locus-tag	class	description
C0L89_00025	COG0187	DNA topoisomerase II activity
C0L89_00035	COG0501	Belongs to the peptidase M48B family
C0L89_00065	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
C0L89_00095	COG3039	Transposase
C0L89_00135	COG0793	Belongs to the peptidase S41A family
C0L89_00140	COG4942	peptidase
C0L89_00150	COG2234	aminopeptidase activity
C0L89_00160	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
C0L89_00175	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
C0L89_00185	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
C0L89_00195	COG1064	alcohol dehydrogenase
C0L89_00225	COG0493	'glutamate synthase
C0L89_00230	COG0067	glutamate synthase
C0L89_00230	COG0069	glutamate synthase activity
C0L89_00230	COG0070	glutamate synthase
C0L89_00300	COG1205	dead DEAH box helicase
C0L89_00300	COG1111	helicase
C0L89_00305	COG1272	protein, Hemolysin III
C0L89_00335	COG2032	superoxide dismutase activity
C0L89_00340	COG2204	response regulator
C0L89_00345	COG3852	Histidine kinase
C0L89_00350	COG0004	ammonium transporteR
C0L89_00355	COG0347	Belongs to the P(II) protein family
C0L89_00360	COG0174	glutamine synthetase
C0L89_00415	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C0L89_00425	COG2062	phosphohistidine phosphatase, SixA
C0L89_00430	COG0489	protein tyrosine kinase activity
C0L89_00450	COG1396	sequence-specific DNA binding
C0L89_00455	COG3550	peptidyl-serine autophosphorylation
C0L89_00460	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
C0L89_00465	COG1262	PFAM Formylglycine-generating sulfatase enzyme
C0L89_00480	COG1125	glycine betaine transport
C0L89_00480	COG0517	IMP dehydrogenase activity
C0L89_00495	COG1119	ATPase activity
C0L89_00510	COG1752	Esterase of the alpha-beta hydrolase superfamily
C0L89_00520	COG1522	sequence-specific DNA binding
C0L89_00525	COG3186	Phenylalanine-4-hydroxylase
C0L89_00555	COG1609	Transcriptional regulator
C0L89_00595	COG0366	Alpha amylase catalytic
C0L89_00600	COG0366	Alpha amylase catalytic
C0L89_00610	COG3039	Transposase
C0L89_00620	COG0183	Belongs to the thiolase family
C0L89_00660	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C0L89_00665	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
C0L89_00680	COG0028	Belongs to the TPP enzyme family
C0L89_00685	COG4191	Histidine kinase
C0L89_00710	COG3039	Transposase
C0L89_00720	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C0L89_00735	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C0L89_00740	COG3177	Filamentation induced by cAMP protein fic
C0L89_00745	COG0596	Alpha beta hydrolase
C0L89_00760	COG0318	PFAM AMP-dependent synthetase and ligase
C0L89_00765	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C0L89_00780	COG1181	Belongs to the D-alanine--D-alanine ligase family
C0L89_00810	COG0564	pseudouridine synthase activity
C0L89_00840	COG0339	signal peptide processing
C0L89_00895	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C0L89_00900	COG1960	acyl-CoA dehydrogenase activity
C0L89_00945	COG0523	cobalamin synthesis protein
C0L89_00955	COG0697	spore germination
C0L89_00965	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
C0L89_00970	COG1846	Transcriptional regulator
C0L89_00975	COG1764	response to oxidative stress
C0L89_01000	COG3501	Rhs element vgr protein
C0L89_01025	COG0656	L-ascorbic acid biosynthetic process
C0L89_01040	COG2130	NADP-dependent
C0L89_01055	COG1187	pseudouridine synthase activity
C0L89_01070	COG1643	Atp-dependent helicase
C0L89_01080	COG4807	Protein conserved in bacteria
C0L89_01085	COG2072	flavoprotein involved in K transport
C0L89_01105	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C0L89_01110	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C0L89_01150	COG3039	Transposase
C0L89_01195	COG0084	hydrolase, TatD family'
C0L89_01215	COG0583	DNA-binding transcription factor activity
C0L89_01220	COG2814	Major facilitator Superfamily
C0L89_01230	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C0L89_01235	COG1902	pentaerythritol trinitrate reductase activity
C0L89_01265	COG0745	RESPONSE REGULATOR receiver
C0L89_01285	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C0L89_01290	COG0583	DNA-binding transcription factor activity
C0L89_01320	COG0702	epimerase
C0L89_01325	COG1733	regulation of RNA biosynthetic process
C0L89_01360	COG3039	Transposase
C0L89_01380	COG3501	Rhs element vgr protein
C0L89_01405	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C0L89_01475	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C0L89_01490	COG3485	protocatechuate 3,4-dioxygenase
C0L89_01495	COG3485	protocatechuate 3,4-dioxygenase
C0L89_01510	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C0L89_01515	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C0L89_01530	COG1414	Transcriptional regulator
C0L89_01620	COG1040	competence protein
C0L89_01625	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
C0L89_01730	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C0L89_01805	COG3264	Mechanosensitive ion channel
C0L89_01805	COG1511	domain protein
C0L89_01815	COG3039	Transposase
C0L89_01820	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C0L89_01830	COG2354	Protein conserved in bacteria
C0L89_01840	COG0745	RESPONSE REGULATOR receiver
C0L89_01840	COG3706	GGDEF domain
C0L89_01855	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
C0L89_01880	COG0702	epimerase
C0L89_01890	COG1028	Short-chain dehydrogenase reductase Sdr
C0L89_01920	COG0513	Belongs to the DEAD box helicase family
C0L89_01930	COG3039	Transposase
C0L89_01960	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C0L89_01975	COG3104	oligopeptide transport
C0L89_02005	COG1320	monovalent cation:proton antiporter activity
C0L89_02010	COG2212	antiporter activity
C0L89_02020	COG0651	ATP synthesis coupled electron transport
C0L89_02025	COG1006	Multisubunit Na H antiporter MnhC subunit
C0L89_02030	COG2111	Na H antiporter
C0L89_02030	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C0L89_02065	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
C0L89_02075	COG0456	acetyltransferase
C0L89_02120	COG0134	indole-3-glycerol-phosphate synthase activity
C0L89_02130	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C0L89_02175	COG2906	2 iron, 2 sulfur cluster binding
C0L89_02225	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
C0L89_02245	COG2814	Major facilitator Superfamily
C0L89_02255	COG2814	Major facilitator Superfamily
C0L89_02260	COG1289	transmembrane transporter activity
C0L89_02270	COG0151	Belongs to the GarS family
C0L89_02280	COG0419	ATPase involved in DNA repair
C0L89_02285	COG0138	bifunctional purine biosynthesis protein purh
C0L89_02290	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C0L89_02300	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
C0L89_02355	COG0439	Biotin carboxylase
C0L89_02365	COG0511	ligase activity, forming carbon-carbon bonds
C0L89_02385	COG1324	tolerance protein
C0L89_02405	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C0L89_02425	COG0534	Mate efflux family protein
C0L89_02430	COG0616	signal peptide processing
C0L89_02440	COG1028	Short-chain dehydrogenase reductase Sdr
C0L89_02460	COG1754	DNA topoisomerase type I activity
C0L89_02460	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C0L89_02480	COG0758	DNA mediated transformation
C0L89_02485	COG1652	LysM domain
C0L89_02490	COG0242	peptide deformylase activity
C0L89_02500	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C0L89_02500	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C0L89_02550	COG1560	Kdo2-lipid A biosynthetic process
C0L89_02560	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C0L89_02730	COG3179	chitinase
C0L89_02775	COG4695	Portal protein
C0L89_02800	COG3501	Rhs element vgr protein
C0L89_02855	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C0L89_02860	COG3118	belongs to the thioredoxin family
C0L89_02870	COG2884	Cell division ATP-binding protein ftsE
C0L89_02875	COG2177	Part of the ABC transporter FtsEX involved in
C0L89_02880	COG3437	response regulator, receiver
C0L89_02890	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C0L89_02895	COG2860	membrane
C0L89_02900	COG1252	NADH dehydrogenase
C0L89_02920	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
C0L89_02940	COG3039	Transposase
C0L89_02955	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C0L89_02985	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C0L89_03020	COG2353	YceI-like domain
C0L89_03075	COG3501	Rhs element vgr protein
C0L89_03130	COG4221	oxidoreductase activity
C0L89_03185	COG0697	spore germination
C0L89_03190	COG4305	rare lipoprotein A
C0L89_03195	COG5297	Belongs to the glycosyl hydrolase family 6
C0L89_03205	COG1113	amino acid transport
C0L89_03215	COG0598	Magnesium transport protein CorA
C0L89_03290	COG5001	Diguanylate cyclase
C0L89_03290	COG3300	MHYT domain
C0L89_03315	COG5297	Belongs to the glycosyl hydrolase family 6
C0L89_03315	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
C0L89_03320	COG0659	secondary active sulfate transmembrane transporter activity
C0L89_03325	COG3706	GGDEF domain
C0L89_03355	COG3275	phosphorelay sensor kinase activity
C0L89_03390	COG1505	serine-type exopeptidase activity
C0L89_03410	COG2832	Protein of unknown function (DUF454)
C0L89_03430	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
C0L89_03440	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
C0L89_03475	COG5001	Diguanylate cyclase
C0L89_03475	COG3300	MHYT domain
C0L89_03480	COG0308	aminopeptidase N
C0L89_03500	COG1077	Cell shape determining protein MreB Mrl
C0L89_03505	COG1792	Involved in formation and maintenance of cell shape
C0L89_03520	COG0772	Belongs to the SEDS family
C0L89_03545	COG2951	lytic endotransglycosylase activity
C0L89_03550	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C0L89_03555	COG1686	Belongs to the peptidase S11 family
C0L89_03595	COG1051	belongs to the nudix hydrolase family
C0L89_03595	COG1056	cytidyltransferase-related domain
C0L89_03630	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
C0L89_03635	COG0673	inositol 2-dehydrogenase activity
C0L89_03640	COG2823	Periplasmic or secreted lipoprotein
C0L89_03645	COG4251	negative regulation of phosphorylation
C0L89_03650	COG0784	Response regulator, receiver
C0L89_03655	COG4191	Histidine kinase
C0L89_03660	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C0L89_03685	COG3039	Transposase
C0L89_03700	COG3250	beta-galactosidase activity
C0L89_03725	COG1609	Transcriptional regulator
C0L89_03730	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C0L89_03735	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C0L89_03750	COG1215	transferase activity, transferring glycosyl groups
C0L89_03755	COG1649	PFAM Uncharacterised BCR, COG1649
C0L89_03755	COG0726	polysaccharide deacetylase
C0L89_03775	COG3039	Transposase
C0L89_03860	COG2205	protein histidine kinase activity
C0L89_03865	COG0745	RESPONSE REGULATOR receiver
C0L89_03890	COG3791	Glutathione-dependent formaldehyde-activating
C0L89_03905	COG3039	Transposase
C0L89_03920	COG0488	(ABC) transporter
C0L89_03950	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C0L89_03960	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C0L89_03960	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C0L89_03990	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C0L89_04015	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
C0L89_04020	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
C0L89_04030	COG2205	protein histidine kinase activity
C0L89_04035	COG0745	RESPONSE REGULATOR receiver
C0L89_04065	COG0277	FAD linked oxidase domain protein
C0L89_04120	COG3116	cell division
C0L89_04135	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C0L89_04140	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C0L89_04160	COG1181	Belongs to the D-alanine--D-alanine ligase family
C0L89_04165	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C0L89_04190	COG0739	heme binding
C0L89_04190	COG1196	nuclear chromosome segregation
C0L89_04190	COG0741	lytic transglycosylase activity
C0L89_04205	COG0494	nUDIX hydrolase
C0L89_04220	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C0L89_04235	COG3321	synthase
C0L89_04235	COG1028	Short-chain dehydrogenase reductase Sdr
C0L89_04235	COG0604	alcohol dehydrogenase
C0L89_04295	COG2226	methyltransferase
C0L89_04340	COG2826	transposase and inactivated derivatives, IS30 family
C0L89_04365	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
C0L89_04380	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C0L89_04390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C0L89_04395	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C0L89_04405	COG0667	Aldo Keto reductase
C0L89_04435	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
C0L89_04445	COG2175	clavaminate synthase activity
C0L89_04455	COG4181	ATPase activity
C0L89_04470	COG0642	Histidine kinase
C0L89_04485	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C0L89_04525	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C0L89_04550	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
C0L89_04565	COG0123	including yeast histone deacetylase and acetoin utilization protein
C0L89_04570	COG2096	Adenosyltransferase
C0L89_04585	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C0L89_04590	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C0L89_04610	COG1802	Transcriptional regulator
C0L89_04620	COG3384	dioxygenase
C0L89_04625	COG0583	DNA-binding transcription factor activity
C0L89_04630	COG0318	PFAM AMP-dependent synthetase and ligase
C0L89_04640	COG1024	Enoyl-CoA hydratase
C0L89_04660	COG3386	PFAM SMP-30 Gluconolaconase
C0L89_04710	COG2197	response regulator
C0L89_04720	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C0L89_04725	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C0L89_04730	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C0L89_04740	COG0583	DNA-binding transcription factor activity
C0L89_04745	COG3634	alkyl hydroperoxide reductase activity
C0L89_04755	COG2890	protein-(glutamine-N5) methyltransferase activity
C0L89_04795	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C0L89_04795	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C0L89_04810	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
C0L89_04835	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
C0L89_04840	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
C0L89_04865	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C0L89_04875	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C0L89_04905	COG1295	ribonuclease BN
C0L89_04910	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C0L89_04915	COG1254	Belongs to the acylphosphatase family
C0L89_04930	COG0521	Mo-molybdopterin cofactor biosynthetic process
C0L89_04945	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
C0L89_04970	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C0L89_04985	COG0012	GTP binding
C0L89_05015	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C0L89_05020	COG0250	Participates in transcription elongation, termination and antitermination
C0L89_05035	COG0081	regulation of translation
C0L89_05040	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C0L89_05060	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
C0L89_05090	COG0051	transcription antitermination factor activity, RNA binding
C0L89_05105	COG0089	rRNA binding
C0L89_05110	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C0L89_05130	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
C0L89_05135	COG0255	Belongs to the universal ribosomal protein uL29 family
C0L89_05140	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
C0L89_05150	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
C0L89_05160	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C0L89_05180	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
C0L89_05185	COG1841	ribosomal large subunit assembly
C0L89_05190	COG0200	Binds to the 23S rRNA
C0L89_05195	COG0201	protein transport
C0L89_05200	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C0L89_05215	COG0202	RNA polymerase activity
C0L89_05220	COG0203	ribosomal protein L17
C0L89_05235	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
C0L89_05260	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C0L89_05270	COG0625	glutathione transferase activity
C0L89_05300	COG3039	Transposase
C0L89_05320	COG1902	pentaerythritol trinitrate reductase activity
C0L89_05320	COG0446	pyridine nucleotide-disulphide oxidoreductase
C0L89_05325	COG0604	alcohol dehydrogenase
C0L89_05355	COG0156	8-amino-7-oxononanoate synthase activity
C0L89_05360	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C0L89_05365	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
C0L89_05370	COG4208	sulfate ABC transporter
C0L89_05375	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
C0L89_05385	COG1063	alcohol dehydrogenase
C0L89_05410	COG0406	alpha-ribazole phosphatase activity
C0L89_05420	COG0285	dihydrofolate synthase activity
C0L89_05440	COG2833	Protein of unknown function (DUF455)
C0L89_05470	COG0671	phosphoesterase, PA-phosphatase related
C0L89_05475	COG0438	transferase activity, transferring glycosyl groups
C0L89_05485	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
C0L89_05490	COG5002	protein histidine kinase activity
C0L89_05500	COG4783	chaperone-mediated protein folding
C0L89_05515	COG0473	3-isopropylmalate dehydrogenase activity
C0L89_05560	COG3039	Transposase
C0L89_05585	COG0544	peptidyl-prolyl cis-trans isomerase activity
C0L89_05590	COG0740	serine-type endopeptidase activity
C0L89_05625	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C0L89_05650	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C0L89_05665	COG0631	protein serine/threonine phosphatase activity
C0L89_05685	COG3039	Transposase
C0L89_05695	COG0859	PFAM glycosyl transferase family 9
C0L89_05705	COG1234	tRNA 3'-trailer cleavage
C0L89_05710	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C0L89_05725	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C0L89_05730	COG0314	molybdopterin synthase activity
C0L89_05765	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
C0L89_05775	COG0537	adenosine 5'-monophosphoramidase activity
C0L89_05795	COG0714	Associated with various cellular activities
C0L89_05815	COG1399	metal-binding, possibly nucleic acid-binding protein
C0L89_05840	COG1028	Short-chain dehydrogenase reductase Sdr
C0L89_05855	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C0L89_05860	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C0L89_05890	COG3829	transcription factor binding
C0L89_05990	COG0330	HflC and HflK could
C0L89_05995	COG0330	HflC and HflK could
C0L89_06005	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C0L89_06010	COG0308	aminopeptidase N
C0L89_06035	COG0732	type I restriction modification DNA specificity domain
C0L89_06050	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
C0L89_06090	COG0328	RNA-DNA hybrid ribonuclease activity
C0L89_06090	COG0406	alpha-ribazole phosphatase activity
C0L89_06135	COG0587	DNA-directed DNA polymerase activity
C0L89_06155	COG1297	OPT oligopeptide transporter protein
C0L89_06170	COG1506	peptidase
C0L89_06170	COG0823	Involved in the tonB-independent uptake of proteins
C0L89_06180	COG2207	Transcriptional regulator
C0L89_06180	COG1917	Cupin 2, conserved barrel domain protein
C0L89_06225	COG0753	catalase activity
C0L89_06265	COG3551	Protein conserved in bacteria
C0L89_06295	COG2194	sulfuric ester hydrolase activity
C0L89_06305	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C0L89_06310	COG0745	RESPONSE REGULATOR receiver
C0L89_06315	COG0642	Histidine kinase
C0L89_06325	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
C0L89_06330	COG2894	cell division
C0L89_06345	COG4585	Histidine kinase
C0L89_06350	COG2197	response regulator
C0L89_06365	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C0L89_06390	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
C0L89_06450	COG3501	Rhs element vgr protein
C0L89_06460	COG2826	transposase and inactivated derivatives, IS30 family
C0L89_06485	COG3039	Transposase
C0L89_06565	COG3501	Rhs element vgr protein
C0L89_06620	COG1842	Phage shock protein A
C0L89_06645	COG0754	glutathionylspermidine amidase activity
C0L89_06725	COG0531	amino acid
C0L89_06730	COG2197	response regulator
C0L89_06745	COG1113	amino acid transport
C0L89_06775	COG3039	Transposase
C0L89_06785	COG1294	oxidase, subunit
C0L89_06795	COG2239	Acts as a magnesium transporter
C0L89_06805	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C0L89_06810	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C0L89_06825	COG3039	Transposase
C0L89_06850	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C0L89_06865	COG1137	ATPase activity
C0L89_06870	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
C0L89_06880	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
C0L89_06890	COG0271	Belongs to the BolA IbaG family
C0L89_06895	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C0L89_06920	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C0L89_06945	COG0628	permease
C0L89_06955	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C0L89_06960	COG3178	'Phosphotransferase
C0L89_06970	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C0L89_06975	COG1555	photosystem II stabilization
C0L89_07000	COG3039	Transposase
C0L89_07025	COG2826	transposase and inactivated derivatives, IS30 family
C0L89_07035	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C0L89_07040	COG0719	Fe-S assembly protein
C0L89_07045	COG0396	ATPase activity
C0L89_07050	COG0719	Fe-S assembly protein
C0L89_07055	COG1959	2 iron, 2 sulfur cluster binding
C0L89_07110	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C0L89_07145	COG0519	Catalyzes the synthesis of GMP from XMP
C0L89_07160	COG1678	Uncharacterized ACR, COG1678
C0L89_07170	COG0540	Belongs to the ATCase OTCase family
C0L89_07180	COG1764	response to oxidative stress
C0L89_07190	COG0384	phenazine biosynthesis protein PhzF
C0L89_07200	COG0527	aspartate kinase activity
C0L89_07230	COG3039	Transposase
C0L89_07240	COG0142	geranyltranstransferase activity
C0L89_07245	COG0629	single-stranded DNA binding
C0L89_07250	COG4251	negative regulation of phosphorylation
C0L89_07250	COG5001	Diguanylate cyclase
C0L89_07250	COG2203	Gaf domain
C0L89_07250	COG3706	GGDEF domain
C0L89_07295	COG2879	small protein
C0L89_07300	COG1966	Carbon starvation protein
C0L89_07305	COG1741	Belongs to the pirin family
C0L89_07315	COG3501	Rhs element vgr protein
C0L89_07410	COG1515	deoxyribonuclease V activity
C0L89_07430	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C0L89_07435	COG2202	Pas domain
C0L89_07435	COG2200	EAL domain
C0L89_07435	COG2199	diguanylate cyclase activity
C0L89_07440	COG0835	chemotaxis
C0L89_07445	COG0840	transmembrane signaling receptor activity
C0L89_07455	COG2198	Histidine kinase
C0L89_07455	COG0643	Histidine kinase
C0L89_07465	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C0L89_07475	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
C0L89_07515	COG0735	belongs to the Fur family
C0L89_07545	COG2826	transposase and inactivated derivatives, IS30 family
C0L89_07685	COG5002	protein histidine kinase activity
C0L89_07685	COG5001	Diguanylate cyclase
C0L89_07690	COG1187	pseudouridine synthase activity
C0L89_07715	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C0L89_07720	COG0475	glutathione-regulated potassium exporter activity
C0L89_07725	COG5002	protein histidine kinase activity
C0L89_07725	COG5000	phosphorelay sensor kinase activity
C0L89_07730	COG0745	RESPONSE REGULATOR receiver
C0L89_07735	COG1538	Outer membrane efflux protein
C0L89_07760	COG1132	(ABC) transporter
C0L89_07825	COG3118	belongs to the thioredoxin family
C0L89_07855	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C0L89_07875	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
C0L89_07900	COG2968	Membrane
C0L89_07910	COG1530	ribonuclease E activity
C0L89_07915	COG3164	Protein of unknown function
C0L89_07925	COG0312	modulator of DNA gyrase
C0L89_07930	COG3028	Belongs to the UPF0307 family
C0L89_07935	COG0312	modulator of DNA gyrase
C0L89_07950	COG4104	PAAR repeat-containing protein
C0L89_07960	COG0142	geranyltranstransferase activity
C0L89_07965	COG1722	exodeoxyribonuclease VII activity
C0L89_07970	COG0037	tRNA processing
C0L89_07975	COG1785	Belongs to the alkaline phosphatase family
C0L89_07980	COG1301	dicarboxylic acid transport
C0L89_07985	COG4106	trans-aconitate 2-methyltransferase activity
C0L89_07995	COG0791	NLP P60 protein
C0L89_08000	COG0791	NLP P60 protein
C0L89_08005	COG1047	Peptidyl-prolyl cis-trans
C0L89_08010	COG2311	Membrane
C0L89_08015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C0L89_08045	COG3039	Transposase
C0L89_08055	COG2826	transposase and inactivated derivatives, IS30 family
C0L89_08085	COG2826	transposase and inactivated derivatives, IS30 family
C0L89_08090	COG3039	Transposase
C0L89_08105	COG0489	protein tyrosine kinase activity
C0L89_08115	COG0717	Belongs to the dCTP deaminase family
C0L89_08130	COG3039	Transposase
C0L89_08150	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C0L89_08160	COG3039	Transposase
C0L89_08170	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C0L89_08190	COG0433	COG0433 Predicted ATPase
C0L89_08220	COG2890	protein-(glutamine-N5) methyltransferase activity
C0L89_08230	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C0L89_08235	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C0L89_08270	COG0133	tryptophan synthase activity
C0L89_08345	COG1028	Short-chain dehydrogenase reductase Sdr
C0L89_08365	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C0L89_08385	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
C0L89_08390	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
C0L89_08395	COG1034	ATP synthesis coupled electron transport
C0L89_08400	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
C0L89_08405	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C0L89_08415	COG0713	ATP synthesis coupled electron transport
C0L89_08430	COG1007	ATP synthesis coupled electron transport
C0L89_08445	COG0195	Participates in both transcription termination and antitermination
C0L89_08450	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
C0L89_08465	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
C0L89_08500	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C0L89_08505	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C0L89_08515	COG2095	MarC family integral membrane protein
C0L89_08530	COG1611	Belongs to the LOG family
C0L89_08575	COG4969	Belongs to the N-Me-Phe pilin family
C0L89_08580	COG0556	nucleotide-excision repair
C0L89_08610	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
C0L89_08620	COG2986	histidine ammonia-lyase
C0L89_08670	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C0L89_08675	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
C0L89_08680	COG0077	Prephenate dehydratase
C0L89_08680	COG1605	Chorismate mutase
C0L89_08710	COG3039	Transposase
C0L89_08720	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
C0L89_08735	COG0583	DNA-binding transcription factor activity
C0L89_08750	COG2336	PFAM SpoVT AbrB
C0L89_08795	COG0840	transmembrane signaling receptor activity
C0L89_08820	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
C0L89_08825	COG4191	Histidine kinase
C0L89_08825	COG0784	Response regulator, receiver
C0L89_08840	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C0L89_08860	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C0L89_08875	COG1595	DNA-templated transcription, initiation
C0L89_08925	COG2244	polysaccharide biosynthetic process
C0L89_08955	COG2264	protein methyltransferase activity
C0L89_08965	COG0438	transferase activity, transferring glycosyl groups
C0L89_08980	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
C0L89_08985	COG1132	(ABC) transporter
C0L89_08995	COG2271	Major facilitator Superfamily
C0L89_09015	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C0L89_09030	COG1253	flavin adenine dinucleotide binding
C0L89_09045	COG0306	phosphate transporter
C0L89_09085	COG0148	phosphopyruvate hydratase activity
C0L89_09115	COG2840	Smr protein MutS2
C0L89_09130	COG1238	metal cluster binding
C0L89_09145	COG1534	Rna-binding protein
C0L89_09155	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C0L89_09160	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C0L89_09170	COG1923	regulation of RNA biosynthetic process
C0L89_09175	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C0L89_09180	COG1546	Belongs to the CinA family
C0L89_09205	COG2137	regulation of response to DNA damage stimulus
C0L89_09215	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
C0L89_09270	COG1741	Belongs to the pirin family
C0L89_09275	COG0583	DNA-binding transcription factor activity
C0L89_09300	COG0351	phosphomethylpyrimidine kinase
C0L89_09300	COG0352	thiamine-phosphate diphosphorylase activity
C0L89_09310	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
C0L89_09315	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C0L89_09330	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C0L89_09340	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
C0L89_09345	COG3734	2-keto-3-deoxy-galactonokinase
C0L89_09360	COG0800	Aldolase
C0L89_09385	COG1070	Carbohydrate kinase
C0L89_09395	COG0477	Major facilitator Superfamily
C0L89_09415	COG0860	N-Acetylmuramoyl-L-alanine amidase
C0L89_09430	COG0617	tRNA 3'-terminal CCA addition
C0L89_09450	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
C0L89_09480	COG1472	Belongs to the glycosyl hydrolase 3 family
C0L89_09500	COG3706	GGDEF domain
C0L89_09500	COG2203	Gaf domain
C0L89_09500	COG5001	Diguanylate cyclase
C0L89_09500	COG4251	negative regulation of phosphorylation
C0L89_09510	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
C0L89_09520	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
C0L89_09535	COG0671	phosphoesterase, PA-phosphatase related
C0L89_09555	COG1794	racemase activity, acting on amino acids and derivatives
C0L89_09565	COG0697	spore germination
C0L89_09570	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C0L89_09595	COG1012	belongs to the aldehyde dehydrogenase family
C0L89_09655	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C0L89_09670	COG0124	histidyl-tRNA synthetase
C0L89_09730	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C0L89_09730	COG0140	phosphoribosyl-ATP diphosphatase activity
C0L89_09760	COG0235	Class ii aldolase
C0L89_09765	COG0531	amino acid
C0L89_09770	COG0531	amino acid
C0L89_09780	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C0L89_09785	COG0277	FAD linked oxidase domain protein
C0L89_09860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C0L89_09865	COG2258	MOSC domain
C0L89_09870	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
C0L89_09875	COG0505	Belongs to the CarA family
C0L89_09885	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C0L89_09890	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C0L89_09900	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C0L89_09915	COG3279	Response regulator of the LytR AlgR family
C0L89_09940	COG2205	protein histidine kinase activity
C0L89_09940	COG0784	Response regulator, receiver
C0L89_09940	COG2198	Histidine kinase
C0L89_09945	COG1024	Enoyl-CoA hydratase
C0L89_09950	COG0318	PFAM AMP-dependent synthetase and ligase
C0L89_09980	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C0L89_10010	COG0840	transmembrane signaling receptor activity
C0L89_10020	COG0835	chemotaxis
C0L89_10035	COG0840	transmembrane signaling receptor activity
C0L89_10040	COG0840	transmembrane signaling receptor activity
C0L89_10045	COG0840	transmembrane signaling receptor activity
C0L89_10060	COG0840	transmembrane signaling receptor activity
C0L89_10070	COG0840	transmembrane signaling receptor activity
C0L89_10075	COG0840	transmembrane signaling receptor activity
C0L89_10105	COG0840	transmembrane signaling receptor activity
C0L89_10110	COG2826	transposase and inactivated derivatives, IS30 family
C0L89_10130	COG0745	RESPONSE REGULATOR receiver
C0L89_10140	COG0835	chemotaxis
C0L89_10145	COG1192	Involved in chromosome partitioning
C0L89_10150	COG1360	Flagellar Motor Protein
C0L89_10155	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C0L89_10175	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C0L89_10215	COG3039	Transposase
C0L89_10280	COG2198	Histidine kinase
C0L89_10280	COG0643	Histidine kinase
C0L89_10300	COG0455	bacterial-type flagellum organization
C0L89_10325	COG3300	MHYT domain
C0L89_10325	COG5001	Diguanylate cyclase
C0L89_10330	COG3300	MHYT domain
C0L89_10330	COG5001	Diguanylate cyclase
C0L89_10335	COG1684	flagellar biosynthetic protein fliR
C0L89_10340	COG1987	bacterial-type flagellum assembly
C0L89_10350	COG3190	flagellar
C0L89_10400	COG1677	Flagellar hook-basal body complex protein FliE
C0L89_10435	COG1028	Short-chain dehydrogenase reductase Sdr
C0L89_10445	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C0L89_10460	COG2204	response regulator
C0L89_10465	COG2201	protein-glutamate methylesterase activity
C0L89_10495	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C0L89_10500	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C0L89_10515	COG1705	Flagellar rod assembly protein muramidase FlgJ
C0L89_10515	COG3951	Flagellar rod assembly protein muramidase FlgJ
C0L89_10520	COG1706	bacterial-type flagellum-dependent cell motility
C0L89_10525	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
C0L89_10530	COG4786	Flagellar basal body rod
C0L89_10540	COG4787	bacterial-type flagellum-dependent cell motility
C0L89_10545	COG1749	Flagellar hook protein flgE
C0L89_10550	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
C0L89_10555	COG1558	bacterial-type flagellum-dependent cell motility
C0L89_10565	COG0784	Response regulator, receiver
C0L89_10565	COG0835	chemotaxis
C0L89_10585	COG5002	protein histidine kinase activity
C0L89_10595	COG4585	Histidine kinase
C0L89_10630	COG0482	sulfurtransferase activity
C0L89_10640	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
C0L89_10645	COG0542	response to heat
C0L89_10650	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C0L89_10670	COG0492	ferredoxin-NADP+ reductase activity
C0L89_10675	COG1674	ftsk spoiiie
C0L89_10700	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C0L89_10720	COG0038	chloride channel
C0L89_10725	COG0183	Belongs to the thiolase family
C0L89_10730	COG1024	Enoyl-CoA hydratase
C0L89_10730	COG1250	3-hydroxyacyl-CoA dehydrogenase
C0L89_10740	COG0105	UTP biosynthetic process
C0L89_10765	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C0L89_10770	COG1160	GTP binding
C0L89_10775	COG0303	'Molybdopterin
C0L89_10785	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C0L89_10795	COG2826	transposase and inactivated derivatives, IS30 family
C0L89_10805	COG3039	Transposase
C0L89_10830	COG0746	molybdenum cofactor guanylyltransferase activity
C0L89_10855	COG1648	precorrin-2 dehydrogenase activity
C0L89_10855	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C0L89_10895	COG3039	Transposase
C0L89_10920	COG5001	Diguanylate cyclase
C0L89_10930	COG4566	intracellular signal transduction
C0L89_10980	COG3501	Rhs element vgr protein
C0L89_10985	COG2201	protein-glutamate methylesterase activity
C0L89_11065	COG1024	Enoyl-CoA hydratase
C0L89_11070	COG1024	Enoyl-CoA hydratase
C0L89_11080	COG1024	Enoyl-CoA hydratase
C0L89_11095	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
C0L89_11110	COG3039	Transposase
C0L89_11125	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C0L89_11130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C0L89_11180	COG1858	cytochrome C peroxidase
C0L89_11215	COG0631	protein serine/threonine phosphatase activity
C0L89_11250	COG3501	Rhs element vgr protein
C0L89_11280	COG3039	Transposase
C0L89_11365	COG3039	Transposase
C0L89_11380	COG2154	pterin-4-alpha-carbinolamine dehydratase
C0L89_11395	COG3064	Membrane
C0L89_11405	COG1530	ribonuclease E activity
C0L89_11440	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
C0L89_11490	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C0L89_11515	COG0811	peptide transport
C0L89_11540	COG4591	ABC-type transport system involved in lipoprotein release permease component
C0L89_11555	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C0L89_11570	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
C0L89_11585	COG0354	folic acid binding
C0L89_11600	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C0L89_11610	COG0363	glucosamine-6-phosphate deaminase activity
C0L89_11615	COG0129	dihydroxy-acid dehydratase activity
C0L89_11620	COG0800	Aldolase
C0L89_11700	COG0784	Response regulator, receiver
C0L89_11700	COG2205	protein histidine kinase activity
C0L89_11715	COG2183	response to ionizing radiation
C0L89_11725	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C0L89_11725	COG0723	plastoquinol--plastocyanin reductase activity
C0L89_11740	COG3243	poly(R)-hydroxyalkanoic acid synthase
C0L89_11750	COG1183	phosphatidylcholine synthase activity
C0L89_11755	COG1028	Short-chain dehydrogenase reductase Sdr
C0L89_11770	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
C0L89_11780	COG0668	transmembrane transport
C0L89_11790	COG0590	tRNA wobble adenosine to inosine editing
C0L89_11795	COG1321	iron dependent repressor
C0L89_11800	COG1914	H( )-stimulated, divalent metal cation uptake system
C0L89_11830	COG0583	DNA-binding transcription factor activity
C0L89_11855	COG0583	DNA-binding transcription factor activity
C0L89_11860	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C0L89_11870	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C0L89_11870	COG0519	Catalyzes the synthesis of GMP from XMP
C0L89_11895	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C0L89_11905	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C0L89_11910	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
C0L89_11925	COG0539	negative regulation of cytoplasmic translation
C0L89_11930	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
C0L89_11935	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C0L89_11945	COG2957	Belongs to the agmatine deiminase family
C0L89_11955	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C0L89_11980	COG0395	ABC-type sugar transport system, permease component
C0L89_11985	COG1175	transmembrane transport
C0L89_12015	COG2350	Protein conserved in bacteria
C0L89_12020	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
C0L89_12025	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C0L89_12030	COG1187	pseudouridine synthase activity
C0L89_12050	COG0436	Aminotransferase
C0L89_12055	COG4133	protoheme IX ABC transporter activity
C0L89_12105	COG1278	Cold shock
C0L89_12115	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C0L89_12120	COG4988	ABC transporter
C0L89_12130	COG1271	oxidase subunit
C0L89_12200	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C0L89_12205	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C0L89_12210	COG0137	argininosuccinate synthase activity
C0L89_12215	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C0L89_12230	COG2166	iron-sulfur cluster assembly
C0L89_12245	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C0L89_12255	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C0L89_12270	COG4302	ethanolamine ammonia-lyase activity
C0L89_12285	COG4677	pectinesterase activity
C0L89_12290	COG2826	transposase and inactivated derivatives, IS30 family
C0L89_12320	COG0402	S-adenosylhomocysteine deaminase activity
C0L89_12340	COG1509	lysine 2,3-aminomutase activity
C0L89_12345	COG5001	Diguanylate cyclase
C0L89_12345	COG3300	MHYT domain
C0L89_12360	COG0483	inositol monophosphate 1-phosphatase activity
C0L89_12395	COG0513	Belongs to the DEAD box helicase family
C0L89_12405	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
C0L89_12415	COG0625	glutathione transferase activity
C0L89_12430	COG4681	YaeQ
C0L89_12435	COG2081	HI0933 family
C0L89_12440	COG1716	ATPase activity
C0L89_12440	COG5001	Diguanylate cyclase
C0L89_12445	COG0501	Belongs to the peptidase M48B family
C0L89_12455	COG1028	Short-chain dehydrogenase reductase Sdr
C0L89_12480	COG0860	N-Acetylmuramoyl-L-alanine amidase
C0L89_12485	COG0802	atpase or kinase
C0L89_12490	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C0L89_12490	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
C0L89_12495	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C0L89_12515	COG3039	Transposase
C0L89_12525	COG1262	PFAM Formylglycine-generating sulfatase enzyme
C0L89_12575	COG0835	chemotaxis
C0L89_12580	COG0840	transmembrane signaling receptor activity
C0L89_12610	COG2969	positive regulation of protein catabolic process
C0L89_12615	COG0625	glutathione transferase activity
C0L89_12620	COG2857	Cytochrome c1
C0L89_12625	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C0L89_12630	COG0723	plastoquinol--plastocyanin reductase activity
C0L89_12640	COG0741	lytic transglycosylase activity
C0L89_12665	COG1702	phosphate starvation-inducible protein PhoH
C0L89_12685	COG4535	Mg2 and Co2 transporter CorC
C0L89_12700	COG1012	belongs to the aldehyde dehydrogenase family
C0L89_12705	COG1177	transmembrane transport
C0L89_12710	COG1176	ABC-type spermidine putrescine transport system, permease component I
C0L89_12720	COG3842	ATPase activity
C0L89_12750	COG3039	Transposase
C0L89_12775	COG0174	glutamine synthetase
C0L89_12780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C0L89_12785	COG3706	GGDEF domain
C0L89_12785	COG0745	RESPONSE REGULATOR receiver
C0L89_12790	COG0477	Major facilitator Superfamily
C0L89_12800	COG0243	molybdopterin cofactor binding
C0L89_12825	COG1121	(ABC) transporter
C0L89_12835	COG2733	membrane
C0L89_12840	COG0784	Response regulator, receiver
C0L89_12840	COG2205	protein histidine kinase activity
C0L89_12840	COG5002	protein histidine kinase activity
C0L89_12850	COG3039	Transposase
C0L89_12855	COG2902	Dehydrogenase
C0L89_12865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C0L89_12870	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C0L89_12885	COG1609	Transcriptional regulator
C0L89_12890	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C0L89_12890	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C0L89_12895	COG1105	Belongs to the carbohydrate kinase PfkB family
C0L89_12900	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C0L89_12900	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C0L89_12910	COG3501	Rhs element vgr protein
C0L89_12925	COG2826	transposase and inactivated derivatives, IS30 family
C0L89_12965	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C0L89_12975	COG1862	Preprotein translocase
C0L89_13045	COG0405	Gamma-glutamyltransferase
C0L89_13050	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C0L89_13070	COG0742	ribosomal rna small subunit methyltransferase
C0L89_13075	COG0326	Molecular chaperone. Has ATPase activity
C0L89_13120	COG4206	TonB-dependent receptor
C0L89_13170	COG0531	amino acid
C0L89_13185	COG0006	proline dipeptidase activity
C0L89_13195	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C0L89_13210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C0L89_13215	COG3938	Belongs to the proline racemase family
C0L89_13225	COG0552	protein localization to endoplasmic reticulum
C0L89_13240	COG1194	a g-specific adenine glycosylase
C0L89_13250	COG0784	Response regulator, receiver
C0L89_13250	COG4191	Histidine kinase
C0L89_13255	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C0L89_13280	COG3040	lipid binding
C0L89_13290	COG1960	acyl-CoA dehydrogenase activity
C0L89_13340	COG0438	transferase activity, transferring glycosyl groups
C0L89_13345	COG0438	transferase activity, transferring glycosyl groups
C0L89_13390	COG0776	regulation of translation
C0L89_13400	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C0L89_13405	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
C0L89_13410	COG0291	Belongs to the bacterial ribosomal protein bL35 family
C0L89_13415	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C0L89_13455	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
C0L89_13460	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C0L89_13465	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C0L89_13470	COG3115	cell septum assembly
C0L89_13495	COG0316	Belongs to the HesB IscA family
C0L89_13530	COG0288	reversible hydration of carbon dioxide
C0L89_13555	COG3844	kynureninase activity
C0L89_13565	COG2925	Exonuclease
C0L89_13575	COG0667	Aldo Keto reductase
C0L89_13590	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C0L89_13650	COG0494	nUDIX hydrolase
C0L89_13660	COG1024	Enoyl-CoA hydratase
C0L89_13670	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C0L89_13675	COG0659	secondary active sulfate transmembrane transporter activity
C0L89_13700	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C0L89_13705	COG0573	inorganic phosphate transmembrane transporter activity
C0L89_13710	COG0581	inorganic phosphate transmembrane transporter activity
C0L89_13720	COG0704	Plays a role in the regulation of phosphate uptake
C0L89_13730	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C0L89_13740	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C0L89_13755	COG0557	exoribonuclease II activity
C0L89_13785	COG1960	acyl-CoA dehydrogenase activity
C0L89_13795	COG0646	methionine synthase
C0L89_13795	COG1410	methionine synthase
C0L89_13800	COG0646	methionine synthase
C0L89_13800	COG1410	methionine synthase
C0L89_13810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C0L89_13850	COG0386	Belongs to the glutathione peroxidase family
C0L89_13860	COG1725	Transcriptional regulator
C0L89_13865	COG1131	(ABC) transporter
C0L89_13905	COG3039	Transposase
C0L89_13935	COG2850	peptidyl-arginine hydroxylation
C0L89_13970	COG1132	(ABC) transporter
C0L89_14000	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
C0L89_14015	COG0443	Heat shock 70 kDa protein
C0L89_14030	COG0497	DNA recombination
C0L89_14040	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C0L89_14050	COG2914	Belongs to the UPF0125 (RnfH) family
C0L89_14060	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
C0L89_14085	COG3039	Transposase
C0L89_14140	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C0L89_14150	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
C0L89_14155	COG0174	glutamine synthetase
C0L89_14200	COG3706	GGDEF domain
C0L89_14235	COG0415	Belongs to the DNA photolyase family
C0L89_14240	COG0305	Participates in initiation and elongation during chromosome replication
C0L89_14250	COG0367	asparagine synthase
C0L89_14280	COG0084	hydrolase, TatD family'
C0L89_14285	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C0L89_14325	COG0840	transmembrane signaling receptor activity
C0L89_14340	COG3039	Transposase
C0L89_14350	COG3039	Transposase
C0L89_14385	COG0386	Belongs to the glutathione peroxidase family
C0L89_14485	COG2814	Major facilitator Superfamily
C0L89_14490	COG1566	PFAM secretion protein HlyD family protein
C0L89_14505	COG2207	Transcriptional regulator
C0L89_14535	COG4774	siderophore transport
C0L89_14545	COG0367	asparagine synthase
C0L89_14560	COG1393	Belongs to the ArsC family
C0L89_14580	COG0024	Methionine aminopeptidase
C0L89_14645	COG0575	Belongs to the CDS family
C0L89_14650	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
C0L89_14655	COG0750	zinc metalloprotease
C0L89_14670	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C0L89_14700	COG0825	malonyl-CoA metabolic process
C0L89_14775	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C0L89_14790	COG2040	homocysteine
C0L89_14795	COG0833	amino acid
C0L89_14800	COG0346	lactoylglutathione lyase activity
C0L89_14820	COG2878	Part of a membrane complex involved in electron transport
C0L89_14840	COG1595	DNA-templated transcription, initiation
C0L89_14865	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C0L89_14880	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C0L89_14885	COG0251	oxidation-reduction process
C0L89_14895	COG0392	lysyltransferase activity
C0L89_14895	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
C0L89_14935	COG2814	Major facilitator Superfamily
C0L89_14940	COG1902	pentaerythritol trinitrate reductase activity
C0L89_14955	COG2824	Alkylphosphonate utilization operon protein PhnA
C0L89_14965	COG1047	Peptidyl-prolyl cis-trans
C0L89_15005	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C0L89_15020	COG1451	nucleotide metabolic process
C0L89_15040	COG0183	Belongs to the thiolase family
C0L89_15055	COG0745	RESPONSE REGULATOR receiver
C0L89_15055	COG3706	GGDEF domain
C0L89_15070	COG1793	dna ligase
C0L89_15070	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
C0L89_15080	COG1793	dna ligase
C0L89_15085	COG1201	RNA secondary structure unwinding
C0L89_15105	COG1278	Cold shock
C0L89_15110	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
C0L89_15125	COG3046	protein related to deoxyribodipyrimidine photolyase
C0L89_15130	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
C0L89_15185	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C0L89_15200	COG1250	3-hydroxyacyl-CoA dehydrogenase
C0L89_15200	COG1024	Enoyl-CoA hydratase
C0L89_15220	COG1024	Enoyl-CoA hydratase
C0L89_15225	COG1960	acyl-CoA dehydrogenase activity
C0L89_15300	COG2353	YceI-like domain
C0L89_15325	COG1760	l-serine dehydratase
C0L89_15335	COG0626	cystathionine gamma-synthase activity
C0L89_15340	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C0L89_15345	COG0739	heme binding
C0L89_15355	COG1272	protein, Hemolysin III
C0L89_15375	COG0517	IMP dehydrogenase activity
C0L89_15375	COG0516	GMP reductase activity
C0L89_15380	COG0463	Glycosyl transferase, family 2
C0L89_15390	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
C0L89_15400	COG4771	TonB-dependent receptor
C0L89_15405	COG1309	transcriptional regulator
C0L89_15415	COG1960	acyl-CoA dehydrogenase activity
C0L89_15460	COG0330	HflC and HflK could
C0L89_15470	COG1742	UPF0060 membrane protein
C0L89_15475	COG3956	TIGRFAM MazG family protein
C0L89_15485	COG0494	nUDIX hydrolase
C0L89_15495	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C0L89_15500	COG0837	glucose binding
C0L89_15515	COG3858	chitin binding
C0L89_15515	COG1388	LysM domain
C0L89_15535	COG1472	Belongs to the glycosyl hydrolase 3 family
C0L89_15570	COG3537	Alpha-1,2-mannosidase
C0L89_15615	COG3142	Participates in the control of copper homeostasis
C0L89_15620	COG1446	asparaginase
C0L89_15630	COG2304	oxidoreductase activity
C0L89_15660	COG0840	transmembrane signaling receptor activity
C0L89_15665	COG0835	chemotaxis
C0L89_15680	COG0189	ligase activity
C0L89_15690	COG1397	ADP-ribosylglycohydrolase
C0L89_15700	COG1199	ATP-dependent helicase activity
C0L89_15710	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C0L89_15725	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C0L89_15775	COG1643	Atp-dependent helicase
C0L89_15780	COG0783	Belongs to the Dps family
C0L89_15795	COG0514	ATP-dependent DNA helicase (RecQ)
C0L89_15810	COG3039	Transposase
C0L89_15825	COG1187	pseudouridine synthase activity
C0L89_15885	COG0602	queuosine metabolic process
C0L89_15895	COG2885	chlorophyll binding
C0L89_15900	COG0823	Involved in the tonB-independent uptake of proteins
C0L89_15910	COG0848	biopolymer transport protein
C0L89_15920	COG0824	Thioesterase
C0L89_15940	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
C0L89_15960	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
C0L89_15975	COG0477	Major facilitator Superfamily
C0L89_16010	COG0488	(ABC) transporter
C0L89_16040	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C0L89_16040	COG4651	solute:proton antiporter activity
C0L89_16070	COG0640	Transcriptional regulator
C0L89_16085	COG4772	TonB-dependent receptor
C0L89_16095	COG4264	IucA IucC family
C0L89_16110	COG0019	diaminopimelate decarboxylase activity
C0L89_16165	COG4206	TonB-dependent receptor
C0L89_16195	COG0542	response to heat
C0L89_16220	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
C0L89_16230	COG0534	Mate efflux family protein
C0L89_16280	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C0L89_16285	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C0L89_16325	COG2172	sigma factor antagonist activity
C0L89_16330	COG1366	Belongs to the anti-sigma-factor antagonist family
C0L89_16335	COG1366	Belongs to the anti-sigma-factor antagonist family
C0L89_16345	COG0326	Molecular chaperone. Has ATPase activity
C0L89_16350	COG2207	Transcriptional regulator
C0L89_16390	COG3209	COG3209 Rhs family protein
C0L89_16400	COG3501	Rhs element vgr protein
C0L89_16410	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C0L89_16415	COG1845	cytochrome c oxidase, subunit III
C0L89_16420	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C0L89_16440	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
C0L89_16455	COG0728	peptidoglycan biosynthetic process
C0L89_16460	COG0268	Binds directly to 16S ribosomal RNA
C0L89_16480	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C0L89_16485	COG0824	Thioesterase
C0L89_16500	COG1946	Acyl-CoA thioesterase
C0L89_16510	COG1595	DNA-templated transcription, initiation
C0L89_16565	COG1877	trehalose-phosphatase activity
C0L89_16570	COG3387	PFAM Glycoside hydrolase 15-related
C0L89_16610	COG0564	pseudouridine synthase activity
C0L89_16615	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C0L89_16620	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C0L89_16620	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C0L89_16635	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C0L89_16680	COG2194	sulfuric ester hydrolase activity
C0L89_16685	COG4969	Belongs to the N-Me-Phe pilin family
C0L89_16695	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
C0L89_16700	COG0237	dephospho-CoA kinase activity
C0L89_16705	COG2205	protein histidine kinase activity
C0L89_16710	COG0745	RESPONSE REGULATOR receiver
C0L89_16730	COG3039	Transposase
C0L89_16745	COG3039	Transposase
C0L89_16775	COG3039	Transposase
C0L89_16815	COG3273	potassium ion transport
C0L89_16815	COG0471	metal ion transport
C0L89_16845	COG1970	mechanosensitive ion channel activity
C0L89_16880	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C0L89_16895	COG0308	aminopeptidase N
C0L89_16900	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C0L89_16910	COG0529	Catalyzes the synthesis of activated sulfate
C0L89_16910	COG2895	sulfate adenylyltransferase (ATP) activity
C0L89_16920	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C0L89_16950	COG2205	protein histidine kinase activity
C0L89_16950	COG0784	Response regulator, receiver
C0L89_16950	COG2198	Histidine kinase
C0L89_16995	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C0L89_17000	COG3588	fructose-bisphosphate aldolase
C0L89_17010	COG0469	pyruvate kinase activity
C0L89_17040	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C0L89_17055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C0L89_17055	COG3453	Protein conserved in bacteria
C0L89_17060	COG0725	ABC transporter, periplasmic molybdate-binding protein
C0L89_17065	COG4149	molybdate abc transporter
C0L89_17070	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
C0L89_17090	COG0642	Histidine kinase
C0L89_17095	COG0745	RESPONSE REGULATOR receiver
C0L89_17105	COG1028	Short-chain dehydrogenase reductase Sdr
C0L89_17115	COG1022	Amp-dependent synthetase and ligase
C0L89_17145	COG1376	ErfK ybiS ycfS ynhG family protein
C0L89_17150	COG0739	heme binding
C0L89_17165	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C0L89_17170	COG1301	dicarboxylic acid transport
C0L89_17190	COG2304	oxidoreductase activity
C0L89_17210	COG0714	Associated with various cellular activities
C0L89_17245	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
C0L89_17270	COG0254	rRNA binding
C0L89_17280	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C0L89_17290	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C0L89_17295	COG1758	RNA polymerase activity
C0L89_17310	COG1561	YicC-like family, N-terminal region
C0L89_17330	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C0L89_17360	COG0006	proline dipeptidase activity
C0L89_17385	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C0L89_17405	COG2912	Transglutaminase-like superfamily
C0L89_17410	COG1773	rubredoxin
C0L89_17415	COG0352	thiamine-phosphate diphosphorylase activity
C0L89_17445	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
C0L89_17485	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C0L89_17510	COG0671	phosphoesterase, PA-phosphatase related
C0L89_17525	COG3781	membrane
C0L89_17535	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C0L89_17550	COG3039	Transposase
C0L89_17565	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
C0L89_17575	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
C0L89_17600	COG3710	Transcriptional regulator
C0L89_17645	COG2226	methyltransferase
C0L89_17675	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
C0L89_17680	COG1538	Outer membrane efflux protein
C0L89_17685	COG1519	Transferase
C0L89_17690	COG1560	Kdo2-lipid A biosynthetic process
C0L89_17720	COG2826	transposase and inactivated derivatives, IS30 family
C0L89_17760	COG0281	malic enzyme
C0L89_17760	COG0280	phosphate acetyltransferase
C0L89_17780	COG4191	Histidine kinase
C0L89_17795	COG0583	DNA-binding transcription factor activity
C0L89_17815	COG2197	response regulator
C0L89_17825	COG0642	Histidine kinase
C0L89_17845	COG2851	Citrate transporter
C0L89_17850	COG1028	Short-chain dehydrogenase reductase Sdr
C0L89_17860	COG1609	Transcriptional regulator
C0L89_17865	COG2211	Major facilitator Superfamily
C0L89_17895	COG0436	Aminotransferase
C0L89_17920	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C0L89_17940	COG0402	S-adenosylhomocysteine deaminase activity
C0L89_17990	COG0242	peptide deformylase activity
C0L89_17995	COG3039	Transposase
C0L89_18025	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C0L89_18085	COG2188	Transcriptional regulator
C0L89_18100	COG1450	Type ii and iii secretion system protein
C0L89_18115	COG3166	PFAM Fimbrial assembly family protein
C0L89_18120	COG3156	type II secretion system protein K
C0L89_18125	COG4795	General secretion pathway protein
C0L89_18130	COG2165	general secretion pathway protein
C0L89_18135	COG4970	Tfp pilus assembly protein FimT
C0L89_18140	COG2165	general secretion pathway protein
C0L89_18145	COG1459	type II secretion system
C0L89_18155	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C0L89_18160	COG1404	Belongs to the peptidase S8 family
C0L89_18165	COG5295	Hep Hag repeat protein
C0L89_18175	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C0L89_18175	COG0047	phosphoribosylformylglycinamidine synthase activity
C0L89_18185	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C0L89_18190	COG4974	Belongs to the 'phage' integrase family
C0L89_18205	COG0795	lipopolysaccharide-transporting ATPase activity
C0L89_18240	COG0525	valine-tRNA ligase activity
C0L89_18280	COG2826	transposase and inactivated derivatives, IS30 family
C0L89_18290	COG2826	transposase and inactivated derivatives, IS30 family
C0L89_18315	COG1183	phosphatidylcholine synthase activity
C0L89_18340	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C0L89_18345	COG1127	ABC transporter
C0L89_18350	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C0L89_18350	COG3218	ABC-type transport auxiliary lipoprotein component
C0L89_18395	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C0L89_18400	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
C0L89_18400	COG0662	Cupin 2, conserved barrel domain protein
C0L89_18430	COG2086	electron transfer activity
C0L89_18490	COG0626	cystathionine gamma-synthase activity
C0L89_18520	COG0625	glutathione transferase activity
C0L89_18535	COG0513	Belongs to the DEAD box helicase family
C0L89_18545	COG0720	synthase
C0L89_18560	COG1956	GAF domain-containing protein
C0L89_18570	COG3039	Transposase
C0L89_18575	COG0546	phosphoglycolate phosphatase activity
C0L89_18605	COG0339	signal peptide processing
C0L89_18655	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C0L89_18740	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
C0L89_18750	COG0356	it plays a direct role in the translocation of protons across the membrane
C0L89_18770	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C0L89_18780	COG0508	dehydrogenase complex catalyzes the overall conversion of
C0L89_18815	COG2011	ABC-type metal ion transport system permease component
C0L89_18825	COG0697	spore germination
C0L89_18865	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C0L89_18870	COG1187	pseudouridine synthase activity
C0L89_18875	COG2813	Specifically methylates the guanine in position
C0L89_18905	COG2202	Pas domain
C0L89_18905	COG2205	protein histidine kinase activity
C0L89_18930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C0L89_18935	COG1522	sequence-specific DNA binding
C0L89_18980	COG0745	RESPONSE REGULATOR receiver
C0L89_18995	COG1404	Belongs to the peptidase S8 family
C0L89_19010	COG0842	Transport permease protein
C0L89_19015	COG1131	(ABC) transporter
C0L89_19020	COG0025	NhaP-type Na H and K H
C0L89_19030	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
C0L89_19040	COG1573	uracil-dna glycosylase
C0L89_19050	COG3384	dioxygenase
C0L89_19065	COG0667	Aldo Keto reductase
C0L89_19080	COG3590	peptidase
C0L89_19100	COG0531	amino acid
C0L89_19125	COG3685	Protein conserved in bacteria
C0L89_19130	COG3546	catalase activity
C0L89_19155	COG3039	Transposase
C0L89_19185	COG1271	oxidase subunit
C0L89_19190	COG1294	oxidase, subunit
C0L89_19225	COG1063	alcohol dehydrogenase
C0L89_19330	COG1473	amidohydrolase
C0L89_19335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C0L89_19340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C0L89_19365	COG5383	Protein conserved in bacteria
C0L89_19415	COG3023	N-Acetylmuramoyl-L-alanine amidase
C0L89_19425	COG4948	Mandelate Racemase Muconate Lactonizing
C0L89_19450	COG0531	amino acid
C0L89_19470	COG4682	membrane
C0L89_19475	COG2133	pyrroloquinoline quinone binding
C0L89_19495	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C0L89_19505	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C0L89_19515	COG1610	YqeY-like protein
C0L89_19535	COG1295	ribonuclease BN
C0L89_19540	COG0358	DNA primase activity
C0L89_19610	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
C0L89_19625	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C0L89_19690	COG0739	heme binding
C0L89_19705	COG2211	Major facilitator Superfamily
C0L89_19710	COG0708	Exodeoxyribonuclease III
C0L89_19745	COG3501	Rhs element vgr protein
C0L89_19840	COG0740	serine-type endopeptidase activity
C0L89_19845	COG4695	Portal protein
C0L89_19850	COG1802	Transcriptional regulator
C0L89_19850	COG4626	Terminase
C0L89_19955	COG0582	viral genome integration into host DNA
C0L89_19970	COG1192	Involved in chromosome partitioning
C0L89_19975	COG1475	DNA binding
C0L89_19990	COG0463	Glycosyl transferase, family 2
C0L89_20015	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C0L89_20040	COG4221	oxidoreductase activity
C0L89_20080	COG1166	arginine decarboxylase activity
C0L89_20130	COG0606	chelatase, subunit chli
C0L89_20155	COG4943	cyclic-guanylate-specific phosphodiesterase activity
C0L89_20175	COG3039	Transposase
C0L89_20235	COG1090	epimerase
C0L89_20245	COG0642	Histidine kinase
C0L89_20260	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C0L89_20295	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C0L89_20305	COG1595	DNA-templated transcription, initiation
C0L89_20310	COG0753	catalase activity
C0L89_20335	COG0697	spore germination
C0L89_20360	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C0L89_20365	COG0180	Tryptophanyl-tRNA synthetase
C0L89_20370	COG3237	CsbD-like
C0L89_20425	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
C0L89_20425	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
C0L89_20435	COG3228	Belongs to the MtfA family
C0L89_20450	COG2205	protein histidine kinase activity
C0L89_20455	COG0745	RESPONSE REGULATOR receiver
C0L89_20465	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C0L89_20520	COG3039	Transposase
C0L89_20525	COG1566	PFAM secretion protein HlyD family protein
C0L89_20540	COG1199	ATP-dependent helicase activity
C0L89_20585	COG0583	DNA-binding transcription factor activity
C0L89_20645	COG2826	transposase and inactivated derivatives, IS30 family
C0L89_20675	COG4555	ABC transporter
C0L89_20685	COG1476	TRANSCRIPTIONal
C0L89_20705	COG1230	cation diffusion facilitator family transporter
C0L89_20710	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C0L89_20715	COG1131	(ABC) transporter
C0L89_20720	COG0842	Transport permease protein
C0L89_20730	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C0L89_20785	COG2951	lytic endotransglycosylase activity
C0L89_20805	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C0L89_20815	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C0L89_20830	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C0L89_20830	COG0045	succinate-CoA ligase (ADP-forming) activity
C0L89_20830	COG1042	CoA-binding domain protein
C0L89_20840	COG2239	Acts as a magnesium transporter
C0L89_20865	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C0L89_20870	COG3387	PFAM Glycoside hydrolase 15-related
C0L89_20885	COG3100	YcgL domain-containing protein
C0L89_20890	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C0L89_20900	COG0463	Glycosyl transferase, family 2
C0L89_20915	COG1028	Short-chain dehydrogenase reductase Sdr
C0L89_20945	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C0L89_20960	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C0L89_21075	COG0210	DNA helicase
C0L89_21095	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C0L89_21110	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C0L89_21125	COG2159	amidohydrolase
C0L89_21130	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C0L89_21135	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C0L89_21155	COG0357	Ribosomal RNA small subunit methyltransferase G
C0L89_21160	COG3540	Alkaline phosphatase
C0L89_21170	COG2091	lysine biosynthetic process via aminoadipic acid
C0L89_21185	COG0708	Exodeoxyribonuclease III
C0L89_21200	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C0L89_21205	COG3162	membrane
C0L89_21260	COG1028	Short-chain dehydrogenase reductase Sdr
C0L89_21265	COG0179	Fumarylacetoacetate (FAA) hydrolase
C0L89_21275	COG4948	Mandelate Racemase Muconate Lactonizing
C0L89_21285	COG3039	Transposase
C0L89_21290	COG3254	rhamnose metabolic process
C0L89_21295	COG0738	Major facilitator superfamily
C0L89_21300	COG1414	Transcriptional regulator
C0L89_21310	COG2205	protein histidine kinase activity
C0L89_21320	COG3459	Glycosyltransferase 36 associated
C0L89_21325	COG2211	Major facilitator Superfamily
C0L89_21330	COG3265	gluconokinase activity
C0L89_21335	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C0L89_21375	COG3039	Transposase
C0L89_21385	COG3039	Transposase
C0L89_21390	COG2911	Protein conserved in bacteria
C0L89_21395	COG0729	surface antigen
C0L89_21400	COG4771	TonB-dependent receptor
C0L89_21405	COG0457	Tetratricopeptide repeat
C0L89_21415	COG0752	glycyl-tRNA synthetase alpha subunit
C0L89_21420	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C0L89_21430	COG0519	Catalyzes the synthesis of GMP from XMP
C0L89_21430	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C0L89_21440	COG0805	protein transport
C0L89_21445	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C0L89_21450	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C0L89_21460	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
C0L89_21490	COG2974	May be involved in recombination
C0L89_21495	COG0037	tRNA processing
C0L89_21520	COG3661	Belongs to the glycosyl hydrolase 67 family
C0L89_21530	COG4948	Mandelate Racemase Muconate Lactonizing
C0L89_21550	COG0246	Mannitol dehydrogenase
C0L89_21585	COG2826	transposase and inactivated derivatives, IS30 family
C0L89_21615	COG3693	PFAM glycoside hydrolase, family 10
C0L89_21640	COG2211	Major facilitator Superfamily
C0L89_21655	COG3039	Transposase
C0L89_21690	COG2937	Belongs to the GPAT DAPAT family
C0L89_21740	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
C0L89_21760	COG0210	DNA helicase
C0L89_21775	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
C0L89_21840	COG0676	glucose-6-phosphate 1-epimerase activity
C0L89_21855	COG0730	response to heat
C0L89_21890	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C0L89_21895	COG0302	gtp cyclohydrolase
C0L89_21925	COG2826	transposase and inactivated derivatives, IS30 family
C0L89_21935	COG0477	Major facilitator Superfamily
C0L89_21950	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C0L89_21995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C0L89_22055	COG3237	CsbD-like
C0L89_22090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C0L89_22145	COG4772	TonB-dependent receptor
C0L89_22155	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
C0L89_22190	COG3039	Transposase
C0L89_22245	COG0564	pseudouridine synthase activity
C0L89_22260	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C0L89_22295	COG3039	Transposase
C0L89_22315	COG2826	transposase and inactivated derivatives, IS30 family
C0L89_22380	COG1074	ATP-dependent DNA helicase activity
C0L89_22385	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
C0L89_22400	COG3039	Transposase
C0L89_22405	COG3039	Transposase
C0L89_22415	COG1136	(ABC) transporter
C0L89_22435	COG1127	ABC transporter
C0L89_22440	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C0L89_22445	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C0L89_22460	COG2853	Lipoprotein
C0L89_22475	COG0386	Belongs to the glutathione peroxidase family
C0L89_22485	COG1322	Protein conserved in bacteria
C0L89_22490	COG3039	Transposase
C0L89_22515	COG1929	Belongs to the glycerate kinase type-1 family
C0L89_22520	COG2271	Major facilitator Superfamily
C0L89_22535	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C0L89_22545	COG0861	Integral membrane protein TerC family
C0L89_22560	COG0584	glycerophosphoryl diester phosphodiesterase
C0L89_22570	COG0671	phosphoesterase, PA-phosphatase related
C0L89_22575	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
C0L89_22580	COG0726	polysaccharide deacetylase
C0L89_22595	COG0230	Belongs to the bacterial ribosomal protein bL34 family