locus-tag	class	description
ACU12_00020	COG0187	DNA topoisomerase II activity
ACU12_00030	COG0501	Belongs to the peptidase M48B family
ACU12_00060	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ACU12_00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ACU12_00075	COG3039	Transposase
ACU12_00090	COG1064	alcohol dehydrogenase
ACU12_00095	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ACU12_00100	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ACU12_00105	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ACU12_00115	COG2234	aminopeptidase activity
ACU12_00125	COG4942	peptidase
ACU12_00130	COG0793	Belongs to the peptidase S41A family
ACU12_00135	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ACU12_00200	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
ACU12_00215	COG0210	DNA helicase
ACU12_00235	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
ACU12_00270	COG2937	Belongs to the GPAT DAPAT family
ACU12_00305	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ACU12_00330	COG2351	hydroxyisourate hydrolase activity
ACU12_00335	COG4807	Protein conserved in bacteria
ACU12_00345	COG1643	Atp-dependent helicase
ACU12_00355	COG1187	pseudouridine synthase activity
ACU12_00365	COG0667	Aldo Keto reductase
ACU12_00370	COG2130	NADP-dependent
ACU12_00375	COG0656	L-ascorbic acid biosynthetic process
ACU12_00390	COG3293	Transposase
ACU12_00410	COG1764	response to oxidative stress
ACU12_00415	COG1846	Transcriptional regulator
ACU12_00420	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ACU12_00440	COG0523	cobalamin synthesis protein
ACU12_00485	COG1960	acyl-CoA dehydrogenase activity
ACU12_00490	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ACU12_00530	COG3693	PFAM glycoside hydrolase, family 10
ACU12_00535	COG3693	PFAM glycoside hydrolase, family 10
ACU12_00555	COG2211	Major facilitator Superfamily
ACU12_00585	COG2826	transposase and inactivated derivatives, IS30 family
ACU12_00600	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ACU12_00670	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ACU12_00675	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ACU12_00685	COG3485	protocatechuate 3,4-dioxygenase
ACU12_00690	COG3485	protocatechuate 3,4-dioxygenase
ACU12_00700	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACU12_00705	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ACU12_00715	COG1414	Transcriptional regulator
ACU12_00845	COG1040	competence protein
ACU12_00850	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ACU12_00875	COG2911	Protein conserved in bacteria
ACU12_00880	COG0729	surface antigen
ACU12_00895	COG0457	Tetratricopeptide repeat
ACU12_00905	COG0752	glycyl-tRNA synthetase alpha subunit
ACU12_00910	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ACU12_00920	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ACU12_00920	COG0519	Catalyzes the synthesis of GMP from XMP
ACU12_00930	COG0805	protein transport
ACU12_00935	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ACU12_00940	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ACU12_00950	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ACU12_00970	COG2974	May be involved in recombination
ACU12_00990	COG3661	Belongs to the glycosyl hydrolase 67 family
ACU12_01000	COG4948	Mandelate Racemase Muconate Lactonizing
ACU12_01010	COG1472	Belongs to the glycosyl hydrolase 3 family
ACU12_01015	COG0246	Mannitol dehydrogenase
ACU12_01115	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ACU12_01185	COG1511	domain protein
ACU12_01185	COG3264	Mechanosensitive ion channel
ACU12_01200	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ACU12_01205	COG2354	Protein conserved in bacteria
ACU12_01215	COG3706	GGDEF domain
ACU12_01215	COG0745	RESPONSE REGULATOR receiver
ACU12_01230	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ACU12_01255	COG0702	epimerase
ACU12_01265	COG2826	transposase and inactivated derivatives, IS30 family
ACU12_01275	COG3039	Transposase
ACU12_01315	COG2801	Transposase and inactivated derivatives
ACU12_01360	COG2801	Transposase and inactivated derivatives
ACU12_01365	COG2963	transposase activity
ACU12_01405	COG0084	hydrolase, TatD family'
ACU12_01415	COG0583	DNA-binding transcription factor activity
ACU12_01420	COG2814	Major facilitator Superfamily
ACU12_01430	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ACU12_01455	COG0745	RESPONSE REGULATOR receiver
ACU12_01460	COG2205	protein histidine kinase activity
ACU12_01465	COG2205	protein histidine kinase activity
ACU12_01475	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ACU12_01480	COG0583	DNA-binding transcription factor activity
ACU12_01505	COG1733	regulation of RNA biosynthetic process
ACU12_01510	COG0702	epimerase
ACU12_01580	COG1199	ATP-dependent helicase activity
ACU12_01620	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ACU12_01630	COG0745	RESPONSE REGULATOR receiver
ACU12_01635	COG2205	protein histidine kinase activity
ACU12_01650	COG3228	Belongs to the MtfA family
ACU12_01710	COG3237	CsbD-like
ACU12_01715	COG0180	Tryptophanyl-tRNA synthetase
ACU12_01720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACU12_01760	COG0753	catalase activity
ACU12_01775	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ACU12_01805	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACU12_01815	COG0642	Histidine kinase
ACU12_01820	COG1090	epimerase
ACU12_01865	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ACU12_01875	COG0606	chelatase, subunit chli
ACU12_01930	COG2963	transposase activity
ACU12_01960	COG1166	arginine decarboxylase activity
ACU12_01965	COG3039	Transposase
ACU12_01975	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ACU12_01975	COG2755	lipolytic protein G-D-S-L family
ACU12_01980	COG4221	oxidoreductase activity
ACU12_02005	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ACU12_02030	COG0463	Glycosyl transferase, family 2
ACU12_02045	COG1475	DNA binding
ACU12_02050	COG1192	Involved in chromosome partitioning
ACU12_02075	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ACU12_02085	COG0456	acetyltransferase
ACU12_02130	COG0134	indole-3-glycerol-phosphate synthase activity
ACU12_02140	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ACU12_02160	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ACU12_02235	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
ACU12_02250	COG2814	Major facilitator Superfamily
ACU12_02265	COG1289	transmembrane transporter activity
ACU12_02275	COG1136	(ABC) transporter
ACU12_02275	COG0577	efflux transmembrane transporter activity
ACU12_02280	COG0151	Belongs to the GarS family
ACU12_02285	COG0138	bifunctional purine biosynthesis protein purh
ACU12_02300	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
ACU12_02335	COG0439	Biotin carboxylase
ACU12_02345	COG0511	ligase activity, forming carbon-carbon bonds
ACU12_02365	COG1324	tolerance protein
ACU12_02370	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ACU12_02390	COG0534	Mate efflux family protein
ACU12_02395	COG0616	signal peptide processing
ACU12_02405	COG1028	Short-chain dehydrogenase reductase Sdr
ACU12_02425	COG1754	DNA topoisomerase type I activity
ACU12_02425	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ACU12_02445	COG0758	DNA mediated transformation
ACU12_02450	COG1652	LysM domain
ACU12_02455	COG0242	peptide deformylase activity
ACU12_02465	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ACU12_02465	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ACU12_02510	COG1560	Kdo2-lipid A biosynthetic process
ACU12_02520	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ACU12_02550	COG0625	glutathione transferase activity
ACU12_02585	COG4555	ABC transporter
ACU12_02595	COG1476	TRANSCRIPTIONal
ACU12_02615	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ACU12_02620	COG1131	(ABC) transporter
ACU12_02625	COG0842	Transport permease protein
ACU12_02635	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ACU12_02660	COG3039	Transposase
ACU12_02700	COG0577	efflux transmembrane transporter activity
ACU12_02715	COG2963	transposase activity
ACU12_02720	COG2951	lytic endotransglycosylase activity
ACU12_02750	COG3039	Transposase
ACU12_02765	COG3209	COG3209 Rhs family protein
ACU12_02775	COG2801	Transposase and inactivated derivatives
ACU12_02790	COG2831	hemolysin activation secretion protein
ACU12_02865	COG2963	transposase activity
ACU12_02880	COG4221	oxidoreductase activity
ACU12_02925	COG0697	spore germination
ACU12_02930	COG4305	rare lipoprotein A
ACU12_02955	COG1113	amino acid transport
ACU12_02965	COG0598	Magnesium transport protein CorA
ACU12_03035	COG0659	secondary active sulfate transmembrane transporter activity
ACU12_03060	COG3275	phosphorelay sensor kinase activity
ACU12_03095	COG1505	serine-type exopeptidase activity
ACU12_03115	COG2832	Protein of unknown function (DUF454)
ACU12_03135	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ACU12_03180	COG3300	MHYT domain
ACU12_03180	COG5001	Diguanylate cyclase
ACU12_03205	COG1077	Cell shape determining protein MreB Mrl
ACU12_03210	COG1792	Involved in formation and maintenance of cell shape
ACU12_03225	COG0772	Belongs to the SEDS family
ACU12_03235	COG3501	Rhs element vgr protein
ACU12_03245	COG2826	transposase and inactivated derivatives, IS30 family
ACU12_03265	COG2951	lytic endotransglycosylase activity
ACU12_03270	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ACU12_03280	COG1686	Belongs to the peptidase S11 family
ACU12_03315	COG1051	belongs to the nudix hydrolase family
ACU12_03315	COG1056	cytidyltransferase-related domain
ACU12_03355	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
ACU12_03360	COG0673	inositol 2-dehydrogenase activity
ACU12_03365	COG2823	Periplasmic or secreted lipoprotein
ACU12_03370	COG4251	negative regulation of phosphorylation
ACU12_03375	COG0784	Response regulator, receiver
ACU12_03380	COG4191	Histidine kinase
ACU12_03385	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ACU12_03415	COG3250	beta-galactosidase activity
ACU12_03440	COG1609	Transcriptional regulator
ACU12_03445	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ACU12_03450	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ACU12_03460	COG1215	transferase activity, transferring glycosyl groups
ACU12_03465	COG1649	PFAM Uncharacterised BCR, COG1649
ACU12_03465	COG0726	polysaccharide deacetylase
ACU12_03475	COG2826	transposase and inactivated derivatives, IS30 family
ACU12_03490	COG1012	belongs to the aldehyde dehydrogenase family
ACU12_03560	COG3039	Transposase
ACU12_03575	COG2205	protein histidine kinase activity
ACU12_03580	COG0745	RESPONSE REGULATOR receiver
ACU12_03620	COG0488	(ABC) transporter
ACU12_03650	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ACU12_03660	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACU12_03660	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACU12_03665	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACU12_03665	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACU12_03695	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ACU12_03715	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ACU12_03720	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ACU12_03730	COG2205	protein histidine kinase activity
ACU12_03735	COG0745	RESPONSE REGULATOR receiver
ACU12_03740	COG0277	FAD linked oxidase domain protein
ACU12_03745	COG1988	membrane-bound metal-dependent
ACU12_03790	COG3116	cell division
ACU12_03805	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ACU12_03810	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ACU12_03830	COG1181	Belongs to the D-alanine--D-alanine ligase family
ACU12_03835	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ACU12_03860	COG1388	LysM domain
ACU12_03860	COG4942	peptidase
ACU12_03875	COG0494	nUDIX hydrolase
ACU12_03885	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ACU12_03895	COG3321	synthase
ACU12_03895	COG1028	Short-chain dehydrogenase reductase Sdr
ACU12_03895	COG0604	alcohol dehydrogenase
ACU12_03945	COG2226	methyltransferase
ACU12_03990	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ACU12_04005	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ACU12_04020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACU12_04025	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ACU12_04040	COG0667	Aldo Keto reductase
ACU12_04075	COG2175	clavaminate synthase activity
ACU12_04085	COG4181	ATPase activity
ACU12_04100	COG0642	Histidine kinase
ACU12_04110	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ACU12_04150	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ACU12_04165	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ACU12_04180	COG0123	including yeast histone deacetylase and acetoin utilization protein
ACU12_04185	COG2096	Adenosyltransferase
ACU12_04195	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACU12_04200	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACU12_04230	COG3384	dioxygenase
ACU12_04235	COG0583	DNA-binding transcription factor activity
ACU12_04240	COG0318	PFAM AMP-dependent synthetase and ligase
ACU12_04250	COG1024	Enoyl-CoA hydratase
ACU12_04270	COG3386	PFAM SMP-30 Gluconolaconase
ACU12_04295	COG0697	spore germination
ACU12_04320	COG3706	GGDEF domain
ACU12_04320	COG0745	RESPONSE REGULATOR receiver
ACU12_04325	COG2197	response regulator
ACU12_04335	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ACU12_04340	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ACU12_04350	COG0583	DNA-binding transcription factor activity
ACU12_04355	COG3634	alkyl hydroperoxide reductase activity
ACU12_04365	COG2890	protein-(glutamine-N5) methyltransferase activity
ACU12_04410	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ACU12_04435	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ACU12_04440	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ACU12_04460	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ACU12_04465	COG1404	Belongs to the peptidase S8 family
ACU12_04470	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ACU12_04505	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ACU12_04525	COG0521	Mo-molybdopterin cofactor biosynthetic process
ACU12_04540	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ACU12_04565	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ACU12_04580	COG0012	GTP binding
ACU12_04610	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ACU12_04615	COG0250	Participates in transcription elongation, termination and antitermination
ACU12_04625	COG0081	regulation of translation
ACU12_04630	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ACU12_04650	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ACU12_04690	COG0089	rRNA binding
ACU12_04695	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ACU12_04715	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ACU12_04720	COG0255	Belongs to the universal ribosomal protein uL29 family
ACU12_04725	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ACU12_04735	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ACU12_04745	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ACU12_04765	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ACU12_04770	COG1841	ribosomal large subunit assembly
ACU12_04775	COG0200	Binds to the 23S rRNA
ACU12_04780	COG0201	protein transport
ACU12_04785	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ACU12_04800	COG0202	RNA polymerase activity
ACU12_04805	COG0203	ribosomal protein L17
ACU12_04810	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ACU12_04820	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ACU12_04845	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ACU12_04875	COG0584	glycerophosphoryl diester phosphodiesterase
ACU12_04895	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACU12_04895	COG1902	pentaerythritol trinitrate reductase activity
ACU12_04900	COG0604	alcohol dehydrogenase
ACU12_04925	COG0156	8-amino-7-oxononanoate synthase activity
ACU12_04930	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ACU12_04935	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ACU12_04940	COG4208	sulfate ABC transporter
ACU12_04945	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ACU12_04955	COG1063	alcohol dehydrogenase
ACU12_04980	COG0406	alpha-ribazole phosphatase activity
ACU12_04985	COG0285	dihydrofolate synthase activity
ACU12_05005	COG2833	Protein of unknown function (DUF455)
ACU12_05030	COG0671	phosphoesterase, PA-phosphatase related
ACU12_05035	COG0438	transferase activity, transferring glycosyl groups
ACU12_05045	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ACU12_05060	COG4783	chaperone-mediated protein folding
ACU12_05075	COG0473	3-isopropylmalate dehydrogenase activity
ACU12_05110	COG2963	transposase activity
ACU12_05125	COG0544	peptidyl-prolyl cis-trans isomerase activity
ACU12_05130	COG0740	serine-type endopeptidase activity
ACU12_05165	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ACU12_05190	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ACU12_05195	COG0631	protein serine/threonine phosphatase activity
ACU12_05210	COG0859	PFAM glycosyl transferase family 9
ACU12_05220	COG1234	tRNA 3'-trailer cleavage
ACU12_05225	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ACU12_05240	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ACU12_05245	COG0314	molybdopterin synthase activity
ACU12_05260	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ACU12_05270	COG0537	adenosine 5'-monophosphoramidase activity
ACU12_05290	COG0714	Associated with various cellular activities
ACU12_05310	COG1399	metal-binding, possibly nucleic acid-binding protein
ACU12_05335	COG1028	Short-chain dehydrogenase reductase Sdr
ACU12_05350	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ACU12_05355	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ACU12_05385	COG3829	transcription factor binding
ACU12_05400	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ACU12_05445	COG0678	peroxiredoxin activity
ACU12_05465	COG0330	HflC and HflK could
ACU12_05470	COG0330	HflC and HflK could
ACU12_05485	COG0308	aminopeptidase N
ACU12_05495	COG1028	Short-chain dehydrogenase reductase Sdr
ACU12_05500	COG3501	Rhs element vgr protein
ACU12_05550	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
ACU12_05620	COG0406	alpha-ribazole phosphatase activity
ACU12_05620	COG0328	RNA-DNA hybrid ribonuclease activity
ACU12_05625	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ACU12_05660	COG0587	DNA-directed DNA polymerase activity
ACU12_05675	COG1297	OPT oligopeptide transporter protein
ACU12_05685	COG0823	Involved in the tonB-independent uptake of proteins
ACU12_05685	COG1506	peptidase
ACU12_05695	COG1917	Cupin 2, conserved barrel domain protein
ACU12_05695	COG2207	Transcriptional regulator
ACU12_05715	COG0753	catalase activity
ACU12_05750	COG3551	Protein conserved in bacteria
ACU12_05785	COG2194	sulfuric ester hydrolase activity
ACU12_05795	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ACU12_05800	COG0745	RESPONSE REGULATOR receiver
ACU12_05805	COG0642	Histidine kinase
ACU12_05815	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ACU12_05820	COG2894	cell division
ACU12_05835	COG4585	Histidine kinase
ACU12_05840	COG2197	response regulator
ACU12_05855	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ACU12_05885	COG2963	transposase activity
ACU12_05940	COG3501	Rhs element vgr protein
ACU12_05955	COG3501	Rhs element vgr protein
ACU12_06005	COG3501	Rhs element vgr protein
ACU12_06010	COG2801	Transposase and inactivated derivatives
ACU12_06015	COG2963	transposase activity
ACU12_06030	COG3501	Rhs element vgr protein
ACU12_06055	COG3501	Rhs element vgr protein
ACU12_06120	COG3501	Rhs element vgr protein
ACU12_06145	COG3039	Transposase
ACU12_06210	COG1842	Phage shock protein A
ACU12_06235	COG0754	glutathionylspermidine amidase activity
ACU12_06265	COG0789	Transcriptional regulator
ACU12_06305	COG3039	Transposase
ACU12_06320	COG0531	amino acid
ACU12_06325	COG2197	response regulator
ACU12_06335	COG1113	amino acid transport
ACU12_06340	COG1271	oxidase subunit
ACU12_06345	COG1294	oxidase, subunit
ACU12_06355	COG2239	Acts as a magnesium transporter
ACU12_06360	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ACU12_06365	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACU12_06385	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACU12_06400	COG1137	ATPase activity
ACU12_06405	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ACU12_06415	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ACU12_06425	COG0271	Belongs to the BolA IbaG family
ACU12_06430	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ACU12_06450	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ACU12_06475	COG0628	permease
ACU12_06485	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ACU12_06490	COG3178	'Phosphotransferase
ACU12_06510	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ACU12_06515	COG1555	photosystem II stabilization
ACU12_06545	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ACU12_06550	COG0719	Fe-S assembly protein
ACU12_06555	COG0396	ATPase activity
ACU12_06560	COG0719	Fe-S assembly protein
ACU12_06565	COG1959	2 iron, 2 sulfur cluster binding
ACU12_06615	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ACU12_06640	COG0519	Catalyzes the synthesis of GMP from XMP
ACU12_06655	COG1678	Uncharacterized ACR, COG1678
ACU12_06665	COG0540	Belongs to the ATCase OTCase family
ACU12_06670	COG1764	response to oxidative stress
ACU12_06680	COG0384	phenazine biosynthesis protein PhzF
ACU12_06690	COG0527	aspartate kinase activity
ACU12_06730	COG0142	geranyltranstransferase activity
ACU12_06735	COG0629	single-stranded DNA binding
ACU12_06740	COG2203	Gaf domain
ACU12_06740	COG4251	negative regulation of phosphorylation
ACU12_06740	COG3706	GGDEF domain
ACU12_06740	COG5001	Diguanylate cyclase
ACU12_06745	COG3321	synthase
ACU12_06745	COG1028	Short-chain dehydrogenase reductase Sdr
ACU12_06745	COG0604	alcohol dehydrogenase
ACU12_06755	COG2080	2 iron, 2 sulfur cluster binding
ACU12_06760	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ACU12_06765	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ACU12_06770	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ACU12_06795	COG2879	small protein
ACU12_06800	COG1966	Carbon starvation protein
ACU12_06805	COG1741	Belongs to the pirin family
ACU12_06815	COG3501	Rhs element vgr protein
ACU12_06850	COG3501	Rhs element vgr protein
ACU12_06895	COG1741	Belongs to the pirin family
ACU12_06905	COG1515	deoxyribonuclease V activity
ACU12_06915	COG2801	Transposase and inactivated derivatives
ACU12_06920	COG2963	transposase activity
ACU12_06930	COG3501	Rhs element vgr protein
ACU12_06970	COG2801	Transposase and inactivated derivatives
ACU12_06995	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ACU12_07000	COG2202	Pas domain
ACU12_07000	COG2199	diguanylate cyclase activity
ACU12_07000	COG2200	EAL domain
ACU12_07005	COG0835	chemotaxis
ACU12_07010	COG0840	transmembrane signaling receptor activity
ACU12_07015	COG2198	Histidine kinase
ACU12_07015	COG0643	Histidine kinase
ACU12_07025	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ACU12_07035	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ACU12_07075	COG0735	belongs to the Fur family
ACU12_07195	COG5001	Diguanylate cyclase
ACU12_07195	COG5002	protein histidine kinase activity
ACU12_07200	COG1187	pseudouridine synthase activity
ACU12_07220	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ACU12_07225	COG0475	glutathione-regulated potassium exporter activity
ACU12_07230	COG5002	protein histidine kinase activity
ACU12_07230	COG5000	phosphorelay sensor kinase activity
ACU12_07235	COG0745	RESPONSE REGULATOR receiver
ACU12_07265	COG1132	(ABC) transporter
ACU12_07285	COG2826	transposase and inactivated derivatives, IS30 family
ACU12_07325	COG3118	belongs to the thioredoxin family
ACU12_07350	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ACU12_07385	COG2968	Membrane
ACU12_07395	COG1530	ribonuclease E activity
ACU12_07400	COG3164	Protein of unknown function
ACU12_07410	COG0312	modulator of DNA gyrase
ACU12_07415	COG3028	Belongs to the UPF0307 family
ACU12_07420	COG0312	modulator of DNA gyrase
ACU12_07445	COG4104	PAAR repeat-containing protein
ACU12_07450	COG0142	geranyltranstransferase activity
ACU12_07455	COG1722	exodeoxyribonuclease VII activity
ACU12_07460	COG0037	tRNA processing
ACU12_07465	COG1785	Belongs to the alkaline phosphatase family
ACU12_07470	COG1301	dicarboxylic acid transport
ACU12_07475	COG4106	trans-aconitate 2-methyltransferase activity
ACU12_07490	COG0791	NLP P60 protein
ACU12_07495	COG0791	NLP P60 protein
ACU12_07500	COG1047	Peptidyl-prolyl cis-trans
ACU12_07505	COG2311	Membrane
ACU12_07510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACU12_07530	COG2963	transposase activity
ACU12_07535	COG2801	Transposase and inactivated derivatives
ACU12_07555	COG3501	Rhs element vgr protein
ACU12_07620	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ACU12_07630	COG2914	Belongs to the UPF0125 (RnfH) family
ACU12_07635	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACU12_07645	COG0497	DNA recombination
ACU12_07660	COG0443	Heat shock 70 kDa protein
ACU12_07670	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
ACU12_07685	COG0583	DNA-binding transcription factor activity
ACU12_07690	COG1132	(ABC) transporter
ACU12_07725	COG2850	peptidyl-arginine hydroxylation
ACU12_07785	COG1131	(ABC) transporter
ACU12_07790	COG1725	Transcriptional regulator
ACU12_07800	COG0386	Belongs to the glutathione peroxidase family
ACU12_07840	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACU12_07865	COG1960	acyl-CoA dehydrogenase activity
ACU12_07885	COG0557	exoribonuclease II activity
ACU12_07895	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACU12_07900	COG3706	GGDEF domain
ACU12_07905	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ACU12_07915	COG0704	Plays a role in the regulation of phosphate uptake
ACU12_07930	COG0573	inorganic phosphate transmembrane transporter activity
ACU12_07935	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ACU12_07960	COG0659	secondary active sulfate transmembrane transporter activity
ACU12_07965	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ACU12_07975	COG1024	Enoyl-CoA hydratase
ACU12_07985	COG0494	nUDIX hydrolase
ACU12_08035	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ACU12_08050	COG0667	Aldo Keto reductase
ACU12_08060	COG2925	Exonuclease
ACU12_08070	COG3844	kynureninase activity
ACU12_08085	COG0288	reversible hydration of carbon dioxide
ACU12_08115	COG0316	Belongs to the HesB IscA family
ACU12_08140	COG3115	cell septum assembly
ACU12_08155	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
ACU12_08210	COG3039	Transposase
ACU12_08225	COG0583	DNA-binding transcription factor activity
ACU12_08260	COG3039	Transposase
ACU12_08270	COG2826	transposase and inactivated derivatives, IS30 family
ACU12_08290	COG2801	Transposase and inactivated derivatives
ACU12_08300	COG0840	transmembrane signaling receptor activity
ACU12_08315	COG3039	Transposase
ACU12_08340	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ACU12_08360	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ACU12_08375	COG1595	DNA-templated transcription, initiation
ACU12_08425	COG2244	polysaccharide biosynthetic process
ACU12_08455	COG2264	protein methyltransferase activity
ACU12_08465	COG0438	transferase activity, transferring glycosyl groups
ACU12_08480	COG1136	(ABC) transporter
ACU12_08485	COG1132	(ABC) transporter
ACU12_08490	COG2271	Major facilitator Superfamily
ACU12_08495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACU12_08510	COG1253	flavin adenine dinucleotide binding
ACU12_08560	COG0148	phosphopyruvate hydratase activity
ACU12_08585	COG2840	Smr protein MutS2
ACU12_08600	COG1238	metal cluster binding
ACU12_08610	COG3737	Protein of unknown function (DUF498/DUF598)
ACU12_08615	COG1534	Rna-binding protein
ACU12_08625	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACU12_08630	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ACU12_08640	COG1923	regulation of RNA biosynthetic process
ACU12_08645	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ACU12_08650	COG1546	Belongs to the CinA family
ACU12_08670	COG2137	regulation of response to DNA damage stimulus
ACU12_08680	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ACU12_08700	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ACU12_08720	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ACU12_08735	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ACU12_08750	COG2166	iron-sulfur cluster assembly
ACU12_08765	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ACU12_08770	COG0137	argininosuccinate synthase activity
ACU12_08780	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ACU12_08785	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ACU12_08845	COG1294	oxidase, subunit
ACU12_08850	COG1271	oxidase subunit
ACU12_08860	COG4988	ABC transporter
ACU12_08865	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ACU12_08920	COG4133	protoheme IX ABC transporter activity
ACU12_08925	COG0436	Aminotransferase
ACU12_08945	COG1187	pseudouridine synthase activity
ACU12_08950	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ACU12_08955	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ACU12_08960	COG2350	Protein conserved in bacteria
ACU12_08990	COG1175	transmembrane transport
ACU12_08995	COG0395	ABC-type sugar transport system, permease component
ACU12_09015	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ACU12_09020	COG2957	Belongs to the agmatine deiminase family
ACU12_09030	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ACU12_09035	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ACU12_09040	COG0539	negative regulation of cytoplasmic translation
ACU12_09055	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ACU12_09060	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ACU12_09070	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ACU12_09075	COG0475	glutathione-regulated potassium exporter activity
ACU12_09075	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ACU12_09100	COG0519	Catalyzes the synthesis of GMP from XMP
ACU12_09100	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ACU12_09110	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ACU12_09115	COG0583	DNA-binding transcription factor activity
ACU12_09135	COG0583	DNA-binding transcription factor activity
ACU12_09140	COG0583	DNA-binding transcription factor activity
ACU12_09160	COG1914	H( )-stimulated, divalent metal cation uptake system
ACU12_09165	COG1321	iron dependent repressor
ACU12_09170	COG0590	tRNA wobble adenosine to inosine editing
ACU12_09180	COG0668	transmembrane transport
ACU12_09205	COG1028	Short-chain dehydrogenase reductase Sdr
ACU12_09210	COG1183	phosphatidylcholine synthase activity
ACU12_09220	COG3243	poly(R)-hydroxyalkanoic acid synthase
ACU12_09235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACU12_09235	COG0723	plastoquinol--plastocyanin reductase activity
ACU12_09245	COG2183	response to ionizing radiation
ACU12_09250	COG2205	protein histidine kinase activity
ACU12_09250	COG0784	Response regulator, receiver
ACU12_09360	COG2826	transposase and inactivated derivatives, IS30 family
ACU12_09375	COG0800	Aldolase
ACU12_09380	COG0129	dihydroxy-acid dehydratase activity
ACU12_09385	COG0363	glucosamine-6-phosphate deaminase activity
ACU12_09395	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ACU12_09405	COG0354	folic acid binding
ACU12_09415	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ACU12_09430	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ACU12_09445	COG4591	ABC-type transport system involved in lipoprotein release permease component
ACU12_09470	COG0811	peptide transport
ACU12_09495	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ACU12_09555	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACU12_09570	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ACU12_09600	COG1530	ribonuclease E activity
ACU12_09625	COG2154	pterin-4-alpha-carbinolamine dehydratase
ACU12_09640	COG2963	transposase activity
ACU12_09675	COG3501	Rhs element vgr protein
ACU12_09725	COG3039	Transposase
ACU12_09735	COG3501	Rhs element vgr protein
ACU12_09770	COG0631	protein serine/threonine phosphatase activity
ACU12_09775	COG0515	serine threonine protein kinase
ACU12_09800	COG1858	cytochrome C peroxidase
ACU12_09830	COG2963	transposase activity
ACU12_09860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACU12_09865	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACU12_09955	COG3039	Transposase
ACU12_09965	COG2826	transposase and inactivated derivatives, IS30 family
ACU12_10025	COG2801	Transposase and inactivated derivatives
ACU12_10030	COG2963	transposase activity
ACU12_10035	COG2201	protein-glutamate methylesterase activity
ACU12_10050	COG3039	Transposase
ACU12_10080	COG4566	intracellular signal transduction
ACU12_10095	COG5001	Diguanylate cyclase
ACU12_10140	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ACU12_10140	COG1648	precorrin-2 dehydrogenase activity
ACU12_10165	COG0746	molybdenum cofactor guanylyltransferase activity
ACU12_10205	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ACU12_10215	COG0303	'Molybdopterin
ACU12_10220	COG1160	GTP binding
ACU12_10225	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACU12_10250	COG0105	UTP biosynthetic process
ACU12_10260	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACU12_10260	COG1024	Enoyl-CoA hydratase
ACU12_10265	COG0183	Belongs to the thiolase family
ACU12_10270	COG0038	chloride channel
ACU12_10290	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ACU12_10310	COG1674	ftsk spoiiie
ACU12_10315	COG0492	ferredoxin-NADP+ reductase activity
ACU12_10340	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ACU12_10345	COG0542	response to heat
ACU12_10350	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ACU12_10360	COG0482	sulfurtransferase activity
ACU12_10390	COG4585	Histidine kinase
ACU12_10400	COG4191	Histidine kinase
ACU12_10420	COG0835	chemotaxis
ACU12_10420	COG0784	Response regulator, receiver
ACU12_10430	COG1558	bacterial-type flagellum-dependent cell motility
ACU12_10435	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ACU12_10440	COG1749	Flagellar hook protein flgE
ACU12_10445	COG4787	bacterial-type flagellum-dependent cell motility
ACU12_10450	COG4786	Flagellar basal body rod
ACU12_10480	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ACU12_10485	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ACU12_10515	COG2201	protein-glutamate methylesterase activity
ACU12_10520	COG2204	response regulator
ACU12_10535	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ACU12_10540	COG4221	oxidoreductase activity
ACU12_10545	COG1028	Short-chain dehydrogenase reductase Sdr
ACU12_10575	COG1677	Flagellar hook-basal body complex protein FliE
ACU12_10625	COG3190	flagellar
ACU12_10635	COG1987	bacterial-type flagellum assembly
ACU12_10640	COG1684	flagellar biosynthetic protein fliR
ACU12_10645	COG5001	Diguanylate cyclase
ACU12_10645	COG3300	MHYT domain
ACU12_10650	COG3300	MHYT domain
ACU12_10650	COG5001	Diguanylate cyclase
ACU12_10675	COG0455	bacterial-type flagellum organization
ACU12_10695	COG0643	Histidine kinase
ACU12_10695	COG2198	Histidine kinase
ACU12_10750	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ACU12_10770	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ACU12_10775	COG1360	Flagellar Motor Protein
ACU12_10780	COG1192	Involved in chromosome partitioning
ACU12_10785	COG0835	chemotaxis
ACU12_10795	COG0745	RESPONSE REGULATOR receiver
ACU12_10805	COG0840	transmembrane signaling receptor activity
ACU12_10815	COG0840	transmembrane signaling receptor activity
ACU12_10820	COG0840	transmembrane signaling receptor activity
ACU12_10830	COG0840	transmembrane signaling receptor activity
ACU12_10835	COG0840	transmembrane signaling receptor activity
ACU12_10840	COG0840	transmembrane signaling receptor activity
ACU12_10845	COG0840	transmembrane signaling receptor activity
ACU12_10850	COG0840	transmembrane signaling receptor activity
ACU12_10855	COG0840	transmembrane signaling receptor activity
ACU12_10860	COG0840	transmembrane signaling receptor activity
ACU12_10865	COG0840	transmembrane signaling receptor activity
ACU12_10875	COG0835	chemotaxis
ACU12_10885	COG0840	transmembrane signaling receptor activity
ACU12_10910	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACU12_10940	COG0318	PFAM AMP-dependent synthetase and ligase
ACU12_10945	COG1024	Enoyl-CoA hydratase
ACU12_10950	COG2198	Histidine kinase
ACU12_10950	COG2205	protein histidine kinase activity
ACU12_10950	COG0784	Response regulator, receiver
ACU12_10965	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ACU12_10985	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ACU12_10995	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ACU12_11000	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ACU12_11010	COG0505	Belongs to the CarA family
ACU12_11015	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ACU12_11020	COG2258	MOSC domain
ACU12_11025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACU12_11075	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ACU12_11100	COG0277	FAD linked oxidase domain protein
ACU12_11105	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ACU12_11115	COG0531	amino acid
ACU12_11120	COG0531	amino acid
ACU12_11125	COG0235	Class ii aldolase
ACU12_11155	COG0140	phosphoribosyl-ATP diphosphatase activity
ACU12_11155	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ACU12_11200	COG0124	histidyl-tRNA synthetase
ACU12_11215	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ACU12_11230	COG2963	transposase activity
ACU12_11235	COG2801	Transposase and inactivated derivatives
ACU12_11255	COG2963	transposase activity
ACU12_11280	COG1012	belongs to the aldehyde dehydrogenase family
ACU12_11300	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ACU12_11305	COG0697	spore germination
ACU12_11315	COG0671	phosphoesterase, PA-phosphatase related
ACU12_11330	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
ACU12_11335	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ACU12_11340	COG2203	Gaf domain
ACU12_11340	COG3706	GGDEF domain
ACU12_11340	COG4251	negative regulation of phosphorylation
ACU12_11340	COG5001	Diguanylate cyclase
ACU12_11350	COG1472	Belongs to the glycosyl hydrolase 3 family
ACU12_11375	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ACU12_11395	COG0617	tRNA 3'-terminal CCA addition
ACU12_11410	COG0860	N-Acetylmuramoyl-L-alanine amidase
ACU12_11415	COG0477	Major facilitator Superfamily
ACU12_11425	COG1070	Carbohydrate kinase
ACU12_11450	COG0800	Aldolase
ACU12_11465	COG3734	2-keto-3-deoxy-galactonokinase
ACU12_11470	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ACU12_11480	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACU12_11495	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ACU12_11500	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ACU12_11510	COG0352	thiamine-phosphate diphosphorylase activity
ACU12_11510	COG0351	phosphomethylpyrimidine kinase
ACU12_11535	COG0583	DNA-binding transcription factor activity
ACU12_11540	COG1741	Belongs to the pirin family
ACU12_11585	COG0402	S-adenosylhomocysteine deaminase activity
ACU12_11600	COG1509	lysine 2,3-aminomutase activity
ACU12_11605	COG3300	MHYT domain
ACU12_11605	COG5001	Diguanylate cyclase
ACU12_11620	COG0483	inositol monophosphate 1-phosphatase activity
ACU12_11650	COG0513	Belongs to the DEAD box helicase family
ACU12_11660	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ACU12_11670	COG0625	glutathione transferase activity
ACU12_11685	COG4681	YaeQ
ACU12_11690	COG2081	HI0933 family
ACU12_11710	COG1028	Short-chain dehydrogenase reductase Sdr
ACU12_11740	COG0802	atpase or kinase
ACU12_11745	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ACU12_11745	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ACU12_11750	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ACU12_11765	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ACU12_11820	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ACU12_11930	COG0835	chemotaxis
ACU12_11935	COG0840	transmembrane signaling receptor activity
ACU12_11955	COG2969	positive regulation of protein catabolic process
ACU12_11960	COG0625	glutathione transferase activity
ACU12_11965	COG2857	Cytochrome c1
ACU12_11970	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ACU12_11975	COG0723	plastoquinol--plastocyanin reductase activity
ACU12_11980	COG0741	lytic transglycosylase activity
ACU12_12000	COG1702	phosphate starvation-inducible protein PhoH
ACU12_12020	COG4535	Mg2 and Co2 transporter CorC
ACU12_12035	COG1012	belongs to the aldehyde dehydrogenase family
ACU12_12040	COG1177	transmembrane transport
ACU12_12045	COG1176	ABC-type spermidine putrescine transport system, permease component I
ACU12_12050	COG3842	ATPase activity
ACU12_12070	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ACU12_12085	COG3501	Rhs element vgr protein
ACU12_12100	COG2201	protein-glutamate methylesterase activity
ACU12_12105	COG2801	Transposase and inactivated derivatives
ACU12_12110	COG3501	Rhs element vgr protein
ACU12_12145	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ACU12_12150	COG0174	glutamine synthetase
ACU12_12155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACU12_12160	COG0745	RESPONSE REGULATOR receiver
ACU12_12160	COG3706	GGDEF domain
ACU12_12165	COG0477	Major facilitator Superfamily
ACU12_12170	COG0243	molybdopterin cofactor binding
ACU12_12190	COG1121	(ABC) transporter
ACU12_12200	COG2733	membrane
ACU12_12205	COG2205	protein histidine kinase activity
ACU12_12205	COG0784	Response regulator, receiver
ACU12_12205	COG5002	protein histidine kinase activity
ACU12_12225	COG2902	Dehydrogenase
ACU12_12235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACU12_12240	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACU12_12250	COG1609	Transcriptional regulator
ACU12_12255	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ACU12_12255	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACU12_12260	COG1105	Belongs to the carbohydrate kinase PfkB family
ACU12_12265	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ACU12_12265	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ACU12_12275	COG3039	Transposase
ACU12_12300	COG2801	Transposase and inactivated derivatives
ACU12_12320	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ACU12_12330	COG1862	Preprotein translocase
ACU12_12395	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ACU12_12415	COG0742	ribosomal rna small subunit methyltransferase
ACU12_12420	COG0326	Molecular chaperone. Has ATPase activity
ACU12_12465	COG1506	peptidase
ACU12_12465	COG0823	Involved in the tonB-independent uptake of proteins
ACU12_12480	COG4206	TonB-dependent receptor
ACU12_12530	COG0531	amino acid
ACU12_12545	COG0006	proline dipeptidase activity
ACU12_12555	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACU12_12570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACU12_12575	COG3938	Belongs to the proline racemase family
ACU12_12585	COG0552	protein localization to endoplasmic reticulum
ACU12_12595	COG1194	a g-specific adenine glycosylase
ACU12_12605	COG0784	Response regulator, receiver
ACU12_12605	COG4191	Histidine kinase
ACU12_12610	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ACU12_12635	COG3040	lipid binding
ACU12_12645	COG1960	acyl-CoA dehydrogenase activity
ACU12_12695	COG0438	transferase activity, transferring glycosyl groups
ACU12_12700	COG0438	transferase activity, transferring glycosyl groups
ACU12_12745	COG0776	regulation of translation
ACU12_12760	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ACU12_12765	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ACU12_12770	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ACU12_12780	COG2963	transposase activity
ACU12_12805	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ACU12_12825	COG0077	Prephenate dehydratase
ACU12_12825	COG1605	Chorismate mutase
ACU12_12830	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ACU12_12835	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ACU12_12885	COG2986	histidine ammonia-lyase
ACU12_12895	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ACU12_12915	COG2963	transposase activity
ACU12_12920	COG2801	Transposase and inactivated derivatives
ACU12_12930	COG0556	nucleotide-excision repair
ACU12_12935	COG4969	Belongs to the N-Me-Phe pilin family
ACU12_13000	COG4695	Portal protein
ACU12_13045	COG3179	chitinase
ACU12_13140	COG1192	Involved in chromosome partitioning
ACU12_13250	COG1611	Belongs to the LOG family
ACU12_13260	COG2095	MarC family integral membrane protein
ACU12_13270	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ACU12_13275	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ACU12_13310	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ACU12_13325	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ACU12_13330	COG0195	Participates in both transcription termination and antitermination
ACU12_13345	COG1007	ATP synthesis coupled electron transport
ACU12_13360	COG0713	ATP synthesis coupled electron transport
ACU12_13375	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ACU12_13380	COG1034	ATP synthesis coupled electron transport
ACU12_13385	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ACU12_13390	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
ACU12_13410	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACU12_13430	COG1028	Short-chain dehydrogenase reductase Sdr
ACU12_13435	COG3039	Transposase
ACU12_13485	COG0133	tryptophan synthase activity
ACU12_13515	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ACU12_13520	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ACU12_13530	COG2890	protein-(glutamine-N5) methyltransferase activity
ACU12_13550	COG0433	COG0433 Predicted ATPase
ACU12_13565	COG2801	Transposase and inactivated derivatives
ACU12_13580	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ACU12_13590	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACU12_13620	COG0489	protein tyrosine kinase activity
ACU12_13625	COG3293	Transposase
ACU12_13635	COG3706	GGDEF domain
ACU12_13645	COG3706	GGDEF domain
ACU12_13650	COG3039	Transposase
ACU12_13660	COG1028	Short-chain dehydrogenase reductase Sdr
ACU12_13675	COG0415	Belongs to the DNA photolyase family
ACU12_13680	COG0305	Participates in initiation and elongation during chromosome replication
ACU12_13690	COG0367	asparagine synthase
ACU12_13705	COG1960	acyl-CoA dehydrogenase activity
ACU12_13720	COG0084	hydrolase, TatD family'
ACU12_13725	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ACU12_13780	COG0386	Belongs to the glutathione peroxidase family
ACU12_13875	COG2814	Major facilitator Superfamily
ACU12_13880	COG1566	PFAM secretion protein HlyD family protein
ACU12_13895	COG2207	Transcriptional regulator
ACU12_13915	COG4774	siderophore transport
ACU12_13925	COG0367	asparagine synthase
ACU12_13930	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ACU12_13940	COG1393	Belongs to the ArsC family
ACU12_13960	COG0024	Methionine aminopeptidase
ACU12_14005	COG3706	GGDEF domain
ACU12_14005	COG0745	RESPONSE REGULATOR receiver
ACU12_14025	COG0575	Belongs to the CDS family
ACU12_14030	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ACU12_14035	COG0750	zinc metalloprotease
ACU12_14045	COG3039	Transposase
ACU12_14050	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACU12_14080	COG0825	malonyl-CoA metabolic process
ACU12_14125	COG1695	Transcriptional regulator
ACU12_14155	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ACU12_14165	COG2040	homocysteine
ACU12_14170	COG0833	amino acid
ACU12_14175	COG0346	lactoylglutathione lyase activity
ACU12_14215	COG1595	DNA-templated transcription, initiation
ACU12_14240	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ACU12_14255	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ACU12_14260	COG0251	oxidation-reduction process
ACU12_14270	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ACU12_14270	COG0392	lysyltransferase activity
ACU12_14300	COG2814	Major facilitator Superfamily
ACU12_14305	COG1902	pentaerythritol trinitrate reductase activity
ACU12_14320	COG2824	Alkylphosphonate utilization operon protein PhnA
ACU12_14330	COG1047	Peptidyl-prolyl cis-trans
ACU12_14365	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ACU12_14380	COG1451	nucleotide metabolic process
ACU12_14395	COG0183	Belongs to the thiolase family
ACU12_14425	COG1793	dna ligase
ACU12_14425	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ACU12_14435	COG1793	dna ligase
ACU12_14440	COG1201	RNA secondary structure unwinding
ACU12_14455	COG1278	Cold shock
ACU12_14460	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ACU12_14475	COG3046	protein related to deoxyribodipyrimidine photolyase
ACU12_14480	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
ACU12_14485	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ACU12_14525	COG0681	Belongs to the peptidase S26 family
ACU12_14530	COG0481	GTPase activity
ACU12_14535	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACU12_14575	COG1960	acyl-CoA dehydrogenase activity
ACU12_14635	COG5002	protein histidine kinase activity
ACU12_14635	COG0784	Response regulator, receiver
ACU12_14640	COG2826	transposase and inactivated derivatives, IS30 family
ACU12_14650	COG2353	YceI-like domain
ACU12_14680	COG1760	l-serine dehydratase
ACU12_14690	COG0626	cystathionine gamma-synthase activity
ACU12_14695	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACU12_14700	COG0739	heme binding
ACU12_14710	COG1272	protein, Hemolysin III
ACU12_14730	COG0517	IMP dehydrogenase activity
ACU12_14730	COG0516	GMP reductase activity
ACU12_14735	COG0463	Glycosyl transferase, family 2
ACU12_14745	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ACU12_14755	COG4771	TonB-dependent receptor
ACU12_14760	COG1309	transcriptional regulator
ACU12_14770	COG1960	acyl-CoA dehydrogenase activity
ACU12_14810	COG0330	HflC and HflK could
ACU12_14815	COG1742	UPF0060 membrane protein
ACU12_14820	COG3956	TIGRFAM MazG family protein
ACU12_14830	COG0494	nUDIX hydrolase
ACU12_14840	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ACU12_14845	COG0837	glucose binding
ACU12_14860	COG1388	LysM domain
ACU12_14860	COG3858	chitin binding
ACU12_14865	COG3525	Glycosyl hydrolase, family 20, catalytic domain
ACU12_14875	COG1472	Belongs to the glycosyl hydrolase 3 family
ACU12_14885	COG2826	transposase and inactivated derivatives, IS30 family
ACU12_14895	COG3537	Alpha-1,2-mannosidase
ACU12_14935	COG3142	Participates in the control of copper homeostasis
ACU12_14940	COG1446	asparaginase
ACU12_14980	COG0840	transmembrane signaling receptor activity
ACU12_14985	COG0835	chemotaxis
ACU12_15000	COG0189	ligase activity
ACU12_15010	COG1397	ADP-ribosylglycohydrolase
ACU12_15020	COG1199	ATP-dependent helicase activity
ACU12_15030	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ACU12_15045	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ACU12_15085	COG0837	glucose binding
ACU12_15090	COG0837	glucose binding
ACU12_15100	COG1643	Atp-dependent helicase
ACU12_15105	COG0783	Belongs to the Dps family
ACU12_15110	COG0514	ATP-dependent DNA helicase (RecQ)
ACU12_15125	COG1187	pseudouridine synthase activity
ACU12_15135	COG0840	transmembrane signaling receptor activity
ACU12_15170	COG0602	queuosine metabolic process
ACU12_15180	COG2885	chlorophyll binding
ACU12_15185	COG0823	Involved in the tonB-independent uptake of proteins
ACU12_15205	COG0824	Thioesterase
ACU12_15245	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ACU12_15260	COG0477	Major facilitator Superfamily
ACU12_15275	COG2755	lipolytic protein G-D-S-L family
ACU12_15275	COG0657	acetylesterase activity
ACU12_15295	COG0488	(ABC) transporter
ACU12_15330	COG4651	solute:proton antiporter activity
ACU12_15330	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ACU12_15350	COG4772	TonB-dependent receptor
ACU12_15360	COG4264	IucA IucC family
ACU12_15365	COG2814	Major facilitator Superfamily
ACU12_15375	COG0019	diaminopimelate decarboxylase activity
ACU12_15420	COG4206	TonB-dependent receptor
ACU12_15425	COG2801	Transposase and inactivated derivatives
ACU12_15430	COG2963	transposase activity
ACU12_15435	COG0542	response to heat
ACU12_15460	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
ACU12_15470	COG2826	transposase and inactivated derivatives, IS30 family
ACU12_15475	COG0534	Mate efflux family protein
ACU12_15520	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ACU12_15525	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ACU12_15565	COG2172	sigma factor antagonist activity
ACU12_15570	COG1366	Belongs to the anti-sigma-factor antagonist family
ACU12_15575	COG1366	Belongs to the anti-sigma-factor antagonist family
ACU12_15590	COG0326	Molecular chaperone. Has ATPase activity
ACU12_15595	COG2207	Transcriptional regulator
ACU12_15620	COG2963	transposase activity
ACU12_15640	COG3209	COG3209 Rhs family protein
ACU12_15680	COG3501	Rhs element vgr protein
ACU12_15690	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ACU12_15695	COG1845	cytochrome c oxidase, subunit III
ACU12_15700	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ACU12_15720	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ACU12_15730	COG0196	riboflavin kinase activity
ACU12_15735	COG0728	peptidoglycan biosynthetic process
ACU12_15740	COG0268	Binds directly to 16S ribosomal RNA
ACU12_15760	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ACU12_15765	COG0824	Thioesterase
ACU12_15780	COG1946	Acyl-CoA thioesterase
ACU12_15790	COG1595	DNA-templated transcription, initiation
ACU12_15820	COG3293	Transposase
ACU12_15850	COG1877	trehalose-phosphatase activity
ACU12_15855	COG3387	PFAM Glycoside hydrolase 15-related
ACU12_15870	COG0840	transmembrane signaling receptor activity
ACU12_15875	COG3011	Protein conserved in bacteria
ACU12_15890	COG0564	pseudouridine synthase activity
ACU12_15895	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACU12_15900	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ACU12_15900	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ACU12_15910	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ACU12_15930	COG2184	nucleotidyltransferase activity
ACU12_15950	COG2194	sulfuric ester hydrolase activity
ACU12_15955	COG4969	Belongs to the N-Me-Phe pilin family
ACU12_15965	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ACU12_15975	COG3039	Transposase
ACU12_15985	COG2826	transposase and inactivated derivatives, IS30 family
ACU12_16000	COG2963	transposase activity
ACU12_16025	COG0745	RESPONSE REGULATOR receiver
ACU12_16070	COG3039	Transposase
ACU12_16100	COG3501	Rhs element vgr protein
ACU12_16135	COG3273	potassium ion transport
ACU12_16135	COG0471	metal ion transport
ACU12_16155	COG1970	mechanosensitive ion channel activity
ACU12_16170	COG2963	transposase activity
ACU12_16180	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACU12_16200	COG0308	aminopeptidase N
ACU12_16205	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACU12_16215	COG2895	sulfate adenylyltransferase (ATP) activity
ACU12_16215	COG0529	Catalyzes the synthesis of activated sulfate
ACU12_16225	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ACU12_16255	COG0784	Response regulator, receiver
ACU12_16255	COG2205	protein histidine kinase activity
ACU12_16255	COG2198	Histidine kinase
ACU12_16290	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ACU12_16295	COG3588	fructose-bisphosphate aldolase
ACU12_16300	COG0469	pyruvate kinase activity
ACU12_16310	COG0126	phosphoglycerate kinase activity
ACU12_16320	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ACU12_16340	COG3453	Protein conserved in bacteria
ACU12_16340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACU12_16345	COG0725	ABC transporter, periplasmic molybdate-binding protein
ACU12_16350	COG4149	molybdate abc transporter
ACU12_16355	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ACU12_16455	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ACU12_16465	COG2963	transposase activity
ACU12_16470	COG2801	Transposase and inactivated derivatives
ACU12_16490	COG2304	oxidoreductase activity
ACU12_16510	COG0714	Associated with various cellular activities
ACU12_16540	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ACU12_16555	COG0254	rRNA binding
ACU12_16565	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ACU12_16575	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ACU12_16580	COG1758	RNA polymerase activity
ACU12_16590	COG1561	YicC-like family, N-terminal region
ACU12_16600	COG0346	lactoylglutathione lyase activity
ACU12_16610	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ACU12_16635	COG0006	proline dipeptidase activity
ACU12_16655	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ACU12_16675	COG2912	Transglutaminase-like superfamily
ACU12_16680	COG1773	rubredoxin
ACU12_16685	COG0352	thiamine-phosphate diphosphorylase activity
ACU12_16715	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ACU12_16750	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ACU12_16755	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ACU12_16775	COG1028	Short-chain dehydrogenase reductase Sdr
ACU12_16790	COG3781	membrane
ACU12_16800	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ACU12_16840	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
ACU12_16850	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ACU12_16870	COG3710	Transcriptional regulator
ACU12_16910	COG2226	methyltransferase
ACU12_16930	COG3706	GGDEF domain
ACU12_16940	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ACU12_16945	COG1538	Outer membrane efflux protein
ACU12_16950	COG1519	Transferase
ACU12_16955	COG1560	Kdo2-lipid A biosynthetic process
ACU12_16985	COG0280	phosphate acetyltransferase
ACU12_16985	COG0281	malic enzyme
ACU12_17000	COG4191	Histidine kinase
ACU12_17015	COG0583	DNA-binding transcription factor activity
ACU12_17040	COG2197	response regulator
ACU12_17045	COG1840	ABC-type Fe3 transport system, periplasmic component
ACU12_17050	COG0642	Histidine kinase
ACU12_17065	COG2851	Citrate transporter
ACU12_17070	COG1028	Short-chain dehydrogenase reductase Sdr
ACU12_17075	COG1609	Transcriptional regulator
ACU12_17080	COG2211	Major facilitator Superfamily
ACU12_17110	COG0436	Aminotransferase
ACU12_17125	COG0726	polysaccharide deacetylase
ACU12_17130	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ACU12_17150	COG3964	amidohydrolase
ACU12_17155	COG0402	S-adenosylhomocysteine deaminase activity
ACU12_17175	COG0242	peptide deformylase activity
ACU12_17190	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ACU12_17235	COG2188	Transcriptional regulator
ACU12_17245	COG1450	Type ii and iii secretion system protein
ACU12_17260	COG3166	PFAM Fimbrial assembly family protein
ACU12_17265	COG3156	type II secretion system protein K
ACU12_17270	COG4795	General secretion pathway protein
ACU12_17275	COG2165	general secretion pathway protein
ACU12_17280	COG4970	Tfp pilus assembly protein FimT
ACU12_17285	COG2165	general secretion pathway protein
ACU12_17290	COG1459	type II secretion system
ACU12_17300	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ACU12_17305	COG1404	Belongs to the peptidase S8 family
ACU12_17310	COG5295	Hep Hag repeat protein
ACU12_17315	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ACU12_17315	COG0047	phosphoribosylformylglycinamidine synthase activity
ACU12_17320	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ACU12_17325	COG4974	Belongs to the 'phage' integrase family
ACU12_17340	COG0795	lipopolysaccharide-transporting ATPase activity
ACU12_17365	COG0525	valine-tRNA ligase activity
ACU12_17390	COG1183	phosphatidylcholine synthase activity
ACU12_17415	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ACU12_17420	COG1127	ABC transporter
ACU12_17425	COG3218	ABC-type transport auxiliary lipoprotein component
ACU12_17425	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ACU12_17460	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACU12_17465	COG0662	Cupin 2, conserved barrel domain protein
ACU12_17465	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
ACU12_17490	COG2086	electron transfer activity
ACU12_17505	COG0546	phosphoglycolate phosphatase activity
ACU12_17505	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ACU12_17510	COG0277	FAD linked oxidase domain protein
ACU12_17525	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACU12_17550	COG2226	methyltransferase
ACU12_17560	COG3754	Rhamnan synthesis protein F
ACU12_17565	COG0438	transferase activity, transferring glycosyl groups
ACU12_17565	COG1216	Glycosyl transferase, family 2
ACU12_17570	COG0110	maltose O-acetyltransferase activity
ACU12_17585	COG0626	cystathionine gamma-synthase activity
ACU12_17620	COG0625	glutathione transferase activity
ACU12_17630	COG0513	Belongs to the DEAD box helicase family
ACU12_17635	COG0720	synthase
ACU12_17650	COG1956	GAF domain-containing protein
ACU12_17660	COG0546	phosphoglycolate phosphatase activity
ACU12_17685	COG0339	signal peptide processing
ACU12_17725	COG3039	Transposase
ACU12_17740	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ACU12_17745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACU12_17750	COG1136	(ABC) transporter
ACU12_17760	COG0577	efflux transmembrane transporter activity
ACU12_17760	COG1136	(ABC) transporter
ACU12_17770	COG0577	efflux transmembrane transporter activity
ACU12_17770	COG1136	(ABC) transporter
ACU12_17780	COG4191	Histidine kinase
ACU12_17835	COG0356	it plays a direct role in the translocation of protons across the membrane
ACU12_17855	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACU12_17865	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACU12_17900	COG2011	ABC-type metal ion transport system permease component
ACU12_17910	COG0697	spore germination
ACU12_17945	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACU12_17950	COG1187	pseudouridine synthase activity
ACU12_17955	COG2813	Specifically methylates the guanine in position
ACU12_17980	COG2205	protein histidine kinase activity
ACU12_17980	COG2202	Pas domain
ACU12_18005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACU12_18010	COG1522	sequence-specific DNA binding
ACU12_18050	COG0745	RESPONSE REGULATOR receiver
ACU12_18065	COG1404	Belongs to the peptidase S8 family
ACU12_18080	COG0842	Transport permease protein
ACU12_18085	COG1131	(ABC) transporter
ACU12_18090	COG0025	NhaP-type Na H and K H
ACU12_18095	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
ACU12_18100	COG1573	uracil-dna glycosylase
ACU12_18110	COG3384	dioxygenase
ACU12_18125	COG0667	Aldo Keto reductase
ACU12_18140	COG3590	peptidase
ACU12_18155	COG0531	amino acid
ACU12_18170	COG2972	Histidine kinase
ACU12_18210	COG1271	oxidase subunit
ACU12_18215	COG1294	oxidase, subunit
ACU12_18230	COG1063	alcohol dehydrogenase
ACU12_18310	COG2801	Transposase and inactivated derivatives
ACU12_18315	COG2353	YceI-like domain
ACU12_18350	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ACU12_18365	COG3386	PFAM SMP-30 Gluconolaconase
ACU12_18380	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ACU12_18395	COG0459	protein refolding
ACU12_18400	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ACU12_18430	COG2860	membrane
ACU12_18435	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ACU12_18445	COG2201	protein-glutamate methylesterase activity
ACU12_18450	COG2177	Part of the ABC transporter FtsEX involved in
ACU12_18455	COG2884	Cell division ATP-binding protein ftsE
ACU12_18465	COG3118	belongs to the thioredoxin family
ACU12_18470	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ACU12_18510	COG1473	amidohydrolase
ACU12_18515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACU12_18520	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACU12_18550	COG5383	Protein conserved in bacteria
ACU12_18590	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
ACU12_18595	COG3023	N-Acetylmuramoyl-L-alanine amidase
ACU12_18605	COG4948	Mandelate Racemase Muconate Lactonizing
ACU12_18615	COG0531	amino acid
ACU12_18630	COG4682	membrane
ACU12_18635	COG2133	pyrroloquinoline quinone binding
ACU12_18650	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ACU12_18660	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ACU12_18665	COG1610	YqeY-like protein
ACU12_18670	COG1295	ribonuclease BN
ACU12_18675	COG0358	DNA primase activity
ACU12_18725	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
ACU12_18740	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ACU12_18765	COG2963	transposase activity
ACU12_18800	COG0739	heme binding
ACU12_18815	COG2211	Major facilitator Superfamily
ACU12_18820	COG0708	Exodeoxyribonuclease III
ACU12_18860	COG2111	Na H antiporter
ACU12_18860	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ACU12_18865	COG1006	Multisubunit Na H antiporter MnhC subunit
ACU12_18870	COG0651	ATP synthesis coupled electron transport
ACU12_18880	COG2212	antiporter activity
ACU12_18885	COG1320	monovalent cation:proton antiporter activity
ACU12_18920	COG3104	oligopeptide transport
ACU12_18935	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ACU12_18950	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACU12_18960	COG3039	Transposase
ACU12_18965	COG3039	Transposase
ACU12_18975	COG0513	Belongs to the DEAD box helicase family
ACU12_19035	COG2963	transposase activity
ACU12_19040	COG2801	Transposase and inactivated derivatives
ACU12_19060	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACU12_19065	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACU12_19075	COG1042	CoA-binding domain protein
ACU12_19075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ACU12_19075	COG0045	succinate-CoA ligase (ADP-forming) activity
ACU12_19085	COG2239	Acts as a magnesium transporter
ACU12_19105	COG3039	Transposase
ACU12_19110	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ACU12_19115	COG3387	PFAM Glycoside hydrolase 15-related
ACU12_19130	COG3100	YcgL domain-containing protein
ACU12_19135	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ACU12_19145	COG0463	Glycosyl transferase, family 2
ACU12_19165	COG1028	Short-chain dehydrogenase reductase Sdr
ACU12_19210	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ACU12_19225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ACU12_19245	COG2826	transposase and inactivated derivatives, IS30 family
ACU12_19335	COG0210	DNA helicase
ACU12_19350	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ACU12_19355	COG0583	DNA-binding transcription factor activity
ACU12_19360	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ACU12_19370	COG2159	amidohydrolase
ACU12_19375	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ACU12_19380	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ACU12_19395	COG0357	Ribosomal RNA small subunit methyltransferase G
ACU12_19400	COG3540	Alkaline phosphatase
ACU12_19410	COG2091	lysine biosynthetic process via aminoadipic acid
ACU12_19425	COG0708	Exodeoxyribonuclease III
ACU12_19435	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACU12_19440	COG3162	membrane
ACU12_19475	COG1414	Transcriptional regulator
ACU12_19485	COG2205	protein histidine kinase activity
ACU12_19500	COG3459	Glycosyltransferase 36 associated
ACU12_19510	COG3265	gluconokinase activity
ACU12_19515	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACU12_19535	COG0339	signal peptide processing
ACU12_19560	COG0564	pseudouridine synthase activity
ACU12_19590	COG1181	Belongs to the D-alanine--D-alanine ligase family
ACU12_19605	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACU12_19610	COG0318	PFAM AMP-dependent synthetase and ligase
ACU12_19620	COG0596	Alpha beta hydrolase
ACU12_19625	COG3177	Filamentation induced by cAMP protein fic
ACU12_19630	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ACU12_19645	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ACU12_19670	COG2205	protein histidine kinase activity
ACU12_19675	COG0028	Belongs to the TPP enzyme family
ACU12_19690	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ACU12_19695	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ACU12_19735	COG0183	Belongs to the thiolase family
ACU12_19750	COG3039	Transposase
ACU12_19755	COG3039	Transposase
ACU12_19770	COG2032	superoxide dismutase activity
ACU12_19775	COG2032	superoxide dismutase activity
ACU12_19780	COG2204	response regulator
ACU12_19785	COG3852	Histidine kinase
ACU12_19790	COG0004	ammonium transporteR
ACU12_19795	COG0347	Belongs to the P(II) protein family
ACU12_19800	COG0174	glutamine synthetase
ACU12_19850	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ACU12_19860	COG2062	phosphohistidine phosphatase, SixA
ACU12_19865	COG0489	protein tyrosine kinase activity
ACU12_19885	COG1396	sequence-specific DNA binding
ACU12_19890	COG3550	peptidyl-serine autophosphorylation
ACU12_19895	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
ACU12_19900	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ACU12_19915	COG0517	IMP dehydrogenase activity
ACU12_19915	COG1125	glycine betaine transport
ACU12_19930	COG1119	ATPase activity
ACU12_19940	COG1473	amidohydrolase
ACU12_19945	COG1752	Esterase of the alpha-beta hydrolase superfamily
ACU12_19950	COG4773	Receptor
ACU12_19955	COG1522	sequence-specific DNA binding
ACU12_19960	COG3186	Phenylalanine-4-hydroxylase
ACU12_19980	COG1609	Transcriptional regulator
ACU12_20000	COG0366	Alpha amylase catalytic
ACU12_20005	COG0366	Alpha amylase catalytic
ACU12_20020	COG3039	Transposase
ACU12_20030	COG2963	transposase activity
ACU12_20085	COG0676	glucose-6-phosphate 1-epimerase activity
ACU12_20100	COG0730	response to heat
ACU12_20135	COG0302	gtp cyclohydrolase
ACU12_20160	COG0477	Major facilitator Superfamily
ACU12_20220	COG3237	CsbD-like
ACU12_20270	COG0477	Major facilitator Superfamily
ACU12_20290	COG3039	Transposase
ACU12_20295	COG2963	transposase activity
ACU12_20300	COG2801	Transposase and inactivated derivatives
ACU12_20305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACU12_20330	COG1755	Isoprenylcysteine carboxyl methyltransferase
ACU12_20340	COG3039	Transposase
ACU12_20350	COG4772	TonB-dependent receptor
ACU12_20360	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ACU12_20380	COG1272	protein, Hemolysin III
ACU12_20385	COG1111	helicase
ACU12_20385	COG1205	dead DEAH box helicase
ACU12_20435	COG0067	glutamate synthase
ACU12_20435	COG0069	glutamate synthase activity
ACU12_20435	COG0070	glutamate synthase
ACU12_20440	COG0493	'glutamate synthase
ACU12_20455	COG0531	amino acid
ACU12_20465	COG1322	Protein conserved in bacteria
ACU12_20475	COG0386	Belongs to the glutathione peroxidase family
ACU12_20480	COG2853	Lipoprotein
ACU12_20495	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ACU12_20500	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ACU12_20505	COG1127	ABC transporter
ACU12_20530	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ACU12_20535	COG1074	ATP-dependent DNA helicase activity
ACU12_20545	COG3549	Plasmid maintenance system killer
ACU12_20640	COG2124	cytochrome p450
ACU12_20645	COG2124	cytochrome p450
ACU12_20650	COG1141	Ferredoxin
ACU12_20655	COG1028	Short-chain dehydrogenase reductase Sdr
ACU12_20660	COG2124	cytochrome p450
ACU12_20665	COG0142	geranyltranstransferase activity
ACU12_20670	COG1657	PFAM Prenyltransferase squalene oxidase
ACU12_20680	COG1304	FMN binding
ACU12_20710	COG0564	pseudouridine synthase activity
ACU12_20735	COG3706	GGDEF domain
ACU12_20745	COG1929	Belongs to the glycerate kinase type-1 family
ACU12_20750	COG2271	Major facilitator Superfamily
ACU12_20765	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ACU12_20770	COG0861	Integral membrane protein TerC family
ACU12_20780	COG0584	glycerophosphoryl diester phosphodiesterase
ACU12_20790	COG0671	phosphoesterase, PA-phosphatase related
ACU12_20795	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ACU12_20800	COG0726	polysaccharide deacetylase
ACU12_20815	COG0230	Belongs to the bacterial ribosomal protein bL34 family