locus-tag	class	description
EBA16_00025	COG0187	DNA topoisomerase II activity
EBA16_00035	COG0501	Belongs to the peptidase M48B family
EBA16_00065	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EBA16_00095	COG3039	Transposase
EBA16_00145	COG0793	Belongs to the peptidase S41A family
EBA16_00150	COG4942	peptidase
EBA16_00160	COG2234	aminopeptidase activity
EBA16_00170	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA16_00185	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA16_00195	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA16_00205	COG1064	alcohol dehydrogenase
EBA16_00230	COG0493	'glutamate synthase
EBA16_00235	COG0070	glutamate synthase
EBA16_00235	COG0069	glutamate synthase activity
EBA16_00235	COG0067	glutamate synthase
EBA16_00305	COG1205	dead DEAH box helicase
EBA16_00305	COG1111	helicase
EBA16_00310	COG1272	protein, Hemolysin III
EBA16_00340	COG2032	superoxide dismutase activity
EBA16_00345	COG2204	response regulator
EBA16_00350	COG3852	Histidine kinase
EBA16_00355	COG0004	ammonium transporteR
EBA16_00360	COG0347	Belongs to the P(II) protein family
EBA16_00365	COG0174	glutamine synthetase
EBA16_00420	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EBA16_00430	COG2062	phosphohistidine phosphatase, SixA
EBA16_00435	COG0489	protein tyrosine kinase activity
EBA16_00455	COG1396	sequence-specific DNA binding
EBA16_00460	COG3550	peptidyl-serine autophosphorylation
EBA16_00465	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
EBA16_00470	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EBA16_00485	COG1125	glycine betaine transport
EBA16_00485	COG0517	IMP dehydrogenase activity
EBA16_00500	COG1119	ATPase activity
EBA16_00515	COG1752	Esterase of the alpha-beta hydrolase superfamily
EBA16_00525	COG1522	sequence-specific DNA binding
EBA16_00530	COG3186	Phenylalanine-4-hydroxylase
EBA16_00560	COG1609	Transcriptional regulator
EBA16_00600	COG0366	Alpha amylase catalytic
EBA16_00605	COG0366	Alpha amylase catalytic
EBA16_00615	COG3039	Transposase
EBA16_00625	COG0183	Belongs to the thiolase family
EBA16_00665	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EBA16_00670	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EBA16_00685	COG0028	Belongs to the TPP enzyme family
EBA16_00690	COG4191	Histidine kinase
EBA16_00715	COG3039	Transposase
EBA16_00725	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EBA16_00740	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EBA16_00745	COG3177	Filamentation induced by cAMP protein fic
EBA16_00750	COG0596	Alpha beta hydrolase
EBA16_00765	COG0318	PFAM AMP-dependent synthetase and ligase
EBA16_00770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EBA16_00785	COG1181	Belongs to the D-alanine--D-alanine ligase family
EBA16_00815	COG0564	pseudouridine synthase activity
EBA16_00845	COG0339	signal peptide processing
EBA16_00900	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EBA16_00905	COG1960	acyl-CoA dehydrogenase activity
EBA16_00960	COG0697	spore germination
EBA16_00970	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EBA16_00975	COG1846	Transcriptional regulator
EBA16_00980	COG1764	response to oxidative stress
EBA16_01005	COG3501	Rhs element vgr protein
EBA16_01030	COG0656	L-ascorbic acid biosynthetic process
EBA16_01045	COG2130	NADP-dependent
EBA16_01060	COG1187	pseudouridine synthase activity
EBA16_01075	COG1643	Atp-dependent helicase
EBA16_01085	COG4807	Protein conserved in bacteria
EBA16_01090	COG2072	flavoprotein involved in K transport
EBA16_01110	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EBA16_01115	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EBA16_01155	COG3039	Transposase
EBA16_01200	COG0084	hydrolase, TatD family'
EBA16_01220	COG0583	DNA-binding transcription factor activity
EBA16_01225	COG2814	Major facilitator Superfamily
EBA16_01235	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EBA16_01240	COG1902	pentaerythritol trinitrate reductase activity
EBA16_01270	COG0745	RESPONSE REGULATOR receiver
EBA16_01290	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EBA16_01295	COG0583	DNA-binding transcription factor activity
EBA16_01325	COG0702	epimerase
EBA16_01330	COG1733	regulation of RNA biosynthetic process
EBA16_01365	COG3039	Transposase
EBA16_01385	COG3501	Rhs element vgr protein
EBA16_01410	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EBA16_01480	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EBA16_01485	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EBA16_01495	COG3485	protocatechuate 3,4-dioxygenase
EBA16_01500	COG3485	protocatechuate 3,4-dioxygenase
EBA16_01515	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EBA16_01520	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EBA16_01535	COG1414	Transcriptional regulator
EBA16_01625	COG1040	competence protein
EBA16_01630	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EBA16_01730	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EBA16_01805	COG3264	Mechanosensitive ion channel
EBA16_01805	COG1511	domain protein
EBA16_01815	COG3039	Transposase
EBA16_01820	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EBA16_01830	COG2354	Protein conserved in bacteria
EBA16_01840	COG3706	GGDEF domain
EBA16_01840	COG0745	RESPONSE REGULATOR receiver
EBA16_01855	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EBA16_01880	COG0702	epimerase
EBA16_01890	COG1028	Short-chain dehydrogenase reductase Sdr
EBA16_01935	COG0513	Belongs to the DEAD box helicase family
EBA16_01945	COG3039	Transposase
EBA16_01975	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EBA16_01990	COG3104	oligopeptide transport
EBA16_02020	COG1320	monovalent cation:proton antiporter activity
EBA16_02025	COG2212	antiporter activity
EBA16_02035	COG0651	ATP synthesis coupled electron transport
EBA16_02040	COG1006	Multisubunit Na H antiporter MnhC subunit
EBA16_02045	COG2111	Na H antiporter
EBA16_02045	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EBA16_02080	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EBA16_02090	COG0456	acetyltransferase
EBA16_02135	COG0134	indole-3-glycerol-phosphate synthase activity
EBA16_02145	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EBA16_02190	COG2906	2 iron, 2 sulfur cluster binding
EBA16_02240	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
EBA16_02260	COG2814	Major facilitator Superfamily
EBA16_02270	COG2814	Major facilitator Superfamily
EBA16_02275	COG1289	transmembrane transporter activity
EBA16_02285	COG0151	Belongs to the GarS family
EBA16_02290	COG0138	bifunctional purine biosynthesis protein purh
EBA16_02295	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EBA16_02305	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EBA16_02360	COG0439	Biotin carboxylase
EBA16_02370	COG0511	ligase activity, forming carbon-carbon bonds
EBA16_02390	COG1324	tolerance protein
EBA16_02410	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EBA16_02430	COG0534	Mate efflux family protein
EBA16_02435	COG0616	signal peptide processing
EBA16_02445	COG1028	Short-chain dehydrogenase reductase Sdr
EBA16_02465	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EBA16_02465	COG1754	DNA topoisomerase type I activity
EBA16_02485	COG0758	DNA mediated transformation
EBA16_02490	COG1652	LysM domain
EBA16_02495	COG0242	peptide deformylase activity
EBA16_02505	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EBA16_02505	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EBA16_02555	COG1560	Kdo2-lipid A biosynthetic process
EBA16_02565	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EBA16_02595	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EBA16_02600	COG3118	belongs to the thioredoxin family
EBA16_02610	COG2884	Cell division ATP-binding protein ftsE
EBA16_02615	COG2177	Part of the ABC transporter FtsEX involved in
EBA16_02620	COG3437	response regulator, receiver
EBA16_02630	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EBA16_02635	COG2860	membrane
EBA16_02640	COG1252	NADH dehydrogenase
EBA16_02660	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EBA16_02680	COG3039	Transposase
EBA16_02690	COG3039	Transposase
EBA16_02700	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EBA16_02715	COG3386	PFAM SMP-30 Gluconolaconase
EBA16_02730	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EBA16_02775	COG2353	YceI-like domain
EBA16_02830	COG3501	Rhs element vgr protein
EBA16_02890	COG4221	oxidoreductase activity
EBA16_02945	COG0697	spore germination
EBA16_02950	COG4305	rare lipoprotein A
EBA16_02955	COG5297	Belongs to the glycosyl hydrolase family 6
EBA16_02965	COG1113	amino acid transport
EBA16_02975	COG0598	Magnesium transport protein CorA
EBA16_03055	COG5001	Diguanylate cyclase
EBA16_03055	COG3300	MHYT domain
EBA16_03080	COG5297	Belongs to the glycosyl hydrolase family 6
EBA16_03080	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA16_03085	COG0659	secondary active sulfate transmembrane transporter activity
EBA16_03090	COG3706	GGDEF domain
EBA16_03120	COG3275	phosphorelay sensor kinase activity
EBA16_03155	COG1505	serine-type exopeptidase activity
EBA16_03175	COG2832	Protein of unknown function (DUF454)
EBA16_03195	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EBA16_03205	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EBA16_03240	COG5001	Diguanylate cyclase
EBA16_03240	COG3300	MHYT domain
EBA16_03245	COG0308	aminopeptidase N
EBA16_03265	COG1077	Cell shape determining protein MreB Mrl
EBA16_03270	COG1792	Involved in formation and maintenance of cell shape
EBA16_03285	COG0772	Belongs to the SEDS family
EBA16_03310	COG2951	lytic endotransglycosylase activity
EBA16_03315	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EBA16_03320	COG1686	Belongs to the peptidase S11 family
EBA16_03360	COG1056	cytidyltransferase-related domain
EBA16_03360	COG1051	belongs to the nudix hydrolase family
EBA16_03395	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EBA16_03400	COG0673	inositol 2-dehydrogenase activity
EBA16_03405	COG2823	Periplasmic or secreted lipoprotein
EBA16_03410	COG4251	negative regulation of phosphorylation
EBA16_03415	COG0784	Response regulator, receiver
EBA16_03420	COG4191	Histidine kinase
EBA16_03425	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EBA16_03450	COG3039	Transposase
EBA16_03470	COG3250	beta-galactosidase activity
EBA16_03495	COG1609	Transcriptional regulator
EBA16_03500	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EBA16_03505	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EBA16_03520	COG1215	transferase activity, transferring glycosyl groups
EBA16_03525	COG1649	PFAM Uncharacterised BCR, COG1649
EBA16_03525	COG0726	polysaccharide deacetylase
EBA16_03545	COG3039	Transposase
EBA16_03630	COG2205	protein histidine kinase activity
EBA16_03635	COG0745	RESPONSE REGULATOR receiver
EBA16_03660	COG3791	Glutathione-dependent formaldehyde-activating
EBA16_03675	COG3039	Transposase
EBA16_03690	COG0488	(ABC) transporter
EBA16_03720	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EBA16_03730	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EBA16_03730	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EBA16_03760	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EBA16_03790	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EBA16_03795	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EBA16_03805	COG2205	protein histidine kinase activity
EBA16_03810	COG0745	RESPONSE REGULATOR receiver
EBA16_03840	COG0277	FAD linked oxidase domain protein
EBA16_03895	COG3116	cell division
EBA16_03910	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EBA16_03915	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EBA16_03935	COG1181	Belongs to the D-alanine--D-alanine ligase family
EBA16_03940	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EBA16_03965	COG1196	nuclear chromosome segregation
EBA16_03965	COG0741	lytic transglycosylase activity
EBA16_03965	COG0739	heme binding
EBA16_03980	COG0494	nUDIX hydrolase
EBA16_03995	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EBA16_04010	COG3321	synthase
EBA16_04010	COG1028	Short-chain dehydrogenase reductase Sdr
EBA16_04010	COG0604	alcohol dehydrogenase
EBA16_04070	COG2226	methyltransferase
EBA16_04100	COG2826	transposase and inactivated derivatives, IS30 family
EBA16_04125	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EBA16_04140	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EBA16_04150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBA16_04155	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EBA16_04165	COG0667	Aldo Keto reductase
EBA16_04195	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EBA16_04205	COG2175	clavaminate synthase activity
EBA16_04215	COG4181	ATPase activity
EBA16_04230	COG0642	Histidine kinase
EBA16_04245	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EBA16_04285	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EBA16_04310	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EBA16_04325	COG0123	including yeast histone deacetylase and acetoin utilization protein
EBA16_04330	COG2096	Adenosyltransferase
EBA16_04345	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EBA16_04350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EBA16_04370	COG1802	Transcriptional regulator
EBA16_04380	COG3384	dioxygenase
EBA16_04385	COG0583	DNA-binding transcription factor activity
EBA16_04390	COG0318	PFAM AMP-dependent synthetase and ligase
EBA16_04400	COG1024	Enoyl-CoA hydratase
EBA16_04420	COG3386	PFAM SMP-30 Gluconolaconase
EBA16_04475	COG2197	response regulator
EBA16_04485	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EBA16_04490	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EBA16_04495	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EBA16_04505	COG0583	DNA-binding transcription factor activity
EBA16_04510	COG3634	alkyl hydroperoxide reductase activity
EBA16_04520	COG2890	protein-(glutamine-N5) methyltransferase activity
EBA16_04560	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EBA16_04560	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EBA16_04575	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EBA16_04600	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EBA16_04605	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EBA16_04630	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EBA16_04640	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EBA16_04670	COG1295	ribonuclease BN
EBA16_04675	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EBA16_04680	COG1254	Belongs to the acylphosphatase family
EBA16_04695	COG0521	Mo-molybdopterin cofactor biosynthetic process
EBA16_04710	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EBA16_04735	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EBA16_04750	COG0012	GTP binding
EBA16_04780	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EBA16_04785	COG0250	Participates in transcription elongation, termination and antitermination
EBA16_04800	COG0081	regulation of translation
EBA16_04805	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EBA16_04825	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EBA16_04850	COG0051	transcription antitermination factor activity, RNA binding
EBA16_04865	COG0089	rRNA binding
EBA16_04870	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EBA16_04890	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EBA16_04895	COG0255	Belongs to the universal ribosomal protein uL29 family
EBA16_04900	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EBA16_04910	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EBA16_04920	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EBA16_04940	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EBA16_04945	COG1841	ribosomal large subunit assembly
EBA16_04950	COG0200	Binds to the 23S rRNA
EBA16_04955	COG0201	protein transport
EBA16_04960	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EBA16_04975	COG0202	RNA polymerase activity
EBA16_04980	COG0203	ribosomal protein L17
EBA16_04995	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
EBA16_05020	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EBA16_05030	COG0625	glutathione transferase activity
EBA16_05060	COG3039	Transposase
EBA16_05080	COG0446	pyridine nucleotide-disulphide oxidoreductase
EBA16_05080	COG1902	pentaerythritol trinitrate reductase activity
EBA16_05085	COG0604	alcohol dehydrogenase
EBA16_05115	COG0156	8-amino-7-oxononanoate synthase activity
EBA16_05120	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EBA16_05125	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EBA16_05130	COG4208	sulfate ABC transporter
EBA16_05135	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EBA16_05145	COG1063	alcohol dehydrogenase
EBA16_05170	COG0406	alpha-ribazole phosphatase activity
EBA16_05180	COG0285	dihydrofolate synthase activity
EBA16_05200	COG2833	Protein of unknown function (DUF455)
EBA16_05230	COG0671	phosphoesterase, PA-phosphatase related
EBA16_05235	COG0438	transferase activity, transferring glycosyl groups
EBA16_05245	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EBA16_05250	COG5002	protein histidine kinase activity
EBA16_05260	COG4783	chaperone-mediated protein folding
EBA16_05275	COG0473	3-isopropylmalate dehydrogenase activity
EBA16_05320	COG3039	Transposase
EBA16_05345	COG0544	peptidyl-prolyl cis-trans isomerase activity
EBA16_05350	COG0740	serine-type endopeptidase activity
EBA16_05385	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EBA16_05410	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EBA16_05425	COG0631	protein serine/threonine phosphatase activity
EBA16_05460	COG0859	PFAM glycosyl transferase family 9
EBA16_05470	COG1234	tRNA 3'-trailer cleavage
EBA16_05475	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EBA16_05490	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EBA16_05495	COG0314	molybdopterin synthase activity
EBA16_05530	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EBA16_05540	COG0537	adenosine 5'-monophosphoramidase activity
EBA16_05560	COG0714	Associated with various cellular activities
EBA16_05580	COG1399	metal-binding, possibly nucleic acid-binding protein
EBA16_05605	COG1028	Short-chain dehydrogenase reductase Sdr
EBA16_05620	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EBA16_05625	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EBA16_05660	COG3829	transcription factor binding
EBA16_05700	COG3039	Transposase
EBA16_05775	COG0330	HflC and HflK could
EBA16_05780	COG0330	HflC and HflK could
EBA16_05790	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EBA16_05795	COG0308	aminopeptidase N
EBA16_05810	COG0732	type I restriction modification DNA specificity domain
EBA16_05825	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
EBA16_05865	COG0328	RNA-DNA hybrid ribonuclease activity
EBA16_05865	COG0406	alpha-ribazole phosphatase activity
EBA16_05910	COG0587	DNA-directed DNA polymerase activity
EBA16_05930	COG1297	OPT oligopeptide transporter protein
EBA16_05945	COG1506	peptidase
EBA16_05945	COG0823	Involved in the tonB-independent uptake of proteins
EBA16_05955	COG1917	Cupin 2, conserved barrel domain protein
EBA16_05955	COG2207	Transcriptional regulator
EBA16_06000	COG0753	catalase activity
EBA16_06040	COG3551	Protein conserved in bacteria
EBA16_06070	COG2194	sulfuric ester hydrolase activity
EBA16_06080	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EBA16_06085	COG0745	RESPONSE REGULATOR receiver
EBA16_06090	COG0642	Histidine kinase
EBA16_06100	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EBA16_06105	COG2894	cell division
EBA16_06120	COG4585	Histidine kinase
EBA16_06125	COG2197	response regulator
EBA16_06140	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EBA16_06165	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EBA16_06230	COG3501	Rhs element vgr protein
EBA16_06240	COG2826	transposase and inactivated derivatives, IS30 family
EBA16_06265	COG3039	Transposase
EBA16_06380	COG3501	Rhs element vgr protein
EBA16_06445	COG1842	Phage shock protein A
EBA16_06470	COG0754	glutathionylspermidine amidase activity
EBA16_06550	COG0531	amino acid
EBA16_06555	COG2197	response regulator
EBA16_06570	COG1113	amino acid transport
EBA16_06600	COG3039	Transposase
EBA16_06610	COG1294	oxidase, subunit
EBA16_06620	COG2239	Acts as a magnesium transporter
EBA16_06630	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EBA16_06635	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EBA16_06650	COG3039	Transposase
EBA16_06675	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EBA16_06690	COG1137	ATPase activity
EBA16_06695	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EBA16_06705	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EBA16_06715	COG0271	Belongs to the BolA IbaG family
EBA16_06720	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EBA16_06745	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EBA16_06770	COG0628	permease
EBA16_06780	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EBA16_06785	COG3178	'Phosphotransferase
EBA16_06795	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EBA16_06800	COG1555	photosystem II stabilization
EBA16_06820	COG3039	Transposase
EBA16_06840	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EBA16_06845	COG0719	Fe-S assembly protein
EBA16_06850	COG0396	ATPase activity
EBA16_06855	COG0719	Fe-S assembly protein
EBA16_06860	COG1959	2 iron, 2 sulfur cluster binding
EBA16_06915	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EBA16_06950	COG0519	Catalyzes the synthesis of GMP from XMP
EBA16_06965	COG1678	Uncharacterized ACR, COG1678
EBA16_06975	COG0540	Belongs to the ATCase OTCase family
EBA16_06985	COG1764	response to oxidative stress
EBA16_06995	COG0384	phenazine biosynthesis protein PhzF
EBA16_07005	COG0527	aspartate kinase activity
EBA16_07035	COG3039	Transposase
EBA16_07045	COG0142	geranyltranstransferase activity
EBA16_07050	COG0629	single-stranded DNA binding
EBA16_07055	COG5001	Diguanylate cyclase
EBA16_07055	COG3706	GGDEF domain
EBA16_07055	COG2203	Gaf domain
EBA16_07055	COG4251	negative regulation of phosphorylation
EBA16_07100	COG2879	small protein
EBA16_07105	COG1966	Carbon starvation protein
EBA16_07110	COG1741	Belongs to the pirin family
EBA16_07120	COG3501	Rhs element vgr protein
EBA16_07205	COG1515	deoxyribonuclease V activity
EBA16_07225	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EBA16_07230	COG2202	Pas domain
EBA16_07230	COG2200	EAL domain
EBA16_07230	COG2199	diguanylate cyclase activity
EBA16_07235	COG0835	chemotaxis
EBA16_07240	COG0840	transmembrane signaling receptor activity
EBA16_07250	COG2198	Histidine kinase
EBA16_07250	COG0643	Histidine kinase
EBA16_07260	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EBA16_07270	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EBA16_07310	COG0735	belongs to the Fur family
EBA16_07340	COG2826	transposase and inactivated derivatives, IS30 family
EBA16_07430	COG3039	Transposase
EBA16_07495	COG5002	protein histidine kinase activity
EBA16_07495	COG5001	Diguanylate cyclase
EBA16_07500	COG1187	pseudouridine synthase activity
EBA16_07525	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EBA16_07530	COG0475	glutathione-regulated potassium exporter activity
EBA16_07535	COG5000	phosphorelay sensor kinase activity
EBA16_07535	COG5002	protein histidine kinase activity
EBA16_07540	COG0745	RESPONSE REGULATOR receiver
EBA16_07545	COG1538	Outer membrane efflux protein
EBA16_07570	COG1132	(ABC) transporter
EBA16_07595	COG3039	Transposase
EBA16_07640	COG3118	belongs to the thioredoxin family
EBA16_07670	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EBA16_07690	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EBA16_07715	COG2968	Membrane
EBA16_07725	COG1530	ribonuclease E activity
EBA16_07730	COG3164	Protein of unknown function
EBA16_07740	COG0312	modulator of DNA gyrase
EBA16_07745	COG3028	Belongs to the UPF0307 family
EBA16_07750	COG0312	modulator of DNA gyrase
EBA16_07765	COG4104	PAAR repeat-containing protein
EBA16_07775	COG0142	geranyltranstransferase activity
EBA16_07780	COG1722	exodeoxyribonuclease VII activity
EBA16_07785	COG0037	tRNA processing
EBA16_07790	COG1785	Belongs to the alkaline phosphatase family
EBA16_07795	COG1301	dicarboxylic acid transport
EBA16_07800	COG4106	trans-aconitate 2-methyltransferase activity
EBA16_07810	COG0791	NLP P60 protein
EBA16_07815	COG0791	NLP P60 protein
EBA16_07820	COG1047	Peptidyl-prolyl cis-trans
EBA16_07825	COG2311	Membrane
EBA16_07830	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA16_07860	COG3039	Transposase
EBA16_07870	COG2826	transposase and inactivated derivatives, IS30 family
EBA16_07900	COG2826	transposase and inactivated derivatives, IS30 family
EBA16_07905	COG3039	Transposase
EBA16_07920	COG0489	protein tyrosine kinase activity
EBA16_07930	COG0717	Belongs to the dCTP deaminase family
EBA16_07945	COG3039	Transposase
EBA16_07965	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EBA16_07975	COG3039	Transposase
EBA16_07985	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EBA16_08000	COG2826	transposase and inactivated derivatives, IS30 family
EBA16_08010	COG0433	COG0433 Predicted ATPase
EBA16_08040	COG2890	protein-(glutamine-N5) methyltransferase activity
EBA16_08050	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EBA16_08055	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EBA16_08090	COG0133	tryptophan synthase activity
EBA16_08165	COG1028	Short-chain dehydrogenase reductase Sdr
EBA16_08185	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EBA16_08205	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EBA16_08210	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EBA16_08215	COG1034	ATP synthesis coupled electron transport
EBA16_08220	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EBA16_08225	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EBA16_08235	COG0713	ATP synthesis coupled electron transport
EBA16_08250	COG1007	ATP synthesis coupled electron transport
EBA16_08265	COG0195	Participates in both transcription termination and antitermination
EBA16_08270	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EBA16_08285	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EBA16_08320	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EBA16_08325	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EBA16_08335	COG2095	MarC family integral membrane protein
EBA16_08350	COG3039	Transposase
EBA16_08355	COG1611	Belongs to the LOG family
EBA16_08400	COG4969	Belongs to the N-Me-Phe pilin family
EBA16_08405	COG0556	nucleotide-excision repair
EBA16_08435	COG3723	Recombinational DNA repair protein, rece pathway
EBA16_08525	COG0270	DNA (cytosine-5-)-methyltransferase activity
EBA16_08735	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EBA16_08745	COG2986	histidine ammonia-lyase
EBA16_08795	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EBA16_08800	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EBA16_08805	COG1605	Chorismate mutase
EBA16_08805	COG0077	Prephenate dehydratase
EBA16_08835	COG3039	Transposase
EBA16_08845	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EBA16_08860	COG0583	DNA-binding transcription factor activity
EBA16_08875	COG2336	PFAM SpoVT AbrB
EBA16_08915	COG0840	transmembrane signaling receptor activity
EBA16_08940	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
EBA16_08945	COG4191	Histidine kinase
EBA16_08945	COG0784	Response regulator, receiver
EBA16_08960	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EBA16_08980	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EBA16_08995	COG1595	DNA-templated transcription, initiation
EBA16_09045	COG2244	polysaccharide biosynthetic process
EBA16_09075	COG2264	protein methyltransferase activity
EBA16_09085	COG0438	transferase activity, transferring glycosyl groups
EBA16_09100	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
EBA16_09105	COG1132	(ABC) transporter
EBA16_09115	COG0477	Major facilitator Superfamily
EBA16_09135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EBA16_09150	COG1253	flavin adenine dinucleotide binding
EBA16_09165	COG0306	phosphate transporter
EBA16_09205	COG0148	phosphopyruvate hydratase activity
EBA16_09210	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EBA16_09235	COG2840	Smr protein MutS2
EBA16_09250	COG1238	metal cluster binding
EBA16_09265	COG1534	Rna-binding protein
EBA16_09275	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EBA16_09280	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EBA16_09290	COG1923	regulation of RNA biosynthetic process
EBA16_09295	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EBA16_09300	COG1546	Belongs to the CinA family
EBA16_09325	COG2137	regulation of response to DNA damage stimulus
EBA16_09335	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EBA16_09390	COG1741	Belongs to the pirin family
EBA16_09395	COG0583	DNA-binding transcription factor activity
EBA16_09420	COG0351	phosphomethylpyrimidine kinase
EBA16_09420	COG0352	thiamine-phosphate diphosphorylase activity
EBA16_09430	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EBA16_09435	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EBA16_09450	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EBA16_09460	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EBA16_09465	COG3734	2-keto-3-deoxy-galactonokinase
EBA16_09480	COG0800	Aldolase
EBA16_09505	COG1070	Carbohydrate kinase
EBA16_09515	COG0477	Major facilitator Superfamily
EBA16_09535	COG0860	N-Acetylmuramoyl-L-alanine amidase
EBA16_09550	COG0617	tRNA 3'-terminal CCA addition
EBA16_09570	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EBA16_09600	COG1472	Belongs to the glycosyl hydrolase 3 family
EBA16_09620	COG3706	GGDEF domain
EBA16_09620	COG2203	Gaf domain
EBA16_09620	COG4251	negative regulation of phosphorylation
EBA16_09620	COG5001	Diguanylate cyclase
EBA16_09630	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EBA16_09640	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
EBA16_09655	COG0671	phosphoesterase, PA-phosphatase related
EBA16_09675	COG1794	racemase activity, acting on amino acids and derivatives
EBA16_09685	COG0697	spore germination
EBA16_09690	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EBA16_09715	COG1012	belongs to the aldehyde dehydrogenase family
EBA16_09775	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EBA16_09790	COG0124	histidyl-tRNA synthetase
EBA16_09845	COG0140	phosphoribosyl-ATP diphosphatase activity
EBA16_09845	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EBA16_09875	COG0235	Class ii aldolase
EBA16_09880	COG0531	amino acid
EBA16_09885	COG0531	amino acid
EBA16_09895	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EBA16_09900	COG0277	FAD linked oxidase domain protein
EBA16_09980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EBA16_09985	COG2258	MOSC domain
EBA16_09990	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EBA16_09995	COG0505	Belongs to the CarA family
EBA16_10005	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EBA16_10010	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EBA16_10020	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EBA16_10035	COG3279	Response regulator of the LytR AlgR family
EBA16_10060	COG0784	Response regulator, receiver
EBA16_10060	COG2205	protein histidine kinase activity
EBA16_10060	COG2198	Histidine kinase
EBA16_10065	COG1024	Enoyl-CoA hydratase
EBA16_10070	COG0318	PFAM AMP-dependent synthetase and ligase
EBA16_10100	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EBA16_10130	COG0840	transmembrane signaling receptor activity
EBA16_10140	COG0835	chemotaxis
EBA16_10155	COG0840	transmembrane signaling receptor activity
EBA16_10160	COG0840	transmembrane signaling receptor activity
EBA16_10165	COG0840	transmembrane signaling receptor activity
EBA16_10180	COG0840	transmembrane signaling receptor activity
EBA16_10190	COG0840	transmembrane signaling receptor activity
EBA16_10195	COG0840	transmembrane signaling receptor activity
EBA16_10225	COG0840	transmembrane signaling receptor activity
EBA16_10230	COG2826	transposase and inactivated derivatives, IS30 family
EBA16_10250	COG0745	RESPONSE REGULATOR receiver
EBA16_10260	COG0835	chemotaxis
EBA16_10265	COG1192	Involved in chromosome partitioning
EBA16_10270	COG1360	Flagellar Motor Protein
EBA16_10275	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EBA16_10295	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EBA16_10335	COG3039	Transposase
EBA16_10400	COG0643	Histidine kinase
EBA16_10400	COG2198	Histidine kinase
EBA16_10420	COG0455	bacterial-type flagellum organization
EBA16_10445	COG5001	Diguanylate cyclase
EBA16_10445	COG3300	MHYT domain
EBA16_10450	COG3300	MHYT domain
EBA16_10450	COG5001	Diguanylate cyclase
EBA16_10455	COG1684	flagellar biosynthetic protein fliR
EBA16_10460	COG1987	bacterial-type flagellum assembly
EBA16_10470	COG3190	flagellar
EBA16_10520	COG1677	Flagellar hook-basal body complex protein FliE
EBA16_10555	COG1028	Short-chain dehydrogenase reductase Sdr
EBA16_10565	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EBA16_10580	COG2204	response regulator
EBA16_10585	COG2201	protein-glutamate methylesterase activity
EBA16_10615	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EBA16_10620	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EBA16_10635	COG1705	Flagellar rod assembly protein muramidase FlgJ
EBA16_10635	COG3951	Flagellar rod assembly protein muramidase FlgJ
EBA16_10640	COG1706	bacterial-type flagellum-dependent cell motility
EBA16_10645	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EBA16_10650	COG4786	Flagellar basal body rod
EBA16_10660	COG4787	bacterial-type flagellum-dependent cell motility
EBA16_10665	COG1749	Flagellar hook protein flgE
EBA16_10670	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EBA16_10675	COG1558	bacterial-type flagellum-dependent cell motility
EBA16_10685	COG0784	Response regulator, receiver
EBA16_10685	COG0835	chemotaxis
EBA16_10705	COG5002	protein histidine kinase activity
EBA16_10715	COG4585	Histidine kinase
EBA16_10750	COG0482	sulfurtransferase activity
EBA16_10760	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EBA16_10765	COG0542	response to heat
EBA16_10770	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EBA16_10790	COG0492	ferredoxin-NADP+ reductase activity
EBA16_10795	COG1674	ftsk spoiiie
EBA16_10820	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EBA16_10840	COG0038	chloride channel
EBA16_10845	COG0183	Belongs to the thiolase family
EBA16_10850	COG1024	Enoyl-CoA hydratase
EBA16_10850	COG1250	3-hydroxyacyl-CoA dehydrogenase
EBA16_10860	COG0105	UTP biosynthetic process
EBA16_10885	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EBA16_10890	COG1160	GTP binding
EBA16_10895	COG0303	'Molybdopterin
EBA16_10905	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EBA16_10915	COG2826	transposase and inactivated derivatives, IS30 family
EBA16_10940	COG0746	molybdenum cofactor guanylyltransferase activity
EBA16_10965	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EBA16_10965	COG1648	precorrin-2 dehydrogenase activity
EBA16_11005	COG3039	Transposase
EBA16_11030	COG5001	Diguanylate cyclase
EBA16_11050	COG4566	intracellular signal transduction
EBA16_11090	COG3501	Rhs element vgr protein
EBA16_11175	COG1024	Enoyl-CoA hydratase
EBA16_11180	COG1024	Enoyl-CoA hydratase
EBA16_11190	COG1024	Enoyl-CoA hydratase
EBA16_11205	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EBA16_11315	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EBA16_11320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EBA16_11380	COG1858	cytochrome C peroxidase
EBA16_11410	COG0515	serine threonine protein kinase
EBA16_11415	COG0631	protein serine/threonine phosphatase activity
EBA16_11450	COG3501	Rhs element vgr protein
EBA16_11475	COG2826	transposase and inactivated derivatives, IS30 family
EBA16_11490	COG3039	Transposase
EBA16_11575	COG3039	Transposase
EBA16_11590	COG2154	pterin-4-alpha-carbinolamine dehydratase
EBA16_11605	COG3064	Membrane
EBA16_11615	COG1530	ribonuclease E activity
EBA16_11650	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EBA16_11700	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EBA16_11725	COG0811	peptide transport
EBA16_11750	COG4591	ABC-type transport system involved in lipoprotein release permease component
EBA16_11765	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EBA16_11780	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EBA16_11795	COG0354	folic acid binding
EBA16_11810	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EBA16_11820	COG0363	glucosamine-6-phosphate deaminase activity
EBA16_11825	COG0129	dihydroxy-acid dehydratase activity
EBA16_11830	COG0800	Aldolase
EBA16_11910	COG0784	Response regulator, receiver
EBA16_11910	COG2205	protein histidine kinase activity
EBA16_11925	COG2183	response to ionizing radiation
EBA16_11935	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA16_11935	COG0723	plastoquinol--plastocyanin reductase activity
EBA16_11950	COG3243	poly(R)-hydroxyalkanoic acid synthase
EBA16_11960	COG1183	phosphatidylcholine synthase activity
EBA16_11965	COG1028	Short-chain dehydrogenase reductase Sdr
EBA16_11980	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EBA16_11990	COG0668	transmembrane transport
EBA16_12000	COG0590	tRNA wobble adenosine to inosine editing
EBA16_12005	COG1321	iron dependent repressor
EBA16_12010	COG1914	H( )-stimulated, divalent metal cation uptake system
EBA16_12040	COG0583	DNA-binding transcription factor activity
EBA16_12065	COG0583	DNA-binding transcription factor activity
EBA16_12070	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EBA16_12080	COG0519	Catalyzes the synthesis of GMP from XMP
EBA16_12080	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EBA16_12105	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EBA16_12115	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EBA16_12120	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EBA16_12135	COG0539	negative regulation of cytoplasmic translation
EBA16_12140	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EBA16_12145	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EBA16_12155	COG2957	Belongs to the agmatine deiminase family
EBA16_12165	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EBA16_12190	COG0395	ABC-type sugar transport system, permease component
EBA16_12195	COG1175	transmembrane transport
EBA16_12225	COG2350	Protein conserved in bacteria
EBA16_12230	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EBA16_12235	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EBA16_12240	COG1187	pseudouridine synthase activity
EBA16_12260	COG0436	Aminotransferase
EBA16_12265	COG4133	protoheme IX ABC transporter activity
EBA16_12315	COG1278	Cold shock
EBA16_12325	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EBA16_12330	COG4988	ABC transporter
EBA16_12340	COG1271	oxidase subunit
EBA16_12410	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EBA16_12415	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EBA16_12420	COG0137	argininosuccinate synthase activity
EBA16_12425	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EBA16_12440	COG2166	iron-sulfur cluster assembly
EBA16_12455	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EBA16_12465	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EBA16_12480	COG4302	ethanolamine ammonia-lyase activity
EBA16_12495	COG4677	pectinesterase activity
EBA16_12530	COG0402	S-adenosylhomocysteine deaminase activity
EBA16_12550	COG1509	lysine 2,3-aminomutase activity
EBA16_12555	COG3300	MHYT domain
EBA16_12555	COG5001	Diguanylate cyclase
EBA16_12570	COG0483	inositol monophosphate 1-phosphatase activity
EBA16_12605	COG0513	Belongs to the DEAD box helicase family
EBA16_12615	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EBA16_12625	COG0625	glutathione transferase activity
EBA16_12640	COG4681	YaeQ
EBA16_12645	COG2081	HI0933 family
EBA16_12650	COG5001	Diguanylate cyclase
EBA16_12650	COG1716	ATPase activity
EBA16_12655	COG0501	Belongs to the peptidase M48B family
EBA16_12665	COG1028	Short-chain dehydrogenase reductase Sdr
EBA16_12690	COG0860	N-Acetylmuramoyl-L-alanine amidase
EBA16_12695	COG0802	atpase or kinase
EBA16_12700	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EBA16_12700	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EBA16_12705	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EBA16_12725	COG3039	Transposase
EBA16_12735	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EBA16_12785	COG0835	chemotaxis
EBA16_12790	COG0840	transmembrane signaling receptor activity
EBA16_12820	COG2969	positive regulation of protein catabolic process
EBA16_12825	COG0625	glutathione transferase activity
EBA16_12830	COG2857	Cytochrome c1
EBA16_12835	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EBA16_12840	COG0723	plastoquinol--plastocyanin reductase activity
EBA16_12850	COG0741	lytic transglycosylase activity
EBA16_12875	COG1702	phosphate starvation-inducible protein PhoH
EBA16_12895	COG4535	Mg2 and Co2 transporter CorC
EBA16_12910	COG1012	belongs to the aldehyde dehydrogenase family
EBA16_12915	COG1177	transmembrane transport
EBA16_12920	COG1176	ABC-type spermidine putrescine transport system, permease component I
EBA16_12930	COG3842	ATPase activity
EBA16_12960	COG3039	Transposase
EBA16_12985	COG0174	glutamine synthetase
EBA16_12990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA16_12995	COG0745	RESPONSE REGULATOR receiver
EBA16_12995	COG3706	GGDEF domain
EBA16_13000	COG0477	Major facilitator Superfamily
EBA16_13010	COG0243	molybdopterin cofactor binding
EBA16_13035	COG1121	(ABC) transporter
EBA16_13045	COG2733	membrane
EBA16_13050	COG2205	protein histidine kinase activity
EBA16_13050	COG5002	protein histidine kinase activity
EBA16_13050	COG0784	Response regulator, receiver
EBA16_13060	COG3039	Transposase
EBA16_13110	COG3039	Transposase
EBA16_13120	COG2902	Dehydrogenase
EBA16_13130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EBA16_13135	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EBA16_13150	COG1609	Transcriptional regulator
EBA16_13155	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EBA16_13155	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EBA16_13160	COG1105	Belongs to the carbohydrate kinase PfkB family
EBA16_13165	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EBA16_13165	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EBA16_13175	COG3501	Rhs element vgr protein
EBA16_13215	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EBA16_13225	COG1862	Preprotein translocase
EBA16_13295	COG0405	Gamma-glutamyltransferase
EBA16_13300	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EBA16_13320	COG0742	ribosomal rna small subunit methyltransferase
EBA16_13325	COG0326	Molecular chaperone. Has ATPase activity
EBA16_13370	COG4206	TonB-dependent receptor
EBA16_13425	COG3039	Transposase
EBA16_13430	COG3039	Transposase
EBA16_13440	COG0531	amino acid
EBA16_13455	COG0006	proline dipeptidase activity
EBA16_13465	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EBA16_13480	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA16_13485	COG3938	Belongs to the proline racemase family
EBA16_13495	COG0552	protein localization to endoplasmic reticulum
EBA16_13510	COG1194	a g-specific adenine glycosylase
EBA16_13520	COG0784	Response regulator, receiver
EBA16_13520	COG4191	Histidine kinase
EBA16_13525	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EBA16_13550	COG3040	lipid binding
EBA16_13560	COG1960	acyl-CoA dehydrogenase activity
EBA16_13610	COG0438	transferase activity, transferring glycosyl groups
EBA16_13615	COG0438	transferase activity, transferring glycosyl groups
EBA16_13660	COG0776	regulation of translation
EBA16_13670	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EBA16_13675	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EBA16_13680	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EBA16_13685	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EBA16_13725	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EBA16_13730	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EBA16_13735	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EBA16_13740	COG3115	cell septum assembly
EBA16_13765	COG0316	Belongs to the HesB IscA family
EBA16_13800	COG0288	reversible hydration of carbon dioxide
EBA16_13825	COG3844	kynureninase activity
EBA16_13835	COG2925	Exonuclease
EBA16_13845	COG0667	Aldo Keto reductase
EBA16_13860	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EBA16_13920	COG0494	nUDIX hydrolase
EBA16_13930	COG1024	Enoyl-CoA hydratase
EBA16_13940	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EBA16_13945	COG0659	secondary active sulfate transmembrane transporter activity
EBA16_13970	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EBA16_13975	COG0573	inorganic phosphate transmembrane transporter activity
EBA16_13980	COG0581	inorganic phosphate transmembrane transporter activity
EBA16_13990	COG0704	Plays a role in the regulation of phosphate uptake
EBA16_14000	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EBA16_14010	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EBA16_14025	COG0557	exoribonuclease II activity
EBA16_14055	COG1960	acyl-CoA dehydrogenase activity
EBA16_14065	COG0646	methionine synthase
EBA16_14065	COG1410	methionine synthase
EBA16_14070	COG1410	methionine synthase
EBA16_14070	COG0646	methionine synthase
EBA16_14080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBA16_14120	COG0386	Belongs to the glutathione peroxidase family
EBA16_14130	COG1725	Transcriptional regulator
EBA16_14135	COG1131	(ABC) transporter
EBA16_14175	COG3039	Transposase
EBA16_14205	COG2850	peptidyl-arginine hydroxylation
EBA16_14240	COG1132	(ABC) transporter
EBA16_14270	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EBA16_14285	COG0443	Heat shock 70 kDa protein
EBA16_14300	COG0497	DNA recombination
EBA16_14310	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EBA16_14320	COG2914	Belongs to the UPF0125 (RnfH) family
EBA16_14330	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EBA16_14355	COG3039	Transposase
EBA16_14410	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EBA16_14420	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EBA16_14425	COG0174	glutamine synthetase
EBA16_14455	COG3706	GGDEF domain
EBA16_14490	COG0415	Belongs to the DNA photolyase family
EBA16_14495	COG0305	Participates in initiation and elongation during chromosome replication
EBA16_14505	COG0367	asparagine synthase
EBA16_14535	COG0084	hydrolase, TatD family'
EBA16_14540	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EBA16_14580	COG0840	transmembrane signaling receptor activity
EBA16_14595	COG3039	Transposase
EBA16_14610	COG3039	Transposase
EBA16_14645	COG0386	Belongs to the glutathione peroxidase family
EBA16_14745	COG2814	Major facilitator Superfamily
EBA16_14750	COG1566	PFAM secretion protein HlyD family protein
EBA16_14765	COG2207	Transcriptional regulator
EBA16_14795	COG4774	siderophore transport
EBA16_14805	COG0367	asparagine synthase
EBA16_14810	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EBA16_14820	COG1393	Belongs to the ArsC family
EBA16_14840	COG0024	Methionine aminopeptidase
EBA16_14905	COG0575	Belongs to the CDS family
EBA16_14910	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EBA16_14915	COG0750	zinc metalloprotease
EBA16_14930	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EBA16_14960	COG0825	malonyl-CoA metabolic process
EBA16_15035	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EBA16_15050	COG2040	homocysteine
EBA16_15055	COG0833	amino acid
EBA16_15060	COG0346	lactoylglutathione lyase activity
EBA16_15080	COG2878	Part of a membrane complex involved in electron transport
EBA16_15100	COG1595	DNA-templated transcription, initiation
EBA16_15125	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EBA16_15140	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EBA16_15145	COG0251	oxidation-reduction process
EBA16_15155	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EBA16_15155	COG0392	lysyltransferase activity
EBA16_15195	COG2814	Major facilitator Superfamily
EBA16_15200	COG1902	pentaerythritol trinitrate reductase activity
EBA16_15215	COG2824	Alkylphosphonate utilization operon protein PhnA
EBA16_15225	COG1047	Peptidyl-prolyl cis-trans
EBA16_15270	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EBA16_15285	COG1451	nucleotide metabolic process
EBA16_15305	COG0183	Belongs to the thiolase family
EBA16_15320	COG0745	RESPONSE REGULATOR receiver
EBA16_15320	COG3706	GGDEF domain
EBA16_15335	COG1793	dna ligase
EBA16_15335	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EBA16_15345	COG1793	dna ligase
EBA16_15350	COG1201	RNA secondary structure unwinding
EBA16_15370	COG1278	Cold shock
EBA16_15375	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EBA16_15390	COG3046	protein related to deoxyribodipyrimidine photolyase
EBA16_15395	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
EBA16_15450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EBA16_15465	COG1250	3-hydroxyacyl-CoA dehydrogenase
EBA16_15465	COG1024	Enoyl-CoA hydratase
EBA16_15485	COG1024	Enoyl-CoA hydratase
EBA16_15490	COG1960	acyl-CoA dehydrogenase activity
EBA16_15565	COG2353	YceI-like domain
EBA16_15590	COG1760	l-serine dehydratase
EBA16_15600	COG0626	cystathionine gamma-synthase activity
EBA16_15605	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EBA16_15610	COG0739	heme binding
EBA16_15620	COG1272	protein, Hemolysin III
EBA16_15640	COG0517	IMP dehydrogenase activity
EBA16_15640	COG0516	GMP reductase activity
EBA16_15645	COG0463	Glycosyl transferase, family 2
EBA16_15655	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EBA16_15665	COG4771	TonB-dependent receptor
EBA16_15670	COG1309	transcriptional regulator
EBA16_15680	COG1960	acyl-CoA dehydrogenase activity
EBA16_15720	COG0330	HflC and HflK could
EBA16_15730	COG1742	UPF0060 membrane protein
EBA16_15735	COG3956	TIGRFAM MazG family protein
EBA16_15745	COG0494	nUDIX hydrolase
EBA16_15755	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EBA16_15760	COG0837	glucose binding
EBA16_15775	COG1388	LysM domain
EBA16_15775	COG3858	chitin binding
EBA16_15795	COG1472	Belongs to the glycosyl hydrolase 3 family
EBA16_15820	COG2801	Transposase and inactivated derivatives
EBA16_15830	COG2826	transposase and inactivated derivatives, IS30 family
EBA16_15845	COG3039	Transposase
EBA16_15900	COG3537	Alpha-1,2-mannosidase
EBA16_15945	COG3142	Participates in the control of copper homeostasis
EBA16_15950	COG1446	asparaginase
EBA16_15960	COG2304	oxidoreductase activity
EBA16_15990	COG0840	transmembrane signaling receptor activity
EBA16_15995	COG0835	chemotaxis
EBA16_16010	COG0189	ligase activity
EBA16_16020	COG1397	ADP-ribosylglycohydrolase
EBA16_16030	COG1199	ATP-dependent helicase activity
EBA16_16040	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EBA16_16055	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EBA16_16105	COG1643	Atp-dependent helicase
EBA16_16110	COG0783	Belongs to the Dps family
EBA16_16125	COG0514	ATP-dependent DNA helicase (RecQ)
EBA16_16140	COG3039	Transposase
EBA16_16155	COG1187	pseudouridine synthase activity
EBA16_16205	COG0602	queuosine metabolic process
EBA16_16215	COG2885	chlorophyll binding
EBA16_16220	COG0823	Involved in the tonB-independent uptake of proteins
EBA16_16230	COG0848	biopolymer transport protein
EBA16_16240	COG0824	Thioesterase
EBA16_16260	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EBA16_16280	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EBA16_16295	COG0477	Major facilitator Superfamily
EBA16_16330	COG0488	(ABC) transporter
EBA16_16360	COG4651	solute:proton antiporter activity
EBA16_16360	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EBA16_16390	COG0640	Transcriptional regulator
EBA16_16405	COG4772	TonB-dependent receptor
EBA16_16415	COG4264	IucA IucC family
EBA16_16420	COG2814	Major facilitator Superfamily
EBA16_16430	COG0019	diaminopimelate decarboxylase activity
EBA16_16485	COG4206	TonB-dependent receptor
EBA16_16520	COG0542	response to heat
EBA16_16545	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EBA16_16555	COG0534	Mate efflux family protein
EBA16_16605	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EBA16_16615	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EBA16_16655	COG2172	sigma factor antagonist activity
EBA16_16660	COG1366	Belongs to the anti-sigma-factor antagonist family
EBA16_16665	COG1366	Belongs to the anti-sigma-factor antagonist family
EBA16_16675	COG0326	Molecular chaperone. Has ATPase activity
EBA16_16680	COG2207	Transcriptional regulator
EBA16_16735	COG3209	COG3209 Rhs family protein
EBA16_16745	COG3209	COG3209 Rhs family protein
EBA16_16755	COG3501	Rhs element vgr protein
EBA16_16765	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EBA16_16770	COG1845	cytochrome c oxidase, subunit III
EBA16_16775	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EBA16_16795	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EBA16_16810	COG0728	peptidoglycan biosynthetic process
EBA16_16815	COG0268	Binds directly to 16S ribosomal RNA
EBA16_16835	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EBA16_16840	COG0824	Thioesterase
EBA16_16855	COG1946	Acyl-CoA thioesterase
EBA16_16865	COG1595	DNA-templated transcription, initiation
EBA16_16920	COG1877	trehalose-phosphatase activity
EBA16_16925	COG3387	PFAM Glycoside hydrolase 15-related
EBA16_16960	COG0564	pseudouridine synthase activity
EBA16_16965	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EBA16_16970	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EBA16_16970	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EBA16_16985	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EBA16_17030	COG2194	sulfuric ester hydrolase activity
EBA16_17035	COG4969	Belongs to the N-Me-Phe pilin family
EBA16_17045	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EBA16_17050	COG0237	dephospho-CoA kinase activity
EBA16_17055	COG2205	protein histidine kinase activity
EBA16_17060	COG0745	RESPONSE REGULATOR receiver
EBA16_17080	COG3039	Transposase
EBA16_17095	COG3039	Transposase
EBA16_17110	COG2801	Transposase and inactivated derivatives
EBA16_17120	COG3039	Transposase
EBA16_17160	COG3273	potassium ion transport
EBA16_17160	COG0471	metal ion transport
EBA16_17190	COG1970	mechanosensitive ion channel activity
EBA16_17225	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EBA16_17235	COG0308	aminopeptidase N
EBA16_17240	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EBA16_17250	COG2895	sulfate adenylyltransferase (ATP) activity
EBA16_17250	COG0529	Catalyzes the synthesis of activated sulfate
EBA16_17260	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EBA16_17290	COG0784	Response regulator, receiver
EBA16_17290	COG2198	Histidine kinase
EBA16_17290	COG2205	protein histidine kinase activity
EBA16_17330	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EBA16_17335	COG3588	fructose-bisphosphate aldolase
EBA16_17345	COG0469	pyruvate kinase activity
EBA16_17370	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EBA16_17385	COG3453	Protein conserved in bacteria
EBA16_17385	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EBA16_17390	COG0725	ABC transporter, periplasmic molybdate-binding protein
EBA16_17395	COG4149	molybdate abc transporter
EBA16_17400	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EBA16_17420	COG0642	Histidine kinase
EBA16_17425	COG0745	RESPONSE REGULATOR receiver
EBA16_17435	COG1028	Short-chain dehydrogenase reductase Sdr
EBA16_17445	COG1022	Amp-dependent synthetase and ligase
EBA16_17470	COG1376	ErfK ybiS ycfS ynhG family protein
EBA16_17475	COG0739	heme binding
EBA16_17490	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EBA16_17495	COG1301	dicarboxylic acid transport
EBA16_17515	COG2304	oxidoreductase activity
EBA16_17535	COG0714	Associated with various cellular activities
EBA16_17570	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EBA16_17595	COG0254	rRNA binding
EBA16_17605	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EBA16_17615	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EBA16_17620	COG1758	RNA polymerase activity
EBA16_17635	COG1561	YicC-like family, N-terminal region
EBA16_17655	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EBA16_17685	COG0006	proline dipeptidase activity
EBA16_17730	COG2912	Transglutaminase-like superfamily
EBA16_17735	COG1773	rubredoxin
EBA16_17740	COG0352	thiamine-phosphate diphosphorylase activity
EBA16_17765	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
EBA16_17805	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EBA16_17830	COG0671	phosphoesterase, PA-phosphatase related
EBA16_17845	COG3781	membrane
EBA16_17855	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EBA16_17870	COG3039	Transposase
EBA16_17885	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
EBA16_17895	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EBA16_17920	COG3710	Transcriptional regulator
EBA16_17965	COG2226	methyltransferase
EBA16_17995	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EBA16_18000	COG1538	Outer membrane efflux protein
EBA16_18005	COG1519	Transferase
EBA16_18010	COG1560	Kdo2-lipid A biosynthetic process
EBA16_18030	COG3039	Transposase
EBA16_18040	COG2826	transposase and inactivated derivatives, IS30 family
EBA16_18105	COG3039	Transposase
EBA16_18120	COG0280	phosphate acetyltransferase
EBA16_18120	COG0281	malic enzyme
EBA16_18140	COG4191	Histidine kinase
EBA16_18155	COG0583	DNA-binding transcription factor activity
EBA16_18175	COG2197	response regulator
EBA16_18185	COG0642	Histidine kinase
EBA16_18205	COG2851	Citrate transporter
EBA16_18210	COG1028	Short-chain dehydrogenase reductase Sdr
EBA16_18220	COG1609	Transcriptional regulator
EBA16_18230	COG2211	Major facilitator Superfamily
EBA16_18260	COG0436	Aminotransferase
EBA16_18280	COG0726	polysaccharide deacetylase
EBA16_18285	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EBA16_18305	COG0402	S-adenosylhomocysteine deaminase activity
EBA16_18355	COG0242	peptide deformylase activity
EBA16_18360	COG3039	Transposase
EBA16_18395	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EBA16_18455	COG2188	Transcriptional regulator
EBA16_18470	COG1450	Type ii and iii secretion system protein
EBA16_18485	COG3166	PFAM Fimbrial assembly family protein
EBA16_18490	COG3156	type II secretion system protein K
EBA16_18495	COG4795	General secretion pathway protein
EBA16_18500	COG2165	general secretion pathway protein
EBA16_18505	COG4970	Tfp pilus assembly protein FimT
EBA16_18510	COG2165	general secretion pathway protein
EBA16_18515	COG1459	type II secretion system
EBA16_18525	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EBA16_18530	COG1404	Belongs to the peptidase S8 family
EBA16_18535	COG5295	Hep Hag repeat protein
EBA16_18545	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EBA16_18545	COG0047	phosphoribosylformylglycinamidine synthase activity
EBA16_18555	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EBA16_18560	COG4974	Belongs to the 'phage' integrase family
EBA16_18575	COG0795	lipopolysaccharide-transporting ATPase activity
EBA16_18610	COG0525	valine-tRNA ligase activity
EBA16_18640	COG2826	transposase and inactivated derivatives, IS30 family
EBA16_18650	COG2826	transposase and inactivated derivatives, IS30 family
EBA16_18675	COG1183	phosphatidylcholine synthase activity
EBA16_18700	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EBA16_18705	COG1127	ABC transporter
EBA16_18710	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EBA16_18710	COG3218	ABC-type transport auxiliary lipoprotein component
EBA16_18755	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EBA16_18760	COG0662	Cupin 2, conserved barrel domain protein
EBA16_18760	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
EBA16_18790	COG2086	electron transfer activity
EBA16_18860	COG0626	cystathionine gamma-synthase activity
EBA16_18890	COG0625	glutathione transferase activity
EBA16_18905	COG0513	Belongs to the DEAD box helicase family
EBA16_18915	COG0720	synthase
EBA16_18930	COG1956	GAF domain-containing protein
EBA16_18940	COG0546	phosphoglycolate phosphatase activity
EBA16_18970	COG0339	signal peptide processing
EBA16_19020	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EBA16_19110	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EBA16_19120	COG0356	it plays a direct role in the translocation of protons across the membrane
EBA16_19140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EBA16_19150	COG0508	dehydrogenase complex catalyzes the overall conversion of
EBA16_19185	COG2011	ABC-type metal ion transport system permease component
EBA16_19195	COG0697	spore germination
EBA16_19230	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EBA16_19235	COG1187	pseudouridine synthase activity
EBA16_19240	COG2813	Specifically methylates the guanine in position
EBA16_19270	COG2202	Pas domain
EBA16_19270	COG2205	protein histidine kinase activity
EBA16_19295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EBA16_19300	COG1522	sequence-specific DNA binding
EBA16_19345	COG0745	RESPONSE REGULATOR receiver
EBA16_19360	COG1404	Belongs to the peptidase S8 family
EBA16_19375	COG0842	Transport permease protein
EBA16_19380	COG1131	(ABC) transporter
EBA16_19385	COG0025	NhaP-type Na H and K H
EBA16_19395	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EBA16_19405	COG1573	uracil-dna glycosylase
EBA16_19415	COG3384	dioxygenase
EBA16_19445	COG3590	peptidase
EBA16_19465	COG0531	amino acid
EBA16_19490	COG3685	Protein conserved in bacteria
EBA16_19495	COG3546	catalase activity
EBA16_19520	COG3039	Transposase
EBA16_19550	COG1271	oxidase subunit
EBA16_19555	COG1294	oxidase, subunit
EBA16_19590	COG1063	alcohol dehydrogenase
EBA16_19695	COG1473	amidohydrolase
EBA16_19700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EBA16_19705	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EBA16_19730	COG5383	Protein conserved in bacteria
EBA16_19780	COG3023	N-Acetylmuramoyl-L-alanine amidase
EBA16_19790	COG4948	Mandelate Racemase Muconate Lactonizing
EBA16_19815	COG0531	amino acid
EBA16_19835	COG4682	membrane
EBA16_19840	COG2133	pyrroloquinoline quinone binding
EBA16_19860	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EBA16_19870	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EBA16_19875	COG1610	YqeY-like protein
EBA16_19895	COG1295	ribonuclease BN
EBA16_19900	COG0358	DNA primase activity
EBA16_19960	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
EBA16_19975	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EBA16_20040	COG0739	heme binding
EBA16_20055	COG2211	Major facilitator Superfamily
EBA16_20060	COG0708	Exodeoxyribonuclease III
EBA16_20075	COG1192	Involved in chromosome partitioning
EBA16_20080	COG1475	DNA binding
EBA16_20095	COG0463	Glycosyl transferase, family 2
EBA16_20120	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EBA16_20145	COG4221	oxidoreductase activity
EBA16_20185	COG1166	arginine decarboxylase activity
EBA16_20235	COG0606	chelatase, subunit chli
EBA16_20260	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EBA16_20280	COG3039	Transposase
EBA16_20340	COG1090	epimerase
EBA16_20350	COG0642	Histidine kinase
EBA16_20365	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EBA16_20400	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EBA16_20410	COG1595	DNA-templated transcription, initiation
EBA16_20415	COG0753	catalase activity
EBA16_20440	COG0697	spore germination
EBA16_20465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EBA16_20470	COG0180	Tryptophanyl-tRNA synthetase
EBA16_20475	COG3237	CsbD-like
EBA16_20530	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EBA16_20530	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EBA16_20540	COG3228	Belongs to the MtfA family
EBA16_20555	COG2205	protein histidine kinase activity
EBA16_20560	COG0745	RESPONSE REGULATOR receiver
EBA16_20570	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EBA16_20625	COG3039	Transposase
EBA16_20630	COG1566	PFAM secretion protein HlyD family protein
EBA16_20645	COG1199	ATP-dependent helicase activity
EBA16_20690	COG0583	DNA-binding transcription factor activity
EBA16_20740	COG0625	glutathione transferase activity
EBA16_20750	COG2826	transposase and inactivated derivatives, IS30 family
EBA16_20780	COG4555	ABC transporter
EBA16_20790	COG1476	TRANSCRIPTIONal
EBA16_20810	COG1230	cation diffusion facilitator family transporter
EBA16_20815	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EBA16_20820	COG1131	(ABC) transporter
EBA16_20825	COG0842	Transport permease protein
EBA16_20835	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EBA16_20870	COG2951	lytic endotransglycosylase activity
EBA16_20885	COG1196	nuclear chromosome segregation
EBA16_20890	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EBA16_20900	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EBA16_20915	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EBA16_20915	COG0045	succinate-CoA ligase (ADP-forming) activity
EBA16_20915	COG1042	CoA-binding domain protein
EBA16_20925	COG2239	Acts as a magnesium transporter
EBA16_20950	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EBA16_20955	COG3387	PFAM Glycoside hydrolase 15-related
EBA16_20970	COG3100	YcgL domain-containing protein
EBA16_20975	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EBA16_20985	COG0463	Glycosyl transferase, family 2
EBA16_20995	COG1028	Short-chain dehydrogenase reductase Sdr
EBA16_21025	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EBA16_21040	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EBA16_21160	COG0210	DNA helicase
EBA16_21180	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EBA16_21195	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EBA16_21210	COG2159	amidohydrolase
EBA16_21215	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EBA16_21220	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EBA16_21240	COG0357	Ribosomal RNA small subunit methyltransferase G
EBA16_21245	COG3540	Alkaline phosphatase
EBA16_21255	COG2091	lysine biosynthetic process via aminoadipic acid
EBA16_21270	COG0708	Exodeoxyribonuclease III
EBA16_21285	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EBA16_21290	COG3162	membrane
EBA16_21345	COG1028	Short-chain dehydrogenase reductase Sdr
EBA16_21350	COG0179	Fumarylacetoacetate (FAA) hydrolase
EBA16_21360	COG4948	Mandelate Racemase Muconate Lactonizing
EBA16_21365	COG3254	rhamnose metabolic process
EBA16_21370	COG0738	Major facilitator superfamily
EBA16_21375	COG1414	Transcriptional regulator
EBA16_21385	COG2205	protein histidine kinase activity
EBA16_21395	COG3459	Glycosyltransferase 36 associated
EBA16_21400	COG2211	Major facilitator Superfamily
EBA16_21405	COG3265	gluconokinase activity
EBA16_21410	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EBA16_21440	COG3039	Transposase
EBA16_21450	COG3039	Transposase
EBA16_21455	COG2911	Protein conserved in bacteria
EBA16_21460	COG0729	surface antigen
EBA16_21465	COG4771	TonB-dependent receptor
EBA16_21470	COG0457	Tetratricopeptide repeat
EBA16_21480	COG0752	glycyl-tRNA synthetase alpha subunit
EBA16_21485	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EBA16_21495	COG0519	Catalyzes the synthesis of GMP from XMP
EBA16_21495	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EBA16_21505	COG0805	protein transport
EBA16_21510	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EBA16_21515	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EBA16_21525	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EBA16_21555	COG2974	May be involved in recombination
EBA16_21560	COG0037	tRNA processing
EBA16_21585	COG3661	Belongs to the glycosyl hydrolase 67 family
EBA16_21595	COG4948	Mandelate Racemase Muconate Lactonizing
EBA16_21605	COG1472	Belongs to the glycosyl hydrolase 3 family
EBA16_21610	COG0246	Mannitol dehydrogenase
EBA16_21645	COG2826	transposase and inactivated derivatives, IS30 family
EBA16_21670	COG3693	PFAM glycoside hydrolase, family 10
EBA16_21695	COG2211	Major facilitator Superfamily
EBA16_21710	COG3039	Transposase
EBA16_21745	COG2937	Belongs to the GPAT DAPAT family
EBA16_21785	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EBA16_21805	COG0210	DNA helicase
EBA16_21820	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
EBA16_21885	COG0676	glucose-6-phosphate 1-epimerase activity
EBA16_21900	COG0730	response to heat
EBA16_21935	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EBA16_21940	COG0302	gtp cyclohydrolase
EBA16_21970	COG2826	transposase and inactivated derivatives, IS30 family
EBA16_21980	COG0477	Major facilitator Superfamily
EBA16_21995	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EBA16_22040	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EBA16_22090	COG3237	CsbD-like
EBA16_22110	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBA16_22165	COG4772	TonB-dependent receptor
EBA16_22175	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EBA16_22205	COG3039	Transposase
EBA16_22255	COG0564	pseudouridine synthase activity
EBA16_22270	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EBA16_22290	COG3039	Transposase
EBA16_22310	COG3039	Transposase
EBA16_22335	COG3039	Transposase
EBA16_22410	COG1074	ATP-dependent DNA helicase activity
EBA16_22415	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EBA16_22430	COG3039	Transposase
EBA16_22435	COG3039	Transposase
EBA16_22445	COG1136	(ABC) transporter
EBA16_22465	COG1127	ABC transporter
EBA16_22470	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EBA16_22475	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EBA16_22490	COG2853	Lipoprotein
EBA16_22515	COG0386	Belongs to the glutathione peroxidase family
EBA16_22525	COG1322	Protein conserved in bacteria
EBA16_22530	COG3039	Transposase
EBA16_22555	COG1929	Belongs to the glycerate kinase type-1 family
EBA16_22560	COG2271	Major facilitator Superfamily
EBA16_22575	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EBA16_22585	COG0861	Integral membrane protein TerC family
EBA16_22600	COG0584	glycerophosphoryl diester phosphodiesterase
EBA16_22610	COG0671	phosphoesterase, PA-phosphatase related
EBA16_22615	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EBA16_22620	COG0726	polysaccharide deacetylase
EBA16_22635	COG0230	Belongs to the bacterial ribosomal protein bL34 family