locus-tag	class	description
BO993_00110	COG3039	Transposase
BO993_00150	COG3039	Transposase
BO993_00165	COG4695	Portal protein
BO993_00210	COG3179	chitinase
BO993_00405	COG1611	Belongs to the LOG family
BO993_00420	COG2095	MarC family integral membrane protein
BO993_00430	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BO993_00435	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BO993_00470	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BO993_00490	COG0195	Participates in both transcription termination and antitermination
BO993_00505	COG1007	ATP synthesis coupled electron transport
BO993_00520	COG0713	ATP synthesis coupled electron transport
BO993_00535	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BO993_00540	COG1034	ATP synthesis coupled electron transport
BO993_00545	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BO993_00550	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BO993_00570	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BO993_00590	COG1028	Short-chain dehydrogenase reductase Sdr
BO993_00610	COG3293	Transposase
BO993_00655	COG0159	tryptophan synthase activity
BO993_00700	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BO993_00705	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BO993_00715	COG2890	protein-(glutamine-N5) methyltransferase activity
BO993_00740	COG0433	COG0433 Predicted ATPase
BO993_00760	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BO993_00770	COG0412	Dienelactone hydrolase
BO993_00790	COG0489	protein tyrosine kinase activity
BO993_00825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BO993_00830	COG2311	Membrane
BO993_00835	COG1047	Peptidyl-prolyl cis-trans
BO993_00840	COG0791	NLP P60 protein
BO993_00845	COG0791	NLP P60 protein
BO993_00860	COG1301	dicarboxylic acid transport
BO993_00865	COG1785	Belongs to the alkaline phosphatase family
BO993_00870	COG0037	tRNA processing
BO993_00880	COG0142	geranyltranstransferase activity
BO993_00900	COG0312	modulator of DNA gyrase
BO993_00905	COG3028	Belongs to the UPF0307 family
BO993_00910	COG0312	modulator of DNA gyrase
BO993_00920	COG3164	Protein of unknown function
BO993_00925	COG1530	ribonuclease E activity
BO993_00935	COG2968	Membrane
BO993_00985	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BO993_01010	COG3118	belongs to the thioredoxin family
BO993_01055	COG3293	Transposase
BO993_01110	COG2801	Transposase and inactivated derivatives
BO993_01115	COG2963	transposase activity
BO993_01160	COG0471	metal ion transport
BO993_01160	COG3273	potassium ion transport
BO993_01195	COG1970	mechanosensitive ion channel activity
BO993_01215	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BO993_01245	COG0308	aminopeptidase N
BO993_01250	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BO993_01260	COG3039	Transposase
BO993_01270	COG0529	Catalyzes the synthesis of activated sulfate
BO993_01270	COG2895	sulfate adenylyltransferase (ATP) activity
BO993_01280	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BO993_01310	COG2198	Histidine kinase
BO993_01310	COG2205	protein histidine kinase activity
BO993_01310	COG0784	Response regulator, receiver
BO993_01355	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BO993_01360	COG3588	fructose-bisphosphate aldolase
BO993_01365	COG0469	pyruvate kinase activity
BO993_01375	COG0126	phosphoglycerate kinase activity
BO993_01405	COG0753	catalase activity
BO993_01430	COG2207	Transcriptional regulator
BO993_01430	COG1917	Cupin 2, conserved barrel domain protein
BO993_01455	COG1506	peptidase
BO993_01455	COG0823	Involved in the tonB-independent uptake of proteins
BO993_01480	COG1297	OPT oligopeptide transporter protein
BO993_01495	COG0587	DNA-directed DNA polymerase activity
BO993_01540	COG0328	RNA-DNA hybrid ribonuclease activity
BO993_01540	COG0406	alpha-ribazole phosphatase activity
BO993_01580	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BO993_01595	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
BO993_01600	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
BO993_01605	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BO993_01625	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
BO993_01680	COG3039	Transposase
BO993_01690	COG3039	Transposase
BO993_01730	COG3501	Rhs element vgr protein
BO993_01800	COG3179	chitinase
BO993_01820	COG3501	Rhs element vgr protein
BO993_01860	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BO993_01870	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BO993_01880	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BO993_01985	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BO993_02010	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BO993_02025	COG2197	response regulator
BO993_02030	COG4585	Histidine kinase
BO993_02045	COG2894	cell division
BO993_02050	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BO993_02060	COG0642	Histidine kinase
BO993_02065	COG0745	RESPONSE REGULATOR receiver
BO993_02070	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BO993_02080	COG2194	sulfuric ester hydrolase activity
BO993_02110	COG3551	Protein conserved in bacteria
BO993_02150	COG2801	Transposase and inactivated derivatives
BO993_02180	COG0203	ribosomal protein L17
BO993_02185	COG0202	RNA polymerase activity
BO993_02200	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BO993_02205	COG0201	protein transport
BO993_02215	COG1841	ribosomal large subunit assembly
BO993_02220	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BO993_02240	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BO993_02260	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BO993_02265	COG0255	Belongs to the universal ribosomal protein uL29 family
BO993_02270	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BO993_02295	COG0089	rRNA binding
BO993_02335	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BO993_02370	COG0250	Participates in transcription elongation, termination and antitermination
BO993_02375	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BO993_02405	COG0012	GTP binding
BO993_02420	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BO993_02445	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BO993_02460	COG0521	Mo-molybdopterin cofactor biosynthetic process
BO993_02480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BO993_02515	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BO993_02525	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BO993_02550	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BO993_02555	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BO993_02575	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BO993_02590	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BO993_02590	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BO993_02630	COG2890	protein-(glutamine-N5) methyltransferase activity
BO993_02640	COG3634	alkyl hydroperoxide reductase activity
BO993_02645	COG0583	DNA-binding transcription factor activity
BO993_02650	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BO993_02655	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BO993_02685	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BO993_02720	COG0584	glycerophosphoryl diester phosphodiesterase
BO993_02725	COG3293	Transposase
BO993_02765	COG0625	glutathione transferase activity
BO993_02795	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BO993_02905	COG3293	Transposase
BO993_02940	COG3781	membrane
BO993_02950	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BO993_02995	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BO993_03020	COG3710	Transcriptional regulator
BO993_03065	COG2226	methyltransferase
BO993_03110	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BO993_03115	COG1538	Outer membrane efflux protein
BO993_03120	COG1519	Transferase
BO993_03125	COG1560	Kdo2-lipid A biosynthetic process
BO993_03180	COG0308	aminopeptidase N
BO993_03185	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BO993_03195	COG0330	HflC and HflK could
BO993_03200	COG0330	HflC and HflK could
BO993_03220	COG0678	peroxiredoxin activity
BO993_03230	COG2826	transposase and inactivated derivatives, IS30 family
BO993_03305	COG3829	transcription factor binding
BO993_03330	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BO993_03335	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BO993_03350	COG1028	Short-chain dehydrogenase reductase Sdr
BO993_03375	COG1399	metal-binding, possibly nucleic acid-binding protein
BO993_03390	COG3039	Transposase
BO993_03425	COG1518	maintenance of DNA repeat elements
BO993_03430	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BO993_03470	COG2188	Transcriptional regulator
BO993_03485	COG1450	Type ii and iii secretion system protein
BO993_03500	COG3166	PFAM Fimbrial assembly family protein
BO993_03505	COG3156	type II secretion system protein K
BO993_03510	COG4795	General secretion pathway protein
BO993_03515	COG2165	general secretion pathway protein
BO993_03520	COG4970	Tfp pilus assembly protein FimT
BO993_03525	COG2165	general secretion pathway protein
BO993_03530	COG1459	type II secretion system
BO993_03540	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BO993_03550	COG5295	Hep Hag repeat protein
BO993_03555	COG0047	phosphoribosylformylglycinamidine synthase activity
BO993_03555	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BO993_03565	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BO993_03570	COG4974	Belongs to the 'phage' integrase family
BO993_03585	COG0795	lipopolysaccharide-transporting ATPase activity
BO993_03610	COG0525	valine-tRNA ligase activity
BO993_03630	COG2801	Transposase and inactivated derivatives
BO993_03710	COG1183	phosphatidylcholine synthase activity
BO993_03735	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BO993_03740	COG1127	ABC transporter
BO993_03745	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BO993_03745	COG3218	ABC-type transport auxiliary lipoprotein component
BO993_03780	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BO993_03785	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BO993_03785	COG0662	Cupin 2, conserved barrel domain protein
BO993_03810	COG2086	electron transfer activity
BO993_03825	COG0546	phosphoglycolate phosphatase activity
BO993_03825	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BO993_03830	COG0277	FAD linked oxidase domain protein
BO993_03845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BO993_03850	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
BO993_03885	COG0438	transferase activity, transferring glycosyl groups
BO993_03885	COG1216	Glycosyl transferase, family 2
BO993_03910	COG0626	cystathionine gamma-synthase activity
BO993_03940	COG0625	glutathione transferase activity
BO993_03950	COG0513	Belongs to the DEAD box helicase family
BO993_03960	COG0720	synthase
BO993_03975	COG1956	GAF domain-containing protein
BO993_04010	COG0339	signal peptide processing
BO993_04050	COG3293	Transposase
BO993_04065	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BO993_04070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BO993_04075	COG3842	ATPase activity
BO993_04125	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BO993_04160	COG0356	it plays a direct role in the translocation of protons across the membrane
BO993_04180	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BO993_04190	COG0508	dehydrogenase complex catalyzes the overall conversion of
BO993_04220	COG2011	ABC-type metal ion transport system permease component
BO993_04230	COG0697	spore germination
BO993_04265	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BO993_04270	COG1187	pseudouridine synthase activity
BO993_04275	COG2813	Specifically methylates the guanine in position
BO993_04305	COG2202	Pas domain
BO993_04305	COG2205	protein histidine kinase activity
BO993_04330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BO993_04335	COG1522	sequence-specific DNA binding
BO993_04380	COG0745	RESPONSE REGULATOR receiver
BO993_04395	COG1404	Belongs to the peptidase S8 family
BO993_04410	COG0842	Transport permease protein
BO993_04415	COG1131	(ABC) transporter
BO993_04420	COG0025	NhaP-type Na H and K H
BO993_04435	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
BO993_04445	COG1573	uracil-dna glycosylase
BO993_04455	COG3384	dioxygenase
BO993_04470	COG0667	Aldo Keto reductase
BO993_04485	COG3590	peptidase
BO993_04505	COG0531	amino acid
BO993_04580	COG1271	oxidase subunit
BO993_04725	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BO993_04735	COG1560	Kdo2-lipid A biosynthetic process
BO993_04785	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BO993_04785	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BO993_04795	COG0242	peptide deformylase activity
BO993_04800	COG1652	LysM domain
BO993_04805	COG0758	DNA mediated transformation
BO993_04825	COG1754	DNA topoisomerase type I activity
BO993_04825	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BO993_04845	COG1028	Short-chain dehydrogenase reductase Sdr
BO993_04855	COG0616	signal peptide processing
BO993_04860	COG0534	Mate efflux family protein
BO993_04885	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BO993_04915	COG1324	tolerance protein
BO993_04935	COG0511	ligase activity, forming carbon-carbon bonds
BO993_04945	COG0439	Biotin carboxylase
BO993_04985	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BO993_04995	COG0671	phosphoesterase, PA-phosphatase related
BO993_04995	COG2453	phosphatase
BO993_05000	COG2267	carboxylic ester hydrolase activity
BO993_05010	COG2267	carboxylic ester hydrolase activity
BO993_05015	COG3039	Transposase
BO993_05025	COG0138	bifunctional purine biosynthesis protein purh
BO993_05030	COG0151	Belongs to the GarS family
BO993_05055	COG1289	transmembrane transporter activity
BO993_05070	COG2814	Major facilitator Superfamily
BO993_05090	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BO993_05180	COG0739	heme binding
BO993_05195	COG2211	Major facilitator Superfamily
BO993_05200	COG0708	Exodeoxyribonuclease III
BO993_05215	COG1192	Involved in chromosome partitioning
BO993_05220	COG1475	DNA binding
BO993_05235	COG0463	Glycosyl transferase, family 2
BO993_05260	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BO993_05285	COG4221	oxidoreductase activity
BO993_05300	COG1414	Transcriptional regulator
BO993_05310	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BO993_05315	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BO993_05335	COG3485	protocatechuate 3,4-dioxygenase
BO993_05355	COG2801	Transposase and inactivated derivatives
BO993_05380	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BO993_05385	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BO993_05395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BO993_05395	COG1042	CoA-binding domain protein
BO993_05395	COG0045	succinate-CoA ligase (ADP-forming) activity
BO993_05405	COG2239	Acts as a magnesium transporter
BO993_05420	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BO993_05425	COG3387	PFAM Glycoside hydrolase 15-related
BO993_05440	COG3100	YcgL domain-containing protein
BO993_05445	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BO993_05455	COG0463	Glycosyl transferase, family 2
BO993_05470	COG1028	Short-chain dehydrogenase reductase Sdr
BO993_05490	COG1040	competence protein
BO993_05505	COG0628	permease
BO993_05515	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BO993_05530	COG0753	catalase activity
BO993_05580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BO993_05585	COG0180	Tryptophanyl-tRNA synthetase
BO993_05590	COG3237	CsbD-like
BO993_05645	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BO993_05645	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BO993_05670	COG2205	protein histidine kinase activity
BO993_05675	COG0745	RESPONSE REGULATOR receiver
BO993_05685	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BO993_05710	COG1566	PFAM secretion protein HlyD family protein
BO993_05730	COG1199	ATP-dependent helicase activity
BO993_05765	COG0583	DNA-binding transcription factor activity
BO993_05810	COG0625	glutathione transferase activity
BO993_05845	COG4555	ABC transporter
BO993_05855	COG1476	TRANSCRIPTIONal
BO993_05880	COG1131	(ABC) transporter
BO993_05885	COG0842	Transport permease protein
BO993_05895	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BO993_05930	COG2801	Transposase and inactivated derivatives
BO993_05935	COG3293	Transposase
BO993_05970	COG1181	Belongs to the D-alanine--D-alanine ligase family
BO993_05995	COG0564	pseudouridine synthase activity
BO993_06020	COG0339	signal peptide processing
BO993_06045	COG3254	rhamnose metabolic process
BO993_06050	COG0738	Major facilitator superfamily
BO993_06055	COG1414	Transcriptional regulator
BO993_06065	COG2205	protein histidine kinase activity
BO993_06080	COG3459	Glycosyltransferase 36 associated
BO993_06085	COG2211	Major facilitator Superfamily
BO993_06090	COG3265	gluconokinase activity
BO993_06100	COG3293	Transposase
BO993_06110	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BO993_06130	COG2963	transposase activity
BO993_06135	COG2801	Transposase and inactivated derivatives
BO993_06165	COG3293	Transposase
BO993_06195	COG1127	ABC transporter
BO993_06200	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BO993_06205	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BO993_06220	COG2853	Lipoprotein
BO993_06240	COG3293	Transposase
BO993_06300	COG3135	benzoate transporter
BO993_06305	COG3135	benzoate transporter
BO993_06325	COG0676	glucose-6-phosphate 1-epimerase activity
BO993_06345	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BO993_06355	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BO993_06360	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BO993_06365	COG1064	alcohol dehydrogenase
BO993_06400	COG2826	transposase and inactivated derivatives, IS30 family
BO993_06405	COG4773	Receptor
BO993_06420	COG1522	sequence-specific DNA binding
BO993_06425	COG3186	Phenylalanine-4-hydroxylase
BO993_06435	COG2755	lipolytic protein G-D-S-L family
BO993_06470	COG2937	Belongs to the GPAT DAPAT family
BO993_06505	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BO993_06525	COG0210	DNA helicase
BO993_06540	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
BO993_06565	COG1028	Short-chain dehydrogenase reductase Sdr
BO993_06655	COG1166	arginine decarboxylase activity
BO993_06695	COG0606	chelatase, subunit chli
BO993_06720	COG3328	transposase activity
BO993_06735	COG2801	Transposase and inactivated derivatives
BO993_06740	COG0366	Alpha amylase catalytic
BO993_06745	COG0366	Alpha amylase catalytic
BO993_06770	COG1609	Transcriptional regulator
BO993_06775	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BO993_06780	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BO993_06815	COG0493	'glutamate synthase
BO993_06820	COG0070	glutamate synthase
BO993_06820	COG0069	glutamate synthase activity
BO993_06820	COG0067	glutamate synthase
BO993_06875	COG1205	dead DEAH box helicase
BO993_06875	COG1111	helicase
BO993_06880	COG1272	protein, Hemolysin III
BO993_06920	COG1136	(ABC) transporter
BO993_06965	COG1116	anion transmembrane transporter activity
BO993_06985	COG0508	dehydrogenase complex catalyzes the overall conversion of
BO993_07005	COG3039	Transposase
BO993_07015	COG0513	Belongs to the DEAD box helicase family
BO993_07085	COG1858	cytochrome C peroxidase
BO993_07095	COG0702	epimerase
BO993_07120	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BO993_07135	COG3706	GGDEF domain
BO993_07135	COG0745	RESPONSE REGULATOR receiver
BO993_07145	COG2354	Protein conserved in bacteria
BO993_07150	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BO993_07160	COG3293	Transposase
BO993_07170	COG1511	domain protein
BO993_07170	COG3264	Mechanosensitive ion channel
BO993_07255	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BO993_07360	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BO993_07370	COG0642	Histidine kinase
BO993_07375	COG1090	epimerase
BO993_07410	COG2826	transposase and inactivated derivatives, IS30 family
BO993_07475	COG3039	Transposase
BO993_07495	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BO993_07500	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BO993_07540	COG4772	TonB-dependent receptor
BO993_07560	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BO993_07570	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BO993_07600	COG0501	Belongs to the peptidase M48B family
BO993_07610	COG0187	DNA topoisomerase II activity
BO993_07630	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BO993_07645	COG0726	polysaccharide deacetylase
BO993_07650	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BO993_07655	COG0671	phosphoesterase, PA-phosphatase related
BO993_07665	COG0584	glycerophosphoryl diester phosphodiesterase
BO993_07680	COG0861	Integral membrane protein TerC family
BO993_07685	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BO993_07700	COG2271	Major facilitator Superfamily
BO993_07705	COG1929	Belongs to the glycerate kinase type-1 family
BO993_07730	COG3328	transposase activity
BO993_07755	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BO993_07765	COG0477	Major facilitator Superfamily
BO993_07785	COG0302	gtp cyclohydrolase
BO993_07790	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BO993_07840	COG2234	aminopeptidase activity
BO993_07850	COG4942	peptidase
BO993_07855	COG0793	Belongs to the peptidase S41A family
BO993_07920	COG0386	Belongs to the glutathione peroxidase family
BO993_07930	COG1322	Protein conserved in bacteria
BO993_07935	COG0531	amino acid
BO993_07950	COG0210	DNA helicase
BO993_07965	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BO993_07970	COG0583	DNA-binding transcription factor activity
BO993_07975	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BO993_07985	COG2159	amidohydrolase
BO993_07990	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BO993_07995	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BO993_08010	COG0357	Ribosomal RNA small subunit methyltransferase G
BO993_08015	COG3540	Alkaline phosphatase
BO993_08025	COG2091	lysine biosynthetic process via aminoadipic acid
BO993_08040	COG0708	Exodeoxyribonuclease III
BO993_08055	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BO993_08060	COG3162	membrane
BO993_08105	COG3507	Belongs to the glycosyl hydrolase 43 family
BO993_08125	COG1028	Short-chain dehydrogenase reductase Sdr
BO993_08130	COG0179	Fumarylacetoacetate (FAA) hydrolase
BO993_08135	COG4948	Mandelate Racemase Muconate Lactonizing
BO993_08140	COG4807	Protein conserved in bacteria
BO993_08145	COG1643	Atp-dependent helicase
BO993_08160	COG1187	pseudouridine synthase activity
BO993_08170	COG0667	Aldo Keto reductase
BO993_08175	COG2130	NADP-dependent
BO993_08180	COG0656	L-ascorbic acid biosynthetic process
BO993_08200	COG2801	Transposase and inactivated derivatives
BO993_08205	COG3039	Transposase
BO993_08220	COG1752	Esterase of the alpha-beta hydrolase superfamily
BO993_08230	COG1119	ATPase activity
BO993_08245	COG1125	glycine betaine transport
BO993_08245	COG0517	IMP dehydrogenase activity
BO993_08260	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BO993_08265	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
BO993_08270	COG3550	peptidyl-serine autophosphorylation
BO993_08275	COG1396	sequence-specific DNA binding
BO993_08295	COG0489	protein tyrosine kinase activity
BO993_08300	COG2062	phosphohistidine phosphatase, SixA
BO993_08310	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BO993_08360	COG0174	glutamine synthetase
BO993_08365	COG0347	Belongs to the P(II) protein family
BO993_08370	COG0004	ammonium transporteR
BO993_08375	COG3852	Histidine kinase
BO993_08380	COG2204	response regulator
BO993_08385	COG2032	superoxide dismutase activity
BO993_08390	COG2032	superoxide dismutase activity
BO993_08430	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BO993_08435	COG1074	ATP-dependent DNA helicase activity
BO993_08445	COG3549	Plasmid maintenance system killer
BO993_08520	COG1764	response to oxidative stress
BO993_08525	COG1846	Transcriptional regulator
BO993_08585	COG3293	Transposase
BO993_08620	COG2211	Major facilitator Superfamily
BO993_08640	COG3693	PFAM glycoside hydrolase, family 10
BO993_08645	COG3693	PFAM glycoside hydrolase, family 10
BO993_08670	COG0246	Mannitol dehydrogenase
BO993_08675	COG1472	Belongs to the glycosyl hydrolase 3 family
BO993_08685	COG4948	Mandelate Racemase Muconate Lactonizing
BO993_08695	COG3661	Belongs to the glycosyl hydrolase 67 family
BO993_08710	COG0037	tRNA processing
BO993_08715	COG2974	May be involved in recombination
BO993_08740	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BO993_08750	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BO993_08760	COG0805	protein transport
BO993_08770	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BO993_08770	COG0519	Catalyzes the synthesis of GMP from XMP
BO993_08790	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BO993_08795	COG0752	glycyl-tRNA synthetase alpha subunit
BO993_08805	COG0457	Tetratricopeptide repeat
BO993_08810	COG4771	TonB-dependent receptor
BO993_08825	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BO993_08835	COG0697	spore germination
BO993_08845	COG0523	cobalamin synthesis protein
BO993_08905	COG1960	acyl-CoA dehydrogenase activity
BO993_08910	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BO993_08950	COG2801	Transposase and inactivated derivatives
BO993_08975	COG2351	hydroxyisourate hydrolase activity
BO993_08995	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BO993_09040	COG0084	hydrolase, TatD family'
BO993_09055	COG0583	DNA-binding transcription factor activity
BO993_09060	COG2814	Major facilitator Superfamily
BO993_09070	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BO993_09075	COG1902	pentaerythritol trinitrate reductase activity
BO993_09105	COG0745	RESPONSE REGULATOR receiver
BO993_09110	COG2205	protein histidine kinase activity
BO993_09115	COG2205	protein histidine kinase activity
BO993_09130	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BO993_09135	COG0583	DNA-binding transcription factor activity
BO993_09165	COG0702	epimerase
BO993_09170	COG1733	regulation of RNA biosynthetic process
BO993_09230	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BO993_09245	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BO993_09285	COG2911	Protein conserved in bacteria
BO993_09290	COG0729	surface antigen
BO993_09310	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BO993_09315	COG3118	belongs to the thioredoxin family
BO993_09325	COG2884	Cell division ATP-binding protein ftsE
BO993_09330	COG2177	Part of the ABC transporter FtsEX involved in
BO993_09335	COG2201	protein-glutamate methylesterase activity
BO993_09345	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BO993_09355	COG1252	NADH dehydrogenase
BO993_09380	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BO993_09395	COG4771	TonB-dependent receptor
BO993_09410	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BO993_09450	COG3386	PFAM SMP-30 Gluconolaconase
BO993_09465	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BO993_09470	COG3293	Transposase
BO993_09515	COG0778	Nitroreductase
BO993_09520	COG2353	YceI-like domain
BO993_09605	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BO993_09660	COG3039	Transposase
BO993_09690	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BO993_09745	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BO993_09750	COG0318	PFAM AMP-dependent synthetase and ligase
BO993_09760	COG0596	Alpha beta hydrolase
BO993_09775	COG3177	Filamentation induced by cAMP protein fic
BO993_09780	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BO993_09795	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BO993_09820	COG4191	Histidine kinase
BO993_09825	COG0028	Belongs to the TPP enzyme family
BO993_09845	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BO993_09875	COG5383	Protein conserved in bacteria
BO993_09885	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BO993_09890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BO993_09895	COG1473	amidohydrolase
BO993_09925	COG3039	Transposase
BO993_09940	COG3039	Transposase
BO993_09980	COG2801	Transposase and inactivated derivatives
BO993_10015	COG0134	indole-3-glycerol-phosphate synthase activity
BO993_10105	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BO993_10115	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
BO993_10180	COG0358	DNA primase activity
BO993_10185	COG1295	ribonuclease BN
BO993_10195	COG1610	YqeY-like protein
BO993_10200	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BO993_10210	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BO993_10250	COG2133	pyrroloquinoline quinone binding
BO993_10255	COG4682	membrane
BO993_10275	COG3293	Transposase
BO993_10285	COG0531	amino acid
BO993_10295	COG3293	Transposase
BO993_10325	COG4948	Mandelate Racemase Muconate Lactonizing
BO993_10335	COG3023	N-Acetylmuramoyl-L-alanine amidase
BO993_10340	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
BO993_10410	COG0183	Belongs to the thiolase family
BO993_10420	COG3293	Transposase
BO993_10465	COG3104	oligopeptide transport
BO993_10495	COG1320	monovalent cation:proton antiporter activity
BO993_10500	COG2212	antiporter activity
BO993_10510	COG0651	ATP synthesis coupled electron transport
BO993_10515	COG1006	Multisubunit Na H antiporter MnhC subunit
BO993_10520	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BO993_10520	COG2111	Na H antiporter
BO993_10535	COG3227	Zinc metalloprotease (Elastase)
BO993_10570	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BO993_10580	COG0456	acetyltransferase
BO993_10615	COG4221	oxidoreductase activity
BO993_10680	COG0697	spore germination
BO993_10685	COG4305	rare lipoprotein A
BO993_10690	COG5297	Belongs to the glycosyl hydrolase family 6
BO993_10695	COG1113	amino acid transport
BO993_10705	COG0598	Magnesium transport protein CorA
BO993_10745	COG3293	Transposase
BO993_10785	COG0840	transmembrane signaling receptor activity
BO993_10795	COG5297	Belongs to the glycosyl hydrolase family 6
BO993_10795	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BO993_10800	COG0659	secondary active sulfate transmembrane transporter activity
BO993_10810	COG3706	GGDEF domain
BO993_10825	COG3293	Transposase
BO993_10845	COG3275	phosphorelay sensor kinase activity
BO993_10880	COG1505	serine-type exopeptidase activity
BO993_10895	COG3293	Transposase
BO993_10905	COG3039	Transposase
BO993_10940	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BO993_10970	COG0308	aminopeptidase N
BO993_10975	COG2199	diguanylate cyclase activity
BO993_11040	COG1077	Cell shape determining protein MreB Mrl
BO993_11045	COG1792	Involved in formation and maintenance of cell shape
BO993_11060	COG0772	Belongs to the SEDS family
BO993_11085	COG3501	Rhs element vgr protein
BO993_11120	COG2951	lytic endotransglycosylase activity
BO993_11125	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BO993_11135	COG1686	Belongs to the peptidase S11 family
BO993_11170	COG1051	belongs to the nudix hydrolase family
BO993_11170	COG1056	cytidyltransferase-related domain
BO993_11210	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BO993_11215	COG0673	inositol 2-dehydrogenase activity
BO993_11220	COG2823	Periplasmic or secreted lipoprotein
BO993_11225	COG4251	negative regulation of phosphorylation
BO993_11230	COG0784	Response regulator, receiver
BO993_11235	COG4191	Histidine kinase
BO993_11240	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BO993_11260	COG2801	Transposase and inactivated derivatives
BO993_11270	COG2963	transposase activity
BO993_11280	COG3250	beta-galactosidase activity
BO993_11305	COG1609	Transcriptional regulator
BO993_11310	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BO993_11315	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BO993_11325	COG1215	transferase activity, transferring glycosyl groups
BO993_11330	COG1649	PFAM Uncharacterised BCR, COG1649
BO993_11330	COG0726	polysaccharide deacetylase
BO993_11410	COG3039	Transposase
BO993_11435	COG3039	Transposase
BO993_11445	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BO993_11525	COG2205	protein histidine kinase activity
BO993_11530	COG0745	RESPONSE REGULATOR receiver
BO993_11575	COG3039	Transposase
BO993_11585	COG0488	(ABC) transporter
BO993_11625	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BO993_11625	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BO993_11655	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BO993_11680	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BO993_11685	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BO993_11695	COG2205	protein histidine kinase activity
BO993_11700	COG0745	RESPONSE REGULATOR receiver
BO993_11705	COG0277	FAD linked oxidase domain protein
BO993_11710	COG1988	membrane-bound metal-dependent
BO993_11755	COG3116	cell division
BO993_11770	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BO993_11775	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BO993_11795	COG1181	Belongs to the D-alanine--D-alanine ligase family
BO993_11800	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BO993_11825	COG1388	LysM domain
BO993_11825	COG4942	peptidase
BO993_11840	COG0494	nUDIX hydrolase
BO993_11855	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BO993_11865	COG0604	alcohol dehydrogenase
BO993_11865	COG1028	Short-chain dehydrogenase reductase Sdr
BO993_11865	COG3321	synthase
BO993_11920	COG2226	methyltransferase
BO993_11975	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BO993_11985	COG4106	trans-aconitate 2-methyltransferase activity
BO993_11990	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BO993_12005	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BO993_12010	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BO993_12020	COG3039	Transposase
BO993_12030	COG0667	Aldo Keto reductase
BO993_12045	COG3293	Transposase
BO993_12090	COG2175	clavaminate synthase activity
BO993_12100	COG4181	ATPase activity
BO993_12115	COG0642	Histidine kinase
BO993_12140	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BO993_12205	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BO993_12220	COG0123	including yeast histone deacetylase and acetoin utilization protein
BO993_12225	COG2096	Adenosyltransferase
BO993_12235	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BO993_12240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BO993_12280	COG0583	DNA-binding transcription factor activity
BO993_12285	COG0318	PFAM AMP-dependent synthetase and ligase
BO993_12295	COG1024	Enoyl-CoA hydratase
BO993_12315	COG3386	PFAM SMP-30 Gluconolaconase
BO993_12395	COG0745	RESPONSE REGULATOR receiver
BO993_12395	COG3706	GGDEF domain
BO993_12440	COG1902	pentaerythritol trinitrate reductase activity
BO993_12440	COG0446	pyridine nucleotide-disulphide oxidoreductase
BO993_12470	COG0156	8-amino-7-oxononanoate synthase activity
BO993_12475	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BO993_12480	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BO993_12485	COG4208	sulfate ABC transporter
BO993_12490	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BO993_12520	COG0588	phosphoglycerate mutase activity
BO993_12530	COG0285	dihydrofolate synthase activity
BO993_12550	COG2833	Protein of unknown function (DUF455)
BO993_12570	COG0671	phosphoesterase, PA-phosphatase related
BO993_12575	COG0438	transferase activity, transferring glycosyl groups
BO993_12585	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BO993_12600	COG4783	chaperone-mediated protein folding
BO993_12630	COG0473	3-isopropylmalate dehydrogenase activity
BO993_12685	COG0544	peptidyl-prolyl cis-trans isomerase activity
BO993_12690	COG0740	serine-type endopeptidase activity
BO993_12725	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BO993_12750	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BO993_12760	COG0631	protein serine/threonine phosphatase activity
BO993_12810	COG0582	viral genome integration into host DNA
BO993_12820	COG0859	PFAM glycosyl transferase family 9
BO993_12830	COG1234	tRNA 3'-trailer cleavage
BO993_12835	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BO993_12850	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BO993_12855	COG0314	molybdopterin synthase activity
BO993_12885	COG0537	adenosine 5'-monophosphoramidase activity
BO993_12905	COG0714	Associated with various cellular activities
BO993_12925	COG0242	peptide deformylase activity
BO993_12970	COG3039	Transposase
BO993_12995	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BO993_13000	COG0726	polysaccharide deacetylase
BO993_13025	COG1162	GTPase activity
BO993_13050	COG2211	Major facilitator Superfamily
BO993_13060	COG1609	Transcriptional regulator
BO993_13065	COG1028	Short-chain dehydrogenase reductase Sdr
BO993_13070	COG2851	Citrate transporter
BO993_13085	COG0642	Histidine kinase
BO993_13090	COG1840	ABC-type Fe3 transport system, periplasmic component
BO993_13095	COG2197	response regulator
BO993_13120	COG0583	DNA-binding transcription factor activity
BO993_13135	COG4191	Histidine kinase
BO993_13155	COG0281	malic enzyme
BO993_13155	COG0280	phosphate acetyltransferase
BO993_13230	COG0352	thiamine-phosphate diphosphorylase activity
BO993_13235	COG1773	rubredoxin
BO993_13240	COG2912	Transglutaminase-like superfamily
BO993_13250	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BO993_13260	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BO993_13285	COG0006	proline dipeptidase activity
BO993_13315	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BO993_13335	COG1561	YicC-like family, N-terminal region
BO993_13360	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BO993_13370	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BO993_13380	COG0254	rRNA binding
BO993_13395	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BO993_13435	COG0714	Associated with various cellular activities
BO993_13455	COG2304	oxidoreductase activity
BO993_13475	COG1301	dicarboxylic acid transport
BO993_13480	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BO993_13485	COG4773	Receptor
BO993_13490	COG0739	heme binding
BO993_13495	COG1376	ErfK ybiS ycfS ynhG family protein
BO993_13520	COG1022	Amp-dependent synthetase and ligase
BO993_13530	COG1028	Short-chain dehydrogenase reductase Sdr
BO993_13540	COG0745	RESPONSE REGULATOR receiver
BO993_13545	COG0642	Histidine kinase
BO993_13565	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BO993_13570	COG4149	molybdate abc transporter
BO993_13575	COG0725	ABC transporter, periplasmic molybdate-binding protein
BO993_13580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BO993_13580	COG3453	Protein conserved in bacteria
BO993_13615	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BO993_13620	COG3293	Transposase
BO993_13635	COG2205	protein histidine kinase activity
BO993_13640	COG0745	RESPONSE REGULATOR receiver
BO993_13655	COG3039	Transposase
BO993_13690	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BO993_13695	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BO993_13730	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BO993_13750	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BO993_13840	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BO993_13850	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BO993_13870	COG1842	Phage shock protein A
BO993_13895	COG0754	glutathionylspermidine amidase activity
BO993_13905	COG0789	Transcriptional regulator
BO993_13960	COG0531	amino acid
BO993_13965	COG2197	response regulator
BO993_13980	COG1113	amino acid transport
BO993_13990	COG1271	oxidase subunit
BO993_13995	COG1294	oxidase, subunit
BO993_14005	COG2239	Acts as a magnesium transporter
BO993_14010	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BO993_14015	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BO993_14035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BO993_14050	COG1137	ATPase activity
BO993_14055	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BO993_14065	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BO993_14075	COG0271	Belongs to the BolA IbaG family
BO993_14100	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BO993_14125	COG0628	permease
BO993_14135	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BO993_14140	COG3178	'Phosphotransferase
BO993_14160	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BO993_14165	COG1555	photosystem II stabilization
BO993_14210	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BO993_14220	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BO993_14270	COG0534	Mate efflux family protein
BO993_14310	COG0542	response to heat
BO993_14325	COG2963	transposase activity
BO993_14340	COG4206	TonB-dependent receptor
BO993_14400	COG0019	diaminopimelate decarboxylase activity
BO993_14410	COG2814	Major facilitator Superfamily
BO993_14415	COG4264	IucA IucC family
BO993_14425	COG4772	TonB-dependent receptor
BO993_14440	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BO993_14440	COG4651	solute:proton antiporter activity
BO993_14480	COG0488	(ABC) transporter
BO993_14505	COG0657	acetylesterase activity
BO993_14505	COG2755	lipolytic protein G-D-S-L family
BO993_14535	COG2207	Transcriptional regulator
BO993_14540	COG0326	Molecular chaperone. Has ATPase activity
BO993_14590	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BO993_14595	COG2801	Transposase and inactivated derivatives
BO993_14605	COG3039	Transposase
BO993_14620	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BO993_14625	COG0719	Fe-S assembly protein
BO993_14630	COG0396	ATPase activity
BO993_14635	COG0719	Fe-S assembly protein
BO993_14640	COG1959	2 iron, 2 sulfur cluster binding
BO993_14700	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BO993_14730	COG0519	Catalyzes the synthesis of GMP from XMP
BO993_14765	COG1764	response to oxidative stress
BO993_14775	COG0384	phenazine biosynthesis protein PhzF
BO993_14780	COG0384	phenazine biosynthesis protein PhzF
BO993_14790	COG0527	aspartate kinase activity
BO993_14820	COG0142	geranyltranstransferase activity
BO993_14825	COG0629	single-stranded DNA binding
BO993_14835	COG5001	Diguanylate cyclase
BO993_14835	COG4251	negative regulation of phosphorylation
BO993_14835	COG2203	Gaf domain
BO993_14835	COG3706	GGDEF domain
BO993_14850	COG0604	alcohol dehydrogenase
BO993_14850	COG1028	Short-chain dehydrogenase reductase Sdr
BO993_14850	COG3321	synthase
BO993_14885	COG2879	small protein
BO993_14890	COG1966	Carbon starvation protein
BO993_14895	COG1741	Belongs to the pirin family
BO993_14950	COG1741	Belongs to the pirin family
BO993_14960	COG1515	deoxyribonuclease V activity
BO993_14965	COG0588	phosphoglycerate mutase activity
BO993_14985	COG3590	peptidase
BO993_15000	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BO993_15005	COG2202	Pas domain
BO993_15005	COG2200	EAL domain
BO993_15005	COG2199	diguanylate cyclase activity
BO993_15010	COG0835	chemotaxis
BO993_15015	COG0840	transmembrane signaling receptor activity
BO993_15020	COG0643	Histidine kinase
BO993_15020	COG2198	Histidine kinase
BO993_15030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BO993_15040	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BO993_15055	COG2205	protein histidine kinase activity
BO993_15095	COG3039	Transposase
BO993_15135	COG0735	belongs to the Fur family
BO993_15180	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BO993_15185	COG0084	hydrolase, TatD family'
BO993_15200	COG1960	acyl-CoA dehydrogenase activity
BO993_15225	COG0367	asparagine synthase
BO993_15235	COG0305	Participates in initiation and elongation during chromosome replication
BO993_15240	COG0415	Belongs to the DNA photolyase family
BO993_15260	COG1028	Short-chain dehydrogenase reductase Sdr
BO993_15375	COG5001	Diguanylate cyclase
BO993_15375	COG5002	protein histidine kinase activity
BO993_15380	COG1187	pseudouridine synthase activity
BO993_15410	COG0475	glutathione-regulated potassium exporter activity
BO993_15415	COG5000	phosphorelay sensor kinase activity
BO993_15415	COG5002	protein histidine kinase activity
BO993_15420	COG0745	RESPONSE REGULATOR receiver
BO993_15450	COG1132	(ABC) transporter
BO993_15460	COG3293	Transposase
BO993_15475	COG3039	Transposase
BO993_15480	COG3039	Transposase
BO993_15495	COG3039	Transposase
BO993_15515	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BO993_15525	COG4969	Belongs to the N-Me-Phe pilin family
BO993_15530	COG2194	sulfuric ester hydrolase activity
BO993_15550	COG2184	nucleotidyltransferase activity
BO993_15575	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BO993_15585	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BO993_15585	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BO993_15590	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BO993_15595	COG0564	pseudouridine synthase activity
BO993_15620	COG3387	PFAM Glycoside hydrolase 15-related
BO993_15625	COG1877	trehalose-phosphatase activity
BO993_15680	COG1595	DNA-templated transcription, initiation
BO993_15690	COG1946	Acyl-CoA thioesterase
BO993_15705	COG0824	Thioesterase
BO993_15710	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BO993_15730	COG0268	Binds directly to 16S ribosomal RNA
BO993_15735	COG0728	peptidoglycan biosynthetic process
BO993_15740	COG0196	riboflavin kinase activity
BO993_15770	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BO993_15775	COG1845	cytochrome c oxidase, subunit III
BO993_15780	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BO993_15790	COG3501	Rhs element vgr protein
BO993_15855	COG2963	transposase activity
BO993_15860	COG2801	Transposase and inactivated derivatives
BO993_15885	COG2801	Transposase and inactivated derivatives
BO993_15890	COG2963	transposase activity
BO993_15990	COG0824	Thioesterase
BO993_16000	COG0848	biopolymer transport protein
BO993_16015	COG2885	chlorophyll binding
BO993_16025	COG0602	queuosine metabolic process
BO993_16030	COG1187	pseudouridine synthase activity
BO993_16080	COG3293	Transposase
BO993_16115	COG0514	ATP-dependent DNA helicase (RecQ)
BO993_16120	COG0783	Belongs to the Dps family
BO993_16125	COG1643	Atp-dependent helicase
BO993_16135	COG0837	glucose binding
BO993_16140	COG0837	glucose binding
BO993_16145	COG0837	glucose binding
BO993_16160	COG0535	radical SAM domain protein
BO993_16165	COG0535	radical SAM domain protein
BO993_16180	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BO993_16195	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BO993_16205	COG1199	ATP-dependent helicase activity
BO993_16215	COG1397	ADP-ribosylglycohydrolase
BO993_16225	COG0189	ligase activity
BO993_16240	COG0835	chemotaxis
BO993_16245	COG0840	transmembrane signaling receptor activity
BO993_16270	COG3039	Transposase
BO993_16290	COG2304	oxidoreductase activity
BO993_16305	COG1446	asparaginase
BO993_16310	COG3142	Participates in the control of copper homeostasis
BO993_16355	COG3537	Alpha-1,2-mannosidase
BO993_16400	COG1472	Belongs to the glycosyl hydrolase 3 family
BO993_16410	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BO993_16420	COG3858	chitin binding
BO993_16420	COG1388	LysM domain
BO993_16435	COG0837	glucose binding
BO993_16440	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BO993_16450	COG0494	nUDIX hydrolase
BO993_16460	COG3956	TIGRFAM MazG family protein
BO993_16475	COG0330	HflC and HflK could
BO993_16515	COG1960	acyl-CoA dehydrogenase activity
BO993_16525	COG1309	transcriptional regulator
BO993_16530	COG4771	TonB-dependent receptor
BO993_16540	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BO993_16550	COG0463	Glycosyl transferase, family 2
BO993_16555	COG0516	GMP reductase activity
BO993_16555	COG0517	IMP dehydrogenase activity
BO993_16565	COG1272	protein, Hemolysin III
BO993_16575	COG0739	heme binding
BO993_16580	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BO993_16585	COG0626	cystathionine gamma-synthase activity
BO993_16595	COG1760	l-serine dehydratase
BO993_16605	COG2353	YceI-like domain
BO993_16615	COG2353	YceI-like domain
BO993_16650	COG2963	transposase activity
BO993_16695	COG1960	acyl-CoA dehydrogenase activity
BO993_16700	COG1024	Enoyl-CoA hydratase
BO993_16720	COG1250	3-hydroxyacyl-CoA dehydrogenase
BO993_16720	COG1024	Enoyl-CoA hydratase
BO993_16735	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BO993_16790	COG3039	Transposase
BO993_16815	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BO993_16825	COG3046	protein related to deoxyribodipyrimidine photolyase
BO993_16840	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BO993_16845	COG1278	Cold shock
BO993_16870	COG1201	RNA secondary structure unwinding
BO993_16875	COG1793	dna ligase
BO993_16885	COG1793	dna ligase
BO993_16885	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BO993_16900	COG0745	RESPONSE REGULATOR receiver
BO993_16900	COG3706	GGDEF domain
BO993_16915	COG0183	Belongs to the thiolase family
BO993_16935	COG1451	nucleotide metabolic process
BO993_16950	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BO993_17000	COG1047	Peptidyl-prolyl cis-trans
BO993_17015	COG2824	Alkylphosphonate utilization operon protein PhnA
BO993_17025	COG1902	pentaerythritol trinitrate reductase activity
BO993_17030	COG2814	Major facilitator Superfamily
BO993_17040	COG3039	Transposase
BO993_17070	COG0392	lysyltransferase activity
BO993_17070	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BO993_17080	COG0251	oxidation-reduction process
BO993_17085	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BO993_17100	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BO993_17125	COG1595	DNA-templated transcription, initiation
BO993_17145	COG2878	Part of a membrane complex involved in electron transport
BO993_17175	COG0833	amino acid
BO993_17180	COG2040	homocysteine
BO993_17195	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BO993_17315	COG1131	(ABC) transporter
BO993_17320	COG4771	TonB-dependent receptor
BO993_17370	COG0750	zinc metalloprotease
BO993_17380	COG0575	Belongs to the CDS family
BO993_17445	COG0024	Methionine aminopeptidase
BO993_17455	COG3039	Transposase
BO993_17470	COG1393	Belongs to the ArsC family
BO993_17485	COG0367	asparagine synthase
BO993_17500	COG4774	siderophore transport
BO993_17530	COG2207	Transcriptional regulator
BO993_17545	COG1566	PFAM secretion protein HlyD family protein
BO993_17550	COG2814	Major facilitator Superfamily
BO993_17620	COG1960	acyl-CoA dehydrogenase activity
BO993_17640	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BO993_17650	COG2914	Belongs to the UPF0125 (RnfH) family
BO993_17655	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BO993_17665	COG0497	DNA recombination
BO993_17690	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BO993_17695	COG1605	Chorismate mutase
BO993_17695	COG0287	Prephenate dehydrogenase
BO993_17710	COG0583	DNA-binding transcription factor activity
BO993_17720	COG1132	(ABC) transporter
BO993_17755	COG2850	peptidyl-arginine hydroxylation
BO993_17820	COG1131	(ABC) transporter
BO993_17825	COG1725	Transcriptional regulator
BO993_17835	COG0386	Belongs to the glutathione peroxidase family
BO993_17875	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BO993_17885	COG0646	methionine synthase
BO993_17885	COG1410	methionine synthase
BO993_17890	COG1410	methionine synthase
BO993_17890	COG0646	methionine synthase
BO993_17900	COG1960	acyl-CoA dehydrogenase activity
BO993_17925	COG0557	exoribonuclease II activity
BO993_17950	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BO993_17960	COG3039	Transposase
BO993_18025	COG2801	Transposase and inactivated derivatives
BO993_18080	COG0583	DNA-binding transcription factor activity
BO993_18100	COG2201	protein-glutamate methylesterase activity
BO993_18170	COG0235	Class ii aldolase
BO993_18175	COG0531	amino acid
BO993_18180	COG0531	amino acid
BO993_18190	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BO993_18195	COG0277	FAD linked oxidase domain protein
BO993_18255	COG0436	Aminotransferase
BO993_18280	COG1187	pseudouridine synthase activity
BO993_18285	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BO993_18290	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BO993_18295	COG2350	Protein conserved in bacteria
BO993_18325	COG1175	transmembrane transport
BO993_18330	COG0395	ABC-type sugar transport system, permease component
BO993_18355	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BO993_18365	COG2957	Belongs to the agmatine deiminase family
BO993_18375	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BO993_18385	COG0539	negative regulation of cytoplasmic translation
BO993_18400	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BO993_18405	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BO993_18415	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BO993_18420	COG0475	glutathione-regulated potassium exporter activity
BO993_18420	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BO993_18470	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BO993_18475	COG0583	DNA-binding transcription factor activity
BO993_18505	COG0583	DNA-binding transcription factor activity
BO993_18510	COG0583	DNA-binding transcription factor activity
BO993_18525	COG1914	H( )-stimulated, divalent metal cation uptake system
BO993_18530	COG1321	iron dependent repressor
BO993_18535	COG0590	tRNA wobble adenosine to inosine editing
BO993_18545	COG0668	transmembrane transport
BO993_18570	COG1028	Short-chain dehydrogenase reductase Sdr
BO993_18575	COG1183	phosphatidylcholine synthase activity
BO993_18585	COG3243	poly(R)-hydroxyalkanoic acid synthase
BO993_18600	COG0723	plastoquinol--plastocyanin reductase activity
BO993_18600	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BO993_18610	COG2183	response to ionizing radiation
BO993_18625	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BO993_18640	COG0671	phosphoesterase, PA-phosphatase related
BO993_18660	COG1794	racemase activity, acting on amino acids and derivatives
BO993_18665	COG0697	spore germination
BO993_18690	COG1012	belongs to the aldehyde dehydrogenase family
BO993_18725	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BO993_18740	COG0124	histidyl-tRNA synthetase
BO993_18800	COG0140	phosphoribosyl-ATP diphosphatase activity
BO993_18800	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BO993_18955	COG3293	Transposase
BO993_19005	COG3039	Transposase
BO993_19065	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BO993_19090	COG0811	peptide transport
BO993_19115	COG4591	ABC-type transport system involved in lipoprotein release permease component
BO993_19130	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BO993_19145	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BO993_19155	COG0354	folic acid binding
BO993_19170	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BO993_19180	COG0363	glucosamine-6-phosphate deaminase activity
BO993_19185	COG0129	dihydroxy-acid dehydratase activity
BO993_19190	COG0800	Aldolase
BO993_19210	COG3293	Transposase
BO993_19235	COG5002	protein histidine kinase activity
BO993_19235	COG2205	protein histidine kinase activity
BO993_19235	COG0784	Response regulator, receiver
BO993_19250	COG3039	Transposase
BO993_19275	COG3706	GGDEF domain
BO993_19330	COG0386	Belongs to the glutathione peroxidase family
BO993_19355	COG1595	DNA-templated transcription, initiation
BO993_19415	COG3706	GGDEF domain
BO993_19415	COG2203	Gaf domain
BO993_19415	COG4251	negative regulation of phosphorylation
BO993_19415	COG5001	Diguanylate cyclase
BO993_19430	COG1472	Belongs to the glycosyl hydrolase 3 family
BO993_19460	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BO993_19465	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BO993_19475	COG0617	tRNA 3'-terminal CCA addition
BO993_19490	COG0860	N-Acetylmuramoyl-L-alanine amidase
BO993_19540	COG4566	intracellular signal transduction
BO993_19550	COG2963	transposase activity
BO993_19565	COG1605	Chorismate mutase
BO993_19565	COG0077	Prephenate dehydratase
BO993_19575	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BO993_19625	COG2986	histidine ammonia-lyase
BO993_19635	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BO993_19655	COG2963	transposase activity
BO993_19690	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
BO993_19705	COG3115	cell septum assembly
BO993_19730	COG0316	Belongs to the HesB IscA family
BO993_19765	COG0288	reversible hydration of carbon dioxide
BO993_19790	COG2925	Exonuclease
BO993_19800	COG0667	Aldo Keto reductase
BO993_19835	COG0488	(ABC) transporter
BO993_19840	COG4133	protoheme IX ABC transporter activity
BO993_19845	COG0488	(ABC) transporter
BO993_19880	COG0494	nUDIX hydrolase
BO993_19890	COG1024	Enoyl-CoA hydratase
BO993_19900	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BO993_19925	COG3293	Transposase
BO993_19945	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BO993_19950	COG0573	inorganic phosphate transmembrane transporter activity
BO993_19965	COG0704	Plays a role in the regulation of phosphate uptake
BO993_19975	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BO993_20015	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BO993_20025	COG1862	Preprotein translocase
BO993_20125	COG3039	Transposase
BO993_20135	COG3293	Transposase
BO993_20150	COG0405	Gamma-glutamyltransferase
BO993_20155	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BO993_20175	COG0742	ribosomal rna small subunit methyltransferase
BO993_20220	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BO993_20255	COG2826	transposase and inactivated derivatives, IS30 family
BO993_20290	COG0303	'Molybdopterin
BO993_20300	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BO993_20310	COG1426	Protein conserved in bacteria
BO993_20325	COG0105	UTP biosynthetic process
BO993_20335	COG1250	3-hydroxyacyl-CoA dehydrogenase
BO993_20335	COG1024	Enoyl-CoA hydratase
BO993_20340	COG0183	Belongs to the thiolase family
BO993_20345	COG0038	chloride channel
BO993_20365	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BO993_20385	COG1674	ftsk spoiiie
BO993_20390	COG0492	ferredoxin-NADP+ reductase activity
BO993_20415	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BO993_20420	COG0542	response to heat
BO993_20425	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BO993_20435	COG0482	sulfurtransferase activity
BO993_20460	COG5001	Diguanylate cyclase
BO993_20465	COG4585	Histidine kinase
BO993_20475	COG5002	protein histidine kinase activity
BO993_20495	COG0784	Response regulator, receiver
BO993_20495	COG0835	chemotaxis
BO993_20505	COG1558	bacterial-type flagellum-dependent cell motility
BO993_20510	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BO993_20515	COG1749	Flagellar hook protein flgE
BO993_20520	COG4787	bacterial-type flagellum-dependent cell motility
BO993_20525	COG4786	Flagellar basal body rod
BO993_20540	COG3951	Flagellar rod assembly protein muramidase FlgJ
BO993_20540	COG1705	Flagellar rod assembly protein muramidase FlgJ
BO993_20555	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BO993_20560	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BO993_20590	COG2201	protein-glutamate methylesterase activity
BO993_20595	COG2204	response regulator
BO993_20610	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BO993_20620	COG1028	Short-chain dehydrogenase reductase Sdr
BO993_20650	COG1677	Flagellar hook-basal body complex protein FliE
BO993_20700	COG3190	flagellar
BO993_20710	COG1987	bacterial-type flagellum assembly
BO993_20715	COG1684	flagellar biosynthetic protein fliR
BO993_20720	COG5001	Diguanylate cyclase
BO993_20720	COG3300	MHYT domain
BO993_20725	COG5001	Diguanylate cyclase
BO993_20725	COG3300	MHYT domain
BO993_20740	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BO993_20750	COG0455	bacterial-type flagellum organization
BO993_20770	COG0643	Histidine kinase
BO993_20770	COG2198	Histidine kinase
BO993_20810	COG3293	Transposase
BO993_20815	COG3039	Transposase
BO993_20820	COG3209	COG3209 Rhs family protein
BO993_20840	COG3039	Transposase
BO993_20880	COG3293	Transposase
BO993_20955	COG3039	Transposase
BO993_20960	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BO993_20965	COG4988	ABC transporter
BO993_20970	COG1271	oxidase subunit
BO993_20985	COG1271	oxidase subunit
BO993_20990	COG1294	oxidase, subunit
BO993_21050	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BO993_21055	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BO993_21065	COG0137	argininosuccinate synthase activity
BO993_21070	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BO993_21085	COG2166	iron-sulfur cluster assembly
BO993_21100	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BO993_21115	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BO993_21125	COG4302	ethanolamine ammonia-lyase activity
BO993_21140	COG4677	pectinesterase activity
BO993_21175	COG0402	S-adenosylhomocysteine deaminase activity
BO993_21190	COG1509	lysine 2,3-aminomutase activity
BO993_21195	COG3300	MHYT domain
BO993_21195	COG5001	Diguanylate cyclase
BO993_21210	COG0483	inositol monophosphate 1-phosphatase activity
BO993_21245	COG0513	Belongs to the DEAD box helicase family
BO993_21250	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BO993_21255	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BO993_21265	COG0625	glutathione transferase activity
BO993_21280	COG4681	YaeQ
BO993_21285	COG2081	HI0933 family
BO993_21295	COG0501	Belongs to the peptidase M48B family
BO993_21305	COG1028	Short-chain dehydrogenase reductase Sdr
BO993_21330	COG0860	N-Acetylmuramoyl-L-alanine amidase
BO993_21335	COG0802	atpase or kinase
BO993_21340	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BO993_21340	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BO993_21345	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BO993_21365	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BO993_21420	COG3328	transposase activity
BO993_21455	COG2969	positive regulation of protein catabolic process
BO993_21460	COG0625	glutathione transferase activity
BO993_21465	COG2857	Cytochrome c1
BO993_21470	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BO993_21475	COG0723	plastoquinol--plastocyanin reductase activity
BO993_21480	COG0741	lytic transglycosylase activity
BO993_21510	COG1702	phosphate starvation-inducible protein PhoH
BO993_21530	COG4535	Mg2 and Co2 transporter CorC
BO993_21545	COG1012	belongs to the aldehyde dehydrogenase family
BO993_21555	COG1177	transmembrane transport
BO993_21595	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BO993_21600	COG0174	glutamine synthetase
BO993_21605	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BO993_21610	COG0745	RESPONSE REGULATOR receiver
BO993_21610	COG3706	GGDEF domain
BO993_21615	COG0477	Major facilitator Superfamily
BO993_21625	COG0243	molybdopterin cofactor binding
BO993_21650	COG1121	(ABC) transporter
BO993_21660	COG2733	membrane
BO993_21675	COG3039	Transposase
BO993_21680	COG3039	Transposase
BO993_21685	COG2902	Dehydrogenase
BO993_21695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BO993_21700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BO993_21715	COG3293	Transposase
BO993_21730	COG1609	Transcriptional regulator
BO993_21735	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BO993_21735	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BO993_21740	COG1105	Belongs to the carbohydrate kinase PfkB family
BO993_21745	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BO993_21745	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BO993_21785	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BO993_21845	COG3501	Rhs element vgr protein
BO993_21860	COG2963	transposase activity
BO993_21880	COG2963	transposase activity
BO993_21885	COG3501	Rhs element vgr protein
BO993_21935	COG3039	Transposase
BO993_21975	COG4771	TonB-dependent receptor
BO993_21985	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BO993_22005	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BO993_22010	COG1360	Flagellar Motor Protein
BO993_22015	COG1192	Involved in chromosome partitioning
BO993_22020	COG0835	chemotaxis
BO993_22030	COG0745	RESPONSE REGULATOR receiver
BO993_22060	COG0840	transmembrane signaling receptor activity
BO993_22070	COG0840	transmembrane signaling receptor activity
BO993_22080	COG0840	transmembrane signaling receptor activity
BO993_22085	COG0840	transmembrane signaling receptor activity
BO993_22090	COG0840	transmembrane signaling receptor activity
BO993_22095	COG0840	transmembrane signaling receptor activity
BO993_22110	COG0835	chemotaxis
BO993_22120	COG3039	Transposase
BO993_22140	COG0840	transmembrane signaling receptor activity
BO993_22170	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BO993_22200	COG0318	PFAM AMP-dependent synthetase and ligase
BO993_22205	COG1024	Enoyl-CoA hydratase
BO993_22210	COG0784	Response regulator, receiver
BO993_22210	COG2198	Histidine kinase
BO993_22210	COG2205	protein histidine kinase activity
BO993_22230	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BO993_22265	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BO993_22275	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BO993_22280	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BO993_22290	COG0505	Belongs to the CarA family
BO993_22295	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BO993_22305	COG3293	Transposase
BO993_22310	COG2258	MOSC domain
BO993_22315	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BO993_22385	COG0477	Major facilitator Superfamily
BO993_22395	COG1070	Carbohydrate kinase
BO993_22410	COG1501	Belongs to the glycosyl hydrolase 31 family
BO993_22425	COG0800	Aldolase
BO993_22440	COG3734	2-keto-3-deoxy-galactonokinase
BO993_22445	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BO993_22455	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BO993_22475	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BO993_22480	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BO993_22490	COG0351	phosphomethylpyrimidine kinase
BO993_22520	COG0583	DNA-binding transcription factor activity
BO993_22525	COG1741	Belongs to the pirin family
BO993_22550	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BO993_22555	COG0305	Participates in initiation and elongation during chromosome replication
BO993_22575	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BO993_22585	COG2137	regulation of response to DNA damage stimulus
BO993_22605	COG1546	Belongs to the CinA family
BO993_22610	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BO993_22615	COG1923	regulation of RNA biosynthetic process
BO993_22625	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BO993_22630	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BO993_22640	COG1534	Rna-binding protein
BO993_22655	COG1238	metal cluster binding
BO993_22670	COG2840	Smr protein MutS2
BO993_22690	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BO993_22745	COG0306	phosphate transporter
BO993_22755	COG1253	flavin adenine dinucleotide binding
BO993_22770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BO993_22780	COG0477	Major facilitator Superfamily
BO993_22790	COG1132	(ABC) transporter
BO993_22795	COG1136	(ABC) transporter
BO993_22810	COG0438	transferase activity, transferring glycosyl groups
BO993_22820	COG2264	protein methyltransferase activity
BO993_22850	COG2244	polysaccharide biosynthetic process
BO993_22900	COG1595	DNA-templated transcription, initiation
BO993_22915	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BO993_22935	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BO993_22965	COG2201	protein-glutamate methylesterase activity
BO993_23005	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BO993_23010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BO993_23045	COG2963	transposase activity
BO993_23060	COG4644	lycopene metabolic process
BO993_23070	COG1858	cytochrome C peroxidase
BO993_23100	COG0515	serine threonine protein kinase
BO993_23105	COG0631	protein serine/threonine phosphatase activity
BO993_23140	COG3501	Rhs element vgr protein
BO993_23150	COG3039	Transposase
BO993_23215	COG3039	Transposase
BO993_23245	COG2801	Transposase and inactivated derivatives
BO993_23260	COG2154	pterin-4-alpha-carbinolamine dehydratase
BO993_23270	COG0428	transporter
BO993_23275	COG0428	transporter
BO993_23280	COG3064	Membrane
BO993_23290	COG1530	ribonuclease E activity
BO993_23300	COG3293	Transposase
BO993_23330	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BO993_23360	COG3293	Transposase
BO993_23425	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BO993_23425	COG1648	precorrin-2 dehydrogenase activity
BO993_23450	COG0746	molybdenum cofactor guanylyltransferase activity
BO993_23500	COG3328	transposase activity
BO993_23505	COG4206	TonB-dependent receptor
BO993_23525	COG4206	TonB-dependent receptor
BO993_23575	COG0531	amino acid
BO993_23590	COG0006	proline dipeptidase activity
BO993_23600	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BO993_23615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BO993_23620	COG3938	Belongs to the proline racemase family
BO993_23630	COG0552	protein localization to endoplasmic reticulum
BO993_23655	COG0784	Response regulator, receiver
BO993_23655	COG4191	Histidine kinase
BO993_23680	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BO993_23795	COG0438	transferase activity, transferring glycosyl groups
BO993_23800	COG0438	transferase activity, transferring glycosyl groups
BO993_23845	COG0776	regulation of translation
BO993_23855	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BO993_23860	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BO993_23865	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BO993_23870	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BO993_23885	COG2963	transposase activity
BO993_23910	COG0556	nucleotide-excision repair
BO993_23915	COG4969	Belongs to the N-Me-Phe pilin family
BO993_24055	COG4962	Type ii secretion system protein e
BO993_24070	COG3451	type IV secretory pathway VirB4
BO993_24145	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone