locus-tag	class	description
NO935_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NO935_00020	COG0187	DNA topoisomerase II activity
NO935_00030	COG0501	Belongs to the peptidase M48B family
NO935_00060	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
NO935_00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NO935_00080	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
NO935_00090	COG4772	TonB-dependent receptor
NO935_00105	COG3039	Transposase
NO935_00110	COG1304	FMN binding
NO935_00130	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NO935_00140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NO935_00235	COG2826	transposase and inactivated derivatives, IS30 family
NO935_00260	COG3039	Transposase
NO935_00270	COG1090	epimerase
NO935_00290	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NO935_00400	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NO935_00480	COG1511	domain protein
NO935_00480	COG3264	Mechanosensitive ion channel
NO935_00495	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NO935_00500	COG2354	Protein conserved in bacteria
NO935_00505	COG1649	PFAM Uncharacterised BCR, COG1649
NO935_00525	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NO935_00550	COG0702	epimerase
NO935_00565	COG1858	cytochrome C peroxidase
NO935_00635	COG0513	Belongs to the DEAD box helicase family
NO935_00640	COG3039	Transposase
NO935_00685	COG1136	(ABC) transporter
NO935_00710	COG3039	Transposase
NO935_00725	COG1136	(ABC) transporter
NO935_00765	COG1272	protein, Hemolysin III
NO935_00770	COG1205	dead DEAH box helicase
NO935_00770	COG1111	helicase
NO935_00830	COG0067	glutamate synthase
NO935_00830	COG0069	glutamate synthase activity
NO935_00830	COG0070	glutamate synthase
NO935_00835	COG0493	'glutamate synthase
NO935_00885	COG1609	Transcriptional regulator
NO935_00910	COG0366	Alpha amylase catalytic
NO935_00915	COG0366	Alpha amylase catalytic
NO935_00960	COG0606	chelatase, subunit chli
NO935_01005	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NO935_01010	COG1166	arginine decarboxylase activity
NO935_01075	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NO935_01100	COG1028	Short-chain dehydrogenase reductase Sdr
NO935_01125	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
NO935_01140	COG0210	DNA helicase
NO935_01155	COG3132	Protein of unknown function, DUF480
NO935_01160	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
NO935_01165	COG0284	orotidine-5'-phosphate decarboxylase activity
NO935_01200	COG2937	Belongs to the GPAT DAPAT family
NO935_01205	COG3321	synthase
NO935_01205	COG1028	Short-chain dehydrogenase reductase Sdr
NO935_01205	COG0604	alcohol dehydrogenase
NO935_01240	COG1752	Esterase of the alpha-beta hydrolase superfamily
NO935_01250	COG1119	ATPase activity
NO935_01265	COG0517	IMP dehydrogenase activity
NO935_01265	COG1125	glycine betaine transport
NO935_01280	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NO935_01285	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
NO935_01290	COG3550	peptidyl-serine autophosphorylation
NO935_01295	COG1396	sequence-specific DNA binding
NO935_01315	COG0489	protein tyrosine kinase activity
NO935_01320	COG2062	phosphohistidine phosphatase, SixA
NO935_01330	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NO935_01370	COG1968	undecaprenyl-diphosphatase activity
NO935_01375	COG0174	glutamine synthetase
NO935_01380	COG0347	Belongs to the P(II) protein family
NO935_01385	COG0004	ammonium transporteR
NO935_01390	COG3852	Histidine kinase
NO935_01395	COG2204	response regulator
NO935_01400	COG2032	superoxide dismutase activity
NO935_01410	COG2032	superoxide dismutase activity
NO935_01445	COG1196	nuclear chromosome segregation
NO935_01450	COG1196	nuclear chromosome segregation
NO935_01460	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
NO935_01465	COG1074	ATP-dependent DNA helicase activity
NO935_01475	COG3549	Plasmid maintenance system killer
NO935_01560	COG1764	response to oxidative stress
NO935_01565	COG1846	Transcriptional regulator
NO935_01655	COG2211	Major facilitator Superfamily
NO935_01680	COG3693	PFAM glycoside hydrolase, family 10
NO935_01705	COG0246	Mannitol dehydrogenase
NO935_01710	COG1472	Belongs to the glycosyl hydrolase 3 family
NO935_01720	COG4948	Mandelate Racemase Muconate Lactonizing
NO935_01730	COG3661	Belongs to the glycosyl hydrolase 67 family
NO935_01750	COG0037	tRNA processing
NO935_01755	COG2974	May be involved in recombination
NO935_01780	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NO935_01790	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NO935_01800	COG0805	protein transport
NO935_01810	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NO935_01810	COG0519	Catalyzes the synthesis of GMP from XMP
NO935_01825	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NO935_01830	COG0752	glycyl-tRNA synthetase alpha subunit
NO935_01840	COG0457	Tetratricopeptide repeat
NO935_01845	COG4771	TonB-dependent receptor
NO935_01875	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
NO935_01895	COG0523	cobalamin synthesis protein
NO935_01955	COG1960	acyl-CoA dehydrogenase activity
NO935_01960	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NO935_01965	COG4770	biotin carboxylase activity
NO935_02025	COG2351	hydroxyisourate hydrolase activity
NO935_02050	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NO935_02095	COG0084	hydrolase, TatD family'
NO935_02115	COG2814	Major facilitator Superfamily
NO935_02125	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NO935_02130	COG1902	pentaerythritol trinitrate reductase activity
NO935_02160	COG0745	RESPONSE REGULATOR receiver
NO935_02180	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NO935_02185	COG0583	DNA-binding transcription factor activity
NO935_02215	COG0702	epimerase
NO935_02220	COG1733	regulation of RNA biosynthetic process
NO935_02270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NO935_02320	COG2911	Protein conserved in bacteria
NO935_02325	COG0729	surface antigen
NO935_02340	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NO935_02345	COG3118	belongs to the thioredoxin family
NO935_02355	COG2884	Cell division ATP-binding protein ftsE
NO935_02360	COG2177	Part of the ABC transporter FtsEX involved in
NO935_02365	COG2201	protein-glutamate methylesterase activity
NO935_02370	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NO935_02375	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NO935_02385	COG1252	NADH dehydrogenase
NO935_02410	COG0459	protein refolding
NO935_02430	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NO935_02460	COG3386	PFAM SMP-30 Gluconolaconase
NO935_02475	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NO935_02505	COG2353	YceI-like domain
NO935_02545	COG2201	protein-glutamate methylesterase activity
NO935_02595	COG0408	coproporphyrinogen oxidase activity
NO935_02630	COG0129	dihydroxy-acid dehydratase activity
NO935_02640	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NO935_02670	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NO935_02675	COG0318	PFAM AMP-dependent synthetase and ligase
NO935_02680	COG0727	PFAM Uncharacterised protein family (UPF0153)
NO935_02685	COG0596	Alpha beta hydrolase
NO935_02710	COG3177	Filamentation induced by cAMP protein fic
NO935_02715	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NO935_02730	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NO935_02755	COG4191	Histidine kinase
NO935_02760	COG0028	Belongs to the TPP enzyme family
NO935_02775	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
NO935_02780	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NO935_02815	COG5383	Protein conserved in bacteria
NO935_02825	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NO935_02830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NO935_02835	COG1473	amidohydrolase
NO935_02845	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NO935_02845	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NO935_02920	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NO935_02935	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NO935_02940	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NO935_02950	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
NO935_02955	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NO935_02960	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NO935_03010	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NO935_03025	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
NO935_03090	COG3039	Transposase
NO935_03115	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NO935_03135	COG0534	Mate efflux family protein
NO935_03140	COG0616	signal peptide processing
NO935_03150	COG1028	Short-chain dehydrogenase reductase Sdr
NO935_03170	COG0009	L-threonylcarbamoyladenylate synthase
NO935_03175	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NO935_03175	COG1754	DNA topoisomerase type I activity
NO935_03190	COG2922	Belongs to the Smg family
NO935_03195	COG0758	DNA mediated transformation
NO935_03200	COG1652	LysM domain
NO935_03205	COG0242	peptide deformylase activity
NO935_03210	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NO935_03215	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NO935_03215	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NO935_03265	COG1560	Kdo2-lipid A biosynthetic process
NO935_03275	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NO935_03410	COG0358	DNA primase activity
NO935_03415	COG1295	ribonuclease BN
NO935_03425	COG3293	Transposase
NO935_03430	COG1610	YqeY-like protein
NO935_03440	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NO935_03445	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NO935_03490	COG2133	pyrroloquinoline quinone binding
NO935_03495	COG4682	membrane
NO935_03525	COG0531	amino acid
NO935_03555	COG4948	Mandelate Racemase Muconate Lactonizing
NO935_03565	COG3023	N-Acetylmuramoyl-L-alanine amidase
NO935_03570	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
NO935_03640	COG0183	Belongs to the thiolase family
NO935_03685	COG3483	tryptophan 2,3-dioxygenase activity
NO935_03690	COG3104	oligopeptide transport
NO935_03710	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
NO935_03720	COG1320	monovalent cation:proton antiporter activity
NO935_03725	COG2212	antiporter activity
NO935_03735	COG0651	ATP synthesis coupled electron transport
NO935_03740	COG1006	Multisubunit Na H antiporter MnhC subunit
NO935_03745	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NO935_03745	COG2111	Na H antiporter
NO935_03790	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
NO935_03800	COG0456	acetyltransferase
NO935_03820	COG2801	Transposase and inactivated derivatives
NO935_03830	COG4221	oxidoreductase activity
NO935_03890	COG0697	spore germination
NO935_03895	COG4305	rare lipoprotein A
NO935_03900	COG5297	Belongs to the glycosyl hydrolase family 6
NO935_03910	COG1113	amino acid transport
NO935_03920	COG0598	Magnesium transport protein CorA
NO935_03990	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NO935_03990	COG5297	Belongs to the glycosyl hydrolase family 6
NO935_03995	COG0659	secondary active sulfate transmembrane transporter activity
NO935_04035	COG3275	phosphorelay sensor kinase activity
NO935_04045	COG0181	hydroxymethylbilane synthase activity
NO935_04070	COG1505	serine-type exopeptidase activity
NO935_04085	COG3039	Transposase
NO935_04090	COG0436	Aminotransferase
NO935_04120	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
NO935_04150	COG0308	aminopeptidase N
NO935_04155	COG2199	diguanylate cyclase activity
NO935_04200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NO935_04205	COG1077	Cell shape determining protein MreB Mrl
NO935_04210	COG1792	Involved in formation and maintenance of cell shape
NO935_04225	COG0772	Belongs to the SEDS family
NO935_04265	COG1388	LysM domain
NO935_04265	COG3409	Peptidoglycan-binding domain 1 protein
NO935_04265	COG5632	N-Acetylmuramoyl-L-alanine amidase
NO935_04290	COG2951	lytic endotransglycosylase activity
NO935_04295	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NO935_04300	COG1686	Belongs to the peptidase S11 family
NO935_04315	COG2921	Belongs to the UPF0250 family
NO935_04340	COG1056	cytidyltransferase-related domain
NO935_04340	COG1051	belongs to the nudix hydrolase family
NO935_04375	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
NO935_04380	COG0673	inositol 2-dehydrogenase activity
NO935_04385	COG2823	Periplasmic or secreted lipoprotein
NO935_04390	COG4251	negative regulation of phosphorylation
NO935_04395	COG0784	Response regulator, receiver
NO935_04400	COG4191	Histidine kinase
NO935_04405	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NO935_04455	COG3250	beta-galactosidase activity
NO935_04470	COG2188	Transcriptional regulator
NO935_04480	COG1609	Transcriptional regulator
NO935_04485	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NO935_04490	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NO935_04500	COG1215	transferase activity, transferring glycosyl groups
NO935_04505	COG0726	polysaccharide deacetylase
NO935_04505	COG1649	PFAM Uncharacterised BCR, COG1649
NO935_04540	COG3039	Transposase
NO935_04585	COG3039	Transposase
NO935_04590	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NO935_04600	COG3039	Transposase
NO935_04635	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NO935_04675	COG2205	protein histidine kinase activity
NO935_04705	COG3791	Glutathione-dependent formaldehyde-activating
NO935_04730	COG0488	(ABC) transporter
NO935_04750	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NO935_04770	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NO935_04770	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NO935_04790	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NO935_04795	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NO935_04800	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NO935_04820	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NO935_04825	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NO935_04835	COG2205	protein histidine kinase activity
NO935_04840	COG0745	RESPONSE REGULATOR receiver
NO935_04845	COG0277	FAD linked oxidase domain protein
NO935_04850	COG1988	membrane-bound metal-dependent
NO935_04855	COG0792	nuclease activity
NO935_04890	COG0275	rRNA processing
NO935_04895	COG3116	cell division
NO935_04910	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NO935_04915	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NO935_04930	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NO935_04935	COG1181	Belongs to the D-alanine--D-alanine ligase family
NO935_04940	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NO935_04955	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
NO935_04965	COG1388	LysM domain
NO935_04965	COG4942	peptidase
NO935_04980	COG0494	nUDIX hydrolase
NO935_05000	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NO935_05010	COG1028	Short-chain dehydrogenase reductase Sdr
NO935_05010	COG3321	synthase
NO935_05010	COG0604	alcohol dehydrogenase
NO935_05055	COG2226	methyltransferase
NO935_05060	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
NO935_05100	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NO935_05115	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NO935_05125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NO935_05130	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NO935_05140	COG0667	Aldo Keto reductase
NO935_05180	COG1116	anion transmembrane transporter activity
NO935_05185	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
NO935_05195	COG2175	clavaminate synthase activity
NO935_05205	COG4181	ATPase activity
NO935_05220	COG0642	Histidine kinase
NO935_05240	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NO935_05260	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NO935_05285	COG2967	ApaG domain
NO935_05290	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NO935_05300	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NO935_05315	COG0123	including yeast histone deacetylase and acetoin utilization protein
NO935_05320	COG2096	Adenosyltransferase
NO935_05330	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NO935_05335	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NO935_05375	COG0583	DNA-binding transcription factor activity
NO935_05380	COG0318	PFAM AMP-dependent synthetase and ligase
NO935_05390	COG1024	Enoyl-CoA hydratase
NO935_05410	COG3386	PFAM SMP-30 Gluconolaconase
NO935_05520	COG2197	response regulator
NO935_05550	COG0386	Belongs to the glutathione peroxidase family
NO935_05565	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NO935_05570	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NO935_05575	COG0583	DNA-binding transcription factor activity
NO935_05580	COG3634	alkyl hydroperoxide reductase activity
NO935_05590	COG2890	protein-(glutamine-N5) methyltransferase activity
NO935_05630	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NO935_05630	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NO935_05645	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
NO935_05670	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
NO935_05695	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NO935_05705	COG1404	Belongs to the peptidase S8 family
NO935_05710	COG1404	Belongs to the peptidase S8 family
NO935_05715	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NO935_05745	COG1295	ribonuclease BN
NO935_05750	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NO935_05770	COG0521	Mo-molybdopterin cofactor biosynthetic process
NO935_05780	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NO935_05785	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NO935_05795	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
NO935_05810	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NO935_05820	COG0193	aminoacyl-tRNA hydrolase activity
NO935_05825	COG0012	GTP binding
NO935_05855	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NO935_05860	COG0250	Participates in transcription elongation, termination and antitermination
NO935_05865	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NO935_05875	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NO935_05880	COG0222	ribosome binding
NO935_05885	COG0085	RNA polymerase activity
NO935_05890	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NO935_05895	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NO935_05900	COG0049	tRNA binding
NO935_05920	COG0051	transcription antitermination factor activity, RNA binding
NO935_05925	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NO935_05930	COG0088	Forms part of the polypeptide exit tunnel
NO935_05935	COG0089	rRNA binding
NO935_05950	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NO935_05960	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NO935_05965	COG0255	Belongs to the universal ribosomal protein uL29 family
NO935_05970	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NO935_05975	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NO935_05985	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NO935_06015	COG1841	ribosomal large subunit assembly
NO935_06025	COG0201	protein transport
NO935_06035	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NO935_06040	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NO935_06050	COG0203	ribosomal protein L17
NO935_06110	COG3551	Protein conserved in bacteria
NO935_06140	COG2194	sulfuric ester hydrolase activity
NO935_06150	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NO935_06155	COG0745	RESPONSE REGULATOR receiver
NO935_06160	COG0642	Histidine kinase
NO935_06170	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
NO935_06175	COG2894	cell division
NO935_06195	COG4585	Histidine kinase
NO935_06200	COG2197	response regulator
NO935_06215	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NO935_06240	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NO935_06315	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NO935_06325	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NO935_06350	COG3039	Transposase
NO935_06365	COG3039	Transposase
NO935_06380	COG3039	Transposase
NO935_06410	COG1741	Belongs to the pirin family
NO935_06420	COG1515	deoxyribonuclease V activity
NO935_06425	COG0588	phosphoglycerate mutase activity
NO935_06440	COG3590	peptidase
NO935_06455	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NO935_06460	COG2199	diguanylate cyclase activity
NO935_06460	COG2200	EAL domain
NO935_06460	COG2202	Pas domain
NO935_06465	COG0835	chemotaxis
NO935_06470	COG0840	transmembrane signaling receptor activity
NO935_06475	COG0643	Histidine kinase
NO935_06475	COG2198	Histidine kinase
NO935_06490	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NO935_06500	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
NO935_06540	COG3039	Transposase
NO935_06600	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NO935_06605	COG0735	belongs to the Fur family
NO935_06665	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NO935_06670	COG0084	hydrolase, TatD family'
NO935_06685	COG1960	acyl-CoA dehydrogenase activity
NO935_06700	COG0367	asparagine synthase
NO935_06710	COG0305	Participates in initiation and elongation during chromosome replication
NO935_06715	COG0415	Belongs to the DNA photolyase family
NO935_06845	COG5001	Diguanylate cyclase
NO935_06845	COG5002	protein histidine kinase activity
NO935_06850	COG1187	pseudouridine synthase activity
NO935_06870	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NO935_06880	COG0475	glutathione-regulated potassium exporter activity
NO935_06885	COG5000	phosphorelay sensor kinase activity
NO935_06885	COG5002	protein histidine kinase activity
NO935_06890	COG0745	RESPONSE REGULATOR receiver
NO935_06920	COG1132	(ABC) transporter
NO935_06950	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NO935_06960	COG4969	Belongs to the N-Me-Phe pilin family
NO935_06965	COG2194	sulfuric ester hydrolase activity
NO935_06985	COG2184	nucleotidyltransferase activity
NO935_07010	COG0045	succinate-CoA ligase (ADP-forming) activity
NO935_07015	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NO935_07025	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NO935_07025	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NO935_07030	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NO935_07035	COG0564	pseudouridine synthase activity
NO935_07060	COG3387	PFAM Glycoside hydrolase 15-related
NO935_07065	COG1877	trehalose-phosphatase activity
NO935_07105	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
NO935_07130	COG1946	Acyl-CoA thioesterase
NO935_07145	COG0824	Thioesterase
NO935_07150	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NO935_07160	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NO935_07165	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NO935_07170	COG0268	Binds directly to 16S ribosomal RNA
NO935_07175	COG0728	peptidoglycan biosynthetic process
NO935_07180	COG0196	riboflavin kinase activity
NO935_07190	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NO935_07195	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NO935_07210	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NO935_07215	COG1845	cytochrome c oxidase, subunit III
NO935_07220	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NO935_07245	COG3209	COG3209 Rhs family protein
NO935_07260	COG3328	transposase activity
NO935_07280	COG3209	COG3209 Rhs family protein
NO935_07280	COG3209	COG3209 Rhs family protein
NO935_07305	COG3039	Transposase
NO935_07420	COG0632	four-way junction helicase activity
NO935_07430	COG2255	four-way junction helicase activity
NO935_07435	COG0824	Thioesterase
NO935_07445	COG0848	biopolymer transport protein
NO935_07460	COG2885	chlorophyll binding
NO935_07470	COG0602	queuosine metabolic process
NO935_07500	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NO935_07525	COG0514	ATP-dependent DNA helicase (RecQ)
NO935_07530	COG0783	Belongs to the Dps family
NO935_07535	COG1643	Atp-dependent helicase
NO935_07560	COG0535	radical SAM domain protein
NO935_07565	COG0535	radical SAM domain protein
NO935_07585	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NO935_07595	COG1215	transferase activity, transferring glycosyl groups
NO935_07600	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NO935_07610	COG1199	ATP-dependent helicase activity
NO935_07630	COG0189	ligase activity
NO935_07645	COG0835	chemotaxis
NO935_07650	COG0840	transmembrane signaling receptor activity
NO935_07655	COG0643	Histidine kinase
NO935_07655	COG2198	Histidine kinase
NO935_07655	COG0784	Response regulator, receiver
NO935_07685	COG2304	oxidoreductase activity
NO935_07690	COG2304	oxidoreductase activity
NO935_07700	COG1446	asparaginase
NO935_07745	COG3537	Alpha-1,2-mannosidase
NO935_07825	COG1472	Belongs to the glycosyl hydrolase 3 family
NO935_07835	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NO935_07845	COG3858	chitin binding
NO935_07845	COG1388	LysM domain
NO935_07860	COG0837	glucose binding
NO935_07865	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NO935_07875	COG0494	nUDIX hydrolase
NO935_07885	COG3956	TIGRFAM MazG family protein
NO935_07900	COG0330	HflC and HflK could
NO935_07915	COG0509	glycine decarboxylation via glycine cleavage system
NO935_07945	COG1960	acyl-CoA dehydrogenase activity
NO935_07955	COG1309	transcriptional regulator
NO935_07960	COG4771	TonB-dependent receptor
NO935_07970	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NO935_07980	COG0463	Glycosyl transferase, family 2
NO935_08005	COG1272	protein, Hemolysin III
NO935_08015	COG0739	heme binding
NO935_08020	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NO935_08025	COG0626	cystathionine gamma-synthase activity
NO935_08035	COG1760	l-serine dehydratase
NO935_08050	COG2353	YceI-like domain
NO935_08060	COG2353	YceI-like domain
NO935_08130	COG1960	acyl-CoA dehydrogenase activity
NO935_08135	COG1024	Enoyl-CoA hydratase
NO935_08155	COG1024	Enoyl-CoA hydratase
NO935_08155	COG1250	3-hydroxyacyl-CoA dehydrogenase
NO935_08170	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NO935_08200	COG1381	Involved in DNA repair and RecF pathway recombination
NO935_08215	COG2954	triphosphatase activity
NO935_08235	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
NO935_08240	COG3046	protein related to deoxyribodipyrimidine photolyase
NO935_08250	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NO935_08255	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NO935_08260	COG1278	Cold shock
NO935_08285	COG1201	RNA secondary structure unwinding
NO935_08290	COG1793	dna ligase
NO935_08300	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
NO935_08300	COG1793	dna ligase
NO935_08330	COG0183	Belongs to the thiolase family
NO935_08350	COG1451	nucleotide metabolic process
NO935_08365	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NO935_08375	COG3039	Transposase
NO935_08410	COG1047	Peptidyl-prolyl cis-trans
NO935_08430	COG2824	Alkylphosphonate utilization operon protein PhnA
NO935_08440	COG1902	pentaerythritol trinitrate reductase activity
NO935_08445	COG2814	Major facilitator Superfamily
NO935_08480	COG0392	lysyltransferase activity
NO935_08480	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NO935_08490	COG0251	oxidation-reduction process
NO935_08495	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NO935_08510	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NO935_08535	COG1595	DNA-templated transcription, initiation
NO935_08550	COG2878	Part of a membrane complex involved in electron transport
NO935_08560	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NO935_08560	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NO935_08580	COG0833	amino acid
NO935_08585	COG2040	homocysteine
NO935_08605	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NO935_08645	COG0529	Catalyzes the synthesis of activated sulfate
NO935_08645	COG2895	sulfate adenylyltransferase (ATP) activity
NO935_08690	COG1981	membrane
NO935_08720	COG4771	TonB-dependent receptor
NO935_08730	COG0825	malonyl-CoA metabolic process
NO935_08750	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NO935_08755	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NO935_08780	COG0750	zinc metalloprotease
NO935_08790	COG0575	Belongs to the CDS family
NO935_08800	COG0233	cytoplasmic translational termination
NO935_08815	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NO935_08875	COG1393	Belongs to the ArsC family
NO935_08885	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NO935_08890	COG0367	asparagine synthase
NO935_08900	COG4774	siderophore transport
NO935_08925	COG2207	Transcriptional regulator
NO935_08940	COG1566	PFAM secretion protein HlyD family protein
NO935_08945	COG2814	Major facilitator Superfamily
NO935_08990	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NO935_09000	COG1960	acyl-CoA dehydrogenase activity
NO935_09015	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NO935_09025	COG2914	Belongs to the UPF0125 (RnfH) family
NO935_09030	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NO935_09040	COG0497	DNA recombination
NO935_09050	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NO935_09060	COG0484	heat shock protein binding
NO935_09065	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
NO935_09070	COG0287	Prephenate dehydrogenase
NO935_09070	COG1605	Chorismate mutase
NO935_09095	COG1132	(ABC) transporter
NO935_09130	COG2850	peptidyl-arginine hydroxylation
NO935_09210	COG1131	(ABC) transporter
NO935_09215	COG1725	Transcriptional regulator
NO935_09225	COG0386	Belongs to the glutathione peroxidase family
NO935_09245	COG2900	Belongs to the SlyX family
NO935_09260	COG1609	Transcriptional regulator
NO935_09270	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NO935_09280	COG1410	methionine synthase
NO935_09280	COG0646	methionine synthase
NO935_09285	COG1410	methionine synthase
NO935_09285	COG0646	methionine synthase
NO935_09290	COG2226	methyltransferase
NO935_09295	COG1960	acyl-CoA dehydrogenase activity
NO935_09320	COG0557	exoribonuclease II activity
NO935_09335	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NO935_09345	COG3039	Transposase
NO935_09370	COG3328	transposase activity
NO935_09460	COG3039	Transposase
NO935_09470	COG0583	DNA-binding transcription factor activity
NO935_09530	COG3209	COG3209 Rhs family protein
NO935_09565	COG0643	Histidine kinase
NO935_09565	COG2198	Histidine kinase
NO935_09565	COG0784	Response regulator, receiver
NO935_09620	COG1684	flagellar biosynthetic protein fliR
NO935_09635	COG3190	flagellar
NO935_09685	COG1677	Flagellar hook-basal body complex protein FliE
NO935_09715	COG1028	Short-chain dehydrogenase reductase Sdr
NO935_09725	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NO935_09745	COG2201	protein-glutamate methylesterase activity
NO935_09780	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NO935_09785	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NO935_09820	COG4787	bacterial-type flagellum-dependent cell motility
NO935_09830	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
NO935_09835	COG1558	bacterial-type flagellum-dependent cell motility
NO935_09845	COG0835	chemotaxis
NO935_09845	COG0784	Response regulator, receiver
NO935_09865	COG5002	protein histidine kinase activity
NO935_09875	COG4585	Histidine kinase
NO935_09880	COG5001	Diguanylate cyclase
NO935_09905	COG0482	sulfurtransferase activity
NO935_09920	COG0542	response to heat
NO935_09955	COG0492	ferredoxin-NADP+ reductase activity
NO935_09960	COG1674	ftsk spoiiie
NO935_09980	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NO935_10000	COG0038	chloride channel
NO935_10005	COG0183	Belongs to the thiolase family
NO935_10010	COG1250	3-hydroxyacyl-CoA dehydrogenase
NO935_10010	COG1024	Enoyl-CoA hydratase
NO935_10025	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NO935_10035	COG1426	Protein conserved in bacteria
NO935_10045	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NO935_10055	COG0303	'Molybdopterin
NO935_10125	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NO935_10135	COG3039	Transposase
NO935_10165	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
NO935_10170	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NO935_10180	COG0531	amino acid
NO935_10185	COG0531	amino acid
NO935_10195	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NO935_10200	COG0277	FAD linked oxidase domain protein
NO935_10260	COG4133	protoheme IX ABC transporter activity
NO935_10265	COG0436	Aminotransferase
NO935_10290	COG1187	pseudouridine synthase activity
NO935_10295	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NO935_10300	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NO935_10305	COG2350	Protein conserved in bacteria
NO935_10335	COG1175	transmembrane transport
NO935_10340	COG0395	ABC-type sugar transport system, permease component
NO935_10365	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NO935_10375	COG2957	Belongs to the agmatine deiminase family
NO935_10390	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NO935_10395	COG0539	negative regulation of cytoplasmic translation
NO935_10400	COG0776	regulation of translation
NO935_10410	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
NO935_10415	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NO935_10425	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NO935_10445	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NO935_10465	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NO935_10470	COG0583	DNA-binding transcription factor activity
NO935_10485	COG1028	Short-chain dehydrogenase reductase Sdr
NO935_10520	COG1914	H( )-stimulated, divalent metal cation uptake system
NO935_10540	COG0668	transmembrane transport
NO935_10580	COG3039	Transposase
NO935_10590	COG1028	Short-chain dehydrogenase reductase Sdr
NO935_10595	COG1183	phosphatidylcholine synthase activity
NO935_10605	COG3243	poly(R)-hydroxyalkanoic acid synthase
NO935_10620	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NO935_10620	COG0723	plastoquinol--plastocyanin reductase activity
NO935_10630	COG2183	response to ionizing radiation
NO935_10645	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
NO935_10660	COG0671	phosphoesterase, PA-phosphatase related
NO935_10685	COG0697	spore germination
NO935_10715	COG1012	belongs to the aldehyde dehydrogenase family
NO935_10750	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NO935_10765	COG0124	histidyl-tRNA synthetase
NO935_10795	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NO935_10810	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
NO935_10810	COG0131	Imidazoleglycerol-phosphate dehydratase
NO935_10820	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NO935_10830	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NO935_10830	COG0140	phosphoribosyl-ATP diphosphatase activity
NO935_11000	COG2201	protein-glutamate methylesterase activity
NO935_11030	COG3328	transposase activity
NO935_11065	COG0322	excinuclease ABC activity
NO935_11075	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NO935_11085	COG1663	tetraacyldisaccharide 4'-kinase activity
NO935_11100	COG0811	peptide transport
NO935_11125	COG4591	ABC-type transport system involved in lipoprotein release permease component
NO935_11140	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NO935_11155	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
NO935_11170	COG0354	folic acid binding
NO935_11185	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NO935_11195	COG0363	glucosamine-6-phosphate deaminase activity
NO935_11200	COG0129	dihydroxy-acid dehydratase activity
NO935_11205	COG0800	Aldolase
NO935_11245	COG0784	Response regulator, receiver
NO935_11245	COG2205	protein histidine kinase activity
NO935_11245	COG5002	protein histidine kinase activity
NO935_11270	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NO935_11275	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NO935_11280	COG0431	NADPH-dependent FMN reductase
NO935_11285	COG1393	Belongs to the ArsC family
NO935_11290	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NO935_11310	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NO935_11335	COG3039	Transposase
NO935_11345	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NO935_11365	COG1247	-acetyltransferase
NO935_11445	COG0386	Belongs to the glutathione peroxidase family
NO935_11530	COG3706	GGDEF domain
NO935_11530	COG4251	negative regulation of phosphorylation
NO935_11530	COG5001	Diguanylate cyclase
NO935_11530	COG2203	Gaf domain
NO935_11545	COG1472	Belongs to the glycosyl hydrolase 3 family
NO935_11575	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NO935_11580	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NO935_11590	COG0617	tRNA 3'-terminal CCA addition
NO935_11600	COG1469	GTP cyclohydrolase I activity
NO935_11605	COG0860	N-Acetylmuramoyl-L-alanine amidase
NO935_11650	COG4566	intracellular signal transduction
NO935_11680	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NO935_11685	COG0077	Prephenate dehydratase
NO935_11685	COG1605	Chorismate mutase
NO935_11695	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NO935_11735	COG1228	amidohydrolase
NO935_11740	COG2986	histidine ammonia-lyase
NO935_11750	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NO935_11775	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NO935_11790	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
NO935_11810	COG3115	cell septum assembly
NO935_11830	COG0360	Binds together with S18 to 16S ribosomal RNA
NO935_11835	COG0316	Belongs to the HesB IscA family
NO935_11865	COG3039	Transposase
NO935_11875	COG0288	reversible hydration of carbon dioxide
NO935_11890	COG3844	kynureninase activity
NO935_11900	COG2925	Exonuclease
NO935_11910	COG0667	Aldo Keto reductase
NO935_11935	COG0116	Belongs to the methyltransferase superfamily
NO935_11935	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NO935_11980	COG0494	nUDIX hydrolase
NO935_11995	COG1024	Enoyl-CoA hydratase
NO935_12005	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NO935_12040	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NO935_12045	COG0573	inorganic phosphate transmembrane transporter activity
NO935_12060	COG0704	Plays a role in the regulation of phosphate uptake
NO935_12070	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NO935_12105	COG3039	Transposase
NO935_12115	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NO935_12120	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NO935_12125	COG1862	Preprotein translocase
NO935_12130	COG0343	queuine tRNA-ribosyltransferase activity
NO935_12165	COG3039	Transposase
NO935_12215	COG0405	Gamma-glutamyltransferase
NO935_12220	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NO935_12230	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NO935_12235	COG0742	ribosomal rna small subunit methyltransferase
NO935_12265	COG1858	cytochrome C peroxidase
NO935_12340	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NO935_12345	COG4988	ABC transporter
NO935_12380	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NO935_12400	COG0165	Argininosuccinate lyase
NO935_12415	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NO935_12420	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NO935_12430	COG0137	argininosuccinate synthase activity
NO935_12435	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NO935_12450	COG2166	iron-sulfur cluster assembly
NO935_12480	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NO935_12510	COG3039	Transposase
NO935_12530	COG4677	pectinesterase activity
NO935_12560	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NO935_12565	COG0402	S-adenosylhomocysteine deaminase activity
NO935_12580	COG1509	lysine 2,3-aminomutase activity
NO935_12585	COG3300	MHYT domain
NO935_12585	COG5001	Diguanylate cyclase
NO935_12600	COG0483	inositol monophosphate 1-phosphatase activity
NO935_12605	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NO935_12625	COG0488	(ABC) transporter
NO935_12630	COG0513	Belongs to the DEAD box helicase family
NO935_12635	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NO935_12640	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
NO935_12650	COG0625	glutathione transferase activity
NO935_12660	COG1671	Belongs to the UPF0178 family
NO935_12665	COG4681	YaeQ
NO935_12670	COG2081	HI0933 family
NO935_12680	COG0501	Belongs to the peptidase M48B family
NO935_12690	COG1028	Short-chain dehydrogenase reductase Sdr
NO935_12710	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NO935_12715	COG0860	N-Acetylmuramoyl-L-alanine amidase
NO935_12720	COG0802	atpase or kinase
NO935_12725	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NO935_12725	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NO935_12730	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NO935_12750	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NO935_12830	COG3039	Transposase
NO935_12845	COG2094	Belongs to the DNA glycosylase MPG family
NO935_12870	COG2969	positive regulation of protein catabolic process
NO935_12875	COG0625	glutathione transferase activity
NO935_12880	COG2857	Cytochrome c1
NO935_12885	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NO935_12890	COG0723	plastoquinol--plastocyanin reductase activity
NO935_12895	COG0741	lytic transglycosylase activity
NO935_12920	COG1702	phosphate starvation-inducible protein PhoH
NO935_12940	COG4535	Mg2 and Co2 transporter CorC
NO935_12955	COG1012	belongs to the aldehyde dehydrogenase family
NO935_12975	COG3842	ATPase activity
NO935_13010	COG0174	glutamine synthetase
NO935_13015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NO935_13025	COG0477	Major facilitator Superfamily
NO935_13035	COG0243	molybdopterin cofactor binding
NO935_13045	COG2223	nitrite transmembrane transporter activity
NO935_13050	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NO935_13055	COG1121	(ABC) transporter
NO935_13065	COG2733	membrane
NO935_13070	COG2205	protein histidine kinase activity
NO935_13070	COG5002	protein histidine kinase activity
NO935_13070	COG0784	Response regulator, receiver
NO935_13100	COG3039	Transposase
NO935_13105	COG2902	Dehydrogenase
NO935_13115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NO935_13120	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NO935_13145	COG1609	Transcriptional regulator
NO935_13150	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NO935_13150	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NO935_13155	COG1105	Belongs to the carbohydrate kinase PfkB family
NO935_13160	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NO935_13160	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NO935_13170	COG3039	Transposase
NO935_13185	COG3039	Transposase
NO935_13210	COG3039	Transposase
NO935_13270	COG3409	Peptidoglycan-binding domain 1 protein
NO935_13270	COG3501	Rhs element vgr protein
NO935_13310	COG3039	Transposase
NO935_13360	COG4771	TonB-dependent receptor
NO935_13370	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NO935_13390	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NO935_13395	COG1360	Flagellar Motor Protein
NO935_13400	COG1192	Involved in chromosome partitioning
NO935_13405	COG0835	chemotaxis
NO935_13415	COG0745	RESPONSE REGULATOR receiver
NO935_13445	COG0840	transmembrane signaling receptor activity
NO935_13455	COG0840	transmembrane signaling receptor activity
NO935_13465	COG0840	transmembrane signaling receptor activity
NO935_13470	COG0840	transmembrane signaling receptor activity
NO935_13475	COG0840	transmembrane signaling receptor activity
NO935_13480	COG0840	transmembrane signaling receptor activity
NO935_13500	COG0835	chemotaxis
NO935_13515	COG3039	Transposase
NO935_13570	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NO935_13600	COG0318	PFAM AMP-dependent synthetase and ligase
NO935_13605	COG1024	Enoyl-CoA hydratase
NO935_13610	COG2205	protein histidine kinase activity
NO935_13610	COG0784	Response regulator, receiver
NO935_13610	COG2198	Histidine kinase
NO935_13675	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NO935_13685	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NO935_13690	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NO935_13700	COG0505	Belongs to the CarA family
NO935_13705	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NO935_13715	COG2258	MOSC domain
NO935_13720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NO935_13765	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NO935_13785	COG0477	Major facilitator Superfamily
NO935_13795	COG1070	Carbohydrate kinase
NO935_13805	COG1501	Belongs to the glycosyl hydrolase 31 family
NO935_13820	COG0800	Aldolase
NO935_13825	COG4948	Mandelate Racemase Muconate Lactonizing
NO935_13835	COG3734	2-keto-3-deoxy-galactonokinase
NO935_13840	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
NO935_13850	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NO935_13865	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NO935_13870	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NO935_13880	COG0351	phosphomethylpyrimidine kinase
NO935_13905	COG0583	DNA-binding transcription factor activity
NO935_13910	COG1741	Belongs to the pirin family
NO935_13935	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NO935_13940	COG0305	Participates in initiation and elongation during chromosome replication
NO935_13960	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NO935_13965	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NO935_13970	COG2137	regulation of response to DNA damage stimulus
NO935_13975	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NO935_13985	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NO935_13990	COG1546	Belongs to the CinA family
NO935_13995	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NO935_14005	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NO935_14010	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NO935_14020	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
NO935_14025	COG1534	Rna-binding protein
NO935_14040	COG1238	metal cluster binding
NO935_14045	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NO935_14050	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NO935_14055	COG2840	Smr protein MutS2
NO935_14065	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NO935_14075	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NO935_14080	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NO935_14085	COG0148	phosphopyruvate hydratase activity
NO935_14095	COG2877	3-deoxy-8-phosphooctulonate synthase activity
NO935_14100	COG0504	CTP synthase activity
NO935_14130	COG0306	phosphate transporter
NO935_14140	COG1253	flavin adenine dinucleotide binding
NO935_14155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NO935_14165	COG0477	Major facilitator Superfamily
NO935_14175	COG1132	(ABC) transporter
NO935_14180	COG1136	(ABC) transporter
NO935_14195	COG0438	transferase activity, transferring glycosyl groups
NO935_14205	COG2264	protein methyltransferase activity
NO935_14235	COG2244	polysaccharide biosynthetic process
NO935_14285	COG1595	DNA-templated transcription, initiation
NO935_14300	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NO935_14320	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NO935_14365	COG2201	protein-glutamate methylesterase activity
NO935_14390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NO935_14445	COG1858	cytochrome C peroxidase
NO935_14475	COG0515	serine threonine protein kinase
NO935_14480	COG0631	protein serine/threonine phosphatase activity
NO935_14580	COG3039	Transposase
NO935_14625	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
NO935_14625	COG0316	Belongs to the HesB IscA family
NO935_14630	COG2154	pterin-4-alpha-carbinolamine dehydratase
NO935_14645	COG3064	Membrane
NO935_14655	COG1530	ribonuclease E activity
NO935_14670	COG1054	Belongs to the UPF0176 family
NO935_14690	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
NO935_14725	COG3039	Transposase
NO935_14730	COG3039	Transposase
NO935_14765	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NO935_14765	COG1648	precorrin-2 dehydrogenase activity
NO935_14790	COG0746	molybdenum cofactor guanylyltransferase activity
NO935_14840	COG3328	transposase activity
NO935_14865	COG4206	TonB-dependent receptor
NO935_14895	COG0531	amino acid
NO935_14910	COG0006	proline dipeptidase activity
NO935_14920	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NO935_14935	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NO935_14940	COG3938	Belongs to the proline racemase family
NO935_14950	COG0552	protein localization to endoplasmic reticulum
NO935_14970	COG0784	Response regulator, receiver
NO935_14970	COG4191	Histidine kinase
NO935_15050	COG3040	lipid binding
NO935_15090	COG0438	transferase activity, transferring glycosyl groups
NO935_15100	COG0438	transferase activity, transferring glycosyl groups
NO935_15105	COG0438	transferase activity, transferring glycosyl groups
NO935_15175	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NO935_15210	COG0556	nucleotide-excision repair
NO935_15215	COG4969	Belongs to the N-Me-Phe pilin family
NO935_15255	COG1611	Belongs to the LOG family
NO935_15270	COG2095	MarC family integral membrane protein
NO935_15280	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NO935_15315	COG1185	polyribonucleotide nucleotidyltransferase activity
NO935_15320	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NO935_15340	COG0195	Participates in both transcription termination and antitermination
NO935_15345	COG0779	Required for maturation of 30S ribosomal subunits
NO935_15355	COG1007	ATP synthesis coupled electron transport
NO935_15385	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NO935_15390	COG1034	ATP synthesis coupled electron transport
NO935_15395	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
NO935_15400	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
NO935_15405	COG0649	NAD binding
NO935_15410	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NO935_15420	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NO935_15435	COG0149	triose-phosphate isomerase activity
NO935_15475	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NO935_15480	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NO935_15485	COG0159	tryptophan synthase activity
NO935_15495	COG0133	tryptophan synthase activity
NO935_15505	COG0135	phosphoribosylanthranilate isomerase activity
NO935_15510	COG0101	tRNA pseudouridine synthase activity
NO935_15530	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NO935_15535	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NO935_15540	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NO935_15545	COG2890	protein-(glutamine-N5) methyltransferase activity
NO935_15585	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NO935_15615	COG0717	Belongs to the dCTP deaminase family
NO935_15620	COG0489	protein tyrosine kinase activity
NO935_15660	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NO935_15665	COG2311	Membrane
NO935_15670	COG1047	Peptidyl-prolyl cis-trans
NO935_15675	COG0791	NLP P60 protein
NO935_15680	COG0791	NLP P60 protein
NO935_15700	COG1785	Belongs to the alkaline phosphatase family
NO935_15705	COG0037	tRNA processing
NO935_15710	COG1722	exodeoxyribonuclease VII activity
NO935_15715	COG0142	geranyltranstransferase activity
NO935_15735	COG0312	modulator of DNA gyrase
NO935_15740	COG3028	Belongs to the UPF0307 family
NO935_15745	COG0312	modulator of DNA gyrase
NO935_15755	COG3164	Protein of unknown function
NO935_15770	COG2968	Membrane
NO935_15800	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NO935_15825	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NO935_15850	COG3118	belongs to the thioredoxin family
NO935_15915	COG3039	Transposase
NO935_15995	COG2022	thiamine diphosphate biosynthetic process
NO935_16005	COG0471	metal ion transport
NO935_16005	COG3273	potassium ion transport
NO935_16035	COG1970	mechanosensitive ion channel activity
NO935_16055	COG2272	Belongs to the type-B carboxylesterase lipase family
NO935_16060	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NO935_16080	COG0308	aminopeptidase N
NO935_16085	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NO935_16095	COG0529	Catalyzes the synthesis of activated sulfate
NO935_16095	COG2895	sulfate adenylyltransferase (ATP) activity
NO935_16100	COG0175	sulfate reduction
NO935_16105	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NO935_16110	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NO935_16115	COG0175	sulfate reduction
NO935_16135	COG0784	Response regulator, receiver
NO935_16135	COG2198	Histidine kinase
NO935_16135	COG2205	protein histidine kinase activity
NO935_16180	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
NO935_16185	COG3588	fructose-bisphosphate aldolase
NO935_16190	COG0469	pyruvate kinase activity
NO935_16230	COG0753	catalase activity
NO935_16255	COG2207	Transcriptional regulator
NO935_16255	COG1917	Cupin 2, conserved barrel domain protein
NO935_16275	COG0823	Involved in the tonB-independent uptake of proteins
NO935_16275	COG1506	peptidase
NO935_16295	COG1297	OPT oligopeptide transporter protein
NO935_16310	COG0587	DNA-directed DNA polymerase activity
NO935_16385	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
NO935_16400	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
NO935_16405	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
NO935_16410	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
NO935_16430	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
NO935_16445	COG0732	type I restriction modification DNA specificity domain
NO935_16450	COG3039	Transposase
NO935_16455	COG0732	type I restriction modification DNA specificity domain
NO935_16660	COG3179	chitinase
NO935_16730	COG1741	Belongs to the pirin family
NO935_16735	COG1966	Carbon starvation protein
NO935_16740	COG2879	small protein
NO935_16765	COG3039	Transposase
NO935_16785	COG2203	Gaf domain
NO935_16785	COG4251	negative regulation of phosphorylation
NO935_16785	COG5001	Diguanylate cyclase
NO935_16785	COG3706	GGDEF domain
NO935_16790	COG0629	single-stranded DNA binding
NO935_16795	COG0142	geranyltranstransferase activity
NO935_16820	COG0527	aspartate kinase activity
NO935_16830	COG0384	phenazine biosynthesis protein PhzF
NO935_16840	COG1764	response to oxidative stress
NO935_16855	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NO935_16860	COG1678	Uncharacterized ACR, COG1678
NO935_16875	COG0519	Catalyzes the synthesis of GMP from XMP
NO935_16905	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NO935_16965	COG1959	2 iron, 2 sulfur cluster binding
NO935_16970	COG0719	Fe-S assembly protein
NO935_16975	COG0396	ATPase activity
NO935_16980	COG0719	Fe-S assembly protein
NO935_16985	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NO935_17000	COG2146	nitrite reductase [NAD(P)H] activity
NO935_17035	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NO935_17050	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NO935_17060	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
NO935_17065	COG0174	glutamine synthetase
NO935_17070	COG3328	transposase activity
NO935_17095	COG0326	Molecular chaperone. Has ATPase activity
NO935_17100	COG2207	Transcriptional regulator
NO935_17125	COG0657	acetylesterase activity
NO935_17125	COG2755	lipolytic protein G-D-S-L family
NO935_17150	COG0488	(ABC) transporter
NO935_17185	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NO935_17185	COG4651	solute:proton antiporter activity
NO935_17200	COG4772	TonB-dependent receptor
NO935_17210	COG4264	IucA IucC family
NO935_17215	COG2814	Major facilitator Superfamily
NO935_17225	COG0019	diaminopimelate decarboxylase activity
NO935_17290	COG4206	TonB-dependent receptor
NO935_17315	COG3039	Transposase
NO935_17330	COG0542	response to heat
NO935_17380	COG0336	Belongs to the RNA methyltransferase TrmD family
NO935_17385	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NO935_17390	COG0228	four-way junction DNA binding
NO935_17410	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NO935_17420	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NO935_17465	COG1555	photosystem II stabilization
NO935_17470	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NO935_17485	COG3178	'Phosphotransferase
NO935_17490	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NO935_17500	COG0628	permease
NO935_17510	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NO935_17525	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NO935_17545	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NO935_17550	COG0271	Belongs to the BolA IbaG family
NO935_17560	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
NO935_17570	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
NO935_17575	COG1137	ATPase activity
NO935_17590	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NO935_17595	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NO935_17600	COG1660	Displays ATPase and GTPase activities
NO935_17615	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NO935_17620	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NO935_17625	COG2239	Acts as a magnesium transporter
NO935_17635	COG1294	oxidase, subunit
NO935_17640	COG1271	oxidase subunit
NO935_17655	COG1113	amino acid transport
NO935_17670	COG2197	response regulator
NO935_17675	COG0531	amino acid
NO935_17735	COG0754	glutathionylspermidine amidase activity
NO935_17760	COG1842	Phage shock protein A
NO935_17775	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NO935_17790	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NO935_17820	COG2201	protein-glutamate methylesterase activity
NO935_17865	COG2201	protein-glutamate methylesterase activity
NO935_17885	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NO935_17945	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NO935_17950	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NO935_17980	COG3039	Transposase
NO935_17995	COG0745	RESPONSE REGULATOR receiver
NO935_18000	COG2205	protein histidine kinase activity
NO935_18020	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NO935_18050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NO935_18050	COG3453	Protein conserved in bacteria
NO935_18055	COG0725	ABC transporter, periplasmic molybdate-binding protein
NO935_18060	COG4149	molybdate abc transporter
NO935_18065	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
NO935_18085	COG0642	Histidine kinase
NO935_18100	COG1028	Short-chain dehydrogenase reductase Sdr
NO935_18115	COG1022	Amp-dependent synthetase and ligase
NO935_18140	COG1376	ErfK ybiS ycfS ynhG family protein
NO935_18145	COG0739	heme binding
NO935_18155	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NO935_18160	COG1301	dicarboxylic acid transport
NO935_18180	COG2304	oxidoreductase activity
NO935_18200	COG0714	Associated with various cellular activities
NO935_18240	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
NO935_18265	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NO935_18275	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NO935_18300	COG1561	YicC-like family, N-terminal region
NO935_18305	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NO935_18320	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NO935_18355	COG0006	proline dipeptidase activity
NO935_18380	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NO935_18390	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NO935_18400	COG2912	Transglutaminase-like superfamily
NO935_18405	COG1773	rubredoxin
NO935_18410	COG0352	thiamine-phosphate diphosphorylase activity
NO935_18435	COG0281	malic enzyme
NO935_18435	COG0280	phosphate acetyltransferase
NO935_18455	COG4191	Histidine kinase
NO935_18470	COG0583	DNA-binding transcription factor activity
NO935_18490	COG2197	response regulator
NO935_18500	COG0642	Histidine kinase
NO935_18515	COG2851	Citrate transporter
NO935_18520	COG1028	Short-chain dehydrogenase reductase Sdr
NO935_18525	COG1609	Transcriptional regulator
NO935_18535	COG2211	Major facilitator Superfamily
NO935_18560	COG1162	GTPase activity
NO935_18585	COG0726	polysaccharide deacetylase
NO935_18590	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NO935_18650	COG0242	peptide deformylase activity
NO935_18670	COG0714	Associated with various cellular activities
NO935_18690	COG0537	adenosine 5'-monophosphoramidase activity
NO935_18720	COG0314	molybdopterin synthase activity
NO935_18725	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NO935_18730	COG0315	cyclic pyranopterin monophosphate synthase activity
NO935_18740	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NO935_18745	COG1234	tRNA 3'-trailer cleavage
NO935_18750	COG3642	lipopolysaccharide core region biosynthetic process
NO935_18755	COG0859	PFAM glycosyl transferase family 9
NO935_18765	COG0582	viral genome integration into host DNA
NO935_18825	COG0631	protein serine/threonine phosphatase activity
NO935_18860	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NO935_18900	COG0544	peptidyl-prolyl cis-trans isomerase activity
NO935_18950	COG0473	3-isopropylmalate dehydrogenase activity
NO935_18975	COG4783	chaperone-mediated protein folding
NO935_18990	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NO935_19000	COG0438	transferase activity, transferring glycosyl groups
NO935_19005	COG0671	phosphoesterase, PA-phosphatase related
NO935_19010	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NO935_19035	COG2833	Protein of unknown function (DUF455)
NO935_19055	COG0285	dihydrofolate synthase activity
NO935_19065	COG0406	alpha-ribazole phosphatase activity
NO935_19095	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NO935_19100	COG4208	sulfate ABC transporter
NO935_19105	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
NO935_19110	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
NO935_19115	COG0156	8-amino-7-oxononanoate synthase activity
NO935_19140	COG0604	alcohol dehydrogenase
NO935_19145	COG1902	pentaerythritol trinitrate reductase activity
NO935_19145	COG0446	pyridine nucleotide-disulphide oxidoreductase
NO935_19180	COG0584	glycerophosphoryl diester phosphodiesterase
NO935_19205	COG3039	Transposase
NO935_19220	COG0625	glutathione transferase activity
NO935_19225	COG0039	L-malate dehydrogenase activity
NO935_19230	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NO935_19235	COG1217	gtp-binding protein TYPA
NO935_19255	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
NO935_19400	COG3781	membrane
NO935_19410	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NO935_19440	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
NO935_19450	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NO935_19475	COG3710	Transcriptional regulator
NO935_19480	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NO935_19490	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NO935_19525	COG0066	3-isopropylmalate dehydratase activity
NO935_19530	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NO935_19560	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NO935_19565	COG1538	Outer membrane efflux protein
NO935_19570	COG1519	Transferase
NO935_19575	COG1560	Kdo2-lipid A biosynthetic process
NO935_19625	COG0308	aminopeptidase N
NO935_19630	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NO935_19640	COG0330	HflC and HflK could
NO935_19645	COG0330	HflC and HflK could
NO935_19665	COG0678	peroxiredoxin activity
NO935_19675	COG2826	transposase and inactivated derivatives, IS30 family
NO935_19770	COG3829	transcription factor binding
NO935_19805	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NO935_19810	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NO935_19820	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NO935_19825	COG1028	Short-chain dehydrogenase reductase Sdr
NO935_19850	COG1399	metal-binding, possibly nucleic acid-binding protein
NO935_19890	COG1518	maintenance of DNA repeat elements
NO935_19895	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NO935_19940	COG2188	Transcriptional regulator
NO935_19955	COG1450	Type ii and iii secretion system protein
NO935_19970	COG3166	PFAM Fimbrial assembly family protein
NO935_19975	COG3156	type II secretion system protein K
NO935_19980	COG4795	General secretion pathway protein
NO935_19985	COG2165	general secretion pathway protein
NO935_19990	COG4970	Tfp pilus assembly protein FimT
NO935_19995	COG2165	general secretion pathway protein
NO935_20000	COG1459	type II secretion system
NO935_20010	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NO935_20020	COG5295	Hep Hag repeat protein
NO935_20025	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NO935_20025	COG0047	phosphoribosylformylglycinamidine synthase activity
NO935_20030	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NO935_20035	COG4974	Belongs to the 'phage' integrase family
NO935_20050	COG0795	lipopolysaccharide-transporting ATPase activity
NO935_20060	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NO935_20075	COG0525	valine-tRNA ligase activity
NO935_20105	COG3039	Transposase
NO935_20130	COG3039	Transposase
NO935_20160	COG1183	phosphatidylcholine synthase activity
NO935_20170	COG0442	prolyl-tRNA aminoacylation
NO935_20185	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NO935_20190	COG1127	ABC transporter
NO935_20195	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NO935_20195	COG3218	ABC-type transport auxiliary lipoprotein component
NO935_20230	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NO935_20235	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
NO935_20235	COG0662	Cupin 2, conserved barrel domain protein
NO935_20260	COG2086	electron transfer activity
NO935_20285	COG3328	transposase activity
NO935_20325	COG0626	cystathionine gamma-synthase activity
NO935_20355	COG0625	glutathione transferase activity
NO935_20365	COG0513	Belongs to the DEAD box helicase family
NO935_20370	COG0720	synthase
NO935_20380	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NO935_20385	COG1956	GAF domain-containing protein
NO935_20420	COG0339	signal peptide processing
NO935_20470	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NO935_20475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NO935_20525	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NO935_20530	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NO935_20535	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NO935_20540	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NO935_20550	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NO935_20560	COG0356	it plays a direct role in the translocation of protons across the membrane
NO935_20580	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NO935_20590	COG0508	dehydrogenase complex catalyzes the overall conversion of
NO935_20620	COG2011	ABC-type metal ion transport system permease component
NO935_20630	COG0697	spore germination
NO935_20665	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NO935_20670	COG1187	pseudouridine synthase activity
NO935_20675	COG2813	Specifically methylates the guanine in position
NO935_20705	COG2205	protein histidine kinase activity
NO935_20705	COG2202	Pas domain
NO935_20730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NO935_20780	COG0745	RESPONSE REGULATOR receiver
NO935_20795	COG1404	Belongs to the peptidase S8 family
NO935_20815	COG0842	Transport permease protein
NO935_20820	COG1131	(ABC) transporter
NO935_20825	COG0025	NhaP-type Na H and K H
NO935_20835	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
NO935_20845	COG1573	uracil-dna glycosylase
NO935_20855	COG3384	dioxygenase
NO935_20870	COG0667	Aldo Keto reductase
NO935_20880	COG3590	peptidase
NO935_20900	COG0531	amino acid
NO935_20975	COG1271	oxidase subunit
NO935_20980	COG1294	oxidase, subunit
NO935_21010	COG1324	tolerance protein
NO935_21020	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NO935_21025	COG0511	ligase activity, forming carbon-carbon bonds
NO935_21035	COG0439	Biotin carboxylase
NO935_21075	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
NO935_21125	COG3039	Transposase
NO935_21145	COG3039	Transposase
NO935_21175	COG3210	domain, Protein
NO935_21180	COG2831	hemolysin activation secretion protein
NO935_21220	COG0138	bifunctional purine biosynthesis protein purh
NO935_21230	COG0151	Belongs to the GarS family
NO935_21235	COG0577	efflux transmembrane transporter activity
NO935_21235	COG1136	(ABC) transporter
NO935_21245	COG1289	transmembrane transporter activity
NO935_21260	COG2814	Major facilitator Superfamily
NO935_21275	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
NO935_21310	COG0745	RESPONSE REGULATOR receiver
NO935_21355	COG0739	heme binding
NO935_21370	COG2211	Major facilitator Superfamily
NO935_21375	COG0708	Exodeoxyribonuclease III
NO935_21390	COG1192	Involved in chromosome partitioning
NO935_21395	COG1475	DNA binding
NO935_21410	COG0463	Glycosyl transferase, family 2
NO935_21430	COG0756	dUTP diphosphatase activity
NO935_21435	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NO935_21440	COG2003	Belongs to the UPF0758 family
NO935_21445	COG0018	arginyl-trna synthetase
NO935_21460	COG4221	oxidoreductase activity
NO935_21485	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NO935_21490	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NO935_21510	COG3485	protocatechuate 3,4-dioxygenase
NO935_21550	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NO935_21555	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NO935_21565	COG0045	succinate-CoA ligase (ADP-forming) activity
NO935_21565	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NO935_21565	COG1042	CoA-binding domain protein
NO935_21575	COG2239	Acts as a magnesium transporter
NO935_21590	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NO935_21595	COG3387	PFAM Glycoside hydrolase 15-related
NO935_21610	COG3100	YcgL domain-containing protein
NO935_21615	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NO935_21625	COG0463	Glycosyl transferase, family 2
NO935_21640	COG1028	Short-chain dehydrogenase reductase Sdr
NO935_21650	COG0156	8-amino-7-oxononanoate synthase activity
NO935_21655	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NO935_21660	COG1040	competence protein
NO935_21665	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NO935_21675	COG0628	permease
NO935_21685	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NO935_21695	COG1595	DNA-templated transcription, initiation
NO935_21700	COG0753	catalase activity
NO935_21745	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NO935_21750	COG0180	Tryptophanyl-tRNA synthetase
NO935_21755	COG3237	CsbD-like
NO935_21790	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NO935_21810	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NO935_21815	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
NO935_21815	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
NO935_21860	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NO935_21900	COG1199	ATP-dependent helicase activity
NO935_21940	COG0583	DNA-binding transcription factor activity
NO935_21985	COG0625	glutathione transferase activity
NO935_22020	COG4555	ABC transporter
NO935_22030	COG1476	TRANSCRIPTIONal
NO935_22055	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NO935_22060	COG1131	(ABC) transporter
NO935_22065	COG0842	Transport permease protein
NO935_22075	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NO935_22140	COG1181	Belongs to the D-alanine--D-alanine ligase family
NO935_22150	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NO935_22160	COG0564	pseudouridine synthase activity
NO935_22190	COG0339	signal peptide processing
NO935_22220	COG3254	rhamnose metabolic process
NO935_22225	COG0738	Major facilitator superfamily
NO935_22230	COG1414	Transcriptional regulator
NO935_22245	COG2205	protein histidine kinase activity
NO935_22255	COG3459	Glycosyltransferase 36 associated
NO935_22260	COG2211	Major facilitator Superfamily
NO935_22265	COG3265	gluconokinase activity
NO935_22270	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NO935_22345	COG1127	ABC transporter
NO935_22350	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NO935_22355	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NO935_22370	COG2853	Lipoprotein
NO935_22390	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NO935_22455	COG0676	glucose-6-phosphate 1-epimerase activity
NO935_22480	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NO935_22490	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NO935_22500	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NO935_22505	COG1064	alcohol dehydrogenase
NO935_22545	COG1522	sequence-specific DNA binding
NO935_22550	COG3186	Phenylalanine-4-hydroxylase
NO935_22590	COG0656	L-ascorbic acid biosynthetic process
NO935_22595	COG2130	NADP-dependent
NO935_22600	COG0667	Aldo Keto reductase
NO935_22610	COG1187	pseudouridine synthase activity
NO935_22620	COG1643	Atp-dependent helicase
NO935_22625	COG4807	Protein conserved in bacteria
NO935_22630	COG4948	Mandelate Racemase Muconate Lactonizing
NO935_22635	COG0179	Fumarylacetoacetate (FAA) hydrolase
NO935_22640	COG1028	Short-chain dehydrogenase reductase Sdr
NO935_22700	COG3162	membrane
NO935_22705	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NO935_22720	COG0708	Exodeoxyribonuclease III
NO935_22730	COG3039	Transposase
NO935_22740	COG2091	lysine biosynthetic process via aminoadipic acid
NO935_22750	COG3540	Alkaline phosphatase
NO935_22755	COG0357	Ribosomal RNA small subunit methyltransferase G
NO935_22775	COG2159	amidohydrolase
NO935_22785	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NO935_22790	COG0583	DNA-binding transcription factor activity
NO935_22795	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NO935_22810	COG0210	DNA helicase
NO935_22825	COG0531	amino acid
NO935_22835	COG1322	Protein conserved in bacteria
NO935_22845	COG0386	Belongs to the glutathione peroxidase family
NO935_22895	COG0793	Belongs to the peptidase S41A family
NO935_22900	COG4942	peptidase
NO935_22910	COG2234	aminopeptidase activity
NO935_22955	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NO935_22960	COG0302	gtp cyclohydrolase
NO935_22980	COG0477	Major facilitator Superfamily
NO935_23065	COG1192	Involved in chromosome partitioning
NO935_23095	COG1929	Belongs to the glycerate kinase type-1 family
NO935_23100	COG2271	Major facilitator Superfamily
NO935_23115	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NO935_23120	COG0861	Integral membrane protein TerC family
NO935_23130	COG0584	glycerophosphoryl diester phosphodiesterase
NO935_23140	COG0671	phosphoesterase, PA-phosphatase related
NO935_23150	COG0726	polysaccharide deacetylase
NO935_23190	COG4720	Psort location CytoplasmicMembrane, score
NO935_23205	COG0110	maltose O-acetyltransferase activity
NO935_23215	COG0308	aminopeptidase N
NO935_23240	COG2186	Transcriptional regulator
NO935_23270	COG2814	Major facilitator Superfamily
NO935_23275	COG2814	Major facilitator Superfamily
NO935_23350	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NO935_23375	COG4974	Belongs to the 'phage' integrase family
NO935_23640	COG1061	Type III restriction enzyme res subunit
NO935_23700	COG0582	viral genome integration into host DNA
NO935_23710	COG2261	transglycosylase associated protein
NO935_23725	COG0446	pyridine nucleotide-disulphide oxidoreductase
NO935_23730	COG2826	transposase and inactivated derivatives, IS30 family
NO935_23770	COG1192	Involved in chromosome partitioning
NO935_23785	COG1278	Cold shock
NO935_23815	COG0577	efflux transmembrane transporter activity
NO935_23815	COG1136	(ABC) transporter
NO935_23825	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NO935_23850	COG1192	Involved in chromosome partitioning
NO935_23860	COG2189	Belongs to the N(4) N(6)-methyltransferase family
NO935_23865	COG3421	Type III restriction