locus-tag	class	description
LA08_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LA08_00025	COG0187	DNA topoisomerase II activity
LA08_00035	COG0501	Belongs to the peptidase M48B family
LA08_00075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LA08_00095	COG4772	TonB-dependent receptor
LA08_00110	COG3039	Transposase
LA08_00120	COG1755	Isoprenylcysteine carboxyl methyltransferase
LA08_00145	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LA08_00155	COG3039	Transposase
LA08_00160	COG1136	(ABC) transporter
LA08_00210	COG3039	Transposase
LA08_00220	COG0513	Belongs to the DEAD box helicase family
LA08_00325	COG1858	cytochrome C peroxidase
LA08_00335	COG0702	epimerase
LA08_00360	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LA08_00375	COG3706	GGDEF domain
LA08_00375	COG0745	RESPONSE REGULATOR receiver
LA08_00385	COG2354	Protein conserved in bacteria
LA08_00395	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LA08_00410	COG1511	domain protein
LA08_00410	COG3264	Mechanosensitive ion channel
LA08_00490	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LA08_00570	COG3039	Transposase
LA08_00580	COG3039	Transposase
LA08_00615	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LA08_00625	COG0642	Histidine kinase
LA08_00635	COG1090	epimerase
LA08_00645	COG3039	Transposase
LA08_00670	COG2826	transposase and inactivated derivatives, IS30 family
LA08_00730	COG1136	(ABC) transporter
LA08_00775	COG1272	protein, Hemolysin III
LA08_00780	COG1205	dead DEAH box helicase
LA08_00780	COG1111	helicase
LA08_00845	COG0070	glutamate synthase
LA08_00845	COG0069	glutamate synthase activity
LA08_00845	COG0067	glutamate synthase
LA08_00850	COG0493	'glutamate synthase
LA08_00900	COG1609	Transcriptional regulator
LA08_00935	COG0366	Alpha amylase catalytic
LA08_00940	COG0366	Alpha amylase catalytic
LA08_00995	COG0606	chelatase, subunit chli
LA08_01045	COG1166	arginine decarboxylase activity
LA08_01055	COG3501	Rhs element vgr protein
LA08_01135	COG1028	Short-chain dehydrogenase reductase Sdr
LA08_01160	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
LA08_01175	COG0210	DNA helicase
LA08_01195	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
LA08_01235	COG2937	Belongs to the GPAT DAPAT family
LA08_01265	COG2755	lipolytic protein G-D-S-L family
LA08_01280	COG3186	Phenylalanine-4-hydroxylase
LA08_01285	COG1522	sequence-specific DNA binding
LA08_01335	COG1064	alcohol dehydrogenase
LA08_01345	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LA08_01355	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LA08_01365	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LA08_01390	COG3039	Transposase
LA08_01395	COG0676	glucose-6-phosphate 1-epimerase activity
LA08_01485	COG2853	Lipoprotein
LA08_01500	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LA08_01505	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LA08_01510	COG1127	ABC transporter
LA08_01585	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LA08_01600	COG3265	gluconokinase activity
LA08_01605	COG2211	Major facilitator Superfamily
LA08_01610	COG3459	Glycosyltransferase 36 associated
LA08_01625	COG2205	protein histidine kinase activity
LA08_01635	COG1414	Transcriptional regulator
LA08_01640	COG0738	Major facilitator superfamily
LA08_01645	COG3254	rhamnose metabolic process
LA08_01675	COG0339	signal peptide processing
LA08_01705	COG0564	pseudouridine synthase activity
LA08_01815	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LA08_01825	COG0842	Transport permease protein
LA08_01830	COG1131	(ABC) transporter
LA08_01835	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LA08_01855	COG1476	TRANSCRIPTIONal
LA08_01865	COG4555	ABC transporter
LA08_01905	COG0625	glutathione transferase activity
LA08_01955	COG0583	DNA-binding transcription factor activity
LA08_01990	COG1199	ATP-dependent helicase activity
LA08_02010	COG1566	PFAM secretion protein HlyD family protein
LA08_02040	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LA08_02050	COG0745	RESPONSE REGULATOR receiver
LA08_02055	COG2205	protein histidine kinase activity
LA08_02080	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
LA08_02080	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
LA08_02140	COG3237	CsbD-like
LA08_02145	COG0180	Tryptophanyl-tRNA synthetase
LA08_02150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LA08_02200	COG0753	catalase activity
LA08_02205	COG1595	DNA-templated transcription, initiation
LA08_02215	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LA08_02225	COG0628	permease
LA08_02245	COG1040	competence protein
LA08_02270	COG1028	Short-chain dehydrogenase reductase Sdr
LA08_02285	COG0463	Glycosyl transferase, family 2
LA08_02295	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LA08_02300	COG3100	YcgL domain-containing protein
LA08_02315	COG3387	PFAM Glycoside hydrolase 15-related
LA08_02325	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LA08_02345	COG2239	Acts as a magnesium transporter
LA08_02355	COG1042	CoA-binding domain protein
LA08_02355	COG0045	succinate-CoA ligase (ADP-forming) activity
LA08_02355	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LA08_02365	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LA08_02375	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LA08_02410	COG3485	protocatechuate 3,4-dioxygenase
LA08_02415	COG3485	protocatechuate 3,4-dioxygenase
LA08_02430	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LA08_02435	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LA08_02465	COG4221	oxidoreductase activity
LA08_02490	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LA08_02515	COG0463	Glycosyl transferase, family 2
LA08_02530	COG1475	DNA binding
LA08_02535	COG1192	Involved in chromosome partitioning
LA08_02550	COG0708	Exodeoxyribonuclease III
LA08_02555	COG2211	Major facilitator Superfamily
LA08_02570	COG0739	heme binding
LA08_02660	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
LA08_02685	COG2814	Major facilitator Superfamily
LA08_02700	COG1289	transmembrane transporter activity
LA08_02710	COG1136	(ABC) transporter
LA08_02710	COG0577	efflux transmembrane transporter activity
LA08_02715	COG0151	Belongs to the GarS family
LA08_02725	COG0419	ATPase involved in DNA repair
LA08_02740	COG2267	carboxylic ester hydrolase activity
LA08_02750	COG2267	carboxylic ester hydrolase activity
LA08_02755	COG0671	phosphoesterase, PA-phosphatase related
LA08_02755	COG2453	phosphatase
LA08_02770	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
LA08_02830	COG0439	Biotin carboxylase
LA08_02840	COG0511	ligase activity, forming carbon-carbon bonds
LA08_02865	COG1324	tolerance protein
LA08_02900	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LA08_02930	COG0534	Mate efflux family protein
LA08_02935	COG0616	signal peptide processing
LA08_02945	COG1028	Short-chain dehydrogenase reductase Sdr
LA08_02965	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LA08_02965	COG1754	DNA topoisomerase type I activity
LA08_02985	COG0758	DNA mediated transformation
LA08_02990	COG1652	LysM domain
LA08_02995	COG0242	peptide deformylase activity
LA08_03005	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LA08_03005	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LA08_03055	COG1560	Kdo2-lipid A biosynthetic process
LA08_03065	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LA08_03220	COG1294	oxidase, subunit
LA08_03225	COG1271	oxidase subunit
LA08_03240	COG2204	response regulator
LA08_03270	COG2972	Histidine kinase
LA08_03285	COG0531	amino acid
LA08_03305	COG3590	peptidase
LA08_03320	COG0667	Aldo Keto reductase
LA08_03335	COG3384	dioxygenase
LA08_03345	COG1573	uracil-dna glycosylase
LA08_03355	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
LA08_03370	COG0025	NhaP-type Na H and K H
LA08_03375	COG1131	(ABC) transporter
LA08_03380	COG0842	Transport permease protein
LA08_03395	COG1404	Belongs to the peptidase S8 family
LA08_03410	COG0745	RESPONSE REGULATOR receiver
LA08_03455	COG1522	sequence-specific DNA binding
LA08_03460	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LA08_03485	COG2202	Pas domain
LA08_03485	COG2205	protein histidine kinase activity
LA08_03520	COG2813	Specifically methylates the guanine in position
LA08_03525	COG1187	pseudouridine synthase activity
LA08_03530	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LA08_03565	COG0697	spore germination
LA08_03575	COG2011	ABC-type metal ion transport system permease component
LA08_03605	COG0508	dehydrogenase complex catalyzes the overall conversion of
LA08_03615	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LA08_03635	COG0356	it plays a direct role in the translocation of protons across the membrane
LA08_03725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LA08_03730	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LA08_03785	COG0339	signal peptide processing
LA08_03825	COG1956	GAF domain-containing protein
LA08_03840	COG0720	synthase
LA08_03850	COG0513	Belongs to the DEAD box helicase family
LA08_03895	COG0626	cystathionine gamma-synthase activity
LA08_03945	COG3328	transposase activity
LA08_03970	COG2086	electron transfer activity
LA08_03995	COG0662	Cupin 2, conserved barrel domain protein
LA08_03995	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
LA08_04000	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LA08_04040	COG3218	ABC-type transport auxiliary lipoprotein component
LA08_04040	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LA08_04045	COG1127	ABC transporter
LA08_04050	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LA08_04075	COG1183	phosphatidylcholine synthase activity
LA08_04105	COG3039	Transposase
LA08_04175	COG0525	valine-tRNA ligase activity
LA08_04200	COG0795	lipopolysaccharide-transporting ATPase activity
LA08_04215	COG4974	Belongs to the 'phage' integrase family
LA08_04220	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LA08_04225	COG0047	phosphoribosylformylglycinamidine synthase activity
LA08_04225	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LA08_04235	COG5295	Hep Hag repeat protein
LA08_04255	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LA08_04265	COG1459	type II secretion system
LA08_04270	COG2165	general secretion pathway protein
LA08_04275	COG4970	Tfp pilus assembly protein FimT
LA08_04280	COG2165	general secretion pathway protein
LA08_04285	COG4795	General secretion pathway protein
LA08_04290	COG3156	type II secretion system protein K
LA08_04295	COG3166	PFAM Fimbrial assembly family protein
LA08_04310	COG1450	Type ii and iii secretion system protein
LA08_04325	COG2188	Transcriptional regulator
LA08_04380	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LA08_04385	COG1518	maintenance of DNA repeat elements
LA08_04430	COG1399	metal-binding, possibly nucleic acid-binding protein
LA08_04455	COG1028	Short-chain dehydrogenase reductase Sdr
LA08_04470	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LA08_04475	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LA08_04510	COG3829	transcription factor binding
LA08_04545	COG3039	Transposase
LA08_04595	COG2826	transposase and inactivated derivatives, IS30 family
LA08_04605	COG0678	peroxiredoxin activity
LA08_04625	COG0330	HflC and HflK could
LA08_04630	COG0330	HflC and HflK could
LA08_04645	COG0308	aminopeptidase N
LA08_04695	COG1560	Kdo2-lipid A biosynthetic process
LA08_04700	COG1519	Transferase
LA08_04705	COG1538	Outer membrane efflux protein
LA08_04710	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LA08_04790	COG3710	Transcriptional regulator
LA08_04815	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LA08_04835	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
LA08_04865	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LA08_04875	COG3781	membrane
LA08_04895	COG0625	glutathione transferase activity
LA08_04905	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LA08_04930	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
LA08_05065	COG3039	Transposase
LA08_05090	COG0584	glycerophosphoryl diester phosphodiesterase
LA08_05115	COG0473	3-isopropylmalate dehydrogenase activity
LA08_05170	COG0544	peptidyl-prolyl cis-trans isomerase activity
LA08_05175	COG0740	serine-type endopeptidase activity
LA08_05210	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LA08_05235	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LA08_05245	COG0631	protein serine/threonine phosphatase activity
LA08_05270	COG3501	Rhs element vgr protein
LA08_05330	COG0582	viral genome integration into host DNA
LA08_05340	COG0859	PFAM glycosyl transferase family 9
LA08_05350	COG1234	tRNA 3'-trailer cleavage
LA08_05355	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LA08_05370	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LA08_05375	COG0314	molybdopterin synthase activity
LA08_05405	COG0537	adenosine 5'-monophosphoramidase activity
LA08_05425	COG0714	Associated with various cellular activities
LA08_05445	COG0242	peptide deformylase activity
LA08_05495	COG3039	Transposase
LA08_05525	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LA08_05530	COG0726	polysaccharide deacetylase
LA08_05580	COG2211	Major facilitator Superfamily
LA08_05590	COG1609	Transcriptional regulator
LA08_05595	COG1028	Short-chain dehydrogenase reductase Sdr
LA08_05600	COG2851	Citrate transporter
LA08_05620	COG0642	Histidine kinase
LA08_05625	COG1840	ABC-type Fe3 transport system, periplasmic component
LA08_05630	COG2197	response regulator
LA08_05650	COG0583	DNA-binding transcription factor activity
LA08_05665	COG4191	Histidine kinase
LA08_05685	COG0280	phosphate acetyltransferase
LA08_05685	COG0281	malic enzyme
LA08_05720	COG0352	thiamine-phosphate diphosphorylase activity
LA08_05725	COG1773	rubredoxin
LA08_05730	COG2912	Transglutaminase-like superfamily
LA08_05750	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LA08_05775	COG0006	proline dipeptidase activity
LA08_05810	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LA08_05830	COG1561	YicC-like family, N-terminal region
LA08_05855	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LA08_05865	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LA08_05875	COG0254	rRNA binding
LA08_05890	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LA08_05940	COG0714	Associated with various cellular activities
LA08_05960	COG2304	oxidoreductase activity
LA08_05980	COG1301	dicarboxylic acid transport
LA08_05985	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LA08_05995	COG0739	heme binding
LA08_06000	COG1376	ErfK ybiS ycfS ynhG family protein
LA08_06025	COG1022	Amp-dependent synthetase and ligase
LA08_06035	COG1028	Short-chain dehydrogenase reductase Sdr
LA08_06045	COG0745	RESPONSE REGULATOR receiver
LA08_06050	COG0642	Histidine kinase
LA08_06070	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
LA08_06075	COG4149	molybdate abc transporter
LA08_06080	COG0725	ABC transporter, periplasmic molybdate-binding protein
LA08_06085	COG3453	Protein conserved in bacteria
LA08_06085	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LA08_06120	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LA08_06140	COG2205	protein histidine kinase activity
LA08_06145	COG0745	RESPONSE REGULATOR receiver
LA08_06195	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LA08_06200	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LA08_06290	COG2201	protein-glutamate methylesterase activity
LA08_06355	COG1842	Phage shock protein A
LA08_06380	COG0754	glutathionylspermidine amidase activity
LA08_06395	COG0789	Transcriptional regulator
LA08_06450	COG0531	amino acid
LA08_06455	COG2197	response regulator
LA08_06470	COG1113	amino acid transport
LA08_06490	COG1271	oxidase subunit
LA08_06495	COG1294	oxidase, subunit
LA08_06505	COG2239	Acts as a magnesium transporter
LA08_06515	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LA08_06520	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LA08_06540	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LA08_06555	COG1137	ATPase activity
LA08_06560	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
LA08_06570	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LA08_06580	COG0271	Belongs to the BolA IbaG family
LA08_06610	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LA08_06635	COG0628	permease
LA08_06645	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LA08_06650	COG3178	'Phosphotransferase
LA08_06665	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LA08_06670	COG1555	photosystem II stabilization
LA08_06715	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LA08_06730	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LA08_06780	COG0534	Mate efflux family protein
LA08_06820	COG0542	response to heat
LA08_06860	COG4206	TonB-dependent receptor
LA08_06920	COG0019	diaminopimelate decarboxylase activity
LA08_06930	COG2814	Major facilitator Superfamily
LA08_06935	COG4264	IucA IucC family
LA08_06945	COG4772	TonB-dependent receptor
LA08_06960	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LA08_06960	COG4651	solute:proton antiporter activity
LA08_06995	COG0488	(ABC) transporter
LA08_07020	COG2755	lipolytic protein G-D-S-L family
LA08_07020	COG0657	acetylesterase activity
LA08_07040	COG2207	Transcriptional regulator
LA08_07045	COG0326	Molecular chaperone. Has ATPase activity
LA08_07075	COG3328	transposase activity
LA08_07080	COG0174	glutamine synthetase
LA08_07085	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
LA08_07095	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LA08_07150	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LA08_07155	COG0719	Fe-S assembly protein
LA08_07160	COG0396	ATPase activity
LA08_07165	COG0719	Fe-S assembly protein
LA08_07170	COG1959	2 iron, 2 sulfur cluster binding
LA08_07190	COG0693	protein deglycase activity
LA08_07235	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LA08_07270	COG0519	Catalyzes the synthesis of GMP from XMP
LA08_07300	COG1764	response to oxidative stress
LA08_07310	COG0384	phenazine biosynthesis protein PhzF
LA08_07320	COG0527	aspartate kinase activity
LA08_07350	COG0142	geranyltranstransferase activity
LA08_07355	COG0629	single-stranded DNA binding
LA08_07360	COG2203	Gaf domain
LA08_07360	COG3706	GGDEF domain
LA08_07360	COG4251	negative regulation of phosphorylation
LA08_07360	COG5001	Diguanylate cyclase
LA08_07395	COG2879	small protein
LA08_07400	COG1966	Carbon starvation protein
LA08_07405	COG1741	Belongs to the pirin family
LA08_07415	COG3501	Rhs element vgr protein
LA08_07435	COG3501	Rhs element vgr protein
LA08_07465	COG3501	Rhs element vgr protein
LA08_07520	COG1741	Belongs to the pirin family
LA08_07530	COG1515	deoxyribonuclease V activity
LA08_07550	COG3590	peptidase
LA08_07565	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LA08_07570	COG2199	diguanylate cyclase activity
LA08_07570	COG2200	EAL domain
LA08_07570	COG2202	Pas domain
LA08_07575	COG0835	chemotaxis
LA08_07580	COG0840	transmembrane signaling receptor activity
LA08_07585	COG2198	Histidine kinase
LA08_07585	COG0643	Histidine kinase
LA08_07595	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LA08_07605	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LA08_07625	COG2205	protein histidine kinase activity
LA08_07640	COG3039	Transposase
LA08_07660	COG3039	Transposase
LA08_07685	COG3039	Transposase
LA08_07705	COG3039	Transposase
LA08_07740	COG0735	belongs to the Fur family
LA08_07800	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LA08_07805	COG0084	hydrolase, TatD family'
LA08_07820	COG1960	acyl-CoA dehydrogenase activity
LA08_07835	COG0367	asparagine synthase
LA08_07845	COG0305	Participates in initiation and elongation during chromosome replication
LA08_07850	COG0415	Belongs to the DNA photolyase family
LA08_07870	COG1028	Short-chain dehydrogenase reductase Sdr
LA08_07915	COG3039	Transposase
LA08_07975	COG5002	protein histidine kinase activity
LA08_07975	COG5001	Diguanylate cyclase
LA08_07980	COG1187	pseudouridine synthase activity
LA08_08015	COG0475	glutathione-regulated potassium exporter activity
LA08_08020	COG5002	protein histidine kinase activity
LA08_08020	COG5000	phosphorelay sensor kinase activity
LA08_08025	COG0745	RESPONSE REGULATOR receiver
LA08_08055	COG1132	(ABC) transporter
LA08_08080	COG3039	Transposase
LA08_08095	COG3039	Transposase
LA08_08140	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LA08_08150	COG4969	Belongs to the N-Me-Phe pilin family
LA08_08155	COG2194	sulfuric ester hydrolase activity
LA08_08200	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LA08_08215	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LA08_08215	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LA08_08220	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LA08_08225	COG0564	pseudouridine synthase activity
LA08_08250	COG3387	PFAM Glycoside hydrolase 15-related
LA08_08255	COG1877	trehalose-phosphatase activity
LA08_08315	COG1595	DNA-templated transcription, initiation
LA08_08325	COG1946	Acyl-CoA thioesterase
LA08_08340	COG0824	Thioesterase
LA08_08345	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LA08_08365	COG0268	Binds directly to 16S ribosomal RNA
LA08_08370	COG0728	peptidoglycan biosynthetic process
LA08_08375	COG0196	riboflavin kinase activity
LA08_08405	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LA08_08410	COG1845	cytochrome c oxidase, subunit III
LA08_08415	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LA08_08425	COG3501	Rhs element vgr protein
LA08_08435	COG3209	COG3209 Rhs family protein
LA08_08435	COG3209	COG3209 Rhs family protein
LA08_08570	COG0824	Thioesterase
LA08_08580	COG0848	biopolymer transport protein
LA08_08595	COG2885	chlorophyll binding
LA08_08605	COG0602	queuosine metabolic process
LA08_08615	COG1187	pseudouridine synthase activity
LA08_08700	COG0514	ATP-dependent DNA helicase (RecQ)
LA08_08710	COG0783	Belongs to the Dps family
LA08_08715	COG1643	Atp-dependent helicase
LA08_08770	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LA08_08785	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LA08_08795	COG1199	ATP-dependent helicase activity
LA08_08805	COG1397	ADP-ribosylglycohydrolase
LA08_08815	COG0189	ligase activity
LA08_08830	COG0835	chemotaxis
LA08_08835	COG0840	transmembrane signaling receptor activity
LA08_08885	COG1446	asparaginase
LA08_08890	COG3142	Participates in the control of copper homeostasis
LA08_08945	COG3537	Alpha-1,2-mannosidase
LA08_09015	COG1472	Belongs to the glycosyl hydrolase 3 family
LA08_09035	COG1388	LysM domain
LA08_09035	COG3858	chitin binding
LA08_09050	COG0837	glucose binding
LA08_09055	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LA08_09065	COG0494	nUDIX hydrolase
LA08_09075	COG3956	TIGRFAM MazG family protein
LA08_09080	COG1742	UPF0060 membrane protein
LA08_09090	COG0330	HflC and HflK could
LA08_09140	COG1960	acyl-CoA dehydrogenase activity
LA08_09150	COG1309	transcriptional regulator
LA08_09155	COG4771	TonB-dependent receptor
LA08_09165	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LA08_09175	COG0463	Glycosyl transferase, family 2
LA08_09195	COG1272	protein, Hemolysin III
LA08_09205	COG0739	heme binding
LA08_09210	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LA08_09215	COG0626	cystathionine gamma-synthase activity
LA08_09225	COG1760	l-serine dehydratase
LA08_09240	COG2353	YceI-like domain
LA08_09250	COG2353	YceI-like domain
LA08_09300	COG3867	Arabinogalactan endo-beta-1,4-galactanase
LA08_09320	COG1960	acyl-CoA dehydrogenase activity
LA08_09325	COG1024	Enoyl-CoA hydratase
LA08_09345	COG1250	3-hydroxyacyl-CoA dehydrogenase
LA08_09345	COG1024	Enoyl-CoA hydratase
LA08_09360	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LA08_09420	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LA08_09425	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
LA08_09430	COG3046	protein related to deoxyribodipyrimidine photolyase
LA08_09445	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LA08_09450	COG1278	Cold shock
LA08_09470	COG1201	RNA secondary structure unwinding
LA08_09475	COG1793	dna ligase
LA08_09485	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
LA08_09485	COG1793	dna ligase
LA08_09500	COG0745	RESPONSE REGULATOR receiver
LA08_09500	COG3706	GGDEF domain
LA08_09515	COG0183	Belongs to the thiolase family
LA08_09540	COG1451	nucleotide metabolic process
LA08_09555	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LA08_09600	COG1047	Peptidyl-prolyl cis-trans
LA08_09615	COG2824	Alkylphosphonate utilization operon protein PhnA
LA08_09630	COG1902	pentaerythritol trinitrate reductase activity
LA08_09635	COG2814	Major facilitator Superfamily
LA08_09690	COG0392	lysyltransferase activity
LA08_09690	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LA08_09700	COG0251	oxidation-reduction process
LA08_09705	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LA08_09720	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LA08_09745	COG1595	DNA-templated transcription, initiation
LA08_09765	COG2878	Part of a membrane complex involved in electron transport
LA08_09795	COG0833	amino acid
LA08_09800	COG2040	homocysteine
LA08_09815	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LA08_09850	COG2895	sulfate adenylyltransferase (ATP) activity
LA08_09850	COG0529	Catalyzes the synthesis of activated sulfate
LA08_09920	COG1131	(ABC) transporter
LA08_09925	COG4771	TonB-dependent receptor
LA08_09980	COG0750	zinc metalloprotease
LA08_09990	COG0575	Belongs to the CDS family
LA08_10055	COG0024	Methionine aminopeptidase
LA08_10075	COG1393	Belongs to the ArsC family
LA08_10090	COG0367	asparagine synthase
LA08_10105	COG4774	siderophore transport
LA08_10145	COG1566	PFAM secretion protein HlyD family protein
LA08_10150	COG2814	Major facilitator Superfamily
LA08_10205	COG1960	acyl-CoA dehydrogenase activity
LA08_10230	COG2914	Belongs to the UPF0125 (RnfH) family
LA08_10240	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LA08_10250	COG0497	DNA recombination
LA08_10280	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
LA08_10285	COG1605	Chorismate mutase
LA08_10285	COG0287	Prephenate dehydrogenase
LA08_10305	COG0583	DNA-binding transcription factor activity
LA08_10320	COG1132	(ABC) transporter
LA08_10355	COG2850	peptidyl-arginine hydroxylation
LA08_10435	COG1131	(ABC) transporter
LA08_10440	COG1725	Transcriptional regulator
LA08_10450	COG0386	Belongs to the glutathione peroxidase family
LA08_10490	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LA08_10500	COG0646	methionine synthase
LA08_10500	COG1410	methionine synthase
LA08_10505	COG0646	methionine synthase
LA08_10505	COG1410	methionine synthase
LA08_10515	COG1960	acyl-CoA dehydrogenase activity
LA08_10545	COG0557	exoribonuclease II activity
LA08_10565	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LA08_10580	COG3039	Transposase
LA08_10605	COG3328	transposase activity
LA08_10615	COG1278	Cold shock
LA08_10630	COG3039	Transposase
LA08_10635	COG3039	Transposase
LA08_10685	COG3039	Transposase
LA08_10695	COG0583	DNA-binding transcription factor activity
LA08_10755	COG2201	protein-glutamate methylesterase activity
LA08_10800	COG0531	amino acid
LA08_10805	COG0531	amino acid
LA08_10815	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LA08_10820	COG0277	FAD linked oxidase domain protein
LA08_10885	COG0436	Aminotransferase
LA08_10910	COG1187	pseudouridine synthase activity
LA08_10915	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LA08_10920	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LA08_10925	COG2350	Protein conserved in bacteria
LA08_10955	COG1175	transmembrane transport
LA08_10960	COG0395	ABC-type sugar transport system, permease component
LA08_10985	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LA08_10995	COG2957	Belongs to the agmatine deiminase family
LA08_11005	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LA08_11015	COG0539	negative regulation of cytoplasmic translation
LA08_11030	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
LA08_11035	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LA08_11045	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LA08_11085	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LA08_11090	COG0583	DNA-binding transcription factor activity
LA08_11120	COG0583	DNA-binding transcription factor activity
LA08_11135	COG2201	protein-glutamate methylesterase activity
LA08_11145	COG1914	H( )-stimulated, divalent metal cation uptake system
LA08_11150	COG1321	iron dependent repressor
LA08_11155	COG0590	tRNA wobble adenosine to inosine editing
LA08_11165	COG0668	transmembrane transport
LA08_11205	COG3039	Transposase
LA08_11225	COG1028	Short-chain dehydrogenase reductase Sdr
LA08_11230	COG1183	phosphatidylcholine synthase activity
LA08_11240	COG3243	poly(R)-hydroxyalkanoic acid synthase
LA08_11255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LA08_11255	COG0723	plastoquinol--plastocyanin reductase activity
LA08_11265	COG2183	response to ionizing radiation
LA08_11280	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
LA08_11295	COG0671	phosphoesterase, PA-phosphatase related
LA08_11320	COG1794	racemase activity, acting on amino acids and derivatives
LA08_11330	COG0697	spore germination
LA08_11355	COG1012	belongs to the aldehyde dehydrogenase family
LA08_11390	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LA08_11405	COG0124	histidyl-tRNA synthetase
LA08_11460	COG0140	phosphoribosyl-ATP diphosphatase activity
LA08_11460	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LA08_11500	COG0653	protein targeting
LA08_11655	COG2201	protein-glutamate methylesterase activity
LA08_11665	COG2801	Transposase and inactivated derivatives
LA08_11680	COG3039	Transposase
LA08_11705	COG3328	transposase activity
LA08_11750	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LA08_11770	COG0848	biopolymer transport protein
LA08_11775	COG0811	peptide transport
LA08_11805	COG4591	ABC-type transport system involved in lipoprotein release permease component
LA08_11820	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LA08_11835	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LA08_11850	COG0354	folic acid binding
LA08_11865	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LA08_11875	COG0363	glucosamine-6-phosphate deaminase activity
LA08_11880	COG0129	dihydroxy-acid dehydratase activity
LA08_11885	COG0800	Aldolase
LA08_11915	COG5002	protein histidine kinase activity
LA08_11915	COG0784	Response regulator, receiver
LA08_11915	COG2205	protein histidine kinase activity
LA08_11945	COG3706	GGDEF domain
LA08_12000	COG0386	Belongs to the glutathione peroxidase family
LA08_12090	COG2203	Gaf domain
LA08_12090	COG3706	GGDEF domain
LA08_12090	COG4251	negative regulation of phosphorylation
LA08_12090	COG5001	Diguanylate cyclase
LA08_12110	COG1472	Belongs to the glycosyl hydrolase 3 family
LA08_12160	COG0617	tRNA 3'-terminal CCA addition
LA08_12175	COG0860	N-Acetylmuramoyl-L-alanine amidase
LA08_12225	COG4566	intracellular signal transduction
LA08_12270	COG0077	Prephenate dehydratase
LA08_12270	COG1605	Chorismate mutase
LA08_12280	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LA08_12330	COG2986	histidine ammonia-lyase
LA08_12340	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LA08_12380	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
LA08_12395	COG3115	cell septum assembly
LA08_12420	COG0316	Belongs to the HesB IscA family
LA08_12455	COG0288	reversible hydration of carbon dioxide
LA08_12480	COG2925	Exonuclease
LA08_12490	COG0667	Aldo Keto reductase
LA08_12560	COG0494	nUDIX hydrolase
LA08_12570	COG1024	Enoyl-CoA hydratase
LA08_12580	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LA08_12595	COG3039	Transposase
LA08_12635	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LA08_12640	COG0573	inorganic phosphate transmembrane transporter activity
LA08_12655	COG0704	Plays a role in the regulation of phosphate uptake
LA08_12665	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LA08_12680	COG3328	transposase activity
LA08_12715	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LA08_12725	COG1862	Preprotein translocase
LA08_12815	COG0405	Gamma-glutamyltransferase
LA08_12820	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LA08_12840	COG0742	ribosomal rna small subunit methyltransferase
LA08_12860	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LA08_12890	COG3039	Transposase
LA08_12900	COG3039	Transposase
LA08_12930	COG0303	'Molybdopterin
LA08_12940	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LA08_12950	COG1426	Protein conserved in bacteria
LA08_12965	COG0105	UTP biosynthetic process
LA08_12975	COG1250	3-hydroxyacyl-CoA dehydrogenase
LA08_12975	COG1024	Enoyl-CoA hydratase
LA08_12980	COG0183	Belongs to the thiolase family
LA08_12985	COG0038	chloride channel
LA08_13005	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LA08_13030	COG1674	ftsk spoiiie
LA08_13035	COG0492	ferredoxin-NADP+ reductase activity
LA08_13055	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LA08_13060	COG0542	response to heat
LA08_13065	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LA08_13075	COG0482	sulfurtransferase activity
LA08_13100	COG5001	Diguanylate cyclase
LA08_13105	COG4585	Histidine kinase
LA08_13115	COG5002	protein histidine kinase activity
LA08_13135	COG0835	chemotaxis
LA08_13135	COG0784	Response regulator, receiver
LA08_13145	COG1558	bacterial-type flagellum-dependent cell motility
LA08_13150	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
LA08_13155	COG1749	Flagellar hook protein flgE
LA08_13160	COG4787	bacterial-type flagellum-dependent cell motility
LA08_13170	COG4786	Flagellar basal body rod
LA08_13200	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LA08_13205	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LA08_13235	COG2201	protein-glutamate methylesterase activity
LA08_13240	COG2204	response regulator
LA08_13255	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LA08_13265	COG1028	Short-chain dehydrogenase reductase Sdr
LA08_13300	COG1677	Flagellar hook-basal body complex protein FliE
LA08_13350	COG3190	flagellar
LA08_13365	COG1987	bacterial-type flagellum assembly
LA08_13370	COG1684	flagellar biosynthetic protein fliR
LA08_13375	COG5001	Diguanylate cyclase
LA08_13375	COG3300	MHYT domain
LA08_13380	COG5001	Diguanylate cyclase
LA08_13380	COG3300	MHYT domain
LA08_13395	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LA08_13405	COG0455	bacterial-type flagellum organization
LA08_13425	COG2198	Histidine kinase
LA08_13425	COG0643	Histidine kinase
LA08_13465	COG3039	Transposase
LA08_13555	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LA08_13560	COG4988	ABC transporter
LA08_13585	COG1271	oxidase subunit
LA08_13655	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LA08_13660	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LA08_13670	COG0137	argininosuccinate synthase activity
LA08_13675	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LA08_13690	COG2166	iron-sulfur cluster assembly
LA08_13705	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LA08_13715	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LA08_13755	COG3039	Transposase
LA08_13770	COG4677	pectinesterase activity
LA08_13805	COG0402	S-adenosylhomocysteine deaminase activity
LA08_13820	COG1509	lysine 2,3-aminomutase activity
LA08_13825	COG5001	Diguanylate cyclase
LA08_13825	COG3300	MHYT domain
LA08_13840	COG0483	inositol monophosphate 1-phosphatase activity
LA08_13875	COG0513	Belongs to the DEAD box helicase family
LA08_13895	COG0625	glutathione transferase activity
LA08_13910	COG4681	YaeQ
LA08_13915	COG2081	HI0933 family
LA08_13935	COG1028	Short-chain dehydrogenase reductase Sdr
LA08_13965	COG0860	N-Acetylmuramoyl-L-alanine amidase
LA08_13970	COG0802	atpase or kinase
LA08_13975	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LA08_13975	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LA08_13980	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LA08_14005	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LA08_14090	COG3328	transposase activity
LA08_14135	COG2969	positive regulation of protein catabolic process
LA08_14140	COG0625	glutathione transferase activity
LA08_14145	COG2857	Cytochrome c1
LA08_14150	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LA08_14155	COG0723	plastoquinol--plastocyanin reductase activity
LA08_14165	COG0741	lytic transglycosylase activity
LA08_14190	COG1702	phosphate starvation-inducible protein PhoH
LA08_14210	COG4535	Mg2 and Co2 transporter CorC
LA08_14225	COG1012	belongs to the aldehyde dehydrogenase family
LA08_14235	COG1177	transmembrane transport
LA08_14240	COG1176	ABC-type spermidine putrescine transport system, permease component I
LA08_14245	COG3842	ATPase activity
LA08_14285	COG0174	glutamine synthetase
LA08_14290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LA08_14295	COG0745	RESPONSE REGULATOR receiver
LA08_14295	COG3706	GGDEF domain
LA08_14300	COG0477	Major facilitator Superfamily
LA08_14310	COG0243	molybdopterin cofactor binding
LA08_14345	COG1121	(ABC) transporter
LA08_14355	COG2733	membrane
LA08_14360	COG0784	Response regulator, receiver
LA08_14360	COG2205	protein histidine kinase activity
LA08_14360	COG5002	protein histidine kinase activity
LA08_14370	COG3039	Transposase
LA08_14380	COG2902	Dehydrogenase
LA08_14390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LA08_14395	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LA08_14415	COG1609	Transcriptional regulator
LA08_14420	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LA08_14420	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LA08_14425	COG1105	Belongs to the carbohydrate kinase PfkB family
LA08_14430	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LA08_14430	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LA08_14445	COG3039	Transposase
LA08_14455	COG3039	Transposase
LA08_14500	COG3501	Rhs element vgr protein
LA08_14520	COG3501	Rhs element vgr protein
LA08_14580	COG3039	Transposase
LA08_14610	COG4771	TonB-dependent receptor
LA08_14620	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LA08_14640	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LA08_14645	COG1360	Flagellar Motor Protein
LA08_14650	COG1192	Involved in chromosome partitioning
LA08_14655	COG0835	chemotaxis
LA08_14665	COG0745	RESPONSE REGULATOR receiver
LA08_14690	COG0840	transmembrane signaling receptor activity
LA08_14705	COG0840	transmembrane signaling receptor activity
LA08_14715	COG0840	transmembrane signaling receptor activity
LA08_14725	COG0840	transmembrane signaling receptor activity
LA08_14730	COG0840	transmembrane signaling receptor activity
LA08_14735	COG0840	transmembrane signaling receptor activity
LA08_14740	COG0840	transmembrane signaling receptor activity
LA08_14760	COG0835	chemotaxis
LA08_14785	COG0840	transmembrane signaling receptor activity
LA08_14820	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LA08_14850	COG0318	PFAM AMP-dependent synthetase and ligase
LA08_14855	COG1024	Enoyl-CoA hydratase
LA08_14860	COG2205	protein histidine kinase activity
LA08_14860	COG0784	Response regulator, receiver
LA08_14860	COG2198	Histidine kinase
LA08_14930	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LA08_14940	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LA08_14945	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LA08_14955	COG0505	Belongs to the CarA family
LA08_14960	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LA08_14970	COG2258	MOSC domain
LA08_14975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LA08_15045	COG0477	Major facilitator Superfamily
LA08_15055	COG1070	Carbohydrate kinase
LA08_15065	COG1501	Belongs to the glycosyl hydrolase 31 family
LA08_15080	COG0800	Aldolase
LA08_15095	COG3734	2-keto-3-deoxy-galactonokinase
LA08_15100	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LA08_15110	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LA08_15125	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LA08_15130	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LA08_15140	COG0351	phosphomethylpyrimidine kinase
LA08_15170	COG0583	DNA-binding transcription factor activity
LA08_15175	COG1741	Belongs to the pirin family
LA08_15195	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LA08_15200	COG0305	Participates in initiation and elongation during chromosome replication
LA08_15225	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LA08_15235	COG2137	regulation of response to DNA damage stimulus
LA08_15260	COG1546	Belongs to the CinA family
LA08_15265	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LA08_15270	COG1923	regulation of RNA biosynthetic process
LA08_15280	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LA08_15285	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LA08_15295	COG1534	Rna-binding protein
LA08_15310	COG1238	metal cluster binding
LA08_15325	COG2840	Smr protein MutS2
LA08_15400	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LA08_15405	COG0306	phosphate transporter
LA08_15420	COG1253	flavin adenine dinucleotide binding
LA08_15435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LA08_15455	COG0477	Major facilitator Superfamily
LA08_15465	COG1132	(ABC) transporter
LA08_15470	COG1136	(ABC) transporter
LA08_15490	COG0438	transferase activity, transferring glycosyl groups
LA08_15500	COG2264	protein methyltransferase activity
LA08_15530	COG2244	polysaccharide biosynthetic process
LA08_15580	COG1595	DNA-templated transcription, initiation
LA08_15595	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LA08_15615	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LA08_15630	COG2201	protein-glutamate methylesterase activity
LA08_15650	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LA08_15655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LA08_15710	COG1858	cytochrome C peroxidase
LA08_15745	COG0515	serine threonine protein kinase
LA08_15750	COG0631	protein serine/threonine phosphatase activity
LA08_15785	COG3501	Rhs element vgr protein
LA08_15860	COG3039	Transposase
LA08_15880	COG3039	Transposase
LA08_15925	COG0316	Belongs to the HesB IscA family
LA08_15925	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
LA08_15930	COG2154	pterin-4-alpha-carbinolamine dehydratase
LA08_15940	COG0428	transporter
LA08_15945	COG0428	transporter
LA08_15950	COG3064	Membrane
LA08_15960	COG1530	ribonuclease E activity
LA08_15985	COG3039	Transposase
LA08_16005	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LA08_16045	COG3039	Transposase
LA08_16050	COG3039	Transposase
LA08_16080	COG1648	precorrin-2 dehydrogenase activity
LA08_16080	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LA08_16105	COG0746	molybdenum cofactor guanylyltransferase activity
LA08_16180	COG3328	transposase activity
LA08_16185	COG4206	TonB-dependent receptor
LA08_16220	COG4206	TonB-dependent receptor
LA08_16270	COG0531	amino acid
LA08_16285	COG0006	proline dipeptidase activity
LA08_16295	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LA08_16310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LA08_16315	COG3938	Belongs to the proline racemase family
LA08_16325	COG0552	protein localization to endoplasmic reticulum
LA08_16350	COG4191	Histidine kinase
LA08_16350	COG0784	Response regulator, receiver
LA08_16440	COG3040	lipid binding
LA08_16490	COG0438	transferase activity, transferring glycosyl groups
LA08_16495	COG0438	transferase activity, transferring glycosyl groups
LA08_16540	COG0776	regulation of translation
LA08_16555	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LA08_16560	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LA08_16565	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LA08_16600	COG0556	nucleotide-excision repair
LA08_16605	COG4969	Belongs to the N-Me-Phe pilin family
LA08_16645	COG1611	Belongs to the LOG family
LA08_16660	COG2095	MarC family integral membrane protein
LA08_16670	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LA08_16675	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LA08_16710	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LA08_16730	COG0195	Participates in both transcription termination and antitermination
LA08_16745	COG1007	ATP synthesis coupled electron transport
LA08_16760	COG0713	ATP synthesis coupled electron transport
LA08_16780	COG1034	ATP synthesis coupled electron transport
LA08_16785	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LA08_16790	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
LA08_16810	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LA08_16830	COG1028	Short-chain dehydrogenase reductase Sdr
LA08_16930	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LA08_16935	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LA08_16945	COG2890	protein-(glutamine-N5) methyltransferase activity
LA08_17000	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LA08_17010	COG0412	Dienelactone hydrolase
LA08_17040	COG0489	protein tyrosine kinase activity
LA08_17085	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LA08_17090	COG2311	Membrane
LA08_17095	COG1047	Peptidyl-prolyl cis-trans
LA08_17100	COG0791	NLP P60 protein
LA08_17105	COG0791	NLP P60 protein
LA08_17120	COG1301	dicarboxylic acid transport
LA08_17125	COG1785	Belongs to the alkaline phosphatase family
LA08_17130	COG0037	tRNA processing
LA08_17140	COG0142	geranyltranstransferase activity
LA08_17165	COG0312	modulator of DNA gyrase
LA08_17170	COG3028	Belongs to the UPF0307 family
LA08_17175	COG0312	modulator of DNA gyrase
LA08_17185	COG3164	Protein of unknown function
LA08_17190	COG1530	ribonuclease E activity
LA08_17200	COG2968	Membrane
LA08_17250	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LA08_17280	COG3118	belongs to the thioredoxin family
LA08_17360	COG3039	Transposase
LA08_17365	COG3039	Transposase
LA08_17475	COG3273	potassium ion transport
LA08_17475	COG0471	metal ion transport
LA08_17505	COG1970	mechanosensitive ion channel activity
LA08_17530	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LA08_17560	COG0308	aminopeptidase N
LA08_17565	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LA08_17580	COG0529	Catalyzes the synthesis of activated sulfate
LA08_17580	COG2895	sulfate adenylyltransferase (ATP) activity
LA08_17590	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LA08_17620	COG0784	Response regulator, receiver
LA08_17620	COG2198	Histidine kinase
LA08_17620	COG2205	protein histidine kinase activity
LA08_17665	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
LA08_17670	COG3588	fructose-bisphosphate aldolase
LA08_17675	COG0469	pyruvate kinase activity
LA08_17720	COG0753	catalase activity
LA08_17745	COG3039	Transposase
LA08_17765	COG2207	Transcriptional regulator
LA08_17765	COG1917	Cupin 2, conserved barrel domain protein
LA08_17795	COG0823	Involved in the tonB-independent uptake of proteins
LA08_17795	COG1506	peptidase
LA08_17820	COG3039	Transposase
LA08_17825	COG1297	OPT oligopeptide transporter protein
LA08_17895	COG0328	RNA-DNA hybrid ribonuclease activity
LA08_17895	COG0406	alpha-ribazole phosphatase activity
LA08_17930	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LA08_17935	COG3039	Transposase
LA08_17950	COG0732	type I restriction modification DNA specificity domain
LA08_17955	COG3039	Transposase
LA08_17965	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
LA08_17970	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LA08_17990	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
LA08_18110	COG3501	Rhs element vgr protein
LA08_18175	COG3501	Rhs element vgr protein
LA08_18185	COG3501	Rhs element vgr protein
LA08_18195	COG3039	Transposase
LA08_18250	COG3501	Rhs element vgr protein
LA08_18330	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LA08_18345	COG2197	response regulator
LA08_18350	COG4585	Histidine kinase
LA08_18370	COG2894	cell division
LA08_18375	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
LA08_18385	COG0642	Histidine kinase
LA08_18390	COG0745	RESPONSE REGULATOR receiver
LA08_18395	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LA08_18405	COG2194	sulfuric ester hydrolase activity
LA08_18435	COG3551	Protein conserved in bacteria
LA08_18500	COG0203	ribosomal protein L17
LA08_18505	COG0202	RNA polymerase activity
LA08_18520	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LA08_18525	COG0201	protein transport
LA08_18535	COG1841	ribosomal large subunit assembly
LA08_18540	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LA08_18560	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LA08_18580	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LA08_18585	COG0255	Belongs to the universal ribosomal protein uL29 family
LA08_18590	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LA08_18615	COG0089	rRNA binding
LA08_18655	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LA08_18695	COG0250	Participates in transcription elongation, termination and antitermination
LA08_18700	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LA08_18730	COG0012	GTP binding
LA08_18745	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LA08_18785	COG0521	Mo-molybdopterin cofactor biosynthetic process
LA08_18805	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LA08_18840	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LA08_18850	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LA08_18880	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
LA08_18885	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
LA08_18905	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
LA08_18920	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LA08_18920	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LA08_18970	COG2890	protein-(glutamine-N5) methyltransferase activity
LA08_18980	COG3634	alkyl hydroperoxide reductase activity
LA08_18985	COG0583	DNA-binding transcription factor activity
LA08_18995	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LA08_19075	COG4783	chaperone-mediated protein folding
LA08_19090	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LA08_19100	COG0438	transferase activity, transferring glycosyl groups
LA08_19105	COG0671	phosphoesterase, PA-phosphatase related
LA08_19130	COG2833	Protein of unknown function (DUF455)
LA08_19150	COG0285	dihydrofolate synthase activity
LA08_19160	COG0406	alpha-ribazole phosphatase activity
LA08_19195	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
LA08_19200	COG4208	sulfate ABC transporter
LA08_19205	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LA08_19210	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LA08_19215	COG0156	8-amino-7-oxononanoate synthase activity
LA08_19250	COG1902	pentaerythritol trinitrate reductase activity
LA08_19250	COG0446	pyridine nucleotide-disulphide oxidoreductase
LA08_19300	COG0745	RESPONSE REGULATOR receiver
LA08_19300	COG3706	GGDEF domain
LA08_19385	COG3386	PFAM SMP-30 Gluconolaconase
LA08_19405	COG1024	Enoyl-CoA hydratase
LA08_19415	COG0318	PFAM AMP-dependent synthetase and ligase
LA08_19420	COG0583	DNA-binding transcription factor activity
LA08_19460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LA08_19465	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LA08_19475	COG2096	Adenosyltransferase
LA08_19480	COG0123	including yeast histone deacetylase and acetoin utilization protein
LA08_19495	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LA08_19555	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LA08_19580	COG0642	Histidine kinase
LA08_19595	COG4181	ATPase activity
LA08_19605	COG2175	clavaminate synthase activity
LA08_19615	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
LA08_19655	COG0667	Aldo Keto reductase
LA08_19665	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LA08_19670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LA08_19690	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LA08_19705	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LA08_19765	COG2226	methyltransferase
LA08_19820	COG1028	Short-chain dehydrogenase reductase Sdr
LA08_19820	COG0604	alcohol dehydrogenase
LA08_19820	COG3321	synthase
LA08_19835	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LA08_19850	COG0494	nUDIX hydrolase
LA08_19865	COG1388	LysM domain
LA08_19865	COG4942	peptidase
LA08_19890	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LA08_19895	COG1181	Belongs to the D-alanine--D-alanine ligase family
LA08_19915	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LA08_19920	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LA08_19935	COG3116	cell division
LA08_19980	COG1988	membrane-bound metal-dependent
LA08_19985	COG0277	FAD linked oxidase domain protein
LA08_19990	COG0745	RESPONSE REGULATOR receiver
LA08_19995	COG2205	protein histidine kinase activity
LA08_20005	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LA08_20010	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
LA08_20035	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LA08_20065	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LA08_20065	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LA08_20105	COG0488	(ABC) transporter
LA08_20150	COG0745	RESPONSE REGULATOR receiver
LA08_20155	COG2205	protein histidine kinase activity
LA08_20195	COG2205	protein histidine kinase activity
LA08_20250	COG3039	Transposase
LA08_20255	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LA08_20270	COG3039	Transposase
LA08_20325	COG3039	Transposase
LA08_20375	COG0726	polysaccharide deacetylase
LA08_20375	COG1649	PFAM Uncharacterised BCR, COG1649
LA08_20380	COG1215	transferase activity, transferring glycosyl groups
LA08_20390	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LA08_20395	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LA08_20400	COG1609	Transcriptional regulator
LA08_20425	COG3250	beta-galactosidase activity
LA08_20480	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LA08_20485	COG4191	Histidine kinase
LA08_20490	COG0784	Response regulator, receiver
LA08_20495	COG4251	negative regulation of phosphorylation
LA08_20500	COG2823	Periplasmic or secreted lipoprotein
LA08_20505	COG0673	inositol 2-dehydrogenase activity
LA08_20510	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LA08_20545	COG1051	belongs to the nudix hydrolase family
LA08_20545	COG1056	cytidyltransferase-related domain
LA08_20595	COG1686	Belongs to the peptidase S11 family
LA08_20605	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LA08_20610	COG2951	lytic endotransglycosylase activity
LA08_20625	COG1388	LysM domain
LA08_20625	COG3409	Peptidoglycan-binding domain 1 protein
LA08_20625	COG5632	N-Acetylmuramoyl-L-alanine amidase
LA08_20670	COG0772	Belongs to the SEDS family
LA08_20685	COG1792	Involved in formation and maintenance of cell shape
LA08_20690	COG1077	Cell shape determining protein MreB Mrl
LA08_20740	COG2199	diguanylate cyclase activity
LA08_20745	COG0308	aminopeptidase N
LA08_20775	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LA08_20820	COG1505	serine-type exopeptidase activity
LA08_20855	COG3275	phosphorelay sensor kinase activity
LA08_20900	COG0659	secondary active sulfate transmembrane transporter activity
LA08_20905	COG5297	Belongs to the glycosyl hydrolase family 6
LA08_20905	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LA08_20980	COG0598	Magnesium transport protein CorA
LA08_20990	COG1113	amino acid transport
LA08_21000	COG5297	Belongs to the glycosyl hydrolase family 6
LA08_21005	COG4305	rare lipoprotein A
LA08_21010	COG0697	spore germination
LA08_21070	COG4221	oxidoreductase activity
LA08_21100	COG0456	acetyltransferase
LA08_21110	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
LA08_21165	COG2111	Na H antiporter
LA08_21165	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LA08_21170	COG1006	Multisubunit Na H antiporter MnhC subunit
LA08_21175	COG0651	ATP synthesis coupled electron transport
LA08_21185	COG2212	antiporter activity
LA08_21190	COG1320	monovalent cation:proton antiporter activity
LA08_21220	COG3104	oligopeptide transport
LA08_21235	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LA08_21270	COG0183	Belongs to the thiolase family
LA08_21325	COG3039	Transposase
LA08_21355	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
LA08_21360	COG3023	N-Acetylmuramoyl-L-alanine amidase
LA08_21370	COG4948	Mandelate Racemase Muconate Lactonizing
LA08_21410	COG0531	amino acid
LA08_21445	COG4682	membrane
LA08_21450	COG2133	pyrroloquinoline quinone binding
LA08_21490	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LA08_21500	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LA08_21505	COG1610	YqeY-like protein
LA08_21520	COG1295	ribonuclease BN
LA08_21525	COG0358	DNA primase activity
LA08_21590	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
LA08_21605	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LA08_21775	COG3039	Transposase
LA08_21790	COG3328	transposase activity
LA08_21815	COG1473	amidohydrolase
LA08_21820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LA08_21825	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LA08_21840	COG5383	Protein conserved in bacteria
LA08_21880	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LA08_21900	COG0028	Belongs to the TPP enzyme family
LA08_21905	COG4191	Histidine kinase
LA08_21930	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LA08_21945	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LA08_21950	COG3177	Filamentation induced by cAMP protein fic
LA08_21965	COG0596	Alpha beta hydrolase
LA08_21975	COG0318	PFAM AMP-dependent synthetase and ligase
LA08_21980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LA08_22035	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LA08_22070	COG3039	Transposase
LA08_22180	COG2353	YceI-like domain
LA08_22210	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LA08_22225	COG3386	PFAM SMP-30 Gluconolaconase
LA08_22265	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LA08_22280	COG4771	TonB-dependent receptor
LA08_22295	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LA08_22315	COG1252	NADH dehydrogenase
LA08_22325	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LA08_22335	COG3437	response regulator, receiver
LA08_22340	COG2177	Part of the ABC transporter FtsEX involved in
LA08_22345	COG2884	Cell division ATP-binding protein ftsE
LA08_22355	COG3118	belongs to the thioredoxin family
LA08_22360	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LA08_22375	COG0729	surface antigen
LA08_22380	COG2911	Protein conserved in bacteria
LA08_22415	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LA08_22430	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LA08_22490	COG1733	regulation of RNA biosynthetic process
LA08_22495	COG0702	epimerase
LA08_22530	COG0583	DNA-binding transcription factor activity
LA08_22535	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LA08_22555	COG0745	RESPONSE REGULATOR receiver
LA08_22585	COG1902	pentaerythritol trinitrate reductase activity
LA08_22590	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LA08_22600	COG2814	Major facilitator Superfamily
LA08_22605	COG0583	DNA-binding transcription factor activity
LA08_22625	COG0084	hydrolase, TatD family'
LA08_22675	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LA08_22750	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LA08_22755	COG1960	acyl-CoA dehydrogenase activity
LA08_22810	COG0523	cobalamin synthesis protein
LA08_22820	COG0697	spore germination
LA08_22830	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LA08_22845	COG4771	TonB-dependent receptor
LA08_22850	COG0457	Tetratricopeptide repeat
LA08_22865	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LA08_22890	COG0519	Catalyzes the synthesis of GMP from XMP
LA08_22890	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LA08_22900	COG0805	protein transport
LA08_22910	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LA08_22920	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LA08_22975	COG3661	Belongs to the glycosyl hydrolase 67 family
LA08_22985	COG4948	Mandelate Racemase Muconate Lactonizing
LA08_22995	COG1472	Belongs to the glycosyl hydrolase 3 family
LA08_23000	COG0246	Mannitol dehydrogenase
LA08_23025	COG3693	PFAM glycoside hydrolase, family 10
LA08_23050	COG2211	Major facilitator Superfamily
LA08_23095	COG4943	cyclic-guanylate-specific phosphodiesterase activity
LA08_23145	COG1846	Transcriptional regulator
LA08_23150	COG1764	response to oxidative stress
LA08_23250	COG3549	Plasmid maintenance system killer
LA08_23260	COG1074	ATP-dependent DNA helicase activity
LA08_23265	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LA08_23305	COG2032	superoxide dismutase activity
LA08_23310	COG2032	superoxide dismutase activity
LA08_23315	COG2204	response regulator
LA08_23320	COG3852	Histidine kinase
LA08_23325	COG0004	ammonium transporteR
LA08_23330	COG0347	Belongs to the P(II) protein family
LA08_23335	COG0174	glutamine synthetase
LA08_23385	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LA08_23395	COG2062	phosphohistidine phosphatase, SixA
LA08_23400	COG0489	protein tyrosine kinase activity
LA08_23420	COG1396	sequence-specific DNA binding
LA08_23425	COG3550	peptidyl-serine autophosphorylation
LA08_23430	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
LA08_23435	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LA08_23450	COG1125	glycine betaine transport
LA08_23450	COG0517	IMP dehydrogenase activity
LA08_23465	COG1119	ATPase activity
LA08_23475	COG1752	Esterase of the alpha-beta hydrolase superfamily
LA08_23490	COG3039	Transposase
LA08_23515	COG0656	L-ascorbic acid biosynthetic process
LA08_23520	COG2130	NADP-dependent
LA08_23525	COG0667	Aldo Keto reductase
LA08_23535	COG1187	pseudouridine synthase activity
LA08_23550	COG1643	Atp-dependent helicase
LA08_23555	COG4807	Protein conserved in bacteria
LA08_23560	COG4948	Mandelate Racemase Muconate Lactonizing
LA08_23570	COG0179	Fumarylacetoacetate (FAA) hydrolase
LA08_23575	COG1028	Short-chain dehydrogenase reductase Sdr
LA08_23595	COG3507	Belongs to the glycosyl hydrolase 43 family
LA08_23640	COG3162	membrane
LA08_23645	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LA08_23660	COG0708	Exodeoxyribonuclease III
LA08_23675	COG2091	lysine biosynthetic process via aminoadipic acid
LA08_23685	COG3540	Alkaline phosphatase
LA08_23705	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LA08_23710	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LA08_23715	COG2159	amidohydrolase
LA08_23740	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LA08_23745	COG0583	DNA-binding transcription factor activity
LA08_23750	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LA08_23770	COG0210	DNA helicase
LA08_23785	COG0531	amino acid
LA08_23795	COG1322	Protein conserved in bacteria
LA08_23805	COG0386	Belongs to the glutathione peroxidase family
LA08_23860	COG0793	Belongs to the peptidase S41A family
LA08_23865	COG4942	peptidase
LA08_23875	COG2234	aminopeptidase activity
LA08_23925	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LA08_23930	COG0302	gtp cyclohydrolase
LA08_23955	COG0477	Major facilitator Superfamily
LA08_24055	COG1929	Belongs to the glycerate kinase type-1 family
LA08_24060	COG2271	Major facilitator Superfamily
LA08_24075	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LA08_24085	COG0861	Integral membrane protein TerC family
LA08_24095	COG0584	glycerophosphoryl diester phosphodiesterase
LA08_24105	COG0671	phosphoesterase, PA-phosphatase related
LA08_24115	COG0726	polysaccharide deacetylase
LA08_24130	COG0230	Belongs to the bacterial ribosomal protein bL34 family