs element vgr protein
IXO704_007585	COG1741	Belongs to the pirin family
IXO704_007595	COG1515	deoxyribonuclease V activity
IXO704_007600	COG0588	phosphoglycerate mutase activity
IXO704_007615	COG3590	peptidase
IXO704_007630	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IXO704_007635	COG2199	diguanylate cyclase activity
IXO704_007635	COG2202	Pas domain
IXO704_007635	COG2200	EAL domain
IXO704_007640	COG0835	chemotaxis
IXO704_007645	COG0840	transmembrane signaling receptor activity
IXO704_007655	COG2198	Histidine kinase
IXO704_007655	COG0643	Histidine kinase
IXO704_007670	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IXO704_007680	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IXO704_007700	COG2205	protein histidine kinase activity
IXO704_007750	COG3039	Transposase
IXO704_007775	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IXO704_007780	COG0735	belongs to the Fur family
IXO704_007840	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IXO704_007845	COG0084	hydrolase, TatD family'
IXO704_007860	COG1960	acyl-CoA dehydrogenase activity
IXO704_007875	COG0367	asparagine synthase
IXO704_007885	COG0305	Participates in initiation and elongation during chromosome replication
IXO704_007890	COG0415	Belongs to the DNA photolyase family
IXO704_007910	COG1028	Short-chain dehydrogenase reductase Sdr
IXO704_008010	COG5001	Diguanylate cyclase
IXO704_008010	COG5002	protein histidine kinase activity
IXO704_008015	COG1187	pseudouridine synthase activity
IXO704_008040	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IXO704_008050	COG0475	glutathione-regulated potassium exporter activity
IXO704_008055	COG5002	protein histidine kinase activity
IXO704_008055	COG5000	phosphorelay sensor kinase activity
IXO704_008060	COG0745	RESPONSE REGULATOR receiver
IXO704_008090	COG1132	(ABC) transporter
IXO704_008120	COG3039	Transposase
IXO704_008135	COG3039	Transposase
IXO704_008175	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
IXO704_008185	COG4969	Belongs to the N-Me-Phe pilin family
IXO704_008190	COG2194	sulfuric ester hydrolase activity
IXO704_008230	COG0045	succinate-CoA ligase (ADP-forming) activity
IXO704_008235	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IXO704_008245	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IXO704_008245	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IXO704_008250	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IXO704_008255	COG0564	pseudouridine synthase activity
IXO704_008280	COG3387	PFAM Glycoside hydrolase 15-related
IXO704_008285	COG1877	trehalose-phosphatase activity
IXO704_008325	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
IXO704_008340	COG1595	DNA-templated transcription, initiation
IXO704_008350	COG1946	Acyl-CoA thioesterase
IXO704_008365	COG0824	Thioesterase
IXO704_008370	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IXO704_008380	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IXO704_008385	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IXO704_008390	COG0268	Binds directly to 16S ribosomal RNA
IXO704_008395	COG0728	peptidoglycan biosynthetic process
IXO704_008400	COG0196	riboflavin kinase activity
IXO704_008410	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IXO704_008415	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IXO704_008430	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IXO704_008435	COG1845	cytochrome c oxidase, subunit III
IXO704_008440	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IXO704_008450	COG3501	Rhs element vgr protein
IXO704_008460	COG3209	COG3209 Rhs family protein
IXO704_008475	COG3328	transposase activity
IXO704_008610	COG0632	four-way junction helicase activity
IXO704_008620	COG2255	four-way junction helicase activity
IXO704_008625	COG0824	Thioesterase
IXO704_008635	COG0848	biopolymer transport protein
IXO704_008650	COG2885	chlorophyll binding
IXO704_008660	COG0602	queuosine metabolic process
IXO704_008670	COG1187	pseudouridine synthase activity
IXO704_008740	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IXO704_008765	COG0514	ATP-dependent DNA helicase (RecQ)
IXO704_008770	COG0783	Belongs to the Dps family
IXO704_008775	COG1643	Atp-dependent helicase
IXO704_008815	COG0535	radical SAM domain protein
IXO704_008820	COG0535	radical SAM domain protein
IXO704_008840	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IXO704_008850	COG1215	transferase activity, transferring glycosyl groups
IXO704_008855	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IXO704_008865	COG1199	ATP-dependent helicase activity
IXO704_008875	COG1397	ADP-ribosylglycohydrolase
IXO704_008885	COG0189	ligase activity
IXO704_008900	COG0835	chemotaxis
IXO704_008905	COG0840	transmembrane signaling receptor activity
IXO704_008910	COG0643	Histidine kinase
IXO704_008910	COG0784	Response regulator, receiver
IXO704_008910	COG2198	Histidine kinase
IXO704_008935	COG3039	Transposase
IXO704_008970	COG1446	asparaginase
IXO704_009025	COG3537	Alpha-1,2-mannosidase
IXO704_009065	COG1472	Belongs to the glycosyl hydrolase 3 family
IXO704_009085	COG1388	LysM domain
IXO704_009085	COG3858	chitin binding
IXO704_009100	COG0837	glucose binding
IXO704_009105	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IXO704_009115	COG0494	nUDIX hydrolase
IXO704_009125	COG3956	TIGRFAM MazG family protein
IXO704_009140	COG0330	HflC and HflK could
IXO704_009155	COG0509	glycine decarboxylation via glycine cleavage system
IXO704_009170	COG3039	Transposase
IXO704_009200	COG1960	acyl-CoA dehydrogenase activity
IXO704_009210	COG1309	transcriptional regulator
IXO704_009215	COG4771	TonB-dependent receptor
IXO704_009225	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IXO704_009235	COG0463	Glycosyl transferase, family 2
IXO704_009255	COG1272	protein, Hemolysin III
IXO704_009265	COG0739	heme binding
IXO704_009270	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IXO704_009275	COG0626	cystathionine gamma-synthase activity
IXO704_009285	COG1760	l-serine dehydratase
IXO704_009300	COG2353	YceI-like domain
IXO704_009310	COG2353	YceI-like domain
IXO704_009355	COG3250	beta-galactosidase activity
IXO704_009360	COG3867	Arabinogalactan endo-beta-1,4-galactanase
IXO704_009380	COG1960	acyl-CoA dehydrogenase activity
IXO704_009385	COG1024	Enoyl-CoA hydratase
IXO704_009410	COG1024	Enoyl-CoA hydratase
IXO704_009410	COG1250	3-hydroxyacyl-CoA dehydrogenase
IXO704_009425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IXO704_009455	COG1381	Involved in DNA repair and RecF pathway recombination
IXO704_009470	COG2954	triphosphatase activity
IXO704_009480	COG3039	Transposase
IXO704_009485	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IXO704_009490	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
IXO704_009495	COG3046	protein related to deoxyribodipyrimidine photolyase
IXO704_009510	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IXO704_009515	COG1278	Cold shock
IXO704_009535	COG1201	RNA secondary structure unwinding
IXO704_009540	COG1793	dna ligase
IXO704_009550	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
IXO704_009550	COG1793	dna ligase
IXO704_009580	COG0183	Belongs to the thiolase family
IXO704_009615	COG1451	nucleotide metabolic process
IXO704_009630	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IXO704_009670	COG1047	Peptidyl-prolyl cis-trans
IXO704_009685	COG2824	Alkylphosphonate utilization operon protein PhnA
IXO704_009700	COG1902	pentaerythritol trinitrate reductase activity
IXO704_009705	COG2814	Major facilitator Superfamily
IXO704_009745	COG3039	Transposase
IXO704_009775	COG0392	lysyltransferase activity
IXO704_009775	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IXO704_009785	COG0251	oxidation-reduction process
IXO704_009790	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IXO704_009805	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IXO704_009830	COG1595	DNA-templated transcription, initiation
IXO704_009850	COG2878	Part of a membrane complex involved in electron transport
IXO704_009860	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IXO704_009860	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IXO704_009880	COG0833	amino acid
IXO704_009885	COG2040	homocysteine
IXO704_009900	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IXO704_009945	COG0529	Catalyzes the synthesis of activated sulfate
IXO704_009945	COG2895	sulfate adenylyltransferase (ATP) activity
IXO704_010020	COG4771	TonB-dependent receptor
IXO704_010030	COG0825	malonyl-CoA metabolic process
IXO704_010050	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IXO704_010055	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IXO704_010075	COG0750	zinc metalloprotease
IXO704_010085	COG0575	Belongs to the CDS family
IXO704_010095	COG0233	cytoplasmic translational termination
IXO704_010110	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IXO704_010170	COG1393	Belongs to the ArsC family
IXO704_010180	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IXO704_010185	COG0367	asparagine synthase
IXO704_010195	COG4774	siderophore transport
IXO704_010240	COG1566	PFAM secretion protein HlyD family protein
IXO704_010245	COG2814	Major facilitator Superfamily
IXO704_010300	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IXO704_010310	COG1960	acyl-CoA dehydrogenase activity
IXO704_010325	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IXO704_010335	COG2914	Belongs to the UPF0125 (RnfH) family
IXO704_010345	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IXO704_010355	COG0497	DNA recombination
IXO704_010365	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IXO704_010375	COG0484	heat shock protein binding
IXO704_010385	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
IXO704_010390	COG0287	Prephenate dehydrogenase
IXO704_010390	COG1605	Chorismate mutase
IXO704_010410	COG0583	DNA-binding transcription factor activity
IXO704_010425	COG1132	(ABC) transporter
IXO704_010460	COG2850	peptidyl-arginine hydroxylation
IXO704_010540	COG1131	(ABC) transporter
IXO704_010545	COG1725	Transcriptional regulator
IXO704_010555	COG0386	Belongs to the glutathione peroxidase family
IXO704_010570	COG2900	Belongs to the SlyX family
IXO704_010595	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IXO704_010605	COG0646	methionine synthase
IXO704_010605	COG1410	methionine synthase
IXO704_010610	COG1410	methionine synthase
IXO704_010610	COG0646	methionine synthase
IXO704_010615	COG2226	methyltransferase
IXO704_010620	COG1960	acyl-CoA dehydrogenase activity
IXO704_010650	COG0557	exoribonuclease II activity
IXO704_010670	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IXO704_010685	COG3039	Transposase
IXO704_010765	COG3842	ATPase activity
IXO704_010775	COG1177	transmembrane transport
IXO704_010785	COG1012	belongs to the aldehyde dehydrogenase family
IXO704_010800	COG4535	Mg2 and Co2 transporter CorC
IXO704_010820	COG1702	phosphate starvation-inducible protein PhoH
IXO704_010845	COG0741	lytic transglycosylase activity
IXO704_010855	COG0723	plastoquinol--plastocyanin reductase activity
IXO704_010860	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IXO704_010865	COG2857	Cytochrome c1
IXO704_010870	COG0625	glutathione transferase activity
IXO704_010875	COG2969	positive regulation of protein catabolic process
IXO704_010920	COG3328	transposase activity
IXO704_011015	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IXO704_011035	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IXO704_011040	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IXO704_011040	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IXO704_011045	COG0802	atpase or kinase
IXO704_011050	COG0860	N-Acetylmuramoyl-L-alanine amidase
IXO704_011055	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IXO704_011080	COG1028	Short-chain dehydrogenase reductase Sdr
IXO704_011090	COG0501	Belongs to the peptidase M48B family
IXO704_011100	COG2081	HI0933 family
IXO704_011105	COG4681	YaeQ
IXO704_011110	COG1671	Belongs to the UPF0178 family
IXO704_011120	COG0625	glutathione transferase activity
IXO704_011130	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
IXO704_011135	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IXO704_011140	COG0513	Belongs to the DEAD box helicase family
IXO704_011170	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IXO704_011175	COG0483	inositol monophosphate 1-phosphatase activity
IXO704_011190	COG5001	Diguanylate cyclase
IXO704_011190	COG3300	MHYT domain
IXO704_011195	COG1509	lysine 2,3-aminomutase activity
IXO704_011210	COG0402	S-adenosylhomocysteine deaminase activity
IXO704_011215	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IXO704_011240	COG4677	pectinesterase activity
IXO704_011255	COG3039	Transposase
IXO704_011295	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IXO704_011320	COG2166	iron-sulfur cluster assembly
IXO704_011340	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IXO704_011345	COG0137	argininosuccinate synthase activity
IXO704_011355	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IXO704_011360	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IXO704_011375	COG0165	Argininosuccinate lyase
IXO704_011395	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IXO704_011425	COG1271	oxidase subunit
IXO704_011435	COG4988	ABC transporter
IXO704_011440	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IXO704_011530	COG3039	Transposase
IXO704_011545	COG3209	COG3209 Rhs family protein
IXO704_011580	COG3039	Transposase
IXO704_011615	COG0784	Response regulator, receiver
IXO704_011615	COG0643	Histidine kinase
IXO704_011615	COG2198	Histidine kinase
IXO704_011665	COG3300	MHYT domain
IXO704_011665	COG5001	Diguanylate cyclase
IXO704_011670	COG3300	MHYT domain
IXO704_011670	COG5001	Diguanylate cyclase
IXO704_011675	COG1684	flagellar biosynthetic protein fliR
IXO704_011695	COG3190	flagellar
IXO704_011745	COG1677	Flagellar hook-basal body complex protein FliE
IXO704_011780	COG1028	Short-chain dehydrogenase reductase Sdr
IXO704_011790	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IXO704_011810	COG2201	protein-glutamate methylesterase activity
IXO704_011840	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IXO704_011845	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IXO704_011885	COG4787	bacterial-type flagellum-dependent cell motility
IXO704_011895	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
IXO704_011900	COG1558	bacterial-type flagellum-dependent cell motility
IXO704_011910	COG0784	Response regulator, receiver
IXO704_011910	COG0835	chemotaxis
IXO704_011930	COG5002	protein histidine kinase activity
IXO704_011940	COG4585	Histidine kinase
IXO704_011945	COG5001	Diguanylate cyclase
IXO704_011970	COG0482	sulfurtransferase activity
IXO704_011985	COG0542	response to heat
IXO704_012010	COG0492	ferredoxin-NADP+ reductase activity
IXO704_012015	COG1674	ftsk spoiiie
IXO704_012040	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IXO704_012060	COG0038	chloride channel
IXO704_012065	COG0183	Belongs to the thiolase family
IXO704_012070	COG1250	3-hydroxyacyl-CoA dehydrogenase
IXO704_012070	COG1024	Enoyl-CoA hydratase
IXO704_012085	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IXO704_012095	COG1426	Protein conserved in bacteria
IXO704_012105	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IXO704_012115	COG0303	'Molybdopterin
IXO704_012170	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IXO704_012215	COG0742	ribosomal rna small subunit methyltransferase
IXO704_012220	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IXO704_012235	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IXO704_012240	COG0405	Gamma-glutamyltransferase
IXO704_012265	COG3039	Transposase
IXO704_012305	COG3039	Transposase
IXO704_012360	COG0343	queuine tRNA-ribosyltransferase activity
IXO704_012365	COG1862	Preprotein translocase
IXO704_012370	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IXO704_012375	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IXO704_012410	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IXO704_012420	COG0704	Plays a role in the regulation of phosphate uptake
IXO704_012435	COG0573	inorganic phosphate transmembrane transporter activity
IXO704_012440	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IXO704_012480	COG3039	Transposase
IXO704_012500	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IXO704_012510	COG1024	Enoyl-CoA hydratase
IXO704_012520	COG0494	nUDIX hydrolase
IXO704_012565	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IXO704_012565	COG0116	Belongs to the methyltransferase superfamily
IXO704_012590	COG0667	Aldo Keto reductase
IXO704_012600	COG2925	Exonuclease
IXO704_012630	COG0288	reversible hydration of carbon dioxide
IXO704_012665	COG0316	Belongs to the HesB IscA family
IXO704_012670	COG0360	Binds together with S18 to 16S ribosomal RNA
IXO704_012680	COG0359	binds to the 23S rRNA
IXO704_012690	COG3115	cell septum assembly
IXO704_012705	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
IXO704_012720	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IXO704_012745	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IXO704_012755	COG2986	histidine ammonia-lyase
IXO704_012760	COG1228	amidohydrolase
IXO704_012805	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IXO704_012815	COG0077	Prephenate dehydratase
IXO704_012815	COG1605	Chorismate mutase
IXO704_012820	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IXO704_012845	COG3039	Transposase
IXO704_012855	COG4566	intracellular signal transduction
IXO704_012910	COG0860	N-Acetylmuramoyl-L-alanine amidase
IXO704_012915	COG1469	GTP cyclohydrolase I activity
IXO704_012925	COG0617	tRNA 3'-terminal CCA addition
IXO704_012935	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IXO704_012940	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IXO704_012975	COG1472	Belongs to the glycosyl hydrolase 3 family
IXO704_012995	COG5001	Diguanylate cyclase
IXO704_012995	COG4251	negative regulation of phosphorylation
IXO704_012995	COG3706	GGDEF domain
IXO704_012995	COG2203	Gaf domain
IXO704_013020	COG3104	oligopeptide transport
IXO704_013085	COG0386	Belongs to the glutathione peroxidase family
IXO704_013135	COG3706	GGDEF domain
IXO704_013160	COG3039	Transposase
IXO704_013175	COG0784	Response regulator, receiver
IXO704_013175	COG2205	protein histidine kinase activity
IXO704_013175	COG5002	protein histidine kinase activity
IXO704_013210	COG0800	Aldolase
IXO704_013215	COG0129	dihydroxy-acid dehydratase activity
IXO704_013220	COG0363	glucosamine-6-phosphate deaminase activity
IXO704_013230	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IXO704_013245	COG0354	folic acid binding
IXO704_013260	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IXO704_013275	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IXO704_013290	COG4591	ABC-type transport system involved in lipoprotein release permease component
IXO704_013315	COG0811	peptide transport
IXO704_013330	COG1663	tetraacyldisaccharide 4'-kinase activity
IXO704_013340	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IXO704_013350	COG0322	excinuclease ABC activity
IXO704_013385	COG3328	transposase activity
IXO704_013425	COG2801	Transposase and inactivated derivatives
IXO704_013435	COG2201	protein-glutamate methylesterase activity
IXO704_013505	COG3039	Transposase
IXO704_013535	COG0653	protein targeting
IXO704_013575	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IXO704_013575	COG0140	phosphoribosyl-ATP diphosphatase activity
IXO704_013585	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IXO704_013595	COG0131	Imidazoleglycerol-phosphate dehydratase
IXO704_013595	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IXO704_013610	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IXO704_013630	COG0124	histidyl-tRNA synthetase
IXO704_013650	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IXO704_013685	COG1012	belongs to the aldehyde dehydrogenase family
IXO704_013705	COG0167	dihydroorotate dehydrogenase activity
IXO704_013710	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IXO704_013715	COG0697	spore germination
IXO704_013725	COG1794	racemase activity, acting on amino acids and derivatives
IXO704_013750	COG0671	phosphoesterase, PA-phosphatase related
IXO704_013765	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
IXO704_013780	COG2183	response to ionizing radiation
IXO704_013790	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IXO704_013790	COG0723	plastoquinol--plastocyanin reductase activity
IXO704_013805	COG3243	poly(R)-hydroxyalkanoic acid synthase
IXO704_013815	COG1183	phosphatidylcholine synthase activity
IXO704_013820	COG1028	Short-chain dehydrogenase reductase Sdr
IXO704_013835	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
IXO704_013845	COG0668	transmembrane transport
IXO704_013865	COG1914	H( )-stimulated, divalent metal cation uptake system
IXO704_013915	COG0583	DNA-binding transcription factor activity
IXO704_013920	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IXO704_013925	COG3002	Belongs to the UPF0753 family
IXO704_014025	COG0582	viral genome integration into host DNA
IXO704_014045	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IXO704_014065	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IXO704_014075	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IXO704_014080	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
IXO704_014090	COG0776	regulation of translation
IXO704_014095	COG0539	negative regulation of cytoplasmic translation
IXO704_014100	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IXO704_014115	COG2957	Belongs to the agmatine deiminase family
IXO704_014125	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IXO704_014150	COG0395	ABC-type sugar transport system, permease component
IXO704_014155	COG1175	transmembrane transport
IXO704_014185	COG2350	Protein conserved in bacteria
IXO704_014190	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IXO704_014195	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IXO704_014200	COG1187	pseudouridine synthase activity
IXO704_014225	COG0436	Aminotransferase
IXO704_014290	COG0277	FAD linked oxidase domain protein
IXO704_014295	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IXO704_014305	COG0531	amino acid
IXO704_014310	COG0531	amino acid
IXO704_014315	COG0235	Class ii aldolase
IXO704_014320	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
IXO704_014410	COG0583	DNA-binding transcription factor activity
IXO704_014420	COG3039	Transposase
IXO704_014515	COG0174	glutamine synthetase
IXO704_014520	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IXO704_014530	COG0477	Major facilitator Superfamily
IXO704_014540	COG0243	molybdopterin cofactor binding
IXO704_014550	COG2223	nitrite transmembrane transporter activity
IXO704_014565	COG1121	(ABC) transporter
IXO704_014575	COG2733	membrane
IXO704_014580	COG5002	protein histidine kinase activity
IXO704_014580	COG0784	Response regulator, receiver
IXO704_014580	COG2205	protein histidine kinase activity
IXO704_014590	COG3039	Transposase
IXO704_014600	COG2902	Dehydrogenase
IXO704_014610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IXO704_014615	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IXO704_014640	COG1609	Transcriptional regulator
IXO704_014645	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IXO704_014645	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IXO704_014650	COG1105	Belongs to the carbohydrate kinase PfkB family
IXO704_014655	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IXO704_014655	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IXO704_014670	COG3039	Transposase
IXO704_014705	COG3039	Transposase
IXO704_014730	COG3501	Rhs element vgr protein
IXO704_014750	COG3501	Rhs element vgr protein
IXO704_014770	COG3501	Rhs element vgr protein
IXO704_014815	COG4771	TonB-dependent receptor
IXO704_014825	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IXO704_014845	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IXO704_014850	COG1360	Flagellar Motor Protein
IXO704_014860	COG0835	chemotaxis
IXO704_014870	COG0745	RESPONSE REGULATOR receiver
IXO704_014895	COG0840	transmembrane signaling receptor activity
IXO704_014910	COG0840	transmembrane signaling receptor activity
IXO704_014920	COG0840	transmembrane signaling receptor activity
IXO704_014930	COG0840	transmembrane signaling receptor activity
IXO704_014935	COG0840	transmembrane signaling receptor activity
IXO704_014940	COG0840	transmembrane signaling receptor activity
IXO704_014945	COG0840	transmembrane signaling receptor activity
IXO704_014965	COG0835	chemotaxis
IXO704_014990	COG3039	Transposase
IXO704_015050	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IXO704_015080	COG0318	PFAM AMP-dependent synthetase and ligase
IXO704_015085	COG1024	Enoyl-CoA hydratase
IXO704_015090	COG2205	protein histidine kinase activity
IXO704_015090	COG2198	Histidine kinase
IXO704_015090	COG0784	Response regulator, receiver
IXO704_015105	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IXO704_015165	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IXO704_015175	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IXO704_015180	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IXO704_015190	COG0505	Belongs to the CarA family
IXO704_015195	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IXO704_015205	COG2258	MOSC domain
IXO704_015210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IXO704_015260	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IXO704_015280	COG0477	Major facilitator Superfamily
IXO704_015290	COG1070	Carbohydrate kinase
IXO704_015300	COG1501	Belongs to the glycosyl hydrolase 31 family
IXO704_015315	COG0800	Aldolase
IXO704_015320	COG4948	Mandelate Racemase Muconate Lactonizing
IXO704_015330	COG3734	2-keto-3-deoxy-galactonokinase
IXO704_015335	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IXO704_015345	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IXO704_015360	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IXO704_015365	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
IXO704_015375	COG0351	phosphomethylpyrimidine kinase
IXO704_015405	COG0583	DNA-binding transcription factor activity
IXO704_015410	COG1741	Belongs to the pirin family
IXO704_015430	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IXO704_015435	COG0305	Participates in initiation and elongation during chromosome replication
IXO704_015460	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IXO704_015465	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IXO704_015470	COG2137	regulation of response to DNA damage stimulus
IXO704_015475	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IXO704_015490	COG1546	Belongs to the CinA family
IXO704_015495	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IXO704_015505	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IXO704_015510	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IXO704_015520	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
IXO704_015525	COG1534	Rna-binding protein
IXO704_015540	COG1238	metal cluster binding
IXO704_015545	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IXO704_015550	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
IXO704_015555	COG2840	Smr protein MutS2
IXO704_015570	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
IXO704_015580	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
IXO704_015585	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IXO704_015590	COG0148	phosphopyruvate hydratase activity
IXO704_015600	COG2877	3-deoxy-8-phosphooctulonate synthase activity
IXO704_015605	COG0504	CTP synthase activity
IXO704_015635	COG0306	phosphate transporter
IXO704_015650	COG1253	flavin adenine dinucleotide binding
IXO704_015665	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IXO704_015685	COG0477	Major facilitator Superfamily
IXO704_015695	COG1132	(ABC) transporter
IXO704_015700	COG1136	(ABC) transporter
IXO704_015715	COG0438	transferase activity, transferring glycosyl groups
IXO704_015725	COG2264	protein methyltransferase activity
IXO704_015755	COG2244	polysaccharide biosynthetic process
IXO704_015805	COG1595	DNA-templated transcription, initiation
IXO704_015820	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IXO704_015840	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IXO704_015875	COG2201	protein-glutamate methylesterase activity
IXO704_015895	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IXO704_015955	COG1858	cytochrome C peroxidase
IXO704_015985	COG0515	serine threonine protein kinase
IXO704_015990	COG0631	protein serine/threonine phosphatase activity
IXO704_016025	COG3501	Rhs element vgr protein
IXO704_016115	COG3039	Transposase
IXO704_016190	COG2154	pterin-4-alpha-carbinolamine dehydratase
IXO704_016200	COG0428	transporter
IXO704_016205	COG0428	transporter
IXO704_016210	COG3064	Membrane
IXO704_016220	COG1530	ribonuclease E activity
IXO704_016260	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IXO704_016300	COG3039	Transposase
IXO704_016310	COG3039	Transposase
IXO704_016345	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IXO704_016345	COG1648	precorrin-2 dehydrogenase activity
IXO704_016370	COG0746	molybdenum cofactor guanylyltransferase activity
IXO704_016470	COG4206	TonB-dependent receptor
IXO704_016525	COG0531	amino acid
IXO704_016540	COG0006	proline dipeptidase activity
IXO704_016550	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IXO704_016565	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IXO704_016570	COG3938	Belongs to the proline racemase family
IXO704_016580	COG0552	protein localization to endoplasmic reticulum
IXO704_016595	COG1194	a g-specific adenine glycosylase
IXO704_016605	COG0784	Response regulator, receiver
IXO704_016605	COG4191	Histidine kinase
IXO704_016675	COG3039	Transposase
IXO704_016710	COG3040	lipid binding
IXO704_016750	COG0438	transferase activity, transferring glycosyl groups
IXO704_016760	COG0438	transferase activity, transferring glycosyl groups
IXO704_016765	COG0438	transferase activity, transferring glycosyl groups
IXO704_016820	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IXO704_016835	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IXO704_016870	COG0556	nucleotide-excision repair
IXO704_016875	COG4969	Belongs to the N-Me-Phe pilin family
IXO704_016915	COG1611	Belongs to the LOG family
IXO704_016930	COG2095	MarC family integral membrane protein
IXO704_016940	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IXO704_016975	COG1185	polyribonucleotide nucleotidyltransferase activity
IXO704_016980	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IXO704_017000	COG0195	Participates in both transcription termination and antitermination
IXO704_017005	COG0779	Required for maturation of 30S ribosomal subunits
IXO704_017015	COG1007	ATP synthesis coupled electron transport
IXO704_017045	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
IXO704_017050	COG1034	ATP synthesis coupled electron transport
IXO704_017055	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IXO704_017060	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
IXO704_017065	COG0649	NAD binding
IXO704_017070	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IXO704_017080	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IXO704_017095	COG0149	triose-phosphate isomerase activity
IXO704_017150	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IXO704_017155	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IXO704_017165	COG0159	tryptophan synthase activity
IXO704_017185	COG0135	phosphoribosylanthranilate isomerase activity
IXO704_017190	COG0101	tRNA pseudouridine synthase activity
IXO704_017210	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IXO704_017215	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IXO704_017220	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IXO704_017225	COG2890	protein-(glutamine-N5) methyltransferase activity
IXO704_017255	COG0433	COG0433 Predicted ATPase
IXO704_017260	COG2826	transposase and inactivated derivatives, IS30 family
IXO704_017280	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IXO704_017290	COG0412	Dienelactone hydrolase
IXO704_017310	COG0717	Belongs to the dCTP deaminase family
IXO704_017315	COG0489	protein tyrosine kinase activity
IXO704_017360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IXO704_017365	COG2311	Membrane
IXO704_017370	COG1047	Peptidyl-prolyl cis-trans
IXO704_017375	COG0791	NLP P60 protein
IXO704_017380	COG0791	NLP P60 protein
IXO704_017395	COG1301	dicarboxylic acid transport
IXO704_017400	COG1785	Belongs to the alkaline phosphatase family
IXO704_017405	COG0037	tRNA processing
IXO704_017410	COG1722	exodeoxyribonuclease VII activity
IXO704_017415	COG0142	geranyltranstransferase activity
IXO704_017440	COG0312	modulator of DNA gyrase
IXO704_017445	COG3028	Belongs to the UPF0307 family
IXO704_017450	COG0312	modulator of DNA gyrase
IXO704_017460	COG3164	Protein of unknown function
IXO704_017465	COG1530	ribonuclease E activity
IXO704_017475	COG2968	Membrane
IXO704_017505	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IXO704_017530	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IXO704_017560	COG3118	belongs to the thioredoxin family
IXO704_017605	COG3039	Transposase
IXO704_017655	COG3039	Transposase
IXO704_017765	COG2022	thiamine diphosphate biosynthetic process
IXO704_017775	COG3273	potassium ion transport
IXO704_017775	COG0471	metal ion transport
IXO704_017805	COG1970	mechanosensitive ion channel activity
IXO704_017825	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IXO704_017855	COG0308	aminopeptidase N
IXO704_017860	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IXO704_017875	COG2895	sulfate adenylyltransferase (ATP) activity
IXO704_017875	COG0529	Catalyzes the synthesis of activated sulfate
IXO704_017880	COG0175	sulfate reduction
IXO704_017885	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IXO704_017890	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IXO704_017895	COG0175	sulfate reduction
IXO704_017915	COG0784	Response regulator, receiver
IXO704_017915	COG2205	protein histidine kinase activity
IXO704_017915	COG2198	Histidine kinase
IXO704_017965	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
IXO704_017970	COG3588	fructose-bisphosphate aldolase
IXO704_017975	COG0469	pyruvate kinase activity
IXO704_018020	COG0753	catalase activity
IXO704_018050	COG2207	Transcriptional regulator
IXO704_018050	COG1917	Cupin 2, conserved barrel domain protein
IXO704_018070	COG0823	Involved in the tonB-independent uptake of proteins
IXO704_018070	COG1506	peptidase
IXO704_018095	COG1297	OPT oligopeptide transporter protein
IXO704_018115	COG0587	DNA-directed DNA polymerase activity
IXO704_018200	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
IXO704_018205	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
IXO704_018210	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
IXO704_018215	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
IXO704_018235	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
IXO704_018290	COG3501	Rhs element vgr protein
IXO704_018300	COG3039	Transposase
IXO704_018360	COG3501	Rhs element vgr protein
IXO704_018425	COG3501	Rhs element vgr protein
IXO704_018430	COG3179	chitinase
IXO704_018440	COG3501	Rhs element vgr protein
IXO704_018455	COG3039	Transposase
IXO704_018475	COG3501	Rhs element vgr protein
IXO704_018550	COG3501	Rhs element vgr protein
IXO704_018555	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IXO704_018565	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IXO704_018575	COG3501	Rhs element vgr protein
IXO704_018655	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IXO704_018670	COG2197	response regulator
IXO704_018675	COG4585	Histidine kinase
IXO704_018695	COG2894	cell division
IXO704_018700	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
IXO704_018710	COG0642	Histidine kinase
IXO704_018715	COG0745	RESPONSE REGULATOR receiver
IXO704_018720	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IXO704_018730	COG2194	sulfuric ester hydrolase activity
IXO704_018760	COG3551	Protein conserved in bacteria
IXO704_018825	COG0203	ribosomal protein L17
IXO704_018835	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IXO704_018840	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IXO704_018850	COG0201	protein transport
IXO704_018860	COG1841	ribosomal large subunit assembly
IXO704_018870	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IXO704_018890	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IXO704_018900	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IXO704_018905	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IXO704_018910	COG0255	Belongs to the universal ribosomal protein uL29 family
IXO704_018915	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IXO704_018925	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IXO704_018940	COG0089	rRNA binding
IXO704_018945	COG0088	Forms part of the polypeptide exit tunnel
IXO704_018950	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IXO704_018955	COG0051	transcription antitermination factor activity, RNA binding
IXO704_018975	COG0049	tRNA binding
IXO704_018980	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IXO704_018985	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IXO704_018990	COG0085	RNA polymerase activity
IXO704_018995	COG0222	ribosome binding
IXO704_019000	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IXO704_019010	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IXO704_019020	COG0250	Participates in transcription elongation, termination and antitermination
IXO704_019025	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IXO704_019055	COG0012	GTP binding
IXO704_019060	COG0193	aminoacyl-tRNA hydrolase activity
IXO704_019070	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IXO704_019085	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
IXO704_019095	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IXO704_019100	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IXO704_019115	COG0521	Mo-molybdopterin cofactor biosynthetic process
IXO704_019135	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IXO704_019140	COG1295	ribonuclease BN
IXO704_019170	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IXO704_019175	COG1404	Belongs to the peptidase S8 family
IXO704_019190	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IXO704_019220	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
IXO704_019245	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
IXO704_019260	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IXO704_019260	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IXO704_019310	COG2890	protein-(glutamine-N5) methyltransferase activity
IXO704_019320	COG3634	alkyl hydroperoxide reductase activity
IXO704_019325	COG0583	DNA-binding transcription factor activity
IXO704_019340	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IXO704_019370	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IXO704_019410	COG0584	glycerophosphoryl diester phosphodiesterase
IXO704_019435	COG3039	Transposase
IXO704_019455	COG0625	glutathione transferase activity
IXO704_019460	COG0039	L-malate dehydrogenase activity
IXO704_019465	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IXO704_019490	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
IXO704_019640	COG3781	membrane
IXO704_019650	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IXO704_019680	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
IXO704_019700	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IXO704_019725	COG3710	Transcriptional regulator
IXO704_019730	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IXO704_019740	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IXO704_019770	COG2226	methyltransferase
IXO704_019775	COG0066	3-isopropylmalate dehydratase activity
IXO704_019780	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IXO704_019810	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IXO704_019815	COG1538	Outer membrane efflux protein
IXO704_019820	COG1519	Transferase
IXO704_019825	COG1560	Kdo2-lipid A biosynthetic process
IXO704_019885	COG0308	aminopeptidase N
IXO704_019890	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IXO704_019900	COG0330	HflC and HflK could
IXO704_019905	COG0330	HflC and HflK could
IXO704_019925	COG0678	peroxiredoxin activity
IXO704_019935	COG2826	transposase and inactivated derivatives, IS30 family
IXO704_019970	COG3039	Transposase
IXO704_020005	COG3829	transcription factor binding
IXO704_020040	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IXO704_020045	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IXO704_020055	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IXO704_020060	COG1028	Short-chain dehydrogenase reductase Sdr
IXO704_020085	COG1399	metal-binding, possibly nucleic acid-binding protein
IXO704_020110	COG3039	Transposase
IXO704_020155	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IXO704_020205	COG3039	Transposase
IXO704_020215	COG2188	Transcriptional regulator
IXO704_020235	COG1450	Type ii and iii secretion system protein
IXO704_020250	COG3166	PFAM Fimbrial assembly family protein
IXO704_020255	COG3156	type II secretion system protein K
IXO704_020260	COG4795	General secretion pathway protein
IXO704_020265	COG2165	general secretion pathway protein
IXO704_020270	COG4970	Tfp pilus assembly protein FimT
IXO704_020275	COG2165	general secretion pathway protein
IXO704_020280	COG1459	type II secretion system
IXO704_020290	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IXO704_020300	COG5295	Hep Hag repeat protein
IXO704_020310	COG0047	phosphoribosylformylglycinamidine synthase activity
IXO704_020310	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IXO704_020315	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IXO704_020320	COG4974	Belongs to the 'phage' integrase family
IXO704_020335	COG0795	lipopolysaccharide-transporting ATPase activity
IXO704_020345	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IXO704_020360	COG0525	valine-tRNA ligase activity
IXO704_020395	COG3039	Transposase
IXO704_020440	COG3039	Transposase
IXO704_020475	COG1183	phosphatidylcholine synthase activity
IXO704_020485	COG0442	prolyl-tRNA aminoacylation
IXO704_020500	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IXO704_020505	COG1127	ABC transporter
IXO704_020510	COG3218	ABC-type transport auxiliary lipoprotein component
IXO704_020510	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IXO704_020550	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IXO704_020555	COG0662	Cupin 2, conserved barrel domain protein
IXO704_020555	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
IXO704_020580	COG2086	electron transfer activity
IXO704_020605	COG3328	transposase activity
IXO704_020655	COG0626	cystathionine gamma-synthase activity
IXO704_020685	COG0625	glutathione transferase activity
IXO704_020700	COG0513	Belongs to the DEAD box helicase family
IXO704_020710	COG0720	synthase
IXO704_020720	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IXO704_020725	COG1956	GAF domain-containing protein
IXO704_020765	COG0339	signal peptide processing
IXO704_020815	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IXO704_020820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IXO704_020870	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IXO704_020875	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IXO704_020880	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IXO704_020885	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IXO704_020895	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IXO704_020905	COG0356	it plays a direct role in the translocation of protons across the membrane
IXO704_020925	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IXO704_020935	COG0508	dehydrogenase complex catalyzes the overall conversion of
IXO704_020965	COG2011	ABC-type metal ion transport system permease component
IXO704_020975	COG0697	spore germination
IXO704_021010	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IXO704_021015	COG1187	pseudouridine synthase activity
IXO704_021020	COG2813	Specifically methylates the guanine in position
IXO704_021050	COG2205	protein histidine kinase activity
IXO704_021050	COG2202	Pas domain
IXO704_021075	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IXO704_021125	COG0745	RESPONSE REGULATOR receiver
IXO704_021140	COG1404	Belongs to the peptidase S8 family
IXO704_021155	COG0842	Transport permease protein
IXO704_021160	COG1131	(ABC) transporter
IXO704_021165	COG0025	NhaP-type Na H and K H
IXO704_021175	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
IXO704_021185	COG1573	uracil-dna glycosylase
IXO704_021195	COG3384	dioxygenase
IXO704_021210	COG0667	Aldo Keto reductase
IXO704_021225	COG3590	peptidase
IXO704_021245	COG0531	amino acid
IXO704_021270	COG2972	Histidine kinase
IXO704_021335	COG1271	oxidase subunit
IXO704_021500	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IXO704_021510	COG1560	Kdo2-lipid A biosynthetic process
IXO704_021560	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IXO704_021560	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IXO704_021565	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IXO704_021570	COG0242	peptide deformylase activity
IXO704_021575	COG1652	LysM domain
IXO704_021580	COG0758	DNA mediated transformation
IXO704_021585	COG2922	Belongs to the Smg family
IXO704_021600	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IXO704_021600	COG1754	DNA topoisomerase type I activity
IXO704_021605	COG0009	L-threonylcarbamoyladenylate synthase
IXO704_021620	COG1028	Short-chain dehydrogenase reductase Sdr
IXO704_021630	COG0616	signal peptide processing
IXO704_021635	COG0534	Mate efflux family protein
IXO704_021660	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IXO704_021695	COG1324	tolerance protein
IXO704_021715	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
IXO704_021720	COG0511	ligase activity, forming carbon-carbon bonds
IXO704_021730	COG0439	Biotin carboxylase
IXO704_021785	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
IXO704_021860	COG3039	Transposase
IXO704_021890	COG3039	Transposase
IXO704_021985	COG3210	domain, Protein
IXO704_021990	COG2831	hemolysin activation secretion protein
IXO704_022020	COG2267	carboxylic ester hydrolase activity
IXO704_022030	COG2267	carboxylic ester hydrolase activity
IXO704_022040	COG0138	bifunctional purine biosynthesis protein purh
IXO704_022050	COG0151	Belongs to the GarS family
IXO704_022075	COG1289	transmembrane transporter activity
IXO704_022090	COG2814	Major facilitator Superfamily
IXO704_022115	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
IXO704_022150	COG0745	RESPONSE REGULATOR receiver
IXO704_022200	COG0739	heme binding
IXO704_022215	COG2211	Major facilitator Superfamily
IXO704_022220	COG0708	Exodeoxyribonuclease III
IXO704_022235	COG1192	Involved in chromosome partitioning
IXO704_022240	COG1475	DNA binding
IXO704_022260	COG0463	Glycosyl transferase, family 2
IXO704_022285	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IXO704_022295	COG0018	arginyl-trna synthetase
IXO704_022310	COG4221	oxidoreductase activity
IXO704_022335	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IXO704_022340	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IXO704_022355	COG3485	protocatechuate 3,4-dioxygenase
IXO704_022360	COG3485	protocatechuate 3,4-dioxygenase
IXO704_022395	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IXO704_022405	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IXO704_022420	COG1042	CoA-binding domain protein
IXO704_022420	COG0045	succinate-CoA ligase (ADP-forming) activity
IXO704_022420	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IXO704_022435	COG2239	Acts as a magnesium transporter
IXO704_022455	COG3039	Transposase
IXO704_022470	COG3328	transposase activity
IXO704_022485	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IXO704_022485	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IXO704_022495	COG1473	amidohydrolase
IXO704_022500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IXO704_022505	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IXO704_022520	COG5383	Protein conserved in bacteria
IXO704_022555	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IXO704_022560	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
IXO704_022575	COG0028	Belongs to the TPP enzyme family
IXO704_022580	COG4191	Histidine kinase
IXO704_022605	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IXO704_022620	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IXO704_022625	COG3177	Filamentation induced by cAMP protein fic
IXO704_022640	COG0596	Alpha beta hydrolase
IXO704_022645	COG0727	PFAM Uncharacterised protein family (UPF0153)
IXO704_022650	COG0318	PFAM AMP-dependent synthetase and ligase
IXO704_022655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IXO704_022715	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IXO704_022725	COG0129	dihydroxy-acid dehydratase activity
IXO704_022750	COG3039	Transposase
IXO704_022760	COG0408	coproporphyrinogen oxidase activity
IXO704_022810	COG0232	Belongs to the dGTPase family. Type 2 subfamily
IXO704_022830	COG2201	protein-glutamate methylesterase activity
IXO704_022870	COG2353	YceI-like domain
IXO704_022900	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IXO704_022915	COG3386	PFAM SMP-30 Gluconolaconase
IXO704_022955	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IXO704_022970	COG4771	TonB-dependent receptor
IXO704_022980	COG0459	protein refolding
IXO704_023005	COG1252	NADH dehydrogenase
IXO704_023015	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IXO704_023020	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IXO704_023025	COG3437	response regulator, receiver
IXO704_023030	COG2177	Part of the ABC transporter FtsEX involved in
IXO704_023035	COG2884	Cell division ATP-binding protein ftsE
IXO704_023045	COG3118	belongs to the thioredoxin family
IXO704_023050	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IXO704_023065	COG0729	surface antigen
IXO704_023070	COG2911	Protein conserved in bacteria
IXO704_023105	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IXO704_023120	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IXO704_023180	COG1733	regulation of RNA biosynthetic process
IXO704_023185	COG0702	epimerase
IXO704_023215	COG0583	DNA-binding transcription factor activity
IXO704_023220	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IXO704_023240	COG0745	RESPONSE REGULATOR receiver
IXO704_023270	COG1902	pentaerythritol trinitrate reductase activity
IXO704_023275	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IXO704_023285	COG2814	Major facilitator Superfamily
IXO704_023290	COG0583	DNA-binding transcription factor activity
IXO704_023305	COG0084	hydrolase, TatD family'
IXO704_023350	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IXO704_023370	COG2072	flavoprotein involved in K transport
IXO704_023435	COG4770	biotin carboxylase activity
IXO704_023440	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IXO704_023445	COG1960	acyl-CoA dehydrogenase activity
IXO704_023500	COG0523	cobalamin synthesis protein
IXO704_023510	COG0697	spore germination
IXO704_023520	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IXO704_023535	COG4771	TonB-dependent receptor
IXO704_023540	COG0457	Tetratricopeptide repeat
IXO704_023550	COG0752	glycyl-tRNA synthetase alpha subunit
IXO704_023555	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IXO704_023580	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IXO704_023580	COG0519	Catalyzes the synthesis of GMP from XMP
IXO704_023590	COG0805	protein transport
IXO704_023600	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IXO704_023610	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
IXO704_023635	COG2974	May be involved in recombination
IXO704_023640	COG0037	tRNA processing
IXO704_023660	COG3661	Belongs to the glycosyl hydrolase 67 family
IXO704_023670	COG4948	Mandelate Racemase Muconate Lactonizing
IXO704_023680	COG1472	Belongs to the glycosyl hydrolase 3 family
IXO704_023685	COG0246	Mannitol dehydrogenase
IXO704_023710	COG3693	PFAM glycoside hydrolase, family 10
IXO704_023735	COG2211	Major facilitator Superfamily
IXO704_023785	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IXO704_023825	COG1846	Transcriptional regulator
IXO704_023830	COG1764	response to oxidative stress
IXO704_023920	COG3549	Plasmid maintenance system killer
IXO704_023930	COG1074	ATP-dependent DNA helicase activity
IXO704_023935	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IXO704_023980	COG2032	superoxide dismutase activity
IXO704_023985	COG2032	superoxide dismutase activity
IXO704_023990	COG2204	response regulator
IXO704_023995	COG3852	Histidine kinase
IXO704_024000	COG0004	ammonium transporteR
IXO704_024005	COG0347	Belongs to the P(II) protein family
IXO704_024010	COG0174	glutamine synthetase
IXO704_024015	COG1968	undecaprenyl-diphosphatase activity
IXO704_024060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IXO704_024070	COG2062	phosphohistidine phosphatase, SixA
IXO704_024075	COG0489	protein tyrosine kinase activity
IXO704_024095	COG1396	sequence-specific DNA binding
IXO704_024100	COG3550	peptidyl-serine autophosphorylation
IXO704_024105	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
IXO704_024110	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IXO704_024125	COG1125	glycine betaine transport
IXO704_024125	COG0517	IMP dehydrogenase activity
IXO704_024140	COG1119	ATPase activity
IXO704_024150	COG1752	Esterase of the alpha-beta hydrolase superfamily
IXO704_024165	COG3039	Transposase
IXO704_024190	COG0656	L-ascorbic acid biosynthetic process
IXO704_024195	COG2130	NADP-dependent
IXO704_024200	COG0667	Aldo Keto reductase
IXO704_024210	COG1187	pseudouridine synthase activity
IXO704_024225	COG1643	Atp-dependent helicase
IXO704_024230	COG4807	Protein conserved in bacteria
IXO704_024235	COG4948	Mandelate Racemase Muconate Lactonizing
IXO704_024245	COG0179	Fumarylacetoacetate (FAA) hydrolase
IXO704_024250	COG1028	Short-chain dehydrogenase reductase Sdr
IXO704_024270	COG3507	Belongs to the glycosyl hydrolase 43 family
IXO704_024310	COG3162	membrane
IXO704_024315	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IXO704_024335	COG0708	Exodeoxyribonuclease III
IXO704_024350	COG2091	lysine biosynthetic process via aminoadipic acid
IXO704_024360	COG3540	Alkaline phosphatase
IXO704_024365	COG0357	Ribosomal RNA small subunit methyltransferase G
IXO704_024390	COG2159	amidohydrolase
IXO704_024405	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IXO704_024410	COG0583	DNA-binding transcription factor activity
IXO704_024415	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IXO704_024435	COG0210	DNA helicase
IXO704_024455	COG0531	amino acid
IXO704_024465	COG1322	Protein conserved in bacteria
IXO704_024475	COG0386	Belongs to the glutathione peroxidase family
IXO704_024535	COG0793	Belongs to the peptidase S41A family
IXO704_024540	COG4942	peptidase
IXO704_024550	COG2234	aminopeptidase activity
IXO704_024600	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IXO704_024605	COG0302	gtp cyclohydrolase
IXO704_024625	COG0477	Major facilitator Superfamily
IXO704_024750	COG3039	Transposase
IXO704_024760	COG1929	Belongs to the glycerate kinase type-1 family
IXO704_024765	COG2271	Major facilitator Superfamily
IXO704_024780	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IXO704_024790	COG0861	Integral membrane protein TerC family
IXO704_024805	COG0584	glycerophosphoryl diester phosphodiesterase
IXO704_024815	COG0671	phosphoesterase, PA-phosphatase related
IXO704_024825	COG0726	polysaccharide deacetylase
IXO704_024830	COG0706	membrane insertase activity