locus-tag	class	description
IXO842_000005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IXO842_000020	COG0187	DNA topoisomerase II activity
IXO842_000030	COG0501	Belongs to the peptidase M48B family
IXO842_000060	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IXO842_000070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IXO842_000080	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
IXO842_000090	COG4772	TonB-dependent receptor
IXO842_000110	COG1304	FMN binding
IXO842_000140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IXO842_000220	COG2826	transposase and inactivated derivatives, IS30 family
IXO842_000245	COG3039	Transposase
IXO842_000255	COG1090	epimerase
IXO842_000265	COG0642	Histidine kinase
IXO842_000275	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IXO842_000380	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IXO842_000455	COG3264	Mechanosensitive ion channel
IXO842_000455	COG1511	domain protein
IXO842_000470	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IXO842_000475	COG2354	Protein conserved in bacteria
IXO842_000480	COG1649	PFAM Uncharacterised BCR, COG1649
IXO842_000500	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IXO842_000525	COG0702	epimerase
IXO842_000540	COG1858	cytochrome C peroxidase
IXO842_000615	COG0513	Belongs to the DEAD box helicase family
IXO842_000620	COG3039	Transposase
IXO842_000665	COG1136	(ABC) transporter
IXO842_000690	COG1136	(ABC) transporter
IXO842_000735	COG1272	protein, Hemolysin III
IXO842_000740	COG1111	helicase
IXO842_000740	COG1205	dead DEAH box helicase
IXO842_000800	COG0069	glutamate synthase activity
IXO842_000800	COG0070	glutamate synthase
IXO842_000800	COG0067	glutamate synthase
IXO842_000805	COG0493	'glutamate synthase
IXO842_000845	COG1609	Transcriptional regulator
IXO842_000875	COG0366	Alpha amylase catalytic
IXO842_000880	COG0366	Alpha amylase catalytic
IXO842_000920	COG0606	chelatase, subunit chli
IXO842_000960	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IXO842_000965	COG1166	arginine decarboxylase activity
IXO842_001045	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IXO842_001070	COG1028	Short-chain dehydrogenase reductase Sdr
IXO842_001095	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
IXO842_001110	COG0210	DNA helicase
IXO842_001125	COG3132	Protein of unknown function, DUF480
IXO842_001130	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
IXO842_001135	COG0284	orotidine-5'-phosphate decarboxylase activity
IXO842_001175	COG3321	synthase
IXO842_001175	COG0604	alcohol dehydrogenase
IXO842_001175	COG1028	Short-chain dehydrogenase reductase Sdr
IXO842_001200	COG2755	lipolytic protein G-D-S-L family
IXO842_001215	COG3186	Phenylalanine-4-hydroxylase
IXO842_001220	COG1522	sequence-specific DNA binding
IXO842_001265	COG1064	alcohol dehydrogenase
IXO842_001270	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IXO842_001275	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IXO842_001285	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IXO842_001305	COG0676	glucose-6-phosphate 1-epimerase activity
IXO842_001370	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IXO842_001390	COG2853	Lipoprotein
IXO842_001405	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IXO842_001410	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IXO842_001415	COG1127	ABC transporter
IXO842_001490	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IXO842_001495	COG3265	gluconokinase activity
IXO842_001500	COG2211	Major facilitator Superfamily
IXO842_001505	COG3459	Glycosyltransferase 36 associated
IXO842_001515	COG2205	protein histidine kinase activity
IXO842_001525	COG1414	Transcriptional regulator
IXO842_001530	COG0738	Major facilitator superfamily
IXO842_001535	COG3254	rhamnose metabolic process
IXO842_001565	COG0339	signal peptide processing
IXO842_001595	COG0564	pseudouridine synthase activity
IXO842_001605	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IXO842_001615	COG1181	Belongs to the D-alanine--D-alanine ligase family
IXO842_001655	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IXO842_001665	COG0842	Transport permease protein
IXO842_001670	COG1131	(ABC) transporter
IXO842_001700	COG1476	TRANSCRIPTIONal
IXO842_001710	COG4555	ABC transporter
IXO842_001745	COG0625	glutathione transferase activity
IXO842_001790	COG0583	DNA-binding transcription factor activity
IXO842_001830	COG1199	ATP-dependent helicase activity
IXO842_001850	COG1566	PFAM secretion protein HlyD family protein
IXO842_001870	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IXO842_001910	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
IXO842_001910	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
IXO842_001915	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IXO842_001930	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IXO842_001965	COG3237	CsbD-like
IXO842_001970	COG0180	Tryptophanyl-tRNA synthetase
IXO842_001975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IXO842_002020	COG0753	catalase activity
IXO842_002025	COG1595	DNA-templated transcription, initiation
IXO842_002035	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IXO842_002045	COG0628	permease
IXO842_002055	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IXO842_002060	COG1040	competence protein
IXO842_002065	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IXO842_002070	COG0156	8-amino-7-oxononanoate synthase activity
IXO842_002080	COG1028	Short-chain dehydrogenase reductase Sdr
IXO842_002095	COG0463	Glycosyl transferase, family 2
IXO842_002105	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IXO842_002110	COG3100	YcgL domain-containing protein
IXO842_002130	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IXO842_002135	COG3039	Transposase
IXO842_002195	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IXO842_002210	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IXO842_002215	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
IXO842_002225	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
IXO842_002230	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IXO842_002235	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IXO842_002285	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IXO842_002300	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
IXO842_002365	COG0358	DNA primase activity
IXO842_002370	COG1295	ribonuclease BN
IXO842_002380	COG1610	YqeY-like protein
IXO842_002390	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IXO842_002395	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IXO842_002435	COG2133	pyrroloquinoline quinone binding
IXO842_002440	COG4682	membrane
IXO842_002465	COG0531	amino acid
IXO842_002490	COG4948	Mandelate Racemase Muconate Lactonizing
IXO842_002500	COG3023	N-Acetylmuramoyl-L-alanine amidase
IXO842_002505	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
IXO842_002575	COG0183	Belongs to the thiolase family
IXO842_002615	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IXO842_002625	COG3483	tryptophan 2,3-dioxygenase activity
IXO842_002630	COG3104	oligopeptide transport
IXO842_002660	COG1320	monovalent cation:proton antiporter activity
IXO842_002665	COG2212	antiporter activity
IXO842_002675	COG0651	ATP synthesis coupled electron transport
IXO842_002680	COG1006	Multisubunit Na H antiporter MnhC subunit
IXO842_002685	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IXO842_002685	COG2111	Na H antiporter
IXO842_002735	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IXO842_002745	COG0456	acetyltransferase
IXO842_002765	COG2801	Transposase and inactivated derivatives
IXO842_002775	COG4221	oxidoreductase activity
IXO842_002815	COG3039	Transposase
IXO842_002835	COG0697	spore germination
IXO842_002840	COG4305	rare lipoprotein A
IXO842_002845	COG5297	Belongs to the glycosyl hydrolase family 6
IXO842_002850	COG1113	amino acid transport
IXO842_002860	COG0598	Magnesium transport protein CorA
IXO842_002930	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IXO842_002930	COG5297	Belongs to the glycosyl hydrolase family 6
IXO842_002935	COG0659	secondary active sulfate transmembrane transporter activity
IXO842_002970	COG3275	phosphorelay sensor kinase activity
IXO842_002980	COG0181	hydroxymethylbilane synthase activity
IXO842_003005	COG1505	serine-type exopeptidase activity
IXO842_003020	COG3039	Transposase
IXO842_003025	COG0436	Aminotransferase
IXO842_003055	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IXO842_003085	COG0308	aminopeptidase N
IXO842_003090	COG2199	diguanylate cyclase activity
IXO842_003140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IXO842_003145	COG1077	Cell shape determining protein MreB Mrl
IXO842_003150	COG1792	Involved in formation and maintenance of cell shape
IXO842_003165	COG0772	Belongs to the SEDS family
IXO842_003200	COG2951	lytic endotransglycosylase activity
IXO842_003205	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IXO842_003210	COG1686	Belongs to the peptidase S11 family
IXO842_003220	COG2921	Belongs to the UPF0250 family
IXO842_003245	COG1051	belongs to the nudix hydrolase family
IXO842_003245	COG1056	cytidyltransferase-related domain
IXO842_003280	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
IXO842_003285	COG0673	inositol 2-dehydrogenase activity
IXO842_003290	COG2823	Periplasmic or secreted lipoprotein
IXO842_003295	COG4251	negative regulation of phosphorylation
IXO842_003300	COG0784	Response regulator, receiver
IXO842_003305	COG4191	Histidine kinase
IXO842_003310	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IXO842_003360	COG3250	beta-galactosidase activity
IXO842_003375	COG2188	Transcriptional regulator
IXO842_003385	COG1609	Transcriptional regulator
IXO842_003390	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IXO842_003395	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IXO842_003405	COG1215	transferase activity, transferring glycosyl groups
IXO842_003410	COG0726	polysaccharide deacetylase
IXO842_003410	COG1649	PFAM Uncharacterised BCR, COG1649
IXO842_003490	COG3039	Transposase
IXO842_003495	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IXO842_003500	COG3039	Transposase
IXO842_003535	COG0218	Necessary for normal cell division and for the maintenance of normal septation
IXO842_003550	COG2205	protein histidine kinase activity
IXO842_003585	COG2205	protein histidine kinase activity
IXO842_003625	COG3039	Transposase
IXO842_003640	COG0488	(ABC) transporter
IXO842_003660	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IXO842_003680	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IXO842_003680	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IXO842_003700	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
IXO842_003705	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IXO842_003710	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IXO842_003730	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IXO842_003735	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
IXO842_003745	COG2205	protein histidine kinase activity
IXO842_003750	COG0745	RESPONSE REGULATOR receiver
IXO842_003755	COG0277	FAD linked oxidase domain protein
IXO842_003760	COG1988	membrane-bound metal-dependent
IXO842_003765	COG0792	nuclease activity
IXO842_003800	COG0275	rRNA processing
IXO842_003805	COG3116	cell division
IXO842_003820	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IXO842_003825	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IXO842_003840	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IXO842_003845	COG1181	Belongs to the D-alanine--D-alanine ligase family
IXO842_003850	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IXO842_003865	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
IXO842_003875	COG4942	peptidase
IXO842_003875	COG1388	LysM domain
IXO842_003880	COG0653	protein targeting
IXO842_003890	COG0494	nUDIX hydrolase
IXO842_003905	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IXO842_003915	COG0604	alcohol dehydrogenase
IXO842_003915	COG1028	Short-chain dehydrogenase reductase Sdr
IXO842_003915	COG3321	synthase
IXO842_003970	COG2226	methyltransferase
IXO842_003975	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IXO842_004010	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IXO842_004015	COG3039	Transposase
IXO842_004030	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IXO842_004040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IXO842_004045	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IXO842_004055	COG3039	Transposase
IXO842_004075	COG0667	Aldo Keto reductase
IXO842_004130	COG2175	clavaminate synthase activity
IXO842_004140	COG4181	ATPase activity
IXO842_004155	COG0642	Histidine kinase
IXO842_004175	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IXO842_004195	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IXO842_004220	COG2967	ApaG domain
IXO842_004225	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IXO842_004235	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IXO842_004250	COG0123	including yeast histone deacetylase and acetoin utilization protein
IXO842_004255	COG2096	Adenosyltransferase
IXO842_004265	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IXO842_004270	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IXO842_004310	COG0583	DNA-binding transcription factor activity
IXO842_004315	COG0318	PFAM AMP-dependent synthetase and ligase
IXO842_004325	COG1024	Enoyl-CoA hydratase
IXO842_004345	COG3386	PFAM SMP-30 Gluconolaconase
IXO842_004460	COG0446	pyridine nucleotide-disulphide oxidoreductase
IXO842_004460	COG1902	pentaerythritol trinitrate reductase activity
IXO842_004465	COG0604	alcohol dehydrogenase
IXO842_004490	COG0156	8-amino-7-oxononanoate synthase activity
IXO842_004495	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IXO842_004500	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IXO842_004505	COG4208	sulfate ABC transporter
IXO842_004510	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IXO842_004540	COG0588	phosphoglycerate mutase activity
IXO842_004550	COG0285	dihydrofolate synthase activity
IXO842_004570	COG2833	Protein of unknown function (DUF455)
IXO842_004590	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IXO842_004595	COG0671	phosphoesterase, PA-phosphatase related
IXO842_004600	COG0438	transferase activity, transferring glycosyl groups
IXO842_004610	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IXO842_004625	COG4783	chaperone-mediated protein folding
IXO842_004650	COG0473	3-isopropylmalate dehydrogenase activity
IXO842_004700	COG0544	peptidyl-prolyl cis-trans isomerase activity
IXO842_004740	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IXO842_004765	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IXO842_004775	COG0631	protein serine/threonine phosphatase activity
IXO842_004845	COG0582	viral genome integration into host DNA
IXO842_004855	COG0859	PFAM glycosyl transferase family 9
IXO842_004860	COG3642	lipopolysaccharide core region biosynthetic process
IXO842_004865	COG1234	tRNA 3'-trailer cleavage
IXO842_004870	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IXO842_004880	COG0315	cyclic pyranopterin monophosphate synthase activity
IXO842_004885	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IXO842_004890	COG0314	molybdopterin synthase activity
IXO842_004920	COG0537	adenosine 5'-monophosphoramidase activity
IXO842_004940	COG0714	Associated with various cellular activities
IXO842_004960	COG0242	peptide deformylase activity
IXO842_005040	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IXO842_005070	COG1162	GTPase activity
IXO842_005095	COG2211	Major facilitator Superfamily
IXO842_005105	COG1609	Transcriptional regulator
IXO842_005110	COG1028	Short-chain dehydrogenase reductase Sdr
IXO842_005115	COG2851	Citrate transporter
IXO842_005140	COG2197	response regulator
IXO842_005155	COG0583	DNA-binding transcription factor activity
IXO842_005170	COG4191	Histidine kinase
IXO842_005190	COG0280	phosphate acetyltransferase
IXO842_005190	COG0281	malic enzyme
IXO842_005260	COG0352	thiamine-phosphate diphosphorylase activity
IXO842_005265	COG1773	rubredoxin
IXO842_005270	COG2912	Transglutaminase-like superfamily
IXO842_005280	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IXO842_005290	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IXO842_005315	COG0006	proline dipeptidase activity
IXO842_005345	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IXO842_005360	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IXO842_005365	COG1561	YicC-like family, N-terminal region
IXO842_005390	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IXO842_005400	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IXO842_005425	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
IXO842_005470	COG0714	Associated with various cellular activities
IXO842_005490	COG2304	oxidoreductase activity
IXO842_005510	COG1301	dicarboxylic acid transport
IXO842_005515	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IXO842_005525	COG0739	heme binding
IXO842_005530	COG1376	ErfK ybiS ycfS ynhG family protein
IXO842_005555	COG1022	Amp-dependent synthetase and ligase
IXO842_005565	COG1028	Short-chain dehydrogenase reductase Sdr
IXO842_005580	COG0642	Histidine kinase
IXO842_005600	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IXO842_005605	COG4149	molybdate abc transporter
IXO842_005610	COG0725	ABC transporter, periplasmic molybdate-binding protein
IXO842_005615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IXO842_005615	COG3453	Protein conserved in bacteria
IXO842_005655	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IXO842_005675	COG2205	protein histidine kinase activity
IXO842_005680	COG0745	RESPONSE REGULATOR receiver
IXO842_005730	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IXO842_005735	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IXO842_005780	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IXO842_005800	COG2801	Transposase and inactivated derivatives
IXO842_005840	COG2201	protein-glutamate methylesterase activity
IXO842_005870	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IXO842_005880	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IXO842_005885	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IXO842_005900	COG1842	Phage shock protein A
IXO842_005925	COG0754	glutathionylspermidine amidase activity
IXO842_005990	COG0531	amino acid
IXO842_005995	COG2197	response regulator
IXO842_006010	COG1113	amino acid transport
IXO842_006030	COG1271	oxidase subunit
IXO842_006035	COG1294	oxidase, subunit
IXO842_006045	COG2239	Acts as a magnesium transporter
IXO842_006050	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IXO842_006055	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IXO842_006070	COG1660	Displays ATPase and GTPase activities
IXO842_006075	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IXO842_006080	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IXO842_006095	COG1137	ATPase activity
IXO842_006100	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IXO842_006110	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IXO842_006120	COG0271	Belongs to the BolA IbaG family
IXO842_006130	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IXO842_006150	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IXO842_006165	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IXO842_006175	COG0628	permease
IXO842_006185	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IXO842_006190	COG3178	'Phosphotransferase
IXO842_006205	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IXO842_006210	COG1555	photosystem II stabilization
IXO842_006260	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IXO842_006270	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IXO842_006295	COG0228	four-way junction DNA binding
IXO842_006300	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IXO842_006305	COG0336	Belongs to the RNA methyltransferase TrmD family
IXO842_006320	COG0534	Mate efflux family protein
IXO842_006355	COG0542	response to heat
IXO842_006390	COG4206	TonB-dependent receptor
IXO842_006450	COG0019	diaminopimelate decarboxylase activity
IXO842_006460	COG2814	Major facilitator Superfamily
IXO842_006465	COG4264	IucA IucC family
IXO842_006475	COG4772	TonB-dependent receptor
IXO842_006490	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IXO842_006490	COG4651	solute:proton antiporter activity
IXO842_006530	COG0488	(ABC) transporter
IXO842_006555	COG2755	lipolytic protein G-D-S-L family
IXO842_006555	COG0657	acetylesterase activity
IXO842_006595	COG2207	Transcriptional regulator
IXO842_006600	COG0326	Molecular chaperone. Has ATPase activity
IXO842_006625	COG3328	transposase activity
IXO842_006630	COG0174	glutamine synthetase
IXO842_006635	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
IXO842_006645	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IXO842_006660	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IXO842_006685	COG2146	nitrite reductase [NAD(P)H] activity
IXO842_006695	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IXO842_006700	COG0719	Fe-S assembly protein
IXO842_006705	COG0396	ATPase activity
IXO842_006710	COG0719	Fe-S assembly protein
IXO842_006715	COG1959	2 iron, 2 sulfur cluster binding
IXO842_006735	COG0693	protein deglycase activity
IXO842_006775	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IXO842_006805	COG0519	Catalyzes the synthesis of GMP from XMP
IXO842_006815	COG1678	Uncharacterized ACR, COG1678
IXO842_006820	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IXO842_006850	COG1764	response to oxidative stress
IXO842_006860	COG0384	phenazine biosynthesis protein PhzF
IXO842_006870	COG0527	aspartate kinase activity
IXO842_006895	COG0142	geranyltranstransferase activity
IXO842_006900	COG0629	single-stranded DNA binding
IXO842_006905	COG3706	GGDEF domain
IXO842_006905	COG5001	Diguanylate cyclase
IXO842_006905	COG4251	negative regulation of phosphorylation
IXO842_006905	COG2203	Gaf domain
IXO842_006935	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IXO842_006980	COG2879	small protein
IXO842_006985	COG1966	Carbon starvation protein
IXO842_006990	COG1741	Belongs to the pirin family
IXO842_007035	COG1741	Belongs to the pirin family
IXO842_007045	COG1515	deoxyribonuclease V activity
IXO842_007050	COG0588	phosphoglycerate mutase activity
IXO842_007065	COG3590	peptidase
IXO842_007080	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IXO842_007085	COG2199	diguanylate cyclase activity
IXO842_007085	COG2200	EAL domain
IXO842_007085	COG2202	Pas domain
IXO842_007090	COG0835	chemotaxis
IXO842_007095	COG0840	transmembrane signaling receptor activity
IXO842_007100	COG0643	Histidine kinase
IXO842_007100	COG2198	Histidine kinase
IXO842_007115	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IXO842_007125	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IXO842_007140	COG2205	protein histidine kinase activity
IXO842_007190	COG3039	Transposase
IXO842_007215	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IXO842_007220	COG0735	belongs to the Fur family
IXO842_007280	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IXO842_007285	COG0084	hydrolase, TatD family'
IXO842_007300	COG1960	acyl-CoA dehydrogenase activity
IXO842_007315	COG0367	asparagine synthase
IXO842_007325	COG0305	Participates in initiation and elongation during chromosome replication
IXO842_007330	COG0415	Belongs to the DNA photolyase family
IXO842_007345	COG1028	Short-chain dehydrogenase reductase Sdr
IXO842_007445	COG5001	Diguanylate cyclase
IXO842_007445	COG5002	protein histidine kinase activity
IXO842_007450	COG1187	pseudouridine synthase activity
IXO842_007470	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IXO842_007480	COG0475	glutathione-regulated potassium exporter activity
IXO842_007485	COG5000	phosphorelay sensor kinase activity
IXO842_007485	COG5002	protein histidine kinase activity
IXO842_007490	COG0745	RESPONSE REGULATOR receiver
IXO842_007520	COG1132	(ABC) transporter
IXO842_007545	COG3039	Transposase
IXO842_007550	COG3039	Transposase
IXO842_007565	COG3039	Transposase
IXO842_007595	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
IXO842_007605	COG4969	Belongs to the N-Me-Phe pilin family
IXO842_007610	COG2194	sulfuric ester hydrolase activity
IXO842_007650	COG0045	succinate-CoA ligase (ADP-forming) activity
IXO842_007655	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IXO842_007665	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IXO842_007665	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IXO842_007670	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IXO842_007675	COG0564	pseudouridine synthase activity
IXO842_007700	COG3387	PFAM Glycoside hydrolase 15-related
IXO842_007705	COG1877	trehalose-phosphatase activity
IXO842_007745	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
IXO842_007760	COG1595	DNA-templated transcription, initiation
IXO842_007770	COG1946	Acyl-CoA thioesterase
IXO842_007785	COG0824	Thioesterase
IXO842_007790	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IXO842_007800	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IXO842_007805	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IXO842_007810	COG0268	Binds directly to 16S ribosomal RNA
IXO842_007815	COG0728	peptidoglycan biosynthetic process
IXO842_007820	COG0196	riboflavin kinase activity
IXO842_007830	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IXO842_007835	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IXO842_007850	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IXO842_007855	COG1845	cytochrome c oxidase, subunit III
IXO842_007860	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IXO842_007880	COG3209	COG3209 Rhs family protein
IXO842_007895	COG3328	transposase activity
IXO842_008005	COG0632	four-way junction helicase activity
IXO842_008015	COG2255	four-way junction helicase activity
IXO842_008020	COG0824	Thioesterase
IXO842_008030	COG0848	biopolymer transport protein
IXO842_008045	COG2885	chlorophyll binding
IXO842_008055	COG0602	queuosine metabolic process
IXO842_008065	COG1187	pseudouridine synthase activity
IXO842_008125	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IXO842_008150	COG0514	ATP-dependent DNA helicase (RecQ)
IXO842_008155	COG0783	Belongs to the Dps family
IXO842_008160	COG1643	Atp-dependent helicase
IXO842_008200	COG0535	radical SAM domain protein
IXO842_008205	COG0535	radical SAM domain protein
IXO842_008225	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IXO842_008235	COG1215	transferase activity, transferring glycosyl groups
IXO842_008240	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IXO842_008250	COG1199	ATP-dependent helicase activity
IXO842_008260	COG1397	ADP-ribosylglycohydrolase
IXO842_008270	COG0189	ligase activity
IXO842_008285	COG0835	chemotaxis
IXO842_008290	COG0840	transmembrane signaling receptor activity
IXO842_008295	COG0643	Histidine kinase
IXO842_008295	COG0784	Response regulator, receiver
IXO842_008295	COG2198	Histidine kinase
IXO842_008315	COG3039	Transposase
IXO842_008340	COG1446	asparaginase
IXO842_008385	COG3537	Alpha-1,2-mannosidase
IXO842_008425	COG1472	Belongs to the glycosyl hydrolase 3 family
IXO842_008445	COG1388	LysM domain
IXO842_008445	COG3858	chitin binding
IXO842_008460	COG0837	glucose binding
IXO842_008465	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IXO842_008475	COG0494	nUDIX hydrolase
IXO842_008485	COG3956	TIGRFAM MazG family protein
IXO842_008500	COG0330	HflC and HflK could
IXO842_008515	COG0509	glycine decarboxylation via glycine cleavage system
IXO842_008530	COG3039	Transposase
IXO842_008550	COG1960	acyl-CoA dehydrogenase activity
IXO842_008560	COG1309	transcriptional regulator
IXO842_008565	COG4771	TonB-dependent receptor
IXO842_008575	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IXO842_008585	COG0463	Glycosyl transferase, family 2
IXO842_008605	COG1272	protein, Hemolysin III
IXO842_008615	COG0739	heme binding
IXO842_008620	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IXO842_008625	COG0626	cystathionine gamma-synthase activity
IXO842_008635	COG1760	l-serine dehydratase
IXO842_008650	COG2353	YceI-like domain
IXO842_008660	COG2353	YceI-like domain
IXO842_008705	COG3250	beta-galactosidase activity
IXO842_008710	COG3867	Arabinogalactan endo-beta-1,4-galactanase
IXO842_008730	COG1960	acyl-CoA dehydrogenase activity
IXO842_008735	COG1024	Enoyl-CoA hydratase
IXO842_008760	COG1250	3-hydroxyacyl-CoA dehydrogenase
IXO842_008760	COG1024	Enoyl-CoA hydratase
IXO842_008775	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IXO842_008805	COG1381	Involved in DNA repair and RecF pathway recombination
IXO842_008820	COG2954	triphosphatase activity
IXO842_008830	COG3039	Transposase
IXO842_008835	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IXO842_008840	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
IXO842_008845	COG3046	protein related to deoxyribodipyrimidine photolyase
IXO842_008855	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
IXO842_008860	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IXO842_008865	COG1278	Cold shock
IXO842_008885	COG1201	RNA secondary structure unwinding
IXO842_008890	COG1793	dna ligase
IXO842_008900	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
IXO842_008900	COG1793	dna ligase
IXO842_008930	COG0183	Belongs to the thiolase family
IXO842_008965	COG1451	nucleotide metabolic process
IXO842_008980	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IXO842_009015	COG1047	Peptidyl-prolyl cis-trans
IXO842_009030	COG2824	Alkylphosphonate utilization operon protein PhnA
IXO842_009040	COG1902	pentaerythritol trinitrate reductase activity
IXO842_009045	COG2814	Major facilitator Superfamily
IXO842_009075	COG3039	Transposase
IXO842_009105	COG0392	lysyltransferase activity
IXO842_009105	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IXO842_009115	COG0251	oxidation-reduction process
IXO842_009120	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IXO842_009135	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IXO842_009160	COG1595	DNA-templated transcription, initiation
IXO842_009175	COG2878	Part of a membrane complex involved in electron transport
IXO842_009185	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IXO842_009185	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IXO842_009205	COG0833	amino acid
IXO842_009210	COG2040	homocysteine
IXO842_009225	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IXO842_009265	COG2895	sulfate adenylyltransferase (ATP) activity
IXO842_009265	COG0529	Catalyzes the synthesis of activated sulfate
IXO842_009310	COG1981	membrane
IXO842_009340	COG4771	TonB-dependent receptor
IXO842_009350	COG0825	malonyl-CoA metabolic process
IXO842_009370	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IXO842_009375	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IXO842_009395	COG0750	zinc metalloprotease
IXO842_009405	COG0575	Belongs to the CDS family
IXO842_009415	COG0233	cytoplasmic translational termination
IXO842_009430	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IXO842_009490	COG1393	Belongs to the ArsC family
IXO842_009500	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IXO842_009505	COG0367	asparagine synthase
IXO842_009515	COG4774	siderophore transport
IXO842_009555	COG1566	PFAM secretion protein HlyD family protein
IXO842_009560	COG2814	Major facilitator Superfamily
IXO842_009615	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IXO842_009625	COG1960	acyl-CoA dehydrogenase activity
IXO842_009640	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IXO842_009650	COG2914	Belongs to the UPF0125 (RnfH) family
IXO842_009655	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IXO842_009665	COG0497	DNA recombination
IXO842_009675	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IXO842_009685	COG0484	heat shock protein binding
IXO842_009690	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
IXO842_009695	COG1605	Chorismate mutase
IXO842_009695	COG0287	Prephenate dehydrogenase
IXO842_009710	COG0583	DNA-binding transcription factor activity
IXO842_009725	COG1132	(ABC) transporter
IXO842_009760	COG2850	peptidyl-arginine hydroxylation
IXO842_009845	COG1131	(ABC) transporter
IXO842_009850	COG1725	Transcriptional regulator
IXO842_009860	COG0386	Belongs to the glutathione peroxidase family
IXO842_009875	COG2900	Belongs to the SlyX family
IXO842_009890	COG1609	Transcriptional regulator
IXO842_009900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IXO842_009910	COG0646	methionine synthase
IXO842_009910	COG1410	methionine synthase
IXO842_009915	COG0646	methionine synthase
IXO842_009915	COG1410	methionine synthase
IXO842_009920	COG2226	methyltransferase
IXO842_009925	COG1960	acyl-CoA dehydrogenase activity
IXO842_009950	COG0557	exoribonuclease II activity
IXO842_009970	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IXO842_009980	COG3039	Transposase
IXO842_010050	COG3842	ATPase activity
IXO842_010060	COG1177	transmembrane transport
IXO842_010070	COG1012	belongs to the aldehyde dehydrogenase family
IXO842_010085	COG4535	Mg2 and Co2 transporter CorC
IXO842_010105	COG1702	phosphate starvation-inducible protein PhoH
IXO842_010130	COG0741	lytic transglycosylase activity
IXO842_010135	COG0723	plastoquinol--plastocyanin reductase activity
IXO842_010140	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IXO842_010145	COG2857	Cytochrome c1
IXO842_010150	COG0625	glutathione transferase activity
IXO842_010155	COG2969	positive regulation of protein catabolic process
IXO842_010190	COG3328	transposase activity
IXO842_010280	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IXO842_010300	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IXO842_010305	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IXO842_010305	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IXO842_010310	COG0802	atpase or kinase
IXO842_010315	COG0860	N-Acetylmuramoyl-L-alanine amidase
IXO842_010320	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IXO842_010340	COG1028	Short-chain dehydrogenase reductase Sdr
IXO842_010350	COG0501	Belongs to the peptidase M48B family
IXO842_010360	COG2081	HI0933 family
IXO842_010365	COG4681	YaeQ
IXO842_010370	COG1671	Belongs to the UPF0178 family
IXO842_010380	COG0625	glutathione transferase activity
IXO842_010390	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
IXO842_010395	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IXO842_010400	COG0513	Belongs to the DEAD box helicase family
IXO842_010405	COG0488	(ABC) transporter
IXO842_010425	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IXO842_010430	COG0483	inositol monophosphate 1-phosphatase activity
IXO842_010445	COG3300	MHYT domain
IXO842_010445	COG5001	Diguanylate cyclase
IXO842_010450	COG1509	lysine 2,3-aminomutase activity
IXO842_010465	COG0402	S-adenosylhomocysteine deaminase activity
IXO842_010470	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IXO842_010495	COG4677	pectinesterase activity
IXO842_010505	COG3039	Transposase
IXO842_010540	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IXO842_010565	COG2166	iron-sulfur cluster assembly
IXO842_010580	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IXO842_010585	COG0137	argininosuccinate synthase activity
IXO842_010595	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IXO842_010600	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IXO842_010615	COG0165	Argininosuccinate lyase
IXO842_010635	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IXO842_010665	COG1271	oxidase subunit
IXO842_010675	COG4988	ABC transporter
IXO842_010680	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IXO842_010760	COG3039	Transposase
IXO842_010775	COG3209	COG3209 Rhs family protein
IXO842_010810	COG3039	Transposase
IXO842_010835	COG0643	Histidine kinase
IXO842_010835	COG0784	Response regulator, receiver
IXO842_010835	COG2198	Histidine kinase
IXO842_010890	COG1684	flagellar biosynthetic protein fliR
IXO842_010905	COG3190	flagellar
IXO842_010955	COG1677	Flagellar hook-basal body complex protein FliE
IXO842_010990	COG1028	Short-chain dehydrogenase reductase Sdr
IXO842_011000	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IXO842_011020	COG2201	protein-glutamate methylesterase activity
IXO842_011050	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IXO842_011055	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IXO842_011095	COG4787	bacterial-type flagellum-dependent cell motility
IXO842_011105	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
IXO842_011110	COG1558	bacterial-type flagellum-dependent cell motility
IXO842_011120	COG0784	Response regulator, receiver
IXO842_011120	COG0835	chemotaxis
IXO842_011140	COG5002	protein histidine kinase activity
IXO842_011150	COG4585	Histidine kinase
IXO842_011155	COG5001	Diguanylate cyclase
IXO842_011180	COG0482	sulfurtransferase activity
IXO842_011195	COG0542	response to heat
IXO842_011220	COG0492	ferredoxin-NADP+ reductase activity
IXO842_011225	COG1674	ftsk spoiiie
IXO842_011245	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IXO842_011265	COG0038	chloride channel
IXO842_011270	COG0183	Belongs to the thiolase family
IXO842_011275	COG1024	Enoyl-CoA hydratase
IXO842_011275	COG1250	3-hydroxyacyl-CoA dehydrogenase
IXO842_011290	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IXO842_011300	COG1426	Protein conserved in bacteria
IXO842_011310	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IXO842_011320	COG0303	'Molybdopterin
IXO842_011375	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IXO842_011415	COG0742	ribosomal rna small subunit methyltransferase
IXO842_011420	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IXO842_011430	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IXO842_011435	COG0405	Gamma-glutamyltransferase
IXO842_011460	COG3039	Transposase
IXO842_011490	COG3039	Transposase
IXO842_011545	COG0343	queuine tRNA-ribosyltransferase activity
IXO842_011550	COG1862	Preprotein translocase
IXO842_011555	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IXO842_011560	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IXO842_011595	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IXO842_011605	COG0704	Plays a role in the regulation of phosphate uptake
IXO842_011620	COG0573	inorganic phosphate transmembrane transporter activity
IXO842_011625	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IXO842_011665	COG3039	Transposase
IXO842_011685	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IXO842_011695	COG1024	Enoyl-CoA hydratase
IXO842_011705	COG0494	nUDIX hydrolase
IXO842_011750	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IXO842_011750	COG0116	Belongs to the methyltransferase superfamily
IXO842_011775	COG0667	Aldo Keto reductase
IXO842_011785	COG2925	Exonuclease
IXO842_011815	COG0288	reversible hydration of carbon dioxide
IXO842_011845	COG0316	Belongs to the HesB IscA family
IXO842_011850	COG0360	Binds together with S18 to 16S ribosomal RNA
IXO842_011860	COG0359	binds to the 23S rRNA
IXO842_011870	COG3115	cell septum assembly
IXO842_011885	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
IXO842_011900	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IXO842_011925	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IXO842_011935	COG2986	histidine ammonia-lyase
IXO842_011940	COG1228	amidohydrolase
IXO842_011980	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IXO842_011990	COG0077	Prephenate dehydratase
IXO842_011990	COG1605	Chorismate mutase
IXO842_011995	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IXO842_012020	COG3039	Transposase
IXO842_012030	COG4566	intracellular signal transduction
IXO842_012075	COG0860	N-Acetylmuramoyl-L-alanine amidase
IXO842_012080	COG1469	GTP cyclohydrolase I activity
IXO842_012090	COG0617	tRNA 3'-terminal CCA addition
IXO842_012100	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IXO842_012105	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IXO842_012135	COG1472	Belongs to the glycosyl hydrolase 3 family
IXO842_012155	COG5001	Diguanylate cyclase
IXO842_012155	COG4251	negative regulation of phosphorylation
IXO842_012155	COG3706	GGDEF domain
IXO842_012155	COG2203	Gaf domain
IXO842_012240	COG0386	Belongs to the glutathione peroxidase family
IXO842_012310	COG3039	Transposase
IXO842_012325	COG2205	protein histidine kinase activity
IXO842_012325	COG5002	protein histidine kinase activity
IXO842_012325	COG0784	Response regulator, receiver
IXO842_012365	COG0800	Aldolase
IXO842_012370	COG0129	dihydroxy-acid dehydratase activity
IXO842_012375	COG0363	glucosamine-6-phosphate deaminase activity
IXO842_012385	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IXO842_012400	COG0354	folic acid binding
IXO842_012415	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IXO842_012430	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IXO842_012445	COG4591	ABC-type transport system involved in lipoprotein release permease component
IXO842_012470	COG0811	peptide transport
IXO842_012485	COG1663	tetraacyldisaccharide 4'-kinase activity
IXO842_012495	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IXO842_012505	COG0322	excinuclease ABC activity
IXO842_012540	COG3328	transposase activity
IXO842_012575	COG2801	Transposase and inactivated derivatives
IXO842_012660	COG0653	protein targeting
IXO842_012695	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IXO842_012695	COG0140	phosphoribosyl-ATP diphosphatase activity
IXO842_012705	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IXO842_012715	COG0131	Imidazoleglycerol-phosphate dehydratase
IXO842_012715	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IXO842_012730	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IXO842_012750	COG0124	histidyl-tRNA synthetase
IXO842_012770	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IXO842_012810	COG1012	belongs to the aldehyde dehydrogenase family
IXO842_012825	COG0167	dihydroorotate dehydrogenase activity
IXO842_012830	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IXO842_012835	COG0697	spore germination
IXO842_012840	COG1794	racemase activity, acting on amino acids and derivatives
IXO842_012865	COG0671	phosphoesterase, PA-phosphatase related
IXO842_012880	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
IXO842_012895	COG2183	response to ionizing radiation
IXO842_012905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IXO842_012905	COG0723	plastoquinol--plastocyanin reductase activity
IXO842_012920	COG3243	poly(R)-hydroxyalkanoic acid synthase
IXO842_012930	COG1183	phosphatidylcholine synthase activity
IXO842_012935	COG1028	Short-chain dehydrogenase reductase Sdr
IXO842_012950	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
IXO842_012960	COG0668	transmembrane transport
IXO842_012980	COG1914	H( )-stimulated, divalent metal cation uptake system
IXO842_013025	COG0583	DNA-binding transcription factor activity
IXO842_013030	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IXO842_013035	COG3002	Belongs to the UPF0753 family
IXO842_013130	COG0582	viral genome integration into host DNA
IXO842_013145	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IXO842_013165	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IXO842_013175	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IXO842_013180	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
IXO842_013190	COG0776	regulation of translation
IXO842_013195	COG0539	negative regulation of cytoplasmic translation
IXO842_013200	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IXO842_013215	COG2957	Belongs to the agmatine deiminase family
IXO842_013225	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IXO842_013250	COG0395	ABC-type sugar transport system, permease component
IXO842_013255	COG1175	transmembrane transport
IXO842_013285	COG2350	Protein conserved in bacteria
IXO842_013290	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IXO842_013295	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IXO842_013300	COG1187	pseudouridine synthase activity
IXO842_013325	COG0436	Aminotransferase
IXO842_013390	COG0277	FAD linked oxidase domain protein
IXO842_013395	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IXO842_013405	COG0531	amino acid
IXO842_013410	COG0531	amino acid
IXO842_013415	COG0235	Class ii aldolase
IXO842_013420	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
IXO842_013510	COG0583	DNA-binding transcription factor activity
IXO842_013520	COG3039	Transposase
IXO842_013600	COG0174	glutamine synthetase
IXO842_013605	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IXO842_013615	COG0477	Major facilitator Superfamily
IXO842_013625	COG0243	molybdopterin cofactor binding
IXO842_013635	COG2223	nitrite transmembrane transporter activity
IXO842_013645	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IXO842_013650	COG1121	(ABC) transporter
IXO842_013660	COG2733	membrane
IXO842_013665	COG5002	protein histidine kinase activity
IXO842_013665	COG2205	protein histidine kinase activity
IXO842_013665	COG0784	Response regulator, receiver
IXO842_013675	COG3039	Transposase
IXO842_013680	COG2902	Dehydrogenase
IXO842_013690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IXO842_013695	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IXO842_013720	COG1609	Transcriptional regulator
IXO842_013725	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IXO842_013725	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IXO842_013730	COG1105	Belongs to the carbohydrate kinase PfkB family
IXO842_013735	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IXO842_013735	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IXO842_013750	COG3039	Transposase
IXO842_013780	COG3039	Transposase
IXO842_013870	COG4771	TonB-dependent receptor
IXO842_013880	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IXO842_013900	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IXO842_013905	COG1360	Flagellar Motor Protein
IXO842_013915	COG0835	chemotaxis
IXO842_013925	COG0745	RESPONSE REGULATOR receiver
IXO842_013950	COG0840	transmembrane signaling receptor activity
IXO842_013960	COG0840	transmembrane signaling receptor activity
IXO842_013970	COG0840	transmembrane signaling receptor activity
IXO842_013980	COG0840	transmembrane signaling receptor activity
IXO842_013985	COG0840	transmembrane signaling receptor activity
IXO842_013990	COG0840	transmembrane signaling receptor activity
IXO842_013995	COG0840	transmembrane signaling receptor activity
IXO842_014010	COG0835	chemotaxis
IXO842_014030	COG3039	Transposase
IXO842_014085	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IXO842_014115	COG0318	PFAM AMP-dependent synthetase and ligase
IXO842_014120	COG1024	Enoyl-CoA hydratase
IXO842_014125	COG0784	Response regulator, receiver
IXO842_014125	COG2198	Histidine kinase
IXO842_014125	COG2205	protein histidine kinase activity
IXO842_014135	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IXO842_014195	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IXO842_014205	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IXO842_014210	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IXO842_014220	COG0505	Belongs to the CarA family
IXO842_014225	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IXO842_014235	COG2258	MOSC domain
IXO842_014240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IXO842_014290	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IXO842_014310	COG0477	Major facilitator Superfamily
IXO842_014320	COG1070	Carbohydrate kinase
IXO842_014330	COG1501	Belongs to the glycosyl hydrolase 31 family
IXO842_014345	COG0800	Aldolase
IXO842_014350	COG4948	Mandelate Racemase Muconate Lactonizing
IXO842_014360	COG3734	2-keto-3-deoxy-galactonokinase
IXO842_014365	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IXO842_014375	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IXO842_014390	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IXO842_014395	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
IXO842_014405	COG0351	phosphomethylpyrimidine kinase
IXO842_014435	COG0583	DNA-binding transcription factor activity
IXO842_014440	COG1741	Belongs to the pirin family
IXO842_014460	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IXO842_014465	COG0305	Participates in initiation and elongation during chromosome replication
IXO842_014490	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IXO842_014495	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IXO842_014500	COG2137	regulation of response to DNA damage stimulus
IXO842_014505	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IXO842_014520	COG1546	Belongs to the CinA family
IXO842_014525	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IXO842_014535	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IXO842_014540	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IXO842_014550	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
IXO842_014555	COG1534	Rna-binding protein
IXO842_014570	COG1238	metal cluster binding
IXO842_014575	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IXO842_014580	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
IXO842_014585	COG2840	Smr protein MutS2
IXO842_014595	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
IXO842_014605	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
IXO842_014610	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IXO842_014615	COG0148	phosphopyruvate hydratase activity
IXO842_014625	COG2877	3-deoxy-8-phosphooctulonate synthase activity
IXO842_014630	COG0504	CTP synthase activity
IXO842_014660	COG0306	phosphate transporter
IXO842_014670	COG1253	flavin adenine dinucleotide binding
IXO842_014685	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IXO842_014695	COG0477	Major facilitator Superfamily
IXO842_014705	COG1132	(ABC) transporter
IXO842_014710	COG1136	(ABC) transporter
IXO842_014725	COG0438	transferase activity, transferring glycosyl groups
IXO842_014735	COG2264	protein methyltransferase activity
IXO842_014765	COG2244	polysaccharide biosynthetic process
IXO842_014815	COG1595	DNA-templated transcription, initiation
IXO842_014830	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IXO842_014850	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IXO842_014900	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IXO842_014955	COG1858	cytochrome C peroxidase
IXO842_014985	COG0515	serine threonine protein kinase
IXO842_014990	COG0631	protein serine/threonine phosphatase activity
IXO842_015110	COG3039	Transposase
IXO842_015175	COG2154	pterin-4-alpha-carbinolamine dehydratase
IXO842_015185	COG0428	transporter
IXO842_015190	COG0428	transporter
IXO842_015195	COG3064	Membrane
IXO842_015205	COG1530	ribonuclease E activity
IXO842_015220	COG1054	Belongs to the UPF0176 family
IXO842_015240	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IXO842_015280	COG3039	Transposase
IXO842_015290	COG3039	Transposase
IXO842_015330	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IXO842_015330	COG1648	precorrin-2 dehydrogenase activity
IXO842_015355	COG0746	molybdenum cofactor guanylyltransferase activity
IXO842_015440	COG4206	TonB-dependent receptor
IXO842_015490	COG0531	amino acid
IXO842_015505	COG0006	proline dipeptidase activity
IXO842_015515	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IXO842_015530	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IXO842_015535	COG3938	Belongs to the proline racemase family
IXO842_015545	COG0552	protein localization to endoplasmic reticulum
IXO842_015555	COG1194	a g-specific adenine glycosylase
IXO842_015565	COG0784	Response regulator, receiver
IXO842_015565	COG4191	Histidine kinase
IXO842_015635	COG3039	Transposase
IXO842_015665	COG3040	lipid binding
IXO842_015710	COG0438	transferase activity, transferring glycosyl groups
IXO842_015720	COG0438	transferase activity, transferring glycosyl groups
IXO842_015725	COG0438	transferase activity, transferring glycosyl groups
IXO842_015780	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IXO842_015795	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IXO842_015830	COG0556	nucleotide-excision repair
IXO842_015835	COG4969	Belongs to the N-Me-Phe pilin family
IXO842_015875	COG1611	Belongs to the LOG family
IXO842_015890	COG2095	MarC family integral membrane protein
IXO842_015900	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IXO842_015935	COG1185	polyribonucleotide nucleotidyltransferase activity
IXO842_015940	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IXO842_015960	COG0195	Participates in both transcription termination and antitermination
IXO842_015965	COG0779	Required for maturation of 30S ribosomal subunits
IXO842_015975	COG1007	ATP synthesis coupled electron transport
IXO842_016005	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
IXO842_016010	COG1034	ATP synthesis coupled electron transport
IXO842_016015	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IXO842_016020	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
IXO842_016025	COG0649	NAD binding
IXO842_016030	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IXO842_016040	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IXO842_016055	COG0149	triose-phosphate isomerase activity
IXO842_016110	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IXO842_016115	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IXO842_016120	COG0159	tryptophan synthase activity
IXO842_016140	COG0135	phosphoribosylanthranilate isomerase activity
IXO842_016145	COG0101	tRNA pseudouridine synthase activity
IXO842_016165	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IXO842_016170	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IXO842_016175	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IXO842_016180	COG2890	protein-(glutamine-N5) methyltransferase activity
IXO842_016205	COG0433	COG0433 Predicted ATPase
IXO842_016210	COG2826	transposase and inactivated derivatives, IS30 family
IXO842_016225	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IXO842_016235	COG0412	Dienelactone hydrolase
IXO842_016255	COG0717	Belongs to the dCTP deaminase family
IXO842_016260	COG0489	protein tyrosine kinase activity
IXO842_016300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IXO842_016305	COG2311	Membrane
IXO842_016310	COG1047	Peptidyl-prolyl cis-trans
IXO842_016315	COG0791	NLP P60 protein
IXO842_016320	COG0791	NLP P60 protein
IXO842_016335	COG1301	dicarboxylic acid transport
IXO842_016340	COG1785	Belongs to the alkaline phosphatase family
IXO842_016345	COG0037	tRNA processing
IXO842_016350	COG1722	exodeoxyribonuclease VII activity
IXO842_016355	COG0142	geranyltranstransferase activity
IXO842_016380	COG0312	modulator of DNA gyrase
IXO842_016385	COG3028	Belongs to the UPF0307 family
IXO842_016390	COG0312	modulator of DNA gyrase
IXO842_016400	COG3164	Protein of unknown function
IXO842_016415	COG2968	Membrane
IXO842_016445	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IXO842_016470	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IXO842_016495	COG3118	belongs to the thioredoxin family
IXO842_016535	COG3039	Transposase
IXO842_016575	COG3039	Transposase
IXO842_016675	COG2022	thiamine diphosphate biosynthetic process
IXO842_016685	COG0471	metal ion transport
IXO842_016685	COG3273	potassium ion transport
IXO842_016715	COG1970	mechanosensitive ion channel activity
IXO842_016735	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IXO842_016755	COG0308	aminopeptidase N
IXO842_016760	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IXO842_016770	COG2895	sulfate adenylyltransferase (ATP) activity
IXO842_016770	COG0529	Catalyzes the synthesis of activated sulfate
IXO842_016775	COG0175	sulfate reduction
IXO842_016780	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IXO842_016785	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IXO842_016790	COG0175	sulfate reduction
IXO842_016810	COG0784	Response regulator, receiver
IXO842_016810	COG2205	protein histidine kinase activity
IXO842_016810	COG2198	Histidine kinase
IXO842_016860	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
IXO842_016865	COG3588	fructose-bisphosphate aldolase
IXO842_016870	COG0469	pyruvate kinase activity
IXO842_016910	COG0753	catalase activity
IXO842_016935	COG1917	Cupin 2, conserved barrel domain protein
IXO842_016935	COG2207	Transcriptional regulator
IXO842_016955	COG0823	Involved in the tonB-independent uptake of proteins
IXO842_016955	COG1506	peptidase
IXO842_016975	COG1297	OPT oligopeptide transporter protein
IXO842_016990	COG0587	DNA-directed DNA polymerase activity
IXO842_017065	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
IXO842_017070	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
IXO842_017075	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
IXO842_017080	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
IXO842_017100	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
IXO842_017160	COG3039	Transposase
IXO842_017290	COG3179	chitinase
IXO842_017315	COG3039	Transposase
IXO842_017415	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IXO842_017425	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IXO842_017520	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IXO842_017535	COG2197	response regulator
IXO842_017540	COG4585	Histidine kinase
IXO842_017555	COG2894	cell division
IXO842_017560	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
IXO842_017570	COG0642	Histidine kinase
IXO842_017575	COG0745	RESPONSE REGULATOR receiver
IXO842_017580	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IXO842_017590	COG2194	sulfuric ester hydrolase activity
IXO842_017620	COG3551	Protein conserved in bacteria
IXO842_017680	COG0203	ribosomal protein L17
IXO842_017690	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IXO842_017695	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IXO842_017705	COG0201	protein transport
IXO842_017715	COG1841	ribosomal large subunit assembly
IXO842_017725	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IXO842_017745	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IXO842_017755	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IXO842_017760	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IXO842_017765	COG0255	Belongs to the universal ribosomal protein uL29 family
IXO842_017770	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IXO842_017780	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IXO842_017795	COG0089	rRNA binding
IXO842_017800	COG0088	Forms part of the polypeptide exit tunnel
IXO842_017805	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IXO842_017810	COG0051	transcription antitermination factor activity, RNA binding
IXO842_017830	COG0049	tRNA binding
IXO842_017835	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IXO842_017840	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IXO842_017845	COG0085	RNA polymerase activity
IXO842_017850	COG0222	ribosome binding
IXO842_017855	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IXO842_017865	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IXO842_017870	COG0250	Participates in transcription elongation, termination and antitermination
IXO842_017875	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IXO842_017905	COG0012	GTP binding
IXO842_017910	COG0193	aminoacyl-tRNA hydrolase activity
IXO842_017920	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IXO842_017935	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
IXO842_017945	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IXO842_017950	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IXO842_017965	COG0521	Mo-molybdopterin cofactor biosynthetic process
IXO842_017985	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IXO842_017990	COG1295	ribonuclease BN
IXO842_018020	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IXO842_018025	COG1404	Belongs to the peptidase S8 family
IXO842_018040	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IXO842_018065	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
IXO842_018090	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
IXO842_018105	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IXO842_018105	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IXO842_018155	COG2890	protein-(glutamine-N5) methyltransferase activity
IXO842_018165	COG3634	alkyl hydroperoxide reductase activity
IXO842_018170	COG0583	DNA-binding transcription factor activity
IXO842_018180	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IXO842_018205	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IXO842_018240	COG0584	glycerophosphoryl diester phosphodiesterase
IXO842_018260	COG3039	Transposase
IXO842_018275	COG0625	glutathione transferase activity
IXO842_018280	COG0039	L-malate dehydrogenase activity
IXO842_018285	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IXO842_018290	COG1217	gtp-binding protein TYPA
IXO842_018310	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
IXO842_018445	COG3781	membrane
IXO842_018455	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IXO842_018485	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
IXO842_018505	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IXO842_018530	COG3710	Transcriptional regulator
IXO842_018535	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IXO842_018545	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IXO842_018575	COG2226	methyltransferase
IXO842_018580	COG0066	3-isopropylmalate dehydratase activity
IXO842_018585	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IXO842_018615	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IXO842_018620	COG1538	Outer membrane efflux protein
IXO842_018625	COG1519	Transferase
IXO842_018630	COG1560	Kdo2-lipid A biosynthetic process
IXO842_018685	COG0308	aminopeptidase N
IXO842_018690	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IXO842_018700	COG0330	HflC and HflK could
IXO842_018705	COG0330	HflC and HflK could
IXO842_018725	COG0678	peroxiredoxin activity
IXO842_018735	COG2826	transposase and inactivated derivatives, IS30 family
IXO842_018765	COG3039	Transposase
IXO842_018795	COG3829	transcription factor binding
IXO842_018830	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IXO842_018835	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IXO842_018845	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IXO842_018850	COG1028	Short-chain dehydrogenase reductase Sdr
IXO842_018875	COG1399	metal-binding, possibly nucleic acid-binding protein
IXO842_018895	COG3039	Transposase
IXO842_018935	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IXO842_018975	COG3039	Transposase
IXO842_018985	COG2188	Transcriptional regulator
IXO842_019000	COG1450	Type ii and iii secretion system protein
IXO842_019015	COG3166	PFAM Fimbrial assembly family protein
IXO842_019020	COG3156	type II secretion system protein K
IXO842_019025	COG4795	General secretion pathway protein
IXO842_019030	COG2165	general secretion pathway protein
IXO842_019035	COG4970	Tfp pilus assembly protein FimT
IXO842_019040	COG2165	general secretion pathway protein
IXO842_019045	COG1459	type II secretion system
IXO842_019055	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IXO842_019065	COG5295	Hep Hag repeat protein
IXO842_019070	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IXO842_019070	COG0047	phosphoribosylformylglycinamidine synthase activity
IXO842_019075	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IXO842_019080	COG4974	Belongs to the 'phage' integrase family
IXO842_019090	COG0795	lipopolysaccharide-transporting ATPase activity
IXO842_019100	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IXO842_019115	COG0525	valine-tRNA ligase activity
IXO842_019150	COG3039	Transposase
IXO842_019185	COG3039	Transposase
IXO842_019215	COG1183	phosphatidylcholine synthase activity
IXO842_019225	COG0442	prolyl-tRNA aminoacylation
IXO842_019240	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IXO842_019245	COG1127	ABC transporter
IXO842_019250	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IXO842_019250	COG3218	ABC-type transport auxiliary lipoprotein component
IXO842_019285	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IXO842_019290	COG0662	Cupin 2, conserved barrel domain protein
IXO842_019290	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
IXO842_019315	COG2086	electron transfer activity
IXO842_019340	COG3328	transposase activity
IXO842_019380	COG0626	cystathionine gamma-synthase activity
IXO842_019410	COG0625	glutathione transferase activity
IXO842_019425	COG0513	Belongs to the DEAD box helicase family
IXO842_019430	COG0720	synthase
IXO842_019440	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IXO842_019445	COG1956	GAF domain-containing protein
IXO842_019485	COG0339	signal peptide processing
IXO842_019535	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IXO842_019540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IXO842_019590	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IXO842_019595	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IXO842_019600	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IXO842_019605	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IXO842_019615	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IXO842_019625	COG0356	it plays a direct role in the translocation of protons across the membrane
IXO842_019645	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IXO842_019655	COG0508	dehydrogenase complex catalyzes the overall conversion of
IXO842_019685	COG2011	ABC-type metal ion transport system permease component
IXO842_019695	COG0697	spore germination
IXO842_019730	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IXO842_019735	COG1187	pseudouridine synthase activity
IXO842_019740	COG2813	Specifically methylates the guanine in position
IXO842_019770	COG2202	Pas domain
IXO842_019770	COG2205	protein histidine kinase activity
IXO842_019795	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IXO842_019845	COG0745	RESPONSE REGULATOR receiver
IXO842_019860	COG1404	Belongs to the peptidase S8 family
IXO842_019880	COG0842	Transport permease protein
IXO842_019885	COG1131	(ABC) transporter
IXO842_019890	COG0025	NhaP-type Na H and K H
IXO842_019900	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
IXO842_019910	COG1573	uracil-dna glycosylase
IXO842_019920	COG3384	dioxygenase
IXO842_019935	COG0667	Aldo Keto reductase
IXO842_019950	COG3590	peptidase
IXO842_019970	COG0531	amino acid
IXO842_019995	COG2972	Histidine kinase
IXO842_020045	COG1271	oxidase subunit
IXO842_020195	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IXO842_020205	COG1560	Kdo2-lipid A biosynthetic process
IXO842_020255	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IXO842_020255	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IXO842_020260	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IXO842_020265	COG0242	peptide deformylase activity
IXO842_020270	COG1652	LysM domain
IXO842_020275	COG0758	DNA mediated transformation
IXO842_020280	COG2922	Belongs to the Smg family
IXO842_020295	COG1754	DNA topoisomerase type I activity
IXO842_020295	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IXO842_020300	COG0009	L-threonylcarbamoyladenylate synthase
IXO842_020315	COG1028	Short-chain dehydrogenase reductase Sdr
IXO842_020325	COG0616	signal peptide processing
IXO842_020330	COG0534	Mate efflux family protein
IXO842_020350	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IXO842_020385	COG1324	tolerance protein
IXO842_020395	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
IXO842_020400	COG0511	ligase activity, forming carbon-carbon bonds
IXO842_020410	COG0439	Biotin carboxylase
IXO842_020455	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
IXO842_020520	COG3039	Transposase
IXO842_020545	COG3039	Transposase
IXO842_020635	COG3210	domain, Protein
IXO842_020640	COG2831	hemolysin activation secretion protein
IXO842_020670	COG2267	carboxylic ester hydrolase activity
IXO842_020680	COG2267	carboxylic ester hydrolase activity
IXO842_020690	COG0138	bifunctional purine biosynthesis protein purh
IXO842_020700	COG0151	Belongs to the GarS family
IXO842_020725	COG1289	transmembrane transporter activity
IXO842_020740	COG2814	Major facilitator Superfamily
IXO842_020755	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
IXO842_020790	COG0745	RESPONSE REGULATOR receiver
IXO842_020835	COG0739	heme binding
IXO842_020850	COG2211	Major facilitator Superfamily
IXO842_020855	COG0708	Exodeoxyribonuclease III
IXO842_020870	COG1192	Involved in chromosome partitioning
IXO842_020875	COG1475	DNA binding
IXO842_020890	COG0463	Glycosyl transferase, family 2
IXO842_020915	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IXO842_020925	COG0018	arginyl-trna synthetase
IXO842_020940	COG4221	oxidoreductase activity
IXO842_020965	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IXO842_020970	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IXO842_020985	COG3485	protocatechuate 3,4-dioxygenase
IXO842_020990	COG3485	protocatechuate 3,4-dioxygenase
IXO842_021025	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IXO842_021030	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IXO842_021040	COG0045	succinate-CoA ligase (ADP-forming) activity
IXO842_021040	COG1042	CoA-binding domain protein
IXO842_021040	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IXO842_021055	COG2239	Acts as a magnesium transporter
IXO842_021070	COG3039	Transposase
IXO842_021080	COG3328	transposase activity
IXO842_021085	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IXO842_021085	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IXO842_021095	COG1473	amidohydrolase
IXO842_021100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IXO842_021105	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IXO842_021120	COG5383	Protein conserved in bacteria
IXO842_021150	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IXO842_021155	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
IXO842_021170	COG0028	Belongs to the TPP enzyme family
IXO842_021175	COG4191	Histidine kinase
IXO842_021200	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IXO842_021215	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IXO842_021220	COG3177	Filamentation induced by cAMP protein fic
IXO842_021235	COG0596	Alpha beta hydrolase
IXO842_021240	COG0727	PFAM Uncharacterised protein family (UPF0153)
IXO842_021245	COG0318	PFAM AMP-dependent synthetase and ligase
IXO842_021250	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IXO842_021300	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IXO842_021310	COG0129	dihydroxy-acid dehydratase activity
IXO842_021335	COG3039	Transposase
IXO842_021345	COG0408	coproporphyrinogen oxidase activity
IXO842_021385	COG0232	Belongs to the dGTPase family. Type 2 subfamily
IXO842_021445	COG2353	YceI-like domain
IXO842_021475	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IXO842_021490	COG3386	PFAM SMP-30 Gluconolaconase
IXO842_021530	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IXO842_021545	COG4771	TonB-dependent receptor
IXO842_021555	COG0459	protein refolding
IXO842_021580	COG1252	NADH dehydrogenase
IXO842_021590	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IXO842_021595	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IXO842_021600	COG3437	response regulator, receiver
IXO842_021605	COG2177	Part of the ABC transporter FtsEX involved in
IXO842_021610	COG2884	Cell division ATP-binding protein ftsE
IXO842_021620	COG3118	belongs to the thioredoxin family
IXO842_021625	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IXO842_021640	COG0729	surface antigen
IXO842_021645	COG2911	Protein conserved in bacteria
IXO842_021680	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IXO842_021695	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IXO842_021745	COG1733	regulation of RNA biosynthetic process
IXO842_021750	COG0702	epimerase
IXO842_021780	COG0583	DNA-binding transcription factor activity
IXO842_021785	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IXO842_021805	COG0745	RESPONSE REGULATOR receiver
IXO842_021835	COG1902	pentaerythritol trinitrate reductase activity
IXO842_021840	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IXO842_021850	COG2814	Major facilitator Superfamily
IXO842_021855	COG0583	DNA-binding transcription factor activity
IXO842_021870	COG0084	hydrolase, TatD family'
IXO842_021915	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IXO842_021935	COG2072	flavoprotein involved in K transport
IXO842_021990	COG4770	biotin carboxylase activity
IXO842_021995	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IXO842_022000	COG1960	acyl-CoA dehydrogenase activity
IXO842_022050	COG0523	cobalamin synthesis protein
IXO842_022060	COG0697	spore germination
IXO842_022070	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IXO842_022085	COG4771	TonB-dependent receptor
IXO842_022090	COG0457	Tetratricopeptide repeat
IXO842_022100	COG0752	glycyl-tRNA synthetase alpha subunit
IXO842_022105	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IXO842_022120	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IXO842_022120	COG0519	Catalyzes the synthesis of GMP from XMP
IXO842_022130	COG0805	protein transport
IXO842_022140	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IXO842_022150	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
IXO842_022175	COG2974	May be involved in recombination
IXO842_022180	COG0037	tRNA processing
IXO842_022195	COG3661	Belongs to the glycosyl hydrolase 67 family
IXO842_022205	COG4948	Mandelate Racemase Muconate Lactonizing
IXO842_022215	COG1472	Belongs to the glycosyl hydrolase 3 family
IXO842_022220	COG0246	Mannitol dehydrogenase
IXO842_022245	COG3693	PFAM glycoside hydrolase, family 10
IXO842_022265	COG2211	Major facilitator Superfamily
IXO842_022315	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IXO842_022355	COG1846	Transcriptional regulator
IXO842_022360	COG1764	response to oxidative stress
IXO842_022440	COG3549	Plasmid maintenance system killer
IXO842_022450	COG1074	ATP-dependent DNA helicase activity
IXO842_022455	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IXO842_022500	COG2032	superoxide dismutase activity
IXO842_022505	COG2032	superoxide dismutase activity
IXO842_022510	COG2204	response regulator
IXO842_022515	COG3852	Histidine kinase
IXO842_022520	COG0004	ammonium transporteR
IXO842_022525	COG0347	Belongs to the P(II) protein family
IXO842_022530	COG0174	glutamine synthetase
IXO842_022535	COG1968	undecaprenyl-diphosphatase activity
IXO842_022580	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IXO842_022590	COG2062	phosphohistidine phosphatase, SixA
IXO842_022595	COG0489	protein tyrosine kinase activity
IXO842_022615	COG1396	sequence-specific DNA binding
IXO842_022620	COG3550	peptidyl-serine autophosphorylation
IXO842_022625	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
IXO842_022630	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IXO842_022645	COG1125	glycine betaine transport
IXO842_022645	COG0517	IMP dehydrogenase activity
IXO842_022660	COG1119	ATPase activity
IXO842_022670	COG1752	Esterase of the alpha-beta hydrolase superfamily
IXO842_022685	COG3039	Transposase
IXO842_022710	COG0656	L-ascorbic acid biosynthetic process
IXO842_022715	COG2130	NADP-dependent
IXO842_022720	COG0667	Aldo Keto reductase
IXO842_022730	COG1187	pseudouridine synthase activity
IXO842_022745	COG1643	Atp-dependent helicase
IXO842_022750	COG4807	Protein conserved in bacteria
IXO842_022755	COG4948	Mandelate Racemase Muconate Lactonizing
IXO842_022760	COG0179	Fumarylacetoacetate (FAA) hydrolase
IXO842_022765	COG1028	Short-chain dehydrogenase reductase Sdr
IXO842_022785	COG3507	Belongs to the glycosyl hydrolase 43 family
IXO842_022825	COG3162	membrane
IXO842_022830	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IXO842_022850	COG0708	Exodeoxyribonuclease III
IXO842_022865	COG2091	lysine biosynthetic process via aminoadipic acid
IXO842_022875	COG3540	Alkaline phosphatase
IXO842_022880	COG0357	Ribosomal RNA small subunit methyltransferase G
IXO842_022905	COG2159	amidohydrolase
IXO842_022915	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IXO842_022920	COG0583	DNA-binding transcription factor activity
IXO842_022925	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IXO842_022940	COG0210	DNA helicase
IXO842_022965	COG0531	amino acid
IXO842_022970	COG1322	Protein conserved in bacteria
IXO842_022980	COG0386	Belongs to the glutathione peroxidase family
IXO842_023040	COG0793	Belongs to the peptidase S41A family
IXO842_023045	COG4942	peptidase
IXO842_023055	COG2234	aminopeptidase activity
IXO842_023100	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IXO842_023105	COG0302	gtp cyclohydrolase
IXO842_023125	COG0477	Major facilitator Superfamily
IXO842_023230	COG3039	Transposase
IXO842_023240	COG1929	Belongs to the glycerate kinase type-1 family
IXO842_023245	COG2271	Major facilitator Superfamily
IXO842_023260	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IXO842_023265	COG0861	Integral membrane protein TerC family
IXO842_023280	COG0584	glycerophosphoryl diester phosphodiesterase
IXO842_023290	COG0671	phosphoesterase, PA-phosphatase related
IXO842_023300	COG0726	polysaccharide deacetylase
IXO842_023305	COG0706	membrane insertase activity
IXO842_023330	COG2948	multi-organism process
IXO842_023335	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
IXO842_023350	COG0741	lytic transglycosylase activity
IXO842_023365	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IXO842_023395	COG1475	DNA binding
IXO842_023400	COG1192	Involved in chromosome partitioning
IXO842_023445	COG3451	type IV secretory pathway VirB4
IXO842_023460	COG3704	protein secretion by the type IV secretion system