locus-tag	class	description
PXO_00004	COG3501	Rhs element vgr protein
PXO_00006	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
PXO_00007	COG1845	cytochrome c oxidase, subunit III
PXO_00008	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PXO_00012	COG0196	riboflavin kinase activity
PXO_00013	COG0728	peptidoglycan biosynthetic process
PXO_00014	COG0268	Binds directly to 16S ribosomal RNA
PXO_00020	COG4771	TonB-dependent receptor
PXO_00022	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
PXO_00026	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
PXO_00027	COG1360	Flagellar Motor Protein
PXO_00028	COG1192	Involved in chromosome partitioning
PXO_00029	COG0835	chemotaxis
PXO_00031	COG0745	RESPONSE REGULATOR receiver
PXO_00036	COG0840	transmembrane signaling receptor activity
PXO_00039	COG0840	transmembrane signaling receptor activity
PXO_00041	COG0840	transmembrane signaling receptor activity
PXO_00043	COG0840	transmembrane signaling receptor activity
PXO_00045	COG0840	transmembrane signaling receptor activity
PXO_00046	COG0840	transmembrane signaling receptor activity
PXO_00047	COG0840	transmembrane signaling receptor activity
PXO_00050	COG0835	chemotaxis
PXO_00054	COG0840	transmembrane signaling receptor activity
PXO_00059	COG2267	carboxylic ester hydrolase activity
PXO_00067	COG0318	PFAM AMP-dependent synthetase and ligase
PXO_00068	COG1024	Enoyl-CoA hydratase
PXO_00069	COG2198	Histidine kinase
PXO_00069	COG2205	protein histidine kinase activity
PXO_00069	COG0784	Response regulator, receiver
PXO_00071	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
PXO_00072	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PXO_00083	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
PXO_00085	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PXO_00086	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
PXO_00088	COG0505	Belongs to the CarA family
PXO_00090	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
PXO_00092	COG2258	MOSC domain
PXO_00093	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PXO_00112	COG1070	Carbohydrate kinase
PXO_00115	COG1501	Belongs to the glycosyl hydrolase 31 family
PXO_00120	COG0800	Aldolase
PXO_00123	COG3734	2-keto-3-deoxy-galactonokinase
PXO_00124	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
PXO_00126	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PXO_00129	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PXO_00130	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
PXO_00132	COG0351	phosphomethylpyrimidine kinase
PXO_00136	COG0583	DNA-binding transcription factor activity
PXO_00137	COG1741	Belongs to the pirin family
PXO_00142	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PXO_00143	COG0305	Participates in initiation and elongation during chromosome replication
PXO_00146	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PXO_00148	COG2137	regulation of response to DNA damage stimulus
PXO_00153	COG1546	Belongs to the CinA family
PXO_00154	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PXO_00155	COG1923	regulation of RNA biosynthetic process
PXO_00156	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PXO_00157	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PXO_00158	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PXO_00160	COG1534	Rna-binding protein
PXO_00163	COG1238	metal cluster binding
PXO_00166	COG2840	Smr protein MutS2
PXO_00169	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
PXO_00181	COG0306	phosphate transporter
PXO_00183	COG1253	flavin adenine dinucleotide binding
PXO_00186	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PXO_00188	COG0477	Major facilitator Superfamily
PXO_00189	COG1132	(ABC) transporter
PXO_00190	COG1136	(ABC) transporter
PXO_00194	COG0438	transferase activity, transferring glycosyl groups
PXO_00196	COG2264	protein methyltransferase activity
PXO_00202	COG2244	polysaccharide biosynthetic process
PXO_00212	COG1595	DNA-templated transcription, initiation
PXO_00215	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PXO_00219	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PXO_00227	COG2201	protein-glutamate methylesterase activity
PXO_00230	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PXO_00231	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PXO_00237	COG2963	transposase activity
PXO_00238	COG3328	transposase activity
PXO_00240	COG4644	lycopene metabolic process
PXO_00242	COG1858	cytochrome C peroxidase
PXO_00247	COG0515	serine threonine protein kinase
PXO_00248	COG0631	protein serine/threonine phosphatase activity
PXO_00256	COG3501	Rhs element vgr protein
PXO_00258	COG3039	Transposase
PXO_00267	COG3039	Transposase
PXO_00270	COG3501	Rhs element vgr protein
PXO_00278	COG3039	Transposase
PXO_00284	COG3039	Transposase
PXO_00285	COG3209	COG3209 Rhs family protein
PXO_00285	COG3209	COG3209 Rhs family protein
PXO_00290	COG3328	transposase activity
PXO_00307	COG0405	Gamma-glutamyltransferase
PXO_00309	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PXO_00312	COG0742	ribosomal rna small subunit methyltransferase
PXO_00333	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
PXO_00334	COG4988	ABC transporter
PXO_00336	COG1271	oxidase subunit
PXO_00337	COG1294	oxidase, subunit
PXO_00349	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
PXO_00350	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PXO_00352	COG0137	argininosuccinate synthase activity
PXO_00353	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PXO_00356	COG2166	iron-sulfur cluster assembly
PXO_00359	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PXO_00361	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
PXO_00363	COG4302	ethanolamine ammonia-lyase activity
PXO_00368	COG3039	Transposase
PXO_00373	COG4677	pectinesterase activity
PXO_00380	COG0402	S-adenosylhomocysteine deaminase activity
PXO_00383	COG1509	lysine 2,3-aminomutase activity
PXO_00384	COG3300	MHYT domain
PXO_00384	COG5001	Diguanylate cyclase
PXO_00388	COG0483	inositol monophosphate 1-phosphatase activity
PXO_00394	COG0513	Belongs to the DEAD box helicase family
PXO_00395	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PXO_00396	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
PXO_00398	COG0625	glutathione transferase activity
PXO_00401	COG4681	YaeQ
PXO_00402	COG2081	HI0933 family
PXO_00404	COG0501	Belongs to the peptidase M48B family
PXO_00406	COG1028	Short-chain dehydrogenase reductase Sdr
PXO_00411	COG0860	N-Acetylmuramoyl-L-alanine amidase
PXO_00412	COG0802	atpase or kinase
PXO_00413	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
PXO_00413	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PXO_00414	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PXO_00415	COG1570	exodeoxyribonuclease VII activity
PXO_00418	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PXO_00428	COG3328	transposase activity
PXO_00437	COG2969	positive regulation of protein catabolic process
PXO_00438	COG0625	glutathione transferase activity
PXO_00439	COG2857	Cytochrome c1
PXO_00440	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
PXO_00441	COG0723	plastoquinol--plastocyanin reductase activity
PXO_00442	COG0741	lytic transglycosylase activity
PXO_00446	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PXO_00447	COG1702	phosphate starvation-inducible protein PhoH
PXO_00451	COG4535	Mg2 and Co2 transporter CorC
PXO_00454	COG1012	belongs to the aldehyde dehydrogenase family
PXO_00456	COG1177	transmembrane transport
PXO_00457	COG1176	ABC-type spermidine putrescine transport system, permease component I
PXO_00458	COG3842	ATPase activity
PXO_00464	COG0174	glutamine synthetase
PXO_00465	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PXO_00466	COG3706	GGDEF domain
PXO_00466	COG0745	RESPONSE REGULATOR receiver
PXO_00467	COG0477	Major facilitator Superfamily
PXO_00468	COG0243	molybdopterin cofactor binding
PXO_00472	COG1121	(ABC) transporter
PXO_00474	COG2733	membrane
PXO_00475	COG2205	protein histidine kinase activity
PXO_00475	COG0784	Response regulator, receiver
PXO_00475	COG5002	protein histidine kinase activity
PXO_00477	COG3039	Transposase
PXO_00479	COG2902	Dehydrogenase
PXO_00481	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PXO_00482	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PXO_00486	COG1609	Transcriptional regulator
PXO_00487	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PXO_00487	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
PXO_00488	COG1105	Belongs to the carbohydrate kinase PfkB family
PXO_00489	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PXO_00489	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PXO_00491	COG3039	Transposase
PXO_00502	COG3501	Rhs element vgr protein
PXO_00503	COG2963	transposase activity
PXO_00509	COG2963	transposase activity
PXO_00515	COG3328	transposase activity
PXO_00519	COG3039	Transposase
PXO_00521	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PXO_00524	COG1862	Preprotein translocase
PXO_00536	COG0704	Plays a role in the regulation of phosphate uptake
PXO_00538	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PXO_00542	COG0573	inorganic phosphate transmembrane transporter activity
PXO_00572	COG2201	protein-glutamate methylesterase activity
PXO_00574	COG2801	Transposase and inactivated derivatives
PXO_00578	COG3328	transposase activity
PXO_00584	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PXO_00590	COG0811	peptide transport
PXO_00597	COG4591	ABC-type transport system involved in lipoprotein release permease component
PXO_00600	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
PXO_00603	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
PXO_00606	COG0354	folic acid binding
PXO_00608	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PXO_00610	COG0363	glucosamine-6-phosphate deaminase activity
PXO_00611	COG0129	dihydroxy-acid dehydratase activity
PXO_00612	COG0800	Aldolase
PXO_00620	COG0784	Response regulator, receiver
PXO_00620	COG2205	protein histidine kinase activity
PXO_00620	COG5002	protein histidine kinase activity
PXO_00625	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PXO_00626	COG0431	NADPH-dependent FMN reductase
PXO_00627	COG1393	Belongs to the ArsC family
PXO_00628	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PXO_00630	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PXO_00636	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PXO_00641	COG1247	-acetyltransferase
PXO_00649	COG3706	GGDEF domain
PXO_00658	COG0386	Belongs to the glutathione peroxidase family
PXO_00660	COG0339	signal peptide processing
PXO_00678	COG3706	GGDEF domain
PXO_00678	COG4251	negative regulation of phosphorylation
PXO_00678	COG5001	Diguanylate cyclase
PXO_00678	COG2203	Gaf domain
PXO_00680	COG1472	Belongs to the glycosyl hydrolase 3 family
PXO_00687	COG0166	Belongs to the GPI family
PXO_00689	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
PXO_00690	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
PXO_00696	COG0860	N-Acetylmuramoyl-L-alanine amidase
PXO_00699	COG2963	transposase activity
PXO_00709	COG4566	intracellular signal transduction
PXO_00713	COG2963	transposase activity
PXO_00716	COG1605	Chorismate mutase
PXO_00716	COG0077	Prephenate dehydratase
PXO_00717	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PXO_00718	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PXO_00727	COG2986	histidine ammonia-lyase
PXO_00729	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
PXO_00733	COG2963	transposase activity
PXO_00737	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
PXO_00742	COG3115	cell septum assembly
PXO_00747	COG0316	Belongs to the HesB IscA family
PXO_00754	COG0288	reversible hydration of carbon dioxide
PXO_00758	COG3844	kynureninase activity
PXO_00762	COG2925	Exonuclease
PXO_00764	COG0667	Aldo Keto reductase
PXO_00778	COG0494	nUDIX hydrolase
PXO_00780	COG1024	Enoyl-CoA hydratase
PXO_00782	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PXO_00795	COG2183	response to ionizing radiation
PXO_00797	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
PXO_00801	COG0671	phosphoesterase, PA-phosphatase related
PXO_00804	COG1794	racemase activity, acting on amino acids and derivatives
PXO_00805	COG0697	spore germination
PXO_00806	COG0812	UDP-N-acetylmuramate dehydrogenase activity
PXO_00808	COG0167	dihydroorotate dehydrogenase activity
PXO_00811	COG1012	belongs to the aldehyde dehydrogenase family
PXO_00822	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
PXO_00827	COG0124	histidyl-tRNA synthetase
PXO_00846	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
PXO_00848	COG0235	Class ii aldolase
PXO_00849	COG0531	amino acid
PXO_00850	COG0531	amino acid
PXO_00852	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PXO_00853	COG0277	FAD linked oxidase domain protein
PXO_00866	COG0436	Aminotransferase
PXO_00871	COG1187	pseudouridine synthase activity
PXO_00872	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PXO_00873	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PXO_00874	COG2350	Protein conserved in bacteria
PXO_00876	COG1609	Transcriptional regulator
PXO_00877	COG1609	Transcriptional regulator
PXO_00881	COG1175	transmembrane transport
PXO_00882	COG0395	ABC-type sugar transport system, permease component
PXO_00886	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PXO_00887	COG2957	Belongs to the agmatine deiminase family
PXO_00889	COG0257	Belongs to the bacterial ribosomal protein bL36 family
PXO_00891	COG0539	negative regulation of cytoplasmic translation
PXO_00894	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
PXO_00895	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PXO_00897	COG1210	Utp--glucose-1-phosphate uridylyltransferase
PXO_00899	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PXO_00899	COG0475	glutathione-regulated potassium exporter activity
PXO_00906	COG0519	Catalyzes the synthesis of GMP from XMP
PXO_00906	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PXO_00908	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
PXO_00909	COG0583	DNA-binding transcription factor activity
PXO_00912	COG0583	DNA-binding transcription factor activity
PXO_00916	COG2201	protein-glutamate methylesterase activity
PXO_00917	COG1914	H( )-stimulated, divalent metal cation uptake system
PXO_00918	COG1321	iron dependent repressor
PXO_00919	COG0590	tRNA wobble adenosine to inosine editing
PXO_00921	COG0668	transmembrane transport
PXO_00923	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
PXO_00926	COG1028	Short-chain dehydrogenase reductase Sdr
PXO_00927	COG1183	phosphatidylcholine synthase activity
PXO_00929	COG3243	poly(R)-hydroxyalkanoic acid synthase
PXO_00932	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PXO_00937	COG2826	transposase and inactivated derivatives, IS30 family
PXO_00948	COG3209	COG3209 Rhs family protein
PXO_00950	COG2826	transposase and inactivated derivatives, IS30 family
PXO_00954	COG2198	Histidine kinase
PXO_00954	COG0643	Histidine kinase
PXO_00958	COG0455	bacterial-type flagellum organization
PXO_00961	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PXO_00965	COG5001	Diguanylate cyclase
PXO_00965	COG3300	MHYT domain
PXO_00967	COG5001	Diguanylate cyclase
PXO_00967	COG3300	MHYT domain
PXO_00968	COG1684	flagellar biosynthetic protein fliR
PXO_00969	COG1987	bacterial-type flagellum assembly
PXO_00972	COG3190	flagellar
PXO_00982	COG1677	Flagellar hook-basal body complex protein FliE
PXO_00988	COG1028	Short-chain dehydrogenase reductase Sdr
PXO_00990	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PXO_00993	COG2204	response regulator
PXO_00994	COG2201	protein-glutamate methylesterase activity
PXO_01000	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
PXO_01001	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PXO_01007	COG4786	Flagellar basal body rod
PXO_01008	COG4787	bacterial-type flagellum-dependent cell motility
PXO_01010	COG1749	Flagellar hook protein flgE
PXO_01011	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
PXO_01012	COG1558	bacterial-type flagellum-dependent cell motility
PXO_01013	COG1815	bacterial-type flagellum-dependent cell motility
PXO_01014	COG0784	Response regulator, receiver
PXO_01014	COG0835	chemotaxis
PXO_01018	COG5002	protein histidine kinase activity
PXO_01020	COG4585	Histidine kinase
PXO_01021	COG5001	Diguanylate cyclase
PXO_01026	COG0482	sulfurtransferase activity
PXO_01029	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
PXO_01030	COG0542	response to heat
PXO_01031	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PXO_01037	COG0492	ferredoxin-NADP+ reductase activity
PXO_01038	COG1674	ftsk spoiiie
PXO_01043	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
PXO_01048	COG0038	chloride channel
PXO_01049	COG0183	Belongs to the thiolase family
PXO_01050	COG1250	3-hydroxyacyl-CoA dehydrogenase
PXO_01050	COG1024	Enoyl-CoA hydratase
PXO_01052	COG0105	UTP biosynthetic process
PXO_01055	COG1426	Protein conserved in bacteria
PXO_01057	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PXO_01059	COG0303	'Molybdopterin
PXO_01072	COG2801	Transposase and inactivated derivatives
PXO_01074	COG2963	transposase activity
PXO_01080	COG3039	Transposase
PXO_01082	COG0583	DNA-binding transcription factor activity
PXO_01088	COG2801	Transposase and inactivated derivatives
PXO_01089	COG2801	Transposase and inactivated derivatives
PXO_01099	COG1278	Cold shock
PXO_01112	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PXO_01122	COG0750	zinc metalloprotease
PXO_01125	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
PXO_01126	COG0575	Belongs to the CDS family
PXO_01139	COG0024	Methionine aminopeptidase
PXO_01143	COG1393	Belongs to the ArsC family
PXO_01145	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PXO_01146	COG0367	asparagine synthase
PXO_01148	COG4774	siderophore transport
PXO_01153	COG2207	Transcriptional regulator
PXO_01156	COG1566	PFAM secretion protein HlyD family protein
PXO_01157	COG2814	Major facilitator Superfamily
PXO_01161	COG2801	Transposase and inactivated derivatives
PXO_01165	COG2826	transposase and inactivated derivatives, IS30 family
PXO_01173	COG1960	acyl-CoA dehydrogenase activity
PXO_01177	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
PXO_01179	COG2914	Belongs to the UPF0125 (RnfH) family
PXO_01180	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PXO_01182	COG0497	DNA recombination
PXO_01187	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
PXO_01188	COG0287	Prephenate dehydrogenase
PXO_01188	COG1605	Chorismate mutase
PXO_01191	COG0583	DNA-binding transcription factor activity
PXO_01193	COG1132	(ABC) transporter
PXO_01200	COG2850	peptidyl-arginine hydroxylation
PXO_01211	COG2826	transposase and inactivated derivatives, IS30 family
PXO_01220	COG1131	(ABC) transporter
PXO_01221	COG1725	Transcriptional regulator
PXO_01222	COG0386	Belongs to the glutathione peroxidase family
PXO_01230	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PXO_01232	COG1410	methionine synthase
PXO_01232	COG0646	methionine synthase
PXO_01233	COG0646	methionine synthase
PXO_01233	COG1410	methionine synthase
PXO_01235	COG1960	acyl-CoA dehydrogenase activity
PXO_01238	COG0557	exoribonuclease II activity
PXO_01241	COG0489	protein tyrosine kinase activity
PXO_01246	COG0412	Dienelactone hydrolase
PXO_01247	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PXO_01248	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PXO_01253	COG2826	transposase and inactivated derivatives, IS30 family
PXO_01254	COG0433	COG0433 Predicted ATPase
PXO_01259	COG2890	protein-(glutamine-N5) methyltransferase activity
PXO_01261	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PXO_01262	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PXO_01270	COG0133	tryptophan synthase activity
PXO_01272	COG0159	tryptophan synthase activity
PXO_01284	COG1028	Short-chain dehydrogenase reductase Sdr
PXO_01287	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PXO_01291	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
PXO_01292	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
PXO_01293	COG1034	ATP synthesis coupled electron transport
PXO_01294	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
PXO_01297	COG0713	ATP synthesis coupled electron transport
PXO_01300	COG1007	ATP synthesis coupled electron transport
PXO_01302	COG0195	Participates in both transcription termination and antitermination
PXO_01303	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PXO_01306	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PXO_01314	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
PXO_01315	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
PXO_01317	COG2095	MarC family integral membrane protein
PXO_01319	COG1611	Belongs to the LOG family
PXO_01355	COG3179	chitinase
PXO_01364	COG4695	Portal protein
PXO_01370	COG3039	Transposase
PXO_01374	COG0556	nucleotide-excision repair
PXO_01379	COG2963	transposase activity
PXO_01384	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PXO_01385	COG0291	Belongs to the bacterial ribosomal protein bL35 family
PXO_01386	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PXO_01387	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PXO_01389	COG0776	regulation of translation
PXO_01398	COG0438	transferase activity, transferring glycosyl groups
PXO_01399	COG0438	transferase activity, transferring glycosyl groups
PXO_01421	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PXO_01426	COG4191	Histidine kinase
PXO_01426	COG0784	Response regulator, receiver
PXO_01431	COG0552	protein localization to endoplasmic reticulum
PXO_01435	COG3938	Belongs to the proline racemase family
PXO_01436	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PXO_01439	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PXO_01441	COG0006	proline dipeptidase activity
PXO_01444	COG0531	amino acid
PXO_01457	COG4206	TonB-dependent receptor
PXO_01463	COG3328	transposase activity
PXO_01478	COG0746	molybdenum cofactor guanylyltransferase activity
PXO_01486	COG1648	precorrin-2 dehydrogenase activity
PXO_01486	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PXO_01500	COG3039	Transposase
PXO_01501	COG3039	Transposase
PXO_01511	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
PXO_01517	COG1530	ribonuclease E activity
PXO_01519	COG3064	Membrane
PXO_01520	COG0428	transporter
PXO_01521	COG0428	transporter
PXO_01523	COG2154	pterin-4-alpha-carbinolamine dehydratase
PXO_01524	COG0316	Belongs to the HesB IscA family
PXO_01524	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
PXO_01531	COG3501	Rhs element vgr protein
PXO_01538	COG2963	transposase activity
PXO_01541	COG2801	Transposase and inactivated derivatives
PXO_01543	COG2963	transposase activity
PXO_01548	COG0477	Major facilitator Superfamily
PXO_01552	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
PXO_01555	COG0217	transcriptional regulatory protein
PXO_01556	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
PXO_01560	COG0824	Thioesterase
PXO_01562	COG0848	biopolymer transport protein
PXO_01564	COG0823	Involved in the tonB-independent uptake of proteins
PXO_01565	COG2885	chlorophyll binding
PXO_01567	COG0602	queuosine metabolic process
PXO_01576	COG0514	ATP-dependent DNA helicase (RecQ)
PXO_01577	COG0783	Belongs to the Dps family
PXO_01578	COG1643	Atp-dependent helicase
PXO_01580	COG0837	glucose binding
PXO_01581	COG0837	glucose binding
PXO_01582	COG0837	glucose binding
PXO_01588	COG0535	radical SAM domain protein
PXO_01589	COG0535	radical SAM domain protein
PXO_01590	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
PXO_01592	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PXO_01595	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PXO_01597	COG1199	ATP-dependent helicase activity
PXO_01599	COG1397	ADP-ribosylglycohydrolase
PXO_01601	COG0189	ligase activity
PXO_01604	COG0835	chemotaxis
PXO_01605	COG0840	transmembrane signaling receptor activity
PXO_01616	COG2304	oxidoreductase activity
PXO_01618	COG1446	asparaginase
PXO_01619	COG3142	Participates in the control of copper homeostasis
PXO_01627	COG3537	Alpha-1,2-mannosidase
PXO_01638	COG1472	Belongs to the glycosyl hydrolase 3 family
PXO_01641	COG3525	Glycosyl hydrolase, family 20, catalytic domain
PXO_01642	COG3858	chitin binding
PXO_01642	COG1388	LysM domain
PXO_01645	COG0837	glucose binding
PXO_01646	COG1385	rRNA (uridine-N3-)-methyltransferase activity
PXO_01648	COG0494	nUDIX hydrolase
PXO_01650	COG3956	TIGRFAM MazG family protein
PXO_01652	COG0330	HflC and HflK could
PXO_01654	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PXO_01663	COG1960	acyl-CoA dehydrogenase activity
PXO_01665	COG1309	transcriptional regulator
PXO_01666	COG4771	TonB-dependent receptor
PXO_01668	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PXO_01670	COG0463	Glycosyl transferase, family 2
PXO_01671	COG0517	IMP dehydrogenase activity
PXO_01671	COG0516	GMP reductase activity
PXO_01677	COG1272	protein, Hemolysin III
PXO_01678	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PXO_01679	COG0739	heme binding
PXO_01680	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PXO_01681	COG0626	cystathionine gamma-synthase activity
PXO_01682	COG0527	aspartate kinase activity
PXO_01682	COG0460	homoserine dehydrogenase
PXO_01684	COG1760	l-serine dehydratase
PXO_01687	COG2353	YceI-like domain
PXO_01689	COG2353	YceI-like domain
PXO_01704	COG1960	acyl-CoA dehydrogenase activity
PXO_01705	COG1024	Enoyl-CoA hydratase
PXO_01709	COG1250	3-hydroxyacyl-CoA dehydrogenase
PXO_01709	COG1024	Enoyl-CoA hydratase
PXO_01713	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PXO_01714	COG0481	GTPase activity
PXO_01724	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
PXO_01726	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
PXO_01727	COG3046	protein related to deoxyribodipyrimidine photolyase
PXO_01730	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
PXO_01731	COG1278	Cold shock
PXO_01735	COG1201	RNA secondary structure unwinding
PXO_01736	COG1793	dna ligase
PXO_01738	COG1793	dna ligase
PXO_01738	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
PXO_01741	COG0745	RESPONSE REGULATOR receiver
PXO_01741	COG3706	GGDEF domain
PXO_01744	COG0183	Belongs to the thiolase family
PXO_01747	COG1451	nucleotide metabolic process
PXO_01750	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PXO_01751	COG3039	Transposase
PXO_01757	COG1047	Peptidyl-prolyl cis-trans
PXO_01761	COG2824	Alkylphosphonate utilization operon protein PhnA
PXO_01763	COG1902	pentaerythritol trinitrate reductase activity
PXO_01764	COG2814	Major facilitator Superfamily
PXO_01770	COG0392	lysyltransferase activity
PXO_01770	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PXO_01773	COG0251	oxidation-reduction process
PXO_01774	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PXO_01777	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PXO_01782	COG1595	DNA-templated transcription, initiation
PXO_01788	COG2878	Part of a membrane complex involved in electron transport
PXO_01792	COG0346	lactoylglutathione lyase activity
PXO_01794	COG0833	amino acid
PXO_01795	COG2040	homocysteine
PXO_01798	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
PXO_01818	COG1131	(ABC) transporter
PXO_01819	COG4771	TonB-dependent receptor
PXO_01826	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PXO_01828	COG2272	Belongs to the type-B carboxylesterase lipase family
PXO_01831	COG1970	mechanosensitive ion channel activity
PXO_01834	COG2826	transposase and inactivated derivatives, IS30 family
PXO_01839	COG0471	metal ion transport
PXO_01839	COG3273	potassium ion transport
PXO_01847	COG2963	transposase activity
PXO_01854	COG2826	transposase and inactivated derivatives, IS30 family
PXO_01858	COG3039	Transposase
PXO_01862	COG3039	Transposase
PXO_01872	COG3118	belongs to the thioredoxin family
PXO_01874	COG0495	leucyl-tRNA aminoacylation
PXO_01877	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PXO_01885	COG2968	Membrane
PXO_01887	COG1530	ribonuclease E activity
PXO_01889	COG3164	Protein of unknown function
PXO_01891	COG0312	modulator of DNA gyrase
PXO_01892	COG3028	Belongs to the UPF0307 family
PXO_01893	COG0312	modulator of DNA gyrase
PXO_01897	COG0142	geranyltranstransferase activity
PXO_01899	COG0037	tRNA processing
PXO_01900	COG1785	Belongs to the alkaline phosphatase family
PXO_01901	COG1301	dicarboxylic acid transport
PXO_01906	COG0791	NLP P60 protein
PXO_01907	COG0791	NLP P60 protein
PXO_01908	COG1047	Peptidyl-prolyl cis-trans
PXO_01909	COG2311	Membrane
PXO_01910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PXO_01912	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PXO_01920	COG0308	aminopeptidase N
PXO_01921	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PXO_01924	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
PXO_01927	COG0019	diaminopimelate decarboxylase activity
PXO_01929	COG2814	Major facilitator Superfamily
PXO_01930	COG4264	IucA IucC family
PXO_01932	COG4772	TonB-dependent receptor
PXO_01934	COG2963	transposase activity
PXO_01936	COG4651	solute:proton antiporter activity
PXO_01936	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PXO_01943	COG0488	(ABC) transporter
PXO_01948	COG2755	lipolytic protein G-D-S-L family
PXO_01948	COG0657	acetylesterase activity
PXO_01953	COG2207	Transcriptional regulator
PXO_01954	COG0326	Molecular chaperone. Has ATPase activity
PXO_01959	COG2963	transposase activity
PXO_01962	COG3328	transposase activity
PXO_01963	COG0174	glutamine synthetase
PXO_01965	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
PXO_01973	COG3039	Transposase
PXO_01976	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PXO_01977	COG0719	Fe-S assembly protein
PXO_01978	COG0396	ATPase activity
PXO_01979	COG0719	Fe-S assembly protein
PXO_01980	COG1959	2 iron, 2 sulfur cluster binding
PXO_01983	COG0693	protein deglycase activity
PXO_01992	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PXO_01997	COG0519	Catalyzes the synthesis of GMP from XMP
PXO_02004	COG1764	response to oxidative stress
PXO_02007	COG0384	phenazine biosynthesis protein PhzF
PXO_02010	COG0527	aspartate kinase activity
PXO_02016	COG0142	geranyltranstransferase activity
PXO_02018	COG0629	single-stranded DNA binding
PXO_02019	COG2203	Gaf domain
PXO_02019	COG3706	GGDEF domain
PXO_02019	COG4251	negative regulation of phosphorylation
PXO_02019	COG5001	Diguanylate cyclase
PXO_02025	COG2879	small protein
PXO_02026	COG1966	Carbon starvation protein
PXO_02027	COG1741	Belongs to the pirin family
PXO_02029	COG3501	Rhs element vgr protein
PXO_02036	COG3501	Rhs element vgr protein
PXO_02038	COG3501	Rhs element vgr protein
PXO_02039	COG3179	chitinase
PXO_02040	COG3501	Rhs element vgr protein
PXO_02054	COG3501	Rhs element vgr protein
PXO_02066	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
PXO_02083	COG0406	alpha-ribazole phosphatase activity
PXO_02083	COG0328	RNA-DNA hybrid ribonuclease activity
PXO_02084	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
PXO_02085	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
PXO_02092	COG0587	DNA-directed DNA polymerase activity
PXO_02096	COG1297	OPT oligopeptide transporter protein
PXO_02099	COG0823	Involved in the tonB-independent uptake of proteins
PXO_02099	COG1506	peptidase
PXO_02106	COG1917	Cupin 2, conserved barrel domain protein
PXO_02106	COG2207	Transcriptional regulator
PXO_02109	COG0753	catalase activity
PXO_02116	COG0126	phosphoglycerate kinase activity
PXO_02118	COG0469	pyruvate kinase activity
PXO_02119	COG3588	fructose-bisphosphate aldolase
PXO_02120	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
PXO_02127	COG0784	Response regulator, receiver
PXO_02127	COG2205	protein histidine kinase activity
PXO_02127	COG2198	Histidine kinase
PXO_02133	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PXO_02135	COG0529	Catalyzes the synthesis of activated sulfate
PXO_02135	COG2895	sulfate adenylyltransferase (ATP) activity
PXO_02143	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PXO_02148	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PXO_02151	COG0534	Mate efflux family protein
PXO_02158	COG0542	response to heat
PXO_02166	COG4206	TonB-dependent receptor
PXO_02175	COG2826	transposase and inactivated derivatives, IS30 family
PXO_02179	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
PXO_02181	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PXO_02185	COG1842	Phage shock protein A
PXO_02190	COG0754	glutathionylspermidine amidase activity
PXO_02196	COG0789	Transcriptional regulator
PXO_02208	COG0531	amino acid
PXO_02209	COG2197	response regulator
PXO_02211	COG1113	amino acid transport
PXO_02214	COG1271	oxidase subunit
PXO_02215	COG1294	oxidase, subunit
PXO_02217	COG2239	Acts as a magnesium transporter
PXO_02219	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PXO_02220	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PXO_02225	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PXO_02228	COG1137	ATPase activity
PXO_02229	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
PXO_02231	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
PXO_02233	COG0271	Belongs to the BolA IbaG family
PXO_02238	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PXO_02243	COG0628	permease
PXO_02245	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
PXO_02246	COG3178	'Phosphotransferase
PXO_02249	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PXO_02250	COG1555	photosystem II stabilization
PXO_02262	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PXO_02272	COG2201	protein-glutamate methylesterase activity
PXO_02277	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
PXO_02293	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PXO_02294	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PXO_02301	COG3039	Transposase
PXO_02303	COG0745	RESPONSE REGULATOR receiver
PXO_02304	COG3039	Transposase
PXO_02305	COG2205	protein histidine kinase activity
PXO_02308	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PXO_02317	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PXO_02317	COG3453	Protein conserved in bacteria
PXO_02318	COG0725	ABC transporter, periplasmic molybdate-binding protein
PXO_02319	COG4149	molybdate abc transporter
PXO_02320	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
PXO_02325	COG0642	Histidine kinase
PXO_02326	COG0745	RESPONSE REGULATOR receiver
PXO_02331	COG1022	Amp-dependent synthetase and ligase
PXO_02338	COG1376	ErfK ybiS ycfS ynhG family protein
PXO_02339	COG0739	heme binding
PXO_02340	COG4773	Receptor
PXO_02341	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PXO_02342	COG1301	dicarboxylic acid transport
PXO_02344	COG2304	oxidoreductase activity
PXO_02348	COG0714	Associated with various cellular activities
PXO_02356	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
PXO_02360	COG0254	rRNA binding
PXO_02362	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PXO_02364	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PXO_02368	COG1561	YicC-like family, N-terminal region
PXO_02372	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PXO_02378	COG0006	proline dipeptidase activity
PXO_02382	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PXO_02384	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PXO_02386	COG2912	Transglutaminase-like superfamily
PXO_02387	COG1773	rubredoxin
PXO_02388	COG0352	thiamine-phosphate diphosphorylase activity
PXO_02391	COG2801	Transposase and inactivated derivatives
PXO_02393	COG2963	transposase activity
PXO_02395	COG0281	malic enzyme
PXO_02395	COG0280	phosphate acetyltransferase
PXO_02398	COG4191	Histidine kinase
PXO_02400	COG0583	DNA-binding transcription factor activity
PXO_02404	COG2197	response regulator
PXO_02405	COG1840	ABC-type Fe3 transport system, periplasmic component
PXO_02406	COG0642	Histidine kinase
PXO_02410	COG2851	Citrate transporter
PXO_02411	COG1028	Short-chain dehydrogenase reductase Sdr
PXO_02412	COG1609	Transcriptional regulator
PXO_02413	COG2211	Major facilitator Superfamily
PXO_02419	COG1162	GTPase activity
PXO_02423	COG0726	polysaccharide deacetylase
PXO_02424	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
PXO_02433	COG0242	peptide deformylase activity
PXO_02436	COG0714	Associated with various cellular activities
PXO_02440	COG0537	adenosine 5'-monophosphoramidase activity
PXO_02445	COG0314	molybdopterin synthase activity
PXO_02446	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
PXO_02449	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PXO_02450	COG1234	tRNA 3'-trailer cleavage
PXO_02452	COG0859	PFAM glycosyl transferase family 9
PXO_02454	COG0582	viral genome integration into host DNA
PXO_02464	COG3501	Rhs element vgr protein
PXO_02467	COG0631	protein serine/threonine phosphatase activity
PXO_02468	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PXO_02473	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PXO_02476	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PXO_02477	COG0740	serine-type endopeptidase activity
PXO_02478	COG0544	peptidyl-prolyl cis-trans isomerase activity
PXO_02480	COG1484	DNA-dependent DNA replication
PXO_02483	COG2963	transposase activity
PXO_02485	COG0473	3-isopropylmalate dehydrogenase activity
PXO_02491	COG4783	chaperone-mediated protein folding
PXO_02495	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PXO_02497	COG0438	transferase activity, transferring glycosyl groups
PXO_02498	COG0671	phosphoesterase, PA-phosphatase related
PXO_02501	COG3291	Pkd domain containing protein
PXO_02503	COG2833	Protein of unknown function (DUF455)
PXO_02507	COG0285	dihydrofolate synthase activity
PXO_02509	COG0406	alpha-ribazole phosphatase activity
PXO_02515	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
PXO_02516	COG4208	sulfate ABC transporter
PXO_02517	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
PXO_02518	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
PXO_02519	COG0156	8-amino-7-oxononanoate synthase activity
PXO_02526	COG1902	pentaerythritol trinitrate reductase activity
PXO_02526	COG0446	pyridine nucleotide-disulphide oxidoreductase
PXO_02528	COG2963	transposase activity
PXO_02530	COG2801	Transposase and inactivated derivatives
PXO_02535	COG0584	glycerophosphoryl diester phosphodiesterase
PXO_02544	COG0625	glutathione transferase activity
PXO_02545	COG0039	L-malate dehydrogenase activity
PXO_02546	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PXO_02551	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
PXO_02555	COG2963	transposase activity
PXO_02572	COG2963	transposase activity
PXO_02575	COG0564	pseudouridine synthase activity
PXO_02585	COG3781	membrane
PXO_02587	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PXO_02598	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
PXO_02602	COG3710	Transcriptional regulator
PXO_02611	COG2226	methyltransferase
PXO_02615	COG3706	GGDEF domain
PXO_02620	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
PXO_02621	COG1538	Outer membrane efflux protein
PXO_02622	COG1519	Transferase
PXO_02623	COG1560	Kdo2-lipid A biosynthetic process
PXO_02632	COG0308	aminopeptidase N
PXO_02633	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PXO_02635	COG0330	HflC and HflK could
PXO_02636	COG0330	HflC and HflK could
PXO_02641	COG0678	peroxiredoxin activity
PXO_02652	COG2801	Transposase and inactivated derivatives
PXO_02657	COG0525	valine-tRNA ligase activity
PXO_02662	COG0795	lipopolysaccharide-transporting ATPase activity
PXO_02665	COG4974	Belongs to the 'phage' integrase family
PXO_02667	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PXO_02669	COG0047	phosphoribosylformylglycinamidine synthase activity
PXO_02669	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PXO_02671	COG5295	Hep Hag repeat protein
PXO_02673	COG1404	Belongs to the peptidase S8 family
PXO_02675	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PXO_02677	COG1459	type II secretion system
PXO_02678	COG2165	general secretion pathway protein
PXO_02679	COG4970	Tfp pilus assembly protein FimT
PXO_02680	COG2165	general secretion pathway protein
PXO_02681	COG4795	General secretion pathway protein
PXO_02682	COG3156	type II secretion system protein K
PXO_02683	COG3166	PFAM Fimbrial assembly family protein
PXO_02686	COG1450	Type ii and iii secretion system protein
PXO_02688	COG2188	Transcriptional regulator
PXO_02695	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PXO_02696	COG1518	maintenance of DNA repeat elements
PXO_02704	COG1399	metal-binding, possibly nucleic acid-binding protein
PXO_02709	COG1028	Short-chain dehydrogenase reductase Sdr
PXO_02712	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PXO_02713	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PXO_02717	COG3829	transcription factor binding
PXO_02726	COG2828	Protein conserved in bacteria
PXO_02738	COG3039	Transposase
PXO_02742	COG2963	transposase activity
PXO_02746	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PXO_02747	COG3265	gluconokinase activity
PXO_02748	COG2211	Major facilitator Superfamily
PXO_02749	COG3459	Glycosyltransferase 36 associated
PXO_02752	COG2205	protein histidine kinase activity
PXO_02755	COG1414	Transcriptional regulator
PXO_02756	COG0738	Major facilitator superfamily
PXO_02757	COG3254	rhamnose metabolic process
PXO_02761	COG0339	signal peptide processing
PXO_02767	COG0564	pseudouridine synthase activity
PXO_02772	COG1181	Belongs to the D-alanine--D-alanine ligase family
PXO_02788	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PXO_02790	COG0842	Transport permease protein
PXO_02791	COG1131	(ABC) transporter
PXO_02792	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PXO_02797	COG1476	TRANSCRIPTIONal
PXO_02799	COG4555	ABC transporter
PXO_02807	COG0625	glutathione transferase activity
PXO_02817	COG0583	DNA-binding transcription factor activity
PXO_02825	COG1199	ATP-dependent helicase activity
PXO_02828	COG1566	PFAM secretion protein HlyD family protein
PXO_02834	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PXO_02836	COG0745	RESPONSE REGULATOR receiver
PXO_02837	COG2205	protein histidine kinase activity
PXO_02840	COG3228	Belongs to the MtfA family
PXO_02842	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
PXO_02842	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
PXO_02853	COG3237	CsbD-like
PXO_02854	COG0180	Tryptophanyl-tRNA synthetase
PXO_02855	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PXO_02864	COG0753	catalase activity
PXO_02865	COG1595	DNA-templated transcription, initiation
PXO_02867	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PXO_02869	COG0628	permease
PXO_02872	COG1040	competence protein
PXO_02878	COG1028	Short-chain dehydrogenase reductase Sdr
PXO_02881	COG0463	Glycosyl transferase, family 2
PXO_02883	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PXO_02884	COG3100	YcgL domain-containing protein
PXO_02887	COG3387	PFAM Glycoside hydrolase 15-related
PXO_02888	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PXO_02891	COG2239	Acts as a magnesium transporter
PXO_02893	COG1042	CoA-binding domain protein
PXO_02893	COG0045	succinate-CoA ligase (ADP-forming) activity
PXO_02893	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PXO_02897	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PXO_02898	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PXO_02901	COG2963	transposase activity
PXO_02904	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
PXO_02906	COG3485	protocatechuate 3,4-dioxygenase
PXO_02907	COG3485	protocatechuate 3,4-dioxygenase
PXO_02909	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PXO_02910	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PXO_02912	COG1414	Transcriptional regulator
PXO_02914	COG2826	transposase and inactivated derivatives, IS30 family
PXO_02915	COG4221	oxidoreductase activity
PXO_02918	COG0018	arginyl-trna synthetase
PXO_02919	COG2003	Belongs to the UPF0758 family
PXO_02920	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PXO_02921	COG0756	dUTP diphosphatase activity
PXO_02925	COG0463	Glycosyl transferase, family 2
PXO_02929	COG1475	DNA binding
PXO_02930	COG1192	Involved in chromosome partitioning
PXO_02934	COG0708	Exodeoxyribonuclease III
PXO_02935	COG2211	Major facilitator Superfamily
PXO_02939	COG0739	heme binding
PXO_02941	COG2801	Transposase and inactivated derivatives
PXO_02942	COG2963	transposase activity
PXO_02953	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
PXO_02956	COG2814	Major facilitator Superfamily
PXO_02961	COG1289	transmembrane transporter activity
PXO_02964	COG0151	Belongs to the GarS family
PXO_02965	COG0138	bifunctional purine biosynthesis protein purh
PXO_02969	COG2267	carboxylic ester hydrolase activity
PXO_02970	COG2267	carboxylic ester hydrolase activity
PXO_02972	COG0671	phosphoesterase, PA-phosphatase related
PXO_02972	COG2453	phosphatase
PXO_02975	COG2831	hemolysin activation secretion protein
PXO_02976	COG3210	domain, Protein
PXO_02980	COG2963	transposase activity
PXO_02983	COG3039	Transposase
PXO_02989	COG2963	transposase activity
PXO_02996	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
PXO_03004	COG0439	Biotin carboxylase
PXO_03006	COG0511	ligase activity, forming carbon-carbon bonds
PXO_03011	COG1324	tolerance protein
PXO_03016	COG2826	transposase and inactivated derivatives, IS30 family
PXO_03019	COG1271	oxidase subunit
PXO_03025	COG2963	transposase activity
PXO_03032	COG2972	Histidine kinase
PXO_03033	COG3279	Response regulator of the LytR AlgR family
PXO_03036	COG0531	amino acid
PXO_03039	COG3590	peptidase
PXO_03042	COG0667	Aldo Keto reductase
PXO_03046	COG3384	dioxygenase
PXO_03048	COG1573	uracil-dna glycosylase
PXO_03050	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
PXO_03053	COG0025	NhaP-type Na H and K H
PXO_03054	COG1131	(ABC) transporter
PXO_03055	COG0842	Transport permease protein
PXO_03059	COG1404	Belongs to the peptidase S8 family
PXO_03072	COG1522	sequence-specific DNA binding
PXO_03073	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PXO_03078	COG2205	protein histidine kinase activity
PXO_03078	COG2202	Pas domain
PXO_03082	COG2813	Specifically methylates the guanine in position
PXO_03083	COG1187	pseudouridine synthase activity
PXO_03084	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PXO_03092	COG0697	spore germination
PXO_03094	COG2011	ABC-type metal ion transport system permease component
PXO_03101	COG0508	dehydrogenase complex catalyzes the overall conversion of
PXO_03103	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PXO_03107	COG0356	it plays a direct role in the translocation of protons across the membrane
PXO_03110	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PXO_03114	COG0355	proton-transporting ATP synthase activity, rotational mechanism
PXO_03123	COG3842	ATPase activity
PXO_03125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PXO_03126	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
PXO_03135	COG0339	signal peptide processing
PXO_03142	COG1956	GAF domain-containing protein
PXO_03145	COG0720	synthase
PXO_03147	COG0513	Belongs to the DEAD box helicase family
PXO_03149	COG0625	glutathione transferase activity
PXO_03157	COG0626	cystathionine gamma-synthase activity
PXO_03164	COG3328	transposase activity
PXO_03168	COG2086	electron transfer activity
PXO_03173	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
PXO_03173	COG0662	Cupin 2, conserved barrel domain protein
PXO_03174	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PXO_03181	COG3218	ABC-type transport auxiliary lipoprotein component
PXO_03181	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
PXO_03182	COG1127	ABC transporter
PXO_03183	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PXO_03188	COG1183	phosphatidylcholine synthase activity
PXO_03194	COG3039	Transposase
PXO_03197	COG2963	transposase activity
PXO_03206	COG2853	Lipoprotein
PXO_03209	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
PXO_03210	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PXO_03211	COG1127	ABC transporter
PXO_03223	COG0386	Belongs to the glutathione peroxidase family
PXO_03225	COG1322	Protein conserved in bacteria
PXO_03227	COG0531	amino acid
PXO_03230	COG0210	DNA helicase
PXO_03233	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PXO_03234	COG0583	DNA-binding transcription factor activity
PXO_03235	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PXO_03238	COG2159	amidohydrolase
PXO_03239	COG0267	Belongs to the bacterial ribosomal protein bL33 family
PXO_03240	COG0227	Belongs to the bacterial ribosomal protein bL28 family
PXO_03243	COG0357	Ribosomal RNA small subunit methyltransferase G
PXO_03244	COG3540	Alkaline phosphatase
PXO_03246	COG2091	lysine biosynthetic process via aminoadipic acid
PXO_03249	COG0708	Exodeoxyribonuclease III
PXO_03252	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PXO_03253	COG3162	membrane
PXO_03261	COG3507	Belongs to the glycosyl hydrolase 43 family
PXO_03264	COG1028	Short-chain dehydrogenase reductase Sdr
PXO_03265	COG0179	Fumarylacetoacetate (FAA) hydrolase
PXO_03266	COG4948	Mandelate Racemase Muconate Lactonizing
PXO_03268	COG4807	Protein conserved in bacteria
PXO_03270	COG1643	Atp-dependent helicase
PXO_03272	COG1187	pseudouridine synthase activity
PXO_03274	COG0667	Aldo Keto reductase
PXO_03275	COG2130	NADP-dependent
PXO_03276	COG0656	L-ascorbic acid biosynthetic process
PXO_03279	COG2963	transposase activity
PXO_03283	COG2755	lipolytic protein G-D-S-L family
PXO_03285	COG3186	Phenylalanine-4-hydroxylase
PXO_03286	COG1522	sequence-specific DNA binding
PXO_03290	COG4773	Receptor
PXO_03296	COG1064	alcohol dehydrogenase
PXO_03298	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
PXO_03299	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
PXO_03301	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
PXO_03302	COG2826	transposase and inactivated derivatives, IS30 family
PXO_03307	COG0676	glucose-6-phosphate 1-epimerase activity
PXO_03311	COG3135	benzoate transporter
PXO_03312	COG3135	benzoate transporter
PXO_03314	COG2826	transposase and inactivated derivatives, IS30 family
PXO_03318	COG0493	'glutamate synthase
PXO_03319	COG0069	glutamate synthase activity
PXO_03319	COG0070	glutamate synthase
PXO_03319	COG0067	glutamate synthase
PXO_03333	COG1205	dead DEAH box helicase
PXO_03333	COG1111	helicase
PXO_03334	COG1272	protein, Hemolysin III
PXO_03339	COG2826	transposase and inactivated derivatives, IS30 family
PXO_03342	COG1136	(ABC) transporter
PXO_03352	COG0508	dehydrogenase complex catalyzes the overall conversion of
PXO_03357	COG3039	Transposase
PXO_03359	COG0513	Belongs to the DEAD box helicase family
PXO_03370	COG0702	epimerase
PXO_03374	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PXO_03376	COG0297	glycogen (starch) synthase activity
PXO_03378	COG0745	RESPONSE REGULATOR receiver
PXO_03378	COG3706	GGDEF domain
PXO_03380	COG2354	Protein conserved in bacteria
PXO_03381	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
PXO_03384	COG1511	domain protein
PXO_03384	COG3264	Mechanosensitive ion channel
PXO_03402	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PXO_03424	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PXO_03426	COG1090	epimerase
PXO_03428	COG3039	Transposase
PXO_03433	COG2826	transposase and inactivated derivatives, IS30 family
PXO_03443	COG0477	Major facilitator Superfamily
PXO_03449	COG3039	Transposase
PXO_03455	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PXO_03458	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
PXO_03462	COG1755	Isoprenylcysteine carboxyl methyltransferase
PXO_03464	COG3039	Transposase
PXO_03467	COG4772	TonB-dependent receptor
PXO_03470	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PXO_03472	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
PXO_03478	COG0501	Belongs to the peptidase M48B family
PXO_03480	COG0187	DNA topoisomerase II activity
PXO_03485	COG0230	Belongs to the bacterial ribosomal protein bL34 family
PXO_03487	COG0706	membrane insertase activity
PXO_03488	COG0726	polysaccharide deacetylase
PXO_03489	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PXO_03490	COG0671	phosphoesterase, PA-phosphatase related
PXO_03494	COG0584	glycerophosphoryl diester phosphodiesterase
PXO_03496	COG0861	Integral membrane protein TerC family
PXO_03498	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PXO_03502	COG2271	Major facilitator Superfamily
PXO_03503	COG1929	Belongs to the glycerate kinase type-1 family
PXO_03506	COG3237	CsbD-like
PXO_03531	COG0477	Major facilitator Superfamily
PXO_03535	COG0302	gtp cyclohydrolase
PXO_03536	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PXO_03544	COG2234	aminopeptidase activity
PXO_03546	COG4942	peptidase
PXO_03547	COG0793	Belongs to the peptidase S41A family
PXO_03553	COG1196	nuclear chromosome segregation
PXO_03561	COG2032	superoxide dismutase activity
PXO_03563	COG2032	superoxide dismutase activity
PXO_03564	COG2204	response regulator
PXO_03565	COG3852	Histidine kinase
PXO_03566	COG0004	ammonium transporteR
PXO_03567	COG0347	Belongs to the P(II) protein family
PXO_03568	COG0174	glutamine synthetase
PXO_03577	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PXO_03579	COG2062	phosphohistidine phosphatase, SixA
PXO_03580	COG0489	protein tyrosine kinase activity
PXO_03585	COG1396	sequence-specific DNA binding
PXO_03586	COG3550	peptidyl-serine autophosphorylation
PXO_03587	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
PXO_03588	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PXO_03591	COG1125	glycine betaine transport
PXO_03591	COG0517	IMP dehydrogenase activity
PXO_03594	COG1119	ATPase activity
PXO_03596	COG1752	Esterase of the alpha-beta hydrolase superfamily
PXO_03601	COG2801	Transposase and inactivated derivatives
PXO_03602	COG2963	transposase activity
PXO_03607	COG2937	Belongs to the GPAT DAPAT family
PXO_03615	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
PXO_03620	COG0210	DNA helicase
PXO_03624	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
PXO_03629	COG1028	Short-chain dehydrogenase reductase Sdr
PXO_03634	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PXO_03644	COG3501	Rhs element vgr protein
PXO_03648	COG1166	arginine decarboxylase activity
PXO_03657	COG0606	chelatase, subunit chli
PXO_03663	COG3328	transposase activity
PXO_03667	COG0366	Alpha amylase catalytic
PXO_03668	COG0366	Alpha amylase catalytic
PXO_03674	COG1609	Transcriptional regulator
PXO_03675	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
PXO_03676	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
PXO_03689	COG3386	PFAM SMP-30 Gluconolaconase
PXO_03699	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PXO_03701	COG4771	TonB-dependent receptor
PXO_03704	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PXO_03709	COG1252	NADH dehydrogenase
PXO_03710	COG2860	membrane
PXO_03711	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PXO_03713	COG2201	protein-glutamate methylesterase activity
PXO_03714	COG2177	Part of the ABC transporter FtsEX involved in
PXO_03715	COG2884	Cell division ATP-binding protein ftsE
PXO_03717	COG3118	belongs to the thioredoxin family
PXO_03719	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PXO_03724	COG0729	surface antigen
PXO_03725	COG2911	Protein conserved in bacteria
PXO_03734	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PXO_03737	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PXO_03748	COG1733	regulation of RNA biosynthetic process
PXO_03749	COG0702	epimerase
PXO_03759	COG0583	DNA-binding transcription factor activity
PXO_03760	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PXO_03762	COG2205	protein histidine kinase activity
PXO_03763	COG2205	protein histidine kinase activity
PXO_03764	COG0745	RESPONSE REGULATOR receiver
PXO_03768	COG1902	pentaerythritol trinitrate reductase activity
PXO_03769	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
PXO_03772	COG2814	Major facilitator Superfamily
PXO_03773	COG0583	DNA-binding transcription factor activity
PXO_03776	COG0084	hydrolase, TatD family'
PXO_03786	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
PXO_03790	COG2072	flavoprotein involved in K transport
PXO_03801	COG2826	transposase and inactivated derivatives, IS30 family
PXO_03804	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PXO_03805	COG1960	acyl-CoA dehydrogenase activity
PXO_03818	COG0523	cobalamin synthesis protein
PXO_03824	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PXO_03827	COG4771	TonB-dependent receptor
PXO_03828	COG0457	Tetratricopeptide repeat
PXO_03831	COG0752	glycyl-tRNA synthetase alpha subunit
PXO_03832	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PXO_03836	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PXO_03836	COG0519	Catalyzes the synthesis of GMP from XMP
PXO_03838	COG0805	protein transport
PXO_03840	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PXO_03842	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
PXO_03845	COG2974	May be involved in recombination
PXO_03846	COG0037	tRNA processing
PXO_03852	COG3661	Belongs to the glycosyl hydrolase 67 family
PXO_03854	COG4948	Mandelate Racemase Muconate Lactonizing
PXO_03856	COG1472	Belongs to the glycosyl hydrolase 3 family
PXO_03857	COG0246	Mannitol dehydrogenase
PXO_03861	COG3693	PFAM glycoside hydrolase, family 10
PXO_03863	COG3693	PFAM glycoside hydrolase, family 10
PXO_03868	COG2211	Major facilitator Superfamily
PXO_03877	COG4943	cyclic-guanylate-specific phosphodiesterase activity
PXO_03887	COG1846	Transcriptional regulator
PXO_03888	COG1764	response to oxidative stress
PXO_03904	COG3549	Plasmid maintenance system killer
PXO_03906	COG1074	ATP-dependent DNA helicase activity
PXO_03909	COG0778	Nitroreductase
PXO_03910	COG2353	YceI-like domain
PXO_03931	COG2963	transposase activity
PXO_03932	COG2801	Transposase and inactivated derivatives
PXO_03937	COG3039	Transposase
PXO_03943	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PXO_03949	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PXO_03950	COG0318	PFAM AMP-dependent synthetase and ligase
PXO_03953	COG0596	Alpha beta hydrolase
PXO_03956	COG3177	Filamentation induced by cAMP protein fic
PXO_03957	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PXO_03960	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
PXO_03966	COG4191	Histidine kinase
PXO_03967	COG0028	Belongs to the TPP enzyme family
PXO_03971	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PXO_03979	COG5383	Protein conserved in bacteria
PXO_03981	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PXO_03982	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PXO_03984	COG1473	amidohydrolase
PXO_03988	COG3328	transposase activity
PXO_03997	COG2801	Transposase and inactivated derivatives
PXO_03998	COG2963	transposase activity
PXO_04004	COG0134	indole-3-glycerol-phosphate synthase activity
PXO_04016	COG2963	transposase activity
PXO_04019	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
PXO_04022	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
PXO_04034	COG3039	Transposase
PXO_04038	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PXO_04042	COG0534	Mate efflux family protein
PXO_04043	COG0616	signal peptide processing
PXO_04045	COG1028	Short-chain dehydrogenase reductase Sdr
PXO_04049	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PXO_04049	COG1754	DNA topoisomerase type I activity
PXO_04053	COG0758	DNA mediated transformation
PXO_04054	COG1652	LysM domain
PXO_04055	COG0242	peptide deformylase activity
PXO_04057	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PXO_04057	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PXO_04067	COG1560	Kdo2-lipid A biosynthetic process
PXO_04069	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PXO_04082	COG2826	transposase and inactivated derivatives, IS30 family
PXO_04097	COG0358	DNA primase activity
PXO_04098	COG1295	ribonuclease BN
PXO_04100	COG1610	YqeY-like protein
PXO_04101	COG0828	Belongs to the bacterial ribosomal protein bS21 family
PXO_04103	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PXO_04105	COG2826	transposase and inactivated derivatives, IS30 family
PXO_04111	COG2133	pyrroloquinoline quinone binding
PXO_04112	COG4682	membrane
PXO_04118	COG0531	amino acid
PXO_04122	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
PXO_04132	COG1505	serine-type exopeptidase activity
PXO_04139	COG3275	phosphorelay sensor kinase activity
PXO_04143	COG3293	Transposase
PXO_04147	COG3706	GGDEF domain
PXO_04150	COG0659	secondary active sulfate transmembrane transporter activity
PXO_04151	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
PXO_04151	COG5297	Belongs to the glycosyl hydrolase family 6
PXO_04153	COG0840	transmembrane signaling receptor activity
PXO_04167	COG3039	Transposase
PXO_04171	COG0598	Magnesium transport protein CorA
PXO_04173	COG1113	amino acid transport
PXO_04176	COG5297	Belongs to the glycosyl hydrolase family 6
PXO_04177	COG4305	rare lipoprotein A
PXO_04178	COG0697	spore germination
PXO_04190	COG4221	oxidoreductase activity
PXO_04192	COG2801	Transposase and inactivated derivatives
PXO_04193	COG2963	transposase activity
PXO_04197	COG0456	acetyltransferase
PXO_04199	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
PXO_04206	COG3227	Zinc metalloprotease (Elastase)
PXO_04209	COG2111	Na H antiporter
PXO_04209	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
PXO_04210	COG1006	Multisubunit Na H antiporter MnhC subunit
PXO_04211	COG0651	ATP synthesis coupled electron transport
PXO_04213	COG2212	antiporter activity
PXO_04214	COG1320	monovalent cation:proton antiporter activity
PXO_04219	COG3104	oligopeptide transport
PXO_04222	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PXO_04225	COG0022	dehydrogenase e1 component
PXO_04244	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
PXO_04245	COG3023	N-Acetylmuramoyl-L-alanine amidase
PXO_04247	COG4948	Mandelate Racemase Muconate Lactonizing
PXO_04252	COG3409	Peptidoglycan-binding domain 1 protein
PXO_04252	COG5632	N-Acetylmuramoyl-L-alanine amidase
PXO_04252	COG1388	LysM domain
PXO_04253	COG3501	Rhs element vgr protein
PXO_04258	COG0772	Belongs to the SEDS family
PXO_04261	COG1792	Involved in formation and maintenance of cell shape
PXO_04262	COG1077	Cell shape determining protein MreB Mrl
PXO_04275	COG2199	diguanylate cyclase activity
PXO_04276	COG0308	aminopeptidase N
PXO_04282	COG2951	lytic endotransglycosylase activity
PXO_04283	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PXO_04285	COG1686	Belongs to the peptidase S11 family
PXO_04292	COG1056	cytidyltransferase-related domain
PXO_04292	COG1051	belongs to the nudix hydrolase family
PXO_04301	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
PXO_04302	COG0673	inositol 2-dehydrogenase activity
PXO_04303	COG2823	Periplasmic or secreted lipoprotein
PXO_04304	COG4251	negative regulation of phosphorylation
PXO_04305	COG0784	Response regulator, receiver
PXO_04306	COG4191	Histidine kinase
PXO_04307	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PXO_04310	COG2801	Transposase and inactivated derivatives
PXO_04312	COG2963	transposase activity
PXO_04316	COG3250	beta-galactosidase activity
PXO_04322	COG1609	Transcriptional regulator
PXO_04323	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
PXO_04324	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
PXO_04326	COG1215	transferase activity, transferring glycosyl groups
PXO_04327	COG0726	polysaccharide deacetylase
PXO_04327	COG1649	PFAM Uncharacterised BCR, COG1649
PXO_04339	COG2226	methyltransferase
PXO_04350	COG1028	Short-chain dehydrogenase reductase Sdr
PXO_04350	COG0604	alcohol dehydrogenase
PXO_04350	COG3321	synthase
PXO_04353	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
PXO_04356	COG0494	nUDIX hydrolase
PXO_04358	COG0653	protein targeting
PXO_04359	COG1388	LysM domain
PXO_04359	COG4942	peptidase
PXO_04362	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PXO_04364	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
PXO_04365	COG1181	Belongs to the D-alanine--D-alanine ligase family
PXO_04369	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PXO_04370	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PXO_04373	COG3116	cell division
PXO_04381	COG1988	membrane-bound metal-dependent
PXO_04382	COG0277	FAD linked oxidase domain protein
PXO_04383	COG0745	RESPONSE REGULATOR receiver
PXO_04384	COG2205	protein histidine kinase activity
PXO_04386	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
PXO_04387	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
PXO_04395	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
PXO_04401	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PXO_04401	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PXO_04409	COG0488	(ABC) transporter
PXO_04414	COG3791	Glutathione-dependent formaldehyde-activating
PXO_04421	COG0745	RESPONSE REGULATOR receiver
PXO_04422	COG2205	protein histidine kinase activity
PXO_04427	COG2205	protein histidine kinase activity
PXO_04436	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PXO_04438	COG2963	transposase activity
PXO_04439	COG3039	Transposase
PXO_04441	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PXO_04450	COG2963	transposase activity
PXO_04451	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PXO_04456	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
PXO_04459	COG2197	response regulator
PXO_04460	COG4585	Histidine kinase
PXO_04464	COG2894	cell division
PXO_04465	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
PXO_04467	COG0642	Histidine kinase
PXO_04469	COG0745	RESPONSE REGULATOR receiver
PXO_04470	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PXO_04472	COG2194	sulfuric ester hydrolase activity
PXO_04479	COG3551	Protein conserved in bacteria
PXO_04488	COG2801	Transposase and inactivated derivatives
PXO_04490	COG2963	transposase activity
PXO_04492	COG2826	transposase and inactivated derivatives, IS30 family
PXO_04495	COG0203	ribosomal protein L17
PXO_04496	COG0202	RNA polymerase activity
PXO_04499	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PXO_04500	COG0201	protein transport
PXO_04502	COG1841	ribosomal large subunit assembly
PXO_04503	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PXO_04504	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PXO_04508	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PXO_04510	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PXO_04512	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PXO_04513	COG0255	Belongs to the universal ribosomal protein uL29 family
PXO_04514	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PXO_04519	COG0089	rRNA binding
PXO_04528	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PXO_04533	COG0081	regulation of translation
PXO_04536	COG0250	Participates in transcription elongation, termination and antitermination
PXO_04537	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
PXO_04539	COG0012	GTP binding
PXO_04542	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PXO_04547	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
PXO_04550	COG0521	Mo-molybdopterin cofactor biosynthetic process
PXO_04554	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PXO_04560	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PXO_04561	COG1404	Belongs to the peptidase S8 family
PXO_04562	COG1404	Belongs to the peptidase S8 family
PXO_04566	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PXO_04570	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
PXO_04571	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
PXO_04576	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
PXO_04579	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PXO_04579	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PXO_04588	COG2890	protein-(glutamine-N5) methyltransferase activity
PXO_04590	COG3634	alkyl hydroperoxide reductase activity
PXO_04591	COG0583	DNA-binding transcription factor activity
PXO_04592	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PXO_04593	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PXO_04598	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PXO_04600	COG2197	response regulator
PXO_04603	COG3039	Transposase
PXO_04606	COG3706	GGDEF domain
PXO_04606	COG0745	RESPONSE REGULATOR receiver
PXO_04612	COG2826	transposase and inactivated derivatives, IS30 family
PXO_04617	COG0697	spore germination
PXO_04620	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
PXO_04622	COG3386	PFAM SMP-30 Gluconolaconase
PXO_04626	COG1024	Enoyl-CoA hydratase
PXO_04628	COG0318	PFAM AMP-dependent synthetase and ligase
PXO_04629	COG0583	DNA-binding transcription factor activity
PXO_04630	COG3384	dioxygenase
PXO_04637	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PXO_04638	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PXO_04640	COG2096	Adenosyltransferase
PXO_04641	COG0123	including yeast histone deacetylase and acetoin utilization protein
PXO_04644	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
PXO_04647	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PXO_04654	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
PXO_04658	COG0642	Histidine kinase
PXO_04661	COG4181	ATPase activity
PXO_04663	COG2175	clavaminate synthase activity
PXO_04668	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PXO_04673	COG0667	Aldo Keto reductase
PXO_04676	COG3039	Transposase
PXO_04679	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PXO_04680	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PXO_04682	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PXO_04683	COG4106	trans-aconitate 2-methyltransferase activity
PXO_04686	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PXO_04700	COG3501	Rhs element vgr protein
PXO_04702	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PXO_04707	COG3039	Transposase
PXO_04713	COG3501	Rhs element vgr protein
PXO_04714	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PXO_04718	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PXO_04722	COG3039	Transposase
PXO_04727	COG3039	Transposase
PXO_04736	COG3039	Transposase
PXO_04742	COG2205	protein histidine kinase activity
PXO_04743	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
PXO_04745	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PXO_04748	COG3039	Transposase
PXO_04751	COG0840	transmembrane signaling receptor activity
PXO_04752	COG0835	chemotaxis
PXO_04753	COG2200	EAL domain
PXO_04753	COG2199	diguanylate cyclase activity
PXO_04753	COG2202	Pas domain
PXO_04754	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
PXO_04756	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PXO_04757	COG3590	peptidase
PXO_04761	COG0588	phosphoglycerate mutase activity
PXO_04762	COG1515	deoxyribonuclease V activity
PXO_04763	COG1741	Belongs to the pirin family
PXO_04767	COG3039	Transposase
PXO_04792	COG1028	Short-chain dehydrogenase reductase Sdr
PXO_04795	COG0415	Belongs to the DNA photolyase family
PXO_04796	COG0305	Participates in initiation and elongation during chromosome replication
PXO_04798	COG0367	asparagine synthase
PXO_04805	COG1960	acyl-CoA dehydrogenase activity
PXO_04808	COG0084	hydrolase, TatD family'
PXO_04809	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
PXO_04819	COG0735	belongs to the Fur family
PXO_04826	COG5001	Diguanylate cyclase
PXO_04826	COG5002	protein histidine kinase activity
PXO_04827	COG1187	pseudouridine synthase activity
PXO_04834	COG0475	glutathione-regulated potassium exporter activity
PXO_04835	COG5002	protein histidine kinase activity
PXO_04835	COG5000	phosphorelay sensor kinase activity
PXO_04836	COG0745	RESPONSE REGULATOR receiver
PXO_04842	COG1132	(ABC) transporter
PXO_04845	COG3293	Transposase
PXO_04848	COG3039	Transposase
PXO_04849	COG3209	COG3209 Rhs family protein
PXO_04850	COG3039	Transposase
PXO_04856	COG1595	DNA-templated transcription, initiation
PXO_04867	COG1877	trehalose-phosphatase activity
PXO_04868	COG3387	PFAM Glycoside hydrolase 15-related
PXO_04873	COG0564	pseudouridine synthase activity
PXO_04874	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PXO_04876	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PXO_04876	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
PXO_04878	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
PXO_04885	COG2194	sulfuric ester hydrolase activity
PXO_04886	COG4969	Belongs to the N-Me-Phe pilin family
PXO_04888	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
PXO_04892	COG0824	Thioesterase
PXO_04893	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PXO_05418	COG3293	Transposase
PXO_05425	COG2826	transposase and inactivated derivatives, IS30 family
PXO_05437	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
PXO_05439	COG3293	Transposase
PXO_05443	COG3293	Transposase
PXO_05448	COG2963	transposase activity
PXO_05450	COG3293	Transposase
PXO_05463	COG3293	Transposase
PXO_05465	COG3293	Transposase
PXO_05466	COG3293	Transposase
PXO_05473	COG3293	Transposase
PXO_05485	COG3293	Transposase
PXO_05492	COG3791	Glutathione-dependent formaldehyde-activating
PXO_05501	COG3293	Transposase
PXO_05507	COG3293	Transposase
PXO_05513	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PXO_05516	COG3039	Transposase
PXO_05526	COG3039	Transposase
PXO_05531	COG1946	Acyl-CoA thioesterase
PXO_05538	COG3209	COG3209 Rhs family protein
PXO_05538	COG3209	COG3209 Rhs family protein
PXO_05545	COG3293	Transposase
PXO_05556	COG3293	Transposase
PXO_05573	COG3293	Transposase
PXO_05577	COG3039	Transposase
PXO_05583	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
PXO_05585	COG3293	Transposase
PXO_05593	COG2826	transposase and inactivated derivatives, IS30 family
PXO_05594	COG3293	Transposase
PXO_05595	COG3293	Transposase
PXO_05596	COG3293	Transposase
PXO_05606	COG3293	Transposase
PXO_05611	COG0140	phosphoribosyl-ATP diphosphatase activity
PXO_05611	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PXO_05617	COG0723	plastoquinol--plastocyanin reductase activity
PXO_05617	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PXO_05625	COG3039	Transposase
PXO_05631	COG3209	COG3209 Rhs family protein
PXO_05637	COG3328	transposase activity
PXO_05639	COG3039	Transposase
PXO_05641	COG3293	Transposase
PXO_05645	COG3293	Transposase
PXO_05659	COG3293	Transposase
PXO_05662	COG3293	Transposase
PXO_05663	COG3293	Transposase
PXO_05664	COG3293	Transposase
PXO_05679	COG3293	Transposase
PXO_05683	COG3293	Transposase
PXO_05685	COG3293	Transposase
PXO_05687	COG3293	Transposase
PXO_05688	COG3293	Transposase
PXO_05689	COG3039	Transposase
PXO_05698	COG2963	transposase activity
PXO_05705	COG2963	transposase activity
PXO_05714	COG2201	protein-glutamate methylesterase activity
PXO_05727	COG3293	Transposase
PXO_05736	COG3293	Transposase
PXO_05737	COG3293	Transposase
PXO_05738	COG3293	Transposase
PXO_05757	COG3293	Transposase
PXO_05777	COG2963	transposase activity
PXO_05778	COG3293	Transposase
PXO_05779	COG3293	Transposase
PXO_05783	COG3293	Transposase
PXO_05796	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PXO_05829	COG0617	tRNA 3'-terminal CCA addition
PXO_06050	COG1414	Transcriptional regulator
PXO_06055	COG2801	Transposase and inactivated derivatives
PXO_06061	COG0436	Aminotransferase
PXO_06074	COG0277	FAD linked oxidase domain protein
PXO_06075	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PXO_06077	COG0531	amino acid
PXO_06078	COG0531	amino acid
PXO_06079	COG0235	Class ii aldolase
PXO_06081	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
PXO_06088	COG3039	Transposase
PXO_06090	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PXO_06099	COG2826	transposase and inactivated derivatives, IS30 family
PXO_06107	COG0303	'Molybdopterin
PXO_06109	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PXO_06111	COG1426	Protein conserved in bacteria
PXO_06114	COG0105	UTP biosynthetic process
PXO_06116	COG1250	3-hydroxyacyl-CoA dehydrogenase
PXO_06116	COG1024	Enoyl-CoA hydratase
PXO_06117	COG0183	Belongs to the thiolase family
PXO_06118	COG0038	chloride channel
PXO_06123	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
PXO_06128	COG1674	ftsk spoiiie
PXO_06129	COG0492	ferredoxin-NADP+ reductase activity
PXO_06135	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PXO_06136	COG0542	response to heat
PXO_06137	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
PXO_06140	COG0482	sulfurtransferase activity
PXO_06145	COG5001	Diguanylate cyclase
PXO_06146	COG4585	Histidine kinase
PXO_06148	COG5002	protein histidine kinase activity
PXO_06152	COG0784	Response regulator, receiver
PXO_06152	COG0835	chemotaxis
PXO_06153	COG1815	bacterial-type flagellum-dependent cell motility
PXO_06154	COG1558	bacterial-type flagellum-dependent cell motility
PXO_06155	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
PXO_06156	COG1749	Flagellar hook protein flgE
PXO_06158	COG4787	bacterial-type flagellum-dependent cell motility
PXO_06159	COG4786	Flagellar basal body rod
PXO_06165	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PXO_06166	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
PXO_06172	COG2201	protein-glutamate methylesterase activity
PXO_06173	COG2204	response regulator
PXO_06176	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PXO_06178	COG1028	Short-chain dehydrogenase reductase Sdr
PXO_06184	COG1677	Flagellar hook-basal body complex protein FliE
PXO_06194	COG3190	flagellar
PXO_06197	COG1987	bacterial-type flagellum assembly
PXO_06198	COG1684	flagellar biosynthetic protein fliR
PXO_06199	COG3300	MHYT domain
PXO_06199	COG5001	Diguanylate cyclase
PXO_06201	COG3300	MHYT domain
PXO_06201	COG5001	Diguanylate cyclase
PXO_06205	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PXO_06208	COG0455	bacterial-type flagellum organization
PXO_06212	COG0643	Histidine kinase
PXO_06212	COG2198	Histidine kinase
PXO_06216	COG2826	transposase and inactivated derivatives, IS30 family
PXO_06218	COG3209	COG3209 Rhs family protein
PXO_06221	COG3209	COG3209 Rhs family protein
PXO_06225	COG2801	Transposase and inactivated derivatives
PXO_06226	COG2801	Transposase and inactivated derivatives
PXO_06237	COG0583	DNA-binding transcription factor activity
PXO_06239	COG3039	Transposase
PXO_06245	COG2963	transposase activity
PXO_06246	COG2801	Transposase and inactivated derivatives
PXO_06258	COG1278	Cold shock
PXO_06261	COG3328	transposase activity