locus-tag	class	description
BRM78_00010	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BRM78_00025	COG0726	polysaccharide deacetylase
BRM78_00035	COG0671	phosphoesterase, PA-phosphatase related
BRM78_00045	COG0584	glycerophosphoryl diester phosphodiesterase
BRM78_00055	COG0861	Integral membrane protein TerC family
BRM78_00065	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BRM78_00080	COG2271	Major facilitator Superfamily
BRM78_00085	COG1929	Belongs to the glycerate kinase type-1 family
BRM78_00190	COG0477	Major facilitator Superfamily
BRM78_00215	COG0302	gtp cyclohydrolase
BRM78_00220	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BRM78_00270	COG2234	aminopeptidase activity
BRM78_00280	COG4942	peptidase
BRM78_00285	COG0793	Belongs to the peptidase S41A family
BRM78_00340	COG0386	Belongs to the glutathione peroxidase family
BRM78_00350	COG1322	Protein conserved in bacteria
BRM78_00360	COG0531	amino acid
BRM78_00375	COG0210	DNA helicase
BRM78_00395	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BRM78_00400	COG0583	DNA-binding transcription factor activity
BRM78_00405	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BRM78_00430	COG2159	amidohydrolase
BRM78_00435	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BRM78_00440	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BRM78_00460	COG3540	Alkaline phosphatase
BRM78_00470	COG2091	lysine biosynthetic process via aminoadipic acid
BRM78_00485	COG0708	Exodeoxyribonuclease III
BRM78_00500	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BRM78_00505	COG3162	membrane
BRM78_00550	COG3507	Belongs to the glycosyl hydrolase 43 family
BRM78_00570	COG1028	Short-chain dehydrogenase reductase Sdr
BRM78_00575	COG0179	Fumarylacetoacetate (FAA) hydrolase
BRM78_00585	COG4948	Mandelate Racemase Muconate Lactonizing
BRM78_00590	COG4807	Protein conserved in bacteria
BRM78_00595	COG1643	Atp-dependent helicase
BRM78_00610	COG1187	pseudouridine synthase activity
BRM78_00620	COG0667	Aldo Keto reductase
BRM78_00625	COG2130	NADP-dependent
BRM78_00630	COG0656	L-ascorbic acid biosynthetic process
BRM78_00655	COG3039	Transposase
BRM78_00670	COG1752	Esterase of the alpha-beta hydrolase superfamily
BRM78_00680	COG1119	ATPase activity
BRM78_00695	COG1125	glycine betaine transport
BRM78_00695	COG0517	IMP dehydrogenase activity
BRM78_00710	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BRM78_00715	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
BRM78_00720	COG3550	peptidyl-serine autophosphorylation
BRM78_00725	COG1396	sequence-specific DNA binding
BRM78_00745	COG0489	protein tyrosine kinase activity
BRM78_00750	COG2062	phosphohistidine phosphatase, SixA
BRM78_00760	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BRM78_00810	COG0174	glutamine synthetase
BRM78_00815	COG0347	Belongs to the P(II) protein family
BRM78_00820	COG0004	ammonium transporteR
BRM78_00825	COG3852	Histidine kinase
BRM78_00830	COG2204	response regulator
BRM78_00835	COG2032	superoxide dismutase activity
BRM78_00840	COG2032	superoxide dismutase activity
BRM78_00880	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BRM78_00885	COG1074	ATP-dependent DNA helicase activity
BRM78_00895	COG3549	Plasmid maintenance system killer
BRM78_00995	COG1764	response to oxidative stress
BRM78_01000	COG1846	Transcriptional regulator
BRM78_01050	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BRM78_01095	COG2211	Major facilitator Superfamily
BRM78_01120	COG3693	PFAM glycoside hydrolase, family 10
BRM78_01145	COG0246	Mannitol dehydrogenase
BRM78_01150	COG1472	Belongs to the glycosyl hydrolase 3 family
BRM78_01160	COG4948	Mandelate Racemase Muconate Lactonizing
BRM78_01170	COG3661	Belongs to the glycosyl hydrolase 67 family
BRM78_01225	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BRM78_01235	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BRM78_01245	COG0805	protein transport
BRM78_01255	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BRM78_01255	COG0519	Catalyzes the synthesis of GMP from XMP
BRM78_01280	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BRM78_01295	COG0457	Tetratricopeptide repeat
BRM78_01300	COG4771	TonB-dependent receptor
BRM78_01315	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BRM78_01325	COG0697	spore germination
BRM78_01335	COG0523	cobalamin synthesis protein
BRM78_01390	COG1960	acyl-CoA dehydrogenase activity
BRM78_01395	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BRM78_01470	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BRM78_01520	COG0084	hydrolase, TatD family'
BRM78_01540	COG0583	DNA-binding transcription factor activity
BRM78_01545	COG2814	Major facilitator Superfamily
BRM78_01555	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BRM78_01560	COG1902	pentaerythritol trinitrate reductase activity
BRM78_01590	COG0745	RESPONSE REGULATOR receiver
BRM78_01610	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BRM78_01615	COG0583	DNA-binding transcription factor activity
BRM78_01645	COG0702	epimerase
BRM78_01650	COG1733	regulation of RNA biosynthetic process
BRM78_01710	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BRM78_01725	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BRM78_01760	COG2911	Protein conserved in bacteria
BRM78_01765	COG0729	surface antigen
BRM78_01780	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BRM78_01785	COG3118	belongs to the thioredoxin family
BRM78_01795	COG2884	Cell division ATP-binding protein ftsE
BRM78_01800	COG2177	Part of the ABC transporter FtsEX involved in
BRM78_01805	COG3437	response regulator, receiver
BRM78_01815	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BRM78_01825	COG1252	NADH dehydrogenase
BRM78_01845	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BRM78_01860	COG4771	TonB-dependent receptor
BRM78_01875	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BRM78_01910	COG3386	PFAM SMP-30 Gluconolaconase
BRM78_01925	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BRM78_01955	COG2353	YceI-like domain
BRM78_02065	COG3039	Transposase
BRM78_02100	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BRM78_02155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BRM78_02160	COG0318	PFAM AMP-dependent synthetase and ligase
BRM78_02170	COG0596	Alpha beta hydrolase
BRM78_02185	COG3177	Filamentation induced by cAMP protein fic
BRM78_02190	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BRM78_02205	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BRM78_02230	COG4191	Histidine kinase
BRM78_02235	COG0028	Belongs to the TPP enzyme family
BRM78_02255	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BRM78_02300	COG5383	Protein conserved in bacteria
BRM78_02315	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BRM78_02320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BRM78_02325	COG1473	amidohydrolase
BRM78_02350	COG3328	transposase activity
BRM78_02365	COG3039	Transposase
BRM78_02535	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BRM78_02550	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
BRM78_02615	COG0358	DNA primase activity
BRM78_02620	COG1295	ribonuclease BN
BRM78_02635	COG1610	YqeY-like protein
BRM78_02640	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BRM78_02650	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BRM78_02690	COG2133	pyrroloquinoline quinone binding
BRM78_02695	COG4682	membrane
BRM78_02730	COG0531	amino acid
BRM78_02770	COG4948	Mandelate Racemase Muconate Lactonizing
BRM78_02780	COG3023	N-Acetylmuramoyl-L-alanine amidase
BRM78_02785	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
BRM78_02820	COG3039	Transposase
BRM78_02875	COG0183	Belongs to the thiolase family
BRM78_02910	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BRM78_02925	COG3104	oligopeptide transport
BRM78_02955	COG1320	monovalent cation:proton antiporter activity
BRM78_02960	COG2212	antiporter activity
BRM78_02970	COG0651	ATP synthesis coupled electron transport
BRM78_02975	COG1006	Multisubunit Na H antiporter MnhC subunit
BRM78_02980	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BRM78_02980	COG2111	Na H antiporter
BRM78_03035	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BRM78_03045	COG0456	acetyltransferase
BRM78_03075	COG4221	oxidoreductase activity
BRM78_03135	COG0697	spore germination
BRM78_03140	COG4305	rare lipoprotein A
BRM78_03145	COG5297	Belongs to the glycosyl hydrolase family 6
BRM78_03155	COG1113	amino acid transport
BRM78_03165	COG0598	Magnesium transport protein CorA
BRM78_03240	COG5297	Belongs to the glycosyl hydrolase family 6
BRM78_03240	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BRM78_03245	COG0659	secondary active sulfate transmembrane transporter activity
BRM78_03290	COG3275	phosphorelay sensor kinase activity
BRM78_03325	COG1505	serine-type exopeptidase activity
BRM78_03370	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BRM78_03400	COG0308	aminopeptidase N
BRM78_03405	COG2199	diguanylate cyclase activity
BRM78_03455	COG1077	Cell shape determining protein MreB Mrl
BRM78_03460	COG1792	Involved in formation and maintenance of cell shape
BRM78_03475	COG0772	Belongs to the SEDS family
BRM78_03520	COG5632	N-Acetylmuramoyl-L-alanine amidase
BRM78_03520	COG1388	LysM domain
BRM78_03520	COG3409	Peptidoglycan-binding domain 1 protein
BRM78_03535	COG2951	lytic endotransglycosylase activity
BRM78_03540	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BRM78_03550	COG1686	Belongs to the peptidase S11 family
BRM78_03600	COG1056	cytidyltransferase-related domain
BRM78_03600	COG1051	belongs to the nudix hydrolase family
BRM78_03635	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BRM78_03640	COG0673	inositol 2-dehydrogenase activity
BRM78_03645	COG2823	Periplasmic or secreted lipoprotein
BRM78_03650	COG4251	negative regulation of phosphorylation
BRM78_03655	COG0784	Response regulator, receiver
BRM78_03660	COG4191	Histidine kinase
BRM78_03665	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BRM78_03715	COG3250	beta-galactosidase activity
BRM78_03740	COG1609	Transcriptional regulator
BRM78_03745	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BRM78_03750	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BRM78_03760	COG1215	transferase activity, transferring glycosyl groups
BRM78_03765	COG1649	PFAM Uncharacterised BCR, COG1649
BRM78_03765	COG0726	polysaccharide deacetylase
BRM78_03815	COG3039	Transposase
BRM78_03870	COG3039	Transposase
BRM78_03885	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BRM78_03890	COG3039	Transposase
BRM78_03945	COG2205	protein histidine kinase activity
BRM78_03985	COG2205	protein histidine kinase activity
BRM78_03990	COG0745	RESPONSE REGULATOR receiver
BRM78_04035	COG0488	(ABC) transporter
BRM78_04075	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BRM78_04075	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BRM78_04105	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BRM78_04130	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BRM78_04135	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BRM78_04145	COG2205	protein histidine kinase activity
BRM78_04150	COG0745	RESPONSE REGULATOR receiver
BRM78_04155	COG0277	FAD linked oxidase domain protein
BRM78_04160	COG1988	membrane-bound metal-dependent
BRM78_04205	COG3116	cell division
BRM78_04220	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BRM78_04225	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BRM78_04245	COG1181	Belongs to the D-alanine--D-alanine ligase family
BRM78_04250	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BRM78_04275	COG1388	LysM domain
BRM78_04275	COG4942	peptidase
BRM78_04290	COG0494	nUDIX hydrolase
BRM78_04305	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BRM78_04320	COG0604	alcohol dehydrogenase
BRM78_04320	COG3321	synthase
BRM78_04320	COG1028	Short-chain dehydrogenase reductase Sdr
BRM78_04375	COG2226	methyltransferase
BRM78_04435	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BRM78_04450	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BRM78_04470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BRM78_04475	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BRM78_04485	COG0667	Aldo Keto reductase
BRM78_04535	COG2175	clavaminate synthase activity
BRM78_04545	COG4181	ATPase activity
BRM78_04560	COG0642	Histidine kinase
BRM78_04585	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BRM78_04645	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BRM78_04660	COG0123	including yeast histone deacetylase and acetoin utilization protein
BRM78_04665	COG2096	Adenosyltransferase
BRM78_04675	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BRM78_04680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BRM78_04720	COG0583	DNA-binding transcription factor activity
BRM78_04725	COG0318	PFAM AMP-dependent synthetase and ligase
BRM78_04735	COG1024	Enoyl-CoA hydratase
BRM78_04755	COG3386	PFAM SMP-30 Gluconolaconase
BRM78_04845	COG0745	RESPONSE REGULATOR receiver
BRM78_04845	COG3706	GGDEF domain
BRM78_04895	COG1902	pentaerythritol trinitrate reductase activity
BRM78_04895	COG0446	pyridine nucleotide-disulphide oxidoreductase
BRM78_04930	COG0156	8-amino-7-oxononanoate synthase activity
BRM78_04935	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BRM78_04940	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BRM78_04945	COG4208	sulfate ABC transporter
BRM78_04950	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BRM78_04985	COG0406	alpha-ribazole phosphatase activity
BRM78_04995	COG0285	dihydrofolate synthase activity
BRM78_05015	COG2833	Protein of unknown function (DUF455)
BRM78_05040	COG0671	phosphoesterase, PA-phosphatase related
BRM78_05045	COG0438	transferase activity, transferring glycosyl groups
BRM78_05055	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BRM78_05070	COG4783	chaperone-mediated protein folding
BRM78_05150	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BRM78_05160	COG0583	DNA-binding transcription factor activity
BRM78_05165	COG3634	alkyl hydroperoxide reductase activity
BRM78_05175	COG2890	protein-(glutamine-N5) methyltransferase activity
BRM78_05220	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BRM78_05220	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BRM78_05235	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BRM78_05255	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BRM78_05260	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BRM78_05290	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BRM78_05300	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BRM78_05335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BRM78_05355	COG0521	Mo-molybdopterin cofactor biosynthetic process
BRM78_05395	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BRM78_05410	COG0012	GTP binding
BRM78_05440	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BRM78_05445	COG0250	Participates in transcription elongation, termination and antitermination
BRM78_05485	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BRM78_05525	COG0089	rRNA binding
BRM78_05550	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BRM78_05555	COG0255	Belongs to the universal ribosomal protein uL29 family
BRM78_05560	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BRM78_05580	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BRM78_05600	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BRM78_05605	COG1841	ribosomal large subunit assembly
BRM78_05615	COG0201	protein transport
BRM78_05620	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BRM78_05635	COG0202	RNA polymerase activity
BRM78_05640	COG0203	ribosomal protein L17
BRM78_05705	COG3551	Protein conserved in bacteria
BRM78_05735	COG2194	sulfuric ester hydrolase activity
BRM78_05745	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BRM78_05750	COG0745	RESPONSE REGULATOR receiver
BRM78_05755	COG0642	Histidine kinase
BRM78_05765	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BRM78_05770	COG2894	cell division
BRM78_05790	COG4585	Histidine kinase
BRM78_05795	COG2197	response regulator
BRM78_05810	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BRM78_05840	COG2963	transposase activity
BRM78_05890	COG3501	Rhs element vgr protein
BRM78_05945	COG3039	Transposase
BRM78_05955	COG3501	Rhs element vgr protein
BRM78_05960	COG3501	Rhs element vgr protein
BRM78_05995	COG3501	Rhs element vgr protein
BRM78_06060	COG3501	Rhs element vgr protein
BRM78_06180	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
BRM78_06200	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BRM78_06205	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
BRM78_06215	COG3039	Transposase
BRM78_06220	COG0732	type I restriction modification DNA specificity domain
BRM78_06225	COG3039	Transposase
BRM78_06250	COG3039	Transposase
BRM78_06255	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BRM78_06290	COG0328	RNA-DNA hybrid ribonuclease activity
BRM78_06290	COG0406	alpha-ribazole phosphatase activity
BRM78_06360	COG1297	OPT oligopeptide transporter protein
BRM78_06365	COG3039	Transposase
BRM78_06390	COG1506	peptidase
BRM78_06390	COG0823	Involved in the tonB-independent uptake of proteins
BRM78_06420	COG2207	Transcriptional regulator
BRM78_06420	COG1917	Cupin 2, conserved barrel domain protein
BRM78_06440	COG3039	Transposase
BRM78_06465	COG0753	catalase activity
BRM78_06510	COG0469	pyruvate kinase activity
BRM78_06515	COG3588	fructose-bisphosphate aldolase
BRM78_06520	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BRM78_06565	COG2198	Histidine kinase
BRM78_06565	COG2205	protein histidine kinase activity
BRM78_06565	COG0784	Response regulator, receiver
BRM78_06595	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BRM78_06605	COG0529	Catalyzes the synthesis of activated sulfate
BRM78_06605	COG2895	sulfate adenylyltransferase (ATP) activity
BRM78_06620	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BRM78_06625	COG0308	aminopeptidase N
BRM78_06655	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BRM78_06680	COG1970	mechanosensitive ion channel activity
BRM78_06710	COG3273	potassium ion transport
BRM78_06710	COG0471	metal ion transport
BRM78_06820	COG3039	Transposase
BRM78_06825	COG3039	Transposase
BRM78_06905	COG3118	belongs to the thioredoxin family
BRM78_06935	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BRM78_06985	COG2968	Membrane
BRM78_06995	COG1530	ribonuclease E activity
BRM78_07000	COG3164	Protein of unknown function
BRM78_07010	COG0312	modulator of DNA gyrase
BRM78_07015	COG3028	Belongs to the UPF0307 family
BRM78_07020	COG0312	modulator of DNA gyrase
BRM78_07045	COG0142	geranyltranstransferase activity
BRM78_07055	COG0037	tRNA processing
BRM78_07060	COG1785	Belongs to the alkaline phosphatase family
BRM78_07065	COG1301	dicarboxylic acid transport
BRM78_07080	COG0791	NLP P60 protein
BRM78_07085	COG0791	NLP P60 protein
BRM78_07090	COG1047	Peptidyl-prolyl cis-trans
BRM78_07095	COG2311	Membrane
BRM78_07100	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BRM78_07145	COG0489	protein tyrosine kinase activity
BRM78_07170	COG0412	Dienelactone hydrolase
BRM78_07180	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BRM78_07235	COG2890	protein-(glutamine-N5) methyltransferase activity
BRM78_07245	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BRM78_07250	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BRM78_07350	COG1028	Short-chain dehydrogenase reductase Sdr
BRM78_07370	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BRM78_07390	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BRM78_07395	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BRM78_07400	COG1034	ATP synthesis coupled electron transport
BRM78_07420	COG0713	ATP synthesis coupled electron transport
BRM78_07435	COG1007	ATP synthesis coupled electron transport
BRM78_07450	COG0195	Participates in both transcription termination and antitermination
BRM78_07470	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BRM78_07505	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BRM78_07510	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BRM78_07520	COG2095	MarC family integral membrane protein
BRM78_07535	COG1611	Belongs to the LOG family
BRM78_07575	COG4969	Belongs to the N-Me-Phe pilin family
BRM78_07615	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BRM78_07620	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BRM78_07625	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BRM78_07640	COG0776	regulation of translation
BRM78_07685	COG0438	transferase activity, transferring glycosyl groups
BRM78_07690	COG0438	transferase activity, transferring glycosyl groups
BRM78_07740	COG3040	lipid binding
BRM78_07830	COG0784	Response regulator, receiver
BRM78_07830	COG4191	Histidine kinase
BRM78_07855	COG0552	protein localization to endoplasmic reticulum
BRM78_07865	COG3938	Belongs to the proline racemase family
BRM78_07870	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BRM78_07885	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BRM78_07895	COG0006	proline dipeptidase activity
BRM78_07910	COG0531	amino acid
BRM78_07960	COG4206	TonB-dependent receptor
BRM78_08065	COG0746	molybdenum cofactor guanylyltransferase activity
BRM78_08090	COG1648	precorrin-2 dehydrogenase activity
BRM78_08090	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BRM78_08120	COG3039	Transposase
BRM78_08125	COG3039	Transposase
BRM78_08165	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BRM78_08185	COG3039	Transposase
BRM78_08210	COG1530	ribonuclease E activity
BRM78_08220	COG3064	Membrane
BRM78_08225	COG0428	transporter
BRM78_08230	COG0428	transporter
BRM78_08240	COG2154	pterin-4-alpha-carbinolamine dehydratase
BRM78_08245	COG0316	Belongs to the HesB IscA family
BRM78_08245	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BRM78_08290	COG3039	Transposase
BRM78_08310	COG3039	Transposase
BRM78_08390	COG3501	Rhs element vgr protein
BRM78_08425	COG0631	protein serine/threonine phosphatase activity
BRM78_08430	COG0515	serine threonine protein kinase
BRM78_08460	COG1858	cytochrome C peroxidase
BRM78_08515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BRM78_08520	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BRM78_08540	COG2201	protein-glutamate methylesterase activity
BRM78_08595	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BRM78_08615	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BRM78_08630	COG1595	DNA-templated transcription, initiation
BRM78_08680	COG2244	polysaccharide biosynthetic process
BRM78_08710	COG2264	protein methyltransferase activity
BRM78_08720	COG0438	transferase activity, transferring glycosyl groups
BRM78_08740	COG1136	(ABC) transporter
BRM78_08745	COG1132	(ABC) transporter
BRM78_08755	COG0477	Major facilitator Superfamily
BRM78_08775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BRM78_08790	COG1253	flavin adenine dinucleotide binding
BRM78_08805	COG0306	phosphate transporter
BRM78_08810	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BRM78_08885	COG2840	Smr protein MutS2
BRM78_08900	COG1238	metal cluster binding
BRM78_08915	COG1534	Rna-binding protein
BRM78_08925	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BRM78_08930	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BRM78_08940	COG1923	regulation of RNA biosynthetic process
BRM78_08945	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BRM78_08950	COG1546	Belongs to the CinA family
BRM78_08975	COG2137	regulation of response to DNA damage stimulus
BRM78_08985	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BRM78_09010	COG0305	Participates in initiation and elongation during chromosome replication
BRM78_09015	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BRM78_09035	COG1741	Belongs to the pirin family
BRM78_09040	COG0583	DNA-binding transcription factor activity
BRM78_09070	COG0351	phosphomethylpyrimidine kinase
BRM78_09080	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BRM78_09085	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BRM78_09100	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BRM78_09110	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BRM78_09115	COG3734	2-keto-3-deoxy-galactonokinase
BRM78_09130	COG0800	Aldolase
BRM78_09145	COG1501	Belongs to the glycosyl hydrolase 31 family
BRM78_09155	COG1070	Carbohydrate kinase
BRM78_09165	COG0477	Major facilitator Superfamily
BRM78_09235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BRM78_09240	COG2258	MOSC domain
BRM78_09250	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BRM78_09255	COG0505	Belongs to the CarA family
BRM78_09265	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BRM78_09270	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BRM78_09280	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BRM78_09355	COG2205	protein histidine kinase activity
BRM78_09355	COG2198	Histidine kinase
BRM78_09355	COG0784	Response regulator, receiver
BRM78_09360	COG1024	Enoyl-CoA hydratase
BRM78_09365	COG0318	PFAM AMP-dependent synthetase and ligase
BRM78_09395	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BRM78_09430	COG0840	transmembrane signaling receptor activity
BRM78_09455	COG0835	chemotaxis
BRM78_09475	COG0840	transmembrane signaling receptor activity
BRM78_09480	COG0840	transmembrane signaling receptor activity
BRM78_09485	COG0840	transmembrane signaling receptor activity
BRM78_09490	COG0840	transmembrane signaling receptor activity
BRM78_09500	COG0840	transmembrane signaling receptor activity
BRM78_09510	COG0840	transmembrane signaling receptor activity
BRM78_09525	COG0840	transmembrane signaling receptor activity
BRM78_09550	COG0745	RESPONSE REGULATOR receiver
BRM78_09560	COG0835	chemotaxis
BRM78_09565	COG1192	Involved in chromosome partitioning
BRM78_09570	COG1360	Flagellar Motor Protein
BRM78_09575	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BRM78_09595	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BRM78_09605	COG4771	TonB-dependent receptor
BRM78_09635	COG3039	Transposase
BRM78_09695	COG3501	Rhs element vgr protein
BRM78_09715	COG3501	Rhs element vgr protein
BRM78_09755	COG3039	Transposase
BRM78_09770	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BRM78_09770	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BRM78_09775	COG1105	Belongs to the carbohydrate kinase PfkB family
BRM78_09780	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BRM78_09780	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BRM78_09785	COG1609	Transcriptional regulator
BRM78_09805	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BRM78_09810	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BRM78_09820	COG2902	Dehydrogenase
BRM78_09830	COG3039	Transposase
BRM78_09840	COG5002	protein histidine kinase activity
BRM78_09840	COG0784	Response regulator, receiver
BRM78_09840	COG2205	protein histidine kinase activity
BRM78_09845	COG2733	membrane
BRM78_09855	COG1121	(ABC) transporter
BRM78_09890	COG0243	molybdopterin cofactor binding
BRM78_09900	COG0477	Major facilitator Superfamily
BRM78_09905	COG3706	GGDEF domain
BRM78_09905	COG0745	RESPONSE REGULATOR receiver
BRM78_09910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BRM78_09915	COG0174	glutamine synthetase
BRM78_09955	COG3842	ATPase activity
BRM78_09960	COG1176	ABC-type spermidine putrescine transport system, permease component I
BRM78_09965	COG1177	transmembrane transport
BRM78_09975	COG1012	belongs to the aldehyde dehydrogenase family
BRM78_09990	COG4535	Mg2 and Co2 transporter CorC
BRM78_10010	COG1702	phosphate starvation-inducible protein PhoH
BRM78_10035	COG0741	lytic transglycosylase activity
BRM78_10045	COG0723	plastoquinol--plastocyanin reductase activity
BRM78_10050	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BRM78_10055	COG2857	Cytochrome c1
BRM78_10060	COG0625	glutathione transferase activity
BRM78_10065	COG2969	positive regulation of protein catabolic process
BRM78_10110	COG3328	transposase activity
BRM78_10195	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BRM78_10220	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BRM78_10225	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BRM78_10225	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BRM78_10230	COG0802	atpase or kinase
BRM78_10235	COG0860	N-Acetylmuramoyl-L-alanine amidase
BRM78_10265	COG1028	Short-chain dehydrogenase reductase Sdr
BRM78_10285	COG2081	HI0933 family
BRM78_10290	COG4681	YaeQ
BRM78_10305	COG0625	glutathione transferase activity
BRM78_10325	COG0513	Belongs to the DEAD box helicase family
BRM78_10360	COG0483	inositol monophosphate 1-phosphatase activity
BRM78_10375	COG5001	Diguanylate cyclase
BRM78_10375	COG3300	MHYT domain
BRM78_10380	COG1509	lysine 2,3-aminomutase activity
BRM78_10395	COG0402	S-adenosylhomocysteine deaminase activity
BRM78_10430	COG4677	pectinesterase activity
BRM78_10445	COG3039	Transposase
BRM78_10485	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BRM78_10495	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BRM78_10510	COG2166	iron-sulfur cluster assembly
BRM78_10525	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BRM78_10530	COG0137	argininosuccinate synthase activity
BRM78_10540	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BRM78_10545	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BRM78_10615	COG1271	oxidase subunit
BRM78_10635	COG4988	ABC transporter
BRM78_10640	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BRM78_10740	COG3039	Transposase
BRM78_10780	COG0643	Histidine kinase
BRM78_10780	COG2198	Histidine kinase
BRM78_10800	COG0455	bacterial-type flagellum organization
BRM78_10810	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BRM78_10825	COG5001	Diguanylate cyclase
BRM78_10825	COG3300	MHYT domain
BRM78_10830	COG3300	MHYT domain
BRM78_10830	COG5001	Diguanylate cyclase
BRM78_10835	COG1684	flagellar biosynthetic protein fliR
BRM78_10840	COG1987	bacterial-type flagellum assembly
BRM78_10855	COG3190	flagellar
BRM78_10905	COG1677	Flagellar hook-basal body complex protein FliE
BRM78_10940	COG1028	Short-chain dehydrogenase reductase Sdr
BRM78_10950	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BRM78_10965	COG2204	response regulator
BRM78_10970	COG2201	protein-glutamate methylesterase activity
BRM78_11000	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BRM78_11005	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BRM78_11035	COG4786	Flagellar basal body rod
BRM78_11045	COG4787	bacterial-type flagellum-dependent cell motility
BRM78_11050	COG1749	Flagellar hook protein flgE
BRM78_11055	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BRM78_11060	COG1558	bacterial-type flagellum-dependent cell motility
BRM78_11070	COG0835	chemotaxis
BRM78_11070	COG0784	Response regulator, receiver
BRM78_11090	COG5002	protein histidine kinase activity
BRM78_11100	COG4585	Histidine kinase
BRM78_11105	COG5001	Diguanylate cyclase
BRM78_11130	COG0482	sulfurtransferase activity
BRM78_11140	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BRM78_11145	COG0542	response to heat
BRM78_11150	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BRM78_11170	COG0492	ferredoxin-NADP+ reductase activity
BRM78_11175	COG1674	ftsk spoiiie
BRM78_11200	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BRM78_11220	COG0038	chloride channel
BRM78_11225	COG0183	Belongs to the thiolase family
BRM78_11230	COG1250	3-hydroxyacyl-CoA dehydrogenase
BRM78_11230	COG1024	Enoyl-CoA hydratase
BRM78_11240	COG0105	UTP biosynthetic process
BRM78_11255	COG1426	Protein conserved in bacteria
BRM78_11265	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BRM78_11275	COG0303	'Molybdopterin
BRM78_11305	COG3039	Transposase
BRM78_11315	COG3039	Transposase
BRM78_11345	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BRM78_11365	COG0742	ribosomal rna small subunit methyltransferase
BRM78_11385	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BRM78_11390	COG0405	Gamma-glutamyltransferase
BRM78_11485	COG1862	Preprotein translocase
BRM78_11495	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BRM78_11530	COG3328	transposase activity
BRM78_11545	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BRM78_11555	COG0704	Plays a role in the regulation of phosphate uptake
BRM78_11570	COG0573	inorganic phosphate transmembrane transporter activity
BRM78_11575	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BRM78_11615	COG3039	Transposase
BRM78_11630	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BRM78_11640	COG1024	Enoyl-CoA hydratase
BRM78_11650	COG0494	nUDIX hydrolase
BRM78_11720	COG0667	Aldo Keto reductase
BRM78_11730	COG2925	Exonuclease
BRM78_11755	COG0288	reversible hydration of carbon dioxide
BRM78_11790	COG0316	Belongs to the HesB IscA family
BRM78_11815	COG3115	cell septum assembly
BRM78_11830	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
BRM78_11870	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BRM78_11880	COG2986	histidine ammonia-lyase
BRM78_11930	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BRM78_11940	COG0077	Prephenate dehydratase
BRM78_11940	COG1605	Chorismate mutase
BRM78_11985	COG4566	intracellular signal transduction
BRM78_12035	COG0860	N-Acetylmuramoyl-L-alanine amidase
BRM78_12050	COG0617	tRNA 3'-terminal CCA addition
BRM78_12100	COG1472	Belongs to the glycosyl hydrolase 3 family
BRM78_12120	COG5001	Diguanylate cyclase
BRM78_12120	COG4251	negative regulation of phosphorylation
BRM78_12120	COG3706	GGDEF domain
BRM78_12120	COG2203	Gaf domain
BRM78_12210	COG0386	Belongs to the glutathione peroxidase family
BRM78_12260	COG3706	GGDEF domain
BRM78_12290	COG0784	Response regulator, receiver
BRM78_12290	COG2205	protein histidine kinase activity
BRM78_12290	COG5002	protein histidine kinase activity
BRM78_12320	COG0800	Aldolase
BRM78_12325	COG0129	dihydroxy-acid dehydratase activity
BRM78_12330	COG0363	glucosamine-6-phosphate deaminase activity
BRM78_12340	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BRM78_12355	COG0354	folic acid binding
BRM78_12370	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BRM78_12385	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BRM78_12400	COG4591	ABC-type transport system involved in lipoprotein release permease component
BRM78_12430	COG0811	peptide transport
BRM78_12455	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BRM78_12500	COG3328	transposase activity
BRM78_12525	COG3039	Transposase
BRM78_12540	COG2801	Transposase and inactivated derivatives
BRM78_12550	COG2201	protein-glutamate methylesterase activity
BRM78_12645	COG3039	Transposase
BRM78_12650	COG3039	Transposase
BRM78_12665	COG1278	Cold shock
BRM78_12675	COG3328	transposase activity
BRM78_12700	COG3039	Transposase
BRM78_12715	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BRM78_12735	COG0557	exoribonuclease II activity
BRM78_12765	COG1960	acyl-CoA dehydrogenase activity
BRM78_12775	COG1410	methionine synthase
BRM78_12775	COG0646	methionine synthase
BRM78_12780	COG1410	methionine synthase
BRM78_12780	COG0646	methionine synthase
BRM78_12790	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BRM78_12830	COG0386	Belongs to the glutathione peroxidase family
BRM78_12840	COG1725	Transcriptional regulator
BRM78_12845	COG1131	(ABC) transporter
BRM78_12925	COG2850	peptidyl-arginine hydroxylation
BRM78_12960	COG1132	(ABC) transporter
BRM78_12975	COG0583	DNA-binding transcription factor activity
BRM78_12995	COG1605	Chorismate mutase
BRM78_12995	COG0287	Prephenate dehydrogenase
BRM78_13000	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BRM78_13030	COG0497	DNA recombination
BRM78_13040	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BRM78_13050	COG2914	Belongs to the UPF0125 (RnfH) family
BRM78_13075	COG1960	acyl-CoA dehydrogenase activity
BRM78_13130	COG2814	Major facilitator Superfamily
BRM78_13135	COG1566	PFAM secretion protein HlyD family protein
BRM78_13175	COG4774	siderophore transport
BRM78_13190	COG0367	asparagine synthase
BRM78_13205	COG1393	Belongs to the ArsC family
BRM78_13225	COG0024	Methionine aminopeptidase
BRM78_13290	COG0575	Belongs to the CDS family
BRM78_13300	COG0750	zinc metalloprotease
BRM78_13355	COG4771	TonB-dependent receptor
BRM78_13360	COG1131	(ABC) transporter
BRM78_13425	COG0529	Catalyzes the synthesis of activated sulfate
BRM78_13425	COG2895	sulfate adenylyltransferase (ATP) activity
BRM78_13460	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BRM78_13475	COG2040	homocysteine
BRM78_13480	COG0833	amino acid
BRM78_13510	COG2878	Part of a membrane complex involved in electron transport
BRM78_13530	COG1595	DNA-templated transcription, initiation
BRM78_13555	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BRM78_13570	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BRM78_13575	COG0251	oxidation-reduction process
BRM78_13585	COG0392	lysyltransferase activity
BRM78_13585	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BRM78_13640	COG2814	Major facilitator Superfamily
BRM78_13645	COG1902	pentaerythritol trinitrate reductase activity
BRM78_13660	COG2824	Alkylphosphonate utilization operon protein PhnA
BRM78_13675	COG1047	Peptidyl-prolyl cis-trans
BRM78_13720	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BRM78_13735	COG1451	nucleotide metabolic process
BRM78_13760	COG0183	Belongs to the thiolase family
BRM78_13775	COG0745	RESPONSE REGULATOR receiver
BRM78_13775	COG3706	GGDEF domain
BRM78_13790	COG1793	dna ligase
BRM78_13790	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BRM78_13800	COG1793	dna ligase
BRM78_13805	COG1201	RNA secondary structure unwinding
BRM78_13825	COG1278	Cold shock
BRM78_13830	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BRM78_13845	COG3046	protein related to deoxyribodipyrimidine photolyase
BRM78_13850	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
BRM78_13855	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BRM78_13915	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BRM78_13930	COG1250	3-hydroxyacyl-CoA dehydrogenase
BRM78_13930	COG1024	Enoyl-CoA hydratase
BRM78_13950	COG1024	Enoyl-CoA hydratase
BRM78_13955	COG1960	acyl-CoA dehydrogenase activity
BRM78_14025	COG2353	YceI-like domain
BRM78_14035	COG2353	YceI-like domain
BRM78_14050	COG1760	l-serine dehydratase
BRM78_14060	COG0626	cystathionine gamma-synthase activity
BRM78_14065	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BRM78_14070	COG0739	heme binding
BRM78_14080	COG1272	protein, Hemolysin III
BRM78_14100	COG0463	Glycosyl transferase, family 2
BRM78_14110	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BRM78_14120	COG4771	TonB-dependent receptor
BRM78_14125	COG1309	transcriptional regulator
BRM78_14135	COG1960	acyl-CoA dehydrogenase activity
BRM78_14185	COG0330	HflC and HflK could
BRM78_14200	COG3956	TIGRFAM MazG family protein
BRM78_14210	COG0494	nUDIX hydrolase
BRM78_14220	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BRM78_14225	COG0837	glucose binding
BRM78_14240	COG1388	LysM domain
BRM78_14240	COG3858	chitin binding
BRM78_14260	COG1472	Belongs to the glycosyl hydrolase 3 family
BRM78_14290	COG3039	Transposase
BRM78_14340	COG3537	Alpha-1,2-mannosidase
BRM78_14400	COG3142	Participates in the control of copper homeostasis
BRM78_14405	COG1446	asparaginase
BRM78_14455	COG0840	transmembrane signaling receptor activity
BRM78_14460	COG0835	chemotaxis
BRM78_14475	COG0189	ligase activity
BRM78_14485	COG1397	ADP-ribosylglycohydrolase
BRM78_14495	COG1199	ATP-dependent helicase activity
BRM78_14505	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BRM78_14520	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BRM78_14575	COG1643	Atp-dependent helicase
BRM78_14580	COG0783	Belongs to the Dps family
BRM78_14590	COG0514	ATP-dependent DNA helicase (RecQ)
BRM78_14675	COG1187	pseudouridine synthase activity
BRM78_14685	COG0602	queuosine metabolic process
BRM78_14695	COG2885	chlorophyll binding
BRM78_14710	COG0848	biopolymer transport protein
BRM78_14720	COG0824	Thioesterase
BRM78_14855	COG3209	COG3209 Rhs family protein
BRM78_14855	COG3209	COG3209 Rhs family protein
BRM78_14865	COG3501	Rhs element vgr protein
BRM78_14875	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BRM78_14880	COG1845	cytochrome c oxidase, subunit III
BRM78_14885	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BRM78_14915	COG0196	riboflavin kinase activity
BRM78_14920	COG0728	peptidoglycan biosynthetic process
BRM78_14925	COG0268	Binds directly to 16S ribosomal RNA
BRM78_14945	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BRM78_14950	COG0824	Thioesterase
BRM78_14965	COG1946	Acyl-CoA thioesterase
BRM78_14975	COG1595	DNA-templated transcription, initiation
BRM78_15035	COG1877	trehalose-phosphatase activity
BRM78_15040	COG3387	PFAM Glycoside hydrolase 15-related
BRM78_15065	COG0564	pseudouridine synthase activity
BRM78_15070	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BRM78_15075	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BRM78_15075	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BRM78_15090	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BRM78_15135	COG2194	sulfuric ester hydrolase activity
BRM78_15140	COG4969	Belongs to the N-Me-Phe pilin family
BRM78_15150	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BRM78_15195	COG3039	Transposase
BRM78_15210	COG3039	Transposase
BRM78_15235	COG1132	(ABC) transporter
BRM78_15265	COG0745	RESPONSE REGULATOR receiver
BRM78_15270	COG5000	phosphorelay sensor kinase activity
BRM78_15270	COG5002	protein histidine kinase activity
BRM78_15275	COG0475	glutathione-regulated potassium exporter activity
BRM78_15310	COG1187	pseudouridine synthase activity
BRM78_15315	COG5002	protein histidine kinase activity
BRM78_15315	COG5001	Diguanylate cyclase
BRM78_15375	COG3039	Transposase
BRM78_15420	COG1028	Short-chain dehydrogenase reductase Sdr
BRM78_15440	COG0415	Belongs to the DNA photolyase family
BRM78_15445	COG0305	Participates in initiation and elongation during chromosome replication
BRM78_15455	COG0367	asparagine synthase
BRM78_15470	COG1960	acyl-CoA dehydrogenase activity
BRM78_15485	COG0084	hydrolase, TatD family'
BRM78_15490	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BRM78_15555	COG0735	belongs to the Fur family
BRM78_15595	COG3039	Transposase
BRM78_15620	COG3039	Transposase
BRM78_15645	COG2205	protein histidine kinase activity
BRM78_15665	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BRM78_15675	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BRM78_15685	COG0643	Histidine kinase
BRM78_15685	COG2198	Histidine kinase
BRM78_15690	COG0840	transmembrane signaling receptor activity
BRM78_15695	COG0835	chemotaxis
BRM78_15700	COG2202	Pas domain
BRM78_15700	COG2200	EAL domain
BRM78_15700	COG2199	diguanylate cyclase activity
BRM78_15705	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BRM78_15720	COG3590	peptidase
BRM78_15740	COG1515	deoxyribonuclease V activity
BRM78_15750	COG1741	Belongs to the pirin family
BRM78_15805	COG3501	Rhs element vgr protein
BRM78_15835	COG3501	Rhs element vgr protein
BRM78_15855	COG3501	Rhs element vgr protein
BRM78_15865	COG1741	Belongs to the pirin family
BRM78_15870	COG1966	Carbon starvation protein
BRM78_15875	COG2879	small protein
BRM78_15915	COG3706	GGDEF domain
BRM78_15915	COG4251	negative regulation of phosphorylation
BRM78_15915	COG5001	Diguanylate cyclase
BRM78_15915	COG2203	Gaf domain
BRM78_15925	COG0629	single-stranded DNA binding
BRM78_15930	COG0142	geranyltranstransferase activity
BRM78_15960	COG0527	aspartate kinase activity
BRM78_15970	COG0384	phenazine biosynthesis protein PhzF
BRM78_15980	COG1764	response to oxidative stress
BRM78_16010	COG0519	Catalyzes the synthesis of GMP from XMP
BRM78_16045	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BRM78_16090	COG0693	protein deglycase activity
BRM78_16110	COG1959	2 iron, 2 sulfur cluster binding
BRM78_16115	COG0719	Fe-S assembly protein
BRM78_16120	COG0396	ATPase activity
BRM78_16125	COG0719	Fe-S assembly protein
BRM78_16130	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BRM78_16185	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BRM78_16195	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BRM78_16200	COG0174	glutamine synthetase
BRM78_16205	COG3328	transposase activity
BRM78_16240	COG2207	Transcriptional regulator
BRM78_16260	COG0657	acetylesterase activity
BRM78_16260	COG2755	lipolytic protein G-D-S-L family
BRM78_16285	COG0488	(ABC) transporter
BRM78_16320	COG4651	solute:proton antiporter activity
BRM78_16320	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BRM78_16335	COG4772	TonB-dependent receptor
BRM78_16345	COG4264	IucA IucC family
BRM78_16350	COG2814	Major facilitator Superfamily
BRM78_16360	COG0019	diaminopimelate decarboxylase activity
BRM78_16420	COG4206	TonB-dependent receptor
BRM78_16460	COG0542	response to heat
BRM78_16500	COG0534	Mate efflux family protein
BRM78_16550	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BRM78_16560	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BRM78_16610	COG1555	photosystem II stabilization
BRM78_16615	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BRM78_16630	COG3178	'Phosphotransferase
BRM78_16635	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BRM78_16645	COG0628	permease
BRM78_16670	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BRM78_16700	COG0271	Belongs to the BolA IbaG family
BRM78_16710	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BRM78_16720	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BRM78_16725	COG1137	ATPase activity
BRM78_16740	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BRM78_16760	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BRM78_16765	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BRM78_16775	COG2239	Acts as a magnesium transporter
BRM78_16785	COG1294	oxidase, subunit
BRM78_16790	COG1271	oxidase subunit
BRM78_16810	COG1113	amino acid transport
BRM78_16825	COG2197	response regulator
BRM78_16830	COG0531	amino acid
BRM78_16885	COG0789	Transcriptional regulator
BRM78_16900	COG0754	glutathionylspermidine amidase activity
BRM78_16925	COG1842	Phage shock protein A
BRM78_17085	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BRM78_17090	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BRM78_17130	COG0745	RESPONSE REGULATOR receiver
BRM78_17135	COG2205	protein histidine kinase activity
BRM78_17155	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BRM78_17190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BRM78_17190	COG3453	Protein conserved in bacteria
BRM78_17195	COG0725	ABC transporter, periplasmic molybdate-binding protein
BRM78_17200	COG4149	molybdate abc transporter
BRM78_17205	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BRM78_17225	COG0642	Histidine kinase
BRM78_17230	COG0745	RESPONSE REGULATOR receiver
BRM78_17240	COG1028	Short-chain dehydrogenase reductase Sdr
BRM78_17250	COG1022	Amp-dependent synthetase and ligase
BRM78_17275	COG1376	ErfK ybiS ycfS ynhG family protein
BRM78_17280	COG0739	heme binding
BRM78_17290	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BRM78_17295	COG1301	dicarboxylic acid transport
BRM78_17315	COG2304	oxidoreductase activity
BRM78_17335	COG0714	Associated with various cellular activities
BRM78_17385	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BRM78_17400	COG0254	rRNA binding
BRM78_17410	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BRM78_17420	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BRM78_17445	COG1561	YicC-like family, N-terminal region
BRM78_17465	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BRM78_17500	COG0006	proline dipeptidase activity
BRM78_17525	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BRM78_17545	COG2912	Transglutaminase-like superfamily
BRM78_17550	COG1773	rubredoxin
BRM78_17555	COG0352	thiamine-phosphate diphosphorylase activity
BRM78_17590	COG0281	malic enzyme
BRM78_17590	COG0280	phosphate acetyltransferase
BRM78_17610	COG4191	Histidine kinase
BRM78_17625	COG0583	DNA-binding transcription factor activity
BRM78_17645	COG2197	response regulator
BRM78_17650	COG1840	ABC-type Fe3 transport system, periplasmic component
BRM78_17655	COG0642	Histidine kinase
BRM78_17675	COG2851	Citrate transporter
BRM78_17680	COG1028	Short-chain dehydrogenase reductase Sdr
BRM78_17685	COG1609	Transcriptional regulator
BRM78_17695	COG2211	Major facilitator Superfamily
BRM78_17745	COG0726	polysaccharide deacetylase
BRM78_17750	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BRM78_17780	COG3039	Transposase
BRM78_17830	COG0242	peptide deformylase activity
BRM78_17850	COG0714	Associated with various cellular activities
BRM78_17870	COG0537	adenosine 5'-monophosphoramidase activity
BRM78_17900	COG0314	molybdopterin synthase activity
BRM78_17905	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BRM78_17920	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BRM78_17925	COG1234	tRNA 3'-trailer cleavage
BRM78_17935	COG0859	PFAM glycosyl transferase family 9
BRM78_17945	COG0582	viral genome integration into host DNA
BRM78_18005	COG3501	Rhs element vgr protein
BRM78_18030	COG0631	protein serine/threonine phosphatase activity
BRM78_18040	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BRM78_18065	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BRM78_18100	COG0740	serine-type endopeptidase activity
BRM78_18105	COG0544	peptidyl-prolyl cis-trans isomerase activity
BRM78_18160	COG0473	3-isopropylmalate dehydrogenase activity
BRM78_18185	COG0584	glycerophosphoryl diester phosphodiesterase
BRM78_18210	COG3039	Transposase
BRM78_18345	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BRM78_18370	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BRM78_18380	COG0625	glutathione transferase activity
BRM78_18400	COG3781	membrane
BRM78_18410	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BRM78_18440	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BRM78_18460	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BRM78_18485	COG3710	Transcriptional regulator
BRM78_18565	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BRM78_18570	COG1538	Outer membrane efflux protein
BRM78_18575	COG1519	Transferase
BRM78_18580	COG1560	Kdo2-lipid A biosynthetic process
BRM78_18630	COG0308	aminopeptidase N
BRM78_18645	COG0330	HflC and HflK could
BRM78_18650	COG0330	HflC and HflK could
BRM78_18670	COG0678	peroxiredoxin activity
BRM78_18680	COG2826	transposase and inactivated derivatives, IS30 family
BRM78_18740	COG3039	Transposase
BRM78_18775	COG3829	transcription factor binding
BRM78_18810	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BRM78_18815	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BRM78_18830	COG1028	Short-chain dehydrogenase reductase Sdr
BRM78_18855	COG1399	metal-binding, possibly nucleic acid-binding protein
BRM78_18900	COG1518	maintenance of DNA repeat elements
BRM78_18905	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BRM78_18960	COG2188	Transcriptional regulator
BRM78_18975	COG1450	Type ii and iii secretion system protein
BRM78_18990	COG3166	PFAM Fimbrial assembly family protein
BRM78_18995	COG3156	type II secretion system protein K
BRM78_19000	COG4795	General secretion pathway protein
BRM78_19005	COG2165	general secretion pathway protein
BRM78_19010	COG4970	Tfp pilus assembly protein FimT
BRM78_19015	COG2165	general secretion pathway protein
BRM78_19020	COG1459	type II secretion system
BRM78_19030	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BRM78_19050	COG5295	Hep Hag repeat protein
BRM78_19060	COG0047	phosphoribosylformylglycinamidine synthase activity
BRM78_19060	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BRM78_19065	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BRM78_19070	COG4974	Belongs to the 'phage' integrase family
BRM78_19085	COG3039	Transposase
BRM78_19095	COG0795	lipopolysaccharide-transporting ATPase activity
BRM78_19120	COG0525	valine-tRNA ligase activity
BRM78_19190	COG3039	Transposase
BRM78_19215	COG1183	phosphatidylcholine synthase activity
BRM78_19240	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BRM78_19245	COG1127	ABC transporter
BRM78_19250	COG3218	ABC-type transport auxiliary lipoprotein component
BRM78_19250	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BRM78_19290	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BRM78_19295	COG0662	Cupin 2, conserved barrel domain protein
BRM78_19295	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BRM78_19320	COG2086	electron transfer activity
BRM78_19345	COG3328	transposase activity
BRM78_19395	COG0626	cystathionine gamma-synthase activity
BRM78_19440	COG0513	Belongs to the DEAD box helicase family
BRM78_19450	COG0720	synthase
BRM78_19465	COG1956	GAF domain-containing protein
BRM78_19505	COG0339	signal peptide processing
BRM78_19530	COG3039	Transposase
BRM78_19565	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BRM78_19570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BRM78_19660	COG0356	it plays a direct role in the translocation of protons across the membrane
BRM78_19680	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BRM78_19690	COG0508	dehydrogenase complex catalyzes the overall conversion of
BRM78_19720	COG2011	ABC-type metal ion transport system permease component
BRM78_19730	COG0697	spore germination
BRM78_19765	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BRM78_19770	COG1187	pseudouridine synthase activity
BRM78_19775	COG2813	Specifically methylates the guanine in position
BRM78_19810	COG2202	Pas domain
BRM78_19810	COG2205	protein histidine kinase activity
BRM78_19835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BRM78_19840	COG1522	sequence-specific DNA binding
BRM78_19885	COG0745	RESPONSE REGULATOR receiver
BRM78_19900	COG1404	Belongs to the peptidase S8 family
BRM78_19915	COG0842	Transport permease protein
BRM78_19920	COG1131	(ABC) transporter
BRM78_19925	COG0025	NhaP-type Na H and K H
BRM78_19940	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
BRM78_19950	COG1573	uracil-dna glycosylase
BRM78_19960	COG3384	dioxygenase
BRM78_19975	COG0667	Aldo Keto reductase
BRM78_19990	COG3590	peptidase
BRM78_20010	COG0531	amino acid
BRM78_20025	COG2972	Histidine kinase
BRM78_20055	COG2204	response regulator
BRM78_20070	COG1271	oxidase subunit
BRM78_20075	COG1294	oxidase, subunit
BRM78_20230	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BRM78_20240	COG1560	Kdo2-lipid A biosynthetic process
BRM78_20290	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BRM78_20290	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BRM78_20300	COG0242	peptide deformylase activity
BRM78_20305	COG1652	LysM domain
BRM78_20310	COG0758	DNA mediated transformation
BRM78_20330	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BRM78_20330	COG1754	DNA topoisomerase type I activity
BRM78_20350	COG1028	Short-chain dehydrogenase reductase Sdr
BRM78_20360	COG0616	signal peptide processing
BRM78_20365	COG0534	Mate efflux family protein
BRM78_20390	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BRM78_20425	COG1324	tolerance protein
BRM78_20450	COG0511	ligase activity, forming carbon-carbon bonds
BRM78_20460	COG0439	Biotin carboxylase
BRM78_20520	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BRM78_20535	COG0671	phosphoesterase, PA-phosphatase related
BRM78_20535	COG2453	phosphatase
BRM78_20540	COG2267	carboxylic ester hydrolase activity
BRM78_20550	COG2267	carboxylic ester hydrolase activity
BRM78_20565	COG0419	ATPase involved in DNA repair
BRM78_20575	COG0151	Belongs to the GarS family
BRM78_20580	COG0577	efflux transmembrane transporter activity
BRM78_20580	COG1136	(ABC) transporter
BRM78_20590	COG1289	transmembrane transporter activity
BRM78_20605	COG2814	Major facilitator Superfamily
BRM78_20630	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BRM78_20710	COG0739	heme binding
BRM78_20725	COG2211	Major facilitator Superfamily
BRM78_20730	COG0708	Exodeoxyribonuclease III
BRM78_20745	COG1192	Involved in chromosome partitioning
BRM78_20750	COG1475	DNA binding
BRM78_20765	COG0463	Glycosyl transferase, family 2
BRM78_20790	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BRM78_20795	COG2003	Belongs to the UPF0758 family
BRM78_20815	COG4221	oxidoreductase activity
BRM78_20845	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BRM78_20850	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BRM78_20865	COG3485	protocatechuate 3,4-dioxygenase
BRM78_20870	COG3485	protocatechuate 3,4-dioxygenase
BRM78_20905	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BRM78_20915	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BRM78_20925	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BRM78_20925	COG1042	CoA-binding domain protein
BRM78_20925	COG0045	succinate-CoA ligase (ADP-forming) activity
BRM78_20935	COG2239	Acts as a magnesium transporter
BRM78_20955	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BRM78_20960	COG3387	PFAM Glycoside hydrolase 15-related
BRM78_20975	COG3100	YcgL domain-containing protein
BRM78_20980	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BRM78_20990	COG0463	Glycosyl transferase, family 2
BRM78_21005	COG1028	Short-chain dehydrogenase reductase Sdr
BRM78_21030	COG1040	competence protein
BRM78_21050	COG0628	permease
BRM78_21060	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BRM78_21070	COG1595	DNA-templated transcription, initiation
BRM78_21075	COG0753	catalase activity
BRM78_21120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BRM78_21125	COG0180	Tryptophanyl-tRNA synthetase
BRM78_21130	COG3237	CsbD-like
BRM78_21190	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BRM78_21190	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BRM78_21215	COG2205	protein histidine kinase activity
BRM78_21220	COG0745	RESPONSE REGULATOR receiver
BRM78_21230	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BRM78_21260	COG1566	PFAM secretion protein HlyD family protein
BRM78_21280	COG1199	ATP-dependent helicase activity
BRM78_21315	COG0583	DNA-binding transcription factor activity
BRM78_21365	COG0625	glutathione transferase activity
BRM78_21405	COG4555	ABC transporter
BRM78_21415	COG1476	TRANSCRIPTIONal
BRM78_21435	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BRM78_21440	COG1131	(ABC) transporter
BRM78_21445	COG0842	Transport permease protein
BRM78_21455	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BRM78_21565	COG0564	pseudouridine synthase activity
BRM78_21595	COG0339	signal peptide processing
BRM78_21625	COG3254	rhamnose metabolic process
BRM78_21630	COG0738	Major facilitator superfamily
BRM78_21635	COG1414	Transcriptional regulator
BRM78_21645	COG2205	protein histidine kinase activity
BRM78_21660	COG3459	Glycosyltransferase 36 associated
BRM78_21665	COG2211	Major facilitator Superfamily
BRM78_21670	COG3265	gluconokinase activity
BRM78_21685	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BRM78_21735	COG3039	Transposase
BRM78_21770	COG1127	ABC transporter
BRM78_21775	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BRM78_21780	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BRM78_21795	COG2853	Lipoprotein
BRM78_21885	COG0676	glucose-6-phosphate 1-epimerase activity
BRM78_21890	COG3039	Transposase
BRM78_21915	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BRM78_21925	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BRM78_21935	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BRM78_21945	COG1064	alcohol dehydrogenase
BRM78_21990	COG1522	sequence-specific DNA binding
BRM78_21995	COG3186	Phenylalanine-4-hydroxylase
BRM78_22010	COG2755	lipolytic protein G-D-S-L family
BRM78_22040	COG2937	Belongs to the GPAT DAPAT family
BRM78_22080	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BRM78_22100	COG0210	DNA helicase
BRM78_22115	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
BRM78_22140	COG1028	Short-chain dehydrogenase reductase Sdr
BRM78_22220	COG3501	Rhs element vgr protein
BRM78_22230	COG1166	arginine decarboxylase activity
BRM78_22280	COG0606	chelatase, subunit chli
BRM78_22335	COG0366	Alpha amylase catalytic
BRM78_22340	COG0366	Alpha amylase catalytic
BRM78_22375	COG1609	Transcriptional regulator
BRM78_22415	COG0493	'glutamate synthase
BRM78_22420	COG0070	glutamate synthase
BRM78_22420	COG0067	glutamate synthase
BRM78_22420	COG0069	glutamate synthase activity
BRM78_22485	COG1111	helicase
BRM78_22485	COG1205	dead DEAH box helicase
BRM78_22490	COG1272	protein, Hemolysin III
BRM78_22535	COG1136	(ABC) transporter
BRM78_22600	COG2826	transposase and inactivated derivatives, IS30 family
BRM78_22625	COG3039	Transposase
BRM78_22635	COG1090	epimerase
BRM78_22645	COG0642	Histidine kinase
BRM78_22655	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BRM78_22690	COG3039	Transposase
BRM78_22700	COG3039	Transposase
BRM78_22780	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BRM78_22860	COG3264	Mechanosensitive ion channel
BRM78_22860	COG1511	domain protein
BRM78_22875	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BRM78_22885	COG2354	Protein conserved in bacteria
BRM78_22895	COG3706	GGDEF domain
BRM78_22895	COG0745	RESPONSE REGULATOR receiver
BRM78_22910	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BRM78_22935	COG0702	epimerase
BRM78_22945	COG1858	cytochrome C peroxidase
BRM78_23050	COG0513	Belongs to the DEAD box helicase family
BRM78_23060	COG3039	Transposase
BRM78_23110	COG1136	(ABC) transporter
BRM78_23115	COG3039	Transposase
BRM78_23125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BRM78_23150	COG1755	Isoprenylcysteine carboxyl methyltransferase
BRM78_23160	COG3039	Transposase
BRM78_23175	COG4772	TonB-dependent receptor
BRM78_23195	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BRM78_23235	COG0501	Belongs to the peptidase M48B family
BRM78_23245	COG0187	DNA topoisomerase II activity